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Lisa M. Nogle, Ph.D.

Affiliations:

Oregon State University, Corvallis, OR

Area:

bioactive molecules with anticancer, antibacterial, neurotoxic, antiviral, or anti-inflammatory activity from marine organisms

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Mean distance: 10.06

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Parents

William H. Gerwick	grad student	2003	Oregon State
(Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites.)

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Publications

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Li D, Zhang H, Lyons TW, et al. (2021) Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors. Acs Medicinal Chemistry Letters. 12: 1678-1688
Hopkins BA, Lee H, Ha S, et al. (2019) Development of a Platform To Enable Efficient Permeability Evaluation of Novel Organo-Peptide Macrocycles. Acs Medicinal Chemistry Letters. 10: 874-879
Gavrin LK, Mahaney PE, Jenkins D, et al. (2010) Discovery of WAY-260022, a Potent and Selective Inhibitor of the Norepinephrine Transporter. Acs Medicinal Chemistry Letters. 1: 91-5
Simmons TL, Nogle LM, Media J, et al. (2009) Desmethoxymajusculamide C, a cyanobacterial depsipeptide with potent cytotoxicity in both cyclic and ring-opened forms. Journal of Natural Products. 72: 1011-6
Moore WJ, Kern JC, Bhat R, et al. (2009) Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides. Journal of Medicinal Chemistry. 52: 105-16
Goljer I, Molinari A, He Y, et al. (2009) Unexpected rearrangement of enantiomerically pure 3-aminoquinuclidine as a simple way of preparing diastereomeric octahydropyrrolo[2,3-c]pyridine derivatives. Chirality. 21: 681-91
McComas CC, Vu AT, Mahaney PE, et al. (2008) Synthesis and activity of 1-(3-amino-1-phenylpropyl)indolin-2-ones: a new class of selective norepinephrine reuptake inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 4929-31
McConnell O, Bach A, Balibar C, et al. (2007) Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery: building chiral technology toolboxes. Chirality. 19: 658-82
McConnell OJ, He Y, Nogle L, et al. (2007) Application of chiral technology in a pharmaceutical company. Enantiomeric separation and spectroscopic studies of key asymmetric intermediates using a combination of techniques. Phenylglycidols Chirality. 19: 716-730
Crawley ML, Goljer I, Jenkins DJ, et al. (2006) Regioselective synthesis of substituted pyrroles: efficient palladium-catalyzed cyclization of internal alkynes and 2-amino-3-iodoacrylate derivatives. Organic Letters. 8: 5837-40

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