Year |
Citation |
Score |
2021 |
Li D, Zhang H, Lyons TW, Lu M, Achab A, Pu Q, Childers M, Mitcheltree MJ, Wang J, Martinot TA, McMinn SE, Sloman DL, Palani A, Beard A, Nogle L, et al. Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors. Acs Medicinal Chemistry Letters. 12: 1678-1688. PMID 34795856 DOI: 10.1021/acsmedchemlett.1c00258 |
0.302 |
|
2019 |
Hopkins BA, Lee H, Ha S, Nogle L, Sauvagnat B, McMinn S, Smith GF, Sciammetta N. Development of a Platform To Enable Efficient Permeability Evaluation of Novel Organo-Peptide Macrocycles. Acs Medicinal Chemistry Letters. 10: 874-879. PMID 31223441 DOI: 10.1021/acsmedchemlett.9b00036 |
0.306 |
|
2010 |
Gavrin LK, Mahaney PE, Jenkins D, Nogle LM, Mugford CA, Huselton C, Leiter J, Johnston GH, Bray JA, Burroughs KD, Cosmi SA, Alfinito P, Ho DM, Deecher DC, Trybulski EJ. Discovery of WAY-260022, a Potent and Selective Inhibitor of the Norepinephrine Transporter. Acs Medicinal Chemistry Letters. 1: 91-5. PMID 24900182 DOI: 10.1021/Ml100009P |
0.319 |
|
2009 |
Simmons TL, Nogle LM, Media J, Valeriote FA, Mooberry SL, Gerwick WH. Desmethoxymajusculamide C, a cyanobacterial depsipeptide with potent cytotoxicity in both cyclic and ring-opened forms. Journal of Natural Products. 72: 1011-6. PMID 19489598 DOI: 10.1021/Np9001674 |
0.696 |
|
2009 |
Moore WJ, Kern JC, Bhat R, Commons TJ, Fukayama S, Goljer I, Krishnamurthy G, Magolda RL, Nogle L, Pitts K, Stauffer B, Trybulski EJ, Welmaker GS, Wilson M, Bodine PV. Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides. Journal of Medicinal Chemistry. 52: 105-16. PMID 19072540 DOI: 10.1021/Jm801144H |
0.325 |
|
2009 |
Goljer I, Molinari A, He Y, Nogle L, Sun W, Campbell B, McConnell O. Unexpected rearrangement of enantiomerically pure 3-aminoquinuclidine as a simple way of preparing diastereomeric octahydropyrrolo[2,3-c]pyridine derivatives. Chirality. 21: 681-91. PMID 18792960 DOI: 10.1002/Chir.20663 |
0.329 |
|
2008 |
McComas CC, Vu AT, Mahaney PE, Cohn ST, Fensome A, Marella MA, Nogle L, Trybulski EJ, Ye F, Zhang P, Alfinito P, Bray J, Johnston G, Koury E, Deecher DC. Synthesis and activity of 1-(3-amino-1-phenylpropyl)indolin-2-ones: a new class of selective norepinephrine reuptake inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 4929-31. PMID 18771916 DOI: 10.1016/J.Bmcl.2008.08.060 |
0.321 |
|
2007 |
McConnell O, Bach A, Balibar C, Byrne N, Cai Y, Carter G, Chlenov M, Di L, Fan K, Goljer I, He Y, Herold D, Kagan M, Kerns E, Koehn F, ... ... Nogle L, et al. Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery: building chiral technology toolboxes. Chirality. 19: 658-82. PMID 17390370 DOI: 10.1002/Chir.20399 |
0.667 |
|
2007 |
McConnell OJ, He Y, Nogle L, Sarkahian A. Application of chiral technology in a pharmaceutical company. Enantiomeric separation and spectroscopic studies of key asymmetric intermediates using a combination of techniques. Phenylglycidols Chirality. 19: 716-730. PMID 17323324 DOI: 10.1002/Chir.20368 |
0.388 |
|
2006 |
Crawley ML, Goljer I, Jenkins DJ, Mehlmann JF, Nogle L, Dooley R, Mahaney PE. Regioselective synthesis of substituted pyrroles: efficient palladium-catalyzed cyclization of internal alkynes and 2-amino-3-iodoacrylate derivatives. Organic Letters. 8: 5837-40. PMID 17134285 DOI: 10.1021/Ol062424P |
0.303 |
|
2006 |
Mahaney PE, Vu AT, McComas CC, Zhang P, Nogle LM, Watts WL, Sarkahian A, Leventhal L, Sullivan NR, Uveges AJ, Trybulski EJ. Synthesis and activity of a new class of dual acting norepinephrine and serotonin reuptake inhibitors: 3-(1H-indol-1-yl)-3-arylpropan-1-amines. Bioorganic & Medicinal Chemistry. 14: 8455-66. PMID 16973367 DOI: 10.1016/J.Bmc.2006.08.039 |
0.314 |
|
2006 |
Nogle LM, Mann CW, Watts WL, Zhang Y. Preparative separation and identification of derivatized beta-methylphenylalanine enantiomers by chiral SFC, HPLC and NMR for development of new peptide ligand mimetics in drug discovery. Journal of Pharmaceutical and Biomedical Analysis. 40: 901-9. PMID 16239092 DOI: 10.1016/J.Jpba.2005.08.034 |
0.392 |
|
2004 |
Edwards DJ, Marquez BL, Nogle LM, McPhail K, Goeger DE, Roberts MA, Gerwick WH. Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula. Chemistry & Biology. 11: 817-33. PMID 15217615 DOI: 10.1016/J.Chembiol.2004.03.030 |
0.698 |
|
2003 |
Nogle LM, Gerwick WH. Diverse secondary metabolites from a Puerto Rican collection of Lyngbyamajuscula. Journal of Natural Products. 66: 217-20. PMID 12608852 DOI: 10.1021/Np020332C |
0.575 |
|
2003 |
Nogle LM, Marquez BL, Gerwick WH. Wewakazole, a novel cyclic dodecapeptide from a Papua New Guinea Lyngbya majuscula. Organic Letters. 5: 3-6. PMID 12509876 DOI: 10.1021/Ol026811K |
0.701 |
|
2002 |
Nogle LM, Gerwick WH. Somocystinamide A, a novel cytotoxic disulfide dimer from a Fijian marine cyanobacterial mixed assemblage. Organic Letters. 4: 1095-8. PMID 11922791 DOI: 10.1021/Ol017275J |
0.531 |
|
2002 |
Nogle LM, Gerwick WH. Isolation of four new cyclic depsipeptides, antanapeptins A-D, and dolastatin 16 from a Madagascan collection of Lyngbya majuscula. Journal of Natural Products. 65: 21-4. PMID 11809058 DOI: 10.1021/Np010348N |
0.567 |
|
2001 |
Nogle LM, Okino T, Gerwick WH. Antillatoxin B, a neurotoxic lipopeptide from the marine cyanobacterium Lyngbya majuscula. Journal of Natural Products. 64: 983-5. PMID 11473443 DOI: 10.1021/Np010107F |
0.542 |
|
2001 |
Nogle LM, Williamson RT, Gerwick WH. Somamides A and B, two new depsipeptide analogues of dolastatin 13 from a Fijian cyanobacterial assemblage of Lyngbya majuscula and Schizothrix species. Journal of Natural Products. 64: 716-9. PMID 11421730 DOI: 10.1021/Np000634J |
0.625 |
|
2000 |
Wu M, Okino T, Nogle LM, Marquez BL, Williamson RT, Sitachitta N, Berman FW, Murray TF, McGough K, Jacobs R, Colsen K, Asano T, Yokokawa F, Shioiri T, Gerwick WH. Structure, synthesis, and biological properties of kalkitoxin, a novel neurotoxin from the marine cyanobacterium Lyngbya majuscula [24] Journal of the American Chemical Society. 122: 12041-12042. DOI: 10.1021/Ja005526Y |
0.618 |
|
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