W. Ford Doolittle, PhD - Publications

Affiliations: 
Biochemistry and Molecular Biology Dalhousie University, Halifax, Nova Scotia, Canada 
Area:
genome evolution

212 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Doolittle WF. Evolution: Two Domains of Life or Three? Current Biology. 30. PMID 32097647 DOI: 10.1016/J.Cub.2020.01.010  0.334
2020 Novick A, Doolittle WF. Horizontal persistence and the complexity hypothesis Biology and Philosophy. 35: 1-22. DOI: 10.1007/S10539-019-9727-6  0.461
2019 Wideman JG, Novick A, Muñoz-Gómez SA, Doolittle WF. Neutral evolution of cellular phenotypes. Current Opinion in Genetics & Development. 58: 87-94. PMID 31574422 DOI: 10.1016/J.Gde.2019.09.004  0.811
2019 Doolittle WF. Making Evolutionary Sense of Gaia Trends in Ecology and Evolution. 34: 889-894. PMID 31155421 DOI: 10.1016/J.Tree.2019.05.001  0.312
2019 Wideman JG, Inkpen SA, Doolittle WF, Redfield RJ. Mutationism, not Lamarckism, captures the novelty of CRISPR–Cas Biology & Philosophy. 34. DOI: 10.1007/S10539-018-9659-6  0.656
2018 Doolittle WF, Inkpen SA. Processes and patterns of interaction as units of selection: An introduction to ITSNTS thinking. Proceedings of the National Academy of Sciences of the United States of America. 115: 4006-4014. PMID 29581311 DOI: 10.1073/Pnas.1722232115  0.372
2018 Mariscal C, Doolittle WF. Life and life only: a radical alternative to life definitionism Synthese. 197: 2975-2989. DOI: 10.1007/S11229-018-1852-2  0.75
2018 Brunet TDP, Doolittle WF. The generality of Constructive Neutral Evolution Biology and Philosophy. 33: 2. DOI: 10.1007/S10539-018-9614-6  0.371
2017 Doolittle WF, Brunet TDP. On causal roles and selected effects: our genome is mostly junk. Bmc Biology. 15: 116. PMID 29207982 DOI: 10.1186/S12915-017-0460-9  0.388
2017 Doolittle WF. Making the Most of Clade Selection Philosophy of Science. 84: 275-295. DOI: 10.1086/690719  0.323
2017 Doolittle WF, Booth A. It’s the song, not the singer: an exploration of holobiosis and evolutionary theory Biology and Philosophy. 32: 5-24. DOI: 10.1007/S10539-016-9542-2  0.705
2016 Eme L, Doolittle WF. Microbial Evolution: Xenology (Apparently) Trumps Paralogy. Current Biology : Cb. 26: R1181-R1183. PMID 27875695 DOI: 10.1016/J.Cub.2016.09.049  0.743
2016 Booth A, Mariscal C, Doolittle WF. The Modern Synthesis in the Light of Microbial Genomics. Annual Review of Microbiology. PMID 27482743 DOI: 10.1146/Annurev-Micro-102215-095456  0.794
2016 Doolittle WF, Brunet TD. What Is the Tree of Life? Plos Genetics. 12: e1005912. PMID 27078870 DOI: 10.1371/Journal.Pgen.1005912  0.366
2015 Eme L, Doolittle WF. Archaea. Current Biology : Cb. 25: R851-5. PMID 26439345 DOI: 10.1016/j.cub.2015.05.025  0.646
2015 Mariscal C, Doolittle WF. Eukaryotes first: how could that be? Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370: 20140322. PMID 26323754 DOI: 10.1098/Rstb.2014.0322  0.792
2015 Booth A, Doolittle WF. Reply to Lane and Martin: Being and becoming eukaryotes. Proceedings of the National Academy of Sciences of the United States of America. 112: E4824. PMID 26283404 DOI: 10.1073/Pnas.1513285112  0.712
2015 Keeling PJ, McCutcheon JP, Doolittle WF. Symbiosis becoming permanent: Survival of the luckiest. Proceedings of the National Academy of Sciences of the United States of America. 112: 10101-3. PMID 26283342 DOI: 10.1073/Pnas.1513346112  0.619
2015 Brunet TD, Doolittle WF. Multilevel Selection Theory and the Evolutionary Functions of Transposable Elements. Genome Biology and Evolution. 7: 2445-57. PMID 26253318 DOI: 10.1093/Gbe/Evv152  0.364
2015 Booth A, Doolittle WF. Eukaryogenesis, how special really? Proceedings of the National Academy of Sciences of the United States of America. PMID 25883267 DOI: 10.1073/Pnas.1421376112  0.703
2015 Eme L, Doolittle WF. Microbial diversity: a bonanza of phyla. Current Biology : Cb. 25: R227-30. PMID 25784040 DOI: 10.1016/J.Cub.2014.12.044  0.695
2015 Doolittle WF. Rethinking the tree of life: Even though lateral gene transfers tend to undermine this beloved metaphor, the underlying theory of evolution is very much intact Microbe. 10: 319-323. DOI: 10.1128/Microbe.10.319.1  0.474
2014 Hahn MW, Schmidt J, Taipale SJ, Doolittle WF, Koll U. Rhodoluna lacicola gen. nov., sp. nov., a planktonic freshwater bacterium with stream-lined genome. International Journal of Systematic and Evolutionary Microbiology. 64: 3254-63. PMID 24984700 DOI: 10.1099/Ijs.0.065292-0  0.334
2014 Doolittle WF, Brunet TD, Linquist S, Gregory TR. Distinguishing between "function" and "effect" in genome biology. Genome Biology and Evolution. 6: 1234-7. PMID 24814287 DOI: 10.1093/Gbe/Evu098  0.352
2014 Doolittle WF. The trouble with (group II) introns. Proceedings of the National Academy of Sciences of the United States of America. 111: 6536-7. PMID 24757059 DOI: 10.1073/Pnas.1405174111  0.431
2013 Doolittle WF, Fraser P, Gerstein MB, Graveley BR, Henikoff S, Huttenhower C, Oshlack A, Ponting CP, Rinn JL, Schatz MC, Ule J, Weigel D, Weinstock GM. Sixty years of genome biology. Genome Biology. 14: 113. PMID 23651518 DOI: 10.1186/Gb-2013-14-4-113  0.344
2012 Zhaxybayeva O, Swithers KS, Foght J, Green AG, Bruce D, Detter C, Han S, Teshima H, Han J, Woyke T, Pitluck S, Nolan M, Ivanova N, Pati A, Land ML, ... ... Doolittle WF, et al. Genome sequence of the mesophilic Thermotogales bacterium Mesotoga prima MesG1.Ag.4.2 reveals the largest Thermotogales genome to date. Genome Biology and Evolution. 4: 700-8. PMID 22798451 DOI: 10.1093/Gbe/Evs059  0.729
2012 Doolittle WF. Population genomics: how bacterial species form and why they don't exist. Current Biology : Cb. 22: R451-3. PMID 22677288 DOI: 10.1016/J.Cub.2012.04.034  0.359
2012 Doolittle WF. Evolutionary biology: A ratchet for protein complexity. Nature. 481: 270-1. PMID 22230958 DOI: 10.1038/Nature10816  0.397
2011 Lukeš J, Archibald JM, Keeling PJ, Doolittle WF, Gray MW. How a neutral evolutionary ratchet can build cellular complexity. Iubmb Life. 63: 528-37. PMID 21698757 DOI: 10.1002/Iub.489  0.761
2011 Doolittle WF, Lukeš J, Archibald JM, Keeling PJ, Gray MW. Comment on "Does constructive neutral evolution play an important role in the origin of cellular complexity?" DOI 10.1002/bies.201100010. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 33: 427-9. PMID 21538416 DOI: 10.1002/Bies.201100039  0.768
2011 Zhaxybayeva O, Doolittle WF. Lateral gene transfer. Current Biology : Cb. 21: R242-6. PMID 21481756 DOI: 10.1016/J.Cub.2011.01.045  0.714
2011 Koenig JE, Bourne DG, Curtis B, Dlutek M, Stokes HW, Doolittle WF, Boucher Y. Coral-mucus-associated Vibrio integrons in the Great Barrier Reef: genomic hotspots for environmental adaptation. The Isme Journal. 5: 962-72. PMID 21270840 DOI: 10.1038/Ismej.2010.193  0.633
2010 Gray MW, Lukes J, Archibald JM, Keeling PJ, Doolittle WF. Cell biology. Irremediable complexity? Science (New York, N.Y.). 330: 920-1. PMID 21071654 DOI: 10.1126/Science.1198594  0.724
2010 Nesbø CL, Kumaraswamy R, Dlutek M, Doolittle WF, Foght J. Searching for mesophilic Thermotogales bacteria: "mesotogas" in the wild. Applied and Environmental Microbiology. 76: 4896-900. PMID 20495053 DOI: 10.1128/Aem.02846-09  0.351
2010 Rose MR, Doolittle WF. Molecular biological mechanisms of speciation. Science (New York, N.Y.). 220: 157-62. PMID 17795801 DOI: 10.1126/Science.220.4593.157  0.371
2010 Doolittle WF, Zhaxybayeva O. Metagenomics and the units of biological organization Bioscience. 60: 102-112. DOI: 10.1525/Bio.2010.60.2.5  0.65
2010 Doolittle WF. The attempt on the life of the Tree of Life: Science, philosophy and politics Biology and Philosophy. 25: 455-473. DOI: 10.1007/S10539-010-9210-X  0.362
2009 Zhaxybayeva O, Doolittle WF, Papke RT, Gogarten JP. Intertwined evolutionary histories of marine Synechococcus and Prochlorococcus marinus. Genome Biology and Evolution. 1: 325-39. PMID 20333202 DOI: 10.1093/Gbe/Evp032  0.78
2009 Jezbera J, Sharma AK, Brandt U, Doolittle WF, Hahn MW. 'Candidatus Planktophila limnetica', an actinobacterium representing one of the most numerically important taxa in freshwater bacterioplankton. International Journal of Systematic and Evolutionary Microbiology. 59: 2864-9. PMID 19628588 DOI: 10.1099/Ijs.0.010199-0  0.356
2009 Doolittle WF. The practice of classification and the theory of evolution, and what the demise of Charles Darwin's tree of life hypothesis means for both of them. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 364: 2221-8. PMID 19571242 DOI: 10.1098/Rstb.2009.0032  0.394
2009 Doolittle WF, Zhaxybayeva O. On the origin of prokaryotic species. Genome Research. 19: 744-56. PMID 19411599 DOI: 10.1101/Gr.086645.108  0.657
2009 Koenig JE, Sharp C, Dlutek M, Curtis B, Joss M, Boucher Y, Doolittle WF. Integron gene cassettes and degradation of compounds associated with industrial waste: the case of the Sydney tar ponds. Plos One. 4: e5276. PMID 19390587 DOI: 10.1371/Journal.Pone.0005276  0.639
2009 Joss MJ, Koenig JE, Labbate M, Polz MF, Gillings MR, Stokes HW, Doolittle WF, Boucher Y. ACID: annotation of cassette and integron data. Bmc Bioinformatics. 10: 118. PMID 19383137 DOI: 10.1186/1471-2105-10-118  0.734
2009 Zhaxybayeva O, Swithers KS, Lapierre P, Fournier GP, Bickhart DM, DeBoy RT, Nelson KE, Nesbø CL, Doolittle WF, Gogarten JP, Noll KM. On the chimeric nature, thermophilic origin, and phylogenetic placement of the Thermotogales. Proceedings of the National Academy of Sciences of the United States of America. 106: 5865-70. PMID 19307556 DOI: 10.1073/Pnas.0901260106  0.816
2009 Sharma AK, Sommerfeld K, Bullerjahn GS, Matteson AR, Wilhelm SW, Jezbera J, Brandt U, Doolittle WF, Hahn MW. Actinorhodopsin genes discovered in diverse freshwater habitats and among cultivated freshwater Actinobacteria. The Isme Journal. 3: 726-37. PMID 19242530 DOI: 10.1038/Ismej.2009.13  0.473
2009 Nesbø CL, Bapteste E, Curtis B, Dahle H, Lopez P, Macleod D, Dlutek M, Bowman S, Zhaxybayeva O, Birkeland NK, Doolittle WF. The genome of Thermosipho africanus TCF52B: lateral genetic connections to the Firmicutes and Archaea. Journal of Bacteriology. 191: 1974-8. PMID 19124572 DOI: 10.1128/Jb.01448-08  0.734
2008 Beiko RG, Doolittle WF, Charlebois RL. The impact of reticulate evolution on genome phylogeny. Systematic Biology. 57: 844-56. PMID 19085328 DOI: 10.1080/10635150802559265  0.387
2008 Sharma AK, Zhaxybayeva O, Papke RT, Doolittle WF. Actinorhodopsins: proteorhodopsin-like gene sequences found predominantly in non-marine environments. Environmental Microbiology. 10: 1039-56. PMID 18218036 DOI: 10.1111/J.1462-2920.2007.01525.X  0.725
2008 Koenig JE, Boucher Y, Charlebois RL, Nesbø C, Zhaxybayeva O, Bapteste E, Spencer M, Joss MJ, Stokes HW, Doolittle WF. Integron-associated gene cassettes in Halifax Harbour: assessment of a mobile gene pool in marine sediments. Environmental Microbiology. 10: 1024-38. PMID 18190517 DOI: 10.1111/J.1462-2920.2007.01524.X  0.777
2008 Bapteste E, Susko E, Leigh J, Ruiz-Trillo I, Bucknam J, Doolittle WF. Alternative methods for concatenation of core genes indicate a lack of resolution in deep nodes of the prokaryotic phylogeny. Molecular Biology and Evolution. 25: 83-91. PMID 17940208 DOI: 10.1093/Molbev/Msm229  0.828
2007 Papke RT, Zhaxybayeva O, Feil EJ, Sommerfeld K, Muise D, Doolittle WF. Searching for species in haloarchaea. Proceedings of the National Academy of Sciences of the United States of America. 104: 14092-7. PMID 17715057 DOI: 10.1073/pnas.0706358104  0.679
2007 Doolittle WF, Zhaxybayeva O. Evolution: reducible complexity -- the case for bacterial flagella. Current Biology : Cb. 17: R510-2. PMID 17610831 DOI: 10.1016/J.Cub.2007.05.003  0.637
2007 Zhaxybayeva O, Gogarten JP, Doolittle WF. A hyperconserved protein in Prochlorococcus and marine Synechococcus. Fems Microbiology Letters. 274: 30-4. PMID 17573933 DOI: 10.1111/J.1574-6968.2007.00806.X  0.768
2007 Zhaxybayeva O, Nesbø CL, Doolittle WF. Systematic overestimation of gene gain through false diagnosis of gene absence. Genome Biology. 8: 402. PMID 17328791 DOI: 10.1186/Gb-2007-8-2-402  0.714
2007 Doolittle WF, Bapteste E. Pattern pluralism and the Tree of Life hypothesis. Proceedings of the National Academy of Sciences of the United States of America. 104: 2043-9. PMID 17261804 DOI: 10.1073/Pnas.0610699104  0.374
2007 Case RJ, Boucher Y, Dahllöf I, Holmström C, Doolittle WF, Kjelleberg S. Use of 16S rRNA and rpoB genes as molecular markers for microbial ecology studies. Applied and Environmental Microbiology. 73: 278-88. PMID 17071787 DOI: 10.1128/Aem.01177-06  0.682
2006 Doolittle WF, Papke RT. Genomics and the bacterial species problem. Genome Biology. 7: 116. PMID 17020593 DOI: 10.1186/Gb-2006-7-9-116  0.359
2006 Sharma AK, Spudich JL, Doolittle WF. Microbial rhodopsins: functional versatility and genetic mobility. Trends in Microbiology. 14: 463-9. PMID 17008099 DOI: 10.1016/J.Tim.2006.09.006  0.383
2006 Gophna U, Sommerfeld K, Gophna S, Doolittle WF, Veldhuyzen van Zanten SJ. Differences between tissue-associated intestinal microfloras of patients with Crohn's disease and ulcerative colitis. Journal of Clinical Microbiology. 44: 4136-41. PMID 16988016 DOI: 10.1128/Jcm.01004-06  0.56
2006 Zhaxybayeva O, Gogarten JP, Charlebois RL, Doolittle WF, Papke RT. Phylogenetic analyses of cyanobacterial genomes: quantification of horizontal gene transfer events. Genome Research. 16: 1099-108. PMID 16899658 DOI: 10.1101/Gr.5322306  0.8
2006 Nesbø CL, Dlutek M, Zhaxybayeva O, Doolittle WF. Evidence for existence of "mesotogas," members of the order Thermotogales adapted to low-temperature environments. Applied and Environmental Microbiology. 72: 5061-8. PMID 16820506 DOI: 10.1128/Aem.00342-06  0.709
2006 Legault BA, Lopez-Lopez A, Alba-Casado JC, Doolittle WF, Bolhuis H, Rodriguez-Valera F, Papke RT. Environmental genomics of "Haloquadratum walsbyi" in a saltern crystallizer indicates a large pool of accessory genes in an otherwise coherent species. Bmc Genomics. 7: 171. PMID 16820057 DOI: 10.1186/1471-2164-7-171  0.489
2006 Susko E, Leigh J, Doolittle WF, Bapteste E. Visualizing and assessing phylogenetic congruence of core gene sets: a case study of the gamma-proteobacteria. Molecular Biology and Evolution. 23: 1019-30. PMID 16495350 DOI: 10.1093/Molbev/Msj113  0.771
2006 Boucher Y, Nesbø CL, Joss MJ, Robinson A, Mabbutt BC, Gillings MR, Doolittle WF, Stokes HW. Recovery and evolutionary analysis of complete integron gene cassette arrays from Vibrio. Bmc Evolutionary Biology. 6: 3. PMID 16417647 DOI: 10.1186/1471-2148-6-3  0.671
2006 Gophna U, Charlebois RL, Doolittle WF. Ancient lateral gene transfer in the evolution of Bdellovibrio bacteriovorus. Trends in Microbiology. 14: 64-9. PMID 16413191 DOI: 10.1016/J.Tim.2005.12.008  0.676
2006 Nesbø CL, Dlutek M, Doolittle WF. Recombination in Thermotoga: implications for species concepts and biogeography. Genetics. 172: 759-69. PMID 16322518 DOI: 10.1534/Genetics.105.049312  0.458
2006 Gophna U, Thompson JR, Boucher Y, Doolittle WF. Complex histories of genes encoding 3-hydroxy-3-methylglutaryl-CoenzymeA reductase. Molecular Biology and Evolution. 23: 168-78. PMID 16162862 DOI: 10.1093/Molbev/Msj019  0.731
2006 Nesbø CL, Doolittle WF, Mongodin EF, Nelson KE. Outside forces helped shape the Thermotoga metagenome Microbe. 1: 235-241. DOI: 10.1128/Microbe.1.235.1  0.488
2005 Mongodin EF, Nelson KE, Daugherty S, Deboy RT, Wister J, Khouri H, Weidman J, Walsh DA, Papke RT, Sanchez Perez G, Sharma AK, Nesbø CL, MacLeod D, Bapteste E, Doolittle WF, et al. The genome of Salinibacter ruber: convergence and gene exchange among hyperhalophilic bacteria and archaea. Proceedings of the National Academy of Sciences of the United States of America. 102: 18147-52. PMID 16330755 DOI: 10.1073/Pnas.0509073102  0.396
2005 Nesbø CL, Boucher Y, Dlutek M, Doolittle WF. Lateral gene transfer and phylogenetic assignment of environmental fosmid clones. Environmental Microbiology. 7: 2011-26. PMID 16309397 DOI: 10.1111/J.1462-2920.2005.00918.X  0.666
2005 Gophna U, Bapteste E, Doolittle WF, Biran D, Ron EZ. Evolutionary plasticity of methionine biosynthesis. Gene. 355: 48-57. PMID 16046084 DOI: 10.1016/J.Gene.2005.05.028  0.656
2005 Bapteste E, Susko E, Leigh J, MacLeod D, Charlebois RL, Doolittle WF. Do orthologous gene phylogenies really support tree-thinking? Bmc Evolutionary Biology. 5: 33. PMID 15913459 DOI: 10.1186/1471-2148-5-33  0.787
2005 Walsh DA, Doolittle WF. The real 'domains' of life. Current Biology : Cb. 15: R237-40. PMID 15823519 DOI: 10.1016/J.Cub.2005.03.034  0.353
2005 Gophna U, Doolittle WF, Charlebois RL. Weighted genome trees: refinements and applications. Journal of Bacteriology. 187: 1305-16. PMID 15687194 DOI: 10.1128/Jb.187.4.1305-1316.2005  0.654
2004 Papke RT, Koenig JE, Rodríguez-Valera F, Doolittle WF. Frequent recombination in a saltern population of Halorubrum. Science (New York, N.Y.). 306: 1928-9. PMID 15591201 DOI: 10.1126/Science.1103289  0.378
2004 Charlebois RL, Doolittle WF. Computing prokaryotic gene ubiquity: rescuing the core from extinction. Genome Research. 14: 2469-77. PMID 15574825 DOI: 10.1101/Gr.3024704  0.483
2004 Dacks JB, Doolittle WF. Molecular and phylogenetic characterization of syntaxin genes from parasitic protozoa. Molecular and Biochemical Parasitology. 136: 123-36. PMID 15478792 DOI: 10.1016/J.Molbiopara.2004.02.014  0.632
2004 Walsh DA, Bapteste E, Kamekura M, Doolittle WF. Evolution of the RNA polymerase B' subunit gene (rpoB') in Halobacteriales: a complementary molecular marker to the SSU rRNA gene. Molecular Biology and Evolution. 21: 2340-51. PMID 15356285 DOI: 10.1093/Molbev/Msh248  0.504
2004 Bapteste E, Boucher Y, Leigh J, Doolittle WF. Phylogenetic reconstruction and lateral gene transfer. Trends in Microbiology. 12: 406-11. PMID 15337161 DOI: 10.1016/J.Tim.2004.07.002  0.827
2004 Boucher Y, Douady CJ, Sharma AK, Kamekura M, Doolittle WF. Intragenomic heterogeneity and intergenomic recombination among haloarchaeal rRNA genes. Journal of Bacteriology. 186: 3980-90. PMID 15175312 DOI: 10.1128/Jb.186.12.3980-3990.2004  0.668
2004 Gophna U, Charlebois RL, Doolittle WF. Have archaeal genes contributed to bacterial virulence? Trends in Microbiology. 12: 213-9. PMID 15120140 DOI: 10.1016/J.Tim.2004.03.002  0.666
2004 Boucher Y, Kamekura M, Doolittle WF. Origins and evolution of isoprenoid lipid biosynthesis in archaea. Molecular Microbiology. 52: 515-27. PMID 15066037 DOI: 10.1111/J.1365-2958.2004.03992.X  0.602
2004 Doolittle WF. W. Ford Doolittle. Current Biology : Cb. 14: R176-7. PMID 15028226 DOI: 10.1016/J.Cub.2004.02.010  0.39
2003 Dacks JB, Davis LA, Sjögren AM, Andersson JO, Roger AJ, Doolittle WF. Evidence for Golgi bodies in proposed 'Golgi-lacking' lineages. Proceedings. Biological Sciences / the Royal Society. 270: S168-71. PMID 14667372 DOI: 10.1098/Rsbl.2003.0058  0.768
2003 Nesbø CL, Doolittle WF. Targeting clusters of transferred genes in Thermotoga maritima. Environmental Microbiology. 5: 1144-54. PMID 14641594 DOI: 10.1046/J.1462-2920.2003.00515.X  0.411
2003 Papke RT, Douady CJ, Doolittle WF, Rodríguez-Valera F. Diversity of bacteriorhodopsins in different hypersaline waters from a single Spanish saltern. Environmental Microbiology. 5: 1039-45. PMID 14641583 DOI: 10.1046/J.1462-2920.2003.00501.X  0.405
2003 Boucher Y, Douady CJ, Papke RT, Walsh DA, Boudreau ME, Nesbø CL, Case RJ, Doolittle WF. Lateral gene transfer and the origins of prokaryotic groups. Annual Review of Genetics. 37: 283-328. PMID 14616063 DOI: 10.1146/Annurev.Genet.37.050503.084247  0.663
2003 Nesbø CL, Doolittle WF. Active self-splicing group I introns in 23S rRNA genes of hyperthermophilic bacteria, derived from introns in eukaryotic organelles. Proceedings of the National Academy of Sciences of the United States of America. 100: 10806-11. PMID 12947037 DOI: 10.1073/Pnas.1434268100  0.463
2003 Papke RT, Doolittle WF. Phage evolution: new worlds of genomic diversity. Current Biology : Cb. 13: R606-7. PMID 12906814 DOI: 10.1016/S0960-9822(03)00527-X  0.414
2003 Moriya S, Dacks JB, Takagi A, Noda S, Ohkuma M, Doolittle WF, Kudo T. Molecular phylogeny of three oxymonad genera: Pyrsonympha, Dinenympha and Oxymonas. The Journal of Eukaryotic Microbiology. 50: 190-7. PMID 12836875 DOI: 10.1111/J.1550-7408.2003.Tb00115.X  0.616
2003 Douady CJ, Delsuc F, Boucher Y, Doolittle WF, Douzery EJ. Comparison of Bayesian and maximum likelihood bootstrap measures of phylogenetic reliability. Molecular Biology and Evolution. 20: 248-54. PMID 12598692 DOI: 10.1093/Molbev/Msg042  0.551
2003 Doolittle WF, Boucher Y, Nesbø CL, Douady CJ, Andersson JO, Roger AJ. How big is the iceberg of which organellar genes in nuclear genomes are but the tip? Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 358: 39-57; discussion 57. PMID 12594917 DOI: 10.1098/Rstb.2002.1185  0.774
2002 Gogarten JP, Doolittle WF, Lawrence JG. Prokaryotic evolution in light of gene transfer. Molecular Biology and Evolution. 19: 2226-38. PMID 12446813 DOI: 10.1093/Oxfordjournals.Molbev.A004046  0.702
2002 O'Malley MA, Roger AJ, Doolittle WF. Can commercial protection be good for research? Nature. 419: 111. PMID 12226635 DOI: 10.1038/419111A  0.653
2002 Nesbø CL, Nelson KE, Doolittle WF. Suppressive subtractive hybridization detects extensive genomic diversity in Thermotoga maritima. Journal of Bacteriology. 184: 4475-88. PMID 12142418 DOI: 10.1128/Jb.184.16.4475-4488.2002  0.491
2002 Inagaki Y, Doolittle WF, Baldauf SL, Roger AJ. Lateral transfer of an EF-1alpha gene: origin and evolution of the large subunit of ATP sulfurylase in eubacteria. Current Biology : Cb. 12: 772-6. PMID 12007424 DOI: 10.1016/S0960-9822(02)00816-3  0.817
2002 Boucher Y, Doolittle WF. Something new under the sea. Nature. 417: 27-8. PMID 11986648 DOI: 10.1038/417027A  0.536
2002 Dacks JB, Doolittle WF. Novel syntaxin gene sequences from Giardia, Trypanosoma and algae: implications for the ancient evolution of the eukaryotic endomembrane system. Journal of Cell Science. 115: 1635-42. PMID 11950882  0.598
2002 Archibald JM, O'Kelly CJ, Doolittle WF. The chaperonin genes of jakobid and jakobid-like flagellates: implications for eukaryotic evolution. Molecular Biology and Evolution. 19: 422-31. PMID 11919283 DOI: 10.1093/Oxfordjournals.Molbev.A004097  0.769
2002 Inagaki Y, Blouin C, Doolittle WF, Roger AJ. Convergence and constraint in eukaryotic release factor 1 (eRF1) domain 1: the evolution of stop codon specificity. Nucleic Acids Research. 30: 532-44. PMID 11788716 DOI: 10.1093/Nar/30.2.532  0.663
2002 Doolittle WF. Thinking laterally about genes Nature. 418: 589-590. DOI: 10.1038/418589A  0.429
2001 Noël C, Gerbod D, Fast NM, Wintjens R, Delgado-Viscogliosi P, Doolittle WF, Viscogliosi E. Tubulins in Trichomonas vaginalis: molecular characterization of alpha-tubulin genes, posttranslational modifications, and homology modeling of the tubulin dimer. The Journal of Eukaryotic Microbiology. 48: 647-54. PMID 11831773 DOI: 10.1111/J.1550-7408.2001.Tb00204.X  0.375
2001 Dacks JB, Doolittle WF. Reconstructing/deconstructing the earliest eukaryotes: how comparative genomics can help. Cell. 107: 419-25. PMID 11719183 DOI: 10.1016/S0092-8674(01)00584-0  0.63
2001 Nesbø CL, Boucher Y, Doolittle WF. Defining the core of nontransferable prokaryotic genes: the euryarchaeal core. Journal of Molecular Evolution. 53: 340-50. PMID 11675594 DOI: 10.1007/S002390010224  0.67
2001 Archibald JM, Blouin C, Doolittle WF. Gene duplication and the evolution of group II chaperonins: implications for structure and function. Journal of Structural Biology. 135: 157-69. PMID 11580265 DOI: 10.1006/Jsbi.2001.4353  0.747
2001 She Q, Singh RK, Confalonieri F, Zivanovic Y, Allard G, Awayez MJ, Chan-Weiher CC, Clausen IG, Curtis BA, De Moors A, Erauso G, Fletcher C, Gordon PM, Heikamp-de Jong I, Jeffries AC, ... ... Doolittle WF, et al. The complete genome of the crenarchaeon Sulfolobus solfataricus P2. Proceedings of the National Academy of Sciences of the United States of America. 98: 7835-40. PMID 11427726 DOI: 10.1073/Pnas.141222098  0.394
2001 Boucher Y, Huber H, L'Haridon S, Stetter KO, Doolittle WF. Bacterial origin for the isoprenoid biosynthesis enzyme HMG-CoA reductase of the archaeal orders Thermoplasmatales and Archaeoglobales. Molecular Biology and Evolution. 18: 1378-88. PMID 11420376 DOI: 10.1093/Oxfordjournals.Molbev.A003922  0.652
2001 Boucher Y, Nesbø CL, Doolittle WF. Microbial genomes: dealing with diversity. Current Opinion in Microbiology. 4: 285-9. PMID 11378480 DOI: 10.1016/S1369-5274(00)00204-6  0.618
2001 Andersson JO, Doolittle WF, Nesbø CL. Genomics. Are there bugs in our genome? Science (New York, N.Y.). 292: 1848-50. PMID 11358998 DOI: 10.1126/Science.1062241  0.654
2001 Nesbo CL, L'Haridon S, Stetter KO, Doolittle WF. Phylogenetic analyses of two "archaeal" genes in thermotoga maritima reveal multiple transfers between archaea and bacteria. Molecular Biology and Evolution. 18: 362-75. PMID 11230537 DOI: 10.1093/Oxfordjournals.Molbev.A003812  0.512
2001 Inagaki Y, Doolittle WF. Class I release factors in ciliates with variant genetic codes. Nucleic Acids Research. 29: 921-7. PMID 11160924 DOI: 10.1093/Nar/29.4.921  0.577
2000 Inagaki Y, Dacks JB, Doolittle WF, Watanabe KI, Ohama T. Evolutionary relationship between dinoflagellates bearing obligate diatom endosymbionts: insight into tertiary endosymbiosis. International Journal of Systematic and Evolutionary Microbiology. 50: 2075-81. PMID 11155982 DOI: 10.1099/00207713-50-6-2075  0.713
2000 Van de Peer Y, Baldauf SL, Doolittle WF, Meyer A. An updated and comprehensive rRNA phylogeny of (crown) eukaryotes based on rate-calibrated evolutionary distances. Journal of Molecular Evolution. 51: 565-76. PMID 11116330 DOI: 10.1007/S002390010120  0.704
2000 Baldauf SL, Roger AJ, Wenk-Siefert I, Doolittle WF. A kingdom-level phylogeny of eukaryotes based on combined protein data Science. 290: 972-977. PMID 11062127 DOI: 10.1126/Science.290.5493.972  0.734
2000 Archibald JM, Logsdon JM, Doolittle WF. Origin and evolution of eukaryotic chaperonins: phylogenetic evidence for ancient duplications in CCT genes. Molecular Biology and Evolution. 17: 1456-66. PMID 11018153 DOI: 10.1093/Oxfordjournals.Molbev.A026246  0.78
2000 Boucher Y, Doolittle WF. The role of lateral gene transfer in the evolution of isoprenoid biosynthesis pathways. Molecular Microbiology. 37: 703-16. PMID 10972794 DOI: 10.1046/J.1365-2958.2000.02004.X  0.644
2000 Doolittle WF. The nature of the universal ancestor and the evolution of the proteome. Current Opinion in Structural Biology. 10: 355-8. PMID 10851188 DOI: 10.1016/S0959-440X(00)00096-8  0.45
2000 Inagaki Y, Doolittle WF. Evolution of the eukaryotic translation termination system: Origins of release factors Molecular Biology and Evolution. 17: 882-889. PMID 10833194 DOI: 10.1093/Oxfordjournals.Molbev.A026368  0.6
2000 Faguy DM, Doolittle WF. Horizontal transfer of catalase-peroxidase genes between archaea and pathogenic bacteria. Trends in Genetics : Tig. 16: 196-7. PMID 10782109 DOI: 10.1016/S0168-9525(00)02007-2  0.406
2000 Charlebois RL, Singh RK, Chan-Weiher CC, Allard G, Chow C, Confalonieri F, Curtis B, Duguet M, Erauso G, Faguy D, Gaasterland T, Garrett RA, Gordon P, Jeffries AC, Kozera C, ... ... Doolittle WF, et al. Gene content and organization of a 281-kbp contig from the genome of the extremely thermophilic archaeon, Sulfolobus solfataricus P2. Genome / National Research Council Canada = Gã©Nome / Conseil National De Recherches Canada. 43: 116-36. PMID 10701121 DOI: 10.1139/G99-108  0.383
1999 Doolittle WF. Lateral genomics. Trends in Cell Biology. 9: M5-8. PMID 10611671 DOI: 10.1016/S0168-9525(99)01877-6  0.353
1999 Archibald JM, Logsdon JM, Doolittle WF. Recurrent paralogy in the evolution of archaeal chaperonins. Current Biology : Cb. 9: 1053-6. PMID 10508614 DOI: 10.1016/S0960-9822(99)80457-6  0.779
1999 Brown JR, Doolittle WF. Gene descent, duplication, and horizontal transfer in the evolution of glutamyl- and glutaminyl-tRNA synthetases. Journal of Molecular Evolution. 49: 485-95. PMID 10486006 DOI: 10.1007/Pl00006571  0.589
1999 Doolittle WF. Phylogenetic classification and the universal tree. Science (New York, N.Y.). 284: 2124-9. PMID 10381871 DOI: 10.1126/science.284.5423.2124  0.436
1999 Fast NM, Doolittle WF. Trichomonas vaginalis possesses a gene encoding the essential spliceosomal component, PRP8. Molecular and Biochemical Parasitology. 99: 275-8. PMID 10340492 DOI: 10.1016/S0166-6851(99)00017-1  0.408
1999 Roger AJ, Sandblom O, Doolittle WF, Philippe H. An evaluation of elongation factor 1 alpha as a phylogenetic marker for eukaryotes. Molecular Biology and Evolution. 16: 218-33. PMID 10028289  0.472
1999 Hirt RP, Logsdon JM, Healy B, Dorey MW, Doolittle WF, Embley TM. Microsporidia are related to Fungi: evidence from the largest subunit of RNA polymerase II and other proteins. Proceedings of the National Academy of Sciences of the United States of America. 96: 580-5. PMID 9892676 DOI: 10.1073/pnas.96.2.580  0.311
1998 Keeling PJ, Klenk HP, Singh RK, Schenk ME, Sensen CW, Zillig W, Doolittle WF. Sulfolobus islandicus plasmids pRN1 and pRN2 share distant but common evolutionary ancestry. Extremophiles : Life Under Extreme Conditions. 2: 391-3. PMID 9827327 DOI: 10.1007/S007920050083  0.653
1998 Doolittle WF. You are what you eat: a gene transfer ratchet could account for bacterial genes in eukaryotic nuclear genomes. Trends in Genetics : Tig. 14: 307-11. PMID 9724962 DOI: 10.1016/S0168-9525(98)01494-2  0.503
1998 Logsdon JM, Stoltzfus A, Doolittle WF. Molecular evolution: recent cases of spliceosomal intron gain? Current Biology : Cb. 8: R560-3. PMID 9707398 DOI: 10.1016/S0960-9822(07)00361-2  0.708
1998 Fast NM, Roger AJ, Richardson CA, Doolittle WF. U2 and U6 snRNA genes in the microsporidian Nosema locustae: evidence for a functional spliceosome. Nucleic Acids Research. 26: 3202-7. PMID 9628919 DOI: 10.1093/Nar/26.13.3202  0.567
1998 Doolittle WF, Logsdon JM. Archaeal genomics: do archaea have a mixed heritage? Current Biology : Cb. 8: R209-11. PMID 9512414 DOI: 10.1016/S0960-9822(98)70127-7  0.457
1998 Doolittle WF, Akam M. Genomes and evolution Current Opinion in Genetics and Development. 8: 613-615. DOI: 10.1016/S0959-437X(98)80027-0  0.359
1997 Brown JR, Doolittle WF. Archaea and the prokaryote-to-eukaryote transition. Microbiology and Molecular Biology Reviews : Mmbr. 61: 456-502. PMID 9409149  0.511
1997 Stoltzfus A, Logsdon JM, Palmer JD, Doolittle WF. Intron "sliding" and the diversity of intron positions. Proceedings of the National Academy of Sciences of the United States of America. 94: 10739-44. PMID 9380704 DOI: 10.1073/Pnas.94.20.10739  0.762
1997 Baldauf SL, Doolittle WF. Origin and evolution of the slime molds (Mycetozoa) Proceedings of the National Academy of Sciences of the United States of America. 94: 12007-12. PMID 9342353 DOI: 10.1073/Pnas.94.22.12007  0.718
1997 Keeling PJ, Doolittle WF. Widespread and ancient distribution of a noncanonical genetic code in diplomonads. Molecular Biology and Evolution. 14: 895-901. PMID 9287422 DOI: 10.1093/Oxfordjournals.Molbev.A025832  0.623
1997 Edgell DR, Doolittle WF. Archaea and the origin(s) of DNA replication proteins. Cell. 89: 995-8. PMID 9215620 DOI: 10.1016/S0092-8674(00)80285-8  0.395
1997 Brown JR, Robb FT, Weiss R, Doolittle WF. Evidence for the early divergence of tryptophanyl- and tyrosyl-tRNA synthetases. Journal of Molecular Evolution. 45: 9-16. PMID 9211729 DOI: 10.1007/Pl00006206  0.527
1997 Charlebois RL, Sensen CW, Doolittle WF, Brown JR. Evolutionary analysis of the hisCGABdFDEHI gene cluster from the archaeon Sulfolobus solfataricus P2. Journal of Bacteriology. 179: 4429-32. PMID 9209067 DOI: 10.1128/Jb.179.13.4429-4432.1997  0.485
1997 Bochar DA, Brown JR, Doolittle WF, Klenk HP, Lam W, Schenk ME, Stauffacher CV, Rodwell VW. 3-hydroxy-3-methylglutaryl coenzyme A reductase of Sulfolobus solfataricus: DNA sequence, phylogeny, expression in Escherichia coli of the hmgA gene, and purification and kinetic characterization of the gene product. Journal of Bacteriology. 179: 3632-8. PMID 9171410 DOI: 10.1128/Jb.179.11.3632-3638.1997  0.441
1997 Logsdon JM, Doolittle WF. Origin of antifreeze protein genes: a cool tale in molecular evolution. Proceedings of the National Academy of Sciences of the United States of America. 94: 3485-7. PMID 9108001 DOI: 10.1073/Pnas.94.8.3485  0.349
1997 Keeling PJ, Doolittle WF. Evidence that eukaryotic triosephosphate isomerase is of alpha-proteobacterial origin. Proceedings of the National Academy of Sciences of the United States of America. 94: 1270-5. PMID 9037042 DOI: 10.1073/Pnas.94.4.1270  0.697
1997 Edgell DR, Doolittle WF. Archaebacterial genomics: The complete genome sequence of Methanococcus jannaschii Bioessays. 19: 1-4. DOI: 10.1002/Bies.950190102  0.402
1996 Roger AJ, Smith MW, Doolittle RF, Doolittle WF. Evidence for the Heterolobosea from phylogenetic analysis of genes encoding glyceraldehyde-3-phosphate dehydrogenase. The Journal of Eukaryotic Microbiology. 43: 475-85. PMID 8976605 DOI: 10.1111/J.1550-7408.1996.Tb04507.X  0.567
1996 Keeling PJ, Doherty-Kirby AL, Teh EM, Doolittle WF. Linked genes for calmodulin and E2 ubiquitin-conjugating enzyme in Trichomonas vaginalis. The Journal of Eukaryotic Microbiology. 43: 468-74. PMID 8976604 DOI: 10.1111/J.1550-7408.1996.Tb04506.X  0.701
1996 Roger AJ, Clark CG, Doolittle WF. A possible mitochondrial gene in the early-branching amitochondriate protist Trichomonas vaginalis Proceedings of the National Academy of Sciences of the United States of America. 93: 14618-14622. PMID 8962102 DOI: 10.1073/pnas.93.25.14618  0.555
1996 Keeling PJ, Doolittle WF. Alpha-tubulin from early-diverging eukaryotic lineages and the evolution of the tubulin family. Molecular Biology and Evolution. 13: 1297-305. PMID 8952074 DOI: 10.1093/Oxfordjournals.Molbev.A025576  0.62
1996 Ragan MA, Logsdon JM, Sensen CW, Charlebois RL, Doolittle WF. An archaebacterial homolog of pelota, a meiotic cell division protein in eukaryotes. Fems Microbiology Letters. 144: 151-5. PMID 8900058 DOI: 10.1111/J.1574-6968.1996.Tb08522.X  0.329
1996 Keeling PJ, Doolittle WF. Methionine aminopeptidase-1: the MAP of the mitochondrion? Trends in Biochemical Sciences. 21: 285-6. PMID 8772380 DOI: 10.1016/S0968-0004(96)20017-9  0.538
1996 Baldauf SL, Palmer JD, Doolittle WF. The root of the universal tree and the origin of eukaryotes based on elongation factor phylogeny Proceedings of the National Academy of Sciences of the United States of America. 93: 7749-7754. PMID 8755547 DOI: 10.1073/Pnas.93.15.7749  0.755
1996 Keeling PJ, Klenk HP, Singh RK, Feeley O, Schleper C, Zillig W, Doolittle WF, Sensen CW. Complete nucleotide sequence of the Sulfolobus islandicus multicopy plasmid pRN1. Plasmid. 35: 141-4. PMID 8700967 DOI: 10.1006/Plas.1996.0016  0.666
1996 Charlebois RL, Gaasterland T, Ragan MA, Doolittle WF, Sensen CW. The Sulfolobus solfataricus P2 genome project. Febs Letters. 389: 88-91. PMID 8682213 DOI: 10.1016/0014-5793(96)00525-X  0.426
1996 Keeling PJ, Doolittle WF. A non-canonical genetic code in an early diverging eukaryotic lineage. The Embo Journal. 15: 2285-90. PMID 8641293 DOI: 10.1002/J.1460-2075.1996.Tb00581.X  0.629
1996 Keeling PJ, Baldauf SL, Doolittle WF, Zillig W, Klenk HP. An infB-homolog in Sulfolobus acidocaldarius Systematic and Applied Microbiology. 19: 312-321. DOI: 10.1016/S0723-2020(96)80057-9  0.709
1996 Keeling PJ, Baldauf SL, Doolittle WF, Zillig W, Klenk H. An infB-Homolog in Sulfolobus acidocaldarius Systematic and Applied Microbiology. 19: 312-321. DOI: 10.1016/S0723-2020(96)80057-9  0.749
1995 Stoltzfus A, Spencer DF, Doolittle WF. Methods for evaluating exon-protein correspondences Bioinformatics. 11: 509-515. PMID 8590174 DOI: 10.1093/Bioinformatics/11.5.509  0.719
1995 Brown JR, Doolittle WF. Root of the universal tree of life based on ancient aminoacyl-tRNA synthetase gene duplications Proceedings of the National Academy of Sciences of the United States of America. 92: 2441-2445. PMID 7708661 DOI: 10.1073/pnas.92.7.2441  0.523
1995 Keeling PJ, Doolittle WF. Archaea: narrowing the gap between prokaryotes and eukaryotes. Proceedings of the National Academy of Sciences of the United States of America. 92: 5761-4. PMID 7597025 DOI: 10.1073/Pnas.92.13.5761  0.666
1995 Keeling PJ, Doolittle WF. An archaebacterial elF-1A: new grist for the mill. Molecular Microbiology. 17: 399-400. PMID 7494488 DOI: 10.1111/j.1365-2958.1995.mmi_17020399.x  0.5
1995 Keeling PJ, Doolittle WF. Concerted evolution in protists: recent homogenization of a polyubiquitin gene in Trichomonas vaginalis. Journal of Molecular Evolution. 41: 556-62. PMID 7490769 DOI: 10.1007/Bf00175813  0.701
1994 Doolittle WF, Brown JR. Tempo, mode, the progenote, and the universal root Proceedings of the National Academy of Sciences of the United States of America. 91: 6721-6728. PMID 8041689 DOI: 10.1073/pnas.91.15.6721  0.347
1994 Stoltzfus A, Spencer DF, Zuker M, Logsdon JM, Doolittle WF. Testing the exon theory of genes: the evidence from protein structure. Science (New York, N.Y.). 265: 202-7. PMID 8023140 DOI: 10.1126/Science.8023140  0.716
1994 Roger AJ, Keeling PJ, Doolittle WF. Introns, the broken transposons. Society of General Physiologists Series. 49: 27-37. PMID 7939900  0.68
1994 Brown JR, Masuchi Y, Robb FT, Doolittle WF. Evolutionary relationships of bacterial and archaeal glutamine synthetase genes. Journal of Molecular Evolution. 38: 566-76. PMID 7916055 DOI: 10.1007/BF00175876  0.513
1994 Keeling PJ, Charlebois RL, Doolittle WF. Archaebacterial genomes: eubacterial form and eukaryotic content. Current Opinion in Genetics & Development. 4: 816-22. PMID 7888750 DOI: 10.1016/0959-437X(94)90065-5  0.664
1994 Klenk HP, Doolittle WF. Evolution: Archaea and eukaryotes versus bacteria? Current Biology. 4: 920-922. PMID 7850430 DOI: 10.1016/S0960-9822(00)00206-2  0.368
1993 Doolittle WF, Stoltzfus A. Molecular evolution. Genes-in-pieces revisited Nature. 361: 403. PMID 8429878 DOI: 10.1038/361403A0  0.735
1993 Roger AJ, Doolittle WF. Why introns-in-pieces? Nature. 364: 289-290. PMID 8332184 DOI: 10.1038/364289a0  0.466
1993 Doolittle WF, Stoltzfus A. Genes-in-pieces revisited Nature. 361: 403.  0.319
1991 Doolittle WF. The origins of introns. Current Biology : Cb. 1: 145-6. PMID 15336149 DOI: 10.1016/0960-9822(91)90214-H  0.353
1991 Charlebois RL, Schalkwyk LC, Hofman JD, Doolittle WF. Detailed physical map and set of overlapping clones covering the genome of the archaebacterium Haloferax volcanii DS2 Journal of Molecular Biology. 222: 509-524. PMID 1748993 DOI: 10.1016/0022-2836(91)90493-P  0.36
1989 Charlebois RL, Hofman JD, Schalkwyk LC, Lam WL, Doolittle WF. Genome mapping in halobacteria Canadian Journal of Microbiology. 35: 21-29. PMID 2470484 DOI: 10.1139/m89-004  0.306
1988 Doolittle WF. Hierarchical Approaches to Genome Evolution Canadian Journal of Philosophy. 18: 101-133. DOI: 10.1080/00455091.1988.10715946  0.343
1987 Drouin G, Hofman JD, Doolittle WF. Unusual ribosomal RNA gene organization in copepods of the genus Calanus Journal of Molecular Biology. 196: 943-946. PMID 3681983 DOI: 10.1016/0022-2836(87)90417-7  0.395
1987 Doolittle WF. The evolutionary significance of the Archaebacteria Annals of the New York Academy of Sciences. 503: 72-77. PMID 2441638 DOI: 10.1111/J.1749-6632.1987.Tb40598.X  0.354
1987 Doolittle WF. The Origin and Function of Intervening Sequences in DNA: A Review The American Naturalist. 130: 915-928. DOI: 10.1086/284755  0.466
1986 Hofman JD, Schalkwyk LC, Doolittle WF. ISH51: A large, degenerate family of insertion sequence-like elements in the genome of the archaehacterium, Halobacterium volcanii Nucleic Acids Research. 14: 6983-7000. PMID 3020501 DOI: 10.1093/Nar/14.17.6983  0.376
1986 Daniels CJ, Douglas SE, Doolittle WF. Genes for transfer RNAs in Halobacterium volcanii Systematic and Applied Microbiology. 7: 26-29. DOI: 10.1016/S0723-2020(86)80119-9  0.452
1985 Daniels CJ, Hofman JD, MacWilliam JG, Doolittle WF, Woese CR, Luehrsen KR, Fox GE. Sequence of 5S ribosomal RNA gene regions and their products in the archaebacterium Halobacterium volcanii. Molecular & General Genetics : Mgg. 198: 270-4. PMID 3856725 DOI: 10.1007/Bf00383005  0.443
1985 Daniels CJ, Gupta R, Doolittle WF. Transcription and excision of a large intron in the tRNATrp gene of an archaebacterium, Halobacterium volcanii. The Journal of Biological Chemistry. 260: 3132-4. PMID 3844407  0.368
1984 Walker WF, Doolittle WF. 5S rRNA sequences from eight basidiomycetes and fungi imperfecti. Nucleic Acids Research. 11: 7625-30. PMID 6647033 DOI: 10.1093/Nar/11.21.7625  0.332
1984 Douglas SE, Doolittle WF. Complete nucleotide sequence of the 23S rRNA gene of the Cyanobacterium, Anacystis nidulans. Nucleic Acids Research. 12: 3373-86. PMID 6326060 DOI: 10.1093/Nar/12.7.3373  0.47
1984 Douglas SE, Doolittle W. Nucleotide sequence of the 5 S rRNA gene and flanking regions in the cyanobacterium, Anacystis nidulans Febs Letters. 166: 307-310. DOI: 10.1016/0014-5793(84)80101-5  0.312
1983 MacKay RM, Doolittle WF. Two thraustochytrid 5S ribosomal RNAs. Nucleic Acids Research. 10: 8307-10. PMID 7162992 DOI: 10.1093/Nar/10.24.8307  0.324
1983 Walker WF, Doolittle WF. Nucleotide sequences of 5S ribosomal RNA from four oomycete and chytrid water molds. Nucleic Acids Research. 10: 5717-21. PMID 6890670 DOI: 10.1093/Nar/10.18.5717  0.335
1983 Xu WL, Doolittle WF. Structure of the archaebacterial transposable element ISH50. Nucleic Acids Research. 11: 4195-9. PMID 6306577 DOI: 10.1093/Nar/11.12.4195  0.31
1983 Williamson SE, Doolittle WF. Genes for tRNAIle and tRNAAla in the spacer between the 16S and 23S rRNA genes of a blue-green alga: strong homology to chloroplast tRNA genes and tRNA genes of the E. coli rrnD gene cluster. Nucleic Acids Research. 11: 225-35. PMID 6306565 DOI: 10.1093/Nar/11.1.225  0.47
1983 Walker WF, Doolittle WF. 5S rRNA sequences from four marine invertebrates and implications for base pairing models of metazoan sequences. Nucleic Acids Research. 11: 5159-64. PMID 6136024 DOI: 10.1093/Nar/11.15.5159  0.347
1983 Walker WF, Doolittle WF. Systematics of basidiomycetes based on 5S rRNA sequences and other data (reply) Nature. 303: 732-732. DOI: 10.1038/303732A0  0.32
1982 Sapienza C, Rose MR, Doolittle WF. High-frequency genomic rearrangements involving archaebacterial repeat sequency elements Nature. 299: 182-185. PMID 7110340 DOI: 10.1038/299182A0  0.363
1982 MacKay RM, Spencer DF, Schnare MN, Doolittle WF, Gray MW. Comparative sequence analysis as an approach to evaluating structure, function, and evolution of 5S and 5.8S ribosomal RNAs. Canadian Journal of Biochemistry. 60: 480-9. PMID 7104825 DOI: 10.1139/O82-057  0.345
1982 MacKay RM, Salgado D, Bonen L, Stackebrandt E, Doolittle WF. The 5S ribosomal RNAs of Paracoccus denitrificans and Prochloron. Nucleic Acids Research. 10: 2963-70. PMID 7099971 DOI: 10.1093/Nar/10.9.2963  0.346
1982 Sapienza C, Doolittle WF. Unusual physical organization of the Halobacterium genome Nature. 295: 384-389. PMID 7057904 DOI: 10.1038/295384A0  0.391
1982 Walker WF, Doolittle WF. Redividing the basidiomycetes on the basis of 5S rRNA sequences. Nature. 299: 723-724. PMID 6985484 DOI: 10.1038/299723A0  0.4
1982 Sapienza C, Doolittle WF. Genes are things you have whether you want them or not. Cold Spring Harbor Symposia On Quantitative Biology. 177-82. PMID 6271463 DOI: 10.1101/sqb.1981.045.01.028  0.318
1982 Sapienza C, Doolittle WF. Repeated Sequences in the Genomes of Halobacteria Zentralblatt FüR Bakteriologie Mikrobiologie Und Hygiene: I. Abt. Originale C: Allgemeine, Angewandte Und öKologische Mikrobiologie. 3: 120-127. DOI: 10.1016/S0721-9571(82)80060-4  0.363
1981 MacKay RM, Gray MW, Doolittle WF. Nucleotide sequence of Crithidia fasciculata cytosol 5S ribosomal ribonucleic acid. Nucleic Acids Research. 8: 4911-7. PMID 7443528 DOI: 10.1093/Nar/8.21.4911  0.346
1981 MacKay RM, Doolittle WF. Nucleotide sequences of Acanthamoeba castellanii 5S and 5.8S ribosomal ribonucleic acids: phylogenetic and comparative structural analyses. Nucleic Acids Research. 9: 3321-34. PMID 7279665 DOI: 10.1093/Nar/9.14.3321  0.343
1981 Doolittle WF. 5 S ribosomal RNA genes and the AluI family: evolutionary and functional significance of a region of strong homology. Febs Letters. 126: 147-9. PMID 7238867 DOI: 10.1016/0014-5793(81)80227-X  0.375
1981 Mackay RM, Spencer DF, Doolittle WF, Gray MW. Nucleotide sequences of wheat-embryo cytosol 5-S and 5.8-S ribosomal ribonucleic acids. European Journal of Biochemistry. 112: 561-76. PMID 6780349 DOI: 10.1111/J.1432-1033.1980.Tb06122.X  0.329
1981 Doolittle WF, Bonen L. Molecular Sequence Data Indicating An Endosymbiotic Origin For Plastids Annals of the New York Academy of Sciences. 361: 248-259. DOI: 10.1111/J.1749-6632.1981.Tb54368.X  0.332
1980 Dover G, Doolittle WF. Modes of genome evolution Nature. 288: 646-647. PMID 6256636 DOI: 10.1038/288646A0  0.318
1980 Doolittle WF, Sapienza C. Selfish genes, the phenotype paradigm and genome evolution. Nature. 284: 601-603. PMID 6245369 DOI: 10.1038/284601A0  0.405
1980 Hofman JD, Lau RH, Doolittle WF. The number, physical organization and transcription of ribosomal RNA cistrons in an archaebacterium: Halobacterium halobium. Nucleic Acids Research. 7: 1321-33. PMID 514815 DOI: 10.1093/Nar/7.5.1321  0.385
1980 Doolittle WF. The cyanobacterial genome, its expression, and the control of that expression. Advances in Microbial Physiology. 20: 1-102. PMID 119432 DOI: 10.1016/S0065-2911(08)60206-4  0.343
1978 Bonen L, Doolittle WF. Ribosomal RNA homologies and the evolution of the filamentous blue-green bacteria. Journal of Molecular Evolution. 10: 283-91. PMID 416225 DOI: 10.1007/Bf01734218  0.396
1978 Doolittle WF. Genes in pieces: were they ever together? Nature. 272: 581-582. DOI: 10.1038/272581A0  0.43
1971 Doolittle WF, Pace NR. Transcriptional organization of the ribosomal RNA cistrons in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 68: 1786-90. PMID 4942914 DOI: 10.1073/Pnas.68.8.1786  0.641
1970 Doolittle WF, Pace NR. Synthesis of 5S ribosomal RNA in Escherichia coli after rifampicin treatment. Nature. 228: 125-9. PMID 4918254  0.58
1968 Doolittle WF, Yanofsky C. Mutants of Escherichia coli with an altered tryptophanyl-transfer ribonucleic acid synthetase. Journal of Bacteriology. 95: 1283-94. PMID 4869215 DOI: 10.1128/Jb.95.4.1283-1294.1968  0.483
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