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Fred H. (Rusty) Gage - Publications

Affiliations: 
Salk Institute for Biological Studies, La Jolla, CA, United States 
 University of California, San Diego, La Jolla, CA 
Area:
Plasticity
Website:
http://logg.salk.edu/index.php
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Year Citation  Score
2024 Podvin S, Jones J, Kang A, Goodman R, Reed P, Lietz CB, Then J, Lee KC, Eyler LT, Jeste DV, Gage FH, Hook V. Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures. Molecular Psychiatry. PMID 38302561 DOI: 10.1038/s41380-024-02422-x  0.768
2023 Manole A, Wong T, Rhee A, Novak S, Chin SM, Tsimring K, Paucar A, Williams A, Newmeyer TF, Schafer ST, Rosh I, Kaushik S, Hoffman R, Chen S, Wang G, ... ... Gage FH, et al. NGLY1 mutations cause protein aggregation in human neurons. Cell Reports. 42: 113466. PMID 38039131 DOI: 10.1016/j.celrep.2023.113466  0.332
2023 Garrison MA, Jang Y, Bae T, Cherskov A, Emery SB, Fasching L, Jones A, Moldovan JB, Molitor C, Pochareddy S, Peters MA, Shin JH, Wang Y, Yang X, Akbarian S, ... ... Gage FH, et al. Genomic data resources of the Brain Somatic Mosaicism Network for neuropsychiatric diseases. Scientific Data. 10: 813. PMID 37985666 DOI: 10.1038/s41597-023-02645-7  0.507
2023 Traxler L, Lucciola R, Herdy JR, Jones JR, Mertens J, Gage FH. Neural cell state shifts and fate loss in ageing and age-related diseases. Nature Reviews. Neurology. PMID 37268723 DOI: 10.1038/s41582-023-00815-0  0.704
2023 Kempermann G, Song H, Gage FH. Adult neurogenesis in the hippocampus. Hippocampus. 33: 269-270. PMID 36912499 DOI: 10.1002/hipo.23525  0.638
2022 Wilson MN, Thunemann M, Liu X, Lu Y, Puppo F, Adams JW, Kim JH, Ramezani M, Pizzo DP, Djurovic S, Andreassen OA, Mansour AA, Gage FH, Muotri AR, Devor A, et al. Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex. Nature Communications. 13: 7945. PMID 36572698 DOI: 10.1038/s41467-022-35536-3  0.556
2022 Herdy JR, Traxler L, Agarwal RK, Karbacher L, Schlachetzki JCM, Boehnke L, Zangwill D, Galasko D, Glass CK, Mertens J, Gage FH. Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer's disease. Cell Stem Cell. 29: 1637-1652.e6. PMID 36459967 DOI: 10.1016/j.stem.2022.11.010  0.716
2022 van den Hurk M, Lau S, Marchetto MC, Mertens J, Stern S, Corti O, Brice A, Winner B, Winkler J, Gage FH, Bardy C. Druggable transcriptomic pathways revealed in Parkinson's patient-derived midbrain neurons. Npj Parkinson's Disease. 8: 134. PMID 36258029 DOI: 10.1038/s41531-022-00400-0  0.675
2022 Linker SB, Narvaiza I, Hsu JY, Wang M, Qiu F, Mendes APD, Oefner R, Kottilil K, Sharma A, Randolph-Moore L, Mejia E, Santos R, Marchetto MC, Gage FH. Human-specific regulation of neural maturation identified by cross-primate transcriptomics. Current Biology : Cb. PMID 36228612 DOI: 10.1016/j.cub.2022.09.028  0.82
2022 Pașca SP, Arlotta P, Bateup HS, Camp JG, Cappello S, Gage FH, Knoblich JA, Kriegstein AR, Lancaster MA, Ming GL, Muotri AR, Park IH, Reiner O, Song H, Studer L, et al. A nomenclature consensus for nervous system organoids and assembloids. Nature. 609: 907-910. PMID 36171373 DOI: 10.1038/s41586-022-05219-6  0.706
2022 Traxler L, Herdy JR, Stefanoni D, Eichhorner S, Pelucchi S, Szücs A, Santagostino A, Kim Y, Agarwal RK, Schlachetzki JCM, Glass CK, Lagerwall J, Galasko D, Gage FH, D'Alessandro A, et al. Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer's disease. Cell Metabolism. PMID 35987203 DOI: 10.1016/j.cmet.2022.07.014  0.676
2022 Bae T, Fasching L, Wang Y, Shin JH, Suvakov M, Jang Y, Norton S, Dias C, Mariani J, Jourdon A, Wu F, Panda A, Pattni R, Chahine Y, Yeh R, ... ... Gage FH, et al. Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability. Science (New York, N.Y.). 377: 511-517. PMID 35901164 DOI: 10.1126/science.abm6222  0.783
2022 van Niekerk EA, Kawaguchi R, Marques de Freria C, Groeniger K, Marchetto MC, Dupraz S, Bradke F, Geschwind DH, Gage FH, Tuszynski MH. Methods for culturing adult CNS neurons reveal a CNS conditioning effect. Cell Reports Methods. 2: 100255. PMID 35880023 DOI: 10.1016/j.crmeth.2022.100255  0.588
2022 Bermperidis T, Schafer S, Gage FH, Sejnowski T, Torres EB. Dynamic Interrogation of Stochastic Transcriptome Trajectories Using Disease Associated Genes Reveals Distinct Origins of Neurological and Psychiatric Disorders. Frontiers in Neuroscience. 16: 884707. PMID 35720720 DOI: 10.3389/fnins.2022.884707  0.424
2021 Heard KJ, Shokhirev MN, Becronis C, Fredlender C, Zahid N, Le AT, Ji Y, Skime M, Nelson T, Hall-Flavin D, Weinshilboum R, Gage FH, Vadodaria KC. Chronic cortisol differentially impacts stem cell-derived astrocytes from major depressive disorder patients. Translational Psychiatry. 11: 608. PMID 34848679 DOI: 10.1038/s41398-021-01733-9  0.798
2021 Johnston S, Parylak S, Kim S, Mac N, Lim C, Gallina I, Bloyd C, Newberry A, Saavedra CD, Novak O, Goncalves JT, Gage FH, Shtrahman M. AAV ablates neurogenesis in the adult murine hippocampus. Elife. 10. PMID 34259630 DOI: 10.7554/eLife.59291  0.312
2021 Dias GP, Murphy T, Stangl D, Ahmet S, Morisse B, Nix A, Aimone LJ, Aimone JB, Kuro-O M, Gage FH, Thuret S. Intermittent fasting enhances long-term memory consolidation, adult hippocampal neurogenesis, and expression of longevity gene Klotho. Molecular Psychiatry. PMID 34031536 DOI: 10.1038/s41380-021-01102-4  0.791
2021 Mertens J, Herdy JR, Traxler L, Schafer ST, Schlachetzki JCM, Böhnke L, Reid DA, Lee H, Zangwill D, Fernandes DP, Agarwal RK, Lucciola R, Zhou-Yang L, Karbacher L, Edenhofer F, ... ... Gage FH, et al. Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients. Cell Stem Cell. PMID 33910058 DOI: 10.1016/j.stem.2021.04.004  0.716
2021 Reid DA, Reed PJ, Schlachetzki JCM, Nitulescu II, Chou G, Tsui EC, Jones JR, Chandran S, Lu AT, McClain CA, Ooi JH, Wang TW, Lana AJ, Linker SB, Ricciardulli AS, ... ... Gage FH, et al. Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons. Science (New York, N.Y.). 372: 91-94. PMID 33795458 DOI: 10.1126/science.abb9032  0.781
2021 Nakatsuka N, Heard KJ, Faillétaz A, Momotenko D, Vörös J, Gage FH, Vadodaria KC. Sensing serotonin secreted from human serotonergic neurons using aptamer-modified nanopipettes. Molecular Psychiatry. PMID 33767349 DOI: 10.1038/s41380-021-01066-5  0.799
2021 Vadodaria KC, Mendes APD, Mei A, Racha V, Erikson G, Shokhirev MN, Oefner R, Heard KJ, McCarthy MJ, Eyler L, Kelsoe JR, Santos R, Marchetto MC, Gage FH. Altered Neuronal Support and Inflammatory Response in Bipolar Disorder Patient-Derived Astrocytes. Stem Cell Reports. PMID 33667413 DOI: 10.1016/j.stemcr.2021.02.004  0.807
2021 Fukuda S, Varshney A, Fowler BJ, Wang SB, Narendran S, Ambati K, Yasuma T, Magagnoli J, Leung H, Hirahara S, Nagasaka Y, Yasuma R, Apicella I, Pereira F, Makin RD, ... ... Gage FH, et al. Cytoplasmic synthesis of endogenous complementary DNA via reverse transcription and implications in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33526699 DOI: 10.1073/pnas.2022751118  0.671
2020 Bedrosian TA, Houtman J, Eguiguren JS, Ghassemzadeh S, Rund N, Novaresi NM, Hu L, Parylak SL, Denli AM, Randolph-Moore L, Namba T, Gage FH, Toda T. Lamin B1 decline underlies age-related loss of adult hippocampal neurogenesis. The Embo Journal. e105819. PMID 33300615 DOI: 10.15252/embj.2020105819  0.732
2020 Wang QW, Lu SY, Liu YN, Chen Y, Wei H, Shen W, Chen YF, Fu CL, Wang YH, Dai A, Huang X, Gage FH, Xu Q, Yao J. Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 33229564 DOI: 10.1073/pnas.2016416117  0.387
2020 Sun G, Chiuppesi F, Chen X, Wang C, Tian E, Nguyen J, Kha M, Trinh D, Zhang H, Marchetto MC, Song H, Ming GL, Gage FH, Diamond DJ, Wussow F, et al. Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids. Cell Reports. Medicine. 1: 100002. PMID 33205055 DOI: 10.1016/j.xcrm.2020.100002  0.605
2020 Figueiredo T, Mendes APD, Moreira DP, Goulart E, Oliveira D, Kobayashi GS, Stern S, Kok F, Marchetto MC, Santos R, Gage FH, Zatz M. Inositol monophosphatase 1 (IMPA1) mutation in intellectual disability patients impairs neurogenesis but not gliogenesis. Molecular Psychiatry. PMID 32839513 DOI: 10.1038/s41380-020-00862-9  0.351
2020 Kerman BE, Genoud S, Kurt Vatandaslar B, Denli AM, Ghosh SG, Xu X, Yeo GW, Aimone JB, Gage FH. Motoneuron expression profiling identifies an association between an axonal splice variant of HDGF-related protein 3 and peripheral myelination. The Journal of Biological Chemistry. PMID 32647008 DOI: 10.1074/Jbc.Ra120.014329  0.784
2020 Stern S, Sarkar A, Galor D, Stern T, Mei A, Stern Y, Mendes APD, Randolph-Moore L, Rouleau G, Bang AG, Santos R, Alda M, Marchetto MC, Gage FH. A Physiological Instability Displayed in Hippocampal Neurons Derived From Lithium-Nonresponsive Bipolar Disorder Patients. Biological Psychiatry. PMID 32278494 DOI: 10.1016/J.Biopsych.2020.01.020  0.525
2020 Shen W, Wang QW, Liu YN, Marchetto MC, Linker S, Lu SY, Chen Y, Liu C, Guo C, Xing Z, Shi W, Kelsoe JR, Alda M, Wang H, Zhong Y, ... ... Gage FH, et al. Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 32041882 DOI: 10.1073/Pnas.1918165117  0.361
2020 Kurian L, Sancho-Martinez I, Nivet E, Aguirre A, Moon K, Pendaries C, Volle-Challier C, Bono F, Herbert JM, Pulecio J, Xia Y, Li M, Montserrat N, Ruiz S, Dubova I, ... ... Gage FH, et al. Author Correction: Conversion of human fibroblasts to angioblast-like progenitor cells. Nature Methods. PMID 32034376 DOI: 10.1038/S41592-020-0745-8  0.71
2020 Sun G, Chiuppesi F, Chen X, Wang C, Tian E, Nguyen J, Kha M, Trinh D, Zhang H, Marchetto MC, Song H, Ming G, Gage FH, Diamond DJ, Wussow F, et al. Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids Cell Reports Medicine. 1: 100002. DOI: 10.1016/j.xcrm.2020.100002  0.432
2019 Stern S, Linker S, Vadodaria KC, Marchetto MC, Gage FH. Prediction of Response to Drug Therapy in Psychiatric Disorders. Focus (American Psychiatric Publishing). 17: 294-307. PMID 32015721 DOI: 10.1176/appi.focus.17304  0.757
2019 Zhu Z, Mesci P, Bernatchez JA, Gimple RC, Wang X, Schafer ST, Wettersten HI, Beck S, Clark AE, Wu Q, Prager BC, Kim LJY, Dhanwani R, Sharma S, Garancher A, ... ... Gage FH, et al. Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αβ Axis. Cell Stem Cell. PMID 31956038 DOI: 10.1016/J.Stem.2019.11.016  0.551
2019 Vadodaria KC, Jones JR, Linker S, Gage FH. Modeling Brain Disorders Using Induced Pluripotent Stem Cells. Cold Spring Harbor Perspectives in Biology. PMID 31767646 DOI: 10.1101/cshperspect.a035659  0.806
2019 Stern S, Sarkar A, Stern T, Mei A, Mendes APD, Stern Y, Goldberg G, Galor D, Nguyen T, Randolph-Moore L, Kim Y, Rouleau G, Bang A, Alda M, Santos R, ... ... Gage FH, et al. Mechanisms Underlying the Hyperexcitability of CA3 and Dentate Gyrus Hippocampal Neurons Derived From Patients With Bipolar Disorder. Biological Psychiatry. PMID 31732108 DOI: 10.1016/J.Biopsych.2019.09.018  0.496
2019 Nott A, Holtman IR, Coufal NG, Schlachetzki JCM, Yu M, Hu R, Han CZ, Pena M, Xiao J, Wu Y, Keulen Z, Pasillas MP, O'Connor C, Nickl CK, Schafer ST, ... ... Gage FH, et al. Brain cell type-specific enhancer-promoter interactome maps and disease risk association. Science (New York, N.Y.). PMID 31727856 DOI: 10.1126/Science.Aay0793  0.649
2019 van den Hurk M, Erwin JA, Yeo GW, Gage FH, Bardy C. Corrigendum: Patch-Seq Protocol to Analyze the Electrophysiology, Morphology and Transcriptome of Whole Single Neurons Derived From Human Pluripotent Stem Cells. Frontiers in Molecular Neuroscience. 12: 150. PMID 31244603 DOI: 10.3389/Fnmol.2019.00150  0.788
2019 Nudell V, Wei H, Nievergelt C, Maihofer AX, Shilling P, Alda M, Berrettini WH, Brennand KJ, Calabrese JR, Coryell WH, Covault JM, Frye MA, Gage F, Gershon E, McInnis MG, et al. Entrainment of Circadian Rhythms to Temperature Reveals Amplitude Deficits in Fibroblasts from Patients with Bipolar Disorder and Possible Links to Calcium Channels. Molecular Neuropsychiatry. 5: 115-124. PMID 31192224 DOI: 10.1159/000497354  0.506
2019 Sommer A, Marxreiter F, Krach F, Fadler T, Grosch J, Maroni M, Graef D, Eberhardt E, Riemenschneider MJ, Yeo GW, Kohl Z, Xiang W, Gage FH, Winkler J, Prots I, et al. Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease. Cell Stem Cell. 24: 1006. PMID 31173705 DOI: 10.1016/j.stem.2019.04.019  0.519
2019 Vadodaria KC, Ji Y, Skime M, Paquola A, Nelson T, Hall-Flavin D, Fredlender C, Heard KJ, Deng Y, Le AT, Dave S, Fung L, Li X, Marchetto MC, Weinshilboum R, ... Gage FH, et al. Studying treatment resistance in depression using patient derived neurons in vitro. Molecular Psychiatry. 24: 775. PMID 31118486 DOI: 10.1038/s41380-019-0424-2  0.79
2019 Herdy J, Schafer S, Kim Y, Ansari Z, Zangwill D, Ku M, Paquola A, Lee H, Mertens J, Gage FH. Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons. Elife. 8. PMID 31099332 DOI: 10.7554/Elife.41356  0.683
2019 Vadodaria KC, Ji Y, Skime M, Paquola AC, Nelson T, Hall-Flavin D, Heard KJ, Fredlender C, Deng Y, Elkins J, Dani K, Le AT, Marchetto MC, Weinshilboum R, Gage FH. Altered serotonergic circuitry in SSRI-resistant major depressive disorder patient-derived neurons. Molecular Psychiatry. PMID 30903001 DOI: 10.1038/s41380-019-0377-5  0.806
2019 Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, ... ... Gage FH, et al. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. PMID 30867594 DOI: 10.1038/S41586-019-1024-7  0.796
2019 Marchetto MC, Hrvoj-Mihic B, Kerman BE, Yu DX, Vadodaria KC, Linker SB, Narvaiza I, Santos R, Denli AM, Mendes AP, Oefner R, Cook J, McHenry L, Grasmick JM, Heard K, ... ... Gage FH, et al. Species-specific maturation profiles of human, chimpanzee and bonobo neural cells. Elife. 8. PMID 30730291 DOI: 10.7554/Elife.37527  0.826
2019 Vadodaria KC, Ji Y, Skime M, Paquola A, Nelson T, Hall-Flavin D, Fredlender C, Heard KJ, Deng Y, Le AT, Dave S, Fung L, Li X, Marchetto MC, Weinshilboum R, ... Gage FH, et al. Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons. Molecular Psychiatry. PMID 30700803 DOI: 10.1038/s41380-019-0363-y  0.812
2019 Eftekharzadeh B, Daigle JG, Kapinos LE, Coyne A, Schiantarelli J, Carlomagno Y, Cook C, Miller SJ, Dujardin S, Amaral AS, Grima JC, Bennett RE, Tepper K, DeTure M, Vanderburg CR, ... ... Gage FH, et al. Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease. Neuron. 101: 349. PMID 30653936 DOI: 10.1016/J.Neuron.2018.12.031  0.601
2019 Lucassen PJ, Toni N, Kempermann G, Frisen J, Gage FH, Swaab DF. Limits to human neurogenesis-really? Molecular Psychiatry. PMID 30617274 DOI: 10.1038/S41380-018-0337-5  0.692
2019 Schafer ST, Paquola ACM, Stern S, Gosselin D, Ku M, Pena M, Kuret TJM, Liyanage M, Mansour AA, Jaeger BN, Marchetto MC, Glass CK, Mertens J, Gage FH. Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons. Nature Neuroscience. PMID 30617258 DOI: 10.1038/S41593-018-0295-X  0.691
2019 Barr C, Feng Y, Wigg K, Getsinger J, Marchetto MC, Gage F. 26 FUNCTIONAL STUDIES OF PSYCHIATRIC RISK REGIONS USING CRISPR/CAS9 GENOME EDITED STEM CELL DERIVED NEURAL CELLS European Neuropsychopharmacology. 29: S73-S74. DOI: 10.1016/j.euroneuro.2019.07.167  0.347
2018 Padmanabhan K, Osakada F, Tarabrina A, Kizer E, Callaway EM, Gage FH, Sejnowski TJ. Centrifugal Inputs to the Main Olfactory Bulb Revealed Through Whole Brain Circuit-Mapping. Frontiers in Neuroanatomy. 12: 115. PMID 30666191 DOI: 10.3389/Fnana.2018.00115  0.705
2018 Kim Y, Vadodaria KC, Lenkei Z, Kato T, Gage FH, Marchetto MC, Santos R. MITOCHONDRIA, METABOLISM AND REDOX MECHANISMS IN PSYCHIATRIC DISORDERS. Antioxidants & Redox Signaling. PMID 30585734 DOI: 10.1089/ars.2018.7606  0.775
2018 Suh H, Zhou QG, Fernandez-Carasa I, Clemenson GD, Pons-Espinal M, Ro EJ, Marti M, Raya A, Gage FH, Consiglio A. Long-Term Labeling of Hippocampal Neural Stem Cells by a Lentiviral Vector. Frontiers in Molecular Neuroscience. 11: 415. PMID 30498432 DOI: 10.3389/Fnmol.2018.00415  0.807
2018 McCarthy MJ, Wei H, Nievergelt CM, Stautland A, Maihofer AX, Welsh DK, Shilling P, Alda M, Alliey-Rodriguez N, Anand A, Andreasson OA, Balaraman Y, Berrettini WH, Bertram H, Brennand KJ, ... ... Gage FH, et al. Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30487653 DOI: 10.1038/S41386-018-0273-8  0.507
2018 Kuhn HG, Toda T, Gage FH. Adult Hippocampal Neurogenesis: A Coming-of-Age Story. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 38: 10401-10410. PMID 30381404 DOI: 10.1523/JNEUROSCI.2144-18.2018  0.335
2018 Mertens J, Reid D, Lau S, Kim Y, Gage FH. Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases. Annual Review of Genetics. PMID 30208291 DOI: 10.1146/Annurev-Genet-120417-031534  0.685
2018 Choi SH, Bylykbashi E, Chatila ZK, Lee SW, Pulli B, Clemenson GD, Kim E, Rompala A, Oram MK, Asselin C, Aronson J, Zhang C, Miller SJ, Lesinski A, Chen JW, ... ... Gage FH, et al. Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model. Science (New York, N.Y.). 361. PMID 30190379 DOI: 10.1126/Science.Aan8821  0.788
2018 Eftekharzadeh B, Daigle JG, Kapinos LE, Coyne A, Schiantarelli J, Carlomagno Y, Cook C, Miller SJ, Dujardin S, Amaral AS, Grima JC, Bennett RE, Tepper K, DeTure M, Vanderburgh CR, ... ... Gage FH, et al. Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease. Neuron. 99: 925-940.e7. PMID 30189209 DOI: 10.1016/J.Neuron.2018.07.039  0.643
2018 van den Hurk M, Erwin JA, Yeo GW, Gage FH, Bardy C. Patch-Seq Protocol to Analyze the Electrophysiology, Morphology and Transcriptome of Whole Single Neurons Derived From Human Pluripotent Stem Cells. Frontiers in Molecular Neuroscience. 11: 261. PMID 30147644 DOI: 10.3389/Fnmol.2018.00261  0.81
2018 Jaeger BN, Linker SB, Parylak SL, Barron JJ, Gallina IS, Saavedra CD, Fitzpatrick C, Lim CK, Schafer ST, Lacar B, Jessberger S, Gage FH. A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons. Nature Communications. 9: 3084. PMID 30082781 DOI: 10.1038/S41467-018-05418-8  0.821
2018 Sommer A, Maxreiter F, Krach F, Fadler T, Grosch J, Maroni M, Graef D, Eberhardt E, Riemenschneider MJ, Yeo GW, Kohl Z, Xiang W, Gage FH, Winkler J, Prots I, et al. Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease. Cell Stem Cell. 23: 123-131.e6. PMID 29979986 DOI: 10.1016/J.Stem.2018.06.015  0.456
2018 Kronenberg ZN, Fiddes IT, Gordon D, Murali S, Cantsilieris S, Meyerson OS, Underwood JG, Nelson BJ, Chaisson MJP, Dougherty ML, Munson KM, Hastie AR, Diekhans M, Hormozdiari F, Lorusso N, ... ... Gage FH, et al. High-resolution comparative analysis of great ape genomes. Science (New York, N.Y.). 360. PMID 29880660 DOI: 10.1126/Science.Aar6343  0.699
2018 Kim Y, Zheng X, Ansari Z, Bunnell MC, Herdy JR, Traxler L, Lee H, Paquola ACM, Blithikioti C, Ku M, Schlachetzki JCM, Winkler J, Edenhofer F, Glass CK, Paucar AA, ... ... Gage FH, et al. Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile. Cell Reports. 23: 2550-2558. PMID 29847787 DOI: 10.1016/J.Celrep.2018.04.105  0.662
2018 Stern S, Linker S, Vadodaria KC, Marchetto MC, Gage FH. Prediction of response to drug therapy in psychiatric disorders. Open Biology. 8. PMID 29794033 DOI: 10.1098/rsob.180031  0.771
2018 Strnadel J, Carromeu C, Bardy C, Navarro M, Platoshyn O, Glud AN, Marsala S, Kafka J, Miyanohara A, Kato T, Tadokoro T, Hefferan MP, Kamizato K, Yoshizumi T, Juhas S, ... ... Gage FH, et al. Survival of syngeneic and allogeneic iPSC-derived neural precursors after spinal grafting in minipigs. Science Translational Medicine. 10. PMID 29743351 DOI: 10.1126/Scitranslmed.Aam6651  0.549
2018 Sarkar A, Mei A, Paquola ACM, Stern S, Bardy C, Klug JR, Kim S, Neshat N, Kim HJ, Ku M, Shokhirev MN, Adamowicz DH, Marchetto MC, Jappelli R, Erwin JA, ... ... Gage FH, et al. Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro. Cell Stem Cell. 22: 684-697.e9. PMID 29727680 DOI: 10.1016/J.Stem.2018.04.009  0.822
2018 Erwin JA, Paquola ACM, Singer T, Gallina I, Novotny M, Quayle C, Bedrosian TA, Alves FIA, Butcher CR, Herdy JR, Sarkar A, Lasken RS, Muotri AR, Gage FH. Author Correction: L1-associated genomic regions are deleted in somatic cells of the healthy human brain. Nature Neuroscience. PMID 29703932 DOI: 10.1038/S41593-018-0131-3  0.776
2018 Kempermann G, Gage FH, Aigner L, Song H, Curtis MA, Thuret S, Kuhn HG, Jessberger S, Frankland PW, Cameron HA, Gould E, Hen R, Abrous DN, Toni N, Schinder AF, et al. Human Adult Neurogenesis: Evidence and Remaining Questions. Cell Stem Cell. PMID 29681514 DOI: 10.1016/J.Stem.2018.04.004  0.817
2018 Toda T, Parylak SL, Linker SB, Gage FH. The role of adult hippocampal neurogenesis in brain health and disease. Molecular Psychiatry. PMID 29679070 DOI: 10.1038/s41380-018-0036-2  0.333
2018 Zheng Y, Shen W, Zhang J, Yang B, Liu YN, Qi H, Yu X, Lu SY, Chen Y, Xu YZ, Li Y, Gage FH, Mi S, Yao J. CRISPR interference-based specific and efficient gene inactivation in the brain. Nature Neuroscience. PMID 29403034 DOI: 10.1038/S41593-018-0077-5  0.421
2018 Vadodaria KC, Amatya DN, Marchetto MC, Gage FH. Modeling psychiatric disorders using patient stem cell-derived neurons: a way forward. Genome Medicine. 10: 1. PMID 29301565 DOI: 10.1186/s13073-017-0512-3  0.81
2018 Stern S, Marchetto MC, Santos R, Wang M, Bang A, Alda M, Gage F. 265. Electrophysiological Measurements of DG Neurons Derived From Bipolar Disorder and Schizophrenia Patients Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.284  0.313
2017 Paquola ACM, Erwin JA, Gage FH. Insights into the role of somatic mosaicism in the brain. Current Opinion in Systems Biology. 1: 90-94. PMID 29226270 DOI: 10.1016/J.Coisb.2016.12.004  0.709
2017 Toda T, Gage FH. Review: adult neurogenesis contributes to hippocampal plasticity. Cell and Tissue Research. PMID 29185071 DOI: 10.1007/s00441-017-2735-4  0.327
2017 Jaeger BN, Parylak SL, Gage FH. Mechanisms of dietary flavonoid action in neuronal function and neuroinflammation. Molecular Aspects of Medicine. PMID 29117513 DOI: 10.1016/j.mam.2017.11.003  0.304
2017 Erwin JA, Paquola ACM, Singer T, Gallina I, Novotny M, Quayle C, Bedrosian TA, Alves FIA, Butcher CR, Herdy JR, Sarkar A, Lasken RS, Muotri AR, Gage FH. Corrigendum: L1-associated genomic regions are deleted in somatic cells of the healthy human brain. Nature Neuroscience. 20: 1427. PMID 28949329 DOI: 10.1038/Nn1017-1427A  0.776
2017 Toda T, Hsu JY, Linker SB, Hu L, Schafer ST, Mertens J, Jacinto FV, Hetzer MW, Gage FH. Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells. Cell Stem Cell. PMID 28919367 DOI: 10.1016/J.Stem.2017.08.012  0.687
2017 Topol A, Zhu S, Hartley BJ, English J, Hauberg ME, Tran N, Rittenhouse CA, Simone A, Ruderfer DM, Johnson J, Readhead B, Hadas Y, Gochman PA, Wang YC, Shah H, ... ... Gage FH, et al. Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells. Cell Reports. 20: 2525. PMID 28877483 DOI: 10.1016/J.Celrep.2017.08.073  0.521
2017 Vadodaria KC, Stern S, Marchetto MC, Gage FH. Serotonin in psychiatry: in vitro disease modeling using patient-derived neurons. Cell and Tissue Research. PMID 28812143 DOI: 10.1007/s00441-017-2670-4  0.817
2017 Linker SB, Marchetto MC, Narvaiza I, Denli AM, Gage FH. Examining non-LTR retrotransposons in the context of the evolving primate brain. Bmc Biology. 15: 68. PMID 28800766 DOI: 10.1186/S12915-017-0409-Z  0.783
2017 Newkirk SJ, Lee S, Grandi FC, Gaysinskaya V, Rosser JM, Vanden Berg N, Hogarth CA, Marchetto MCN, Muotri AR, Griswold MD, Ye P, Bortvin A, Gage FH, Boeke JD, An W. Intact piRNA pathway prevents L1 mobilization in male meiosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630288 DOI: 10.1073/Pnas.1701069114  0.511
2017 Santos R, Vadodaria KC, Jaeger BN, Mei A, Lefcochilos-Fogelquist S, Mendes APD, Erikson G, Shokhirev M, Randolph-Moore L, Fredlender C, Dave S, Oefner R, Fitzpatrick C, Pena M, Barron JJ, ... ... Gage FH, et al. Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells. Stem Cell Reports. 8: 1757-1769. PMID 28591655 DOI: 10.1016/J.Stemcr.2017.05.011  0.81
2017 Gosselin D, Skola D, Coufal NG, Holtman IR, Schlachetzki JCM, Sajti E, Jaeger BN, O'Connor C, Fitzpatrick C, Pasillas MP, Pena M, Adair A, Gonda DG, Levy ML, Ransohoff RM, ... Gage FH, et al. An environment-dependent transcriptional network specifies human microglia identity. Science (New York, N.Y.). PMID 28546318 DOI: 10.1126/Science.Aal3222  0.653
2017 Franks TM, Benner C, Narvaiza I, Marchetto MCN, Young JM, Malik HS, Gage FH, Hetzer MW. Corrigendum: Evolution of a transcriptional regulator from a transmembrane nucleoporin. Genes & Development. 31: 845. PMID 28512238 DOI: 10.1101/Gad.300699.117  0.767
2017 Ishii S, Torii M, Son AI, Rajendraprasad M, Morozov YM, Kawasawa YI, Salzberg AC, Fujimoto M, Brennand K, Nakai A, Mezger V, Gage FH, Rakic P, Hashimoto-Torii K. Variations in brain defects result from cellular mosaicism in the activation of heat shock signalling. Nature Communications. 8: 15157. PMID 28462912 DOI: 10.1038/Ncomms15157  0.654
2017 McConnell MJ, Moran JV, Abyzov A, Akbarian S, Bae T, Cortes-Ciriano I, Erwin JA, Fasching L, Flasch DA, Freed D, Ganz J, Jaffe AE, Kwan KY, Kwon M, Lodato MA, ... ... Gage FH, et al. Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network. Science (New York, N.Y.). 356. PMID 28450582 DOI: 10.1126/Science.Aal1641  0.797
2017 Lacar B, Linker SB, Jaeger BN, Krishnaswami SR, Barron JJ, Kelder MJ, Parylak SL, Paquola AC, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin JA, Hsu JY, Husband D, ... ... Gage FH, et al. Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nature Communications. 8: 15047. PMID 28303884 DOI: 10.1038/ncomms15047  0.794
2017 Stern S, Santos R, Marchetto MC, Mendes AP, Rouleau GA, Biesmans S, Wang QW, Yao J, Charnay P, Bang AG, Alda M, Gage FH. Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients' responsiveness to lithium. Molecular Psychiatry. PMID 28242870 DOI: 10.1038/Mp.2016.260  0.468
2017 Kelsoe J, Alda M, Berrettini W, Calabrese J, Coryell W, Craig D, Frye M, Gage F, Gershon E, McInnis M, Nievergelt C, Nurnberger J, Oedegaard K, Shilling P, Zandi P. The Pharmacogenomics of Bipolar Disorder Study: A Combined Analysis Of Ips Neuronal Expression And Gwas Data Identifies Cbarp And Card19 As Associated With Lithium Response European Neuropsychopharmacology. 27: S485-S486. DOI: 10.1016/J.Euroneuro.2016.09.575  0.336
2017 Gage F, Stern S, Santos R, Carol Marchetto M, Diniz Mendes A, Rouleau G, Biesmans S, Wang Q, Yao J, Charnay P, Bang A, Alda M. 715. Neurons from Bipolar Disorder Patients Are Characterized by Intrinsically Different Sub Populations of Neurons Biological Psychiatry. 81: S290. DOI: 10.1016/J.Biopsych.2017.02.782  0.49
2017 Kelsoe J, McCarthy M, Nievergelt C, Shilling P, Nurnberger J, Gershon E, Coryell W, McInnis M, Berrettini W, Odegaard K, Calabrese J, Zandi P, Alda M, Frye M, Craig D, ... ... Gage F, et al. 705. Using iPS Derived Neurons and GWAS Together to Identify Genes for Lithium Response Biological Psychiatry. 81: S285-S286. DOI: 10.1016/J.Biopsych.2017.02.772  0.78
2016 Gonçalves JT, Schafer ST, Gage FH. Adult Neurogenesis in the Hippocampus: From Stem Cells to Behavior. Cell. 167: 897-914. PMID 27814520 DOI: 10.1016/j.cell.2016.10.021  0.401
2016 Vadodaria KC, Marchetto MC, Mertens J, Gage FH. Generating human serotonergic neurons in vitro: Methodological advances. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 27716980 DOI: 10.1002/Bies.201600127  0.827
2016 Erwin JA, Paquola AC, Singer T, Gallina I, Novotny M, Quayle C, Bedrosian TA, Alves FI, Butcher CR, Herdy JR, Sarkar A, Lasken RS, Muotri AR, Gage FH. L1-associated genomic regions are deleted in somatic cells of the healthy human brain. Nature Neuroscience. PMID 27618310 DOI: 10.1038/Nn.4388  0.787
2016 Du H, Deng W, Aimone JB, Ge M, Parylak S, Walch K, Zhang W, Cook J, Song H, Wang L, Gage FH, Mu Y. Dopaminergic inputs in the dentate gyrus direct the choice of memory encoding. Proceedings of the National Academy of Sciences of the United States of America. PMID 27573822 DOI: 10.1073/Pnas.1606951113  0.755
2016 Chailangkarn T, Trujillo CA, Freitas BC, Hrvoj-Mihic B, Herai RH, Yu DX, Brown TT, Marchetto MC, Bardy C, McHenry L, Stefanacci L, Järvinen A, Searcy YM, DeWitt M, Wong W, ... ... Gage FH, et al. A human neurodevelopmental model for Williams syndrome. Nature. PMID 27509850 DOI: 10.1038/Nature19067  0.603
2016 Nuttle X, Giannuzzi G, Duyzend MH, Schraiber JG, Narvaiza I, Sudmant PH, Penn O, Chiatante G, Malig M, Huddleston J, Benner C, Camponeschi F, Ciofi-Baffoni S, Stessman HA, Marchetto MC, ... ... Gage FH, et al. Emergence of a Homo sapiens-specific gene family and chromosome 16p11.2 CNV susceptibility. Nature. PMID 27487209 DOI: 10.1038/Nature19075  0.783
2016 Padmanabhan K, Osakada F, Tarabrina A, Kizer E, Callaway EM, Gage FH, Sejnowski TJ. Diverse Representations of Olfactory Information in Centrifugal Feedback Projections. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7535-45. PMID 27413162 DOI: 10.1523/Jneurosci.3358-15.2016  0.696
2016 Han J, Kim HJ, Schafer ST, Paquola A, Clemenson GD, Toda T, Oh J, Pankonin AR, Lee BS, Johnston ST, Sarkar A, Denli AM, Gage FH. Functional Implications of miR-19 in the Migration of Newborn Neurons in the Adult Brain. Neuron. 91: 79-89. PMID 27387650 DOI: 10.1016/J.Neuron.2016.05.034  0.804
2016 Marchetto MC, Belinson H, Tian Y, Freitas BC, Fu C, Vadodaria KC, Beltrao-Braga PC, Trujillo CA, Mendes AP, Padmanabhan K, Nunez Y, Ou J, Ghosh H, Wright R, Brennand KJ, ... ... Gage FH, et al. Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. Molecular Psychiatry. PMID 27378147 DOI: 10.1038/Mp.2016.95  0.823
2016 Lacar B, Linker SB, Jaeger BN, Krishnaswami SR, Barron JJ, Kelder MJ, Parylak SL, Paquola AC, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin JA, Hsu JY, Husband D, ... ... Gage FH, et al. Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nature Communications. 7: 12020. PMID 27295945 DOI: 10.1038/Ncomms12020  0.778
2016 Zheng X, Boyer L, Jin M, Mertens J, Kim Y, Ma L, Ma L, Hamm M, Gage FH, Hunter T. Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation. Elife. 5. PMID 27282387 DOI: 10.7554/Elife.13374  0.706
2016 Franks TM, Benner C, Narvaiza I, Marchetto MC, Young JM, Malik HS, Gage FH, Hetzer MW. Evolution of a transcriptional regulator from a transmembrane nucleoporin. Genes & Development. PMID 27198230 DOI: 10.1101/Gad.280941.116  0.786
2016 Poo MM, Pignatelli M, Ryan TJ, Tonegawa S, Bonhoeffer T, Martin KC, Rudenko A, Tsai LH, Tsien RW, Fishell G, Mullins C, Gonçalves JT, Shtrahman M, Johnston ST, Gage FH, et al. What is memory? The present state of the engram. Bmc Biology. 14: 40. PMID 27197636 DOI: 10.1186/S12915-016-0261-6  0.575
2016 Mertens J, Marchetto MC, Bardy C, Gage FH. Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience. Nature Reviews. Neuroscience. PMID 27194476 DOI: 10.1038/Nrn.2016.46  0.711
2016 Oedegaard KJ, Alda M, Anand A, Andreassen OA, Balaraman Y, Berrettini WH, Bhattacharjee A, Brennand KJ, Burdick KE, Calabrese JR, Calkin CV, Claasen A, Coryell WH, Craig D, DeModena A, ... ... Gage FH, et al. The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample. Bmc Psychiatry. 16: 129. PMID 27150464 DOI: 10.1186/S12888-016-0732-X  0.737
2016 Topol A, Zhu S, Hartley BJ, English J, Hauberg ME, Tran N, Rittenhouse CA, Simone A, Ruderfer DM, Johnson J, Readhead B, Hadas Y, Gochman PA, Wang YC, Shah H, ... ... Gage FH, et al. Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells. Cell Reports. PMID 27117414 DOI: 10.1016/J.Celrep.2016.03.090  0.507
2016 Lacar B, Linker SB, Jaeger BN, Krishnaswami S, Barron J, Kelder M, Parylak S, Paquola A, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin J, Hsu JY, Husband D, ... ... Gage FH, et al. Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nature Communications. 7: 11022. PMID 27090946 DOI: 10.1038/Ncomms11022  0.825
2016 Harrison BJ, Venkat G, Lamb JL, Hutson TH, Drury C, Rau KK, Bunge MB, Mendell LM, Gage FH, Johnson RD, Hill CE, Rouchka EC, Moon LD, Petruska JC. The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 4259-75. PMID 27076424 DOI: 10.1523/Jneurosci.2423-15.2016  0.576
2016 Ettle B, Kerman BE, Valera E, Gillmann C, Schlachetzki JC, Reiprich S, Büttner C, Ekici AB, Reis A, Wegner M, Bäuerle T, Riemenschneider MJ, Masliah E, Gage FH, Winkler J. α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy. Acta Neuropathologica. PMID 27059609 DOI: 10.1007/S00401-016-1572-Y  0.697
2016 Krishnaswami SR, Grindberg RV, Novotny M, Venepally P, Lacar B, Bhutani K, Linker SB, Pham S, Erwin JA, Miller JA, Hodge R, McCarthy JK, Kelder M, McCorrison J, Aevermann BD, ... ... Gage FH, et al. Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons. Nature Protocols. 11: 499-524. PMID 26890679 DOI: 10.1038/Nprot.2016.015  0.79
2016 Tang X, Kim J, Zhou L, Wengert E, Zhang L, Wu Z, Carromeu C, Muotri AR, Marchetto MC, Gage FH, Chen G. KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome. Proceedings of the National Academy of Sciences of the United States of America. PMID 26733678 DOI: 10.1073/Pnas.1524013113  0.66
2016 Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, Koch P, Gage FH. The different moods of human serotonergic neurons. Molecular Psychiatry. 21: 3. PMID 26678308 DOI: 10.1038/Mp.2015.202  0.813
2015 Sarkar A, Marchetto MC, Gage FH. Synaptic activity: an emerging player in schizophrenia. Brain Research. PMID 26723567 DOI: 10.1016/J.Brainres.2015.12.028  0.507
2015 Harrison BJ, Venkat G, Hutson T, Rau KK, Bunge MB, Mendell LM, Gage FH, Johnson RD, Hill C, Rouchka EC, Moon L, Petruska JC. Transcriptional changes in sensory ganglia associated with primary afferent axon collateral sprouting in spared dermatome model. Genomics Data. 6: 249-52. PMID 26697387 DOI: 10.1016/J.Gdata.2015.10.005  0.577
2015 Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, ... ... Gage FH, et al. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports. PMID 26610635 DOI: 10.1016/J.Stemcr.2015.10.011  0.779
2015 Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, ... ... Gage FH, et al. Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder. Nature. PMID 26605530 DOI: 10.1038/Nature16182  0.777
2015 Johnston ST, Shtrahman M, Parylak S, Gonçalves JT, Gage FH. Paradox of Pattern Separation and Adult Neurogenesis: A Dual Role for New Neurons Balancing Memory Resolution and Robustness. Neurobiology of Learning and Memory. PMID 26549627 DOI: 10.1016/J.Nlm.2015.10.013  0.304
2015 Kim HJ, Denli AM, Wright R, Baul TD, Clemenson GD, Morcos AS, Zhao C, Schafer ST, Gage FH, Kagalwala MN. REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 14872-84. PMID 26538656 DOI: 10.1523/Jneurosci.4286-14.2015  0.831
2015 Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, ... ... Gage FH, et al. Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder. Nature. PMID 26524527 DOI: 10.1038/Nature15526  0.777
2015 Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, Koch P, Gage FH. Generation of functional human serotonergic neurons from fibroblasts. Molecular Psychiatry. PMID 26503761 DOI: 10.1038/Mp.2015.161  0.831
2015 Denli AM, Narvaiza I, Kerman BE, Pena M, Benner C, Marchetto MC, Diedrich JK, Aslanian A, Ma J, Moresco JJ, Moore L, Hunter T, Saghatelian A, Gage FH. Primate-Specific ORF0 Contributes to Retrotransposon-Mediated Diversity. Cell. 163: 583-93. PMID 26496605 DOI: 10.1016/J.Cell.2015.09.025  0.783
2015 Mu Y, Zhao C, Toni N, Yao J, Gage FH. Distinct roles of NMDA receptors at different stages of granule cell development in the adult brain. Elife. 4. PMID 26473971 DOI: 10.7554/Elife.07871  0.748
2015 Mertens J, Paquola AC, Ku M, Hatch E, Böhnke L, Ladjevardi S, McGrath S, Campbell B, Lee H, Herdy JR, Gonçalves JT, Toda T, Kim Y, Winkler J, Yao J, ... ... Gage FH, et al. Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects. Cell Stem Cell. PMID 26456686 DOI: 10.1016/J.Stem.2015.09.001  0.716
2015 Tashiro A, Zhao C, Suh H, Gage FH. Preparation and Use of Retroviral Vectors for Labeling, Imaging, and Genetically Manipulating Cells. Cold Spring Harbor Protocols. 2015: pdb.top086363. PMID 26430260 DOI: 10.1101/Pdb.Top086363  0.696
2015 Tashiro A, Zhao C, Suh H, Gage FH. Analysis of Spine Motility of Newborn Granule Cells in Acute Brain Slices. Cold Spring Harbor Protocols. 2015: pdb.prot086397. PMID 26430257 DOI: 10.1101/Pdb.Prot086397  0.72
2015 Tashiro A, Zhao C, Suh H, Gage FH. Imaging Newborn Granule Cells in Fixed Sections. Cold Spring Harbor Protocols. 2015: pdb.prot086389. PMID 26430256 DOI: 10.1101/Pdb.Prot086389  0.707
2015 Tashiro A, Zhao C, Suh H, Gage FH. Purification and Injection of Retroviral Vectors. Cold Spring Harbor Protocols. 2015: pdb.prot086371. PMID 26430255 DOI: 10.1101/Pdb.Prot086371  0.706
2015 Prescott SL, Srinivasan R, Marchetto MC, Grishina I, Narvaiza I, Selleri L, Gage FH, Swigut T, Wysocka J. Enhancer Divergence and cis-Regulatory Evolution in the Human and Chimp Neural Crest. Cell. 163: 68-83. PMID 26365491 DOI: 10.1016/J.Cell.2015.08.036  0.793
2015 Kempermann G, Song H, Gage FH. Neurogenesis in the Adult Hippocampus. Cold Spring Harbor Perspectives in Biology. 7. PMID 26330519 DOI: 10.1101/cshperspect.a018812  0.694
2015 Jovičić A, Mertens J, Boeynaems S, Bogaert E, Chai N, Yamada SB, Paul JW, Sun S, Herdy JR, Bieri G, Kramer NJ, Gage FH, Van Den Bosch L, Robberecht W, Gitler AD. Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS. Nature Neuroscience. 18: 1226-9. PMID 26308983 DOI: 10.1038/Nn.4085  0.63
2015 Zhao C, Jou J, Wolff LJ, Sun H, Gage FH. Spine morphogenesis in newborn granule cells is differentially regulated in the outer and middle molecular layers. The Journal of Comparative Neurology. 523: 1588. PMID 26109421 DOI: 10.1002/Cne.23800  0.456
2015 Han J, Sarkar A, Gage FH. MIR137: big impacts from small changes. Nature Neuroscience. 18: 931-3. PMID 26108719 DOI: 10.1038/Nn.4045  0.416
2015 Kerman BE, Kim HJ, Padmanabhan K, Mei A, Georges S, Joens MS, Fitzpatrick JA, Jappelli R, Chandross KJ, August P, Gage FH. In vitro myelin formation using embryonic stem cells. Development (Cambridge, England). 142: 2213-25. PMID 26015546 DOI: 10.1242/Dev.116517  0.798
2015 Bardy C, van den Hurk M, Eames T, Marchand C, Hernandez RV, Kellogg M, Gorris M, Galet B, Palomares V, Brown J, Bang AG, Mertens J, Böhnke L, Boyer L, Simon S, ... Gage FH, et al. Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro. Proceedings of the National Academy of Sciences of the United States of America. 112: E2725-34. PMID 25870293 DOI: 10.1073/Pnas.1504393112  0.716
2015 Adamowicz DH, Mertens J, Gage FH. Alzheimer's disease: distinct stages in neurogenic decline? Biological Psychiatry. 77: 680-2. PMID 25835286 DOI: 10.1016/J.Biopsych.2015.02.021  0.675
2015 Amador-Arjona A, Cimadamore F, Huang CT, Wright R, Lewis S, Gage FH, Terskikh AV. SOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: E1936-45. PMID 25825708 DOI: 10.1073/pnas.1421480112  0.35
2015 Deng W, Gage FH. The effect of immature adult-born dentate granule cells on hyponeophagial behavior is related to their roles in learning and memory. Frontiers in Systems Neuroscience. 9: 34. PMID 25798094 DOI: 10.3389/Fnsys.2015.00034  0.319
2015 Clemenson GD, Lee SW, Deng W, Barrera VR, Iwamoto KS, Fanselow MS, Gage FH. Enrichment rescues contextual discrimination deficit associated with immediate shock. Hippocampus. 25: 385-92. PMID 25330953 DOI: 10.1002/Hipo.22380  0.821
2015 Krzisch M, Temprana SG, Mongiat LA, Armida J, Schmutz V, Virtanen MA, Kocher-Braissant J, Kraftsik R, Vutskits L, Conzelmann KK, Bergami M, Gage FH, Schinder AF, Toni N. Pre-existing astrocytes form functional perisynaptic processes on neurons generated in the adult hippocampus. Brain Structure & Function. 220: 2027-42. PMID 24748560 DOI: 10.1007/S00429-014-0768-Y  0.818
2015 Brennand K, Savas JN, Kim Y, Tran N, Simone A, Hashimoto-Torii K, Beaumont KG, Kim HJ, Topol A, Ladran I, Abdelrahim M, Matikainen-Ankney B, Chao SH, Mrksich M, Rakic P, ... ... Gage FH, et al. Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia. Molecular Psychiatry. 20: 361-8. PMID 24686136 DOI: 10.1038/Mp.2014.22  0.706
2015 Kempermann G, Song H, Gage FH. Neurogenesis in the adult hippocampus Cold Spring Harbor Perspectives in Biology. 7. DOI: 10.1101/cshperspect.a018812  0.638
2015 Jovičič A, Mertens J, Boeynaems S, Bogaert E, Chai N, Yamada SB, Paul JW, Sun S, Herdy JR, Bieri G, Kramer NJ, Gage FH, Van Den Bosch L, Robberecht W, Gitler AD. Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS Nature Neuroscience. 18: 1226-1229. DOI: 10.1038/nn.4085  0.599
2015 Han J, Sarkar A, Gage FH. MIR137: Big impacts from small changes Nature Neuroscience. 18: 931-933. DOI: 10.1038/nn.4045  0.374
2015 Clemenson GD, Deng W, Gage FH. Environmental enrichment and neurogenesis: From mice to humans Current Opinion in Behavioral Sciences. 4: 56-62. DOI: 10.1016/J.Cobeha.2015.02.005  0.75
2014 Hook V, Brennand KJ, Kim Y, Toneff T, Funkelstein L, Lee KC, Ziegler M, Gage FH. Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons. Stem Cell Reports. 3: 531-8. PMID 25358781 DOI: 10.1016/J.Stemcr.2014.08.001  0.628
2014 Aimone JB, Li Y, Lee SW, Clemenson GD, Deng W, Gage FH. Regulation and function of adult neurogenesis: from genes to cognition. Physiological Reviews. 94: 991-1026. PMID 25287858 DOI: 10.1152/Physrev.00004.2014  0.824
2014 Jessberger S, Gage FH. Adult neurogenesis: bridging the gap between mice and humans. Trends in Cell Biology. 24: 558-63. PMID 25124338 DOI: 10.1016/J.Tcb.2014.07.003  0.781
2014 Kim SH, Steele JW, Lee SW, Clemenson GD, Carter TA, Treuner K, Gadient R, Wedel P, Glabe C, Barlow C, Ehrlich ME, Gage FH, Gandy S. Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse. Molecular Psychiatry. 19: 1235-42. PMID 25113378 DOI: 10.1038/Mp.2014.87  0.773
2014 Erwin JA, Marchetto MC, Gage FH. Mobile DNA elements in the generation of diversity and complexity in the brain. Nature Reviews. Neuroscience. 15: 497-506. PMID 25005482 DOI: 10.1038/Nrn3730  0.694
2014 Stein JL, de la Torre-Ubieta L, Tian Y, Parikshak NN, Hernández IA, Marchetto MC, Baker DK, Lu D, Hinman CR, Lowe JK, Wexler EM, Muotri AR, Gage FH, Kosik KS, Geschwind DH. A quantitative framework to evaluate modeling of cortical development by neural stem cells. Neuron. 83: 69-86. PMID 24991955 DOI: 10.1016/J.Neuron.2014.05.035  0.756
2014 Yu DX, Marchetto MC, Gage FH. How to make a hippocampal dentate gyrus granule neuron. Development (Cambridge, England). 141: 2366-75. PMID 24917496 DOI: 10.1242/dev.096776  0.373
2014 Bekinschtein P, Kent BA, Oomen CA, Clemenson GD, Gage FH, Saksida LM, Bussey TJ. Brain-derived neurotrophic factor interacts with adult-born immature cells in the dentate gyrus during consolidation of overlapping memories. Hippocampus. 24: 905-11. PMID 24825389 DOI: 10.1002/Hipo.22304  0.729
2014 Hashimoto-Torii K, Torii M, Fujimoto M, Nakai A, El Fatimy R, Mezger V, Ju MJ, Ishii S, Chao SH, Brennand KJ, Gage FH, Rakic P. Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders. Neuron. 82: 560-72. PMID 24726381 DOI: 10.1016/J.Neuron.2014.03.002  0.683
2014 Yu DX, Di Giorgio FP, Yao J, Marchetto MC, Brennand K, Wright R, Mei A, McHenry L, Lisuk D, Grasmick JM, Silberman P, Silberman G, Jappelli R, Gage FH. Modeling hippocampal neurogenesis using human pluripotent stem cells. Stem Cell Reports. 2: 295-310. PMID 24672753 DOI: 10.1016/J.Stemcr.2014.01.009  0.716
2014 Pao GM, Zhu Q, Perez-Garcia CG, Chou SJ, Suh H, Gage FH, O'Leary DD, Verma IM. Role of BRCA1 in brain development. Proceedings of the National Academy of Sciences of the United States of America. 111: E1240-8. PMID 24639535 DOI: 10.1073/Pnas.1400783111  0.572
2014 Zhao C, Jou J, Wolff LJ, Sun H, Gage FH. Spine morphogenesis in newborn granule cells is differentially regulated in the outer and middle molecular layers. The Journal of Comparative Neurology. 522: 2756-66. PMID 24610721 DOI: 10.1002/Cne.23581  0.455
2014 Lacar B, Parylak SL, Vadodaria KC, Sarkar A, Gage FH. Increasing the resolution of the adult neurogenesis picture. F1000prime Reports. 6: 8. PMID 24592320 DOI: 10.12703/P6-8  0.831
2014 Crotti A, Benner C, Kerman BE, Gosselin D, Lagier-Tourenne C, Zuccato C, Cattaneo E, Gage FH, Cleveland DW, Glass CK. Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors. Nature Neuroscience. 17: 513-21. PMID 24584051 DOI: 10.1038/Nn.3668  0.742
2014 Vadodaria KC, Gage FH. SnapShot: adult hippocampal neurogenesis. Cell. 156: 1114-1114.e1. PMID 24581504 DOI: 10.1016/j.cell.2014.02.029  0.804
2014 Havlicek S, Kohl Z, Mishra HK, Prots I, Eberhardt E, Denguir N, Wend H, Plötz S, Boyer L, Marchetto MC, Aigner S, Sticht H, Groemer TW, Hehr U, Lampert A, ... ... Gage FH, et al. Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons. Human Molecular Genetics. 23: 2527-41. PMID 24381312 DOI: 10.1093/Hmg/Ddt644  0.32
2014 Hrvoj-Mihic B, Marchetto MC, Gage FH, Semendeferi K, Muotri AR. Novel tools, classic techniques: evolutionary studies using primate pluripotent stem cells. Biological Psychiatry. 75: 929-35. PMID 24041506 DOI: 10.1016/J.Biopsych.2013.08.007  0.614
2014 Aimone JB, Deng W, Gage FH. Adult neurogenesis in the dentate gyrus Space, Time and Memory in the Hippocampal Formation. 409-429. DOI: 10.1007/978-3-7091-1292-2_15  0.788
2013 Grindberg RV, Yee-Greenbaum JL, McConnell MJ, Novotny M, O'Shaughnessy AL, Lambert GM, Araúzo-Bravo MJ, Lee J, Fishman M, Robbins GE, Lin X, Venepally P, Badger JH, Galbraith DW, Gage FH, et al. RNA-sequencing from single nuclei. Proceedings of the National Academy of Sciences of the United States of America. 110: 19802-7. PMID 24248345 DOI: 10.1073/Pnas.1319700110  0.532
2013 Bekinschtein P, Kent BA, Oomen CA, Clemenson GD, Gage FH, Saksida LM, Bussey TJ. BDNF in the dentate gyrus is required for consolidation of "pattern-separated" memories. Cell Reports. 5: 759-68. PMID 24209752 DOI: 10.1016/J.Celrep.2013.09.027  0.693
2013 McConnell MJ, Lindberg MR, Brennand KJ, Piper JC, Voet T, Cowing-Zitron C, Shumilina S, Lasken RS, Vermeesch JR, Hall IM, Gage FH. Mosaic copy number variation in human neurons. Science (New York, N.Y.). 342: 632-7. PMID 24179226 DOI: 10.1126/Science.1243472  0.742
2013 Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, Å estan N, ... Gage FH, et al. Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development (Cambridge, England). 140: 4633-44. PMID 24154525 DOI: 10.1242/Dev.097212  0.673
2013 Marchetto MC, Narvaiza I, Denli AM, Benner C, Lazzarini TA, Nathanson JL, Paquola AC, Desai KN, Herai RH, Weitzman MD, Yeo GW, Muotri AR, Gage FH. Differential L1 regulation in pluripotent stem cells of humans and apes. Nature. 503: 525-9. PMID 24153179 DOI: 10.1038/Nature12686  0.795
2013 Deshmukh VA, Tardif V, Lyssiotis CA, Green CC, Kerman B, Kim HJ, Padmanabhan K, Swoboda JG, Ahmad I, Kondo T, Gage FH, Theofilopoulos AN, Lawson BR, Schultz PG, Lairson LL. A regenerative approach to the treatment of multiple sclerosis. Nature. 502: 327-32. PMID 24107995 DOI: 10.1038/Nature12647  0.788
2013 Tang X, Zhou L, Wagner AM, Marchetto MC, Muotri AR, Gage FH, Chen G. Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells. Stem Cell Research. 11: 743-57. PMID 23759711 DOI: 10.1016/J.Scr.2013.05.002  0.691
2013 Rangel LM, Quinn LK, Chiba AA, Gage FH, Aimone JB. A hypothesis for temporal coding of young and mature granule cells. Frontiers in Neuroscience. 7: 75. PMID 23717259 DOI: 10.3389/Fnins.2013.00075  0.823
2013 Li Y, Stam FJ, Aimone JB, Goulding M, Callaway EM, Gage FH. Molecular layer perforant path-associated cells contribute to feed-forward inhibition in the adult dentate gyrus. Proceedings of the National Academy of Sciences of the United States of America. 110: 9106-11. PMID 23671081 DOI: 10.1073/Pnas.1306912110  0.834
2013 Shimozaki K, Clemenson GD, Gage FH. Paired related homeobox protein 1 is a regulator of stemness in adult neural stem/progenitor cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4066-75. PMID 23447615 DOI: 10.1523/Jneurosci.4586-12.2013  0.774
2013 Kurian L, Sancho-Martinez I, Nivet E, Aguirre A, Moon K, Pendaries C, Volle-Challier C, Bono F, Herbert JM, Pulecio J, Xia Y, Li M, Montserrat N, Ruiz S, Dubova I, ... ... Gage FH, et al. Conversion of human fibroblasts to angioblast-like progenitor cells. Nature Methods. 10: 77-83. PMID 23202434 DOI: 10.1038/Nmeth.2255  0.737
2013 Zhao C, Toni N, Gage FH. Synaptogenesis in the Adult CNS - Hippocampus Cellular Migration and Formation of Neuronal Connections. 723-738. DOI: 10.1016/B978-0-12-397266-8.00111-3  0.695
2013 Brennand K, Gage F. Neural Induction of Embryonic Stem/Induced Pluripotent Stem Cells Patterning and Cell Type Specification in the Developing Cns and Pns. 111-129. DOI: 10.1016/B978-0-12-397265-1.00046-0  0.567
2013 McConnell MJ, Gage FH. Neuronal Genomic and Epigenetic Diversity Epigenetic Regulation in the Nervous System. 281-298. DOI: 10.1016/B978-0-12-391494-1.00011-2  0.551
2012 Winner B, Regensburger M, Schreglmann S, Boyer L, Prots I, Rockenstein E, Mante M, Zhao C, Winkler J, Masliah E, Gage FH. Role of α-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16906-16. PMID 23175842 DOI: 10.1523/Jneurosci.2723-12.2012  0.546
2012 Vivar C, Potter MC, Choi J, Lee JY, Stringer TP, Callaway EM, Gage FH, Suh H, van Praag H. Monosynaptic inputs to new neurons in the dentate gyrus. Nature Communications. 3: 1107. PMID 23033083 DOI: 10.1038/Ncomms2101  0.744
2012 Giorgetti A, Marchetto MC, Li M, Yu D, Fazzina R, Mu Y, Adamo A, Paramonov I, Cardoso JC, Monasterio MB, Bardy C, Cassiani-Ingoni R, Liu GH, Gage FH, Izpisua Belmonte JC. Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc. Proceedings of the National Academy of Sciences of the United States of America. 109: 12556-61. PMID 22814375 DOI: 10.1073/Pnas.1209523109  0.348
2012 Yao J, Mu Y, Gage FH. Neural stem cells: mechanisms and modeling. Protein & Cell. 3: 251-61. PMID 22549585 DOI: 10.1007/S13238-012-2033-6  0.497
2012 Brennand KJ, Simone A, Tran N, Gage FH. Modeling psychiatric disorders at the cellular and network levels. Molecular Psychiatry. 17: 1239-53. PMID 22472874 DOI: 10.1038/Mp.2012.20  0.643
2012 Bracko O, Singer T, Aigner S, Knobloch M, Winner B, Ray J, Clemenson GD, Suh H, Couillard-Despres S, Aigner L, Gage FH, Jessberger S. Gene expression profiling of neural stem cells and their neuronal progeny reveals IGF2 as a regulator of adult hippocampal neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3376-87. PMID 22399759 DOI: 10.1523/Jneurosci.4248-11.2012  0.836
2012 Gage FH, Muotri AR. What makes each brain unique. Scientific American. 306: 26-31. PMID 22375319 DOI: 10.1038/scientificamerican0312-20  0.496
2012 Li Y, Aimone JB, Xu X, Callaway EM, Gage FH. Development of GABAergic inputs controls the contribution of maturing neurons to the adult hippocampal network. Proceedings of the National Academy of Sciences of the United States of America. 109: 4290-5. PMID 22371596 DOI: 10.1073/pnas.1120754109  0.832
2012 Thuret S, Thallmair M, Horky LL, Gage FH. Enhanced functional recovery in MRL/MpJ mice after spinal cord dorsal hemisection. Plos One. 7: e30904. PMID 22348029 DOI: 10.1371/Journal.Pone.0030904  0.781
2012 Han J, Denli AM, Gage FH. The enemy within: intronic miR-26b represses its host gene, ctdsp2, to regulate neurogenesis. Genes & Development. 26: 6-10. PMID 22215805 DOI: 10.1101/Gad.184416.111  0.747
2012 Boyce VS, Park J, Gage FH, Mendell LM. Differential effects of brain-derived neurotrophic factor and neurotrophin-3 on hindlimb function in paraplegic rats. The European Journal of Neuroscience. 35: 221-32. PMID 22211901 DOI: 10.1111/j.1460-9568.2011.07950.x  0.562
2012 Shimozaki K, Zhang CL, Suh H, Denli AM, Evans RM, Gage FH. SRY-box-containing gene 2 regulation of nuclear receptor tailless (Tlx) transcription in adult neural stem cells. The Journal of Biological Chemistry. 287: 5969-78. PMID 22194602 DOI: 10.1074/Jbc.M111.290403  0.8
2012 Lee SW, Clemenson GD, Gage FH. New neurons in an aged brain. Behavioural Brain Research. 227: 497-507. PMID 22024433 DOI: 10.1016/J.Bbr.2011.10.009  0.829
2012 Zhao C, Warner-Schmidt J, Duman RS, Gage FH. Electroconvulsive seizure promotes spine maturation in newborn dentate granule cells in adult rat. Developmental Neurobiology. 72: 937-42. PMID 21976455 DOI: 10.1002/Dneu.20986  0.466
2012 Brennand KJ, Gage FH. Modeling psychiatric disorders through reprogramming. Disease Models & Mechanisms. 5: 26-32. PMID 21954066 DOI: 10.1242/Dmm.008268  0.57
2012 Yao J, Mu Y, Gage FH. Erratum to: Neural stem cells: mechanisms and modeling Protein & Cell. 3: 559-559. DOI: 10.1007/S13238-012-2808-9  0.379
2011 Coufal NG, Garcia-Perez JL, Peng GE, Marchetto MC, Muotri AR, Mu Y, Carson CT, Macia A, Moran JV, Gage FH. Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 20382-7. PMID 22159035 DOI: 10.1073/Pnas.1100273108  0.716
2011 Brennand KJ, Gage FH. Concise review: the promise of human induced pluripotent stem cell-based studies of schizophrenia. Stem Cells (Dayton, Ohio). 29: 1915-22. PMID 22009633 DOI: 10.1002/Stem.762  0.63
2011 Kuwabara T, Kagalwala MN, Onuma Y, Ito Y, Warashina M, Terashima K, Sanosaka T, Nakashima K, Gage FH, Asashima M. Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb. Embo Molecular Medicine. 3: 742-54. PMID 21984534 DOI: 10.1002/Emmm.201100177  0.82
2011 Zhu Q, Pao GM, Huynh AM, Suh H, Tonnu N, Nederlof PM, Gage FH, Verma IM. BRCA1 tumour suppression occurs via heterochromatin-mediated silencing. Nature. 477: 179-84. PMID 21901007 DOI: 10.1038/Nature10371  0.524
2011 Marchetto MC, Brennand KJ, Boyer LF, Gage FH. Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises. Human Molecular Genetics. 20: R109-15. PMID 21828073 DOI: 10.1093/Hmg/Ddr336  0.589
2011 Hester ME, Murtha MJ, Song S, Rao M, Miranda CJ, Meyer K, Tian J, Boulting G, Schaffer DV, Zhu MX, Pfaff SL, Gage FH, Kaspar BK. Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1905-12. PMID 21772256 DOI: 10.1038/Mt.2011.135  0.699
2011 Aimone JB, Deng W, Gage FH. Resolving new memories: a critical look at the dentate gyrus, adult neurogenesis, and pattern separation. Neuron. 70: 589-96. PMID 21609818 DOI: 10.1016/J.Neuron.2011.05.010  0.801
2011 Woods NB, Parker AS, Moraghebi R, Lutz MK, Firth AL, Brennand KJ, Berggren WT, Raya A, Izpisúa Belmonte JC, Gage FH, Verma IM. Brief report: efficient generation of hematopoietic precursors and progenitors from human pluripotent stem cell lines. Stem Cells (Dayton, Ohio). 29: 1158-64. PMID 21544903 DOI: 10.1002/Stem.657  0.563
2011 Brennand KJ, Simone A, Jou J, Gelboin-Burkhart C, Tran N, Sangar S, Li Y, Mu Y, Chen G, Yu D, McCarthy S, Sebat J, Gage FH. Modelling schizophrenia using human induced pluripotent stem cells. Nature. 473: 221-5. PMID 21490598 DOI: 10.1038/Nature09915  0.722
2011 Mu Y, Zhao C, Gage FH. Dopaminergic modulation of cortical inputs during maturation of adult-born dentate granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4113-23. PMID 21411652 DOI: 10.1523/Jneurosci.4913-10.2011  0.535
2011 Aimone JB, Gage FH. Modeling new neuron function: a history of using computational neuroscience to study adult neurogenesis. The European Journal of Neuroscience. 33: 1160-9. PMID 21395860 DOI: 10.1111/j.1460-9568.2011.07615.x  0.808
2011 Winner B, Jappelli R, Maji SK, Desplats PA, Boyer L, Aigner S, Hetzer C, Loher T, Vilar M, Campioni S, Tzitzilonis C, Soragni A, Jessberger S, Mira H, Consiglio A, ... ... Gage FH, et al. In vivo demonstration that alpha-synuclein oligomers are toxic. Proceedings of the National Academy of Sciences of the United States of America. 108: 4194-9. PMID 21325059 DOI: 10.1073/Pnas.1100976108  0.684
2011 Kim JE, O'Sullivan ML, Sanchez CA, Hwang M, Israel MA, Brennand K, Deerinck TJ, Goldstein LS, Gage FH, Ellisman MH, Ghosh A. Investigating synapse formation and function using human pluripotent stem cell-derived neurons. Proceedings of the National Academy of Sciences of the United States of America. 108: 3005-10. PMID 21278334 DOI: 10.1073/Pnas.1007753108  0.64
2011 Winner B, Melrose HL, Zhao C, Hinkle KM, Yue M, Kent C, Braithwaite AT, Ogholikhan S, Aigner R, Winkler J, Farrer MJ, Gage FH. Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice. Neurobiology of Disease. 41: 706-16. PMID 21168496 DOI: 10.1016/J.Nbd.2010.12.008  0.57
2011 Giorgetti A, Laricchia-Robbio L, Fazzina R, Marchetto M, Yu D, Li M, Mu Y, Adamo A, Paramonov I, Castaño-Cardoso J, Barragan M, Gage F, Izpisua JC. Cord Blood-derived neurons by ectopic expression of SOX2 and c-MYC Blood. 118: 2350-2350. DOI: 10.1182/Blood.V118.21.2350.2350  0.495
2011 Shimozaki K, Zhang C, Suh H, Denli A, Evans RM, Gage FH. Functional roles of Sox2 for the molecular regulation of TLX/NR2E1 in adult neural stem/progenitor cells Neuroscience Research. 71: e124. DOI: 10.1016/J.Neures.2011.07.531  0.811
2010 Ruiz S, Brennand K, Panopoulos AD, Herrerías A, Gage FH, Izpisua-Belmonte JC. High-efficient generation of induced pluripotent stem cells from human astrocytes. Plos One. 5: e15526. PMID 21170306 DOI: 10.1371/Journal.Pone.0015526  0.596
2010 Muotri AR, Marchetto MC, Coufal NG, Oefner R, Yeo G, Nakashima K, Gage FH. L1 retrotransposition in neurons is modulated by MeCP2. Nature. 468: 443-6. PMID 21085180 DOI: 10.1038/Nature09544  0.798
2010 Marchetto MC, Carromeu C, Acab A, Yu D, Yeo GW, Mu Y, Chen G, Gage FH, Muotri AR. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell. 143: 527-39. PMID 21074045 DOI: 10.1016/J.Cell.2010.10.016  0.739
2010 Ma DK, Marchetto MC, Guo JU, Ming GL, Gage FH, Song H. Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nature Neuroscience. 13: 1338-44. PMID 20975758 DOI: 10.1038/nn.2672  0.809
2010 Mathews EA, Morgenstern NA, Piatti VC, Zhao C, Jessberger S, Schinder AF, Gage FH. A distinctive layering pattern of mouse dentate granule cells is generated by developmental and adult neurogenesis. The Journal of Comparative Neurology. 518: 4479-90. PMID 20886617 DOI: 10.1002/Cne.22489  0.818
2010 Gage FH. Molecular and cellular mechanisms contributing to the regulation, proliferation and differentiation of neural stem cells in the adult dentate gyrus. The Keio Journal of Medicine. 59: 79-83. PMID 20881448  0.375
2010 Petruska JC, Kitay B, Boyce VS, Kaspar BK, Pearse DD, Gage FH, Mendell LM. Intramuscular AAV delivery of NT-3 alters synaptic transmission to motoneurons in adult rats. The European Journal of Neuroscience. 32: 997-1005. PMID 20849530 DOI: 10.1111/J.1460-9568.2010.07392.X  0.685
2010 Aimone JB, Deng W, Gage FH. Put them out to pasture? What are old granule cells good for, anyway...? Hippocampus. 20: 1124-5. PMID 20848611 DOI: 10.1002/Hipo.20867  0.814
2010 Liu D, Ou L, Clemenson GD, Chao C, Lutske ME, Zambetti GP, Gage FH, Xu Y. Puma is required for p53-induced depletion of adult stem cells. Nature Cell Biology. 12: 993-8. PMID 20818388 DOI: 10.1038/Ncb2100  0.714
2010 Valdez G, Tapia JC, Kang H, Clemenson GD, Gage FH, Lichtman JW, Sanes JR. Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise. Proceedings of the National Academy of Sciences of the United States of America. 107: 14863-8. PMID 20679195 DOI: 10.1073/Pnas.1002220107  0.701
2010 Mira H, Andreu Z, Suh H, Lie DC, Jessberger S, Consiglio A, San Emeterio J, Hortigüela R, Marqués-Torrejón MA, Nakashima K, Colak D, Götz M, Fariñas I, Gage FH. Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus. Cell Stem Cell. 7: 78-89. PMID 20621052 DOI: 10.1016/J.Stem.2010.04.016  0.823
2010 Aimone JB, Deng W, Gage FH. Adult neurogenesis: integrating theories and separating functions. Trends in Cognitive Sciences. 14: 325-37. PMID 20471301 DOI: 10.1016/J.Tics.2010.04.003  0.816
2010 Mu Y, Lee SW, Gage FH. Signaling in adult neurogenesis. Current Opinion in Neurobiology. 20: 416-23. PMID 20471243 DOI: 10.1016/J.Conb.2010.04.010  0.843
2010 Singer T, McConnell MJ, Marchetto MC, Coufal NG, Gage FH. LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes? Trends in Neurosciences. 33: 345-54. PMID 20471112 DOI: 10.1016/J.Tins.2010.04.001  0.733
2010 Deng W, Aimone JB, Gage FH. New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nature Reviews. Neuroscience. 11: 339-50. PMID 20354534 DOI: 10.1038/Nrn2822  0.811
2010 Gage F. The promise and the challenge of modelling human disease in a dish. Embo Molecular Medicine. 2: 77-8. PMID 20166113 DOI: 10.1002/emmm.201000060  0.381
2010 Qu Q, Sun G, Li W, Yang S, Ye P, Zhao C, Yu RT, Gage FH, Evans RM, Shi Y. Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal. Nature Cell Biology. 12: 31-40; sup pp 1-9. PMID 20010817 DOI: 10.1038/ncb2001  0.456
2010 Zhao C, Gage FH. Neural stem cells: Adult neurogenesis Encyclopedia of Neuroscience. 239-245. DOI: 10.1016/B978-008045046-9.01023-8  0.492
2009 Overall RW, Kempermann G, Peirce J, Lu L, Goldowitz D, Gage FH, Goodwin S, Smit AB, Airey DC, Rosen GD, Schalkwyk LC, Sutter TR, Nowakowski RS, Whatley S, Williams RW. Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource. Frontiers in Neuroscience. 3: 55. PMID 20582282 DOI: 10.3389/Neuro.15.003.2009  0.727
2009 Nakashima K, Kohyama J, Namihira M, Gage FH, Okano H, Sawamoto K. [Epigenetic mechanisms regulating neural cell fate determination]. No to Hattatsu. Brain and Development. 41: 411-4. PMID 19928537  0.302
2009 Jessberger S, Gage FH, Eisch AJ, Lagace DC. Making a neuron: Cdk5 in embryonic and adult neurogenesis. Trends in Neurosciences. 32: 575-82. PMID 19782409 DOI: 10.1016/J.Tins.2009.07.002  0.773
2009 Muotri AR, Zhao C, Marchetto MC, Gage FH. Environmental influence on L1 retrotransposons in the adult hippocampus. Hippocampus. 19: 1002-7. PMID 19771587 DOI: 10.1002/Hipo.20564  0.699
2009 Marchetto MC, Yeo GW, Kainohana O, Marsala M, Gage FH, Muotri AR. Transcriptional signature and memory retention of human-induced pluripotent stem cells. Plos One. 4: e7076. PMID 19763270 DOI: 10.1371/Journal.Pone.0007076  0.676
2009 Tamaki SJ, Jacobs Y, Dohse M, Capela A, Cooper JD, Reitsma M, He D, Tushinski R, Belichenko PV, Salehi A, Mobley W, Gage FH, Huhn S, Tsukamoto AS, Weissman IL, et al. Neuroprotection of host cells by human central nervous system stem cells in a mouse model of infantile neuronal ceroid lipofuscinosis. Cell Stem Cell. 5: 310-9. PMID 19733542 DOI: 10.1016/J.Stem.2009.05.022  0.341
2009 Kuwabara T, Hsieh J, Muotri A, Yeo G, Warashina M, Lie DC, Moore L, Nakashima K, Asashima M, Gage FH. Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis. Nature Neuroscience. 12: 1097-105. PMID 19701198 DOI: 10.1038/Nn.2360  0.8
2009 Coufal NG, Garcia-Perez JL, Peng GE, Yeo GW, Mu Y, Lovci MT, Morell M, O'Shea KS, Moran JV, Gage FH. L1 retrotransposition in human neural progenitor cells. Nature. 460: 1127-31. PMID 19657334 DOI: 10.1038/Nature08248  0.721
2009 Suh H, Deng W, Gage FH. Signaling in adult neurogenesis. Annual Review of Cell and Developmental Biology. 25: 253-75. PMID 19575663 DOI: 10.1146/Annurev.Cellbio.042308.113256  0.631
2009 Jagasia R, Steib K, Englberger E, Herold S, Faus-Kessler T, Saxe M, Gage FH, Song H, Lie DC. GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7966-77. PMID 19553437 DOI: 10.1523/JNEUROSCI.1054-09.2009  0.547
2009 Li Y, Mu Y, Gage FH. Development of neural circuits in the adult hippocampus. Current Topics in Developmental Biology. 87: 149-74. PMID 19427519 DOI: 10.1016/S0070-2153(09)01205-8  0.398
2009 Denli AM, Cao X, Gage FH. miR-9 and TLX: chasing tails in neural stem cells. Nature Structural & Molecular Biology. 16: 346-7. PMID 19343066 DOI: 10.1038/Nsmb0409-346  0.73
2009 Zhao C, Suh H, Gage FH. Notch keeps ependymal cells in line. Nature Neuroscience. 12: 243-5. PMID 19238183 DOI: 10.1038/Nn0309-243  0.674
2009 Aimone JB, Wiles J, Gage FH. Computational influence of adult neurogenesis on memory encoding. Neuron. 61: 187-202. PMID 19186162 DOI: 10.1016/J.Neuron.2008.11.026  0.804
2009 Jessberger S, Clark RE, Broadbent NJ, Clemenson GD, Consiglio A, Lie DC, Squire LR, Gage FH. Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats. Learning & Memory (Cold Spring Harbor, N.Y.). 16: 147-54. PMID 19181621 DOI: 10.1101/Lm.1172609  0.829
2009 Thuret S, Toni N, Aigner S, Yeo GW, Gage FH. Hippocampus-dependent learning is associated with adult neurogenesis in MRL/MpJ mice. Hippocampus. 19: 658-69. PMID 19140178 DOI: 10.1002/Hipo.20550  0.701
2009 Yeo GW, Coufal NG, Liang TY, Peng GE, Fu XD, Gage FH. An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. Nature Structural & Molecular Biology. 16: 130-7. PMID 19136955 DOI: 10.1038/Nsmb.1545  0.709
2009 Jessberger S, Gage FH. Fate plasticity of adult hippocampal progenitors: biological relevance and therapeutic use. Trends in Pharmacological Sciences. 30: 61-5. PMID 19135265 DOI: 10.1016/J.Tips.2008.11.003  0.79
2009 Marumoto T, Tashiro A, Friedmann-Morvinski D, Scadeng M, Soda Y, Gage FH, Verma IM. Development of a novel mouse glioma model using lentiviral vectors. Nature Medicine. 15: 110-6. PMID 19122659 DOI: 10.1038/Nm.1863  0.549
2008 Jessberger S, Gage FH. Stem-cell-associated structural and functional plasticity in the aging hippocampus. Psychology and Aging. 23: 684-91. PMID 19140640 DOI: 10.1037/A0014188  0.699
2008 Thompson CL, Pathak SD, Jeromin A, Ng LL, MacPherson CR, Mortrud MT, Cusick A, Riley ZL, Sunkin SM, Bernard A, Puchalski RB, Gage FH, Jones AR, Bajic VB, Hawrylycz MJ, et al. Genomic anatomy of the hippocampus. Neuron. 60: 1010-21. PMID 19109908 DOI: 10.1016/J.Neuron.2008.12.008  0.613
2008 Marchetto MC, Muotri AR, Mu Y, Smith AM, Cezar GG, Gage FH. Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells. Cell Stem Cell. 3: 649-57. PMID 19041781 DOI: 10.1016/J.Stem.2008.10.001  0.582
2008 Kohyama J, Kojima T, Takatsuka E, Yamashita T, Namiki J, Hsieh J, Gage FH, Namihira M, Okano H, Sawamoto K, Nakashima K. Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain. Proceedings of the National Academy of Sciences of the United States of America. 105: 18012-7. PMID 19004774 DOI: 10.1073/Pnas.0808417105  0.672
2008 Jessberger S, Aigner S, Clemenson GD, Toni N, Lie DC, Karalay O, Overall R, Kempermann G, Gage FH. Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus. Plos Biology. 6: e272. PMID 18998770 DOI: 10.1371/Journal.Pbio.0060272  0.83
2008 Li X, Barkho BZ, Luo Y, Smrt RD, Santistevan NJ, Liu C, Kuwabara T, Gage FH, Zhao X. Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells. The Journal of Biological Chemistry. 283: 27644-52. PMID 18689796 DOI: 10.1074/Jbc.M804899200  0.594
2008 Yeo GW, Coufal N, Aigner S, Winner B, Scolnick JA, Marchetto MC, Muotri AR, Carson C, Gage FH. Multiple layers of molecular controls modulate self-renewal and neuronal lineage specification of embryonic stem cells. Human Molecular Genetics. 17: R67-75. PMID 18632700 DOI: 10.1093/Hmg/Ddn065  0.825
2008 Toni N, Laplagne DA, Zhao C, Lombardi G, Ribak CE, Gage FH, Schinder AF. Neurons born in the adult dentate gyrus form functional synapses with target cells. Nature Neuroscience. 11: 901-7. PMID 18622400 DOI: 10.1038/Nn.2156  0.831
2008 Jessberger S, Toni N, Clemenson GD, Ray J, Gage FH. Directed differentiation of hippocampal stem/progenitor cells in the adult brain. Nature Neuroscience. 11: 888-93. PMID 18587391 DOI: 10.1038/Nn.2148  0.839
2008 Zhao C, Deng W, Gage FH. Mechanisms and functional implications of adult neurogenesis. Cell. 132: 645-60. PMID 18295581 DOI: 10.1016/J.Cell.2008.01.033  0.557
2008 Zhang CL, Zou Y, He W, Gage FH, Evans RM. A role for adult TLX-positive neural stem cells in learning and behaviour. Nature. 451: 1004-7. PMID 18235445 DOI: 10.1038/nature06562  0.372
2008 Jessberger S, Aigner S, Aimone JB, Gage FH. Adult neural progenitor cells in CNS function and disease Cns Regeneration. 181-200. DOI: 10.1016/B978-012373994-0.50009-9  0.813
2007 Suh H, Consiglio A, Ray J, Sawai T, D'Amour KA, Gage FH. In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus. Cell Stem Cell. 1: 515-28. PMID 18371391 DOI: 10.1016/J.Stem.2007.09.002  0.844
2007 Parent JM, Jessberger S, Gage FH, Gong C. Is neurogenesis reparative after status epilepticus? Epilepsia. 48: 69-71. PMID 18330005 DOI: 10.1111/J.1528-1167.2007.01355.X  0.675
2007 Cezar GG, Quam JA, Smith AM, Rosa GJ, Piekarczyk MS, Brown JF, Gage FH, Muotri AR. Identification of small molecules from human embryonic stem cells using metabolomics. Stem Cells and Development. 16: 869-82. PMID 18042039 DOI: 10.1089/Scd.2007.0022  0.551
2007 Yeo GW, Xu X, Liang TY, Muotri AR, Carson CT, Coufal NG, Gage FH. Alternative splicing events identified in human embryonic stem cells and neural progenitors. Plos Computational Biology. 3: 1951-67. PMID 17967047 DOI: 10.1371/Journal.Pcbi.0030196  0.791
2007 Muotri AR, Marchetto MC, Coufal NG, Gage FH. The necessary junk: new functions for transposable elements. Human Molecular Genetics. 16: R159-67. PMID 17911158 DOI: 10.1093/Hmg/Ddm196  0.716
2007 Jessberger S, Zhao C, Toni N, Clemenson GD, Li Y, Gage FH. Seizure-associated, aberrant neurogenesis in adult rats characterized with retrovirus-mediated cell labeling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9400-7. PMID 17728453 DOI: 10.1523/Jneurosci.2002-07.2007  0.815
2007 Aigner S, Denli AM, Gage FH. A novel model for an older remodeler: the BAF swap in neurogenesis. Neuron. 55: 171-3. PMID 17640518 DOI: 10.1016/J.Neuron.2007.07.004  0.76
2007 Jessberger S, Nakashima K, Clemenson GD, Mejia E, Mathews E, Ure K, Ogawa S, Sinton CM, Gage FH, Hsieh J. Epigenetic modulation of seizure-induced neurogenesis and cognitive decline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5967-75. PMID 17537967 DOI: 10.1523/Jneurosci.0110-07.2007  0.792
2007 van Praag H, Lucero MJ, Yeo GW, Stecker K, Heivand N, Zhao C, Yip E, Afanador M, Schroeter H, Hammerstone J, Gage FH. Plant-derived flavanol (-)epicatechin enhances angiogenesis and retention of spatial memory in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5869-78. PMID 17537957 DOI: 10.1523/Jneurosci.0914-07.2007  0.595
2007 Smrt RD, Eaves-Egenes J, Barkho BZ, Santistevan NJ, Zhao C, Aimone JB, Gage FH, Zhao X. Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons. Neurobiology of Disease. 27: 77-89. PMID 17532643 DOI: 10.1016/J.Nbd.2007.04.005  0.827
2007 Laplagne DA, Kamienkowski JE, Espósito MS, Piatti VC, Zhao C, Gage FH, Schinder AF. Similar GABAergic inputs in dentate granule cells born during embryonic and adult neurogenesis. The European Journal of Neuroscience. 25: 2973-81. PMID 17509085 DOI: 10.1111/J.1460-9568.2007.05549.X  0.83
2007 Toni N, Teng EM, Bushong EA, Aimone JB, Zhao C, Consiglio A, van Praag H, Martone ME, Ellisman MH, Gage FH. Synapse formation on neurons born in the adult hippocampus. Nature Neuroscience. 10: 727-34. PMID 17486101 DOI: 10.1038/Nn1908  0.827
2007 Garcia-Perez JL, Marchetto MC, Muotri AR, Coufal NG, Gage FH, O'Shea KS, Moran JV. LINE-1 retrotransposition in human embryonic stem cells. Human Molecular Genetics. 16: 1569-77. PMID 17468180 DOI: 10.1093/Hmg/Ddm105  0.715
2007 Tashiro A, Makino H, Gage FH. Experience-specific functional modification of the dentate gyrus through adult neurogenesis: a critical period during an immature stage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3252-9. PMID 17376985 DOI: 10.1523/Jneurosci.4941-06.2007  0.724
2007 Leingärtner A, Thuret S, Kroll TT, Chou SJ, Leasure JL, Gage FH, O'Leary DD. Cortical area size dictates performance at modality-specific behaviors. Proceedings of the National Academy of Sciences of the United States of America. 104: 4153-8. PMID 17360492 DOI: 10.1073/Pnas.0611723104  0.648
2007 Jessberger S, Gage FH. ZOOMING IN: a new high-resolution gene expression atlas of the brain. Molecular Systems Biology. 3: 75. PMID 17262034 DOI: 10.1038/Msb4100122  0.71
2007 Jessberger S, Clemenson GD, Gage FH. Spontaneous fusion and nonclonal growth of adult neural stem cells. Stem Cells (Dayton, Ohio). 25: 871-4. PMID 17185607 DOI: 10.1634/Stemcells.2006-0620  0.816
2007 Suzuki S, Gerhold LM, Böttner M, Rau SW, Dela Cruz C, Yang E, Zhu H, Yu J, Cashion AB, Kindy MS, Merchenthaler I, Gage FH, Wise PM. Estradiol enhances neurogenesis following ischemic stroke through estrogen receptors alpha and beta. The Journal of Comparative Neurology. 500: 1064-75. PMID 17183542 DOI: 10.1002/Cne.21240  0.306
2007 Aimone J, Jessberger S, Gage F. Adult neurogenesis Scholarpedia. 2: 2100. DOI: 10.4249/scholarpedia.2100  0.798
2006 Suhonen J, Ray J, Blömer U, Gage FH, Kaspar B. Ex vivo and in vivo gene delivery to the brain. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 13.3. PMID 18428389 DOI: 10.1002/0471142905.Hg1303S51  0.573
2006 Tashiro A, Zhao C, Gage FH. Retrovirus-mediated single-cell gene knockout technique in adult newborn neurons in vivo. Nature Protocols. 1: 3049-55. PMID 17406567 DOI: 10.1038/Nprot.2006.473  0.685
2006 Miller TM, Kim SH, Yamanaka K, Hester M, Umapathi P, Arnson H, Rizo L, Mendell JR, Gage FH, Cleveland DW, Kaspar BK. Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 19546-51. PMID 17164329 DOI: 10.1073/Pnas.0609411103  0.537
2006 Ramirez-Amaya V, Marrone DF, Gage FH, Worley PF, Barnes CA. Integration of new neurons into functional neural networks. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12237-41. PMID 17122048 DOI: 10.1523/Jneurosci.2195-06.2006  0.375
2006 Laplagne DA, Espósito MS, Piatti VC, Morgenstern NA, Zhao C, van Praag H, Gage FH, Schinder AF. Functional convergence of neurons generated in the developing and adult hippocampus. Plos Biology. 4: e409. PMID 17121455 DOI: 10.1371/Journal.Pbio.0040409  0.834
2006 Tashiro A, Sandler VM, Toni N, Zhao C, Gage FH. NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus. Nature. 442: 929-33. PMID 16906136 DOI: 10.1038/Nature05028  0.785
2006 Bhardwaj RD, Curtis MA, Spalding KL, Buchholz BA, Fink D, Björk-Eriksson T, Nordborg C, Gage FH, Druid H, Eriksson PS, Frisén J. Neocortical neurogenesis in humans is restricted to development. Proceedings of the National Academy of Sciences of the United States of America. 103: 12564-8. PMID 16901981 DOI: 10.1073/Pnas.0605177103  0.355
2006 Jagasia R, Song H, Gage FH, Lie DC. New regulators in adult neurogenesis and their potential role for repair. Trends in Molecular Medicine. 12: 400-5. PMID 16890023 DOI: 10.1016/j.molmed.2006.07.006  0.578
2006 Horky LL, Galimi F, Gage FH, Horner PJ. Fate of endogenous stem/progenitor cells following spinal cord injury. The Journal of Comparative Neurology. 498: 525-38. PMID 16874803 DOI: 10.1002/Cne.21065  0.802
2006 Barkho BZ, Song H, Aimone JB, Smrt RD, Kuwabara T, Nakashima K, Gage FH, Zhao X. Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation. Stem Cells and Development. 15: 407-21. PMID 16846377 DOI: 10.1089/Scd.2006.15.407  0.836
2006 Thallmair M, Ray J, Stallcup WB, Gage FH. Functional and morphological effects of NG2 proteoglycan deletion on hippocampal neurogenesis. Experimental Neurology. 202: 167-78. PMID 16814771 DOI: 10.1016/j.expneurol.2006.05.025  0.339
2006 Muotri AR, Gage FH. Generation of neuronal variability and complexity. Nature. 441: 1087-93. PMID 16810244 DOI: 10.1038/nature04959  0.618
2006 Cao X, Yeo G, Muotri AR, Kuwabara T, Gage FH. Noncoding RNAs in the mammalian central nervous system. Annual Review of Neuroscience. 29: 77-103. PMID 16776580 DOI: 10.1146/Annurev.Neuro.29.051605.112839  0.614
2006 Aimone JB, Wiles J, Gage FH. Potential role for adult neurogenesis in the encoding of time in new memories. Nature Neuroscience. 9: 723-7. PMID 16732202 DOI: 10.1038/Nn1707  0.788
2006 Yang H, Lu P, McKay HM, Bernot T, Keirstead H, Steward O, Gage FH, Edgerton VR, Tuszynski MH. Endogenous neurogenesis replaces oligodendrocytes and astrocytes after primate spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2157-66. PMID 16495442 DOI: 10.1523/Jneurosci.4070-05.2005  0.47
2006 Ray J, Gage FH. Differential properties of adult rat and mouse brain-derived neural stem/progenitor cells. Molecular and Cellular Neurosciences. 31: 560-73. PMID 16426857 DOI: 10.1016/j.mcn.2005.11.010  0.339
2006 Alisch RS, Garcia-Perez JL, Muotri AR, Gage FH, Moran JV. Unconventional translation of mammalian LINE-1 retrotransposons. Genes & Development. 20: 210-24. PMID 16418485 DOI: 10.1101/gad.1380406  0.469
2006 Kempermann G, Chesler EJ, Lu L, Williams RW, Gage FH. Natural variation and genetic covariance in adult hippocampal neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 780-5. PMID 16407118 DOI: 10.1073/Pnas.0510291103  0.562
2006 Zhao C, Teng EM, Summers RG, Ming GL, Gage FH. Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3-11. PMID 16399667 DOI: 10.1523/Jneurosci.3648-05.2006  0.663
2006 Borrell V, Kaspar BK, Gage FH, Callaway EM. In vivo evidence for radial migration of neurons by long-distance somal translocation in the developing ferret visual cortex. Cerebral Cortex (New York, N.Y. : 1991). 16: 1571-83. PMID 16357334 DOI: 10.1093/Cercor/Bhj094  0.724
2006 Warashina M, Min KH, Kuwabara T, Huynh A, Gage FH, Schultz PG, Ding S. A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells. Angewandte Chemie (International Ed. in English). 45: 591-3. PMID 16323231 DOI: 10.1002/Anie.200503089  0.367
2006 Pizzo DP, Coufal NG, Lortie MJ, Gage FH, Thal LJ. Regulatable acetylcholine-producing fibroblasts enhance cognitive performance. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 175-82. PMID 16185935 DOI: 10.1016/J.Ymthe.2005.08.001  0.607
2006 Davis TA, Gage F. Maximal Cord Blood Recovery and CD34+ Progenitor Cell Collection Using Machine Pulsatile Perfusion of Placentas. Blood. 108: 3643-3643. DOI: 10.1182/Blood.V108.11.3643.3643  0.316
2006 Zhao X, Lie DC, Gage FH. Adult-derived stem cells for transplantation in parkinson's Disease Restorative Therapies in Parkinson's Disease. 244-268. DOI: 10.1007/0-387-32823-2_12  0.534
2005 Kuwabara T, Hsieh J, Nakashima K, Warashina M, Taira K, Gage FH. The NRSE smRNA specifies the fate of adult hippocampal neural stem cells. Nucleic Acids Symposium Series (2004). 87-8. PMID 17150646 DOI: 10.1093/nass/49.1.87  0.663
2005 Muotri AR, Nakashima K, Toni N, Sandler VM, Gage FH. Development of functional human embryonic stem cell-derived neurons in mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 102: 18644-8. PMID 16352714 DOI: 10.1073/Pnas.0509315102  0.774
2005 Lie DC, Colamarino SA, Song HJ, Désiré L, Mira H, Consiglio A, Lein ES, Jessberger S, Lansford H, Dearie AR, Gage FH. Wnt signalling regulates adult hippocampal neurogenesis. Nature. 437: 1370-5. PMID 16251967 DOI: 10.1038/Nature04108  0.83
2005 Hsieh J, Gage FH. Chromatin remodeling in neural development and plasticity. Current Opinion in Cell Biology. 17: 664-71. PMID 16226449 DOI: 10.1016/J.Ceb.2005.09.002  0.65
2005 van Praag H, Shubert T, Zhao C, Gage FH. Exercise enhances learning and hippocampal neurogenesis in aged mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8680-5. PMID 16177036 DOI: 10.1523/Jneurosci.1731-05.2005  0.412
2005 Gage FH, McAllister AK. Neuronal and glial cell biology. Current Opinion in Neurobiology. 15: 497-9. PMID 16143511 DOI: 10.1016/j.conb.2005.08.010  0.333
2005 Singer O, Marr RA, Rockenstein E, Crews L, Coufal NG, Gage FH, Verma IM, Masliah E. Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model. Nature Neuroscience. 8: 1343-9. PMID 16136043 DOI: 10.1038/Nn1531  0.58
2005 Muotri AR, Chu VT, Marchetto MC, Deng W, Moran JV, Gage FH. Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition. Nature. 435: 903-10. PMID 15959507 DOI: 10.1038/Nature03663  0.629
2005 Zupanc GK, Hinsch K, Gage FH. Proliferation, migration, neuronal differentiation, and long-term survival of new cells in the adult zebrafish brain. The Journal of Comparative Neurology. 488: 290-319. PMID 15952170 DOI: 10.1002/cne.20571  0.334
2005 Lin W, Dominguez B, Yang J, Aryal P, Brandon EP, Gage FH, Lee KF. Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism. Neuron. 46: 569-79. PMID 15944126 DOI: 10.1016/J.Neuron.2005.04.002  0.662
2005 Kaspar BK, Frost LM, Christian L, Umapathi P, Gage FH. Synergy of insulin-like growth factor-1 and exercise in amyotrophic lateral sclerosis. Annals of Neurology. 57: 649-55. PMID 15852403 DOI: 10.1002/Ana.20451  0.504
2005 Miller TM, Kaspar BK, Kops GJ, Yamanaka K, Christian LJ, Gage FH, Cleveland DW. Virus-delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis. Annals of Neurology. 57: 773-6. PMID 15852369 DOI: 10.1002/Ana.20453  0.542
2005 Lilley CE, Carson CT, Muotri AR, Gage FH, Weitzman MD. DNA repair proteins affect the lifecycle of herpes simplex virus 1. Proceedings of the National Academy of Sciences of the United States of America. 102: 5844-9. PMID 15824307 DOI: 10.1073/pnas.0501916102  0.494
2005 Myers CP, Lewcock JW, Hanson MG, Gosgnach S, Aimone JB, Gage FH, Lee KF, Landmesser LT, Pfaff SL. Cholinergic input is required during embryonic development to mediate proper assembly of spinal locomotor circuits. Neuron. 46: 37-49. PMID 15820692 DOI: 10.1016/J.Neuron.2005.02.022  0.774
2005 Lein ES, Callaway EM, Albright TD, Gage FH. Redefining the boundaries of the hippocampal CA2 subfield in the mouse using gene expression and 3-dimensional reconstruction. The Journal of Comparative Neurology. 485: 1-10. PMID 15776443 DOI: 10.1002/cne.20426  0.694
2005 Martin MJ, Muotri A, Gage F, Varki A. Human embryonic stem cells express an immunogenic nonhuman sialic acid. Nature Medicine. 11: 228-32. PMID 15685172 DOI: 10.1038/Nm1181  0.584
2004 Hsieh J, Nakashima K, Kuwabara T, Mejia E, Gage FH. Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 16659-64. PMID 15537713 DOI: 10.1073/Pnas.0407643101  0.688
2004 Consiglio A, Gritti A, Dolcetta D, Follenzi A, Bordignon C, Gage FH, Vescovi AL, Naldini L. Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors. Proceedings of the National Academy of Sciences of the United States of America. 101: 14835-40. PMID 15466696 DOI: 10.1073/Pnas.0404180101  0.335
2004 Schinder AF, Gage FH. A hypothesis about the role of adult neurogenesis in hippocampal function. Physiology (Bethesda, Md.). 19: 253-61. PMID 15381753 DOI: 10.1152/Physiol.00012.2004  0.701
2004 Hsieh J, Gage FH. Epigenetic control of neural stem cell fate. Current Opinion in Genetics & Development. 14: 461-9. PMID 15380235 DOI: 10.1016/J.Gde.2004.07.006  0.653
2004 Wurmser AE, Nakashima K, Summers RG, Toni N, D'Amour KA, Lie DC, Gage FH. Cell fusion-independent differentiation of neural stem cells to the endothelial lineage. Nature. 430: 350-6. PMID 15254537 DOI: 10.1038/Nature02604  0.817
2004 Pizzo DP, Paban V, Coufal NG, Gage FH, Thal LJ. Long-term production of choline acetyltransferase in the CNS after transplantation of fibroblasts modified with a regulatable vector. Brain Research. Molecular Brain Research. 126: 1-13. PMID 15207910 DOI: 10.1016/J.Molbrainres.2004.03.006  0.627
2004 Brandon EP, Mellott T, Pizzo DP, Coufal N, D'Amour KA, Gobeske K, Lortie M, López-Coviella I, Berse B, Thal LJ, Gage FH, Blusztajn JK. Choline transporter 1 maintains cholinergic function in choline acetyltransferase haploinsufficiency. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5459-66. PMID 15201317 DOI: 10.1523/Jneurosci.1106-04.2004  0.799
2004 Wurmser AE, Palmer TD, Gage FH. Neuroscience. Cellular interactions in the stem cell niche. Science (New York, N.Y.). 304: 1253-5. PMID 15166350 DOI: 10.1126/science.1099344  0.721
2004 Lein ES, Zhao X, Gage FH. Defining a molecular atlas of the hippocampus using DNA microarrays and high-throughput in situ hybridization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3879-89. PMID 15084669 DOI: 10.1523/Jneurosci.4710-03.2004  0.723
2004 Kempermann G, Wiskott L, Gage FH. Functional significance of adult neurogenesis. Current Opinion in Neurobiology. 14: 186-91. PMID 15082323 DOI: 10.1016/j.conb.2004.03.001  0.58
2004 Markakis EA, Palmer TD, Randolph-Moore L, Rakic P, Gage FH. Novel neuronal phenotypes from neural progenitor cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2886-97. PMID 15044527 DOI: 10.1523/JNEUROSCI.4161-03.2004  0.837
2004 Kuwabara T, Hsieh J, Nakashima K, Taira K, Gage FH. A small modulatory dsRNA specifies the fate of adult neural stem cells. Cell. 116: 779-93. PMID 15035981 DOI: 10.1016/S0092-8674(04)00248-X  0.682
2004 Aimone JB, Gage FH. Unbiased characterization of high-density oligonucleotide microarrays using probe-level statistics. Journal of Neuroscience Methods. 135: 27-33. PMID 15020086 DOI: 10.1016/j.jneumeth.2003.11.016  0.769
2004 Schaffer DV, Gage FH. Neurogenesis and neuroadaptation. Neuromolecular Medicine. 5: 1-9. PMID 15001808 DOI: 10.1385/Nmm:5:1:001  0.521
2004 Lie DC, Song H, Colamarino SA, Ming GL, Gage FH. Neurogenesis in the adult brain: new strategies for central nervous system diseases. Annual Review of Pharmacology and Toxicology. 44: 399-421. PMID 14744252 DOI: 10.1146/annurev.pharmtox.44.101802.121631  0.699
2004 Hsieh J, Aimone JB, Kaspar BK, Kuwabara T, Nakashima K, Gage FH. IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes. The Journal of Cell Biology. 164: 111-22. PMID 14709544 DOI: 10.1083/Jcb.200308101  0.822
2004 Shi Y, Chichung Lie D, Taupin P, Nakashima K, Ray J, Yu RT, Gage FH, Evans RM. Expression and function of orphan nuclear receptor TLX in adult neural stem cells. Nature. 427: 78-83. PMID 14702088 DOI: 10.1038/nature02211  0.331
2003 Muotri AR, Gage FH. Vibrating in the background. Nature Genetics. 35: 205-7. PMID 14593403 DOI: 10.1038/ng1103-205  0.43
2003 Aberg MA, Aberg ND, Palmer TD, Alborn AM, Carlsson-Skwirut C, Bang P, Rosengren LE, Olsson T, Gage FH, Eriksson PS. IGF-I has a direct proliferative effect in adult hippocampal progenitor cells. Molecular and Cellular Neurosciences. 24: 23-40. PMID 14550766 DOI: 10.1016/S1044-7431(03)00082-4  0.693
2003 Arvanian VL, Horner PJ, Gage FH, Mendell LM. Chronic neurotrophin-3 strengthens synaptic connections to motoneurons in the neonatal rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8706-12. PMID 14507970 DOI: 10.1523/Jneurosci.23-25-08706.2003  0.725
2003 D'Amour KA, Gage FH. Genetic and functional differences between multipotent neural and pluripotent embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 11866-72. PMID 12923297 DOI: 10.1073/Pnas.1834200100  0.749
2003 Kaspar BK, Lladó J, Sherkat N, Rothstein JD, Gage FH. Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science (New York, N.Y.). 301: 839-42. PMID 12907804 DOI: 10.1126/Science.1086137  0.545
2003 Dickinson-Anson H, Winkler J, Fisher LJ, Song HJ, Poo Mm, Gage FH. Acetylcholine-secreting cells improve age-induced memory deficits. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 51-61. PMID 12842428 DOI: 10.1016/S1525-0016(03)00145-X  0.58
2003 South SM, Kohno T, Kaspar BK, Hegarty D, Vissel B, Drake CT, Ohata M, Jenab S, Sailer AW, Malkmus S, Masuyama T, Horner P, Bogulavsky J, Gage FH, Yaksh TL, et al. A conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5031-40. PMID 12832526 DOI: 10.1523/Jneurosci.23-12-05031.2003  0.729
2003 Brown J, Cooper-Kuhn CM, Kempermann G, Van Praag H, Winkler J, Gage FH, Kuhn HG. Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis. The European Journal of Neuroscience. 17: 2042-6. PMID 12786970 DOI: 10.1046/j.1460-9568.2003.02647.x  0.546
2003 Zhao X, Ueba T, Christie BR, Barkho B, McConnell MJ, Nakashima K, Lein ES, Eadie BD, Willhoite AR, Muotri AR, Summers RG, Chun J, Lee KF, Gage FH. Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proceedings of the National Academy of Sciences of the United States of America. 100: 6777-82. PMID 12748381 DOI: 10.1073/Pnas.1131928100  0.804
2003 Brivanlou AH, Gage FH, Jaenisch R, Jessell T, Melton D, Rossant J. Stem cells. Setting standards for human embryonic stem cells. Science (New York, N.Y.). 300: 913-6. PMID 12738841 DOI: 10.1126/Science.1082940  0.514
2003 Brandon EP, Lin W, D'Amour KA, Pizzo DP, Dominguez B, Sugiura Y, Thode S, Ko CP, Thal LJ, Gage FH, Lee KF. Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 539-49. PMID 12533614 DOI: 10.1523/Jneurosci.23-02-00539.2003  0.776
2003 Lai K, Kaspar BK, Gage FH, Schaffer DV. Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo. Nature Neuroscience. 6: 21-7. PMID 12469128 DOI: 10.1038/Nn983  0.799
2003 Kempermann G, Gast D, Kronenberg G, Yamaguchi M, Gage FH. Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice. Development (Cambridge, England). 130: 391-9. PMID 12466205 DOI: 10.1242/dev.00203  0.615
2002 Horner PJ, Thallmair M, Gage FH. Defining the NG2-expressing cell of the adult CNS. Journal of Neurocytology. 31: 469-80. PMID 14501217 DOI: 10.1023/A:1025739630398  0.711
2002 Zhao X, Gage FH. Expressing the central nervous system. Neurochemical Research. 27: 953-4. PMID 12462397 DOI: 10.1023/A:1020983805928  0.473
2002 Horner PJ, Gage FH. Regeneration in the adult and aging brain. Archives of Neurology. 59: 1717-20. PMID 12433257 DOI: 10.1001/Archneur.59.11.1717  0.67
2002 Kempermann G, Gast D, Gage FH. Neuroplasticity in old age: sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment. Annals of Neurology. 52: 135-43. PMID 12210782 DOI: 10.1002/ana.10262  0.579
2002 Tamaki S, Eckert K, He D, Sutton R, Doshe M, Jain G, Tushinski R, Reitsma M, Harris B, Tsukamoto A, Gage F, Weissman I, Uchida N. Engraftment of sorted/expanded human central nervous system stem cells from fetal brain. Journal of Neuroscience Research. 69: 976-86. PMID 12205691 DOI: 10.1002/Jnr.10412  0.369
2002 Taupin P, Gage FH. Adult neurogenesis and neural stem cells of the central nervous system in mammals Journal of Neuroscience Research. 69: 745-749. PMID 12205667 DOI: 10.1002/jnr.10378  0.307
2002 Kempermann G, Gage FH. Genetic determinants of adult hippocampal neurogenesis correlate with acquisition, but not probe trial performance, in the water maze task. The European Journal of Neuroscience. 16: 129-36. PMID 12153537 DOI: 10.1046/j.1460-9568.2002.02042.x  0.544
2002 Lie DC, Dziewczapolski G, Willhoite AR, Kaspar BK, Shults CW, Gage FH. The adult substantia nigra contains progenitor cells with neurogenic potential. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6639-49. PMID 12151543 DOI: 10.1523/Jneurosci.22-15-06639.2002  0.84
2002 Song H, Stevens CF, Gage FH. Astroglia induce neurogenesis from adult neural stem cells. Nature. 417: 39-44. PMID 11986659 DOI: 10.1038/417039a  0.711
2002 Song HJ, Stevens CF, Gage FH. Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons. Nature Neuroscience. 5: 438-45. PMID 11953752 DOI: 10.1038/nn844  0.721
2002 Kempermann G, Gage FH. Genetic influence on phenotypic differentiation in adult hippocampal neurogenesis. Brain Research. Developmental Brain Research. 134: 1-12. PMID 11947932 DOI: 10.1016/S0165-3806(01)00224-3  0.531
2002 Van Praag H, Gage FH, Lombroso P. Genetics of Childhood Disorders: XXXVI. Stem Cell Research, Part 1: New Neurons in the Adult Brain Journal of the American Academy of Child and Adolescent Psychiatry. 41: 354-356. PMID 11886031 DOI: 10.1097/00004583-200203000-00016  0.337
2002 van Praag H, Schinder AF, Christie BR, Toni N, Palmer TD, Gage FH. Functional neurogenesis in the adult hippocampus. Nature. 415: 1030-4. PMID 11875571 DOI: 10.1038/4151030A  0.844
2002 D'Amour KA, Gage FH. Are somatic stem cells pluripotent or lineage-restricted? Nature Medicine. 8: 213-4. PMID 11875484 DOI: 10.1038/Nm0302-213  0.75
2002 Kaspar BK, Vissel B, Bengoechea T, Crone S, Randolph-Moore L, Muller R, Brandon EP, Schaffer D, Verma IM, Lee KF, Heinemann SF, Gage FH. Adeno-associated virus effectively mediates conditional gene modification in the brain. Proceedings of the National Academy of Sciences of the United States of America. 99: 2320-5. PMID 11842206 DOI: 10.1073/Pnas.042678699  0.815
2002 Kaspar BK, Erickson D, Schaffer D, Hinh L, Gage FH, Peterson DA. Targeted retrograde gene delivery for neuronal protection. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 50-6. PMID 11786045 DOI: 10.1006/mthe.2001.0520  0.74
2001 Zhao X, Lein ES, He A, Smith SC, Aston C, Gage FH. Transcriptional profiling reveals strict boundaries between hippocampal subregions. The Journal of Comparative Neurology. 441: 187-96. PMID 11745644 DOI: 10.1002/Cne.1406  0.697
2001 Weissman IL, Anderson DJ, Gage F. Stem and progenitor cells: Origins, phenotypes, lineage commitments, and transdifferentiations Annual Review of Cell and Developmental Biology. 17: 387-403. PMID 11687494 DOI: 10.1146/annurev.cellbio.17.1.387  0.364
2001 Pfeifer A, Brandon EP, Kootstra N, Gage FH, Verma IM. Delivery of the Cre recombinase by a self-deleting lentiviral vector: Efficient gene targeting in vivo Proceedings of the National Academy of Sciences of the United States of America. 98: 11450-11455. PMID 11553794 DOI: 10.1073/Pnas.201415498  0.684
2001 Palmer TD, Schwartz PH, Taupin P, Kaspar B, Stein SA, Gage FH. Cell culture. Progenitor cells from human brain after death. Nature. 411: 42-3. PMID 11333968 DOI: 10.1038/35075141  0.801
2001 Allen DM, van Praag H, Ray J, Weaver Z, Winrow CJ, Carter TA, Braquet R, Harrington E, Ried T, Brown KD, Gage FH, Barlow C. Ataxia telangiectasia mutated is essential during adult neurogenesis. Genes & Development. 15: 554-66. PMID 11238376 DOI: 10.1101/Gad.869001  0.376
2000 van Praag H, Kempermann G, Gage FH. Neural consequences of environmental enrichment. Nature Reviews. Neuroscience. 1: 191-8. PMID 11257907 DOI: 10.1038/35044558  0.529
2000 Kempermann G, van Praag H, Gage FH. Activity-dependent regulation of neuronal plasticity and self repair. Progress in Brain Research. 127: 35-48. PMID 11142036 DOI: 10.1016/S0079-6123(00)27004-0  0.609
2000 Shihabuddin LS, Horner PJ, Ray J, Gage FH. Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8727-35. PMID 11102479 DOI: 10.1523/Jneurosci.20-23-08727.2000  0.72
2000 Horner PJ, Gage FH. Regenerating the damaged central nervous system. Nature. 407: 963-70. PMID 11069169 DOI: 10.1038/35039559  0.675
2000 Young MJ, Ray J, Whiteley SJ, Klassen H, Gage FH. Neuronal differentiation and morphological integration of hippocampal progenitor cells transplanted to the retina of immature and mature dystrophic rats. Molecular and Cellular Neurosciences. 16: 197-205. PMID 10995547 DOI: 10.1006/Mcne.2000.0869  0.32
2000 Palmer TD, Willhoite AR, Gage FH. Vascular niche for adult hippocampal neurogenesis. The Journal of Comparative Neurology. 425: 479-94. PMID 10975875 DOI: 10.1002/1096-9861(20001002)425:4<479::Aid-Cne2>3.0.Co;2-3  0.83
2000 D'Amour K, Gage FH. New tools for human developmental biology Nature Biotechnology. 18: 381-382. PMID 10748514 DOI: 10.1038/74429  0.712
2000 Horner PJ, Power AE, Kempermann G, Kuhn HG, Palmer TD, Winkler J, Thal LJ, Gage FH. Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 2218-28. PMID 10704497 DOI: 10.1523/Jneurosci.20-06-02218.2000  0.8
2000 Smith D, Roberts J, Gage F, Tuszynski M. 27. Reversal of spontaneous atrophy of cholinergic basal forebrain neurons in the aged primate by ex vivo gene therapy Biological Psychiatry. 47: S7-S8. DOI: 10.1016/S0006-3223(00)00293-6  0.575
1999 van Praag H, Christie BR, Sejnowski TJ, Gage FH. Running enhances neurogenesis, learning, and long-term potentiation in mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 13427-31. PMID 10557337 DOI: 10.1073/pnas.96.23.13427  0.406
1999 Shihabuddin LS, Palmer TD, Gage FH. The search for neural progenitor cells: prospects for the therapy of neurodegenerative disease. Molecular Medicine Today. 5: 474-80. PMID 10529788 DOI: 10.1016/S1357-4310(99)01596-8  0.73
1999 Palmer TD, Markakis EA, Willhoite AR, Safar F, Gage FH. Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8487-97. PMID 10493749 DOI: 10.1523/Jneurosci.19-19-08487.1999  0.843
1999 Smith DE, Roberts J, Gage FH, Tuszynski MH. Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy. Proceedings of the National Academy of Sciences of the United States of America. 96: 10893-8. PMID 10485922 DOI: 10.1073/pnas.96.19.10893  0.546
1999 Kempermann G, Gage FH. Experience-dependent regulation of adult hippocampal neurogenesis: effects of long-term stimulation and stimulus withdrawal. Hippocampus. 9: 321-32. PMID 10401646 DOI: 10.1002/(SICI)1098-1063(1999)9:3<321::AID-HIPO11>3.0.CO;2-C  0.534
1999 Kempermann G, Gage FH. New nerve cells for the adult brain. Scientific American. 280: 48-53. PMID 10231988 DOI: 10.1038/SCIENTIFICAMERICAN0599-48  0.513
1999 Markakis EA, Gage FH. Adult-generated neurons in the dentate gyrus send axonal projections to field CA3 and are surrounded by synaptic vesicles. The Journal of Comparative Neurology. 406: 449-60. PMID 10205022 DOI: 10.1002/(Sici)1096-9861(19990419)406:4<449::Aid-Cne3>3.0.Co;2-I  0.79
1999 van Praag H, Kempermann G, Gage FH. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nature Neuroscience. 2: 266-70. PMID 10195220 DOI: 10.1038/6368  0.531
1999 Ueba T, Kaspar B, Zhao X, Gage FH. Repression of human fibroblast growth factor 2 by a novel transcription factor. The Journal of Biological Chemistry. 274: 10382-7. PMID 10187827 DOI: 10.1074/Jbc.274.15.10382  0.669
1999 Takahashi J, Palmer TD, Gage FH. Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult-derived neural stem cell cultures. Journal of Neurobiology. 38: 65-81. PMID 10027563 DOI: 10.1002/(Sici)1097-4695(199901)38:1<65::Aid-Neu5>3.0.Co;2-Q  0.754
1999 Shihabuddin LS, Ray J, Gage FH. Stem cell technology for basic science and clinical applications Archives of Neurology. 56: 29-32. PMID 9923758 DOI: 10.1001/archneur.56.1.29  0.346
1999 Peterson DA, Dickinson-Anson HA, Leppert JT, Lee KF, Gage FH. Central neuronal loss and behavioral impairment in mice lacking neurotrophin receptor p75. The Journal of Comparative Neurology. 404: 1-20. PMID 9886021 DOI: 10.1002/(Sici)1096-9861(19990201)404:1<1::Aid-Cne1>3.0.Co;2-#  0.494
1998 Takahashi M, Palmer TD, Takahashi J, Gage FH. Widespread integration and survival of adult-derived neural progenitor cells in the developing optic retina. Molecular and Cellular Neurosciences. 12: 340-8. PMID 9888988 DOI: 10.1006/Mcne.1998.0721  0.79
1998 Chiang MY, Misner D, Kempermann G, Schikorski T, Giguère V, Sucov HM, Gage FH, Stevens CF, Evans RM. An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression. Neuron. 21: 1353-61. PMID 9883728 DOI: 10.1016/S0896-6273(00)80654-6  0.602
1998 Eriksson PS, Perfilieva E, Björk-Eriksson T, Alborn AM, Nordborg C, Peterson DA, Gage FH. Neurogenesis in the adult human hippocampus. Nature Medicine. 4: 1313-7. PMID 9809557 DOI: 10.1038/3305  0.564
1998 Aubert I, Ridet JL, Schachner M, Rougon G, Gage FH. Expression of L1 and PSA during sprouting and regeneration in the adult hippocampal formation. The Journal of Comparative Neurology. 399: 1-19. PMID 9725697 DOI: 10.1002/(SICI)1096-9861(19980914)399:1<1::AID-CNE1>3.0.CO;2-5  0.517
1998 Gage FH, Kempermann G, Palmer TD, Peterson DA, Ray J. Multipotent progenitor cells in the adult dentate gyrus. Journal of Neurobiology. 36: 249-66. PMID 9712308 DOI: 10.1002/(SICI)1097-4695(199808)36:2<249::AID-NEU11>3.0.CO;2-9  0.838
1998 Kempermann G, Brandon EP, Gage FH. Environmental stimulation of 129/SvJ mice causes increased cell proliferation and neurogenesis in the adult dentate gyrus. Current Biology : Cb. 8: 939-42. PMID 9707406 DOI: 10.1016/S0960-9822(07)00377-6  0.767
1998 McTigue DM, Horner PJ, Stokes BT, Gage FH. Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5354-65. PMID 9651218 DOI: 10.1523/Jneurosci.18-14-05354.1998  0.744
1998 Kempermann G, Gage FH. Closer to neurogenesis in adult humans. Nature Medicine. 4: 555-7. PMID 9585224 DOI: 10.1038/nm0598-555  0.543
1998 Dickinson-Anson H, Aubert I, Gage FH, Fisher LJ. Hippocampal grafts of acetylcholine-producing cells are sufficient to improve behavioural performance following a unilateral fimbria-fornix lesion. Neuroscience. 84: 771-81. PMID 9579782 DOI: 10.1016/S0306-4522(97)00543-5  0.511
1998 Kempermann G, Kuhn HG, Gage FH. Experience-Induced Neurogenesis in the Senescent Dentate Gyrus The Journal of Neuroscience. 18: 3206-3212. DOI: 10.1523/JNEUROSCI.18-09-03206.1998  0.48
1998 Miyoshi H, Blömer U, Takahashi M, Gage FH, Verma IM. Development of a Self-Inactivating Lentivirus Vector Journal of Virology. 72: 8150-8157. DOI: 10.1128/Jvi.72.10.8150-8157.1998  0.536
1998 Kempermann G, Kuhn HG, Winkler J, Gage FH. New nerve cells for the adult brain. Adult neurogenesis and stem cell concept in neurological research | Neue nervenzellen fur das erwachsene gehirn. Adulte neurogenese und stammzellkonzepte in der neurologischen forschung Nervenarzt. 69: 851-857. DOI: 10.1007/s001150050353  0.552
1997 Kempermann G, Kuhn HG, Gage FH. Genetic influence on neurogenesis in the dentate gyrus of adult mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 10409-14. PMID 9294224 DOI: 10.1073/pnas.94.19.10409  0.557
1997 Miyoshi H, Takahashi M, Gage FH, Verma IM. Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector. Proceedings of the National Academy of Sciences of the United States of America. 94: 10319-23. PMID 9294208 DOI: 10.1073/Pnas.94.19.10319  0.493
1997 Peterson DA, Leppert JT, Lee KF, Gage FH. Basal forebrain neuronal loss in mice lacking neurotrophin receptor p75. Science (New York, N.Y.). 277: 837-9. PMID 9273702 DOI: 10.1126/Science.277.5327.837  0.436
1997 Sah DW, Ray J, Gage FH. Bipotent progenitor cell lines from the human CNS. Nature Biotechnology. 15: 574-80. PMID 9181582 DOI: 10.1038/NBT0697-574  0.334
1997 Palmer TD, Takahashi J, Gage FH. The adult rat hippocampus contains primordial neural stem cells. Molecular and Cellular Neurosciences. 8: 389-404. PMID 9143557 DOI: 10.1006/Mcne.1996.0595  0.764
1997 Kempermann G, Kuhn HG, Gage FH. More hippocampal neurons in adult mice living in an enriched environment. Nature. 386: 493-5. PMID 9087407 DOI: 10.1038/386493a0  0.594
1997 Fagan AM, Suhr ST, Lucidi-Phillipi CA, Peterson DA, Holtzman DM, Gage FH. Endogenous FGF-2 is important for cholinergic sprouting in the denervated hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2499-511. PMID 9065510 DOI: 10.1523/Jneurosci.17-07-02499.1997  0.462
1997 Winkler J, Ramirez GA, Kuhn HG, Peterson DA, Day-Lollini PA, Stewart GR, Tuszynski MH, Gage FH, Thal LJ. Reversible Schwann cell hyperplasia and sprouting of sensory and sympathetic neurites after intraventricular administration of nerve growth factor. Annals of Neurology. 41: 82-93. PMID 9005869 DOI: 10.1002/ana.410410114  0.626
1997 Kuhn HG, Winkler J, Kempermann G, Thal LJ, Gage FH. Epidermal Growth Factor and Fibroblast Growth Factor-2 Have Different Effects on Neural Progenitors in the Adult Rat Brain The Journal of Neuroscience. 17: 5820-5829. DOI: 10.1523/JNEUROSCI.17-15-05820.1997  0.496
1997 Grill R, Murai K, Blesch A, Gage FH, Tuszynski MH. Cellular Delivery of Neurotrophin-3 Promotes Corticospinal Axonal Growth and Partial Functional Recovery after Spinal Cord Injury The Journal of Neuroscience. 17: 5560-5572. DOI: 10.1523/Jneurosci.17-14-05560.1997  0.641
1996 Tuszynski MH, Gage FH. Somatic gene therapy for nervous system disease. Ciba Foundation Symposium. 196: 85-94; discussion 94. PMID 8866129 DOI: 10.1002/9780470514863.CH7  0.539
1996 Suhonen JO, Peterson DA, Ray J, Gage FH. Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo. Nature. 383: 624-7. PMID 8857538 DOI: 10.1038/383624a0  0.553
1996 Chalmers GR, Peterson DA, Gage FH. Sprouting adult CNS cholinergic axons express NILE and associate with astrocytic surfaces expressing neural cell adhesion molecule. The Journal of Comparative Neurology. 371: 287-99. PMID 8835733 DOI: 10.1002/(SICI)1096-9861(19960722)371:2<287::AID-CNE8>3.0.CO;2-Z  0.421
1996 Nakahara Y, Gage FH, Tuszynski MH. Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord. Cell Transplantation. 5: 191-204. PMID 8689031 DOI: 10.1016/0963-6897(95)02028-4  0.492
1996 Hoshimaru M, Ray J, Sah DW, Gage FH. Differentiation of the immortalized adult neuronal progenitor cell line HC2S2 into neurons by regulatable suppression of the v-myc oncogene. Proceedings of the National Academy of Sciences of the United States of America. 93: 1518-23. PMID 8643664 DOI: 10.1073/PNAS.93.4.1518  0.37
1996 Tuszynski MH, Gabriel K, Gage FH, Suhr S, Meyer S, Rosetti A. Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury. Experimental Neurology. 137: 157-73. PMID 8566208 DOI: 10.1006/exnr.1996.0016  0.474
1996 Peterson DA, Lucidi-Phillipi CA, Murphy DP, Ray J, Gage FH. Fibroblast growth factor-2 protects entorhinal layer II glutamatergic neurons from axotomy-induced death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 886-98. PMID 8558257  0.508
1996 Kuhn H, Dickinson-Anson H, Gage F. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation The Journal of Neuroscience. 16: 2027-2033. DOI: 10.1523/JNEUROSCI.16-06-02027.1996  0.445
1996 Nakahara Y, Gage FH, Tuszynski MH. Grafts of Fibroblasts Genetically Modified to Secrete Ngf, Bdnf, Nt-3, or Basic Fgf Elicit Differential Responses in the Adult Spinal Cord Cell Transplantation. 5: 191-204. DOI: 10.1177/096368979600500209  0.476
1996 Suhonen J, Takahashi J, Takahashi M, Palmer T, Ray J, Gage F. 134 Clonal progenitors generated from adult rat hippocampus migrate and differentiate after grafting into embryonic brain International Journal of Developmental Neuroscience. 14: 83-83. DOI: 10.1016/0736-5748(96)80324-8  0.724
1995 Palmer TD, Ray J, Gage FH. FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain. Molecular and Cellular Neurosciences. 6: 474-86. PMID 8581317 DOI: 10.1006/mcne.1995.1035  0.775
1995 Aubert I, Ridet JL, Gage FH. Regeneration in the adult mammalian CNS: guided by development. Current Opinion in Neurobiology. 5: 625-35. PMID 8580714 DOI: 10.1016/0959-4388(95)80068-9  0.585
1995 Gage FH, Coates PW, Palmer TD, Kuhn HG, Fisher LJ, Suhonen JO, Peterson DA, Suhr ST, Ray J. Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proceedings of the National Academy of Sciences of the United States of America. 92: 11879-83. PMID 8524867 DOI: 10.1073/pnas.92.25.11879  0.8
1995 Niijima K, Chalmers GR, Peterson DA, Fisher LJ, Patterson PH, Gage FH. Enhanced survival and neuronal differentiation of adrenal chromaffin cells cografted into the striatum with NGF-producing fibroblasts. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 1180-94. PMID 7869093 DOI: 10.1523/Jneurosci.15-02-01180.1995  0.531
1995 Tuszynski MH, Gage FH. Bridging grafts and transient nerve growth factor infusions promote long-term central nervous system neuronal rescue and partial functional recovery. Proceedings of the National Academy of Sciences of the United States of America. 92: 4621-5. PMID 7753852 DOI: 10.1073/PNAS.92.10.4621  0.53
1995 Gage FH, Ray J, Fisher LJ. Isolation, characterization, and use of stem cells from the CNS Annual Review of Neuroscience. 18: 159-192. PMID 7605059 DOI: 10.1146/ANNUREV.NE.18.030195.001111  0.369
1995 Tuszynski MH, Gage FH. Maintaining the neuronal phenotype after injury in the adult CNS. Neurotrophic factors, axonal growth substrates, and gene therapy. Molecular Neurobiology. 10: 151-67. PMID 7576305 DOI: 10.1007/BF02740673  0.574
1995 Senut MC, Tuszynski MH, Raymon HK, Suhr ST, Liou NH, Jones KR, Reichardt LF, Gage FH. Regional differences in responsiveness of adult CNS axons to grafts of cells expressing human neurotrophin 3. Experimental Neurology. 135: 36-55. PMID 7556552 DOI: 10.1006/exnr.1995.1064  0.555
1995 Chen K, Gage F. Somatic gene transfer of NGF to the aged brain: behavioral and morphological amelioration The Journal of Neuroscience. 15: 2819-2825. DOI: 10.1523/JNEUROSCI.15-04-02819.1995  0.338
1994 Fagan AM, Gage FH. Mechanisms of sprouting in the adult central nervous system: Cellular responses in areas of terminal degeneration and reinnervation in the rat hippocampus Neuroscience. 58: 705-725. PMID 8190252 DOI: 10.1016/0306-4522(94)90449-9  0.341
1994 Tuszynski MH, Gage FH. Neurotrophic factors and diseases of the nervous system. Annals of Neurology. 35: S9-12. PMID 8185304 DOI: 10.1002/ana.410350705  0.55
1994 Peterson DA, Lucidi-Phillipi CA, Eagle KL, Gage FH. Perforant path damage results in progressive neuronal death and somal atrophy in layer II of entorhinal cortex and functional impairment with increasing postdamage age. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 6872-85. PMID 7965084  0.493
1994 Gage FH. Neuronal stem cells: Their characterization and utilization Neurobiology of Aging. 15: 191. PMID 7700451 DOI: 10.1016/0197-4580(94)90203-8  0.334
1993 Ray J, Peterson DA, Schinstine M, Gage FH. Proliferation, differentiation, and long-term culture of primary hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 90: 3602-6. PMID 8475109  0.524
1993 Nilsson OG, Gage FH. Anticholinergic sensitivity in the aging rat septohippocampal system as assessed in a spatial memory task Neurobiology of Aging. 14: 487-497. PMID 8247231 DOI: 10.1016/0197-4580(93)90107-M  0.451
1992 Holtzman DM, Li YW, DeArmond SJ, McKinley MP, Gage FH, Epstein CJ, Mobley WC. Mouse model of neurodegeneration: atrophy of basal forebrain cholinergic neurons in trisomy 16 transplants. Proceedings of the National Academy of Sciences of the United States of America. 89: 1383-7. PMID 1741393 DOI: 10.1073/Pnas.89.4.1383  0.315
1992 Kawaja MD, Gage FH. Morphological and neurochemical features of cultured primary skin fibroblasts of Fischer 344 rats following striatal implantation. The Journal of Comparative Neurology. 317: 102-16. PMID 1573056 DOI: 10.1002/cne.903170108  0.59
1992 Fischer W, Chen KS, Gage FH, Björklund A. Progressive decline in spatial learning and integrity of forebrain cholinergic neurons in rats during aging. Neurobiology of Aging. 13: 9-23. PMID 1311806 DOI: 10.1016/0197-4580(92)90003-G  0.541
1992 Kawaja M, Rosenberg M, Yoshida K, Gage F. Somatic gene transfer of nerve growth factor promotes the survival of axotomized septal neurons and the regeneration of their axons in adult rats The Journal of Neuroscience. 12: 2849-2864. DOI: 10.1523/JNEUROSCI.12-07-02849.1992  0.667
1992 Patterson PH, Niijima K, Chalmers GR, Peterson DA, Fisher LJ, Gage FH. Adrenal chromaffin cell co-grafts with NGF-secreting fibroblasts Journal of Neural Transplantation and Plasticity. 3: 271. DOI: 10.1155/NP.1992.271  0.389
1991 Chen LS, Ray J, Fisher LJ, Kawaja MD, Schinstine M, Kang UJ, Gage FH. Cellular replacement therapy for neurologic disorders: potential of genetically engineered cells. Journal of Cellular Biochemistry. 45: 252-7. PMID 2066374 DOI: 10.1002/Jcb.240450305  0.635
1991 Gage FH, Tuszynski MH, Chen KS, Fagan AM, Higgins GA. Nerve growth factor function in the central nervous system. Current Topics in Microbiology and Immunology. 165: 71-93. PMID 2032465 DOI: 10.1007/978-3-642-75747-1_5  0.418
1991 Kawaja MD, Fagan AM, Firestein BL, Gage FH. Intracerebral grafting of cultured autologous skin fibroblasts into the rat striatum: an assessment of graft size and ultrastructure. The Journal of Comparative Neurology. 307: 695-706. PMID 1869637 DOI: 10.1002/cne.903070414  0.598
1991 Tuszynski MH, Gage FH. In vivo assay of neuron-specific effects of nerve growth factor. Methods in Enzymology. 198: 35-48. PMID 1857228 DOI: 10.1016/0076-6879(91)98006-R  0.5
1991 Schinstine M, Kawaja MD, Gage FH. Intracerebral delivery of growth factors: potential application of genetically modified fibroblasts. Progress in Growth Factor Research. 3: 57-66. PMID 1777600 DOI: 10.1016/0955-2235(91)90013-T  0.618
1991 Gage FH, Kawaja MD, Fisher LJ. Genetically modified cells: applications for intracerebral grafting. Trends in Neurosciences. 14: 328-33. PMID 1721735 DOI: 10.1016/0166-2236(91)90156-O  0.594
1991 Kawaja MD, Gage FH. Reactive astrocytes are substrates for the growth of adult CNS axons in the presence of elevated levels of nerve growth factor. Neuron. 7: 1019-30. PMID 1684900 DOI: 10.1016/0896-6273(91)90346-2  0.6
1991 Kawaja MD, Gage FH. Nerve growth factor receptor immunoreactivity in the rat septohippocampal pathway: a light and electron microscope investigation. The Journal of Comparative Neurology. 307: 517-29. PMID 1649845 DOI: 10.1002/cne.903070313  0.608
1991 Kawaja MD, Ray J, Gage FH. Employment of fibroblasts for gene transfer: applications for grafting into the central nervous system. Genetic Engineering. 13: 205-20. PMID 1367415 DOI: 10.1007/978-1-4615-3760-1_9  0.611
1991 Fischer W, Bjorklund A, Chen K, Gage F. NGF improves spatial memory in aged rodents as a function of age The Journal of Neuroscience. 11: 1889-1906. DOI: 10.1523/Jneurosci.11-07-01889.1991  0.555
1990 Tuszynski MH, Armstrong DM, Gage FH. Basal forebrain cell loss following fimbria/fornix transection. Brain Research. 508: 241-8. PMID 2306615 DOI: 10.1016/0006-8993(90)90402-W  0.509
1990 Mahanthappa NK, Gage FH, Patterson PH. Adrenal chromaffin cells as multipotential neurons for autografts. Progress in Brain Research. 82: 33-9. PMID 2290947 DOI: 10.1016/S0079-6123(08)62587-X  0.331
1990 Tuszynski MH, U HS, Amaral DG, Gage FH. Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 3604-14. PMID 2230949 DOI: 10.1523/Jneurosci.10-11-03604.1990  0.557
1990 Buzsáki G, Chen LS, Gage FH. Spatial organization of physiological activity in the hippocampal region: relevance to memory formation. Progress in Brain Research. 83: 257-68. PMID 2203100 DOI: 10.1016/S0079-6123(08)61255-8  0.302
1990 Gage FH, Rosenberg MB, Tuszynski MH, Yoshida K, Armstrong DM, Hayes RC, Friedmann T. Gene therapy in the CNS: intracerebral grafting of genetically modified cells. Progress in Brain Research. 86: 205-17. PMID 2087558 DOI: 10.1016/S0079-6123(08)63178-7  0.513
1990 Hellweg R, Fischer W, Hock C, Gage FH, Björklund A, Thoenen H. Nerve growth factor levels and choline acetyltransferase activity in the brain of aged rats with spatial memory impairments. Brain Research. 537: 123-30. PMID 2085767 DOI: 10.1016/0006-8993(90)90348-F  0.536
1990 Gage FH, Fisher LJ, Jinnah HA, Rosenberg MB, Tuszynski MH, Friedmann T. Grafting genetically modified cells to the brain: conceptual and technical issues. Progress in Brain Research. 82: 1-10. PMID 1981271 DOI: 10.1016/S0079-6123(08)62584-4  0.52
1990 Tuszynski MH, Buzsaki G, Gage FH. Nerve growth factor infusions combined with fetal hippocampal grafts enhance reconstruction of the lesioned septohippocampal projection. Neuroscience. 36: 33-44. PMID 1699159 DOI: 10.1016/0306-4522(90)90349-9  0.431
1989 Fischer W, Gage FH, Björklund A. Degenerative Changes in Forebrain Cholinergic Nuclei Correlate with Cognitive Impairments in Aged Rats. The European Journal of Neuroscience. 1: 34-45. PMID 12106172 DOI: 10.1111/J.1460-9568.1989.Tb00772.X  0.545
1989 Tuszynski MH, Jinnah HA, Gage FH. Delivery of neuroactive compounds to the brain: potential utility of genetically modified cells. Neurobiology of Aging. 10: 644-5; discussion 64. PMID 2812247 DOI: 10.1016/0197-4580(89)90165-6  0.482
1989 Chen KS, Tuszynski MH, Gage FH. Role of neurotrophic factors in Alzheimer's disease. Neurobiology of Aging. 10: 545-6; discussion 55. PMID 2812224 DOI: 10.1016/0197-4580(89)90124-3  0.524
1989 Gage FH, Dunnett SB, Bjorklund A. Age-related impairments in spatial memory are independent of those in sensorimotor skills. Neurobiology of Aging. 10: 347-52. PMID 2682316 DOI: 10.1016/0197-4580(89)90047-X  0.495
1989 Shapiro ML, Simon DK, Olton DS, Gage FH, Nilsson O, Björklund A. Intrahippocampal grafts of fetal basal forebrain tissue alter place fields in the hippocampus of rats with fimbria-fornix lesions. Neuroscience. 32: 1-18. PMID 2586743 DOI: 10.1016/0306-4522(89)90103-6  0.693
1989 Gage FH, Batchelor P, Chen KS, Chin D, Higgins GA, Koh S, Deputy S, Rosenberg MB, Fischer W, Bjorklund A. NGF receptor reexpression and NGF-mediated cholinergic neuronal hypertrophy in the damaged adult neostriatum. Neuron. 2: 1177-84. PMID 2576209 DOI: 10.1016/0896-6273(89)90184-0  0.563
1989 Batchelor PE, Armstrong DM, Blaker SN, Gage FH. Nerve growth factor receptor and choline acetyltransferase colocalization in neurons within the rat forebrain: response to fimbria-fornix transection. The Journal of Comparative Neurology. 284: 187-204. PMID 2546981 DOI: 10.1002/cne.902840204  0.301
1989 Gage FH, Tuszynski MH, Chen KS, Armstrong D, Buzsáki G. Survival, growth and function of damaged cholinergic neurons. Exs. 57: 259-74. PMID 2533097 DOI: 10.1007/978-3-0348-9138-7_26  0.548
1988 Blaker SN, Armstrong DM, Gage FH. Cholinergic neurons within the rat hippocampus: response to fimbria-fornix transection. The Journal of Comparative Neurology. 272: 127-38. PMID 3385020 DOI: 10.1002/cne.902720109  0.301
1988 Gage FH, Brundin P, Strecker R, Dunnett SB, Isacson O, Bjorklund A. Intracerebral neuronal grafting in experimental animal models of age-related motor dysfunction. Annals of the New York Academy of Sciences. 515: 383-94. PMID 3284426 DOI: 10.1111/J.1749-6632.1988.Tb33014.X  0.722
1988 Rosenberg MB, Friedmann T, Robertson RC, Tuszynski M, Wolff JA, Breakefield XO, Gage FH. Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression. Science (New York, N.Y.). 242: 1575-8. PMID 3201248 DOI: 10.1126/Science.3201248  0.512
1988 Brundin P, Strecker RE, Gage FH, Lindvall O, Björklund A. Intracerebral transplantation of dopamine neurons: understanding the functional role of the mesolimbocortical dopamine system and developing a therapy for Parkinson's disease. Annals of the New York Academy of Sciences. 537: 148-60. PMID 3059921 DOI: 10.1111/J.1749-6632.1988.Tb42103.X  0.564
1988 Buzsaki G, Bickford R, Ponomareff G, Thal L, Mandel R, Gage F. Nucleus basalis and thalamic control of neocortical activity in the freely moving rat The Journal of Neuroscience. 8: 4007-4026. DOI: 10.1523/JNEUROSCI.08-11-04007.1988  0.343
1987 Fischer W, Wictorin K, Björklund A, Williams LR, Varon S, Gage FH. Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor. Nature. 329: 65-8. PMID 3627243 DOI: 10.1038/329065A0  0.755
1987 Nilsson OG, Shapiro ML, Gage FH, Olton DS, Björklund A. Spatial learning and memory following fimbria-fornix transection and grafting of fetal septal neurons to the hippocampus. Experimental Brain Research. 67: 195-215. PMID 3622677 DOI: 10.1007/BF00269466  0.692
1987 Gage FH, Buzsaki G, Nilsson O, Björklund A. Grafts of fetal cholinergic neurons to the deafferented hippocampus. Progress in Brain Research. 71: 335-47. PMID 3588952 DOI: 10.1016/S0079-6123(08)61835-X  0.52
1987 Varon S, Williams LR, Gage FH. Exogenous administration of neuronotrophic factors in vivo protects central nervous system neurons against axotomy induced degeneration. Progress in Brain Research. 71: 191-201. PMID 3588942 DOI: 10.1016/S0079-6123(08)61824-5  0.312
1987 Gage FH, Björklund A. Trophic and growth-regulating mechanisms in the central nervous system monitored by intracerebral neural transplants. Ciba Foundation Symposium. 126: 143-59. PMID 3556083 DOI: 10.1002/9780470513422.ch9  0.313
1987 Isacson O, Pritzel M, Dawbarn D, Brundin P, Kelly PA, Wiklund L, Emson PC, Gage FH, Dunnett SB, Björklund A. Striatal neural transplants in the ibotenic acid-lesioned rat neostriatum. Cellular and functional aspects. Annals of the New York Academy of Sciences. 495: 537-55. PMID 3474959 DOI: 10.1111/j.1749-6632.1987.tb23699.x  0.688
1987 Clarke DJ, Gage FH, Dunnett SB, Nilsson OG, Björklund A. Synaptogenesis of grafted cholinergic neurons. Annals of the New York Academy of Sciences. 495: 268-83. PMID 3474946 DOI: 10.1111/J.1749-6632.1987.Tb23680.X  0.693
1987 Peterson GM, Williams LR, Varon S, Gage FH. Loss of GABAergic neurons in medial septum after fimbria-fornix transection. Neuroscience Letters. 76: 140-4. PMID 3035435 DOI: 10.1016/0304-3940(87)90705-1  0.31
1987 Isacson O, Dawbarn D, Brundin P, Gage FH, Emson PC, Björklund A. Neural grafting in a rat model of Huntington's disease: striosomal-like organization of striatal grafts as revealed by acetylcholinesterase histochemistry, immunocytochemistry and receptor autoradiography. Neuroscience. 22: 481-97. PMID 2823174 DOI: 10.1016/0306-4522(87)90348-4  0.58
1986 Gage FH, Wictorin K, Fischer W, Williams LR, Varon S, Bjorklund A. Retrograde cell changes in medial septum and diagonal band following fimbria-fornix transection: quantitative temporal analysis. Neuroscience. 19: 241-55. PMID 3785665 DOI: 10.1016/0306-4522(86)90018-7  0.733
1986 Clarke DJ, Gage FH, Nilsson OG, Björklund A. Grafted septal neurons form cholinergic synaptic connections in the dentate gyrus of behaviorally impaired aged rats. The Journal of Comparative Neurology. 252: 483-92. PMID 3782513 DOI: 10.1002/cne.902520405  0.522
1986 Lindvall O, Ingvar M, Gage FH. Short term status epilepticus in rats causes specific behavioral impairments related to substantia nigra necrosis. Experimental Brain Research. 64: 143-8. PMID 3770107 DOI: 10.1007/BF00238210  0.449
1986 Williams LR, Varon S, Peterson GM, Wictorin K, Fischer W, Bjorklund A, Gage FH. Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection. Proceedings of the National Academy of Sciences of the United States of America. 83: 9231-5. PMID 3466184 DOI: 10.1073/Pnas.83.23.9231  0.763
1986 Brundin P, Isacson O, Gage FH, Prochiantz A, Björklund A. The rotating 6-hydroxydopamine-lesioned mouse as a model for assessing functional effects of neuronal grafting. Brain Research. 366: 346-9. PMID 3084035 DOI: 10.1016/0006-8993(86)91316-8  0.591
1986 Brundin P, Isacson O, Gage FH, Björklund A. Intrastriatal grafting of dopamine-containing neuronal cell suspensions: effects of mixing with target or non-target cells. Brain Research. 389: 77-84. PMID 3081240 DOI: 10.1016/0165-3806(86)90174-4  0.606
1986 Bengtsson F, Nobin A, Falck B, Gage FH, Jeppsson B. Portacaval shunt in the rat: selective alterations in behavior and brain serotonin. Pharmacology, Biochemistry, and Behavior. 24: 1611-6. PMID 2426719 DOI: 10.1016/0091-3057(86)90494-6  0.657
1986 Zetterström T, Brundin P, Gage FH, Sharp T, Isacson O, Dunnett SB, Ungerstedt U, Björklund A. In vivo measurement of spontaneous release and metabolism of dopamine from intrastriatal nigral grafts using intracerebral dialysis. Brain Research. 362: 344-9. PMID 2417666 DOI: 10.1016/0006-8993(86)90460-9  0.689
1985 Gage FH, Stenevi U, Carlstedt T, Foster G, Björklund A, Aguayo AJ. Anatomical and functional consequences of grafting mesencephalic neurons into a peripheral nerve "bridge" connected to the denervated striatum. Experimental Brain Research. 60: 584-9. PMID 4076379 DOI: 10.1007/Bf00236945  0.51
1985 Gage FH, Brundin P, Isacson O, Björklund A. Rat fetal brain tissue grafts survive and innervate host brain following five day pregraft tissue storage. Neuroscience Letters. 60: 133-7. PMID 4058805 DOI: 10.1016/0304-3940(85)90233-2  0.593
1985 Kelly PA, Gage FH, Ingvar M, Lindvall O, Stenevi U, Björklund A. Functional reactivation of the deafferented hippocampus by embryonic septal grafts as assessed by measurements of local glucose utilization. Experimental Brain Research. 58: 570-9. PMID 4007095 DOI: 10.1007/Bf00235873  0.598
1985 Brundin P, Nilsson OG, Gage FH, Björklund A. Cyclosporin A increases survival of cross-species intrastriatal grafts of embryonic dopamine-containing neurons. Experimental Brain Research. 60: 204-8. PMID 3930278 DOI: 10.1007/BF00237035  0.615
1985 Shapiro ML, Simon D, Olton DS, Gage FH, Bjorklund A, Stenevi U. Brain transplants: can they restore single unit activity in the hippocampus? Annals of the New York Academy of Sciences. 444: 536-7. PMID 3860121 DOI: 10.1111/J.1749-6632.1985.Tb37638.X  0.696
1985 Isacson O, Brundin P, Gage FH, Björklund A. Neural grafting in a rat model of Huntington's disease: progressive neurochemical changes after neostriatal ibotenate lesions and striatal tissue grafting. Neuroscience. 16: 799-817. PMID 2936982 DOI: 10.1016/0306-4522(85)90095-8  0.568
1985 Wieloch T, Lindvall O, Blomqvist P, Gage FH. Evidence for amelioration of ischaemic neuronal damage in the hippocampal formation by lesions of the perforant path. Neurological Research. 7: 24-6. PMID 2860584 DOI: 10.1080/01616412.1985.11739695  0.439
1985 Bengtsson F, Gage FH, Jeppsson B, Nobin A, Rosengren E. Brain monoamine metabolism and behavior in portacaval-shunted rats. Experimental Neurology. 90: 21-35. PMID 2412877 DOI: 10.1016/0014-4886(85)90037-8  0.558
1984 Gage FH, Dunnett SB, Björklund A. Spatial learning and motor deficits in aged rats. Neurobiology of Aging. 5: 43-8. PMID 6738785 DOI: 10.1016/0197-4580(84)90084-8  0.505
1984 Gage FH, Björklund A, Stenevi U. Cells of origin of the ventral cholinergic septohippocampal pathway undergoing compensatory collateral sprouting following fimbria-fornix transection. Neuroscience Letters. 44: 211-6. PMID 6709236 DOI: 10.1016/0304-3940(84)90083-1  0.515
1984 Gage FH, Björklund A, Stenevi U, Dunnett SB, Kelly PA. Intrahippocampal septal grafts ameliorate learning impairments in aged rats. Science (New York, N.Y.). 225: 533-6. PMID 6539949 DOI: 10.1126/science.6539949  0.672
1984 Dunnett SB, Bunch ST, Gage FH, Björklund A. Dopamine-rich transplants in rats with 6-OHDA lesions of the ventral tegmental area. I. Effects on spontaneous and drug-induced locomotor activity. Behavioural Brain Research. 13: 71-82. PMID 6477720 DOI: 10.1016/0166-4328(84)90031-7  0.504
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