| Year |
Citation |
Score |
| 2024 |
Gose T, Rasouli A, Dehghani-Ghahnaviyeh S, Wen PC, Wang Y, Lynch J, Fukuda Y, Shafi T, Ford RC, Tajkhorshid E, Schuetz JD. Tumor-acquired somatic mutation affects conformation to abolish ABCG2-mediated drug resistance. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 73: 101066. PMID 38387283 DOI: 10.1016/j.drup.2024.101066 |
0.304 |
|
| 2023 |
Gose T, Aitken HM, Wang Y, Lynch J, Rampersaud E, Fukuda Y, Wills M, Baril SA, Ford RC, Shelat A, Mara MLO, Schuetz JD. The net electrostatic potential and hydration of ABCG2 affect substrate transport. Nature Communications. 14: 5035. PMID 37596258 DOI: 10.1038/s41467-023-40610-5 |
0.711 |
|
| 2023 |
Baril SA, Gose T, Schuetz JD. How Cryo-EM Has Expanded Our Understanding of Membrane Transporters. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 51: 904-922. PMID 37438132 DOI: 10.1124/dmd.122.001004 |
0.333 |
|
| 2023 |
Lynch J, Wang Y, Li Y, Kavdia K, Fukuda Y, Ranjit S, Robinson CG, Grace CR, Xia Y, Peng J, Schuetz JD. A PPIX-binding probe facilitates discovery of PPIX-induced cell death modulation by peroxiredoxin. Communications Biology. 6: 673. PMID 37355765 DOI: 10.1038/s42003-023-05024-5 |
0.66 |
|
| 2021 |
Ganguly S, Finkelstein D, Shaw TI, Michalek RD, Zorn KM, Ekins S, Yasuda K, Fukuda Y, Schuetz JD, Mukherjee K, Schuetz EG. Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters. Plos One. 16: e0253852. PMID 34255797 DOI: 10.1371/journal.pone.0253852 |
0.678 |
|
| 2020 |
Donepudi AC, Smith GJ, Aladelokun O, Lee Y, Toro SJ, Pfohl M, Slitt AL, Wang L, Lee JY, Schuetz JD, Manautou JE. Lack of multidrug-resistance associated protein 4 prolongs partial hepatectomy-induced hepatic steatosis. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32142150 DOI: 10.1093/Toxsci/Kfaa032 |
0.336 |
|
| 2020 |
Gose T, Shafi T, Fukuda Y, Das S, Wang Y, Allcock A, Gavan McHarg A, Lynch J, Chen T, Tamai I, Shelat A, Ford RC, Schuetz JD. ABCG2 requires a single aromatic amino acid to "clamp" substrates and inhibitors into the binding pocket. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32067270 DOI: 10.1096/Fj.201902338Rr |
0.702 |
|
| 2020 |
Wijaya J, Vo BT, Liu J, Xu B, Wu G, Wang Y, Peng J, Zhang J, Janke LJ, Orr BA, Yu J, Roussel MF, Schuetz JD. An ABC transporter drives medulloblastoma pathogenesis by regulating Sonic Hedgehog signaling. Cancer Research. PMID 31948942 DOI: 10.1158/0008-5472.Can-19-2054 |
0.348 |
|
| 2020 |
Gose T, Shafi T, Fukuda Y, Das S, Wang Y, Lynch J, McHarg AG, Shelat A, Ford RC, Schuetz JD. A Single Amino Acid in ABCG2 is Essential for Clamping Substrates and Inhibitors into the Binding Pocket The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04943 |
0.66 |
|
| 2019 |
Ford RC, Marshall-Sabey D, Schuetz J. Linker Domains: Why ABC Transporters 'Live in Fragments no Longer'. Trends in Biochemical Sciences. PMID 31839525 DOI: 10.1016/J.Tibs.2019.11.004 |
0.395 |
|
| 2019 |
Donepudi AC, Goedken MJ, Schuetz JD, E Manautou J. Lack of multidrug resistance-associated protein 4 (Mrp4) alters the kinetics of acetaminophen toxicity. Toxicology Reports. 6: 841-849. PMID 31485416 DOI: 10.1016/J.Toxrep.2019.08.005 |
0.35 |
|
| 2019 |
O'Reilly C, Cho JH, Qi Q, Peters JL, Fukuda Y, Frase S, Peng J, Schuetz JD, Cheng Y, Yoon SO, Han MJ. Corrigendum to "Metabolic switching in pluripotent stem cells reorganizes energy metabolism and subcellular organelles" [379 (2019) 55-64]. Experimental Cell Research. PMID 31079852 DOI: 10.1016/J.Yexcr.2019.05.002 |
0.643 |
|
| 2019 |
O'Reilly C, Cho JH, Qi Q, Peters JL, Fukuda Y, Frase S, Peng J, Schuetz JD, Cheng Y, Yoon SO, Han MJ. Metabolic switching in pluripotent stem cells reorganizes energy metabolism and subcellular organelles. Experimental Cell Research. PMID 30922922 DOI: 10.1016/J.Yexcr.2019.03.028 |
0.677 |
|
| 2019 |
Gose T, Fukuda Y, Das S, Wang Y, Lynch J, Shelat A, Schuetz JD. Determining the Molecular Characteristics of How Ligands Interact with an ABC Transporter The Faseb Journal. 33. DOI: 10.1096/Fasebj.2019.33.1_Supplement.507.4 |
0.683 |
|
| 2019 |
Schuetz J. ABC efflux transporters and drug toxicity Drug Metabolism and Pharmacokinetics. 34: S6. DOI: 10.1016/J.Dmpk.2018.09.028 |
0.396 |
|
| 2018 |
Zoufal V, Mairinger S, Krohn M, Wanek T, Filip T, Sauberer M, Stanek J, Traxl A, Schuetz JD, Kuntner C, Pahnke J, Langer O. Influence of Multidrug Resistance-Associated Proteins on the Excretion of the ABCC1 Imaging Probe 6-Bromo-7-[C]Methylpurine in Mice. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 29942989 DOI: 10.1007/S11307-018-1230-Y |
0.3 |
|
| 2018 |
Crawford RR, Potukuchi PK, Schuetz EG, Schuetz JD. Beyond Competitive Inhibition: Regulation of ABC Transporters by Kinases and Protein-Protein Interactions as Potential Mechanisms of Drug-Drug Interactions. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29514827 DOI: 10.1124/Dmd.118.080663 |
0.415 |
|
| 2018 |
Su Y, Li X, Edwards H, Polin L, Kushner J, Dzinic SH, Hege K, Fukuda Y, Schuetz JD, Allen JE, Stogniew M, Prabhu VV, Taub JW, Lin H, Ge Y. Venetoclax Synergistically Enhances the Antileukemic Activity of Imipridone ONC213, a Novel Imipridone ONC201 Analog, in Acute Myeloid Leukemia Blood. 132: 3936-3936. DOI: 10.1182/Blood-2018-99-116997 |
0.687 |
|
| 2017 |
Boswell-Casteel RC, Fukuda Y, Schuetz JD. ABCB6, an ABC Transporter Impacting Drug Response and Disease. The Aaps Journal. 20: 8. PMID 29192381 DOI: 10.1208/S12248-017-0165-6 |
0.77 |
|
| 2017 |
Wijaya J, Fukuda Y, Schuetz JD. Obstacles to Brain Tumor Therapy: Key ABC Transporters. International Journal of Molecular Sciences. 18. PMID 29186899 DOI: 10.3390/Ijms18122544 |
0.689 |
|
| 2017 |
Nakanishi T, Ohno Y, Aotani R, Maruyama S, Shimada H, Kamo S, Oshima H, Oshima M, Schuetz JD, Tamai I. A novel role for OATP2A1/SLCO2A1 in a murine model of colon cancer. Scientific Reports. 7: 16567. PMID 29185482 DOI: 10.1038/S41598-017-16738-Y |
0.32 |
|
| 2017 |
Pitre A, Ge Y, Lin W, Wang Y, Fukuda Y, Temirov J, Phillips AH, Peters JL, Fan Y, Ma J, Nourse A, Sinha C, Lin H, Kriwacki R, Downing JR, ... ... Schuetz JD, et al. An unexpected protein interaction promotes drug resistance in leukemia. Nature Communications. 8: 1547. PMID 29146910 DOI: 10.1038/S41467-017-01678-Y |
0.702 |
|
| 2017 |
Ellis JL, Bove KE, Schuetz EG, Leino D, Valencia CA, Schuetz JD, Miethke A, Yin C. Zebrafish abcb11b mutant reveals novel strategies to restore bile excretion impaired by bile salt export pump deficiency. Hepatology (Baltimore, Md.). PMID 29091294 DOI: 10.1002/Hep.29632 |
0.392 |
|
| 2017 |
Fukuda Y, Wang Y, Lian S, Lynch J, Nagai S, Fanshawe B, Kandilci A, Janke LJ, Neale G, Fan Y, Sorrentino BP, Roussel MF, Grosveld G, Schuetz JD. Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis. Jci Insight. 2. PMID 28768907 DOI: 10.1172/Jci.Insight.92409 |
0.7 |
|
| 2017 |
Murray J, Valli E, Yu DMT, Truong AM, Gifford AJ, Eden GL, Gamble LD, Hanssen KM, Flemming CL, Tan A, Tivnan A, Allan S, Saletta F, Cheung L, Ruhle M, ... Schuetz JD, et al. Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo. European Journal of Cancer (Oxford, England : 1990). 83: 132-141. PMID 28735070 DOI: 10.1016/J.Ejca.2017.06.024 |
0.43 |
|
| 2017 |
Liu C, Janke LJ, Yang JJ, Evans WE, Schuetz JD, Relling MV. Differential effects of thiopurine methyltransferase (TPMT) and multidrug resistance-associated protein gene 4 (MRP4) on mercaptopurine toxicity. Cancer Chemotherapy and Pharmacology. PMID 28623449 DOI: 10.1007/S00280-017-3361-2 |
0.331 |
|
| 2017 |
Kanamitsu K, Kusuhara H, Schuetz JD, Takeuchi K, Sugiyama Y. Investigation of the Importance of Multidrug Resistance-associated Protein 4 (Mrp4/Abcc4) in the Active Efflux of Anionic Drugs Across the Blood-brain Barrier. Journal of Pharmaceutical Sciences. PMID 28456721 DOI: 10.1016/J.Xphs.2017.04.040 |
0.38 |
|
| 2017 |
Schuetz JD. A novel plasma membrane porphyrin transporter that affects porphyria Drug Metabolism and Pharmacokinetics. 32: S14. DOI: 10.1016/J.Dmpk.2016.10.067 |
0.356 |
|
| 2016 |
Fukuda Y, Cheong PL, Lynch J, Brighton C, Frase S, Kargas V, Rampersaud E, Wang Y, Sankaran VG, Yu B, Ney PA, Weiss MJ, Vogel P, Bond PJ, Ford RC, ... ... Schuetz JD, et al. The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6. Nature Communications. 7: 12353. PMID 27507172 DOI: 10.1038/Ncomms12353 |
0.709 |
|
| 2016 |
Drenberg CD, Hu S, Li L, Buelow DR, Orwick SJ, Gibson AA, Schuetz JD, Sparreboom A, Baker SD. ABCC4 Is a Determinant of Cytarabine-Induced Cytotoxicity and Myelosuppression. Clinical and Translational Science. PMID 26842729 DOI: 10.1111/Cts.12366 |
0.443 |
|
| 2015 |
Morgan JA, Lynch J, Panetta JC, Wang Y, Frase S, Bao J, Zheng J, Opferman JT, Janke L, Green DM, Chemaitilly W, Schuetz JD. Apoptosome activation, an important molecular instigator in 6-mercaptopurine induced Leydig cell death. Scientific Reports. 5: 16488. PMID 26576726 DOI: 10.1038/Srep16488 |
0.35 |
|
| 2015 |
Cheepala SB, Pitre A, Fukuda Y, Takenaka K, Zhang Y, Wang Y, Frase S, Pestina T, Gartner TK, Jackson C, Schuetz JD. ABCC4, a plasma membrane transporter modulating platelet aggregation. Blood. PMID 26405223 DOI: 10.1182/Blood-2014-08-595942 |
0.68 |
|
| 2015 |
Morfouace M, Cheepala S, Jackson S, Fukuda Y, Patel YT, Fatima S, Kawauchi D, Shelat AA, Stewart CF, Sorrentino BP, Schuetz JD, Roussel MF. ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy. Cancer Research. PMID 26199091 DOI: 10.1158/0008-5472.Can-15-0030 |
0.728 |
|
| 2015 |
Sinha C, Ren A, Arora K, Moon CS, Yarlagadda S, Woodrooffe K, Lin S, Schuetz JD, Ziady AG, Naren AP. PKA and actin play critical roles as downstream effectors in MRP4-mediated regulation of fibroblast migration. Cellular Signalling. 27: 1345-55. PMID 25841995 DOI: 10.1016/J.Cellsig.2015.03.022 |
0.376 |
|
| 2015 |
Schuetz JD, Ishikawa T. ABC transporters and cancer. Preface. Advances in Cancer Research. 125: xv-xvii. PMID 25640273 DOI: 10.1016/S0065-230X(15)00010-X |
0.348 |
|
| 2015 |
Fukuda Y, Lian S, Schuetz JD. Leukemia and ABC Transporters Advances in Cancer Research. 125: 171-196. PMID 25640270 DOI: 10.1016/Bs.Acr.2014.10.006 |
0.735 |
|
| 2015 |
Li-Harms X, Milasta S, Lynch J, Wright C, Joshi A, Iyengar R, Neale G, Wang X, Wang YD, Prolla TA, Thompson JE, Opferman JT, Green DR, Schuetz J, Kundu M. Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice. Blood. 125: 162-74. PMID 25411424 DOI: 10.1182/Blood-2014-07-586396 |
0.303 |
|
| 2015 |
Fukuda Y, Wang Y, Nagai S, Fanshawe B, Kandilci A, Zindy F, Janke L, Neale G, Fan Y, Sorrentino B, Roussel M, Grosveld G, Schuetz J. The heme biosynthetic pathway plays a crucial role in N-MYC myeloid leukemias Experimental Hematology. 43: S63. DOI: 10.1016/J.Exphem.2015.06.124 |
0.649 |
|
| 2014 |
Demetz E, Schroll A, Auer K, Heim C, Patsch JR, Eller P, Theurl M, Theurl I, Theurl M, Seifert M, Lener D, Stanzl U, Haschka D, Asshoff M, Dichtl S, ... ... Schuetz JD, et al. The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism. Cell Metabolism. 20: 787-98. PMID 25444678 DOI: 10.1016/J.Cmet.2014.09.004 |
0.325 |
|
| 2014 |
Jin D, Ni TT, Sun J, Wan H, Amack JD, Yu G, Fleming J, Chiang C, Li W, Papierniak A, Cheepala S, Conseil G, Cole SP, Zhou B, Drummond IA, ... Schuetz JD, et al. Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport. Nature Cell Biology. 16: 841-51. PMID 25173977 DOI: 10.1038/Ncb3029 |
0.372 |
|
| 2014 |
Schuetz JD, Swaan PW, Tweedie DJ. The role of transporters in toxicity and disease Drug Metabolism and Disposition. 42: 541-545. PMID 24598705 DOI: 10.1124/Dmd.114.057539 |
0.434 |
|
| 2014 |
Murphy AJ, Sarrazy V, Wang N, Bijl N, Abramowicz S, Westerterp M, Welch CB, Schuetz JD, Yvan-Charvet L. Deficiency of ATP-binding cassette transporter B6 in megakaryocyte progenitors accelerates atherosclerosis in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 751-8. PMID 24504733 DOI: 10.1161/ATVBAHA.113.302613 |
0.415 |
|
| 2013 |
Haslam IS, Pitre A, Schuetz JD, Paus R. Protection against chemotherapy-induced alopecia: targeting ATP-binding cassette transporters in the hair follicle? Trends in Pharmacological Sciences. 34: 599-604. PMID 24100054 DOI: 10.1016/J.Tips.2013.09.001 |
0.369 |
|
| 2013 |
Furmanski BD, Hu S, Fujita K, Li L, Gibson AA, Janke LJ, Williams RT, Schuetz JD, Sparreboom A, Baker SD. Contribution of ABCC4-mediated gastric transport to the absorption and efficacy of dasatinib. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4359-70. PMID 23794731 DOI: 10.1158/1078-0432.Ccr-13-0980 |
0.402 |
|
| 2013 |
Fukuda Y, Takenaka K, Sparreboom A, Cheepala SB, Wu CP, Ekins S, Ambudkar SV, Schuetz JD. Human immunodeficiency virus protease inhibitors interact with ATP binding cassette transporter 4/multidrug resistance protein 4: a basis for unanticipated enhanced cytotoxicity. Molecular Pharmacology. 84: 361-71. PMID 23775562 DOI: 10.1124/Mol.113.086967 |
0.709 |
|
| 2013 |
Cheepala SB, Bao J, Nachagari D, Sun D, Wang Y, Zhong TP, Zhong T, Naren AP, Zheng J, Schuetz JD. Crucial role for phylogenetically conserved cytoplasmic loop 3 in ABCC4 protein expression. The Journal of Biological Chemistry. 288: 22207-18. PMID 23766510 DOI: 10.1074/Jbc.M113.476218 |
0.388 |
|
| 2013 |
Sinha C, Ren A, Arora K, Moon CS, Yarlagadda S, Zhang W, Cheepala SB, Schuetz JD, Naren AP. Multi-drug resistance protein 4 (MRP4)-mediated regulation of fibroblast cell migration reflects a dichotomous role of intracellular cyclic nucleotides. The Journal of Biological Chemistry. 288: 3786-94. PMID 23264633 DOI: 10.1074/Jbc.M112.435925 |
0.432 |
|
| 2013 |
Cheepala S, Hulot JS, Morgan JA, Sassi Y, Zhang W, Naren AP, Schuetz JD. Cyclic nucleotide compartmentalization: contributions of phosphodiesterases and ATP-binding cassette transporters. Annual Review of Pharmacology and Toxicology. 53: 231-53. PMID 23072381 DOI: 10.1146/Annurev-Pharmtox-010611-134609 |
0.472 |
|
| 2013 |
Treanor LM, Zhou S, Fukuda Y, Satish N, Finkelstein D, Schuetz JD, Mullighan CG, Sorrentino BP. N-Myc Is Overexpressed In Both Murine and Human Early T-Cell Precursor Leukemia and Is Sufficient To Initiate this Leukemia In Multipotent Primitive Arf-/- thymocytes Blood. 122: 348-348. DOI: 10.1182/Blood.V122.21.348.348 |
0.682 |
|
| 2013 |
Lian SL, WANG Y, Zhou S, Sukthankar M, Neale GA, Downing JR, Schuetz JD. A Role For a Multi-Drug Resistance Protein (MRP4/ABCC4) In Pediatric Acute Myeloid Leukemia (AML) Blood. 122: 2518-2518. DOI: 10.1182/Blood.V122.21.2518.2518 |
0.406 |
|
| 2012 |
Zhang Y, Li F, Patterson AD, Wang Y, Krausz KW, Neale G, Thomas S, Nachagari D, Vogel P, Vore M, Gonzalez FJ, Schuetz JD. Abcb11 deficiency induces cholestasis coupled to impaired β-fatty acid oxidation in mice. The Journal of Biological Chemistry. 287: 24784-94. PMID 22619174 DOI: 10.1074/Jbc.M111.329318 |
0.333 |
|
| 2012 |
Perciavalle RM, Stewart DP, Koss B, Lynch J, Milasta S, Bathina M, Temirov J, Cleland MM, Pelletier S, Schuetz JD, Youle RJ, Green DR, Opferman JT. Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration Nature Cell Biology. 14: 575-583. PMID 22544066 DOI: 10.1038/Ncb2488 |
0.341 |
|
| 2012 |
Morgan JA, Cheepala SB, Wang Y, Neale G, Adachi M, Nachagari D, Leggas M, Zhao W, Boyd K, Venkataramanan R, Schuetz JD. Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice. The Journal of Biological Chemistry. 287: 14456-66. PMID 22375007 DOI: 10.1074/Jbc.M111.319681 |
0.351 |
|
| 2012 |
Ulrich DL, Lynch J, Wang Y, Fukuda Y, Nachagari D, Du G, Sun D, Fan Y, Tsurkan L, Potter PM, Rehg JE, Schuetz JD. ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity. The Journal of Biological Chemistry. 287: 12679-90. PMID 22294697 DOI: 10.1074/Jbc.M111.336180 |
0.717 |
|
| 2012 |
Fukuda Y, Schuetz JD. ABC transporters and their role in nucleoside and nucleotide drug resistance Biochemical Pharmacology. 83: 1073-1083. PMID 22285911 DOI: 10.1016/J.Bcp.2011.12.042 |
0.712 |
|
| 2012 |
Cheepala SB, Takenaka K, Pestina TI, Jackson CW, Schuetz JD. The Role of ABC Transporter Abcc4 in Platelets Physiologic Function and Its Impact On Collagen Meditated Platelet Aggregation Blood. 120: 1063-1063. DOI: 10.1182/Blood.V120.21.1063.1063 |
0.301 |
|
| 2011 |
Nagai S, Takenaka K, Nachagari D, Rose C, Domoney K, Sun D, Sparreboom A, Schuetz JD. Deoxycytidine kinase modulates the impact of the ABC transporter ABCG2 on clofarabine cytotoxicity. Cancer Research. 71: 1781-91. PMID 21245102 DOI: 10.1158/0008-5472.Can-10-1919 |
0.435 |
|
| 2011 |
Fukuda Y, Aguilar-Bryan L, Vaxillaire M, Dechaume A, Wang Y, Dean M, Moitra K, Bryan J, Schuetz JD. Conserved intramolecular disulfide bond is critical to trafficking and fate of ATP-binding cassette (ABC) transporters ABCB6 and sulfonylurea receptor 1 (SUR1)/ABCC8. The Journal of Biological Chemistry. 286: 8481-92. PMID 21199866 DOI: 10.1074/Jbc.M110.174516 |
0.715 |
|
| 2011 |
Krishnamurthy P, Schuetz JD. The role of ABCG2 and ABCB6 in porphyrin metabolism and cell survival. Current Pharmaceutical Biotechnology. 12: 647-55. PMID 21118089 DOI: 10.2174/138920111795163995 |
0.475 |
|
| 2010 |
Li C, Schuetz JD, Naren AP. Tobacco carcinogen NNK transporter MRP2 regulates CFTR function in lung epithelia: implications for lung cancer. Cancer Letters. 292: 246-53. PMID 20089353 DOI: 10.1016/J.Canlet.2009.12.009 |
0.301 |
|
| 2010 |
Furmanski BD, Fujita K, Lie L, Orwick S, Potukuchi P, Schuetz JD, Sparreboom A, Baker SD. Abstract 1528: Abcc4 (Mrp4)-deficiency leads to decreased oral absorption of dasatinib Cancer Research. 70: 1528-1528. DOI: 10.1158/1538-7445.Am10-1528 |
0.362 |
|
| 2009 |
Lynch J, Fukuda Y, Krishnamurthy P, Du G, Schuetz JD. Cell survival under stress is enhanced by a mitochondrial ATP-binding cassette transporter that regulates hemoproteins. Cancer Research. 69: 5560-7. PMID 19549895 DOI: 10.1158/0008-5472.Can-09-0078 |
0.719 |
|
| 2009 |
van de Ven R, de Groot J, Reurs AW, Wijnands PG, van de Wetering K, Schuetz JD, de Gruijl TD, Scheper RJ, Scheffer GL. Unimpaired immune functions in the absence of Mrp4 (Abcc4). Immunology Letters. 124: 81-7. PMID 19406153 DOI: 10.1016/J.Imlet.2009.04.007 |
0.336 |
|
| 2009 |
Ose A, Ito M, Kusuhara H, Yamatsugu K, Kanai M, Shibasaki M, Hosokawa M, Schuetz JD, Sugiyama Y. Limited brain distribution of [3R,4R,5S]-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate phosphate (Ro 64-0802), a pharmacologically active form of oseltamivir, by active efflux across the blood-brain barrier mediated by organic anion transporter 3 (Oat3/Slc22a8) and multidrug resistance-associated protein 4 (Mrp4/Abcc4). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 315-21. PMID 19029202 DOI: 10.1124/Dmd.108.024018 |
0.378 |
|
| 2009 |
Schuetz JD. Role in ABC transporters in liver functions and disease Toxicology Letters. 189: S18. DOI: 10.1016/J.Toxlet.2009.06.012 |
0.358 |
|
| 2008 |
Kitamura Y, Hirouchi M, Kusuhara H, Schuetz JD, Sugiyama Y. Increasing systemic exposure of methotrexate by active efflux mediated by multidrug resistance-associated protein 3 (Mrp3/Abcc3) Journal of Pharmacology and Experimental Therapeutics. 327: 465-473. PMID 18719291 DOI: 10.1124/Jpet.108.140475 |
0.336 |
|
| 2008 |
Krishnamurthy P, Schwab M, Takenaka K, Nachagari D, Morgan J, Leslie M, Du W, Boyd K, Cheok M, Nakauchi H, Marzolini C, Kim RB, Poonkuzhali B, Schuetz E, Evans W, ... ... Schuetz JD, et al. Transporter-mediated protection against thiopurine-induced hematopoietic toxicity. Cancer Research. 68: 4983-9. PMID 18593894 DOI: 10.1158/0008-5472.Can-07-6790 |
0.407 |
|
| 2008 |
Matsushima S, Maeda K, Hayashi H, Debori Y, Schinkel AH, Schuetz JD, Kusuhara H, Sugiyama Y. Involvement of multiple efflux transporters in hepatic disposition of fexofenadine. Molecular Pharmacology. 73: 1474-83. PMID 18245269 DOI: 10.1124/Mol.107.041459 |
0.408 |
|
| 2007 |
Li C, Krishnamurthy PC, Penmatsa H, Marrs KL, Wang XQ, Zaccolo M, Jalink K, Li M, Nelson DJ, Schuetz JD, Naren AP. Spatiotemporal coupling of cAMP transporter to CFTR chloride channel function in the gut epithelia. Cell. 131: 940-51. PMID 18045536 DOI: 10.1016/J.Cell.2007.09.037 |
0.396 |
|
| 2007 |
Yamada A, Maeda K, Kamiyama E, Sugiyama D, Kondo T, Shiroyanagi Y, Nakazawa H, Okano T, Adachi M, Schuetz JD, Adachi Y, Hu Z, Kusuhara H, Sugiyama Y. Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 2166-76. PMID 17823233 DOI: 10.1124/Dmd.107.017459 |
0.46 |
|
| 2007 |
Mizuno N, Takahashi T, Kusuhara H, Schuetz JD, Niwa T, Sugiyama Y. Evaluation of the role of breast cancer resistance protein (BCRP/ABCG2) and multidrug resistance-associated protein 4 (MRP4/ABCC4) in the urinary excretion of sulfate and glucuronide metabolites of edaravone (MCI-186; 3-methyl-1-phenyl-2-pyrazolin-5-one). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 2045-52. PMID 17682070 DOI: 10.1124/Dmd.107.016352 |
0.392 |
|
| 2007 |
Takenaka K, Morgan JA, Scheffer GL, Adachi M, Stewart CF, Sun D, Leggas M, Ejendal KF, Hrycyna CA, Schuetz JD. Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution. Cancer Research. 67: 6965-72. PMID 17638908 DOI: 10.1158/0008-5472.Can-06-4720 |
0.457 |
|
| 2007 |
Marzolini C, Tirona RG, Gervasini G, Poonkuzhali B, Assem M, Lee W, Leake BF, Schuetz JD, Schuetz EG, Kim RB. A common polymorphism in the bile acid receptor farnesoid X receptor is associated with decreased hepatic target gene expression. Molecular Endocrinology (Baltimore, Md.). 21: 1769-80. PMID 17519356 DOI: 10.1210/Me.2007-0025 |
0.333 |
|
| 2007 |
Krishnamurthy P, Xie T, Schuetz JD. The role of transporters in cellular heme and porphyrin homeostasis. Pharmacology & Therapeutics. 114: 345-58. PMID 17368550 DOI: 10.1016/J.Pharmthera.2007.02.001 |
0.408 |
|
| 2007 |
Ci L, Kusuhara H, Adachi M, Schuetz JD, Takeuchi K, Sugiyama Y. Involvement of MRP4 (ABCC4) in the luminal efflux of ceftizoxime and cefazolin in the kidney. Molecular Pharmacology. 71: 1591-7. PMID 17344354 DOI: 10.1124/Mol.106.031823 |
0.378 |
|
| 2007 |
de Wolf CJ, Yamaguchi H, van der Heijden I, Wielinga PR, Hundscheid SL, Ono N, Scheffer GL, de Haas M, Schuetz JD, Wijnholds J, Borst P. cGMP transport by vesicles from human and mouse erythrocytes. The Febs Journal. 274: 439-50. PMID 17229149 DOI: 10.1111/J.1742-4658.2006.05591.X |
0.433 |
|
| 2007 |
Hasegawa M, Kusuhara H, Adachi M, Schuetz JD, Takeuchi K, Sugiyama Y. Multidrug resistance-associated protein 4 is involved in the urinary excretion of hydrochlorothiazide and furosemide. Journal of the American Society of Nephrology : Jasn. 18: 37-45. PMID 17135398 DOI: 10.1681/Asn.2005090966 |
0.414 |
|
| 2007 |
Imaoka T, Kusuhara H, Adachi M, Schuetz JD, Takeuchi K, Sugiyama Y. Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir. Molecular Pharmacology. 71: 619-27. PMID 17110501 DOI: 10.1124/Mol.106.028233 |
0.385 |
|
| 2007 |
Hu S, Niu H, Orwick S, Rubnitz J, Schuetz J, Baker SD. Preclinical Evaluation of Sorafenib in Combination with Cytarabine and Clofarabine in Acute Myeloid Leukemia (AML). Blood. 110: 4202-4202. DOI: 10.1182/Blood.V110.11.4202.4202 |
0.347 |
|
| 2006 |
Turriziani O, Pagnotti P, Pierangeli A, Focher F, Baranello C, Bellomi F, Falasca F, Morgan J, Schuetz JD, Antonelli G. The effects of prolonged treatment with zidovudine, lamivudine, and abacavir on a T-lymphoblastoid cell line. Aids Research and Human Retroviruses. 22: 960-7. PMID 17067265 DOI: 10.1089/Aid.2006.22.960 |
0.348 |
|
| 2006 |
Kleemann P, Casper B, Huber M, Schuetz JD, Lohoff M. Multidrug-resistance-associated protein 1 (Mrp1) is probably not required for murine Th cell activation International Immunology. 18: 1603-1606. PMID 17008412 DOI: 10.1093/Intimm/Dxl094 |
0.317 |
|
| 2006 |
Krishnamurthy PC, Du G, Fukuda Y, Sun D, Sampath J, Mercer KE, Wang J, Sosa-Pineda B, Murti KG, Schuetz JD. Identification of a mammalian mitochondrial porphyrin transporter. Nature. 443: 586-9. PMID 17006453 DOI: 10.1038/Nature05125 |
0.721 |
|
| 2006 |
Lamba JK, Chen X, Lan LB, Kim JW, Wei Wang X, Relling MV, Kazuto Y, Watkins PB, Strom S, Sun D, Schuetz JD, Schuetz EG. Increased CYP3A4 copy number in TONG/HCC cells but not in DNA from other humans. Pharmacogenetics and Genomics. 16: 415-27. PMID 16708050 DOI: 10.1097/01.Fpc.0000194421.35641.70 |
0.321 |
|
| 2006 |
Leggas M, Panetta JC, Zhuang Y, Schuetz JD, Johnston B, Bai F, Sorrentino B, Zhou S, Houghton PJ, Stewart CF. Gefitinib modulates the function of multiple ATP-binding cassette transporters in vivo. Cancer Research. 66: 4802-7. PMID 16651435 DOI: 10.1158/0008-5472.Can-05-2915 |
0.459 |
|
| 2006 |
Mennone A, Soroka CJ, Cai SY, Harry K, Adachi M, Hagey L, Schuetz JD, Boyer JL. Mrp4-/- mice have an impaired cytoprotective response in obstructive cholestasis. Hepatology (Baltimore, Md.). 43: 1013-21. PMID 16628672 DOI: 10.1002/Hep.21158 |
0.321 |
|
| 2006 |
Krishnamurthy P, Schuetz JD. Role of ABCG2/BCRP in biology and medicine. Annual Review of Pharmacology and Toxicology. 46: 381-410. PMID 16402910 DOI: 10.1146/annurev.pharmtox.46.120604.141238 |
0.359 |
|
| 2006 |
Johnson BM, Zhang P, Schuetz JD, Brouwer KL. Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 556-62. PMID 16204465 DOI: 10.1124/Dmd.105.005793 |
0.413 |
|
| 2005 |
Krishnamurthy P, Schuetz JD. The ABC transporter Abcg2/Bcrp: role in hypoxia mediated survival. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 18: 349-58. PMID 16158227 DOI: 10.1007/S10534-005-3709-7 |
0.445 |
|
| 2005 |
Masson D, Lagrost L, Athias A, Gambert P, Brimer-Cline C, Lan L, Schuetz JD, Schuetz EG, Assem M. Expression of the pregnane X receptor in mice antagonizes the cholic acid-mediated changes in plasma lipoprotein profile Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 2164-2169. PMID 16123326 DOI: 10.1161/01.Atv.0000183674.88817.Fb |
0.306 |
|
| 2005 |
Ozvegy-Laczka C, Várady G, Köblös G, Ujhelly O, Cervenak J, Schuetz JD, Sorrentino BP, Koomen GJ, Váradi A, Német K, Sarkadi B. Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface. The Journal of Biological Chemistry. 280: 4219-27. PMID 15557326 DOI: 10.1074/Jbc.M411338200 |
0.389 |
|
| 2004 |
Stewart CF, Leggas M, Schuetz JD, Panetta JC, Cheshire PJ, Peterson J, Daw N, Jenkins JJ, Gilbertson R, Germain GS, Harwood FC, Houghton PJ. Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice. Cancer Research. 64: 7491-9. PMID 15492275 DOI: 10.1158/0008-5472.Can-04-0096 |
0.362 |
|
| 2004 |
Leggas M, Adachi M, Scheffer GL, Sun D, Wielinga P, Du G, Mercer KE, Zhuang Y, Panetta JC, Johnston B, Scheper RJ, Stewart CF, Schuetz JD. Mrp4 confers resistance to topotecan and protects the brain from chemotherapy. Molecular and Cellular Biology. 24: 7612-21. PMID 15314169 DOI: 10.1128/Mcb.24.17.7612-7621.2004 |
0.399 |
|
| 2004 |
Zhang Y, Schuetz JD, Elmquist WF, Miller DW. Plasma membrane localization of multidrug resistance-associated protein homologs in brain capillary endothelial cells. The Journal of Pharmacology and Experimental Therapeutics. 311: 449-55. PMID 15218051 DOI: 10.1124/Jpet.104.068528 |
0.332 |
|
| 2004 |
Ozvegy-Laczka C, Hegedus T, Várady G, Ujhelly O, Schuetz JD, Váradi A, Kéri G, Orfi L, Német K, Sarkadi B. High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter. Molecular Pharmacology. 65: 1485-95. PMID 15155841 DOI: 10.1124/Mol.65.6.1485 |
0.439 |
|
| 2004 |
Houghton PJ, Germain GS, Harwood FC, Schuetz JD, Stewart CF, Buchdunger E, Traxler P. Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro. Cancer Research. 64: 2333-7. PMID 15059881 DOI: 10.1158/0008-5472.Can-03-3344 |
0.388 |
|
| 2004 |
Krishnamurthy P, Ross DD, Nakanishi T, Bailey-Dell K, Zhou S, Mercer KE, Sarkadi B, Sorrentino BP, Schuetz JD. The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme. The Journal of Biological Chemistry. 279: 24218-25. PMID 15044468 DOI: 10.1074/Jbc.M313599200 |
0.387 |
|
| 2004 |
Denk GU, Soroka CJ, Takeyama Y, Chen WS, Schuetz JD, Boyer JL. Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat Journal of Hepatology. 40: 585-591. PMID 15030973 DOI: 10.1016/J.Jhep.2003.12.001 |
0.36 |
|
| 2004 |
Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD. Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. The Journal of Biological Chemistry. 279: 22250-7. PMID 15004017 DOI: 10.1074/Jbc.M314111200 |
0.409 |
|
| 2004 |
Wagner M, Fickert P, Zollner G, Silbert D, Fuchsbichler A, Gumhold J, Schuetz J, Gonzalez F, Zatloukal K, Marschall H, Denk H, Trauner M. 73 Adaptive renal ABC transporter expression in common bile duct-ligated mice Journal of Hepatology. 40: 26. DOI: 10.1016/S0168-8278(04)90073-6 |
0.353 |
|
| 2003 |
Wagner M, Fickert P, Zollner G, Fuchsbichler A, Silbert D, Tsybrovskyy O, Zatloukal K, Guo GL, Schuetz JD, Gonzalez FJ, Marschall HU, Denk H, Trauner M. Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice. Gastroenterology. 125: 825-38. PMID 12949728 DOI: 10.1016/S0016-5085(03)01068-0 |
0.362 |
|
| 2003 |
Wierdl M, Wall A, Morton CL, Sampath J, Danks MK, Schuetz JD, Potter PM. Carboxylesterase-mediated sensitization of human tumor cells to CPT-11 cannot override ABCG2-mediated drug resistance. Molecular Pharmacology. 64: 279-88. PMID 12869632 DOI: 10.1124/Mol.64.2.279 |
0.398 |
|
| 2003 |
Zamber CP, Lamba JK, Yasuda K, Farnum J, Thummel K, Schuetz JD, Schuetz EG. Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine. Pharmacogenetics. 13: 19-28. PMID 12544509 DOI: 10.1097/00008571-200301000-00004 |
0.313 |
|
| 2003 |
Wierdl M, Morton CL, Harris LC, Danks MK, Schuetz JD, Potter PM. p53-mediated regulation of expression of a rabbit liver carboxylesterase confers sensitivity to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11). The Journal of Pharmacology and Experimental Therapeutics. 304: 699-705. PMID 12538824 DOI: 10.1124/Jpet.102.044149 |
0.348 |
|
| 2003 |
Zelcer N, Reid G, Wielinga P, Kuil A, van der Heijden I, Schuetz JD, Borst P. Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4). The Biochemical Journal. 371: 361-7. PMID 12523936 DOI: 10.1042/Bj20021886 |
0.457 |
|
| 2003 |
Lamba JK, Adachi M, Sun D, Tammur J, Schuetz EG, Allikmets R, Schuetz JD. Nonsense mediated decay downregulates conserved alternatively spliced ABCC4 transcripts bearing nonsense codons. Human Molecular Genetics. 12: 99-109. PMID 12499391 DOI: 10.1093/Hmg/Ddg011 |
0.409 |
|
| 2003 |
WAGNER M, FICKERT P, FUCHSBICHLER A, SILBERT D, GUMHOLD J, ZOLLNER G, ZATLOUKAL K, MARSCHALL H, SCHUETZ J, GONZALEZ F. 1106 Hepatic and renal ABC transporter expression as critical determinants of ursodeoxycholic acid-induced bile infarcts in bile duct-ligated mice Hepatology. 38: 688-689. DOI: 10.1016/S0270-9139(03)81144-8 |
0.354 |
|
| 2002 |
Wielinga PR, Reid G, Challa EE, van der Heijden I, van Deemter L, de Haas M, Mol C, Kuil AJ, Groeneveld E, Schuetz JD, Brouwer C, De Abreu RA, Wijnholds J, Beijnen JH, Borst P. Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells. Molecular Pharmacology. 62: 1321-31. PMID 12435799 DOI: 10.1124/Mol.62.6.1321 |
0.451 |
|
| 2002 |
Adachi M, Reid G, Schuetz JD. Therapeutic and biological importance of getting nucleotides out of cells: A case for the ABC transporters, MRP4 and 5 Advanced Drug Delivery Reviews. 54: 1333-1342. PMID 12406648 DOI: 10.1016/S0169-409X(02)00166-7 |
0.364 |
|
| 2002 |
Yasuda K, Lan LB, Sanglard D, Furuya K, Schuetz JD, Schuetz EG. Interaction of cytochrome P450 3A inhibitors with P-glycoprotein Journal of Pharmacology and Experimental Therapeutics. 303: 323-332. PMID 12235267 DOI: 10.1124/Jpet.102.037549 |
0.378 |
|
| 2002 |
Zhou S, Morris JJ, Barnes Y, Lan L, Schuetz JD, Sorrentino BP. Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo. Proceedings of the National Academy of Sciences of the United States of America. 99: 12339-44. PMID 12218177 DOI: 10.1073/Pnas.192276999 |
0.379 |
|
| 2002 |
Turriziani O, Schuetz JD, Focher F, Scagnolari C, Sampath J, Adachi M, Bambacioni F, Riva E, Antonelli G. Impaired 2',3'-dideoxy-3'-thiacytidine accumulation in T-lymphoblastoid cells as a mechanism of acquired resistance independent of multidrug resistant protein 4 with a possible role for ATP-binding cassette C11. The Biochemical Journal. 368: 325-32. PMID 12133003 DOI: 10.1042/Bj20020494 |
0.374 |
|
| 2002 |
Adachi M, Sampath J, Lan LB, Sun D, Hargrove P, Flatley R, Tatum A, Edwards MZ, Wezeman M, Matherly L, Drake R, Schuetz J. Expression of MRP4 confers resistance to ganciclovir and compromises bystander cell killing. The Journal of Biological Chemistry. 277: 38998-9004. PMID 12105214 DOI: 10.1074/Jbc.M203262200 |
0.401 |
|
| 2002 |
Ekins S, Kim RB, Leake BF, Dantzig AH, Schuetz EG, Lan LB, Yasuda K, Shepard RL, Winter MA, Schuetz JD, Wikel JH, Wrighton SA. Application of three-dimensional quantitative structure-activity relationships of P-glycoprotein inhibitors and substrates. Molecular Pharmacology. 61: 974-81. PMID 11961114 DOI: 10.1124/Mol.61.5.974 |
0.309 |
|
| 2002 |
Ekins S, Kim RB, Leake BF, Dantzig AH, Schuetz EG, Lan LB, Yasuda K, Shepard RL, Winter MA, Schuetz JD, Wikel JH, Wrighton SA. Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein. Molecular Pharmacology. 61: 964-73. PMID 11961113 DOI: 10.1124/Mol.61.5.964 |
0.348 |
|
| 2002 |
Emadi-Konjin HP, Zhang H, Anandan V, Sun D, Schuetz J, Furuya KN. Isolation of a genomic clone containing the promoter region of the human ATP binding cassette (ABC) transporter, ABCB6 Biochimica Et Biophysica Acta - Gene Structure and Expression. 1574: 117-130. PMID 11955620 DOI: 10.1016/S0167-4781(01)00340-2 |
0.351 |
|
| 2002 |
Sampath J, Adachi M, Hatse S, Naesens L, Balzarini J, Flatley RM, Matherly LH, Schuetz JD. Role of MRP4 and MRP5 in biology and chemotherapy Aaps Pharmsci. 4. DOI: 10.1208/Ps040314 |
0.482 |
|
| 2001 |
Zhou S, Schuetz JD, Bunting KD, Colapietro AM, Sampath J, Morris JJ, Lagutina I, Grosveld GC, Osawa M, Nakauchi H, Sorrentino BP. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nature Medicine. 7: 1028-34. PMID 11533706 DOI: 10.1038/Nm0901-1028 |
0.363 |
|
| 2001 |
Schuetz EG, Strom S, Yasuda K, Lecureur V, Assem M, Brimer C, Lamba J, Kim RB, Ramachandran V, Komoroski BJ, Venkataramanan R, Cai H, Sinal CJ, Gonzalez FJ, Schuetz JD. Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450. The Journal of Biological Chemistry. 276: 39411-8. PMID 11509573 DOI: 10.1074/Jbc.M106340200 |
0.359 |
|
| 2001 |
Kim RB, Leake BF, Choo EF, Dresser GK, Kubba SV, Schwarz UI, Taylor A, Xie HG, McKinsey J, Zhou S, Lan LB, Schuetz JD, Schuetz EG, Wilkinson GR. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clinical Pharmacology and Therapeutics. 70: 189-99. PMID 11503014 DOI: 10.1067/Mcp.2001.117412 |
0.312 |
|
| 2001 |
Sampath J, Sun D, Kidd VJ, Grenet J, Gandhi A, Shapiro LH, Wang Q, Zambetti GP, Schuetz JD. Mutant p53 Cooperates with ETS and Selectively Up-regulates Human MDR1 Not MRP1 Journal of Biological Chemistry. 276: 39359-39367. PMID 11483599 DOI: 10.1074/Jbc.M103429200 |
0.331 |
|
| 2001 |
Tammur J, Prades C, Arnould I, Rzhetsky A, Hutchinson A, Adachi M, Schuetz JD, Swoboda KJ, Ptácek LJ, Rosier M, Dean M, Allikmets R. Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12. Gene. 273: 89-96. PMID 11483364 DOI: 10.1016/S0378-1119(01)00572-8 |
0.353 |
|
| 2001 |
Lecureur V, Thottassery JV, Sun D, Schuetz EG, Lahti J, Zambetti GP, Schuetz JD. Mdr1b facilitates p53-mediated cell death and p53 is required for Mdr1b upregulation in vivo Oncogene. 20: 303-313. PMID 11313959 DOI: 10.1038/Sj.Onc.1204065 |
0.314 |
|
| 2001 |
Kuehl P, Zhang J, Lin Y, Lamba J, Assem M, Schuetz J, Watkins PB, Daly A, Wrighton SA, Hall SD, Maurel P, Relling M, Brimer C, Yasuda K, Venkataramanan R, et al. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nature Genetics. 27: 383-91. PMID 11279519 DOI: 10.1038/86882 |
0.324 |
|
| 2001 |
Ding BC, Whetstine JR, Witt TL, Schuetz JD, Matherly LH. Repression of human reduced folate carrier gene expression by wild type p53. The Journal of Biological Chemistry. 276: 8713-9. PMID 11106643 DOI: 10.1074/Jbc.M005248200 |
0.326 |
|
| 2000 |
Brimer C, Dalton JT, Zhu Z, Schuetz J, Yasuda K, Vanin E, Relling MV, Lu Y, Schuetz EG. Creation of polarized cells coexpressing CYP3A4, NADPH cytochrome P450 reductase and MDR1/P-glycoprotein Pharmaceutical Research. 17: 803-810. PMID 10990198 DOI: 10.1023/A:1007599923694 |
0.418 |
|
| 1999 |
Schuetz JD, Connelly MC, Sun D, Paibir SG, Flynn PM, Srinivas RV, Kumar A, Fridland A. MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs. Nature Medicine. 5: 1048-51. PMID 10470083 DOI: 10.1038/12487 |
0.364 |
|
| 1999 |
Belkov VM, Krynetski EY, Schuetz JD, Yanishevski Y, Masson E, Mathew S, Raimondi S, Pui C, Relling MV, Evans WE. Reduced Folate Carrier Expression in Acute Lymphoblastic Leukemia: A Mechanism for Ploidy but not Lineage Differences in Methotrexate Accumulation Blood. 93: 1643-1650. DOI: 10.1182/Blood.V93.5.1643 |
0.301 |
|
| 1998 |
Lutterbach B, Sun D, Schuetz J, Hiebert SW. The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein Molecular and Cellular Biology. 18: 3604-3611. PMID 9584201 DOI: 10.1128/Mcb.18.6.3604 |
0.327 |
|
| 1998 |
Schuetz EG, Yasuda K, Arimori K, Schuetz JD. Human MDR1 and mouse mdr1a P-glycoprotein alter the cellular retention and disposition of erythromycin, but not of retinoic acid or benzo(a)pyrene Archives of Biochemistry and Biophysics. 350: 340-347. PMID 9473310 DOI: 10.1006/Abbi.1997.0537 |
0.383 |
|
| 1997 |
Thottassery JV, Zambettii GP, Arimori K, Schuetz EG, Schuetz JD. p53-dependent regulation of MDR1 gene expression causes selective resistance to chemotherapeutic agents Proceedings of the National Academy of Sciences of the United States of America. 94: 11037-11042. PMID 9380755 DOI: 10.1073/Pnas.94.20.11037 |
0.353 |
|
| 1997 |
Krynetski EY, Tai HL, Yates CR, Fessing MY, Loennechen T, Schuetz JD, Relling MV, Evans WE. Genetic polymorphism of thiopurine S-methyltransferase: clinical importance and molecular mechanisms. Pharmacogenetics. 6: 279-90. PMID 8873214 DOI: 10.1097/00008571-199608000-00001 |
0.312 |
|
| 1996 |
Strom SC, Pisarov LA, Dorko K, Thompson MT, Schuetz JD, Schuetz EG. Use of human hepatocytes to study P450 gene induction Methods in Enzymology. 272: 388-401. PMID 8791798 DOI: 10.1016/S0076-6879(96)72044-X |
0.326 |
|
| 1996 |
Schuetz EG, Schinkel AH, Relling MV, Schuetz JD. P-glycoprotein: A major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans Proceedings of the National Academy of Sciences of the United States of America. 93: 4001-4005. PMID 8633005 DOI: 10.1073/Pnas.93.9.4001 |
0.389 |
|
| 1995 |
Krynetski EY, Schuetz JD, Galpin AJ, Pui CH, Relling MV, Evans WE. A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 92: 949-53. PMID 7862671 DOI: 10.1073/Pnas.92.4.949 |
0.306 |
|
| 1995 |
Schuetz EG, Schuetz JD, Thompson MT, Fisher RA, Madariage JR, Strom SC. Phenotypic variability in induction of P-glycoprotein mRNA by aromatic hydrocarbons in primary human hepatocytes Molecular Carcinogenesis. 12: 61-65. PMID 7662117 DOI: 10.1002/Mc.2940120202 |
0.317 |
|
| 1995 |
Schuetz JD, Strom SC, Schuetz EG. Induction of P-glycoprotein mRNA by protein synthesis inhibition is not controlled by a transcriptional repressor protein in rat and human liver cells Journal of Cellular Physiology. 165: 261-272. PMID 7593204 DOI: 10.1002/Jcp.1041650207 |
0.321 |
|
| 1992 |
Kolars JC, Schmiedlin-Ren P, Schuetz JD, Fang C, Watkins PB. Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes Journal of Clinical Investigation. 90: 1871-1878. PMID 1430211 DOI: 10.1172/Jci116064 |
0.352 |
|
| 1992 |
Burger HJ, Schuetz JD, Schuetz EG, Guzelian PS. Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16α-carbonitrile: Analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes Proceedings of the National Academy of Sciences of the United States of America. 89: 2145-2149. PMID 1372436 DOI: 10.1073/Pnas.89.6.2145 |
0.314 |
|
| 1989 |
Schuetz JD, Molowa DT, Guzelian PS. Characterization of a cDNA encoding a new member of the glucocorticoid-responsive cytochromes P450 in human liver Archives of Biochemistry and Biophysics. 274: 355-365. PMID 2802615 DOI: 10.1016/0003-9861(89)90449-9 |
0.32 |
|
| 1989 |
Matherly LH, Schuetz JD, Westin E, Goldman ID. A method for the synchronization of cultured cells with aphidicolin: Application to the large-scale synchronization of L1210 cells and the study of the cell cycle regulation of thymidylate synthase and dihydrofolate reductase Analytical Biochemistry. 182: 338-345. PMID 2514611 DOI: 10.1016/0003-2697(89)90605-2 |
0.308 |
|
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