Year |
Citation |
Score |
2020 |
Baker GJ, Muhlich JL, Palaniappan SK, Moore JK, Davis SH, Santagata S, Sorger PK. SYLARAS: A Platform for the Statistical Analysis and Visual Display of Systemic Immunoprofiling Data and Its Application to Glioblastoma. Cell Systems. PMID 32898474 DOI: 10.1016/J.Cels.2020.08.001 |
0.321 |
|
2020 |
Touat M, Li YY, Boynton AN, Spurr LF, Iorgulescu JB, Bohrson CL, Cortes-Ciriano I, Birzu C, Geduldig JE, Pelton K, Lim-Fat MJ, Pal S, Ferrer-Luna R, Ramkissoon SH, Dubois F, ... ... Santagata S, et al. Mechanisms and therapeutic implications of hypermutation in gliomas. Nature. 580: 517-523. PMID 32322066 DOI: 10.1038/S41586-020-2209-9 |
0.365 |
|
2020 |
Rozenblatt-Rosen O, Regev A, Oberdoerffer P, Nawy T, Hupalowska A, Rood JE, Ashenberg O, Cerami E, Coffey RJ, Demir E, Ding L, Esplin ED, Ford JM, Goecks J, Ghosh S, ... ... Santagata S, et al. The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution. Cell. 181: 236-249. PMID 32302568 DOI: 10.1016/J.Cell.2020.03.053 |
0.348 |
|
2020 |
Guerra SL, Maertens O, Kuzmickas R, De Raedt T, Adeyemi RO, Guild CJ, Guillemette S, Redig AJ, Chambers ES, Xu M, Tiv H, Santagata S, Jänne PA, Elledge SJ, Cichowski K. A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers. Cancer Cell. PMID 32243838 DOI: 10.1016/J.Ccell.2020.03.004 |
0.339 |
|
2020 |
Shih DJH, Nayyar N, Bihun I, Dagogo-Jack I, Gill CM, Aquilanti E, Bertalan M, Kaplan A, D'Andrea MR, Chukwueke U, Ippen FM, Alvarez-Breckenridge C, Camarda ND, Lastrapes M, McCabe D, ... ... Santagata S, et al. Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma. Nature Genetics. PMID 32203465 DOI: 10.1038/S41588-020-0592-7 |
0.315 |
|
2020 |
Heaphy CM, Bi WL, Coy S, Davis C, Gallia GL, Santagata S, Rodriguez FJ. Telomere length alterations and ATRX/DAXX loss in pituitary adenomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 32203094 DOI: 10.1038/S41379-020-0523-2 |
0.327 |
|
2020 |
Färkkilä A, Gulhan DC, Casado J, Jacobson CA, Nguyen H, Kochupurakkal B, Maliga Z, Yapp C, Chen YA, Schapiro D, Zhou Y, Graham JR, Dezube BJ, Munster P, Santagata S, et al. Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer. Nature Communications. 11: 1459. PMID 32193378 DOI: 10.1038/S41467-020-15315-8 |
0.305 |
|
2020 |
Guerriero JL, Mehta AK, Cheney EM, Castrillon JA, Lin J, Taveira MdO, Sonzogni O, Pantelidou C, Hartl CA, Oldham WM, Johnson NT, Boswell SA, Kalocsay M, Berberich MJ, Mei S, ... ... Santagata S, et al. Abstract P5-04-01: PARP inhibition modulates the infiltration, phenotype and function of tumor-associated macrophages (TAMs) in BRCA-associated breast cancer and can be augmented by harnessing the anti-tumor potential of TAMs Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P5-04-01 |
0.318 |
|
2020 |
Pastorello RG, Lin J, Du Z, Mei S, Taneja K, Dillon DA, Schnitt SJ, Sorger PK, Mittendorf EA, Santagata S, Guerriero JL. Abstract P5-02-03: Highly multiplexed tissue-based cyclic immunofluorescence in breast cancer for precision oncology Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P5-02-03 |
0.313 |
|
2019 |
Randall EC, Lopez BGC, Peng S, Regan MS, Abdelmoula WM, Basu SS, Santagata S, Yoon H, Haigis M, Agar JN, Tran NL, Elmquist WF, White FM, Sarkaria JN, Agar NYR. Localized metabolomic gradients in patient-derived xenograft models of glioblastoma. Cancer Research. PMID 31767628 DOI: 10.1158/0008-5472.Can-19-0638 |
0.345 |
|
2019 |
Jaeger AM, Stopfer L, Lee S, Gaglia G, Sandel D, Santagata S, Lin NU, Trepel JB, White FM, Jacks T, Lindquist S, Whitesell L. Rebalancing protein homeostasis enhances tumor antigen presentation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31213460 DOI: 10.1158/1078-0432.Ccr-19-0596 |
0.342 |
|
2019 |
Coy S, Rashid R, Stemmer-Rachamimov A, Santagata S. An update on the CNS manifestations of neurofibromatosis type 2. Acta Neuropathologica. PMID 31161239 DOI: 10.1007/S00401-019-02029-5 |
0.305 |
|
2019 |
Tsvetkov P, Detappe A, Cai K, Keys HR, Brune Z, Ying W, Thiru P, Reidy M, Kugener G, Rossen J, Kocak M, Kory N, Tsherniak A, Santagata S, Whitesell L, et al. Mitochondrial metabolism promotes adaptation to proteotoxic stress. Nature Chemical Biology. PMID 31133756 DOI: 10.1038/S41589-019-0291-9 |
0.31 |
|
2019 |
Nathenson M, Hemming ML, Malik K, Lin J, Santagata S, Du Z, Marino-Enriquez A, Hagan TJ, Chipashvili O, Thornton KA, Raut CP, Childs BH, Bertagnolli MM, Sicinska E, Ku N, et al. Molecular characterization and management of secondary resistance to serial TRK inhibitors. Journal of Clinical Oncology. 37: e22547-e22547. DOI: 10.1200/Jco.2019.37.15_Suppl.E22547 |
0.307 |
|
2019 |
Farkkila A, Lin JR, Casado J, Nguyen H, Zhou Y, Graham JR, Dezube BJ, Waggoner S, Munster P, Fleming GF, Santagata S, Matulonis UA, Sorger PK, Swisher EM, D’Andrea AD, et al. Abstract 4487: Association of the tumor-immune microenvironment with response to niraparib and pembrolizumab in relapsed, platinum-resistant ovarian cancer Cancer Research. 79: 4487-4487. DOI: 10.1158/1538-7445.Am2019-4487 |
0.36 |
|
2019 |
Touat M, Li Y, Boynton A, Spurr L, Iorgulescu B, Birzu C, Pal S, Ferrer-Luna R, Geduldig J, Bellamy C, Younan N, Baldini C, Verreault M, Guillerm E, Ammari S, ... ... Santagata S, et al. DRES-08. CLINICAL SIGNIFICANCE OF HYPERMUTATION IN GLIOMAS Neuro-Oncology. 21: vi73-vi73. DOI: 10.1093/Neuonc/Noz175.296 |
0.349 |
|
2019 |
Touat M, Li Y, Boynton A, Spurr L, Iorglescu B, Geduldig J, Birzu C, Lim Fat M, Santagata S, Coulet F, Beuvon F, Mokhtari K, Giry M, Block S, Guillerm E, et al. OS9.1 Clinical significance of hypermutation in gliomas Neuro-Oncology. 21: iii18-iii18. DOI: 10.1093/Neuonc/Noz126.059 |
0.345 |
|
2018 |
Fritchie K, Jensch K, Moskalev EA, Caron A, Jenkins S, Link M, Brown PD, Rodriguez FJ, Guajardo A, Brat D, Velázquez Vega JE, Perry A, Wu A, Raleigh DR, Santagata S, et al. The impact of histopathology and NAB2-STAT6 fusion subtype in classification and grading of meningeal solitary fibrous tumor/hemangiopericytoma. Acta Neuropathologica. PMID 30584643 DOI: 10.1007/S00401-018-1952-6 |
0.329 |
|
2018 |
Walpole S, Pritchard AL, Cebulla CM, Pilarski R, Stautberg M, Davidorf FH, de la Fouchardière A, Cabaret O, Golmard L, Stoppa-Lyonnet D, Garfield E, Njauw CN, Cheung M, Turunen JA, Repo P, ... ... Santagata S, et al. Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide. Journal of the National Cancer Institute. PMID 30517737 DOI: 10.1093/Jnci/Djy171 |
0.344 |
|
2018 |
Aquilanti E, Miller J, Santagata S, Cahill DP, Brastianos PK. Updates in prognostic markers for gliomas. Neuro-Oncology. 20: vii17-vii26. PMID 30412261 DOI: 10.1093/Neuonc/Noy158 |
0.377 |
|
2018 |
Venur VA, Santagata S, Galanis E, Brastianos PK. New molecular targets in meningiomas: the present and the future. Current Opinion in Neurology. 31: 740-746. PMID 30379704 DOI: 10.1097/Wco.0000000000000615 |
0.309 |
|
2018 |
Clark AR, Calligaris D, Regan MS, Pomeranz Krummel D, Agar JN, Kallay L, MacDonald T, Schniederjan M, Santagata S, Pomeroy SL, Agar NYR, Sengupta S. Rapid discrimination of pediatric brain tumors by mass spectrometry imaging. Journal of Neuro-Oncology. PMID 30128689 DOI: 10.1007/S11060-018-2978-2 |
0.337 |
|
2018 |
Juratli TA, McCabe D, Nayyar N, Williams EA, Silverman IM, Tummala SS, Fink AL, Baig A, Martinez-Lage M, Selig MK, Bihun IV, Shankar GM, Penson T, Lastrapes M, Daubner D, ... ... Santagata S, et al. DMD genomic deletions characterize a subset of progressive/higher-grade meningiomas with poor outcome. Acta Neuropathologica. PMID 30123936 DOI: 10.1007/S00401-018-1899-7 |
0.352 |
|
2018 |
Sorger PK, Lin JR, Izar B, Wang S, Yapp C, Mei S, Shah PM, Santagata S. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. Elife. 7. PMID 29993362 DOI: 10.7554/Elife.31657 |
0.313 |
|
2018 |
Du Z, Brewster R, Merrill PH, Chmielecki J, Francis J, Aizer A, Abedalthagafi M, Sholl LM, Geffers L, Alexander B, Santagata S. Meningioma transcription factors link cell lineage with systemic metabolic cues. Neuro-Oncology. PMID 29660031 DOI: 10.1093/Neuonc/Noy057 |
0.301 |
|
2018 |
Farkkila A, Chopra SS, Lin J, Maliga Z, Koruchupakkal B, Strickland KC, Howitt BE, Santagata S, Matulonis UA, Elias K, Swisher EM, Konstantinopoulos PA, Sorger P, D'Andrea AD. Abstract 139: DNA damage and immunoprofiling with highly multiplexed tissue immunofluorescence (t-CycIF) in high-grade serous ovarian cancer Cancer Research. 78: 139-139. DOI: 10.1158/1538-7445.Am2018-139 |
0.343 |
|
2018 |
Fritchie K, Jensch K, Jenkins S, Link M, D Brown P, Rodriguez F, Guajardo A, Brat D, Velazquez Vega J, Perry A, Wu A, Raleigh D, Santagata S, Louis D, Brastianos P, et al. RARE-08. GRADING CONSIDERATIONS FOR MENINGEAL SOLITARY FIBROUS TUMOR/HEMANGIOPERICYTOMA Neuro-Oncology. 20: vi237-vi238. DOI: 10.1093/Neuonc/Noy148.985 |
0.318 |
|
2017 |
Coroller TP, Bi WL, Huynh E, Abedalthagafi M, Aizer AA, Greenwald NF, Parmar C, Narayan V, Wu WW, Miranda de Moura S, Gupta S, Beroukhim R, Wen PY, Al-Mefty O, Dunn IF, ... Santagata S, et al. Radiographic prediction of meningioma grade by semantic and radiomic features. Plos One. 12: e0187908. PMID 29145421 DOI: 10.1371/Journal.Pone.0187908 |
0.314 |
|
2017 |
Mei Y, Du Z, Hu C, Greenwald NF, Abedalthagafi M, Agar NYR, Dunn GP, Bi WL, Santagata S, Dunn IF. Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling. Cell Communication and Signaling : Ccs. 15: 34. PMID 28923059 DOI: 10.1186/S12964-017-0189-7 |
0.324 |
|
2017 |
Coy S, Dubuc AM, Dahiya S, Ligon KL, Vasiljevic A, Santagata S. Nuclear CRX and FOXJ1 Expression Differentiates Non-Germ Cell Pineal Region Tumors and Supports the Ependymal Differentiation of Papillary Tumor of the Pineal Region. The American Journal of Surgical Pathology. PMID 28719464 DOI: 10.1097/Pas.0000000000000903 |
0.334 |
|
2017 |
Bi WL, Greenwald NF, Abedalthagafi M, Wala J, Gibson WJ, Agarwalla PK, Horowitz P, Schumacher SE, Esaulova E, Mei Y, Chevalier A, Ducar M, Thorner AR, van Hummelen P, Stemmer-Rachamimov A, ... ... Santagata S, et al. Genomic landscape of high-grade meningiomas. Npj Genomic Medicine. 2. PMID 28713588 DOI: 10.1038/S41525-017-0014-7 |
0.373 |
|
2017 |
Bi WL, Greenwald NF, Ramkissoon SH, Abedalthagafi M, Coy SM, Ligon KL, Mei Y, MacConaill L, Ducar M, Min L, Santagata S, Kaiser UB, Beroukhim R, Laws ER, Dunn IF. Clinical identification of oncogenic drivers and copy number alterations in pituitary tumors. Endocrinology. PMID 28486603 DOI: 10.1210/En.2016-1967 |
0.378 |
|
2017 |
Shankar GM, Santagata S. BAP1 mutations in high-grade meningioma: implications for patient care. Neuro-Oncology. PMID 28482042 DOI: 10.1093/Neuonc/Nox094 |
0.403 |
|
2017 |
Ramkissoon SH, Bandopadhayay P, Hwang J, Ramkissoon LA, Greenwald NF, Schumacher SE, O'Rourke R, Pinches N, Ho P, Malkin H, Sinai C, Filbin M, Plant A, Bi WL, Chang MS, ... ... Santagata S, et al. Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors. Neuro-Oncology. PMID 28104717 DOI: 10.1093/Neuonc/Now294 |
0.309 |
|
2017 |
Tsvetkov P, Sokol E, Jin D, Gupta P, Santagata S, Whitesell L, Lindquist S. Abstract A28: Targeting the epigenetic state regulating cancer cell vulnerability to proteasome inhibition Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Pmccavuln16-A28 |
0.31 |
|
2017 |
Linda Bi W, Greenwald N, Dubuc A, Santagata S, Ligon K, Ligon A, MacConnail L, Beroukhim R, Dunn I. PATH-30. GENOMIC LANDSCAPE OF CENTRAL NERVOUS SYSTEM TUMORS Neuro-Oncology. 19: vi177-vi177. DOI: 10.1093/Neuonc/Nox168.720 |
0.313 |
|
2017 |
Bandopadhayay P, Ramkissoon S, Hwang J, Ramkissoon L, Greenwald N, Schumacher S, O’Rourke R, Pinches N, Ho P, Malkin H, Sinai C, Filbin M, Plant A, Bi W, Chang M, ... ... Santagata S, et al. GENE-09. PRECISION MEDICINE ANALYSIS OF 203 PEDIATRIC BRAIN TUMORS REVEALS CLINICALLY RELEVANT GENOMIC ALTERATIONS Neuro-Oncology. 19: iv20-iv20. DOI: 10.1093/Neuonc/Nox083.080 |
0.338 |
|
2017 |
Brastianos PK, Alvarez-Breckenridge C, Miller JJ, Nayyar N, Gill C, Dias-Santagata D, Santagata S, Multani P, Yip S, Cahill D, Iafrate AJ, Batchelor T. OS06.4 Identification of novel NTRK fusion in glioneuronal tumors and radiographic response following therapy with an NTRK inhibitor Neuro-Oncology. 19: iii11-iii11. DOI: 10.1093/Neuonc/Nox036.038 |
0.31 |
|
2016 |
Fogh SE, Johnson DR, Barker FG, Brastianos PK, Clarke JL, Kaufmann TJ, Oberndorfer S, Preusser M, Raghunathan A, Santagata S, Theodosopoulos PV. : meningioma. Neuro-Oncology Practice. 3: 120-134. PMID 31386096 DOI: 10.1093/Nop/Npv063 |
0.309 |
|
2016 |
Shankar GM, Abedalthagafi M, Vaubel RA, Merrill PH, Nayyar N, Gill CM, Brewster R, Bi WL, Agarwalla PK, Thorner AR, Reardon DA, Al-Mefty O, Wen PY, Alexander BM, van Hummelen P, ... ... Santagata S, et al. Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas. Neuro-Oncology. PMID 28170043 DOI: 10.1093/Neuonc/Now235 |
0.386 |
|
2016 |
Coroller T, Bi W, Abedalthagafi M, Aizer A, Wu W, Greenwald N, Beroukhim R, Al-Mefty O, Santagata S, Dunn I, Alexander B, Huang R, Aerts H. SU-D-207B-02: Early Grade Classification in Meningioma Patients Combining Radiomics and Semantics Data. Medical Physics. 43: 3348-3349. PMID 28048264 DOI: 10.1118/1.4955670 |
0.319 |
|
2016 |
Tsvetkov P, Sokol E, Jin D, Brune Z, Thiru P, Ghandi M, Garraway LA, Gupta PB, Santagata S, Whitesell L, Lindquist S. Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers. Proceedings of the National Academy of Sciences of the United States of America. PMID 28028240 DOI: 10.1073/Pnas.1619067114 |
0.321 |
|
2016 |
Robinson LC, Santagata S, Hankinson TC. Potential evolution of neurosurgical treatment paradigms for craniopharyngioma based on genomic and transcriptomic characteristics. Neurosurgical Focus. 41: E3. PMID 27903126 DOI: 10.3171/2016.9.Focus16308 |
0.381 |
|
2016 |
Martinez-Gutierrez JC, D'Andrea MR, Cahill DP, Santagata S, Barker FG, Brastianos PK. Diagnosis and management of craniopharyngiomas in the era of genomics and targeted therapy. Neurosurgical Focus. 41: E2. PMID 27903124 DOI: 10.3171/2016.9.Focus16325 |
0.336 |
|
2016 |
Strickland MR, Gill CM, Nayyar N, D'Andrea MR, Thiede C, Juratli TA, Schackert G, Borger DR, Santagata S, Frosch MP, Cahill DP, Brastianos PK, Barker FG. Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas. Journal of Neurosurgery. 1-7. PMID 27885953 DOI: 10.3171/2016.8.Jns161076 |
0.352 |
|
2016 |
Dagogo-Jack I, Gill CM, Cahill DP, Santagata S, Brastianos PK. Treatment of brain metastases in the modern genomic era. Pharmacology & Therapeutics. PMID 27773784 DOI: 10.1016/J.Pharmthera.2016.10.011 |
0.34 |
|
2016 |
Bi WL, Horowtiz P, Greenwald N, Abedalthagafi M, Agarwalla PK, Gibson WJ, Mei Y, Schumacher SE, Ben-David U, Chevalier A, Carter SL, Tiao G, Brastianos PK, Ligon AH, Ducar M, ... ... Santagata S, et al. Landscape of genomic alterations in pituitary adenomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27707790 DOI: 10.1158/1078-0432.Ccr-16-0790 |
0.322 |
|
2016 |
Coy S, Du Z, Sheu SH, Woo T, Rodriguez FJ, Kieran MW, Santagata S. Distinct patterns of primary and motile cilia in Rathke's cleft cysts and craniopharyngioma subtypes. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 27562488 DOI: 10.1038/Modpathol.2016.153 |
0.301 |
|
2016 |
Lu FK, Calligaris D, Olubiyi OI, Norton I, Yang W, Santagata S, Xie XS, Golby AJ, Agar NY. Label-Free Neurosurgical Pathology with Stimulated Raman Imaging. Cancer Research. PMID 27197198 DOI: 10.1158/0008-5472.Can-16-0270 |
0.344 |
|
2016 |
Bandopadhayay P, Ramkissoon LA, Jain P, Bergthold G, Wala J, Zeid R, Schumacher SE, Urbanski L, O'Rourke R, Gibson WJ, Pelton K, Ramkissoon SH, Han HJ, Zhu Y, Choudhari N, ... ... Santagata S, et al. MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. Nature Genetics. PMID 26829751 DOI: 10.1038/Ng.3500 |
0.358 |
|
2016 |
Abedalthagafi M, Bi WL, Aizer AA, Merrill PH, Brewster R, Agarwalla PK, Listewnik ML, Dias-Santagata D, Thorner AR, Van Hummelen P, Brastianos PK, Reardon DA, Wen PY, Al-Mefty O, Ramkissoon SH, ... ... Santagata S, et al. Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma. Neuro-Oncology. PMID 26826201 DOI: 10.1093/Neuonc/Nov316 |
0.333 |
|
2016 |
Bi WL, Abedalthagafi M, Horowitz P, Agarwalla PK, Mei Y, Aizer AA, Brewster R, Dunn GP, Al-Mefty O, Alexander BM, Santagata S, Beroukhim R, Dunn IF. Genomic landscape of intracranial meningiomas. Journal of Neurosurgery. 1-11. PMID 26771848 DOI: 10.3171/2015.6.Jns15591 |
0.338 |
|
2016 |
Brastianos PK, Shankar GM, Gill CM, Taylor-Weiner A, Nayyar N, Panka DJ, Sullivan RJ, Frederick DT, Abedalthagafi M, Jones PS, Dunn IF, Nahed BV, Romero JM, Louis DN, Getz G, ... ... Santagata S, et al. Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy. Journal of the National Cancer Institute. 108. PMID 26498373 DOI: 10.1093/Jnci/Djv310 |
0.33 |
|
2015 |
Brastianos PK, Santagata S. ENDOCRINE TUMOURS: BRAF V600E mutations in papillary craniopharyngioma. European Journal of Endocrinology / European Federation of Endocrine Societies. PMID 26563980 DOI: 10.1530/Eje-15-0957 |
0.396 |
|
2015 |
Brastianos PK, Carter SL, Santagata S, Cahill DP, Taylor-Weiner A, Jones RT, Van Allen EM, Lawrence MS, Horowitz PM, Cibulskis K, Ligon KL, Tabernero J, Seoane J, Martinez-Saez E, Curry WT, et al. Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. Cancer Discovery. PMID 26410082 DOI: 10.1158/2159-8290.Cd-15-0369 |
0.325 |
|
2015 |
Tsvetkov P, Mendillo ML, Zhao J, Carette JE, Merrill PH, Cikes D, Varadarajan M, van Diemen FR, Penninger JM, Goldberg AL, Brummelkamp TR, Santagata S, Lindquist S. Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome. Elife. 4. PMID 26327695 DOI: 10.7554/Elife.08467 |
0.311 |
|
2015 |
Abedalthagafi MS, Bi WL, Merrill PH, Gibson WJ, Rose MF, Du Z, Francis JM, Du R, Dunn IF, Ligon AH, Beroukhim R, Santagata S. ARID1A and TERT promoter mutations in dedifferentiated meningioma. Cancer Genetics. 208: 345-50. PMID 25963524 DOI: 10.1016/J.Cancergen.2015.03.005 |
0.382 |
|
2015 |
Bergthold G, Bandopadhayay P, Hoshida Y, Ramkissoon S, Ramkissoon L, Rich B, Maire CL, Paolella BR, Schumacher SE, Tabak B, Ferrer-Luna R, Ozek M, Sav A, Santagata S, Wen PY, et al. Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype. Neuro-Oncology. PMID 25825052 DOI: 10.1093/Neuonc/Nov045 |
0.359 |
|
2015 |
Ramkissoon SH, Bi WL, Schumacher SE, Ramkissoon LA, Haidar S, Knoff D, Dubuc A, Brown L, Burns M, Cryan JB, Abedalthagafi M, Kang YJ, Schultz N, Reardon DA, Lee EQ, ... ... Santagata S, et al. Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma. Neuro-Oncology. PMID 25754088 DOI: 10.1093/Neuonc/Nov015 |
0.318 |
|
2015 |
Du Z, Abedalthagafi M, Aizer AA, McHenry AR, Sun HH, Bray MA, Viramontes O, Machaidze R, Brastianos PK, Reardon DA, Dunn IF, Freeman GJ, Ligon KL, Carpenter AE, Alexander BM, ... ... Santagata S, et al. Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma. Oncotarget. 6: 4704-16. PMID 25609200 DOI: 10.18632/Oncotarget.3082 |
0.301 |
|
2015 |
Brastianos PK, Carter SL, Santagata S, Taylor-Weiner A, Jones RT, Allen EV, Ligon KL, Tabernero J, Seoane J, Martinez-Saez E, Cahill D, Curry WT, Dunn IF, Paek SH, Hummelen PV, et al. Abstract 4727: Genomic characterization of brain metastases reveals divergent evolution and metastasis specific mutations Brain. 75: 4727-4727. DOI: 10.1158/1538-7445.Am2015-4727 |
0.326 |
|
2015 |
Nigim F, Rabkin SD, Brastianos P, Ramesh V, Cahill D, Santagata S, Martuza RL, Wakimoto H. MNGO-16ESTABLISHMENT OF A PATIENT - DERIVED ORTHOTOPIC MALIGNANT MENINGIOMA MODEL FOR THE DEVELOPMENT OF TARGETED THERAPY Neuro-Oncology. 17: v133.2-v133. DOI: 10.1093/Neuonc/Nov220.15 |
0.376 |
|
2015 |
Bi WL, Horowitz P, Agarwalla PK, Abedalthagafi M, Gibson WJ, Santagata S, Laws ER, Beroukhim R, Dunn IF. GENO-09LANDSCAPE OF GENOMIC ALTERATIONS IN PITUITARY ADENOMAS Neuro-Oncology. 17: v93.1-v93. DOI: 10.1093/Neuonc/Nov215.09 |
0.369 |
|
2015 |
Linda Bi W, Abedalthagafi M, Mei Y, Alexander B, Beroukhim R, Ligon A, Santagata S, Al-Mefty O, Dunn I. Genetic Alterations in Skull Base Meningiomas Journal of Neurological Surgery Part B: Skull Base. 76. DOI: 10.1055/S-0035-1546562 |
0.325 |
|
2015 |
Brastianos P, Carter S, Santagata S, Cahill D, Taylor-Weiner A, Jones R, Ligon K, Tabernero J, Seoane J, Martinez Saez E, Johnson B, Choueiri T, Stemmer-Rachamimov A, Lin N, Beroukhim R, et al. 2905 Genomic characterization of brain metastases and paired primary tumors reveals branched evolution and potential therapeutic targets European Journal of Cancer. 51: S586. DOI: 10.1016/S0959-8049(16)31622-7 |
0.334 |
|
2014 |
Shankar GM, Taylor-Weiner A, Lelic N, Jones RT, Kim JC, Francis JM, Abedalthagafi M, Borges LF, Coumans JV, Curry WT, Nahed BV, Shin JH, Paek SH, Park SH, Stewart C, ... ... Santagata S, et al. Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathologica Communications. 2: 167. PMID 25589003 DOI: 10.1186/S40478-014-0167-X |
0.379 |
|
2014 |
Abedalthagafi MS, Merrill PH, Bi WL, Jones RT, Listewnik ML, Ramkissoon SH, Thorner AR, Dunn IF, Beroukhim R, Alexander BM, Brastianos PK, Francis JM, Folkerth RD, Ligon KL, Van Hummelen P, ... ... Santagata S, et al. Angiomatous meningiomas have a distinct genetic profile with multiple chromosomal polysomies including polysomy of chromosome 5. Oncotarget. 5: 10596-606. PMID 25347344 DOI: 10.18632/Oncotarget.2517 |
0.306 |
|
2014 |
Cryan JB, Haidar S, Ramkissoon LA, Bi WL, Knoff DS, Schultz N, Abedalthagafi M, Brown L, Wen PY, Reardon DA, Dunn IF, Folkerth RD, Santagata S, Lindeman NI, Ligon AH, et al. Clinical multiplexed exome sequencing distinguishes adult oligodendroglial neoplasms from astrocytic and mixed lineage gliomas. Oncotarget. 5: 8083-92. PMID 25257301 DOI: 10.18632/Oncotarget.2342 |
0.385 |
|
2014 |
Scherz-Shouval R, Santagata S, Mendillo ML, Sholl LM, Ben-Aharon I, Beck AH, Dias-Santagata D, Koeva M, Stemmer SM, Whitesell L, Lindquist S. The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy. Cell. 158: 564-78. PMID 25083868 DOI: 10.1016/J.Cell.2014.05.045 |
0.352 |
|
2014 |
Santagata S, Eberlin LS, Norton I, Calligaris D, Feldman DR, Ide JL, Liu X, Wiley JS, Vestal ML, Ramkissoon SH, Orringer DA, Gill KK, Dunn IF, Dias-Santagata D, Ligon KL, et al. Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery. Proceedings of the National Academy of Sciences of the United States of America. 111: 11121-6. PMID 24982150 DOI: 10.1073/Pnas.1404724111 |
0.326 |
|
2014 |
Wen PY, Chang SM, Lamborn KR, Kuhn JG, Norden AD, Cloughesy TF, Robins HI, Lieberman FS, Gilbert MR, Mehta MP, Drappatz J, Groves MD, Santagata S, Ligon AH, Yung WK, et al. Phase I/II study of erlotinib and temsirolimus for patients with recurrent malignant gliomas: North American Brain Tumor Consortium trial 04-02. Neuro-Oncology. 16: 567-78. PMID 24470557 DOI: 10.1093/Neuonc/Not247 |
0.303 |
|
2014 |
Santagata S, Thakkar A, Ergonul A, Wang B, Woo T, Hu R, Harrell JC, McNamara G, Schwede M, Culhane AC, Kindelberger D, Rodig S, Richardson A, Schnitt SJ, Tamimi RM, et al. Taxonomy of breast cancer based on normal cell phenotype predicts outcome. The Journal of Clinical Investigation. 124: 859-70. PMID 24463450 DOI: 10.1172/Jci70941 |
0.321 |
|
2014 |
Brastianos PK, Taylor-Weiner A, Manley PE, Jones RT, Dias-Santagata D, Thorner AR, Lawrence MS, Rodriguez FJ, Bernardo LA, Schubert L, Sunkavalli A, Shillingford N, Calicchio ML, Lidov HG, Taha H, ... ... Santagata S, et al. Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas. Nature Genetics. 46: 161-5. PMID 24413733 DOI: 10.1038/Ng.2868 |
0.381 |
|
2014 |
Ramkissoon S, Bi WL, Haidar S, Cryan JB, Reardon DA, Lee EQ, Rinne ML, Norden AD, Nayak L, Russo AL, Arvold ND, Santagata S, Dunn IF, Folkerth RD, Lindeman NI, et al. Integrative whole-genome copy number analysis and mutation profiling of FFPE brain tumor specimens and potential in designing multi-arm clinical trials. Journal of Clinical Oncology. 32: 11098-11098. DOI: 10.1200/Jco.2014.32.15_Suppl.11098 |
0.34 |
|
2014 |
Brastianos PK, Carter SL, Santagata S, Taylor-Weiner A, Jones RT, Horowitz PM, Ligon KL, Seaone J, Martinez-Saez E, Tabernero J, Cahill DP, Paek S, Dunn IF, Johnson BE, Choueiri TK, et al. Abstract NG03: Genomic characterization of 101 brain metastases and paired primary tumors reveals patterns of clonal evolution and selection of driver mutations Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Ng03 |
0.382 |
|
2014 |
Brastianos P, Taylor-Weiner A, Manley P, Jones R, Dias-Santagata D, Thorner A, Rodriguez F, Bernardo L, Schubert L, Stewart C, Kieran M, Louis D, Getz G, Santagata S. GE-05 * EXOME SEQUENCING REVEALS BRAF MUTATIONS IN PAPILLARY CRANIOPHARYNGIOMAS Neuro-Oncology. 16: v97-v97. DOI: 10.1093/Neuonc/Nou256.5 |
0.38 |
|
2014 |
Brastianos P, Carter S, Santagata S, Taylor-Weiner A, Jones R, Van Allen E, Horowitz P, Ligon K, Cahill D, Dunn I, Van Hummelen P, Lin N, Curry W, Stemmer-Rachamimov A, Beroukhim R, et al. BM-07 * GENOMIC CHARACTERIZATION OF BRAIN METASTASES REVEALS BRANCHED EVOLUTION AND METASTASIS-SPECIFIC MUTATIONS Neuro-Oncology. 16: v33-v33. DOI: 10.1093/Neuonc/Nou240.7 |
0.368 |
|
2013 |
Calligaris D, Norton I, Feldman DR, Ide JL, Dunn IF, Eberlin LS, Cooks RG, Jolesz FA, Golby AJ, Santagata S, Agar NY. Mass spectrometry imaging as a tool for surgical decision-making. Journal of Mass Spectrometry : Jms. 48: 1178-87. PMID 24259206 DOI: 10.1002/Jms.3295 |
0.308 |
|
2013 |
Ji M, Orringer DA, Freudiger CW, Ramkissoon S, Liu X, Lau D, Golby AJ, Norton I, Hayashi M, Agar NY, Young GS, Spino C, Santagata S, Camelo-Piragua S, Ligon KL, et al. Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy. Science Translational Medicine. 5: 201ra119. PMID 24005159 DOI: 10.1126/Scitranslmed.3005954 |
0.321 |
|
2013 |
Ramkissoon LA, Horowitz PM, Craig JM, Ramkissoon SH, Rich BE, Schumacher SE, McKenna A, Lawrence MS, Bergthold G, Brastianos PK, Tabak B, Ducar MD, Van Hummelen P, MacConaill LE, Pouissant-Young T, ... ... Santagata S, et al. Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1. Proceedings of the National Academy of Sciences of the United States of America. 110: 8188-93. PMID 23633565 DOI: 10.1073/Pnas.1300252110 |
0.357 |
|
2013 |
Brastianos PK, Horowitz PM, Santagata S, Jones RT, McKenna A, Getz G, Ligon KL, Palescandolo E, Van Hummelen P, Ducar MD, Raza A, Sunkavalli A, Macconaill LE, Stemmer-Rachamimov AO, Louis DN, et al. Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. Nature Genetics. 45: 285-9. PMID 23334667 DOI: 10.1038/Ng.2526 |
0.393 |
|
2013 |
Eberlin LS, Norton I, Orringer D, Dunn IF, Liu X, Ide JL, Jarmusch AK, Ligon KL, Jolesz FA, Golby AJ, Santagata S, Agar NY, Cooks RG. Ambient mass spectrometry for the intraoperative molecular diagnosis of human brain tumors. Proceedings of the National Academy of Sciences of the United States of America. 110: 1611-6. PMID 23300285 DOI: 10.1073/Pnas.1215687110 |
0.343 |
|
2013 |
Alexander BM, Ramkissoon S, Wen PY, Reardon DA, Lee EQ, Rinne M, Norden AD, Nayak L, Ruland S, Doherty LM, LaFrankie DC, Brown LE, Arvold ND, Dunn IF, Santagata S, et al. Combined whole genome copy number genotyping and multiplex somatic mutation profiling of FFPE brain tumor specimens for clinical diagnosis and trial selection. Journal of Clinical Oncology. 31: 2030-2030. DOI: 10.1200/Jco.2013.31.15_Suppl.2030 |
0.38 |
|
2013 |
Scherz-Shouval R, Santagata S, Koeva M, Whitesell L, Lindquist S. Abstract A23: Cell autonomous and nonautonomous activities of heat shock factor 1 support tumor initiation, progression, and metastasis Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A23 |
0.343 |
|
2013 |
Brastianos P, Horowitz PM, Santagata S, Jones RT, McKenna A, Getz G, Ligon K, Hummelen PV, Ducar M, Raza A, Sunkavalli A, MacConaill L, Stemmer-Rachamimov A, Louis DN, Hahn WC, et al. Abstract 803: Genomic sequencing of meningiomas reveals oncogenic SMO and AKT1 mutations. Cancer Research. 73: 803-803. DOI: 10.1158/1538-7445.Am2013-803 |
0.405 |
|
2012 |
Dai C, Santagata S, Tang Z, Shi J, Cao J, Kwon H, Bronson RT, Whitesell L, Lindquist S. Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis. The Journal of Clinical Investigation. 122: 3742-54. PMID 22945628 DOI: 10.1172/Jci62727 |
0.324 |
|
2012 |
Craig JM, Vena N, Ramkissoon S, Idbaih A, Fouse SD, Ozek M, Sav A, Hill DA, Margraf LR, Eberhart CG, Kieran MW, Norden AD, Wen PY, Loda M, Santagata S, et al. DNA fragmentation simulation method (FSM) and fragment size matching improve aCGH performance of FFPE tissues. Plos One. 7: e38881. PMID 22719973 DOI: 10.1371/Journal.Pone.0038881 |
0.313 |
|
2012 |
Eberlin LS, Norton I, Dill AL, Golby AJ, Ligon KL, Santagata S, Cooks RG, Agar NY. Classifying human brain tumors by lipid imaging with mass spectrometry. Cancer Research. 72: 645-54. PMID 22139378 DOI: 10.1158/0008-5472.Can-11-2465 |
0.326 |
|
2012 |
Brastianos PK, Horowitz P, Santagata S, Jones RT, McKenna A, Ligon K, Palescandolo E, Van Hummelen P, Getz G, Hahn WC, Dunn IF, Beroukhim R. Genomic characterization of meningiomas. Journal of Clinical Oncology. 30: 2020-2020. DOI: 10.1200/Jco.2012.30.15_Suppl.2020 |
0.403 |
|
2011 |
Tian Y, Rich BE, Vena N, Craig JM, Macconaill LE, Rajaram V, Goldman S, Taha H, Mahmoud M, Ozek M, Sav A, Longtine JA, Lindeman NI, Garraway LA, Ligon AH, ... ... Santagata S, et al. Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas. The Journal of Molecular Diagnostics : Jmd. 13: 669-77. PMID 21884820 DOI: 10.1016/J.Jmoldx.2011.07.002 |
0.372 |
|
2011 |
Dias-Santagata D, Lam Q, Vernovsky K, Vena N, Lennerz JK, Borger DR, Batchelor TT, Ligon KL, Iafrate AJ, Ligon AH, Louis DN, Santagata S. BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications. Plos One. 6: e17948. PMID 21479234 DOI: 10.1371/Journal.Pone.0017948 |
0.381 |
|
2011 |
Milbury CA, Chen CC, Mamon H, Liu P, Santagata S, Makrigiorgos GM. Multiplex amplification coupled with COLD-PCR and high resolution melting enables identification of low-abundance mutations in cancer samples with low DNA content. The Journal of Molecular Diagnostics : Jmd. 13: 220-32. PMID 21354058 DOI: 10.1016/J.Jmoldx.2010.10.008 |
0.329 |
|
2011 |
Cho YJ, Tsherniak A, Tamayo P, Santagata S, Ligon A, Greulich H, Berhoukim R, Amani V, Goumnerova L, Eberhart CG, Lau CC, Olson JM, Gilbertson RJ, Gajjar A, Delattre O, et al. Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 1424-30. PMID 21098324 DOI: 10.1200/Jco.2010.28.5148 |
0.324 |
|
2011 |
Mendillo M, Santagata S, Koeva M, Fraenkel E, Ince T, Whitesell L, Lindquist S. P3-01-09: Oncogenic Activation of HSF1 Enables the Malignant Progression of Breast Carcinoma. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P3-01-09 |
0.34 |
|
2010 |
MacConaill LE, Campbell CD, Kehoe SM, Bass AJ, Hatton C, Niu L, Davis M, Yao K, Hanna M, Mondal C, Luongo L, Emery CM, Baker AC, Philips J, Goff DJ, ... ... Santagata S, et al. Correction: Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples Plos One. 5. DOI: 10.1371/Annotation/3A0C8Fee-57Ef-43Ed-B6C2-55B503E6Db5E |
0.323 |
|
2009 |
Santagata S, Maire CL, Idbaih A, Geffers L, Correll M, Holton K, Quackenbush J, Ligon KL. CRX is a diagnostic marker of retinal and pineal lineage tumors. Plos One. 4: e7932. PMID 19936203 DOI: 10.1371/Journal.Pone.0007932 |
0.351 |
|
2009 |
MacConaill LE, Campbell CD, Kehoe SM, Bass AJ, Hatton C, Niu L, Davis M, Yao K, Hanna M, Mondal C, Luongo L, Emery CM, Baker AC, Philips J, Goff DJ, ... ... Santagata S, et al. Profiling critical cancer gene mutations in clinical tumor samples. Plos One. 4: e7887. PMID 19924296 DOI: 10.1371/Journal.Pone.0007887 |
0.365 |
|
2005 |
Dahia PL, Ross KN, Wright ME, Hayashida CY, Santagata S, Barontini M, Kung AL, Sanso G, Powers JF, Tischler AS, Hodin R, Heitritter S, Moore F, Dluhy R, Sosa JA, et al. A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas. Plos Genetics. 1: 72-80. PMID 16103922 DOI: 10.1371/Journal.Pgen.0010008 |
0.383 |
|
2001 |
Notarangelo LD, Santagata S, Villa A. Recombinase activating gene enzymes of lymphocytes. Current Opinion in Hematology. 8: 41-6. PMID 11138625 DOI: 10.1097/00062752-200101000-00008 |
0.328 |
|
2001 |
Villa A, Sobacchi C, Notarangelo LD, Bozzi F, Abinun M, Abrahamsen TG, Arkwright PD, Baniyash M, Brooks EG, Conley ME, Cortes P, Duse M, Fasth A, Filipovich AM, Infante AJ, ... ... Santagata S, et al. V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations. Blood. 97: 81-8. PMID 11133745 DOI: 10.1182/Blood.V97.1.81 |
0.355 |
|
2000 |
Santagata S, Villa A, Sobacchi C, Cortes P, Vezzoni P. The genetic and biochemical basis of Omenn syndrome. Immunological Reviews. 178: 64-74. PMID 11213808 DOI: 10.1034/J.1600-065X.2000.17818.X |
0.355 |
|
2000 |
Santagata S, Gomez CA, Sobacchi C, Bozzi F, Abinun M, Pasic S, Cortes P, Vezzoni P, Villa A. N-terminal RAG1 frameshift mutations in Omenn's syndrome: internal methionine usage leads to partial V(D)J recombination activity and reveals a fundamental role in vivo for the N-terminal domains. Proceedings of the National Academy of Sciences of the United States of America. 97: 14572-7. PMID 11121059 DOI: 10.1073/Pnas.97.26.14572 |
0.347 |
|
2000 |
Gomez CA, Ptaszek LM, Villa A, Bozzi F, Sobacchi C, Brooks EG, Notarangelo LD, Spanopoulou E, Pan ZQ, Vezzoni P, Cortes P, Santagata S. Mutations in conserved regions of the predicted RAG2 kelch repeats block initiation of V(D)J recombination and result in primary immunodeficiencies. Molecular and Cellular Biology. 20: 5653-64. PMID 10891502 DOI: 10.1128/Mcb.20.15.5653-5664.2000 |
0.717 |
|
2000 |
Aidinis V, Dias DC, Gomez CA, Bhattacharyya D, Spanopoulou E, Santagata S. Definition of minimal domains of interaction within the recombination-activating genes 1 and 2 recombinase complex. Journal of Immunology (Baltimore, Md. : 1950). 164: 5826-32. PMID 10820261 DOI: 10.4049/Jimmunol.164.11.5826 |
0.703 |
|
1999 |
Aidinis V, Bonaldi T, Beltrame M, Santagata S, Bianchi ME, Spanopoulou E. The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2. Molecular and Cellular Biology. 19: 6532-42. PMID 10490593 DOI: 10.1128/Mcb.19.10.6532 |
0.707 |
|
1999 |
Santagata S, Bhattacharyya D, Wang FH, Singha N, Hodtsev A, Spanopoulou E. Molecular cloning and characterization of a mouse homolog of bacterial ClpX, a novel mammalian class II member of the Hsp100/Clp chaperone family. The Journal of Biological Chemistry. 274: 16311-9. PMID 10347188 DOI: 10.1074/Jbc.274.23.16311 |
0.7 |
|
1999 |
Villa A, Santagata S, Bozzi F, Imberti L, Notarangelo LD. Omenn syndrome: a disorder of Rag1 and Rag2 genes. Journal of Clinical Immunology. 19: 87-97. PMID 10226883 DOI: 10.1023/A:1020550432126 |
0.332 |
|
1998 |
Santagata S, Aidinis V, Spanopoulou E. The effect of Me2+ cofactors at the initial stages of V(D)J recombination. The Journal of Biological Chemistry. 273: 16325-31. PMID 9632694 DOI: 10.1074/Jbc.273.26.16325 |
0.704 |
|
1998 |
Villa A, Santagata S, Bozzi F, Giliani S, Frattini A, Imberti L, Gatta LB, Ochs HD, Schwarz K, Notarangelo LD, Vezzoni P, Spanopoulou E. Partial V(D)J recombination activity leads to Omenn syndrome. Cell. 93: 885-96. PMID 9630231 DOI: 10.1016/S0092-8674(00)81448-8 |
0.719 |
|
1996 |
Spanopoulou E, Zaitseva F, Wang FH, Santagata S, Baltimore D, Panayotou G. The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination. Cell. 87: 263-76. PMID 8861910 DOI: 10.1016/S0092-8674(00)81344-6 |
0.707 |
|
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