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Dennis E. Hruby

Affiliations: 
Oregon State University, Corvallis, OR 
Area:
Microbiology Biology
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"Dennis Hruby"
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Dawn M. Myscofski grad student 2000 Oregon State
Chelsea M. Byrd grad student 2005 Oregon State
Travis K. Warren grad student 2006 Oregon State

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Publications

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Grosenbach DW, Hruby DE. (2019) Preliminary Screening and In Vitro Confirmation of Orthopoxvirus Antivirals. Methods in Molecular Biology (Clifton, N.J.). 2023: 143-155
Berhanu A, Prigge JT, Silvera PM, et al. (2015) Treatment with the smallpox antiviral tecovirimat (ST-246) alone or in combination with ACAM2000 vaccination is effective as a postsymptomatic therapy for monkeypox virus infection. Antimicrobial Agents and Chemotherapy. 59: 4296-300
Duraffour S, Lorenzo MM, Zöller G, et al. (2015) ST-246 is a key antiviral to inhibit the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping. The Journal of Antimicrobial Chemotherapy. 70: 1367-80
Byrd CM, Grosenbach DW, Hruby DE. (2013) Antiviral options for biodefense. Current Opinion in Virology. 3: 537-41
Byrd CM, Grosenbach DW, Berhanu A, et al. (2013) Novel benzoxazole inhibitor of dengue virus replication that targets the NS3 helicase. Antimicrobial Agents and Chemotherapy. 57: 1902-12
Santos-Fernandes É, Beltrame CO, Byrd CM, et al. (2013) Increased susceptibility of Cantagalo virus to the antiviral effect of ST-246®. Antiviral Research. 97: 301-11
Leeds JM, Fenneteau F, Gosselin NH, et al. (2013) Pharmacokinetic and pharmacodynamic modeling to determine the dose of ST-246 to protect against smallpox in humans. Antimicrobial Agents and Chemotherapy. 57: 1136-43
Byrd CM, Dai D, Grosenbach DW, et al. (2013) A novel inhibitor of dengue virus replication that targets the capsid protein. Antimicrobial Agents and Chemotherapy. 57: 15-25
Byrd CM, Bolken TC, Hruby DE. (2013) Vaccinia Virus Cysteine Proteinase Handbook of Proteolytic Enzymes. 2: 2390-2392
Byrd CM, Bolken TC, Hruby DE. (2013) Vaccinia Virus Metalloproteinase Handbook of Proteolytic Enzymes. 1: 1462-1464
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