Robert L. Eoff, Ph.D.
Affiliations: | 2005 | University of Arkansas for Medical Sciences, United States |
Area:
Biochemistry, Molecular BiologyGoogle:
"Robert Eoff"Parents
Sign in to add mentor| Kevin Raney | grad student | 2005 | UAMS | |
| (Investigation into the mechanism of DNA unwinding by the bacteriophage T4 Dda helicase: Characterization of the transition from a monomeric to a multimeric molecular motor.) | ||||
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Publications
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| Ketkar A, Sewilam RS, McCrury MJ, et al. (2023) Conservation of the insert-2 motif confers Rev1 from different species with an ability to disrupt G-quadruplexes and stimulate translesion DNA synthesis. Rsc Chemical Biology. 4: 466-485 |
| Urbaniak A, Reed MR, Heflin B, et al. (2022) Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 153: 113440 |
| Christov PP, Richie-Jannetta R, Kingsley PJ, et al. (2021) Site-Specific Synthesis of Oligonucleotides Containing 6-Oxo-MdG, the Genomic Metabolite of MdG, and Liquid Chromatography-Tandem Mass Spectrometry Analysis of Its In Vitro Bypass by Human Polymerase ι. Chemical Research in Toxicology |
| Reed MR, Maddukuri L, Ketkar A, et al. (2021) Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells. Nar Cancer. 3: zcab014 |
| Ketkar A, Maddukuri L, Penthala NR, et al. (2019) Inhibition of human DNA polymerases eta and kappa by indole-derived molecules occurs through distinct mechanisms. Acs Chemical Biology |
| West KL, Kelliher JL, Xu Z, et al. (2019) LC8/DYNLL1 is a 53BP1 effector and regulates checkpoint activation. Nucleic Acids Research |
| Zafar MK, Maddukuri L, Ketkar A, et al. (2018) A small-molecule inhibitor of human DNA polymerase eta potentiates the effects of cisplatin in tumor cells. Biochemistry |
| Zafar MK, Eoff RL. (2017) Translesion DNA synthesis in cancer: molecular mechanisms and therapeutic opportunities. Chemical Research in Toxicology |
| Eoff RL, Raney KD. (2017) A catch and release program for single-stranded DNA. The Journal of Biological Chemistry. 292: 13085-13086 |
| Ketkar A, Voehler M, Mukiza T, et al. (2017) Residues in the RecQ C-terminal Domain of the Human Werner Syndrome Helicase are Involved in Unwinding G-quadruplex DNA. The Journal of Biological Chemistry |