R Scott McIvor

Affiliations: 
Microbiology, Immunology and Cancer Biology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Molecular Biology, Virology Biology, Microbiology Biology
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"R McIvor"

Children

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Seth D. Hartung grad student 2003 UMN
Colin L. Sweeney grad student 2003 UMN
Andrew C. Wilber grad student 2006 UMN
Paul R. Score grad student 2008 UMN
Megan M. Multhaup grad student 2010 UMN

Collaborators

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William H. Frey II collaborator (Neurotree)
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Publications

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Webber BR, Johnson MJ, Skeate JG, et al. (2023) Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair. Nature Biomedical Engineering
Cowan MJ, Yu J, Facchino J, et al. (2022) Lentiviral Gene Therapy for Artemis-Deficient SCID. The New England Journal of Medicine. 387: 2344-2355
Sipe CJ, Kluesner MG, Bingea SP, et al. (2022) Correction of Fanconi Anemia Mutations Using Digital Genome Engineering. International Journal of Molecular Sciences. 23
Belur LR, Podetz-Pedersen KM, Tran TA, et al. (2020) Intravenous delivery for treatment of mucopolysaccharidosis type I: A comparison of AAV serotypes 9 and rh10. Molecular Genetics and Metabolism Reports. 24: 100604
McIvor RS, de Laat R, Mei X, et al. (2020) Iduronidase-transposed human B lymphocytes correct enzyme deficiency and glycosaminoglycan storage disease in immunodeficient mucopolysaccharidosis type I mice Molecular Genetics and Metabolism. 129: S108
Belur L, McKenzie J, Podetz-Pedersen K, et al. (2020) Systemic high-level IDUA enzyme activity with correction of neurologic deficit in mucopolysaccharidosis type I mice by lentiviral transduction of hematopoietic stem cells Molecular Genetics and Metabolism. 129: S30-S31
Cowan MJ, Yu J, Facchino J, et al. (2020) Early Outcome of a Phase I/II Clinical Trial (NCT03538899) of Gene-Corrected Autologous CD34+ Hematopoietic Cells and Low-Exposure Busulfan in Newly Diagnosed Patients with Artemis-Deficient Severe Combined Immunodeficiency (ART-SCID) Biology of Blood and Marrow Transplantation. 26: S88-S89
Ou L, DeKelver RC, Rohde M, et al. (2018) ZFN-Mediated In Vivo Genome Editing Corrects Murine Hurler Syndrome. Molecular Therapy : the Journal of the American Society of Gene Therapy
Laoharawee K, DeKelver RC, Podetz-Pedersen KM, et al. (2018) Dose-Dependent Prevention of Metabolic and Neurologic Disease in Murine MPS II by ZFN-Mediated In Vivo Genome Editing. Molecular Therapy : the Journal of the American Society of Gene Therapy
Aronovich EL, Hyland KA, Hall BC, et al. (2017) Prolonged expression of secreted enzymes in dogs after liver-directed delivery of Sleeping Beauty transposons: implications for non-viral gene therapy of systemic disease. Human Gene Therapy
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