Randall J. Roper, Ph.D.

Affiliations: 
2001 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Genetics, Immunology
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"Randall Roper"

Parents

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Lawrence B. Schook grad student 2001 UIUC
 (Genetic control of experimentally induced reproductive autoimmune phenotypes.)
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Publications

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Lamantia J, Sloan K, Wallace JM, et al. (2024) Compromised femoral and lumbovertebral bone in the Dp(16)1Yey down syndrome mouse model. Bone. 117046
Hawley LE, Stringer M, Deal AJ, et al. (2023) Sex-specific developmental alterations in DYRK1A expression in the brain of a Down syndrome mouse model. Neurobiology of Disease. 190: 106359
Sloan K, Thomas J, Blackwell M, et al. (2023) Genetic dissection of triplicated Hsa21 orthologs produces differential skeletal phenotypes in Down syndrome mouse models. Disease Models & Mechanisms
Fulton SL, Wenderski W, Lepack AE, et al. (2022) Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome. Nature Communications. 13: 6384
Hawley LE, Prochaska F, Stringer M, et al. (2022) Sexually dimorphic DYRK1A overexpression on postnatal day 15 in the Ts65Dn mouse model of Down syndrome: Effects of pharmacological targeting on behavioral phenotypes. Pharmacology, Biochemistry, and Behavior. 217: 173404
Thomas JR, Sloan K, Cave K, et al. (2021) Skeletal Deficits in Male and Female down Syndrome Model Mice Arise Independent of Normalized Dyrk1a Expression in Osteoblasts. Genes. 12
Roper RJ, Goodlett CR, Martínez de Lagrán M, et al. (2020) Behavioral Phenotyping for Down Syndrome in Mice. Current Protocols in Mouse Biology. 10: e79
Goodlett CR, Stringer M, LaCombe J, et al. (2020) Evaluation of the therapeutic potential of Epigallocatechin-3-gallate (EGCG) via oral gavage in young adult Down syndrome mice. Scientific Reports. 10: 10426
Thomas JR, LaCombe J, Long R, et al. (2020) Interaction of sexual dimorphism and gene dosage imbalance in skeletal deficits associated with Down syndrome. Bone. 115367
Roper RJ, Hawley L, Goodlett CR. (2020) Influence of allelic differences in Down syndrome. Progress in Brain Research. 251: 29-54
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