Sylvain Meloche

Université de Montréal, Montréal, Canada 
Microbiology Biology, Pharmacy
"Sylvain Meloche"
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Soulez M, Saba-El-Leil MK, Turgeon B, et al. (2019) Reevaluation of the Role of ERK3 in Perinatal Survival and Post-Natal Growth Using New Genetically-Engineered Mouse Models. Molecular and Cellular Biology
Pyakurel A, Balmer D, Saba-El-Leil MK, et al. (2017) Loss of ERK1/2 in the retinal pigment epithelium leads to RPE65 decrease and retinal degeneration. Molecular and Cellular Biology
Mathien S, Déléris P, Soulez M, et al. (2017) The Deubiquitinating Enzyme USP20 Regulates ERK3 Stability and Biological Activity. Molecular and Cellular Biology
Duhamel S, Girondel C, Dorn JF, et al. (2016) Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway. Cell Cycle (Georgetown, Tex.). 0
Grote D, Moison C, Duhamel S, et al. (2015) E4F1 is a master regulator of CHK1-mediated functions. Cell Reports. 11: 210-9
Bordeleau ME, Aucagne R, Chagraoui J, et al. (2014) UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity. Blood. 124: 2362-9
Redwan IN, Dyrager C, Solano C, et al. (2014) Towards the development of chromone-based MEK1/2 modulators. European Journal of Medicinal Chemistry. 85: 127-38
Courcelles M, Frémin C, Voisin L, et al. (2013) Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions. Molecular Systems Biology. 9: 669
van Zuylen WJ, Doyon P, Clément JF, et al. (2012) Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity. Plos Pathogens. 8: e1002747
Duhamel S, Hébert J, Gaboury L, et al. (2012) Sef downregulation by Ras causes MEK1/2 to become aberrantly nuclear localized leading to polyploidy and neoplastic transformation. Cancer Research. 72: 626-35
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