Nathan E. Goldfarb, Ph.D.
Affiliations: | 2003 | University of Florida, Gainesville, Gainesville, FL, United States |
Area:
BiochemistryGoogle:
"Nathan Goldfarb"Parents
Sign in to add mentorBen M. Dunn | grad student | 2003 | UF Gainesville | |
(Inspection of ion switch residues that mediate the pH -dependent conformational change of "short" recombinant human pseudocathepsin D.) |
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Publications
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Wlodawer A, Li M, Gustchina A, et al. (2018) Correction to "Inhibitor Complexes of the Pseudomonas Serine-Carboxyl Proteinase". Biochemistry |
Naffin-Olivos JL, Daab A, White A, et al. (2017) Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c). Biochemistry |
Quiliano M, Mendoza A, Fong KY, et al. (2016) Exploring the scope of new arylamino alcohol derivatives: Synthesis, antimalarial evaluation, toxicological studies, and target exploration. International Journal For Parasitology. Drugs and Drug Resistance. 6: 184-198 |
Liu Z, Huang X, Hu L, et al. (2016) Effects of Hinge Region Natural Polymorphisms on Human Immunodeficiency Virus-1 Protease Structure, Dynamics and Drug-Pressure Evolution. The Journal of Biological Chemistry |
Liu Z, Huang X, Hu L, et al. (2016) Implication of Natural Polymorphism in Hinge Region of HIV-1 Protease on Protein Conformations, Local Structures and Backbone Dynamics Biophysical Journal. 110: 207a |
Singh AK, Rathore S, Tang Y, et al. (2015) Hydroxyethylamine Based Phthalimides as New Class of Plasmepsin Hits: Design, Synthesis and Antimalarial Evaluation. Plos One. 10: e0139347 |
Goldfarb NE, Ohanessian M, Biswas S, et al. (2015) Defective hydrophobic sliding mechanism and active site expansion in HIV-1 protease drug resistant variant Gly48Thr/Leu89Met: mechanisms for the loss of saquinavir binding potency. Biochemistry. 54: 422-33 |
Mahindra A, Gangwal RP, Bansal S, et al. (2015) Antiplasmodial activity of short peptide-based compounds Rsc Advances. 5: 22674-22684 |
Naffin-Olivos JL, Georgieva M, Goldfarb N, et al. (2014) Mycobacterium tuberculosis Hip1 modulates macrophage responses through proteolysis of GroEL2. Plos Pathogens. 10: e1004132 |
Jones SA, Neilsen PM, Siew L, et al. (2013) A template-based approach to inhibitors of calpain 2, 20S proteasome, and HIV-1 protease. Chemmedchem. 8: 1918-21 |