Nathan E. Goldfarb, Ph.D.

Affiliations: 
2003 University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Biochemistry
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"Nathan Goldfarb"

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Ben M. Dunn grad student 2003 UF Gainesville
 (Inspection of ion switch residues that mediate the pH -dependent conformational change of "short" recombinant human pseudocathepsin D.)
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Publications

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Wlodawer A, Li M, Gustchina A, et al. (2018) Correction to "Inhibitor Complexes of the Pseudomonas Serine-Carboxyl Proteinase". Biochemistry
Naffin-Olivos JL, Daab A, White A, et al. (2017) Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c). Biochemistry
Quiliano M, Mendoza A, Fong KY, et al. (2016) Exploring the scope of new arylamino alcohol derivatives: Synthesis, antimalarial evaluation, toxicological studies, and target exploration. International Journal For Parasitology. Drugs and Drug Resistance. 6: 184-198
Liu Z, Huang X, Hu L, et al. (2016) Effects of Hinge Region Natural Polymorphisms on Human Immunodeficiency Virus-1 Protease Structure, Dynamics and Drug-Pressure Evolution. The Journal of Biological Chemistry
Liu Z, Huang X, Hu L, et al. (2016) Implication of Natural Polymorphism in Hinge Region of HIV-1 Protease on Protein Conformations, Local Structures and Backbone Dynamics Biophysical Journal. 110: 207a
Singh AK, Rathore S, Tang Y, et al. (2015) Hydroxyethylamine Based Phthalimides as New Class of Plasmepsin Hits: Design, Synthesis and Antimalarial Evaluation. Plos One. 10: e0139347
Goldfarb NE, Ohanessian M, Biswas S, et al. (2015) Defective hydrophobic sliding mechanism and active site expansion in HIV-1 protease drug resistant variant Gly48Thr/Leu89Met: mechanisms for the loss of saquinavir binding potency. Biochemistry. 54: 422-33
Mahindra A, Gangwal RP, Bansal S, et al. (2015) Antiplasmodial activity of short peptide-based compounds Rsc Advances. 5: 22674-22684
Naffin-Olivos JL, Georgieva M, Goldfarb N, et al. (2014) Mycobacterium tuberculosis Hip1 modulates macrophage responses through proteolysis of GroEL2. Plos Pathogens. 10: e1004132
Jones SA, Neilsen PM, Siew L, et al. (2013) A template-based approach to inhibitors of calpain 2, 20S proteasome, and HIV-1 protease. Chemmedchem. 8: 1918-21
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