Year |
Citation |
Score |
2023 |
Burkhart JG, Wu G, Song X, Raimondi F, McWeeney S, Wong MH, Deng Y. Biology-inspired graph neural network encodes reactome and reveals biochemical reactions of disease. Patterns (New York, N.Y.). 4: 100758. PMID 37521042 DOI: 10.1016/j.patter.2023.100758 |
0.733 |
|
2020 |
Noll KE, Whitmore AC, West A, McCarthy MK, Morrison CR, Plante KS, Hampton BK, Kollmus H, Pilzner C, Leist SR, Gralinski LE, Menachery VD, Schäfer A, Miller D, Shaw G, ... ... McWeeney S, et al. Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross. Cell Reports. 31: 107587. PMID 32348764 DOI: 10.1016/J.Celrep.2020.107587 |
0.305 |
|
2020 |
Joshi SK, Qian K, Bisson WH, Watanabe-Smith K, Huang A, Bottomly D, Traer E, Tyner JW, McWeeney SK, Davare M, Druker BJ, Tognon CE. Discovery and Characterization of Targetable NTRK Point Mutations in Hematologic Neoplasms. Blood. PMID 32315394 DOI: 10.1182/Blood.2019003691 |
0.32 |
|
2020 |
Modak RV, Damnernsawad A, Laderas T, Wu G, Tyner JW, Rodland KD, McWeeney SK, Agarwal A. Abstract 5942: An integrated approach reveals novel extrinsic pathways and cytokine signatures associated with drug response in acute myeloid leukemia Immunology. 80: 5942-5942. DOI: 10.1158/1538-7445.Am2020-5942 |
0.34 |
|
2019 |
Braun TP, Okhovat M, Coblentz C, Carratt SA, Foley A, Schonrock Z, Smith BM, Nevonen K, Davis B, Garcia B, LaTocha D, Weeder BR, Grzadkowski MR, Estabrook JC, Manning HG, ... ... McWeeney S, et al. Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia. Nature Communications. 10: 5455. PMID 31784538 DOI: 10.1038/S41467-019-13364-2 |
0.308 |
|
2019 |
Tyner JW, Bottomly D, Wilmot B, McWeeney S. What do functional genomics tell us about pathogenesis of AML? Best Practice & Research. Clinical Haematology. 32: 101101. PMID 31779979 DOI: 10.1016/J.Beha.2019.101101 |
0.338 |
|
2019 |
Moshofsky KB, Cho HJ, Wu G, Romine KA, Newman MT, Kosaka Y, McWeeney SK, Lind EF. Acute myeloid leukemia-induced T-cell suppression can be reversed by inhibition of the MAPK pathway. Blood Advances. 3: 3038-3051. PMID 31648326 DOI: 10.1182/Bloodadvances.2019000574 |
0.326 |
|
2019 |
Luo X, Feurstein S, Mohan S, Porter CC, Jackson SA, Keel S, Chicka M, Brown AL, Kesserwan C, Agarwal A, Luo M, Li Z, Ross JE, Baliakas P, Pineda-Alvarez D, ... ... McWeeney SK, et al. ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants. Blood Advances. 3: 2962-2979. PMID 31648317 DOI: 10.1182/Bloodadvances.2019000644 |
0.347 |
|
2019 |
Choonoo G, Blucher AS, Higgins S, Boardman M, Jeng S, Zheng C, Jacobs J, Anderson A, Chamberlin S, Evans N, Vigoda M, Cordier B, Tyner JW, Kulesz-Martin M, McWeeney SK, et al. Illuminating biological pathways for drug targeting in head and neck squamous cell carcinoma. Plos One. 14: e0223639. PMID 31596908 DOI: 10.1371/Journal.Pone.0223639 |
0.312 |
|
2019 |
Blucher AS, McWeeney SK, Stein L, Wu G. Visualization of drug target interactions in the contexts of pathways and networks with ReactomeFIViz. F1000research. 8: 908. PMID 31372215 DOI: 10.12688/F1000Research.19592.1 |
0.315 |
|
2019 |
Zhang H, Wilmot B, Bottomly D, Dao KT, Stevens E, Eide CA, Khanna V, Rofelty A, Savage S, Reister-Schultz A, Long N, White L, Carlos A, Henson RA, Lin C, ... ... McWeeney SK, et al. Genomic landscape of Neutrophilic Leukemias of Ambiguous Diagnosis. Blood. PMID 31366621 DOI: 10.1182/Blood.2019000611 |
0.316 |
|
2019 |
Nechiporuk T, Kurtz SE, Nikolova O, Liu T, Jones CL, D'Alessandro A, Culp-Hill R, d'Almeida A, Joshi SK, Rosenberg M, Tognon CE, Danilov AV, Druker BJ, Chang BH, McWeeney SK, et al. The TP53 Apoptotic Network is a Primary Mediator of Resistance to BCL2 inhibition in AML Cells. Cancer Discovery. PMID 31048320 DOI: 10.1158/2159-8290.Cd-19-0125 |
0.324 |
|
2019 |
Swanson EA, Nelson JW, Jeng S, Erspamer KJ, Yang CL, McWeeney S, Ellison DH. The salt-sensitive transcriptome of isolated kidney distal tubule cells. Physiological Genomics. PMID 30875275 DOI: 10.1152/Physiolgenomics.00119.2018 |
0.313 |
|
2019 |
Zhang H, Savage S, Schultz AR, Bottomly D, White L, Segerdell E, Wilmot B, McWeeney SK, Eide CA, Nechiporuk T, Carlos A, Henson R, Lin C, Searles R, Ho H, et al. Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms. Nature Communications. 10: 244. PMID 30651561 DOI: 10.1038/S41467-018-08263-X |
0.328 |
|
2019 |
Drusbosky LM, Vidva R, Gera S, Lakshminarayana AV, Shyamasundar VP, Agrawal AK, Talawdekar A, Abbasi T, Vali S, Tognon CE, Kurtz SE, Tyner JW, McWeeney SK, Druker BJ, Cogle CR. Predicting response to BET inhibitors using computational modeling: A BEAT AML project study. Leukemia Research. PMID 30642575 DOI: 10.1016/J.Leukres.2018.11.010 |
0.341 |
|
2019 |
Bottomly D, Long N, Yang F, Lee T, Borate U, Wilmot B, DuVall AS, Monteblanco A, Thiel-Klare K, Dewson G, Press RD, Tognon CE, Druker BJ, Tyner JW, McWeeney SK, et al. Framework to Identify and Prioritize Candidate Inherited Myeloid Malignancy Germline Variants Leveraging the BEAT AML Cohort Blood. 134: 1407-1407. DOI: 10.1182/Blood-2019-132224 |
0.318 |
|
2019 |
Nechiporuk T, Damnernsawad A, Bottomly D, Morrow Q, Choi S, Beer S, Kurtz SE, McWeeney SK, Tyner JW. Genome-Wide CRISPR Screening in Acute Myeloid Leukemia Cells Identifies Genes in the PI3K/AKT/mTOR and MEK/ERK Pathways That Define Sensitivity to Trametinib Blood. 134: 1395-1395. DOI: 10.1182/Blood-2019-129117 |
0.333 |
|
2019 |
Damnernsawad A, Nechiporuk T, Bottomly D, Kurtz SE, Eide CA, McWeeney SK, Tyner JW. Genome-Wide CRISPR Screening Identifies MAPK and Mtorc Pathways As Regulators of Sorafenib Resistance in Acute Myeloid Leukemia Blood. 134: 2557-2557. DOI: 10.1182/Blood-2019-128877 |
0.334 |
|
2019 |
Joshi SK, Bisson W, Qian K, Huang A, Watanabe-Smith K, Tyner JW, Davare MA, McWeeney SK, Tognon CE, Druker BJ. Discovery & Characterization of Therapeutically Targetable Ntrk Point Mutations in Leukemia Blood. 134: 1256-1256. DOI: 10.1182/Blood-2019-125908 |
0.316 |
|
2019 |
Damnernsawad A, Nechiporuk T, Kurtz SE, Horton WR, Nikolova O, McWeeney SK, Tyner JW. Abstract 4763: Genome-wide CRISPR screening identifies TSC1 as a regulator of sorafenib resistance in acute myeloid leukemia Cancer Research. 79: 4763-4763. DOI: 10.1158/1538-7445.Sabcs18-4763 |
0.383 |
|
2019 |
Joshi SK, Christy S, Ribeiro RS, McWeeney S, Tyner JW, Tognon CE, Druker BJ, Traer E. Abstract 926: Extrinsic and intrinsic activation of RAS/MAPK signaling enables resistance to FLT3 inhibitor, gilteritinib, in acute myeloid leukemia Cancer Research. 79: 926-926. DOI: 10.1158/1538-7445.Am2019-926 |
0.313 |
|
2018 |
Edwards DK, Watanabe-Smith K, Rofelty A, Damnernsawad A, Laderas T, Lamble A, Lind EF, Kaempf A, Mori M, Rosenberg M, d'Almeida A, Long N, Agarwal A, Sweeney DT, Loriaux M, ... McWeeney SK, et al. CSF1R inhibitors exhibit anti-tumor activity in acute myeloid leukemia by blocking paracrine signals from support cells. Blood. PMID 30425048 DOI: 10.1182/Blood-2018-03-838946 |
0.348 |
|
2018 |
Tyner JW, Tognon CE, Bottomly D, Wilmot B, Kurtz SE, Savage SL, Long N, Schultz AR, Traer E, Abel M, Agarwal A, Blucher A, Borate U, Bryant J, Burke R, ... ... McWeeney SK, et al. Functional genomic landscape of acute myeloid leukaemia. Nature. PMID 30333627 DOI: 10.1038/S41586-018-0623-Z |
0.348 |
|
2018 |
Colville AM, Iancu OD, Lockwood DR, Darakjian P, McWeeney SK, Searles R, Zheng C, Hitzemann R. Regional Differences and Similarities in the Brain Transcriptome for Mice Selected for Ethanol Preference From HS-CC Founders. Frontiers in Genetics. 9: 300. PMID 30210525 DOI: 10.3389/Fgene.2018.00300 |
0.334 |
|
2018 |
Jenkins C, Luty SB, Maxson JE, Eide CA, Abel ML, Togiai C, Nemecek ER, Bottomly D, McWeeney SK, Wilmot B, Loriaux M, Chang BH, Tyner JW. Synthetic lethality of TNK2 inhibition in PTPN11-mutant leukemia. Science Signaling. 11. PMID 30018082 DOI: 10.1126/Scisignal.Aao5617 |
0.316 |
|
2018 |
Sanati N, Iancu OD, Wu G, Jacobs JE, McWeeney SK. Network-Based Predictors of Progression in Head and Neck Squamous Cell Carcinoma. Frontiers in Genetics. 9: 183. PMID 29910823 DOI: 10.3389/Fgene.2018.00183 |
0.341 |
|
2018 |
Goodrum F, McWeeney S. A Single-Cell Approach to the Elusive Latent Human Cytomegalovirus Transcriptome. Mbio. 9. PMID 29895640 DOI: 10.1128/Mbio.01001-18 |
0.351 |
|
2018 |
Edwards V DK, Sweeney DT, Ho H, Eide CA, Rofelty A, Agarwal A, Liu SQ, Danilov AV, Lee P, Chantry D, McWeeney SK, Druker BJ, Tyner JW, Spurgeon SE, Loriaux MM. Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples. Oncotarget. 9: 24576-24589. PMID 29872489 DOI: 10.18632/Oncotarget.25191 |
0.331 |
|
2018 |
Ouyang X, Barling A, Lesch A, Tyner JW, Choonoo G, Zheng C, Jeng S, West TM, Clayburgh D, Courtneidge SA, McWeeney SK, Kulesz-Martin M. Induction of anaplastic lymphoma kinase (ALK) as a novel mechanism of EGFR inhibitor resistance in head and neck squamous cell carcinoma patient-derived models. Cancer Biology & Therapy. 1-37. PMID 29856687 DOI: 10.1080/15384047.2018.1451285 |
0.304 |
|
2018 |
Godley L, Luo X, Ross J, Jackson S, Agarwal A, Baliakas P, Bertuch AA, Brown AL, Chicka MC, DiNardo CD, Fleming MD, Keel S, Kesserwan C, Li Z, Luo M, ... ... McWeeney SK, et al. Myeloid Malignancy Variant Curation Expert Panel: An ASH-Sponsored Clingen Expert Panel to Optimize and Validate Acmg/AMP Variant Interpretation Guidelines for Genes Associated with Inherited Myeloid Neoplasms Blood. 132: 5849-5849. DOI: 10.1182/Blood-2018-99-118979 |
0.345 |
|
2018 |
Brady LK, Soong D, Lind EF, Kosaka Y, Lamble AJ, Schaffer M, Hodkinson BP, Lefave C, Laderas T, McWeeney SK, Adams H, Abraham Y, Safabakhsh P, Tyner JW, Druker BJ, et al. Immunogenomic Exploration of the Acute Myeloid Leukemia Microenvironment Identifies Determinants of T-Cell Fitness Blood. 132: 2750-2750. DOI: 10.1182/Blood-2018-99-118424 |
0.323 |
|
2018 |
Brown AL, Armstrong M, Lawrence D, Wang P, Arts P, Duployez N, Churpek J, Tawana K, Degelman E, Natsoulis G, Guzman ML, Patnaik MM, Shimamura A, Cantor AB, Ripperger T, ... ... McWeeney SK, et al. Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB Blood. 132: 5241-5241. DOI: 10.1182/Blood-2018-99-118017 |
0.308 |
|
2018 |
Kurtz SE, Eide CA, Dubey NP, Kaempf A, McWeeney SK, Tognon CE, Mori M, Druker BJ, Tyner JW, Agarwal A. Combining p38MAPK Inhibitors with a Second Targeted Agent Enhances Blockade of Inflammatory Signaling-Mediated Survival in Acute Myeloid Leukemia Cells Blood. 132: 2726-2726. DOI: 10.1182/Blood-2018-99-117537 |
0.332 |
|
2018 |
Kurtz SE, Watanabe-Smith K, Bottomly D, Wilmot B, Mcweeney S, Local A, Zhang H, Howell S, Rice W, Druker BJ, Tyner JW. Abstract 791: CG'806, a first-in-class pan-FLT3/pan-BTK inhibitor, demonstrates superiority to other FLT3 and BTK inhibitors against primary patient samples Cancer Research. 78: 791-791. DOI: 10.1158/1538-7445.Am2018-791 |
0.341 |
|
2017 |
Graham JB, Swarts JL, Mooney M, Choonoo G, Jeng S, Miller DR, Ferris MT, McWeeney S, Lund JM. Extensive Homeostatic T Cell Phenotypic Variation within the Collaborative Cross. Cell Reports. 21: 2313-2325. PMID 29166619 DOI: 10.1016/J.Celrep.2017.10.093 |
0.31 |
|
2017 |
Davis LE, Jeng S, Svalina MN, Huang E, Pittsenbarger J, Cantor EL, Berlow N, Seguin B, Mansoor A, McWeeney SK, Keller C. Integration of genomic, transcriptomic and functional profiles of aggressive osteosarcomas across multiple species. Oncotarget. 8: 76241-76256. PMID 29100308 DOI: 10.18632/Oncotarget.19532 |
0.336 |
|
2017 |
Zhang H, Means S, Schultz AR, Watanabe-Smith K, Medeiros BC, Bottomly D, Wilmot B, McWeeney SK, Kükenshöner T, Hantschel O, Tyner JW. Unpaired extracellular cysteine mutations of CSF3R mediate gain or loss of function. Cancer Research. PMID 28652245 DOI: 10.1158/0008-5472.Can-17-1052 |
0.3 |
|
2017 |
Green R, Wilkins C, Thomas S, Sekine A, Hendrick DM, Voss K, Ireton RC, Mooney M, Go JT, Choonoo G, Jeng S, de Villena FP, Ferris MT, McWeeney S, Gale M. Oas1b-dependent Immune Transcriptional Profiles of West Nile Virus Infection in the Collaborative Cross. G3 (Bethesda, Md.). 7: 1665-1682. PMID 28592649 DOI: 10.1534/G3.117.041624 |
0.311 |
|
2017 |
Zhang H, Schultz AR, Luty S, Rofelty A, Su Y, Means S, Bottomly D, Wilmot B, McWeeney SK, Tyner JW. Characterization of the leukemogenic potential of distal cytoplasmic CSF3R truncation and missense mutations. Leukemia. PMID 28439110 DOI: 10.1038/Leu.2017.126 |
0.303 |
|
2017 |
Iancu OD, Colville A, Walter NA, Darakjian P, Oberbeck DL, Daunais JB, Zheng CL, Searles RP, McWeeney SK, Grant KA, Hitzemann R. On the relationships in rhesus macaques between chronic ethanol consumption and the brain transcriptome. Addiction Biology. PMID 28247455 DOI: 10.1111/Adb.12501 |
0.302 |
|
2017 |
Colville AM, Iancu OD, Oberbeck DL, Darakjian P, Zheng CL, Walter NA, Harrington CA, Searles RP, McWeeney S, Hitzemann RJ. Effects of selection for ethanol preference on gene expression in the nucleus accumbens of HS-CC mice. Genes, Brain, and Behavior. PMID 28058793 DOI: 10.1111/Gbb.12367 |
0.332 |
|
2017 |
Kurtz SE, Wilmot B, Mcweeney S, Local A, Zhang H, Howell S, Rice W, Druker BJ, Tyner JW. CG '806, a First-in-Class Pan-FLT3/BTK Inhibitor, Exhibits Potent Growth Inhibition As a Single Agent and in Combination with a BET Bromodomain Inhibitor or a Bcl2 Inhibitor on Primary AML and CLL Patient Samples Blood. 130: 4626-4626. DOI: 10.1182/Blood.V130.Suppl_1.4626.4626 |
0.358 |
|
2017 |
Kurtz SE, Wilmot B, McWeeney S, Vellanki A, Local A, Benbatoul K, Folger P, Sheng S, Zhang H, Howell SB, Rice WG, Druker BJ, Tyner JW. Abstract 44: CG′806, a first-in-class FLT3/BTK inhibitor, exhibits potent activity against AML patient samples with mutant or wild type FLT3, as well as other hematologic malignancy subtypes Clinical Cancer Research. 23: 44-44. DOI: 10.1158/1557-3265.Hemmal17-44 |
0.335 |
|
2017 |
Ouyang X, Barling A, Lesch A, Tyner J, Jeng S, Zheng C, Courtneidge SA, McWeeney S, Kulesz-Martin M. Abstract 78: Inhibiting anaplastic lymphoma kinase (ALK) overcomes epidermal growth factor receptor (EGFR) inhibitor resistance in head and neck squamous cell carcinoma (HNSCC) patient-derived models Clinical Cancer Research. 23: 78-78. DOI: 10.1158/1557-3265.Aacrahns17-78 |
0.313 |
|
2016 |
Mooney MA, McWeeney SK, Faraone S, Hinney A, Hebebrand J, Nigg JT, Wilmot B. Pathway analysis in attention deficit hyperactivity disorder: An ensemble approach. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 27004716 DOI: 10.1002/Ajmg.B.32446 |
0.305 |
|
2016 |
Eiring AM, Khorashad JS, Agarwal A, Mason CC, Bell R, Senina A, Pomicter AD, Yu F, Redwine HM, Bowler AD, Clair PM, Tantravahi SK, McWeeney SK, Druker BJ, Stirewalt DL, et al. MS4A3: A New Player in Leukemic Stem Cell Survival in Chronic Myeloid Leukemia Blood. 128: 934-934. DOI: 10.1182/Blood.V128.22.934.934 |
0.302 |
|
2016 |
Degnin M, Tognon CE, Eide CA, Wilmot B, McWeeney SK, Bottomly D, Smith R, Druker BJ. High-Throughput Validation of Mutations Identified in Primary Leukemia Cells Blood. 128: 4725-4725. DOI: 10.1182/Blood.V128.22.4725.4725 |
0.331 |
|
2016 |
Lamble A, Kosaka Y, Huang F, Sasser AK, Adams H, Tognon CE, Laderas T, McWeeney SK, Loriaux MM, Tyner JW, Druker BJ, Lind EF. Enhanced VISTA Expression in a Subset of Patients with Acute Myeloid Leukemia Blood. 128: 4056-4056. DOI: 10.1182/Blood.V128.22.4056.4056 |
0.31 |
|
2016 |
Khanna V, Eide CA, Tognon CE, Maxson JE, Wilmot B, Bottomly D, McWeeney SK, Druker BJ, Tyner JW. Recurrent Pathogenic Cyclin D2 Mutations in Myeloid Malignancies Blood. 128: 2734-2734. DOI: 10.1182/Blood.V128.22.2734.2734 |
0.355 |
|
2016 |
Eide CA, Bottomly D, Savage SL, White L, Wilmot B, Reister Schultz AM, Uchida KA, Agarwal A, Traer E, Beppu L, Sala-Torra O, Radich JP, Eickelberg G, Press RD, Loriaux MM, ... ... McWeeney SK, et al. Characterization of the Genomic Landscape of BCR-ABL1 Kinase-Independent Mechanisms of Resistance to ABL1 Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia Blood. 128: 1119-1119. DOI: 10.1182/Blood.V128.22.1119.1119 |
0.343 |
|
2015 |
Maxson JE, Abel ML, Wang J, Deng X, Reckel S, Luty SB, Sun H, Gorenstein J, Hughes SB, Bottomly D, Wilmot B, McWeeney SK, Radich J, Hantschel O, Middleton RE, et al. Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis. Cancer Research. PMID 26677978 DOI: 10.1158/0008-5472.Can-15-0817 |
0.37 |
|
2015 |
Maxson JE, Davare MA, Luty SB, Eide CA, Chang BH, Loriaux MM, Tognon CE, Bottomly D, Wilmot B, McWeeney SK, Druker BJ, Tyner JW. Therapeutically Targetable ALK Mutations in Leukemia. Cancer Research. 75: 2146-50. PMID 26032424 DOI: 10.1158/0008-5472.Can-14-1576 |
0.323 |
|
2015 |
Iancu OD, Colville A, Oberbeck D, Darakjian P, McWeeney SK, Hitzemann R. Cosplicing network analysis of mammalian brain RNA-Seq data utilizing WGCNA and Mantel correlations. Frontiers in Genetics. 6: 174. PMID 26029240 DOI: 10.3389/Fgene.2015.00174 |
0.327 |
|
2015 |
Edwards DK, Rofelty A, Agarwal A, Kurtz SE, Traer E, Lee P, Chantry D, Loriaux M, Druker BJ, McWeeney SK, Tyner JW. CSF1R Inhibition Targets AML Cells By Depleting Supportive Microenvironmental Signal from CD14+ Monocytes Blood. 126: 3824-3824. DOI: 10.1182/Blood.V126.23.3824.3824 |
0.338 |
|
2015 |
Zhang H, Watanabe-Smith KM, Bottomly D, Wilmot B, McWeeney SK, Kantarjian HM, Ho J, Davis J, Pond B, Borthakur G, Ramachandran A, Cortes JE, Collins R, Tyner JW. Exome Sequencing Informs Mechanisms of Clinical Resistance to the FLT3-D835 Inhibitor Crenolanib Blood. 126: 2468-2468. DOI: 10.1182/Blood.V126.23.2468.2468 |
0.323 |
|
2015 |
Savage SL, Eide CA, Concannon KF, Bottomly D, Wilmot B, McWeeney SK, Maxson JE, Tyner JW, Tognon CE, Druker BJ. Activating Mutations of Insulin Receptor Substrate 2 (IRS2) in Patients with Tyrosine Kinase Inhibitor-Refractory Chronic Myeloid Leukemia Blood. 126: 2461-2461. DOI: 10.1182/Blood.V126.23.2461.2461 |
0.347 |
|
2015 |
Eiring AM, Khorashad JS, Agarwal A, Mason CC, Yu F, Redwine HM, Bowler AD, Gantz KC, Reynolds KR, Clair PM, Anderson DJ, Tantravahi SK, McWeeney SK, Druker BJ, Stirewalt DL, et al. MS4A3 Improves Imatinib Response and Survival in BCR-ABL1 Primary TKI Resistance and in Blastic Transformation of Chronic Myeloid Leukemia Blood. 126: 14-14. DOI: 10.1182/Blood.V126.23.14.14 |
0.332 |
|
2015 |
Kurtz SE, Bottomly D, Wilmot B, McWeeney SK, Rice W, Howell SB, Vellanki A, Druker BJ, Tyner JW. Broad Activity of Apto-253 in AML and Other Hematologic Malignancies Correlates with KLF4 Expression Level Blood. 126: 1358-1358. DOI: 10.1182/Blood.V126.23.1358.1358 |
0.331 |
|
2014 |
Mooney MA, Nigg JT, McWeeney SK, Wilmot B. Functional and genomic context in pathway analysis of GWAS data. Trends in Genetics : Tig. 30: 390-400. PMID 25154796 DOI: 10.1016/J.Tig.2014.07.004 |
0.322 |
|
2014 |
Yao H, Goldman DC, Nechiporuk T, Kawane S, McWeeney SK, Tyner JW, Fan G, Kerenyi MA, Orkin SH, Fleming WH, Mandel G. Corepressor Rcor1 is essential for murine erythropoiesis. Blood. 123: 3175-84. PMID 24652990 DOI: 10.1182/Blood-2013-11-538678 |
0.318 |
|
2014 |
Gibbs DL, Gralinski L, Baric RS, McWeeney SK. Multi-omic network signatures of disease. Frontiers in Genetics. 4: 309. PMID 24432028 DOI: 10.3389/Fgene.2013.00309 |
0.312 |
|
2014 |
Bottomly D, Wilmot B, McWeeney SK. Oligomask: A framework for assessing and removing the effect of genetic variants on microarray probes R Journal. 6: 159-163. DOI: 10.32614/Rj-2014-018 |
0.314 |
|
2014 |
Eide CA, Savage SL, Agarwal A, Bottomly D, Wilmot B, McWeeney SK, Kurtz SE, O'Hare T, Deininger MW, Loriaux MM, Tognon CE, Tyner JW, Druker BJ. Activating Mutations Observed in De Novo Acute Myeloid Leukemia Are Also Present in a Subset of Philadelphia Chromosome (Ph)-Positive Leukemia Patients with BCR-ABL1-Independent Resistance to ABL1 Kinase Inhibitors Blood. 124: 4514-4514. DOI: 10.1182/Blood.V124.21.4514.4514 |
0.334 |
|
2014 |
Eiring AM, Agarwal A, Khorashad JS, Mason CC, Anderson DJ, Yu F, Redwine HM, Gantz KC, Reynolds KR, McWeeney SK, Druker BJ, O'Hare T, Deininger MW. The Tumor Suppressors, MS4A3 and G0S2, Are Downregulated in CML Cells with BCR-ABL1 Kinase-Independent Resistance Blood. 124: 1786-1786. DOI: 10.1182/Blood.V124.21.1786.1786 |
0.345 |
|
2014 |
Betzing C, McWeeney S, Boudreau E, Thomas C. Identification of Critical Pathways Altered by Radiation Exposure and Drug Target Analysis International Journal of Radiation Oncology*Biology*Physics. 90: S822. DOI: 10.1016/J.Ijrobp.2014.05.2368 |
0.321 |
|
2013 |
Bottomly D, Ryabinin PA, Tyner JW, Chang BH, Loriaux MM, Druker BJ, McWeeney SK, Wilmot B. Comparison of methods to identify aberrant expression patterns in individual patients: augmenting our toolkit for precision medicine. Genome Medicine. 5: 103. PMID 24286512 DOI: 10.1186/Gm509 |
0.336 |
|
2013 |
Belknap JK, McWeeney S, Reed C, Burkhart-Kasch S, McKinnon CS, Li N, Baba H, Scibelli AC, Hitzemann R, Phillips TJ. Genetic factors involved in risk for methamphetamine intake and sensitization. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 24: 446-58. PMID 24217691 DOI: 10.1007/S00335-013-9484-9 |
0.324 |
|
2013 |
Gralinski LE, Bankhead A, Jeng S, Menachery VD, Proll S, Belisle SE, Matzke M, Webb-Robertson BJ, Luna ML, Shukla AK, Ferris MT, Bolles M, Chang J, Aicher L, Waters KM, ... ... McWeeney S, et al. Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury. Mbio. 4. PMID 23919993 DOI: 10.1128/Mbio.00271-13 |
0.304 |
|
2013 |
Iancu OD, Oberbeck D, Darakjian P, Kawane S, Erk J, McWeeney S, Hitzemann R. Differential network analysis reveals genetic effects on catalepsy modules. Plos One. 8: e58951. PMID 23555609 DOI: 10.1371/Journal.Pone.0058951 |
0.328 |
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2013 |
Iancu OD, Oberbeck D, Darakjian P, Metten P, McWeeney S, Crabbe JC, Hitzemann R. Selection for drinking in the dark alters brain gene coexpression networks. Alcoholism, Clinical and Experimental Research. 37: 1295-303. PMID 23550792 DOI: 10.1111/Acer.12100 |
0.357 |
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2013 |
Ferris MT, Aylor DL, Bottomly D, Whitmore AC, Aicher LD, Bell TA, Bradel-Tretheway B, Bryan JT, Buus RJ, Gralinski LE, Haagmans BL, McMillan L, Miller DR, Rosenzweig E, Valdar W, ... ... McWeeney SK, et al. Modeling host genetic regulation of influenza pathogenesis in the collaborative cross. Plos Pathogens. 9: e1003196. PMID 23468633 DOI: 10.1371/Journal.Ppat.1003196 |
0.321 |
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2013 |
Sims AC, Tilton SC, Menachery VD, Gralinski LE, Schäfer A, Matzke MM, Webb-Robertson BJ, Chang J, Luna ML, Long CE, Shukla AK, Bankhead AR, Burkett SE, Zornetzer G, Tseng CT, ... ... McWeeney S, et al. Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells. Journal of Virology. 87: 3885-902. PMID 23365422 DOI: 10.1128/Jvi.02520-12 |
0.321 |
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2013 |
Bottomly D, Wilmot B, Tyner JW, Eide CA, Loriaux MM, Druker BJ, McWeeney SK. HitWalker: variant prioritization for personalized functional cancer genomics. Bioinformatics (Oxford, England). 29: 509-10. PMID 23303510 DOI: 10.1093/Bioinformatics/Btt003 |
0.32 |
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2013 |
Eide CA, Savage SL, Bryant J, Agarwal A, Bottomly D, Wilmot B, McWeeney SK, O'Hare T, Deininger MW, Loriaux MM, Tognon CE, Tyner JW, Druker BJ. Philadelphia Chromosome (Ph)-Positive Leukemia Patients Who Fail ABL1 Tyrosine Kinase Inhibitors Without BCR-ABL1 Kinase Domain Point Mutations Demonstrate Sensitivity To PI3-K/AKT Inhibitors Blood. 122: 3994-3994. DOI: 10.1182/Blood.V122.21.3994.3994 |
0.32 |
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2013 |
Maxson JE, Gotlib J, Pollyea DA, Fleischman AG, Agarwal A, Luty SB, Abel M, Eide CA, Bottomly D, Wilmot B, McWeeney SK, Tognon CE, Collins RH, Pond JB, Goueli B, et al. The CSF3R T618I Mutation Found In Chronic Neutrophilic Leukemia Removes An O-Linked Glycosylation Site and Increases Receptor Dimerization Blood. 122: 270-270. DOI: 10.1182/Blood.V122.21.270.270 |
0.307 |
|
2013 |
Maxson J, Gotlib J, Pollyea D, Fleischman A, Eide C, Bottomly D, Wilmot B, McWeeney S, Tognon C, Pond JB, Collins R, Deininger M, Chang B, Loriaux M, Druker B, et al. Abstract 2282: Rapid identification of targetable CSF3R mutations that define neutrophilic leukemia by combining functional and genomic screens. Cancer Research. 73: 2282-2282. DOI: 10.1158/1538-7445.Am2013-2282 |
0.349 |
|
2012 |
Iancu OD, Darakjian P, Kawane S, Bottomly D, Hitzemann R, McWeeney S. Detection of expression quantitative trait Loci in complex mouse crosses: impact and alleviation of data quality and complex population substructure. Frontiers in Genetics. 3: 157. PMID 22969789 DOI: 10.3389/Fgene.2012.00157 |
0.313 |
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2012 |
Bottomly D, Ferris MT, Aicher LD, Rosenzweig E, Whitmore A, Aylor DL, Haagmans BL, Gralinski LE, Bradel-Tretheway BG, Bryan JT, Threadgill DW, de Villena FP, Baric RS, Katze MG, Heise M, ... McWeeney SK, et al. Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice. G3 (Bethesda, Md.). 2: 213-21. PMID 22384400 DOI: 10.1534/G3.111.001800 |
0.313 |
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2012 |
Iraqi FA, Mahajne M, Salaymah Y, Sandovski H, Tayem H, Vered K, Balmer L, Hall M, Manship G, Morahan G, Pettit K, Scholten J, Tweedie K, Wallace A, Weerasekera L, ... ... Mcweeney SK, et al. The genome architecture of the collaborative cross mouse genetic reference population Genetics. 190: 389-401. PMID 22345608 DOI: 10.1534/Genetics.111.132639 |
0.302 |
|
2012 |
Iancu OD, Darakjian P, Malmanger B, Walter NA, McWeeney S, Hitzemann R. Gene networks and haloperidol-induced catalepsy. Genes, Brain, and Behavior. 11: 29-37. PMID 21967164 DOI: 10.1111/J.1601-183X.2011.00736.X |
0.308 |
|
2012 |
Maxson JE, Gotlib J, Fleischman AG, Eide CA, Bottomly D, Wilmot B, McWeeney S, Tognon C, Loriaux MM, Druker BJ, Tyner JW. A Truncation Mutant of CSF3R, Identified As a Novel Driver in De Novo Myeloid Leukemia, Signals Through TNK2, and Is Responsive to Dasatinib. Blood. 120: 2412-2412. DOI: 10.1182/Blood.V120.21.2412.2412 |
0.36 |
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2011 |
Laderas TG, Walter NA, Mooney M, Vartanian K, Darakjian P, Buck K, Harrington CA, Belknap J, Hitzemann R, McWeeney SK. Computational detection of alternative exon usage. Frontiers in Neuroscience. 5: 69. PMID 21625610 DOI: 10.3389/Fnins.2011.00069 |
0.302 |
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2011 |
Fei SS, Wilmarth PA, Hitzemann RJ, McWeeney SK, Belknap JK, David LL. Protein database and quantitative analysis considerations when integrating genetics and proteomics to compare mouse strains. Journal of Proteome Research. 10: 2905-12. PMID 21553863 DOI: 10.1021/Pr200133P |
0.306 |
|
2011 |
Bottomly D, Walter NA, Hunter JE, Darakjian P, Kawane S, Buck KJ, Searles RP, Mooney M, McWeeney SK, Hitzemann R. Evaluating gene expression in C57BL/6J and DBA/2J mouse striatum using RNA-Seq and microarrays. Plos One. 6: e17820. PMID 21455293 DOI: 10.1371/Journal.Pone.0017820 |
0.306 |
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2010 |
Iancu OD, Darakjian P, Walter NA, Malmanger B, Oberbeck D, Belknap J, McWeeney S, Hitzemann R. Genetic diversity and striatal gene networks: focus on the heterogeneous stock-collaborative cross (HS-CC) mouse. Bmc Genomics. 11: 585. PMID 20959017 DOI: 10.1186/1471-2164-11-585 |
0.316 |
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2010 |
McWeeney SK, Pemberton LC, Loriaux MM, Vartanian K, Willis SG, Yochum G, Wilmot B, Turpaz Y, Pillai R, Druker BJ, Snead JL, MacPartlin M, O'Brien SG, Melo JV, Lange T, et al. A gene expression signature of CD34+ cells to predict major cytogenetic response in chronic-phase chronic myeloid leukemia patients treated with imatinib. Blood. 115: 315-25. PMID 19837975 DOI: 10.1182/Blood-2009-03-210732 |
0.311 |
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2009 |
Walter NA, Bottomly D, Laderas T, Mooney MA, Darakjian P, Searles RP, Harrington CA, McWeeney SK, Hitzemann R, Buck KJ. High throughput sequencing in mice: a platform comparison identifies a preponderance of cryptic SNPs. Bmc Genomics. 10: 379. PMID 19686600 DOI: 10.1186/1471-2164-10-379 |
0.33 |
|
2009 |
McWeeney S, Yochum G, Pemberton LC, Loriaux M, Vartanian K, Willis SG, Wilmot B, Turpaz Y, Pillai R, partlin MM, Snead J, Druker BJ, O'Brien SG, Melo JV, Lange T, et al. A Gene Expression Signature of CD34+ Cells to Predict Major Cytogenetic Response in Chronic Phase Chronic Myeloid Leukemia Patients Treated with Imatinib: Potential Involvement of Beta-Catenin in Drug Resistance. Blood. 114: 508-508. DOI: 10.1182/Blood.V114.22.508.508 |
0.337 |
|
2008 |
Hofstetter JR, Hitzemann RJ, Belknap JK, Walter NA, McWeeney SK, Mayeda AR. Characterization of the quantitative trait locus for haloperidol-induced catalepsy on distal mouse chromosome 1. Genes, Brain, and Behavior. 7: 214-23. PMID 17696997 DOI: 10.1111/J.1601-183X.2007.00340.X |
0.334 |
|
2007 |
Walter NA, McWeeney SK, Peters ST, Belknap JK, Hitzemann R, Buck KJ. SNPs matter: impact on detection of differential expression. Nature Methods. 4: 679-80. PMID 17762873 DOI: 10.1038/Nmeth0907-679 |
0.304 |
|
2007 |
Keller DM, McWeeney S, Arsenlis A, Drouin J, Wright CV, Wang H, Wollheim CB, White P, Kaestner KH, Goodman RH. Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy. The Journal of Biological Chemistry. 282: 32084-92. PMID 17761679 DOI: 10.1074/Jbc.M700899200 |
0.305 |
|
2007 |
Agarwal SK, Impey S, McWeeney S, Scacheri PC, Collins FS, Goodman RH, Spiegel AM, Marx SJ. Distribution of menin-occupied regions in chromatin specifies a broad role of menin in transcriptional regulation. Neoplasia (New York, N.Y.). 9: 101-7. PMID 17356705 DOI: 10.1593/Neo.06706 |
0.33 |
|
2007 |
McWeeney SK, Pemberton LC, Harrington CA, Druker BJ, Deininger MW. A Transcriptomal Profile for Predicting Complete Cytogenetic Response (CCR) in Chronic Phase CML Patients Treated with Imatinib. Blood. 110: 1007-1007. DOI: 10.1182/Blood.V110.11.1007.1007 |
0.339 |
|
2006 |
Yanai I, Korbel JO, Boue S, McWeeney SK, Bork P, Lercher MJ. Similar gene expression profiles do not imply similar tissue functions. Trends in Genetics : Tig. 22: 132-8. PMID 16480787 DOI: 10.1016/J.Tig.2006.01.006 |
0.301 |
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2006 |
Bagby GC, McWeeney S, Yates J, Park B, Rathbun RK, Pilonetto D, Harris R, Wagner J, Harrington C, Mori M, Pasquini R, Clapp DW. Comparative Functional Genomic Analysis of Myelodysplasia (MDS) in Fanconi Anemia (FA). Blood. 108: 2636-2636. DOI: 10.1182/Blood.V108.11.2636.2636 |
0.352 |
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2005 |
Xiao XQ, Grove KL, Lau SY, McWeeney S, Smith MS. Deoxyribonucleic acid microarray analysis of gene expression pattern in the arcuate nucleus/ventromedial nucleus of hypothalamus during lactation. Endocrinology. 146: 4391-8. PMID 16002521 DOI: 10.1210/En.2005-0561 |
0.306 |
|
2005 |
Willis SG, Lange T, Demehri S, Otto S, Crossman L, Niederwieser D, Stoffregen EP, McWeeney S, Kovacs I, Park B, Druker BJ, Deininger MW. High-sensitivity detection of BCR-ABL kinase domain mutations in imatinib-naive patients: correlation with clonal cytogenetic evolution but not response to therapy. Blood. 106: 2128-37. PMID 15914554 DOI: 10.1182/Blood-2005-03-1036 |
0.313 |
|
2005 |
Crossman LC, Loriaux M, Vartanian K, Turpaz Y, Pillai R, O’Brien SG, Druker BJ, McWeeney SK, Harrington CA, Deininger MW. Gene Expression Profiling of CML CD34+ Cells Prior to Imatinib Therapy Reveals Differences between Patients with and without Subsequent Complete Cytogenetic Response. Blood. 106: 1222-1222. DOI: 10.1182/Blood.V106.11.1222.1222 |
0.347 |
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2004 |
Impey S, McCorkle SR, Cha-Molstad H, Dwyer JM, Yochum GS, Boss JM, McWeeney S, Dunn JJ, Mandel G, Goodman RH. Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions. Cell. 119: 1041-54. PMID 15620361 DOI: 10.1016/J.Cell.2004.10.032 |
0.309 |
|
2004 |
Hitzemann R, Reed C, Malmanger B, Lawler M, Hitzemann B, Cunningham B, McWeeney S, Belknap J, Harrington C, Buck K, Phillips T, Crabbe J. On the integration of alcohol-related quantitative trait loci and gene expression analyses. Alcoholism, Clinical and Experimental Research. 28: 1437-48. PMID 15597075 DOI: 10.1097/01.Alc.0000139827.86749.Da |
0.331 |
|
2004 |
Bagby G, Yates J, McWeeney S, Park B, Rathbun K, Pilonetto D, Harris R, Wagner J, Pals G, Lau SY, Harrington C, Mori M, Pasquini R. Clonal Evolution of Fanconi Anemia (FA) Stem Cells Results from Clonal Adaptation and Clonal Selection. A Report from the International Fanconi Anemia Transcriptome Consortium. Blood. 104: 3416-3416. DOI: 10.1182/Blood.V104.11.3416.3416 |
0.33 |
|
2004 |
Deininger MW, Willis S, Lange T, McWeeney S, Otto S, Druker BJ. Detection of Imatinib-Resistant BCR-ABL Mutants in Drug-Naïve Patients: Correlation with Disease Phase and Clonal Evolution but Not with Response to Treatment. Blood. 104: 273-273. DOI: 10.1182/Blood.V104.11.273.273 |
0.326 |
|
1999 |
Valdes AM, McWeeney SK, Meyer D, Nelson MP, Thomson G. Locus and population specific evolution in HLA class II genes. Annals of Human Genetics. 63: 27-43. PMID 10738519 DOI: 10.1046/J.1469-1809.1999.6310027.X |
0.605 |
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1999 |
Chen JJ, Hollenbach JA, Trachtenberg EA, Just JJ, Carrington M, Rønningen KS, Begovich A, King MC, McWeeney S, Mack SJ, Erlich HA, Thomson G. Hardy-Weinberg testing for HLA class II (DRB1, DQA1, DQB1, AND DPB1) loci in 26 human ethnic groups Tissue Antigens. 54: 533-542. PMID 10674966 DOI: 10.1034/J.1399-0039.1999.540601.X |
0.49 |
|
1999 |
Valdes AM, McWeeney SK, Thomson G. Evidence for linkage and association to alcohol dependence on chromosome 19. Genetic Epidemiology. 17: S367-72. PMID 10597464 DOI: 10.1002/Gepi.1370170762 |
0.485 |
|
1999 |
Salamon H, Klitz W, Easteal S, Gao X, Erlich HA, Fernandez-Viña M, Trachtenberg EA, McWeeney SK, Nelson MP, Thomson G. Evolution of HLA class II molecules: Allelic and amino acid site variability across populations. Genetics. 152: 393-400. PMID 10224269 |
0.426 |
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