Philip A. Gruppuso - Publications

Affiliations: 
Molecular Biology, Cell Biology and Biochemistry Brown University, Providence, RI 

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Year Citation  Score
2022 Raigani S, Santiago J, Ohman A, Heaney M, Baptista S, Coe TM, de Vries RJ, Rosales I, Shih A, Markmann JF, Gruppuso P, Uygun K, Sanders J, Yeh H. Pan-caspase inhibition during normothermic machine perfusion of discarded livers mitigates innate immune responses. Frontiers in Immunology. 13: 940094. PMID 35958587 DOI: 10.3389/fimmu.2022.940094  0.626
2021 Ohman A, Raigani S, Santiago JC, Heaney MG, Boylan JM, Parry N, Carroll C, Baptista SG, Uygun K, Gruppuso PA, Sanders JA, Yeh H. Activation of autophagy during normothermic machine perfusion of discarded livers is associated with improved hepatocellular function. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 34730028 DOI: 10.1152/ajpgi.00266.2021  0.645
2021 Santiago JC, Boylan JM, Lemieux FA, Gruppuso PA, Sanders JA, Rand DM. Mitochondrial genotype alters the impact of rapamycin on the transcriptional response to nutrients in Drosophila. Bmc Genomics. 22: 213. PMID 33761878 DOI: 10.1186/s12864-021-07516-2  0.557
2019 Zabala V, Boylan JM, Thevenot P, Frank A, Senthoor D, Iyengar V, Kim H, Cohen A, Gruppuso PA, Sanders JA. Transcriptional changes during hepatic ischemia-reperfusion in the rat. Plos One. 14: e0227038. PMID 31891620 DOI: 10.1371/Journal.Pone.0227038  0.642
2019 Hodax JK, Quintos JB, Gruppuso PA, Chen Q, Desai S, Jayasuriya CT. Aggrecan is required for chondrocyte differentiation in ATDC5 chondroprogenitor cells. Plos One. 14: e0218399. PMID 31206541 DOI: 10.1371/Journal.Pone.0218399  0.349
2018 Chorzalska A, Morgan J, Ahsan N, Treaba DO, Olszewski AJ, Petersen M, Kingston N, Cheng Y, Lombardo K, Schorl C, Yu X, Zini R, Pacilli A, Tepper A, Coburn J, ... ... Gruppuso PA, et al. Bone marrow-specific loss of induces myeloproliferative neoplasm with features resembling human myelofibrosis. Blood. PMID 30213875 DOI: 10.1182/Blood-2018-05-848408  0.309
2018 Gruppuso PA, Boylan JM, Zabala V, Neretti N, Abshiru NA, Sikora JW, Doud EH, Camarillo JM, Thomas PM, Kelleher NL, Sanders JA. Stability of histone post-translational modifications in samples derived from liver tissue and primary hepatic cells. Plos One. 13: e0203351. PMID 30192817 DOI: 10.1371/Journal.Pone.0203351  0.622
2018 Hurley E, Zabala V, Boylan JM, Gruppuso PA, Sanders JA. Hepatic Gene Expression during the Perinatal Transition in the Rat. Gene Expression. PMID 29929573 DOI: 10.3727/105221618X15293258688953  0.66
2018 Chorzalska A, Ahsan N, Rao RSP, Roder K, Yu X, Morgan J, Tepper A, Hines S, Zhang P, Treaba DO, Zhao TC, Olszewski AJ, Reagan J, Liang O, Gruppuso PA, et al. Overexpression of Tpl2 is linked to imatinib resistance and activation of MEK-ERK and NF-κB pathways in a model of Chronic Myeloid Leukemia. Molecular Oncology. PMID 29485707 DOI: 10.1002/1878-0261.12186  0.329
2017 Boylan JM, Francois-Vaughan H, Gruppuso PA, Sanders JA. Engraftment and Repopulation Potential of Late Gestation Fetal Rat Hepatocytes. Transplantation. PMID 28749819 DOI: 10.1097/Tp.0000000000001882  0.694
2017 Adebayo Michael AO, Ahsan N, Zabala V, Francois-Vaughan H, Post S, Brilliant KE, Salomon AR, Sanders JA, Gruppuso PA. Proteomic analysis of laser capture microdissected focal lesions in a rat model of progenitor marker-positive hepatocellular carcinoma. Oncotarget. PMID 28199961 DOI: 10.18632/Oncotarget.15219  0.665
2016 Boylan JM, Sanders JA, Gruppuso PA. Regulation of Fetal Liver Growth in a Model of Diet Restriction in the Pregnant Rat. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00138.2016. PMID 27357801 DOI: 10.1152/Ajpregu.00138.2016  0.714
2016 Francois-Vaughan H, Adebayo AO, Brilliant KE, Parry NM, Gruppuso PA, Sanders JA. Persistent Effect of mTOR Inhibition on Preneoplastic Foci Progression and Gene Expression in a Rat Model of Hepatocellular Carcinoma. Carcinogenesis. PMID 26905589 DOI: 10.1093/Carcin/Bgw016  0.69
2016 Gruppuso PA, Sanders JA. Regulation of liver development: implications for liver biology across the lifespan. Journal of Molecular Endocrinology. PMID 26887388 DOI: 10.1530/Jme-15-0313  0.705
2015 Huse SM, Gruppuso PA, Boekelheide K, Sanders JA. Patterns of gene expression and DNA methylation in human fetal and adult liver. Bmc Genomics. 16: 981. PMID 26589361 DOI: 10.1186/S12864-015-2066-3  0.652
2015 Boylan JM, Salomon AR, Tantravahi U, Gruppuso PA. Adaptation of HepG2 cells to a steady-state reduction in the content of protein phosphatase 6 (PP6) catalytic subunit. Experimental Cell Research. 335: 224-37. PMID 25999147 DOI: 10.1016/J.Yexcr.2015.05.008  0.397
2015 Boylan JM, Sanders JA, Neretti N, Gruppuso PA. Profiling of the fetal and adult rat liver transcriptome and translatome reveals discordant regulation by the mechanistic target of rapamycin (mTOR). American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 309: R22-35. PMID 25924882 DOI: 10.1152/Ajpregu.00114.2015  0.719
2015 Adebayo AO, Zandbergen F, Kozul-Horvath CD, Gruppuso PA, Hamilton JW. Chronic exposure to low-dose arsenic modulates lipogenic gene expression in mice. Journal of Biochemical and Molecular Toxicology. 29: 1-9. PMID 25155036 DOI: 10.1002/Jbt.21600  0.357
2015 Francois-Vaughan H, Brilliant K, Adebayo AO, Parry NMA, Gruppuso PA, Sanders JA. Abstract B55: mTOR signaling is critical to the development and expansion of preneoplastic foci in a rodent model of progenitor-marker positive hepatocellular carcinoma Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Pi3K14-B55  0.658
2014 Spade DJ, McDonnell EV, Heger NE, Sanders JA, Saffarini CM, Gruppuso PA, De Paepe ME, Boekelheide K. Xenotransplantation models to study the effects of toxicants on human fetal tissues. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 101: 410-22. PMID 25477288 DOI: 10.1002/Bdrb.21131  0.611
2014 Garcia B, Francois-Vaughan H, Onikoyi O, Kostadinov S, De Paepe ME, Gruppuso PA, Sanders JA. Xenotransplantation of human fetal adipose tissue: a model of in vivo adipose tissue expansion and adipogenesis. Journal of Lipid Research. 55: 2685-91. PMID 25193996 DOI: 10.1194/Jlr.D052787  0.62
2014 Lamming DW, Demirkan G, Boylan JM, Mihaylova MM, Peng T, Ferreira J, Neretti N, Salomon A, Sabatini DM, Gruppuso PA. Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2). Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 300-15. PMID 24072782 DOI: 10.1096/Fj.13-237743  0.399
2014 Sanders JA, Gruppuso PA. Hepatic, pancreatic and biliary cancers Translation and Its Regulation in Cancer Biology and Medicine. 611-629. DOI: 10.1007/978-94-017-9078-9_30  0.582
2012 Demirkan G, Salomon AR, Gruppuso PA. Phosphoproteomic analysis of liver homogenates. Methods in Molecular Biology (Clifton, N.J.). 909: 151-63. PMID 22903715 DOI: 10.1007/978-1-61779-959-4_11  0.41
2012 Sanders JA, Brilliant KE, Clift D, Patel A, Cerretti B, Claro P, Mills DR, Hixson DC, Gruppuso PA. The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat. Experimental and Molecular Pathology. 93: 40-9. PMID 22525806 DOI: 10.1016/J.Yexmp.2012.04.002  0.694
2012 Sanders JA, Schorl C, Patel A, Sedivy JM, Gruppuso PA. Postnatal liver growth and regeneration are independent of c-myc in a mouse model of conditional hepatic c-myc deletion. Bmc Physiology. 12: 1. PMID 22397685 DOI: 10.1186/1472-6793-12-1  0.676
2011 Villa-Cuesta E, Boylan JM, Tatar M, Gruppuso PA. Resveratrol inhibits protein translation in hepatic cells. Plos One. 6: e29513. PMID 22242130 DOI: 10.1371/Journal.Pone.0029513  0.37
2011 Demirkan G, Yu K, Boylan JM, Salomon AR, Gruppuso PA. Phosphoproteomic profiling of in vivo signaling in liver by the mammalian target of rapamycin complex 1 (mTORC1). Plos One. 6: e21729. PMID 21738781 DOI: 10.1371/Journal.Pone.0021729  0.394
2011 Gruppuso PA, Boylan JM, Sanders JA. The physiology and pathophysiology of rapamycin resistance: implications for cancer. Cell Cycle (Georgetown, Tex.). 10: 1050-8. PMID 21389767 DOI: 10.4161/Cc.10.7.15230  0.684
2010 Temu TM, Wu KY, Gruppuso PA, Phornphutkul C. The mechanism of ascorbic acid-induced differentiation of ATDC5 chondrogenic cells. American Journal of Physiology. Endocrinology and Metabolism. 299: E325-34. PMID 20530736 DOI: 10.1152/Ajpendo.00145.2010  0.312
2010 Jimenez RH, Lee JS, Francesconi M, Castellani G, Neretti N, Sanders JA, Sedivy J, Gruppuso PA. Regulation of gene expression in hepatic cells by the mammalian Target of Rapamycin (mTOR). Plos One. 5: e9084. PMID 20140209 DOI: 10.1371/Journal.Pone.0009084  0.778
2009 Jimenez RH, Boylan JM, Lee JS, Francesconi M, Castellani G, Sanders JA, Gruppuso PA. Rapamycin response in tumorigenic and non-tumorigenic hepatic cell lines. Plos One. 4: e7373. PMID 19816606 DOI: 10.1371/Journal.Pone.0007373  0.776
2009 Kim MS, Wu KY, Auyeung V, Chen Q, Gruppuso PA, Phornphutkul C. Leucine restriction inhibits chondrocyte proliferation and differentiation through mechanisms both dependent and independent of mTOR signaling. American Journal of Physiology. Endocrinology and Metabolism. 296: E1374-82. PMID 19401455 DOI: 10.1152/Ajpendo.91018.2008  0.398
2008 Gruppuso PA, Tsai SW, Boylan JM, Sanders JA. Hepatic translation control in the late-gestation fetal rat. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R558-67. PMID 18565838 DOI: 10.1152/Ajpregu.00091.2008  0.712
2008 Sanders JA, Lakhani A, Phornphutkul C, Wu KY, Gruppuso PA. The effect of rapamycin on DNA synthesis in multiple tissues from late gestation fetal and postnatal rats. American Journal of Physiology. Cell Physiology. 295: C406-13. PMID 18550700 DOI: 10.1152/Ajpcell.00450.2007  0.692
2008 Yoo SJ, Jimenez RH, Sanders JA, Boylan JM, Brautigan DL, Gruppuso PA. The alpha4-containing form of protein phosphatase 2A in liver and hepatic cells. Journal of Cellular Biochemistry. 105: 290-300. PMID 18543252 DOI: 10.1002/Jcb.21830  0.773
2008 Phornphutkul C, Wu KY, Auyeung V, Chen Q, Gruppuso PA. mTOR signaling contributes to chondrocyte differentiation. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 702-12. PMID 18265001 DOI: 10.1002/Dvdy.21464  0.416
2007 Yoo SJ, Boylan JM, Brautigan DL, Gruppuso PA. Subunit composition and developmental regulation of hepatic protein phosphatase 2A (PP2A). Archives of Biochemistry and Biophysics. 461: 186-93. PMID 17391644 DOI: 10.1016/J.Abb.2007.02.019  0.635
2007 Sanders JA, Lakhani A, Gruppuso PA. Cell Proliferation in Multiple Rat Tissues In Vivo is Rapamycin Resistant The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A289-A  0.633
2007 Tsai S, Boylan JM, Sanders JA, Gruppuso PA. Hepatic translation control in late gestation fetal rats versus adult rats The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A288-D  0.654
2006 Phornphutkul C, Wu KY, Gruppuso PA. The role of insulin in chondrogenesis. Molecular and Cellular Endocrinology. 249: 107-15. PMID 16530934 DOI: 10.1016/J.Mce.2006.02.002  0.311
2006 Anand P, Gruppuso PA. Rapamycin inhibits liver growth during refeeding in rats via control of ribosomal protein translation but not cap-dependent translation initiation. The Journal of Nutrition. 136: 27-33. PMID 16365054 DOI: 10.1093/Jn/136.1.27  0.666
2006 Sanders JA, Gruppuso PA. Coordinated regulation of c-Myc and Max in rat liver development. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G145-55. PMID 16150871 DOI: 10.1152/Ajpgi.00545.2004  0.692
2005 Embree-Ku M, Gruppuso PA. The role of nuclear factor kappaB in late-gestation liver development in the rat. Hepatology (Baltimore, Md.). 42: 326-34. PMID 16025516 DOI: 10.1002/Hep.20796  0.432
2005 Boylan JM, Gruppuso PA. D-type cyclins and G1 progression during liver development in the rat. Biochemical and Biophysical Research Communications. 330: 722-30. PMID 15809057 DOI: 10.1016/J.Bbrc.2005.03.042  0.409
2005 Sanders JA, Gruppuso PA. Nucleolar localization of hepatic c-Myc: a potential mechanism for c-Myc regulation. Biochimica Et Biophysica Acta. 1743: 141-50. PMID 15777849 DOI: 10.1016/J.Bbamcr.2004.09.009  0.687
2005 Anand P, Gruppuso PA. The regulation of hepatic protein synthesis during fasting in the rat. The Journal of Biological Chemistry. 280: 16427-36. PMID 15716276 DOI: 10.1074/Jbc.M410576200  0.621
2005 Gruppuso PA, Boylan JM, Anand P, Bienieki TC. Effects of maternal starvation on hepatocyte proliferation in the late gestation fetal rat. Pediatric Research. 57: 185-91. PMID 15611345 DOI: 10.1203/01.Pdr.0000151646.55587.0F  0.676
2004 Phornphutkul C, Wu KY, Yang X, Chen Q, Gruppuso PA. Insulin-like growth factor-I signaling is modified during chondrocyte differentiation. The Journal of Endocrinology. 183: 477-86. PMID 15590974 DOI: 10.1677/Joe.1.05873  0.358
2004 Giannone PJ, Abu Dayyeh BK, Bienieki TC, Wands JR, Gruppuso PA. Targeted hepatic overexpression of human IRS-1: postnatal effects in the developing mouse. Biochimica Et Biophysica Acta. 1672: 112-9. PMID 15110093 DOI: 10.1016/J.Bbagen.2004.03.003  0.42
2004 Sanchez-Esteban J, Wang Y, Gruppuso PA, Rubin LP. Mechanical stretch induces fetal type II cell differentiation via an epidermal growth factor receptor-extracellular-regulated protein kinase signaling pathway. American Journal of Respiratory Cell and Molecular Biology. 30: 76-83. PMID 12829451 DOI: 10.1165/Rcmb.2003-0121Oc  0.376
2003 Khamzina L, Gruppuso PA, Wands JR. Insulin signaling through insulin receptor substrate 1 and 2 in normal liver development. Gastroenterology. 125: 572-85. PMID 12891559 DOI: 10.1016/S0016-5085(03)00893-X  0.382
2002 Boylan JM, Gruppuso PA. Insulin receptor substrate-1 is present in hepatocyte nuclei from intact rats. Endocrinology. 143: 4178-83. PMID 12399410 DOI: 10.1210/En.2002-220321  0.403
2002 Anand P, Boylan JM, Ou Y, Gruppuso PA. Insulin signaling during perinatal liver development in the rat. American Journal of Physiology. Endocrinology and Metabolism. 283: E844-52. PMID 12217903 DOI: 10.1152/Ajpendo.00111.2002  0.644
2001 Boylan JM, Anand P, Gruppuso PA. Ribosomal protein S6 phosphorylation and function during late gestation liver development in the rat. The Journal of Biological Chemistry. 276: 44457-63. PMID 11574531 DOI: 10.1074/Jbc.M103457200  0.679
2001 Tseng YT, Kopel R, Stabila JP, McGonnigal BG, Nguyen TT, Gruppuso PA, Padbury JF. Beta-adrenergic receptors (betaAR) regulate cardiomyocyte proliferation during early postnatal life. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1921-6. PMID 11532972 DOI: 10.1096/Fj.01-0151Com  0.397
2001 Morin MJ, Karr SM, Faris RA, Gruppuso PA. Developmental variability in expression and regulation of inducible nitric oxide synthase in rat intestine. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G552-9. PMID 11447036 DOI: 10.1152/Ajpgi.2001.281.2.G552  0.305
2000 Gruppuso PA, Boylan JM, Vaslet CA. Identification of candidate growth-regulating genes that are overexpressed in late gestation fetal liver in the rat. Biochimica Et Biophysica Acta. 1494: 242-7. PMID 11121581 DOI: 10.1016/S0167-4781(00)00244-X  0.477
2000 Awad MM, Sanders JA, Gruppuso PA. A potential role for p15(Ink4b) and p57(Kip2) in liver development. Febs Letters. 483: 160-4. PMID 11042273 DOI: 10.1016/S0014-5793(00)02108-6  0.728
2000 Phornphutkul C, Frick GP, Goodman HM, Berry SA, Gruppuso PA. Hepatic growth hormone signaling in the late gestation fetal rat. Endocrinology. 141: 3527-33. PMID 11014205 DOI: 10.1210/Endo.141.10.7702  0.461
2000 Awad MM, Enslen H, Boylan JM, Davis RJ, Gruppuso PA. Growth regulation via p38 mitogen-activated protein kinase in developing liver. The Journal of Biological Chemistry. 275: 38716-21. PMID 10995779 DOI: 10.1074/Jbc.M008040200  0.67
2000 Boney CM, Gruppuso PA, Faris RA, Frackelton AR. The critical role of Shc in insulin-like growth factor-I-mediated mitogenesis and differentiation in 3T3-L1 preadipocytes. Molecular Endocrinology (Baltimore, Md.). 14: 805-13. PMID 10847583 DOI: 10.1210/Mend.14.6.0487  0.349
2000 Gruppuso PA, Boylan JM. Hepatic epidermal growth factor-regulated mitogen-activated protein kinase kinase kinase activity in the rat: lack of identity with known forms of raf and MEKK. Febs Letters. 466: 200-4. PMID 10648842 DOI: 10.1016/S0014-5793(99)01792-5  0.403
1999 Gruppuso PA, Bienieki TC, Faris RA. The relationship between differentiation and proliferation in late gestation fetal rat hepatocytes. Pediatric Research. 46: 14-9. PMID 10400128 DOI: 10.1203/00006450-199907000-00003  0.414
1999 Gruppuso PA, Boylan JM. Late Gestation Fetal Rat Hepatocyte Proliferation Is Independent of p70 S6 Kinase Mitogenic Signaling: Implications for the Role of Growth Factors in Fetal Liver Development Pediatric Research. 45: 52A-52A. DOI: 10.1203/00006450-199904020-00314  0.453
1999 Gruppuso PA. Candidate Growth Regulating Genes in Late Gestation Fetal Rat Hepatocytes (FH): Identification by Subtractive Hybridization (SH) Pediatric Research. 45: 52A-52A. DOI: 10.1203/00006450-199904020-00313  0.381
1998 Boney CM, Smith RM, Gruppuso PA. Modulation of insulin-like growth factor I mitogenic signaling in 3T3-L1 preadipocyte differentiation. Endocrinology. 139: 1638-44. PMID 9528944 DOI: 10.1210/Endo.139.4.5920  0.337
1998 Boylan JM, Gruppuso PA. Uncoupling of hepatic, epidermal growth factor-mediated mitogen-activated protein kinase activation in the fetal rat. The Journal of Biological Chemistry. 273: 3784-90. PMID 9452512 DOI: 10.1074/Jbc.273.6.3784  0.409
1998 Gruppuso PA, Awad M, Boylan JM, Enslen H, Davis RJ. Signaling and Cell Cycle Regulation During Liver Development in the Rat• 269 Pediatric Research. 43: 48-48. DOI: 10.1203/00006450-199804001-00290  0.48
1997 Gruppuso PA, Awad M, Bienieki TC, Boylan JM, Fernando S, Faris RA. Modulation of mitogen-independent hepatocyte proliferation during the perinatal period in the rat. In Vitro Cellular & Developmental Biology. Animal. 33: 562-8. PMID 9282317 DOI: 10.1007/S11626-997-0099-X  0.659
1997 Leeds P, Kren BT, Boylan JM, Betz NA, Steer CJ, Gruppuso PA, Ross J. Developmental regulation of CRD-BP, an RNA-binding protein that stabilizes c-myc mRNA in vitro. Oncogene. 14: 1279-86. PMID 9178888 DOI: 10.1038/Sj.Onc.1201093  0.407
1997 Gruppuso PA, Boylan JM. A Novel Mechanism for Uncoupling of the Hepatic Ras/Mitogen ActivatedProtein Kinase (MAPK) Signaling Pathway in the Developing Rat. • 385 Pediatric Research. 41: 67-67. DOI: 10.1203/00006450-199704001-00405  0.353
1997 Gruppuso PA. The Relationship Between Proliferation and Differentiation in Fetal Rat Hepatocytes 257 Pediatric Research. 41: 45-45. DOI: 10.1203/00006450-199704001-00277  0.354
1997 Morin MJ, Faris RA, Gruppuso PA. Inducible Nitric Oxide Synthase (iNOS) in the Rat Intestine: An Immunohistochemical Study of Ontogeny in an Animal Model of Sepsis † 205 Pediatric Research. 41: 37-37. DOI: 10.1203/00006450-199704001-00225  0.317
1996 Lipeski LE, Boylan JM, Gruppuso PA. A comparison of epidermal growth factor receptor-mediated mitogenic signaling in response to transforming growth factor alpha and epidermal growth factor in cultured fetal rat hepatocytes. Biochemistry and Molecular Biology International. 39: 975-83. PMID 8866014 DOI: 10.1080/15216549600201122  0.33
1996 Boney CM, Fiedorek FT, Paul SR, Gruppuso PA. Regulation of preadipocyte factor-1 gene expression during 3T3-L1 cell differentiation. Endocrinology. 137: 2923-8. PMID 8770915 DOI: 10.1210/Endo.137.7.8770915  0.325
1996 Goto M, Chen H, Gruppuso PA, Zeller WP. TNFα SIGNALLING IS ALTERED BY PREVIOUS ENDOTOXIN EXPOSURE IN 10 DAY OLD RAT HEPATOCYTES. 1845 Pediatric Research. 39: 310-310. DOI: 10.1203/00006450-199604001-01869  0.314
1996 Mustafa-Kutana S, Boylan JM, Gruppuso PA. SELECTIVE HEPATIC INSULIN RESISTANCE IN GROWTH RETARDED FETAL RATS: STUDIES ON INSULIN RECEPTOR SUBSTRATE-1 (IRS-1) CONTENT AND TYROSINE PHOSPHORYLATION. • 551 Pediatric Research. 39: 94-94. DOI: 10.1203/00006450-199604001-00572  0.38
1996 Gruppuso PA, Awad M, Bienieki TC, Boylan JM, Fernando S. STUDIES ON THE ONTOGENY OF FETAL HEPATOCYTE (FH) PROLIFERATION DURING LATE GESTATION IN THE RAT. † 341 Pediatric Research. 39: 59-59. DOI: 10.1203/00006450-199604001-00361  0.373
1995 Gruppuso PA, Boylan JM. Developmental changes in the activity and cellular localization of hepatic casein kinase II in the rat. Journal of Cellular Biochemistry. 58: 65-72. PMID 7642724 DOI: 10.1002/Jcb.240580109  0.443
1994 Gruppuso PA, Boylan JM, Bienieki TC, Curran TR. Evidence for a direct hepatotrophic role for insulin in the fetal rat: implications for the impaired hepatic growth seen in fetal growth retardation. Endocrinology. 134: 769-75. PMID 8299572 DOI: 10.1210/Endo.134.2.8299572  0.375
1994 Boylan JM, Gruppuso PA. In vitro and in vivo regulation of hepatic mitogen-activated protein kinases in fetal rats. The American Journal of Physiology. 267: G1078-86. PMID 7810654 DOI: 10.1152/Ajpgi.1994.267.6.G1078  0.396
1993 Curran TR, Bahner RI, Oh W, Gruppuso PA. Mitogen-independent DNA synthesis by fetal rat hepatocytes in primary culture. Experimental Cell Research. 209: 53-7. PMID 8224006 DOI: 10.1006/Excr.1993.1284  0.347
1992 Gruppuso PA, Boylan JM, Carter PA, Madden JA, Raven T. Hepatic insulin and EGF receptor phosphorylation and dephosphorylation in fetal rats. The American Journal of Physiology. 262: E6-13. PMID 1733252 DOI: 10.1152/Ajpendo.1992.262.1.E6  0.362
1992 Boylan JM, Brautigan DL, Madden J, Raven T, Ellis L, Gruppuso PA. Differential regulation of multiple hepatic protein tyrosine phosphatases in alloxan diabetic rats. The Journal of Clinical Investigation. 90: 174-9. PMID 1321840 DOI: 10.1172/Jci115833  0.35
1991 Gruppuso PA, Walker TD, Carter PA. Ontogeny of hepatic type i insulin-like growth factor receptors in the rat Pediatric Research. 29: 226-230. PMID 1851980 DOI: 10.1203/00006450-199103000-00002  0.394
1991 Gruppuso PA, Boylan JM, Smiley BL, Fallon RJ, Brautigan DL. Hepatic protein tyrosine phosphatases in the rat. The Biochemical Journal. 274: 361-7. PMID 1848753 DOI: 10.1042/Bj2740361  0.348
1991 Gruppuso PA, Curran TR, Mead JE, Fausto N, Oh W. Fetal growth factors as determinants of intrauterine hepatic growth Diabetes. 40: 51-55. PMID 1660827 DOI: 10.2337/Diab.40.2.S51  0.387
1990 Fausto N, Mead JE, Gruppuso PA, Braun L. TGF-β in liver development, regeneration, and carcinogenesis Annals of the New York Academy of Sciences. 593: 231-242. PMID 2165377 DOI: 10.1111/J.1749-6632.1990.Tb16115.X  0.328
1990 Gruppuso PA. Hepatic protein Kinase-C and protein phosphatase type-2A in the fetal rat Pediatric Research. 27: 599-603. PMID 2162516 DOI: 10.1203/00006450-199006000-00014  0.411
1990 Gruppuso PA, Boylan JM, Posner BI, Faure R, Brautigan DL. Hepatic protein phosphotyrosine phosphatase. Dephosphorylation of insulin and epidermal growth factor receptors in normal and alloxan diabetic rats. The Journal of Clinical Investigation. 85: 1754-60. PMID 2161429 DOI: 10.1172/Jci114632  0.359
1989 Gruppuso PA. Effects of fetal hypoinsulinemia on fetal hepatic insulin binding in the rat Bba - Molecular Cell Research. 1010: 270-273. PMID 2643442 DOI: 10.1016/0167-4889(89)90172-9  0.346
1989 Gruppuso PA. Expression of hepatic transforming growth factor receptors during late gestation in the fetal rat Endocrinology. 125: 3037-3043. PMID 2555136 DOI: 10.1210/Endo-125-6-3037  0.375
1989 Gruppuso PA, Brautigan DL. Induction of hepatic glycogenesis in the fetal rat American Journal of Physiology - Endocrinology and Metabolism. 256: 19/1. PMID 2492154 DOI: 10.1152/Ajpendo.1989.256.1.E49  0.43
1987 Gruppuso PA, Brautigan DL, Schwartz R. INTRINSIC REGULATION OF GLYCOGEN PARTICLES: LIVER v. SKELETAL MUSCLE Pediatric Research. 21: 342A-342A. DOI: 10.1203/00006450-198704010-01047  0.33
1985 Domenech M, Gruppuso PA, Susa JB, Schwartz R. Induction in utero of hepatic glucose-6-phosphatase by fetal hypoinsulinemia Neonatology. 47: 92-98. PMID 2983786 DOI: 10.1159/000242096  0.373
1984 Susa JB, Gruppuso PA, Widness JA, Domenech M, Clemons GK, Sehgal P, Schwartz R. Chronic hyperinsulinemia in the fetal rhesus monkey: Effects of physiologic hyperinsulinemia on fetal substrates, hormones, and hepatic enzymes American Journal of Obstetrics and Gynecology. 150: 415-420. PMID 6385723 DOI: 10.1016/S0002-9378(84)80150-7  0.307
1983 Gruppuso PA, Susa JB, Domenech M, Cha CJ, Schwartz R. Chronic hyperglucagonemia in rats: Effects on insulin, substrates, and hepatic enzymes of intermediary metabolism Metabolism. 32: 911-918. PMID 6350815 DOI: 10.1016/0026-0495(83)90206-8  0.345
1981 Gruppuso PA, Migliori R, Susa JB, Schwartz R. Chronic maternal hyperinsulinemia and hypoglycemia. A model for experimental intrauterine growth retardation. Biology of the Neonate. 40: 113-20. PMID 7025925 DOI: 10.1159/000241479  0.314
Low-probability matches (unlikely to be authored by this person)
2004 Cerezo CS, Kulpa-Oliver V, Gruppuso PA, Morin MJ. Regulation of adolescent rat intestinal epithelial inducible nitric oxide synthase expression in endotoxin tolerance: modulation of signal transduction. Shock (Augusta, Ga.). 21: 476-83. PMID 15087826 DOI: 10.1097/00024382-200405000-00013  0.299
2009 Phornphutkul C, Lee M, Voigt C, Wu KY, Ehrlich MG, Gruppuso PA, Chen Q. The effect of rapamycin on bone growth in rabbits. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 27: 1157-61. PMID 19382193 DOI: 10.1002/Jor.20894  0.294
2016 Chorzalska AD, Morgan J, Treaba DO, Olszewski AJ, Kingston N, Cheng Y, Lombardo K, Schorl C, Yu X, Zini R, Pacilli A, Tepper A, Hryniewicz-Jankowska A, Zhao T, Oancea E, ... ... Gruppuso P, et al. Bone Marrow-Specific Loss of ABI1 Induces Myelofibrosis through a Mechanism Involving Activation of NFκB Blood. 128: 1203-1203. DOI: 10.1182/Blood.V128.22.1203.1203  0.292
1992 Gruppuso PA, Boylan JM, Levine BA, Ellis L. Insulin receptor tyrosine kinase domain auto-dephosphorylation. Biochemical and Biophysical Research Communications. 189: 1457-63. PMID 1336369 DOI: 10.1016/0006-291X(92)90238-G  0.284
1996 Boney CM, Smith R, Gruppuso PA. 3T3-L1 PREADIPOCYTE (PA) DIFFERENTIATION IS ASSOCIATED WITH LOSS OF INSULIN-LIKE GROWTH FACTOR-1 (IGF-1) ACTIVATION OF MAP KINASES. ▴492 Pediatric Research. 39: 84-84. DOI: 10.1203/00006450-199604001-00512  0.281
1996 Barnum CL, Bovlan JM, Gruppuso PA. Nutritional modulation of hepatic m1togenic signaling in the rat Faseb Journal. 10: A1250.  0.278
2009 Phornphutkul C, Gruppuso PA. Disorders of the growth plate. Current Opinion in Endocrinology, Diabetes, and Obesity. 16: 430-4. PMID 19770649 DOI: 10.1097/Med.0B013E328331Dca2  0.276
2019 Hodax J, Quintos JB, Gruppuso P, Chen Q, Jayasuriya C. MON-262 Aggrecan Is Required for Chondrocyte Differentiation in ATDC5 Chondroprogenitor Cells Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Mon-262  0.273
1993 Aparicio L, Carpenter MW, Schwartz R, Gruppuso PA. Prenatal diagnosis of familial neonatal hyperinsulinemia. Acta Paediatrica (Oslo, Norway : 1992). 82: 683-6. PMID 8374219 DOI: 10.1111/J.1651-2227.1993.Tb18040.X  0.271
1988 Gruppuso PA, Frank BH, Schwartz R. Binding of proinsulin and proinsulin conversion intermediates to human placental insulin-like growth factor I receptors Journal of Clinical Endocrinology and Metabolism. 67: 194-197. PMID 2967852 DOI: 10.1210/Jcem-67-1-194  0.27
1990 Patten JL, Johns DR, Valle D, Eil C, Gruppuso PA, Steele G, Smallwood PM, Levine MA. Mutation in the gene encoding the stimulatory G protein of adenylate cyclase in Albright's hereditary osteodystrophy New England Journal of Medicine. 322: 1412-1419. PMID 2109828 DOI: 10.1056/Nejm199005173222002  0.266
1984 Domenech M, Gruppuso PA, Nishino VT, Susa JB, Schwartz R. A NOVEL MODEL OF MATERNAL HYPOAMINOACIDEMIA Pediatric Research. 18: 137A-137A. DOI: 10.1203/00006450-198404001-00263  0.266
1985 Gruppuso PA, DeLuca F, O'Shea PA, Schwartz R. Near-total pancreatectomy for hyperinsulinism. Spontaneous remission of resultant diabetes Acta Paediatrica Scandinavica. 74: 311-315. PMID 3887837 DOI: 10.1111/J.1651-2227.1985.Tb10974.X  0.256
1987 Gruppuso PA, Susa JB, Sehgal P, Frank B, Schwartz R. Metabolism and placental transfer of 125I-proinsulin and 125I-tyrosylated C-peptide in the pregnant rhesus monkey Journal of Clinical Investigation. 80: 1132-1137. PMID 3654973 DOI: 10.1172/Jci113170  0.252
1989 Gruppuso PA, Schwartz R. Hypoglycemia in children Pediatrics in Review. 11: 117-124. PMID 2678050 DOI: 10.1542/Pir.11-4-117  0.247
1990 Gruppuso PA, Mead JE, Fausto N. Transforming Growth Factor Receptors in Liver Regeneration following Partial Hepatectomy in the Rat Cancer Research. 50: 1464-1469. PMID 2154324  0.246
1998 Phornphutkul C, Boney CM, Gruppuso PA. A novel presentation of Addison disease: hypoglycemia unawareness in an adolescent with insulin-dependent diabetes mellitus. The Journal of Pediatrics. 132: 882-4. PMID 9602207 DOI: 10.1016/S0022-3476(98)70325-7  0.246
1986 Domenech M, Gruppuso PA, Nishino VT, Susa JB, Schwartz R. Preserved fetal plasma amino acid concentrations in the presence of maternal hypoaminoacidemia Pediatric Research. 20: 1071-1076. PMID 3797100 DOI: 10.1203/00006450-198611000-00002  0.245
2002 Gruppuso PA. The clinical laboratory evaluation of GH responsiveness. The Journal of Clinical Endocrinology and Metabolism. 87: 466-8. PMID 11836269 DOI: 10.1210/Jcem.87.2.8312  0.244
2012 Bhutta AQ, Wen S, Boylan JM, Gruppuso P, Moss SF. Su1666 Cag-Dependent Activation of mTOR Signaling by H. pylori Gastroenterology. 142: S-477. DOI: 10.1016/S0016-5085(12)61810-1  0.243
1994 Schwartz R, Gruppuso PA, Petzold K, Brambilla D, Hiilesmaa V, Teramo KA. Hyperinsulinemia and macrosomia in the fetus of the diabetic mother. Diabetes Care. 17: 640-8. PMID 7924772 DOI: 10.2337/Diacare.17.7.640  0.242
1987 Chan SJ, Seino S, Gruppuso PA, Schwartz R, Steiner DF. A mutation in the B chain coding region is associated with impaired proinsulin conversion in a family with hyperproinsulinemia Proceedings of the National Academy of Sciences of the United States of America. 84: 2194-2197. PMID 3470784 DOI: 10.1073/Pnas.84.8.2194  0.241
2001 Phornphutkul C, Okubo T, Wu K, Harel Z, Tracy TF, Pinar H, Chen S, Gruppuso PA, Goodwin G. Aromatase p450 expression in a feminizing adrenal adenoma presenting as isosexual precocious puberty. The Journal of Clinical Endocrinology and Metabolism. 86: 649-52. PMID 11158024 DOI: 10.1210/Jcem.86.2.7201  0.233
1987 Gruppuso PA, Shriner CL, Brautigan DL. Latent forms of type-1 protein phosphatase in rabbit skeletal muscle Biochemical and Biophysical Research Communications. 148: 1174-1181. PMID 2825677 DOI: 10.1016/S0006-291X(87)80256-5  0.232
1987 Gruppuso PA, Susa JB, Sehgal P, Frank B, Schwartz R. METABOLISM OF C-PEPTIDE IN THE PREGNANT RHESUS MONKEY Pediatric Research. 21: 342A-342A. DOI: 10.1203/00006450-198704010-01048  0.229
1988 Carpenter MW, Coustan DR, Widness JA, Gruppuso PA, Malone M, Rotondo LM. Postpartum testing for antecedent gestational diabetes American Journal of Obstetrics and Gynecology. 159: 1128-1131. PMID 3189447 DOI: 10.1016/0002-9378(88)90428-0  0.227
1996 Lesser KB, Gruppuso PA, Terry RB, Carpenter MW. Exercise fails to improve postprandial glycemic excursion in women with gestational diabetes. The Journal of Maternal-Fetal Medicine. 5: 211-7. PMID 8796796 DOI: 10.1002/(Sici)1520-6661(199607/08)5:4<211::Aid-Mfm9>3.0.Co;2-N  0.227
1995 Partyka CM, Gelardi NL, Fadden K, Rifai A, Gruppuso PA, Oh W, Reddy GS. Lack of production and growth-modulating effects of 1a,25-dihydroxyvitamin D3 in cultured fetal rat hepatocytes. Biology of the Neonate. 67: 194-202. PMID 7640319 DOI: 10.1159/000244163  0.224
2011 Pingul MM, Hughes N, Wu A, Stanley CA, Gruppuso PA. Hepatocyte nuclear factor 4α gene mutation associated with familial neonatal hyperinsulinism and maturity-onset diabetes of the young. The Journal of Pediatrics. 158: 852-4. PMID 21353246 DOI: 10.1016/J.Jpeds.2011.01.003  0.224
2003 Sullivan-Bolyai S, Deatrick J, Gruppuso P, Tamborlane W, Grey M. Constant vigilance: Mothers' work parenting young children with type 1 diabetes Journal of Pediatric Nursing. 18: 21-29. PMID 12610784 DOI: 10.1053/Jpdn.2003.4  0.223
1992 Gruppuso PA, Boylan JM. Heterogeneity of hepatic protein tyrosine phosphatases. Second Messengers and Phosphoproteins. 14: 99-108. PMID 1345343  0.222
1998 Lipeski LE, Bausserman LL, Gruppuso PA, Vohr BR. Dyslipidemia in Offspring of Mothers with Gestational Diabetes • 1543 Pediatric Research. 43: 264-264. DOI: 10.1203/00006450-199804001-01565  0.221
2004 Kadmon PM, Gruppuso PA. Glycemic control with metformin or insulin therapy in adolescents with type 2 diabetes mellitus. Journal of Pediatric Endocrinology & Metabolism : Jpem. 17: 1185-93. PMID 15506677 DOI: 10.1515/Jpem.2004.17.9.1185  0.22
1991 Fausto N, Mead JE, Gruppuso PA, Castilla A, Jakowlew SB. Effects of TGF-beta s in the liver: cell proliferation and fibrogenesis Ciba Foundation Symposium. 157: 165-174; discussion . PMID 1649033 DOI: 10.1002/9780470514061.ch11  0.219
2000 Phornphutkul C, Fausto-Sterling A, Gruppuso PA. Gender self-reassignment in an XY adolescent female born with ambiguous genitalia. Pediatrics. 106: 135-7. PMID 10878164 DOI: 10.1542/Peds.106.1.135  0.215
2002 Sullivan-Bolyai S, Deatrick J, Gruppuso P, Tamborlane W, Grey M. Mothers' experiences raising young children with type 1 diabetes. Journal For Specialists in Pediatric Nursing : Jspn. 7: 93-103. PMID 12236249 DOI: 10.1111/J.1744-6155.2002.Tb00158.X  0.212
2010 Boninger M, Troen P, Green E, Borkan J, Lance-Jones C, Humphrey A, Gruppuso P, Kant P, McGee J, Willochell M, Schor N, Kanter SL, Levine AS. Implementation of a longitudinal mentored scholarly project: an approach at two medical schools. Academic Medicine : Journal of the Association of American Medical Colleges. 85: 429-37. PMID 20182115 DOI: 10.1097/Acm.0B013E3181Ccc96F  0.211
2004 Sullivan-Bolyai S, Grey M, Deatrick J, Gruppuso P, Giraitis P, Tamborlane W. Helping other mothers effectively work at raising young children with type 1 diabetes. The Diabetes Educator. 30: 476-84. PMID 15208845 DOI: 10.1177/014572170403000319  0.205
1998 Phornphutkul C, Boney CM, Fausto-Sterling A, Gruppuso PA. Gender Assignment at Birth: Three Cases of Reassignment/Ambiguity At or Beyond Adolesence † 466 Pediatric Research. 43: 82-82. DOI: 10.1203/00006450-199804001-00487  0.204
1993 Hoegsberg B, Gruppuso PA, Coustan DR. Hyperinsulinemia in macrosomic infants of nondiabetic mothers. Diabetes Care. 16: 32-6. PMID 8422801 DOI: 10.2337/Diacare.16.1.32  0.203
2016 Gruppuso PA, Adashi EY. Residency Placement Fever: Is It Time for a Reevaluation? Academic Medicine : Journal of the Association of American Medical Colleges. PMID 27805954 DOI: 10.1097/Acm.0000000000001468  0.203
2018 Adashi EY, Ahmed AH, Gruppuso PA. The Importance of Being Curious. The American Journal of Medicine. PMID 30571933 DOI: 10.1016/J.Amjmed.2018.12.002  0.203
2010 Parsonnet J, Gruppuso PA, Kanter SL, Boninger M. Required vs. elective research and in-depth scholarship programs in the medical student curriculum. Academic Medicine : Journal of the Association of American Medical Colleges. 85: 405-8. PMID 20182112 DOI: 10.1097/Acm.0B013E3181Cccdc4  0.203
2016 DeLuca M, Gruppuso PA, Wing EJ. Successful treatment of Takayasu’s arteritis in a HIV positive adult patient with long term follow up Case Reports in Internal Medicine. 3: 14. DOI: 10.5430/Crim.V3N4P14  0.202
2010 Adashi EY, Gruppuso PA. Commentary: the unsustainable cost of undergraduate medical education: an overlooked element of U.S. health care reform. Academic Medicine : Journal of the Association of American Medical Colleges. 85: 763-5. PMID 20520022 DOI: 10.1097/Acm.0B013E3181D5Cff7  0.2
2010 Green EP, Borkan JM, Pross SH, Adler SR, Nothnagle M, Parsonnet J, Gruppuso PA. Encouraging scholarship: medical school programs to promote student inquiry beyond the traditional medical curriculum. Academic Medicine : Journal of the Association of American Medical Colleges. 85: 409-18. PMID 20182113 DOI: 10.1097/Acm.0B013E3181Cd3E00  0.2
1997 Phornphutkul C, Boney CM, Gruppuso PA. A Novel Presentation of Addison's Disease: Hypoglycemia Unawareness(HU) in an Adolescent with Type I Diabetes Mellitus (IDDM) 411 Pediatric Research. 41: 71-71. DOI: 10.1203/00006450-199704001-00431  0.199
1973 Gruppuso PA, Kinter LB. DDT Inhibition of active chlorophenol red transport in goldfish (Carassius Auratus) renal tubules Bulletin of Environmental Contamination and Toxicology. 10: 181-186. PMID 4753270 DOI: 10.1007/Bf01720701  0.199
2017 Green EP, Gruppuso PA. Justice and care: decision making by medical school student promotions committees. Medical Education. 51: 621-632. PMID 28488300 DOI: 10.1111/Medu.13280  0.198
2001 Kadmon PM, Noto RB, Boney CM, Goodwin G, Gruppuso PA. Thyroid storm in a child following radioactive iodine (RAI) therapy: a consequence of RAI versus withdrawal of antithyroid medication. The Journal of Clinical Endocrinology and Metabolism. 86: 1865-7. PMID 11344172 DOI: 10.1210/Jcem.86.5.7473  0.197
2016 Ahsan N, Rao RS, Gruppuso PA, Ramratnam B, Salomon AR. Targeted proteomics: Current status and future perspectives for quantification of food allergens. Journal of Proteomics. PMID 27113134 DOI: 10.1016/J.Jprot.2016.04.018  0.196
2005 Dreger AD, Chase C, Sousa A, Gruppuso PA, Frader J. Changing the nomenclature/taxonomy for intersex: a scientific and clinical rationale. Journal of Pediatric Endocrinology & Metabolism : Jpem. 18: 729-33. PMID 16200837 DOI: 10.1515/Jpem.2005.18.8.729  0.196
2015 George P, Green EP, Park YS, Gruppuso PA. A 5-year experience with an elective scholarly concentrations program. Medical Education Online. 20: 29278. PMID 26561482 DOI: 10.3402/Meo.V20.29278  0.196
1999 Kadmon P, Phornphutkul C, Goodwin G, Boney CM, Gruppuso PA. Thyroid Storm in a Child Following Radioactive Iodine (RAI) Ablation: A Consequence of RAI Versus Withdrawal of Antithyroid Medication Pediatric Research. 45: 91A-91A. DOI: 10.1203/00006450-199904020-00545  0.195
2015 George P, Park YS, Ip J, Gruppuso PA, Adashi EY. The Association Between Premedical Curricular and Admission Requirements and Medical School Performance and Residency Placement: A Study of Two Admission Routes at the Warren Alpert Medical School of Brown University. Academic Medicine : Journal of the Association of American Medical Colleges. PMID 26422591 DOI: 10.1097/Acm.0000000000000922  0.195
2017 Adashi EY, Krishna GR, Gruppuso PA. For-Profit Medical Schools-A Flexnerian Legacy Upended. Jama. PMID 28241197 DOI: 10.1001/Jama.2017.0920  0.193
1983 Gruppuso PA, O'Shea PA, Orson JM, Brem AS. Juvenile nephronophthisis with blindness in a three-month-old infant. Senior's syndrome associated with relative parathyroid insufficiency Clinical Pediatrics. 22: 114-118. PMID 6822015 DOI: 10.1177/000992288302200205  0.192
2017 Chorzalska A, Flores Kim J, Roder K, Tepper A, Ahsan N, Rao RS, Olszewski AJ, Yu X, Terentyev D, Morgan J, Treaba DO, Zhao T, Liang O, Gruppuso P, Dubielecka P. Long-term exposure to imatinib mesylate downregulates Hippo pathway and activates YAP in a model of chronic myelogenous leukemia. Stem Cells and Development. PMID 28103766 DOI: 10.1089/scd.2016.0262  0.191
2010 Gruppuso PA, Dollase R, Dumenco L, Taylor J, Green E. The Warren Alpert Medical School of Brown University. Academic Medicine : Journal of the Association of American Medical Colleges. 85: S520-4. PMID 20736621 DOI: 10.1097/Acm.0B013E3181Ea67Ef  0.19
2011 Sullivan-Bolyai S, Bova C, Lee M, Gruppuso PA. Mentoring fathers of children newly diagnosed with T1DM. McN. the American Journal of Maternal Child Nursing. 36: 224-31. PMID 21709518 DOI: 10.1097/Nmc.0B013E3182183Bf5  0.19
2010 Sullivan-Bolyai S, Bova C, Leung K, Trudeau A, Lee M, Gruppuso P. Social Support to Empower Parents (STEP): an intervention for parents of young children newly diagnosed with type 1 diabetes. The Diabetes Educator. 36: 88-97. PMID 20016058 DOI: 10.1177/0145721709352384  0.189
2023 Petersen M, Chorzalska A, Pardo M, Rodriguez A, Morgan J, Ahsan N, Zhao T, Liang O, Kotula L, Bertone P, Gruppuso PA, Dubielecka PM. Proximity proteomics reveals role of Abelson interactor 1 in the regulation of TAK1/RIPK1 signaling. Molecular Oncology. PMID 36635880 DOI: 10.1002/1878-0261.13374  0.187
2006 Dreger A, Chase C, Sousa A, Gruppuso PA, Frader J. Re: Houk CP, et al. Intersex classification scheme: a response to the call for a change. J Pediatr Endocrinol Metab 2005; 18: 735-738. Journal of Pediatric Endocrinology & Metabolism : Jpem. 19: 193. PMID 16562596 DOI: 10.1515/Jpem.2006.19.2.193  0.186
1999 Goodwin G, Harel Z, Tracy T, Boney CM, Phornphutkul C, Gruppuso PA. A 7 Year Old Female with Isosexual Precocious Puberty and a Feminizing Adrenal Tumor Pediatric Research. 45: 89A-89A. DOI: 10.1203/00006450-199904020-00532  0.185
2017 Adashi EY, Krishna GR, Gruppuso PA. For-Profit Medical Education-Reply. Jama. 318: 302. PMID 28719690 DOI: 10.1001/Jama.2017.7861  0.182
2019 Li NY, Gruppuso PA, Kalagara S, Eltorai AEM, DePasse JM, Daniels AH. Critical Assessment of the Contemporary Orthopaedic Surgery Residency Application Process. The Journal of Bone and Joint Surgery. American Volume. PMID 31567662 DOI: 10.2106/Jbjs.18.00587  0.18
1991 Gruppuso PA, Mikumo R, Brautigan DL, Braun L. Growth arrest induced by transforming growth factor β1 is accompanied by protein phosphatase activation in human keratinocytes Journal of Biological Chemistry. 266: 3444-3448. PMID 1847373  0.169
2017 Gruppuso PA, Adashi EY. In Reply to Deng et al. Academic Medicine : Journal of the Association of American Medical Colleges. 92: 896. PMID 28654515 DOI: 10.1097/Acm.0000000000001763  0.167
2024 Sheng AY, Gruppuso PA, Suner S, Adashi EY. The 2023 emergency medicine match: Alarming symptom of a health care system in crisis. Aem Education and Training. 8: e10947. PMID 38510732 DOI: 10.1002/aet2.10947  0.12
1986 Brautigan DL, Gruppuso PA, Mumby M. Protein phosphatase type-1 and type-2 catalytic subunits both bind inhibitor-2 and monoclonal immunoglobulins Journal of Biological Chemistry. 261: 14924-14928. PMID 3021755  0.11
1985 Elbein SC, Gruppuso P, Schwartz R, Skolnick M, Permutt MA. Hyperproinsulinemia in a family with a proposed defect in conversion is linked to the insulin gene. Diabetes. 34: 821-4. PMID 2991050 DOI: 10.2337/diab.34.8.821  0.102
2024 Adashi EY, Penzias AS, Gruppuso PA, Kulkarni AD, Zhang Y, Kissin DM, Gutman R. Iatrogenic and Demographic Determinants of the National Plural Birth Increase. Fertility and Sterility. PMID 38246401 DOI: 10.1016/j.fertnstert.2024.01.024  0.09
1984 Gruppuso PA, Gorden P, Kahn CR, Cornblath M, Zeller WP, Schwartz R. Familial hyperproinsulinemia due to a proposed defect in conversion of proinsulin to insulin New England Journal of Medicine. 311: 629-634. PMID 6382002  0.09
2024 Adashi EY, Gruppuso PA, Cohen IG. CRISPR Therapy of Sickle Cell Disease: The Dawning of the Gene Editing Era. The American Journal of Medicine. PMID 38184185 DOI: 10.1016/j.amjmed.2023.12.018  0.088
2021 Fredette ME, Zonfrillo MR, Park S, Quintos JB, Gruppuso PA, Topor LS. Self-reported insulin pump prescribing practices in pediatric type 1 diabetes. Pediatric Diabetes. PMID 33855806 DOI: 10.1111/pedi.13213  0.086
2003 Gruppuso PA. Achieving glycemic control in young children with type 1 diabetes: approaches, pitfalls and new technologies. Medicine and Health, Rhode Island. 86: 107-11. PMID 12751364  0.084
1988 Gruppuso PA, Brautigan DL. Compartmentalized protein phosphorylation/dephosphorylation in glycogen particles from rabbit skeletal muscle Biochemistry International. 16: 1027-1032. PMID 2845990  0.068
2021 Wilson M, Mello MJ, Gruppuso PA. Antibiotics and the Human Microbiome: A Survey of Prescribing Clinicians' Knowledge and Opinions Regarding the Link between Antibiotic-Induced Dysbiosis and Immune-Mediated Disease. Rhode Island Medical Journal (2013). 104: 59-63. PMID 34437668  0.067
2022 Gruppuso PA, Ahmed R, Adashi EY. Valproate Teratogenicity: A Moving Target. Obstetrics and Gynecology. PMID 35926210 DOI: 10.1097/AOG.0000000000004893  0.066
1985 Gruppuso PA, Johnson GL, Constantinides M, Brautigan DL. Phosphorylase phosphatase regulatory subunit. 'Western' blotting with immunoglobulins against inhibitor-2 reveals a protein of M(r) = 60,000 Journal of Biological Chemistry. 260: 4288-4294. PMID 2984199  0.065
2007 Rickards E, Borkan J, Gruppuso PA. Educating the next generation of leaders in medicine: The Scholarly Concentrations Program at the Warren Alpert Medical School of Brown University. Medicine and Health, Rhode Island. 90: 275-6, 280-2. PMID 17970328  0.052
1985 Brautigan DL, Shriner CL, Gruppuso PA. Phosphorylase phosphatase catalytic subunit. Evidence that the M(r) = 33,000 enzyme fragment is derived from a native protein of M(r) = 70,000 Journal of Biological Chemistry. 260: 4295-4302. PMID 2984200  0.049
2020 Adashi EY, Venkatesh KK, Gruppuso PA, Declercq ER. Reducing Maternal Mortality: The Measurement Imperative. Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health. PMID 33279385 DOI: 10.1016/j.whi.2020.10.006  0.049
2015 George P, Tunkel AR, Dollase R, Gruppuso P, Dumenco L, Rapoza B, Borkan J. The Primary Care-Population Medicine Program at The Warren Alpert Medical School of Brown University. Rhode Island Medical Journal (2013). 98: 16-21. PMID 26324970  0.044
2009 Borkan J, Feldmann E, Dollase R, Gruppuso PA. Redesigning the clinical curriculum at the Warren Alpert Medical School of Brown University. Medicine and Health, Rhode Island. 92: 300-2. PMID 19842527  0.041
2021 Morris DB, Gruppuso PA, McGee HA, Murillo AL, Grover A, Adashi EY. Diversity of the National Medical Student Body - Four Decades of Inequities. The New England Journal of Medicine. 384: 1661-1668. PMID 33913645 DOI: 10.1056/NEJMsr2028487  0.039
2015 George P, Green EP, Park YS, Gruppuso PA. A 5-year experience with an elective scholarly concentrations program. Medical Education Online. 20: 29278. PMID 28229676 DOI: 10.3402/meo.v20.29278  0.037
2023 Shachar C, Gruppuso PA, Adashi EY. Pediatric Drug and Other Shortages in the Age of Supply Chain Disruption. Jama. PMID 37294557 DOI: 10.1001/jama.2023.4755  0.035
2006 Embree-Ku M, Gruppuso PA. Does nucleolin bind the NF kappa B DNA binding motif? [6] Hepatology. 43: 376-377. DOI: 10.1002/hep.21057  0.031
2012 Gruppuso PA, Palenchar E, Viticonte J. The Warren Alpert Medical School of Brown University class of 2012. Medicine and Health, Rhode Island. 95: 308-12. PMID 23155848  0.03
2010 Gruppuso PA, Palenchar E, Viticonte J. The Warren Alpert Medical School of Brown University Class of 2010. Medicine and Health, Rhode Island. 93: 228-33. PMID 20827926  0.03
2009 Gruppuso PA, Palenchar E, Viticonte J. The Warren Alpert Medical School of Brown University: Class of 2009. Medicine and Health, Rhode Island. 92: 292-6. PMID 19842525  0.03
2008 Gruppuso PA, Palenchar E, Viticonte J. The Warren Alpert Medical School of Brown University: class of 2008. Medicine and Health, Rhode Island. 91: 242-6. PMID 18754263  0.03
2007 Gruppuso PA, MacConnell J, Viticonte J. The Warren Alpert Medical School of Brown University: Class of 2007. Medicine and Health, Rhode Island. 90: 266-71. PMID 17970326  0.03
2006 Gruppuso PA, Bell R, Viticonte J. The Brown Medical School Class of 2006. Medicine and Health, Rhode Island. 89: 299-303. PMID 17036692  0.028
2007 Garg S, Gruppuso PA, Dumenco L. Redesigning the medical science curriculum at the Warren Alpert Medical School of Brown University. Medicine and Health, Rhode Island. 90: 272-4. PMID 17970327  0.028
2006 Gruppuso PA. Medical education at Brown Medical School. Medicine and Health, Rhode Island. 89: 298. PMID 17036691  0.028
2010 Gruppuso PA, Holden P. A new home for Alpert Medical School. Medicine and Health, Rhode Island. 93: 234-6. PMID 20827927  0.025
2021 Morris DB, Gruppuso PA, Adashi EY. Diversity of the National Medical Student Body. Reply. The New England Journal of Medicine. 385: 479-480. PMID 34320305 DOI: 10.1056/NEJMc2109411#sa3  0.02
2023 Wu JH, Gruppuso PA, Adashi EY. Perverse Incentives: A Challenge for Graduate Medical Education. The American Journal of Medicine. 136: 1141-1142. PMID 37690506 DOI: 10.1016/j.amjmed.2023.08.013  0.02
2021 Wu JH, Gruppuso PA, Adashi EY. The Self-directed Medical Student Curriculum. Jama. 326: 2005-2006. PMID 34724030 DOI: 10.1001/jama.2021.16312  0.02
2021 Adashi EY, Gruppuso PA. The Centers for Medicare and Medicaid Services (CMS) COVID-19 Brief: Unsettling Racial and Ethnic Health Disparities. Journal of the American Board of Family Medicine : Jabfm. 34: S13-S15. PMID 33622810 DOI: 10.3122/jabfm.2021.S1.200450  0.017
2024 Gruppuso PA, Adashi EY, Cohen IG. Options for Building a Diverse Health Care Workforce-Reply. Jama. 331: 358. PMID 38261049 DOI: 10.1001/jama.2023.23400  0.01
2023 Adashi EY, Gruppuso PA, Cohen IG. Affirmative Action Ruled Unconstitutional: Options for Building a Diverse Health Care Workforce. Jama. PMID 37624617 DOI: 10.1001/jama.2023.14886  0.01
2022 Marks PW, Gruppuso PA, Adashi EY. Urgent Need for Next-Generation COVID-19 Vaccines. Jama. PMID 36484995 DOI: 10.1001/jama.2022.22759  0.01
2022 Adashi EY, Gruppuso PA. SARS-CoV-2 Vaccines: The Mucosal Immunity Imperative. Mayo Clinic Proceedings. 97: 1771-1773. PMID 36202490 DOI: 10.1016/j.mayocp.2022.07.002  0.01
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