Amer A. Beg - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
Immunology, Microbiology

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ibrahim ML, Zheng H, Barlow ML, Latif Y, Chen Z, Yu X, Beg AA. Histone Deacetylase Inhibitors Directly Modulate T Cell Gene Expression and Signaling and Promote Development of Effector-Exhausted T Cells in Murine Tumors. Journal of Immunology (Baltimore, Md. : 1950). PMID 38169329 DOI: 10.4049/jimmunol.2300475  0.329
2019 Han T, Jiang S, Zheng H, Yin Q, Xie M, Little MR, Yin X, Chen M, Song SJ, Beg AA, Pandolfi PP, Wan L. Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis. Nature Communications. 10: 3716. PMID 31420536 DOI: 10.1038/S41467-019-11618-7  0.345
2019 Gray JE, Saltos AN, Tanvetyanon T, Haura EB, Creelan BC, Antonia SJ, Shafique M, Zheng H, Dai W, Saller JJ, Chen Z, Tchekmedyian N, Goas K, Thapa R, Boyle TA, ... ... Beg AA, et al. Phase 1/1b study of pembrolizumab plus vorinostat in advanced/metastatic non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31409616 DOI: 10.1158/1078-0432.Ccr-19-1305  0.333
2019 Stewart PA, Welsh EA, Slebos RJC, Fang B, Izumi V, Chambers M, Zhang G, Cen L, Pettersson F, Zhang Y, Chen Z, Cheng CH, Thapa R, Thompson Z, Fellows KM, ... ... Beg AA, et al. Proteogenomic landscape of squamous cell lung cancer. Nature Communications. 10: 3578. PMID 31395880 DOI: 10.1038/S41467-019-11452-X  0.339
2019 Xie M, Zheng H, Madan-Lala R, Dai W, Gimbrone NT, Chen Z, Kinose F, Blackstone SA, Smalley KSM, Cress WD, Haura EB, Rix U, Beg AA. MEK inhibition modulates cytokine response to mediate therapeutic efficacy in lung cancer. Cancer Research. PMID 31362929 DOI: 10.1158/0008-5472.Can-19-0698  0.429
2019 Saltos AN, Tanvetyanon T, Haura EB, Creelan BC, Antonia SJ, Shafique MR, Zheng H, Dai W, Chen Z, Saller JJ, Tchekmedyian N, Goas K, Thapa R, Boyle TA, Chen D, ... Beg AA, et al. Phase I/Ib study of pembrolizumab and vorinostat in patients with metastatic NSCLC (mNSCLC): Updated results. Journal of Clinical Oncology. 37: 9073-9073. DOI: 10.1200/Jco.2019.37.15_Suppl.9073  0.304
2019 Xie M, Zheng H, Madan-Lala R, Dai W, Gimbrone NT, Chen Z, Kinose F, Blackstone SA, Smalley KSM, Cress D, Haura EB, Rix U, Beg AA. Abstract B072: MEK inhibition modulates cytokine response to mediate therapeutic efficacy in lung cancer Molecular Cancer Therapeutics. DOI: 10.1158/1535-7163.Targ-19-B072  0.335
2017 Xie M, Zheng H, Beg A. Abstract 5662: MEK inhibitors potentiate tumor immune surveillance by enhancing cancer cell response of IFNγ Cancer Research. 77: 5662-5662. DOI: 10.1158/1538-7445.Am2017-5662  0.44
2017 Cohen AS, Doligalski ML, Zheng H, Tafreshi NK, Estrella V, Delva N, Nguyen J, Beg A, McLaughlin ML, Morse DL. Abstract 1709: Targeting immune checkpoint therapy to the lung tumor microenvironment Cancer Research. 77: 1709-1709. DOI: 10.1158/1538-7445.Am2017-1709  0.316
2016 Zheng H, Zhao W, Yan C, Watson CC, Messengill M, Xie M, Messengill C, Noyes D, Martinez GV, Afzal R, Chen Z, Ren X, Antonia SJ, Haura EB, Ruffell B, ... Beg AA, et al. HDAC inhibitors enhance T cell chemokine expression and augment response to PD-1 immunotherapy in lung adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26964571 DOI: 10.1158/1078-0432.Ccr-15-2584  0.333
2015 Haura EB, Beg AA, Rix U, Antonia S. Charting Immune Signaling Proteomes En Route to New Therapeutic Strategies. Cancer Immunology Research. 3: 714-20. PMID 26081226 DOI: 10.1158/2326-6066.Cir-15-0094  0.358
2014 Bronk CC, Yoder S, Hopewell EL, Yang S, Celis E, Yu XZ, Beg AA. NF-κB is crucial in proximal T-cell signaling for calcium influx and NFAT activation. European Journal of Immunology. 44: 3741-6. PMID 25251667 DOI: 10.1002/Eji.201444904  0.439
2014 Wang X, Wang J, Zheng H, Xie M, Hopewell EL, Albrecht RA, Nogusa S, García-Sastre A, Balachandran S, Beg AA. Differential requirement for the IKKβ/NF-κB signaling module in regulating TLR- versus RLR-induced type 1 IFN expression in dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 193: 2538-45. PMID 25057006 DOI: 10.4049/Jimmunol.1400675  0.583
2014 Engel BE, Schabath MB, Thompson ZJ, Eschrich SA, Brantley SG, Belock AR, Berglund A, Gray JE, Beg AA, Haura EB, Cress WD. Abstract 4159: Characterization of three recurring STK11/LKB1 mutants in lung adenocarcinoma Cancer Research. 74: 4159-4159. DOI: 10.1158/1538-7445.Am2014-4159  0.329
2013 Beg AA, Khan T, Antonia SJ. A new role for NFκB in immunosurveillance and its implications for cancer immunotherapy. Oncoimmunology. 2: e25963. PMID 24404421 DOI: 10.4161/Onci.25963  0.382
2013 Kim JY, Beg AA, Haura EB. Non-canonical IKKs, IKKϵ and TBK1, as novel therapeutic targets in the treatment of non-small cell lung cancer. Expert Opinion On Therapeutic Targets. 17: 1109-12. PMID 23984985 DOI: 10.1517/14728222.2013.833188  0.327
2013 Haarberg KM, Li J, Heinrichs J, Wang D, Liu C, Bronk CC, Kaosaard K, Owyang AM, Holland S, Masuda E, Tso K, Blazar BR, Anasetti C, Beg AA, Yu XZ. Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice. Blood. 122: 2500-11. PMID 23908466 DOI: 10.1182/Blood-2012-12-471938  0.398
2013 Kim JY, Welsh EA, Oguz U, Fang B, Bai Y, Kinose F, Bronk C, Remsing Rix LL, Beg AA, Rix U, Eschrich SA, Koomen JM, Haura EB. Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 12414-9. PMID 23836654 DOI: 10.1073/Pnas.1220674110  0.375
2013 Yu Y, Wang D, Kaosaard K, Liu C, Fu J, Haarberg K, Anasetti C, Beg AA, Yu XZ. c-Rel is an essential transcription factor for the development of acute graft-versus-host disease in mice. European Journal of Immunology. 43: 2327-37. PMID 23716202 DOI: 10.1002/Eji.201243282  0.39
2013 Hopewell EL, Zhao W, Fulp WJ, Bronk CC, Lopez AS, Massengill M, Antonia S, Celis E, Haura EB, Enkemann SA, Chen DT, Beg AA. Lung tumor NF-κB signaling promotes T cell-mediated immune surveillance. The Journal of Clinical Investigation. 123: 2509-22. PMID 23635779 DOI: 10.1172/Jci67250  0.447
2013 Kim J, Welsh EA, Fang B, Oguz U, Li J, Kinose F, Bronk C, Beg AA, Chen A, Eschrich S, Koomen J, Haura EB. Abstract 937: Dissection of KRAS-driven survival signaling networks via phosphoproteomics in lung cancer cells. Cancer Research. 73: 937-937. DOI: 10.1158/1538-7445.Am2013-937  0.341
2012 Bronk CC, Yu XZ, Beg AA. Targeting PKCθ in alloreactivity and graft-versus-host-disease: unanswered questions and therapeutic potential. Frontiers in Immunology. 3: 259. PMID 22912640 DOI: 10.3389/Fimmu.2012.00259  0.443
2012 Hopewell EL, Bronk CC, Massengill M, Engelman RW, Beg AA. IKKβ-induced inflammation impacts the kinetics but not the magnitude of the immune response to a viral vector. European Journal of Immunology. 42: 681-7. PMID 22161279 DOI: 10.1002/Eji.201141910  0.424
2012 Haarberg KM, Kaosaard K, Li J, Heinrichs J, Bronk C, Owyang AM, Masuda E, Anasetti C, Beg A, Yu X. Genetic and Pharmacologic Inhibition of PKCθ and PKCα Prevents Acute Gvhd While Sparing GVL Activity in Mice. Blood. 120: 3000-3000. DOI: 10.1182/Blood.V120.21.3000.3000  0.412
2011 Balachandran S, Beg AA. Defining emerging roles for NF-κB in antivirus responses: revisiting the interferon-β enhanceosome paradigm. Plos Pathogens. 7: e1002165. PMID 22022260 DOI: 10.1371/Journal.Ppat.1002165  0.452
2011 Ruan Q, Kameswaran V, Zhang Y, Zheng S, Sun J, Wang J, DeVirgiliis J, Liou HC, Beg AA, Chen YH. The Th17 immune response is controlled by the Rel-RORγ-RORγ T transcriptional axis. The Journal of Experimental Medicine. 208: 2321-33. PMID 22006976 DOI: 10.1084/Jem.20110462  0.524
2011 Thapa RJ, Basagoudanavar SH, Nogusa S, Irrinki K, Mallilankaraman K, Slifker MJ, Beg AA, Madesh M, Balachandran S. NF-kappaB protects cells from gamma interferon-induced RIP1-dependent necroptosis. Molecular and Cellular Biology. 31: 2934-46. PMID 21576359 DOI: 10.1128/Mcb.05445-11  0.471
2011 Basagoudanavar SH, Thapa RJ, Nogusa S, Wang J, Beg AA, Balachandran S. Distinct roles for the NF-kappa B RelA subunit during antiviral innate immune responses. Journal of Virology. 85: 2599-610. PMID 21209118 DOI: 10.1128/Jvi.02213-10  0.567
2011 Haarberg KM, Bronk C, Wang D, Beg A, Yu X. Effective Prevention of Acute Graft-Verses-Host Disease by Targeting PKC Alpha and PKC Theta in Mice Blood. 118: 1898-1898. DOI: 10.1182/Blood.V118.21.1898.1898  0.397
2010 Ju J, Naura AS, Errami Y, Zerfaoui M, Kim H, Kim JG, Abd Elmageed ZY, Abdel-Mageed AB, Giardina C, Beg AA, Smulson ME, Boulares AH. Phosphorylation of p50 NF-kappaB at a single serine residue by DNA-dependent protein kinase is critical for VCAM-1 expression upon TNF treatment. The Journal of Biological Chemistry. 285: 41152-60. PMID 20966071 DOI: 10.1074/Jbc.M110.158352  0.381
2010 Wang J, Basagoudanavar SH, Wang X, Hopewell E, Albrecht R, García-Sastre A, Balachandran S, Beg AA. NF-kappa B RelA subunit is crucial for early IFN-beta expression and resistance to RNA virus replication. Journal of Immunology (Baltimore, Md. : 1950). 185: 1720-9. PMID 20610653 DOI: 10.4049/Jimmunol.1000114  0.52
2010 Vang KB, Yang J, Pagán AJ, Li LX, Wang J, Green JM, Beg AA, Farrar MA. Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development. Journal of Immunology (Baltimore, Md. : 1950). 184: 4074-7. PMID 20228198 DOI: 10.4049/Jimmunol.0903933  0.453
2010 Yu X-, Valenzuela JO, Iclozan CA, Blazar BR, Waller EK, Beg AA. PKCθ Is Required For Alloreactivity And GVHD But Not For Immune Responses Toward Leukemia And Infection In Mice Biology of Blood and Marrow Transplantation. 16. DOI: 10.1016/J.Bbmt.2009.12.469  0.308
2009 Yarde DN, Oliveira V, Mathews L, Wang X, Villagra A, Boulware D, Shain KH, Hazlehurst LA, Alsina M, Chen DT, Beg AA, Dalton WS. Targeting the Fanconi anemia/BRCA pathway circumvents drug resistance in multiple myeloma. Cancer Research. 69: 9367-75. PMID 19934314 DOI: 10.1158/0008-5472.Can-09-2616  0.398
2009 Valenzuela JO, Iclozan C, Hossain MS, Prlic M, Hopewell E, Bronk CC, Wang J, Celis E, Engelman RW, Blazar BR, Bevan MJ, Waller EK, Yu XZ, Beg AA. PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice. The Journal of Clinical Investigation. 119: 3774-86. PMID 19907075 DOI: 10.1172/Jci39692  0.546
2009 Wang J, Jacob NK, Ladner KJ, Beg A, Perko JD, Tanner SM, Liyanarachchi S, Fishel R, Guttridge DC. RelA/p65 functions to maintain cellular senescence by regulating genomic stability and DNA repair. Embo Reports. 10: 1272-8. PMID 19779484 DOI: 10.1038/Embor.2009.197  0.376
2009 Plumlee CR, Lee C, Beg AA, Decker T, Shuman HA, Schindler C. Interferons direct an effective innate response to Legionella pneumophila infection. The Journal of Biological Chemistry. 284: 30058-66. PMID 19720834 DOI: 10.1074/Jbc.M109.018283  0.38
2009 Ni HM, Chen X, Shi YH, Liao Y, Beg AA, Fan J, Yin XM. Genetic delineation of the pathways mediated by bid and JNK in tumor necrosis factor-alpha-induced liver injury in adult and embryonic mice. The Journal of Biological Chemistry. 284: 4373-82. PMID 19060338 DOI: 10.1074/Jbc.M807259200  0.344
2009 Yu X, Valenzuela J, Iclozan C, Hossain M, Hopewell E, Bronk C, Wang J, Celis E, Engelman R, Waller EK, Blazar BR, Beg A. Targeting PKCtheta Inhibits Alloreactivity and Graft-Versus-Host Disease While Preserving Graft-Versus-Leukemia and Anti-Infection Activities. Blood. 114: 2458-2458. DOI: 10.1182/Blood.V114.22.2458.2458  0.542
2007 Nefedova Y, Fishman M, Sherman S, Wang X, Beg AA, Gabrilovich DI. Mechanism of all-trans retinoic acid effect on tumor-associated myeloid-derived suppressor cells. Cancer Research. 67: 11021-8. PMID 18006848 DOI: 10.1158/0008-5472.Can-07-2593  0.426
2007 Wang J, Wang X, Hussain S, Zheng Y, Sanjabi S, Ouaaz F, Beg AA. Distinct roles of different NF-kappa B subunits in regulating inflammatory and T cell stimulatory gene expression in dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 6777-88. PMID 17513725 DOI: 10.4049/Jimmunol.178.11.6777  0.66
2007 Wang X, Hussain S, Wang EJ, Wang X, Li MO, García-Sastre A, Beg AA. Lack of essential role of NF-kappa B p50, RelA, and cRel subunits in virus-induced type 1 IFN expression. Journal of Immunology (Baltimore, Md. : 1950). 178: 6770-6. PMID 17513724 DOI: 10.4049/Jimmunol.178.11.6770  0.436
2007 Acharyya S, Villalta SA, Bakkar N, Bupha-Intr T, Janssen PM, Carathers M, Li ZW, Beg AA, Ghosh S, Sahenk Z, Weinstein M, Gardner KL, Rafael-Fortney JA, Karin M, Tidball JG, et al. Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy. The Journal of Clinical Investigation. 117: 889-901. PMID 17380205 DOI: 10.1172/Jci30556  0.361
2007 Chen X, Ding WX, Ni HM, Gao W, Shi YH, Gambotto AA, Fan J, Beg AA, Yin XM. Bid-independent mitochondrial activation in tumor necrosis factor alpha-induced apoptosis and liver injury. Molecular and Cellular Biology. 27: 541-53. PMID 17101783 DOI: 10.1128/Mcb.01166-06  0.33
2007 Oliveira VA, Mathews L, Yarde D, Wang X, Boulware D, Hazlehurst LA, Chen D, Beg A, Dalton WS. NF-kB as a Regulator of FA/BRCA Gene Expression in Multiple Myeloma. Blood. 110: 3508-3508. DOI: 10.1182/Blood.V110.11.3508.3508  0.429
2005 Nefedova Y, Cheng P, Gilkes D, Blaskovich M, Beg AA, Sebti SM, Gabrilovich DI. Activation of dendritic cells via inhibition of Jak2/STAT3 signaling. Journal of Immunology (Baltimore, Md. : 1950). 175: 4338-46. PMID 16177074 DOI: 10.4049/Jimmunol.175.7.4338  0.4
2004 Cavin LG, Venkatraman M, Factor VM, Kaur S, Schroeder I, Mercurio F, Beg AA, Thorgeirsson SS, Arsura M. Regulation of alpha-fetoprotein by nuclear factor-kappaB protects hepatocytes from tumor necrosis factor-alpha cytotoxicity during fetal liver development and hepatic oncogenesis. Cancer Research. 64: 7030-8. PMID 15466196 DOI: 10.1158/0008-5472.Can-04-1647  0.417
2004 Saccani S, Marazzi I, Beg AA, Natoli G. Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response. The Journal of Experimental Medicine. 200: 107-13. PMID 15226358 DOI: 10.1084/Jem.20040196  0.395
2004 Beg AA. ComPPARtmentalizing NF-kappaB in the gut. Nature Immunology. 5: 14-6. PMID 14699401 DOI: 10.1038/Ni0104-14  0.347
2003 Goudeau B, Huetz F, Samson S, Di Santo JP, Cumano A, Beg A, Israël A, Mémet S. IkappaBalpha/IkappaBepsilon deficiency reveals that a critical NF-kappaB dosage is required for lymphocyte survival. Proceedings of the National Academy of Sciences of the United States of America. 100: 15800-5. PMID 14665694 DOI: 10.1073/Pnas.2535880100  0.473
2003 Prendes M, Zheng Y, Beg AA. Regulation of developing B cell survival by RelA-containing NF-kappa B complexes. Journal of Immunology (Baltimore, Md. : 1950). 171: 3963-9. PMID 14530314 DOI: 10.4049/Jimmunol.171.8.3963  0.597
2003 Qu J, Li X, Novitch BG, Zheng Y, Kohn M, Xie JM, Kozinn S, Bronson R, Beg AA, Minden A. PAK4 kinase is essential for embryonic viability and for proper neuronal development. Molecular and Cellular Biology. 23: 7122-33. PMID 14517283 DOI: 10.1128/Mcb.23.20.7122-7133.2003  0.488
2003 Zheng Y, Vig M, Lyons J, Van Parijs L, Beg AA. Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo function. The Journal of Experimental Medicine. 197: 861-74. PMID 12668645 DOI: 10.1084/Jem.20021610  0.618
2002 Tao X, Xu Y, Zheng Y, Beg AA, Tong L. An extensively associated dimer in the structure of the C713S mutant of the TIR domain of human TLR2. Biochemical and Biophysical Research Communications. 299: 216-21. PMID 12437972 DOI: 10.1016/S0006-291X(02)02581-0  0.465
2002 Beg AA. Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses. Trends in Immunology. 23: 509-12. PMID 12401394 DOI: 10.1016/S1471-4906(02)02317-7  0.378
2002 Ouaaz F, Arron J, Zheng Y, Choi Y, Beg AA. Dendritic cell development and survival require distinct NF-kappaB subunits. Immunity. 16: 257-70. PMID 11869686 DOI: 10.1016/S1074-7613(02)00272-8  0.587
2001 Alcamo E, Mizgerd JP, Horwitz BH, Bronson R, Beg AA, Scott M, Doerschuk CM, Hynes RO, Baltimore D. Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-kappa B in leukocyte recruitment. Journal of Immunology (Baltimore, Md. : 1950). 167: 1592-600. PMID 11466381 DOI: 10.4049/Jimmunol.167.3.1592  0.436
2001 Li M, Carpio DF, Zheng Y, Bruzzo P, Singh V, Ouaaz F, Medzhitov RM, Beg AA. An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells. Journal of Immunology (Baltimore, Md. : 1950). 166: 7128-35. PMID 11390458 DOI: 10.4049/Jimmunol.166.12.7128  0.59
2001 Zheng Y, Ouaaz F, Bruzzo P, Singh V, Gerondakis S, Beg AA. NF-kappa B RelA (p65) is essential for TNF-alpha-induced fas expression but dispensable for both TCR-induced expression and activation-induced cell death. Journal of Immunology (Baltimore, Md. : 1950). 166: 4949-57. PMID 11290773 DOI: 10.4049/Jimmunol.166.8.4949  0.625
2001 Li M, Shillinglaw W, Henzel WJ, Beg AA. The Rela(p65) subunit of NF-kappaB is essential for inhibiting double-stranded RNA-induced cytotoxicity. The Journal of Biological Chemistry. 276: 1185-94. PMID 11035014 DOI: 10.1074/Jbc.M006647200  0.425
2000 Wang X, Li M, Zheng H, Muster T, Palese P, Beg AA, García-Sastre A. Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon. Journal of Virology. 74: 11566-73. PMID 11090154 DOI: 10.1128/Jvi.74.24.11566-11573.2000  0.358
2000 Li M, Beg AA. Induction of necrotic-like cell death by tumor necrosis factor alpha and caspase inhibitors: novel mechanism for killing virus-infected cells. Journal of Virology. 74: 7470-7. PMID 10906200 DOI: 10.1128/Jvi.74.16.7470-7477.2000  0.36
2000 Bitzer M, Gersdorff Gv, Liang D, Dominguez-Rosales A, Beg AA, Rojkind M, Böttinger EP. A mechanism of suppression of TGF–β/SMAD signaling by NF-κB/RelA Genes & Development. 14: 187-197. DOI: 10.1101/Gad.14.2.187  0.354
1999 Grossmann M, Metcalf D, Merryfull J, Beg A, Baltimore D, Gerondakis S. The combined absence of the transcription factors Rel and RelA leads to multiple hemopoietic cell defects. Proceedings of the National Academy of Sciences of the United States of America. 96: 11848-53. PMID 10518539 DOI: 10.1073/Pnas.96.21.11848  0.385
1999 Ouaaz F, Li M, Beg AA. A critical role for the RelA subunit of nuclear factor kappaB in regulation of multiple immune-response genes and in Fas-induced cell death. The Journal of Experimental Medicine. 189: 999-1004. PMID 10075983 DOI: 10.1084/Jem.189.6.999  0.473
1997 Finco TS, Westwick JK, Norris JL, Beg AA, Der CJ, Baldwin AS. Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation. The Journal of Biological Chemistry. 272: 24113-6. PMID 9305854 DOI: 10.1074/Jbc.272.39.24113  0.42
1996 Beg AA, Baltimore D. An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science (New York, N.Y.). 274: 782-4. PMID 8864118 DOI: 10.1126/Science.274.5288.782  0.426
1995 Beg AA, Sha WC, Bronson RT, Ghosh S, Baltimore D. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature. 376: 167-70. PMID 7603567 DOI: 10.1038/376167A0  0.429
1995 Beg AA, Sha WC, Bronson RT, Baltimore D. Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice. Genes & Development. 9: 2736-46. PMID 7590249 DOI: 10.1101/Gad.9.22.2736  0.374
1994 Beg AA, Baldwin AS. Activation of multiple NF-kappa B/Rel DNA-binding complexes by tumor necrosis factor. Oncogene. 9: 1487-92. PMID 8152812  0.301
1994 Finco TS, Beg AA, Baldwin AS. Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 91: 11884-8. PMID 7991551 DOI: 10.1073/Pnas.91.25.11884  0.384
1993 Beg AA, Finco TS, Nantermet PV, Baldwin AS. Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation. Molecular and Cellular Biology. 13: 3301-10. PMID 8497253 DOI: 10.1128/mcb.13.6.3301-3310.1993  0.402
1993 Scheinman RI, Beg AA, Baldwin AS. NF-kappa B p100 (Lyt-10) is a component of H2TF1 and can function as an I kappa B-like molecule. Molecular and Cellular Biology. 13: 6089-101. PMID 8413211 DOI: 10.1128/mcb.13.10.6089-6101.1993  0.393
1993 Beg AA, Baldwin AS. The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors. Genes & Development. 7: 2064-70. PMID 8224838 DOI: 10.1101/Gad.7.11.2064  0.354
1992 Beg AA, Ruben SM, Scheinman RI, Haskill S, Rosen CA, Baldwin AS. I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention. Genes & Development. 6: 1899-913. PMID 1340770 DOI: 10.1101/Gad.6.10.1899  0.374
1991 Baldwin AS, Azizkhan JC, Jensen DE, Beg AA, Coodly LR. Induction of NF-kappa B DNA-binding activity during the G0-to-G1 transition in mouse fibroblasts. Molecular and Cellular Biology. 11: 4943-51. PMID 1922027 DOI: 10.1128/mcb.11.10.4943-4951.1991  0.42
1991 Haskill S, Beg AA, Tompkins SM, Morris JS, Yurochko AD, Sampson-Johannes A, Mondal K, Ralph P, Baldwin AS. Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity. Cell. 65: 1281-9. PMID 1829648 DOI: 10.1016/0092-8674(91)90022-Q  0.397
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