Year |
Citation |
Score |
2024 |
Ibrahim ML, Zheng H, Barlow ML, Latif Y, Chen Z, Yu X, Beg AA. Histone Deacetylase Inhibitors Directly Modulate T Cell Gene Expression and Signaling and Promote Development of Effector-Exhausted T Cells in Murine Tumors. Journal of Immunology (Baltimore, Md. : 1950). PMID 38169329 DOI: 10.4049/jimmunol.2300475 |
0.329 |
|
2019 |
Han T, Jiang S, Zheng H, Yin Q, Xie M, Little MR, Yin X, Chen M, Song SJ, Beg AA, Pandolfi PP, Wan L. Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis. Nature Communications. 10: 3716. PMID 31420536 DOI: 10.1038/S41467-019-11618-7 |
0.345 |
|
2019 |
Gray JE, Saltos AN, Tanvetyanon T, Haura EB, Creelan BC, Antonia SJ, Shafique M, Zheng H, Dai W, Saller JJ, Chen Z, Tchekmedyian N, Goas K, Thapa R, Boyle TA, ... ... Beg AA, et al. Phase 1/1b study of pembrolizumab plus vorinostat in advanced/metastatic non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31409616 DOI: 10.1158/1078-0432.Ccr-19-1305 |
0.333 |
|
2019 |
Stewart PA, Welsh EA, Slebos RJC, Fang B, Izumi V, Chambers M, Zhang G, Cen L, Pettersson F, Zhang Y, Chen Z, Cheng CH, Thapa R, Thompson Z, Fellows KM, ... ... Beg AA, et al. Proteogenomic landscape of squamous cell lung cancer. Nature Communications. 10: 3578. PMID 31395880 DOI: 10.1038/S41467-019-11452-X |
0.339 |
|
2019 |
Xie M, Zheng H, Madan-Lala R, Dai W, Gimbrone NT, Chen Z, Kinose F, Blackstone SA, Smalley KSM, Cress WD, Haura EB, Rix U, Beg AA. MEK inhibition modulates cytokine response to mediate therapeutic efficacy in lung cancer. Cancer Research. PMID 31362929 DOI: 10.1158/0008-5472.Can-19-0698 |
0.429 |
|
2019 |
Saltos AN, Tanvetyanon T, Haura EB, Creelan BC, Antonia SJ, Shafique MR, Zheng H, Dai W, Chen Z, Saller JJ, Tchekmedyian N, Goas K, Thapa R, Boyle TA, Chen D, ... Beg AA, et al. Phase I/Ib study of pembrolizumab and vorinostat in patients with metastatic NSCLC (mNSCLC): Updated results. Journal of Clinical Oncology. 37: 9073-9073. DOI: 10.1200/Jco.2019.37.15_Suppl.9073 |
0.304 |
|
2019 |
Xie M, Zheng H, Madan-Lala R, Dai W, Gimbrone NT, Chen Z, Kinose F, Blackstone SA, Smalley KSM, Cress D, Haura EB, Rix U, Beg AA. Abstract B072: MEK inhibition modulates cytokine response to mediate therapeutic efficacy in lung cancer Molecular Cancer Therapeutics. DOI: 10.1158/1535-7163.Targ-19-B072 |
0.335 |
|
2017 |
Xie M, Zheng H, Beg A. Abstract 5662: MEK inhibitors potentiate tumor immune surveillance by enhancing cancer cell response of IFNγ Cancer Research. 77: 5662-5662. DOI: 10.1158/1538-7445.Am2017-5662 |
0.44 |
|
2017 |
Cohen AS, Doligalski ML, Zheng H, Tafreshi NK, Estrella V, Delva N, Nguyen J, Beg A, McLaughlin ML, Morse DL. Abstract 1709: Targeting immune checkpoint therapy to the lung tumor microenvironment Cancer Research. 77: 1709-1709. DOI: 10.1158/1538-7445.Am2017-1709 |
0.316 |
|
2016 |
Zheng H, Zhao W, Yan C, Watson CC, Messengill M, Xie M, Messengill C, Noyes D, Martinez GV, Afzal R, Chen Z, Ren X, Antonia SJ, Haura EB, Ruffell B, ... Beg AA, et al. HDAC inhibitors enhance T cell chemokine expression and augment response to PD-1 immunotherapy in lung adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26964571 DOI: 10.1158/1078-0432.Ccr-15-2584 |
0.333 |
|
2015 |
Haura EB, Beg AA, Rix U, Antonia S. Charting Immune Signaling Proteomes En Route to New Therapeutic Strategies. Cancer Immunology Research. 3: 714-20. PMID 26081226 DOI: 10.1158/2326-6066.Cir-15-0094 |
0.358 |
|
2014 |
Bronk CC, Yoder S, Hopewell EL, Yang S, Celis E, Yu XZ, Beg AA. NF-κB is crucial in proximal T-cell signaling for calcium influx and NFAT activation. European Journal of Immunology. 44: 3741-6. PMID 25251667 DOI: 10.1002/Eji.201444904 |
0.439 |
|
2014 |
Wang X, Wang J, Zheng H, Xie M, Hopewell EL, Albrecht RA, Nogusa S, GarcÃa-Sastre A, Balachandran S, Beg AA. Differential requirement for the IKKβ/NF-κB signaling module in regulating TLR- versus RLR-induced type 1 IFN expression in dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 193: 2538-45. PMID 25057006 DOI: 10.4049/Jimmunol.1400675 |
0.582 |
|
2014 |
Engel BE, Schabath MB, Thompson ZJ, Eschrich SA, Brantley SG, Belock AR, Berglund A, Gray JE, Beg AA, Haura EB, Cress WD. Abstract 4159: Characterization of three recurring STK11/LKB1 mutants in lung adenocarcinoma Cancer Research. 74: 4159-4159. DOI: 10.1158/1538-7445.Am2014-4159 |
0.329 |
|
2013 |
Beg AA, Khan T, Antonia SJ. A new role for NFκB in immunosurveillance and its implications for cancer immunotherapy. Oncoimmunology. 2: e25963. PMID 24404421 DOI: 10.4161/Onci.25963 |
0.382 |
|
2013 |
Kim JY, Beg AA, Haura EB. Non-canonical IKKs, IKKϵ and TBK1, as novel therapeutic targets in the treatment of non-small cell lung cancer. Expert Opinion On Therapeutic Targets. 17: 1109-12. PMID 23984985 DOI: 10.1517/14728222.2013.833188 |
0.327 |
|
2013 |
Haarberg KM, Li J, Heinrichs J, Wang D, Liu C, Bronk CC, Kaosaard K, Owyang AM, Holland S, Masuda E, Tso K, Blazar BR, Anasetti C, Beg AA, Yu XZ. Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice. Blood. 122: 2500-11. PMID 23908466 DOI: 10.1182/Blood-2012-12-471938 |
0.397 |
|
2013 |
Kim JY, Welsh EA, Oguz U, Fang B, Bai Y, Kinose F, Bronk C, Remsing Rix LL, Beg AA, Rix U, Eschrich SA, Koomen JM, Haura EB. Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 12414-9. PMID 23836654 DOI: 10.1073/Pnas.1220674110 |
0.375 |
|
2013 |
Yu Y, Wang D, Kaosaard K, Liu C, Fu J, Haarberg K, Anasetti C, Beg AA, Yu XZ. c-Rel is an essential transcription factor for the development of acute graft-versus-host disease in mice. European Journal of Immunology. 43: 2327-37. PMID 23716202 DOI: 10.1002/Eji.201243282 |
0.39 |
|
2013 |
Hopewell EL, Zhao W, Fulp WJ, Bronk CC, Lopez AS, Massengill M, Antonia S, Celis E, Haura EB, Enkemann SA, Chen DT, Beg AA. Lung tumor NF-κB signaling promotes T cell-mediated immune surveillance. The Journal of Clinical Investigation. 123: 2509-22. PMID 23635779 DOI: 10.1172/Jci67250 |
0.447 |
|
2013 |
Kim J, Welsh EA, Fang B, Oguz U, Li J, Kinose F, Bronk C, Beg AA, Chen A, Eschrich S, Koomen J, Haura EB. Abstract 937: Dissection of KRAS-driven survival signaling networks via phosphoproteomics in lung cancer cells. Cancer Research. 73: 937-937. DOI: 10.1158/1538-7445.Am2013-937 |
0.341 |
|
2012 |
Bronk CC, Yu XZ, Beg AA. Targeting PKCθ in alloreactivity and graft-versus-host-disease: unanswered questions and therapeutic potential. Frontiers in Immunology. 3: 259. PMID 22912640 DOI: 10.3389/Fimmu.2012.00259 |
0.442 |
|
2012 |
Hopewell EL, Bronk CC, Massengill M, Engelman RW, Beg AA. IKKβ-induced inflammation impacts the kinetics but not the magnitude of the immune response to a viral vector. European Journal of Immunology. 42: 681-7. PMID 22161279 DOI: 10.1002/Eji.201141910 |
0.424 |
|
2012 |
Haarberg KM, Kaosaard K, Li J, Heinrichs J, Bronk C, Owyang AM, Masuda E, Anasetti C, Beg A, Yu X. Genetic and Pharmacologic Inhibition of PKCθ and PKCα Prevents Acute Gvhd While Sparing GVL Activity in Mice. Blood. 120: 3000-3000. DOI: 10.1182/Blood.V120.21.3000.3000 |
0.412 |
|
2011 |
Balachandran S, Beg AA. Defining emerging roles for NF-κB in antivirus responses: revisiting the interferon-β enhanceosome paradigm. Plos Pathogens. 7: e1002165. PMID 22022260 DOI: 10.1371/Journal.Ppat.1002165 |
0.452 |
|
2011 |
Ruan Q, Kameswaran V, Zhang Y, Zheng S, Sun J, Wang J, DeVirgiliis J, Liou HC, Beg AA, Chen YH. The Th17 immune response is controlled by the Rel-RORγ-RORγ T transcriptional axis. The Journal of Experimental Medicine. 208: 2321-33. PMID 22006976 DOI: 10.1084/Jem.20110462 |
0.523 |
|
2011 |
Thapa RJ, Basagoudanavar SH, Nogusa S, Irrinki K, Mallilankaraman K, Slifker MJ, Beg AA, Madesh M, Balachandran S. NF-kappaB protects cells from gamma interferon-induced RIP1-dependent necroptosis. Molecular and Cellular Biology. 31: 2934-46. PMID 21576359 DOI: 10.1128/Mcb.05445-11 |
0.471 |
|
2011 |
Basagoudanavar SH, Thapa RJ, Nogusa S, Wang J, Beg AA, Balachandran S. Distinct roles for the NF-kappa B RelA subunit during antiviral innate immune responses. Journal of Virology. 85: 2599-610. PMID 21209118 DOI: 10.1128/Jvi.02213-10 |
0.566 |
|
2011 |
Haarberg KM, Bronk C, Wang D, Beg A, Yu X. Effective Prevention of Acute Graft-Verses-Host Disease by Targeting PKC Alpha and PKC Theta in Mice Blood. 118: 1898-1898. DOI: 10.1182/Blood.V118.21.1898.1898 |
0.397 |
|
2010 |
Ju J, Naura AS, Errami Y, Zerfaoui M, Kim H, Kim JG, Abd Elmageed ZY, Abdel-Mageed AB, Giardina C, Beg AA, Smulson ME, Boulares AH. Phosphorylation of p50 NF-kappaB at a single serine residue by DNA-dependent protein kinase is critical for VCAM-1 expression upon TNF treatment. The Journal of Biological Chemistry. 285: 41152-60. PMID 20966071 DOI: 10.1074/Jbc.M110.158352 |
0.381 |
|
2010 |
Wang J, Basagoudanavar SH, Wang X, Hopewell E, Albrecht R, GarcÃa-Sastre A, Balachandran S, Beg AA. NF-kappa B RelA subunit is crucial for early IFN-beta expression and resistance to RNA virus replication. Journal of Immunology (Baltimore, Md. : 1950). 185: 1720-9. PMID 20610653 DOI: 10.4049/Jimmunol.1000114 |
0.519 |
|
2010 |
Vang KB, Yang J, Pagán AJ, Li LX, Wang J, Green JM, Beg AA, Farrar MA. Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development. Journal of Immunology (Baltimore, Md. : 1950). 184: 4074-7. PMID 20228198 DOI: 10.4049/Jimmunol.0903933 |
0.451 |
|
2010 |
Yu X-, Valenzuela JO, Iclozan CA, Blazar BR, Waller EK, Beg AA. PKCθ Is Required For Alloreactivity And GVHD But Not For Immune Responses Toward Leukemia And Infection In Mice Biology of Blood and Marrow Transplantation. 16. DOI: 10.1016/J.Bbmt.2009.12.469 |
0.307 |
|
2009 |
Yarde DN, Oliveira V, Mathews L, Wang X, Villagra A, Boulware D, Shain KH, Hazlehurst LA, Alsina M, Chen DT, Beg AA, Dalton WS. Targeting the Fanconi anemia/BRCA pathway circumvents drug resistance in multiple myeloma. Cancer Research. 69: 9367-75. PMID 19934314 DOI: 10.1158/0008-5472.Can-09-2616 |
0.398 |
|
2009 |
Valenzuela JO, Iclozan C, Hossain MS, Prlic M, Hopewell E, Bronk CC, Wang J, Celis E, Engelman RW, Blazar BR, Bevan MJ, Waller EK, Yu XZ, Beg AA. PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice. The Journal of Clinical Investigation. 119: 3774-86. PMID 19907075 DOI: 10.1172/Jci39692 |
0.544 |
|
2009 |
Wang J, Jacob NK, Ladner KJ, Beg A, Perko JD, Tanner SM, Liyanarachchi S, Fishel R, Guttridge DC. RelA/p65 functions to maintain cellular senescence by regulating genomic stability and DNA repair. Embo Reports. 10: 1272-8. PMID 19779484 DOI: 10.1038/Embor.2009.197 |
0.375 |
|
2009 |
Plumlee CR, Lee C, Beg AA, Decker T, Shuman HA, Schindler C. Interferons direct an effective innate response to Legionella pneumophila infection. The Journal of Biological Chemistry. 284: 30058-66. PMID 19720834 DOI: 10.1074/Jbc.M109.018283 |
0.38 |
|
2009 |
Ni HM, Chen X, Shi YH, Liao Y, Beg AA, Fan J, Yin XM. Genetic delineation of the pathways mediated by bid and JNK in tumor necrosis factor-alpha-induced liver injury in adult and embryonic mice. The Journal of Biological Chemistry. 284: 4373-82. PMID 19060338 DOI: 10.1074/Jbc.M807259200 |
0.344 |
|
2009 |
Yu X, Valenzuela J, Iclozan C, Hossain M, Hopewell E, Bronk C, Wang J, Celis E, Engelman R, Waller EK, Blazar BR, Beg A. Targeting PKCtheta Inhibits Alloreactivity and Graft-Versus-Host Disease While Preserving Graft-Versus-Leukemia and Anti-Infection Activities. Blood. 114: 2458-2458. DOI: 10.1182/Blood.V114.22.2458.2458 |
0.541 |
|
2007 |
Nefedova Y, Fishman M, Sherman S, Wang X, Beg AA, Gabrilovich DI. Mechanism of all-trans retinoic acid effect on tumor-associated myeloid-derived suppressor cells. Cancer Research. 67: 11021-8. PMID 18006848 DOI: 10.1158/0008-5472.Can-07-2593 |
0.426 |
|
2007 |
Wang J, Wang X, Hussain S, Zheng Y, Sanjabi S, Ouaaz F, Beg AA. Distinct roles of different NF-kappa B subunits in regulating inflammatory and T cell stimulatory gene expression in dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 6777-88. PMID 17513725 DOI: 10.4049/Jimmunol.178.11.6777 |
0.659 |
|
2007 |
Wang X, Hussain S, Wang EJ, Wang X, Li MO, GarcÃa-Sastre A, Beg AA. Lack of essential role of NF-kappa B p50, RelA, and cRel subunits in virus-induced type 1 IFN expression. Journal of Immunology (Baltimore, Md. : 1950). 178: 6770-6. PMID 17513724 DOI: 10.4049/Jimmunol.178.11.6770 |
0.436 |
|
2007 |
Acharyya S, Villalta SA, Bakkar N, Bupha-Intr T, Janssen PM, Carathers M, Li ZW, Beg AA, Ghosh S, Sahenk Z, Weinstein M, Gardner KL, Rafael-Fortney JA, Karin M, Tidball JG, et al. Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy. The Journal of Clinical Investigation. 117: 889-901. PMID 17380205 DOI: 10.1172/Jci30556 |
0.361 |
|
2007 |
Chen X, Ding WX, Ni HM, Gao W, Shi YH, Gambotto AA, Fan J, Beg AA, Yin XM. Bid-independent mitochondrial activation in tumor necrosis factor alpha-induced apoptosis and liver injury. Molecular and Cellular Biology. 27: 541-53. PMID 17101783 DOI: 10.1128/Mcb.01166-06 |
0.33 |
|
2007 |
Oliveira VA, Mathews L, Yarde D, Wang X, Boulware D, Hazlehurst LA, Chen D, Beg A, Dalton WS. NF-kB as a Regulator of FA/BRCA Gene Expression in Multiple Myeloma. Blood. 110: 3508-3508. DOI: 10.1182/Blood.V110.11.3508.3508 |
0.428 |
|
2005 |
Nefedova Y, Cheng P, Gilkes D, Blaskovich M, Beg AA, Sebti SM, Gabrilovich DI. Activation of dendritic cells via inhibition of Jak2/STAT3 signaling. Journal of Immunology (Baltimore, Md. : 1950). 175: 4338-46. PMID 16177074 DOI: 10.4049/Jimmunol.175.7.4338 |
0.4 |
|
2004 |
Cavin LG, Venkatraman M, Factor VM, Kaur S, Schroeder I, Mercurio F, Beg AA, Thorgeirsson SS, Arsura M. Regulation of alpha-fetoprotein by nuclear factor-kappaB protects hepatocytes from tumor necrosis factor-alpha cytotoxicity during fetal liver development and hepatic oncogenesis. Cancer Research. 64: 7030-8. PMID 15466196 DOI: 10.1158/0008-5472.Can-04-1647 |
0.417 |
|
2004 |
Saccani S, Marazzi I, Beg AA, Natoli G. Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response. The Journal of Experimental Medicine. 200: 107-13. PMID 15226358 DOI: 10.1084/Jem.20040196 |
0.395 |
|
2004 |
Beg AA. ComPPARtmentalizing NF-kappaB in the gut. Nature Immunology. 5: 14-6. PMID 14699401 DOI: 10.1038/Ni0104-14 |
0.346 |
|
2003 |
Goudeau B, Huetz F, Samson S, Di Santo JP, Cumano A, Beg A, Israël A, Mémet S. IkappaBalpha/IkappaBepsilon deficiency reveals that a critical NF-kappaB dosage is required for lymphocyte survival. Proceedings of the National Academy of Sciences of the United States of America. 100: 15800-5. PMID 14665694 DOI: 10.1073/Pnas.2535880100 |
0.472 |
|
2003 |
Prendes M, Zheng Y, Beg AA. Regulation of developing B cell survival by RelA-containing NF-kappa B complexes. Journal of Immunology (Baltimore, Md. : 1950). 171: 3963-9. PMID 14530314 DOI: 10.4049/Jimmunol.171.8.3963 |
0.595 |
|
2003 |
Qu J, Li X, Novitch BG, Zheng Y, Kohn M, Xie JM, Kozinn S, Bronson R, Beg AA, Minden A. PAK4 kinase is essential for embryonic viability and for proper neuronal development. Molecular and Cellular Biology. 23: 7122-33. PMID 14517283 DOI: 10.1128/Mcb.23.20.7122-7133.2003 |
0.486 |
|
2003 |
Zheng Y, Vig M, Lyons J, Van Parijs L, Beg AA. Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo function. The Journal of Experimental Medicine. 197: 861-74. PMID 12668645 DOI: 10.1084/Jem.20021610 |
0.616 |
|
2002 |
Tao X, Xu Y, Zheng Y, Beg AA, Tong L. An extensively associated dimer in the structure of the C713S mutant of the TIR domain of human TLR2. Biochemical and Biophysical Research Communications. 299: 216-21. PMID 12437972 DOI: 10.1016/S0006-291X(02)02581-0 |
0.463 |
|
2002 |
Beg AA. Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses. Trends in Immunology. 23: 509-12. PMID 12401394 DOI: 10.1016/S1471-4906(02)02317-7 |
0.378 |
|
2002 |
Ouaaz F, Arron J, Zheng Y, Choi Y, Beg AA. Dendritic cell development and survival require distinct NF-kappaB subunits. Immunity. 16: 257-70. PMID 11869686 DOI: 10.1016/S1074-7613(02)00272-8 |
0.585 |
|
2001 |
Alcamo E, Mizgerd JP, Horwitz BH, Bronson R, Beg AA, Scott M, Doerschuk CM, Hynes RO, Baltimore D. Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-kappa B in leukocyte recruitment. Journal of Immunology (Baltimore, Md. : 1950). 167: 1592-600. PMID 11466381 DOI: 10.4049/Jimmunol.167.3.1592 |
0.436 |
|
2001 |
Li M, Carpio DF, Zheng Y, Bruzzo P, Singh V, Ouaaz F, Medzhitov RM, Beg AA. An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells. Journal of Immunology (Baltimore, Md. : 1950). 166: 7128-35. PMID 11390458 DOI: 10.4049/Jimmunol.166.12.7128 |
0.588 |
|
2001 |
Zheng Y, Ouaaz F, Bruzzo P, Singh V, Gerondakis S, Beg AA. NF-kappa B RelA (p65) is essential for TNF-alpha-induced fas expression but dispensable for both TCR-induced expression and activation-induced cell death. Journal of Immunology (Baltimore, Md. : 1950). 166: 4949-57. PMID 11290773 DOI: 10.4049/Jimmunol.166.8.4949 |
0.624 |
|
2001 |
Li M, Shillinglaw W, Henzel WJ, Beg AA. The Rela(p65) subunit of NF-kappaB is essential for inhibiting double-stranded RNA-induced cytotoxicity. The Journal of Biological Chemistry. 276: 1185-94. PMID 11035014 DOI: 10.1074/Jbc.M006647200 |
0.424 |
|
2000 |
Wang X, Li M, Zheng H, Muster T, Palese P, Beg AA, GarcÃa-Sastre A. Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon. Journal of Virology. 74: 11566-73. PMID 11090154 DOI: 10.1128/Jvi.74.24.11566-11573.2000 |
0.357 |
|
2000 |
Li M, Beg AA. Induction of necrotic-like cell death by tumor necrosis factor alpha and caspase inhibitors: novel mechanism for killing virus-infected cells. Journal of Virology. 74: 7470-7. PMID 10906200 DOI: 10.1128/Jvi.74.16.7470-7477.2000 |
0.359 |
|
2000 |
Bitzer M, Gersdorff Gv, Liang D, Dominguez-Rosales A, Beg AA, Rojkind M, Böttinger EP. A mechanism of suppression of TGF–β/SMAD signaling by NF-κB/RelA Genes & Development. 14: 187-197. DOI: 10.1101/Gad.14.2.187 |
0.353 |
|
1999 |
Grossmann M, Metcalf D, Merryfull J, Beg A, Baltimore D, Gerondakis S. The combined absence of the transcription factors Rel and RelA leads to multiple hemopoietic cell defects. Proceedings of the National Academy of Sciences of the United States of America. 96: 11848-53. PMID 10518539 DOI: 10.1073/Pnas.96.21.11848 |
0.385 |
|
1999 |
Ouaaz F, Li M, Beg AA. A critical role for the RelA subunit of nuclear factor kappaB in regulation of multiple immune-response genes and in Fas-induced cell death. The Journal of Experimental Medicine. 189: 999-1004. PMID 10075983 DOI: 10.1084/Jem.189.6.999 |
0.472 |
|
1997 |
Finco TS, Westwick JK, Norris JL, Beg AA, Der CJ, Baldwin AS. Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation. The Journal of Biological Chemistry. 272: 24113-6. PMID 9305854 DOI: 10.1074/Jbc.272.39.24113 |
0.42 |
|
1996 |
Beg AA, Baltimore D. An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science (New York, N.Y.). 274: 782-4. PMID 8864118 DOI: 10.1126/Science.274.5288.782 |
0.425 |
|
1995 |
Beg AA, Sha WC, Bronson RT, Ghosh S, Baltimore D. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature. 376: 167-70. PMID 7603567 DOI: 10.1038/376167A0 |
0.429 |
|
1995 |
Beg AA, Sha WC, Bronson RT, Baltimore D. Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice. Genes & Development. 9: 2736-46. PMID 7590249 DOI: 10.1101/Gad.9.22.2736 |
0.374 |
|
1994 |
Beg AA, Baldwin AS. Activation of multiple NF-kappa B/Rel DNA-binding complexes by tumor necrosis factor. Oncogene. 9: 1487-92. PMID 8152812 |
0.3 |
|
1994 |
Finco TS, Beg AA, Baldwin AS. Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 91: 11884-8. PMID 7991551 DOI: 10.1073/Pnas.91.25.11884 |
0.384 |
|
1993 |
Beg AA, Finco TS, Nantermet PV, Baldwin AS. Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation. Molecular and Cellular Biology. 13: 3301-10. PMID 8497253 DOI: 10.1128/mcb.13.6.3301-3310.1993 |
0.402 |
|
1993 |
Scheinman RI, Beg AA, Baldwin AS. NF-kappa B p100 (Lyt-10) is a component of H2TF1 and can function as an I kappa B-like molecule. Molecular and Cellular Biology. 13: 6089-101. PMID 8413211 DOI: 10.1128/mcb.13.10.6089-6101.1993 |
0.393 |
|
1993 |
Beg AA, Baldwin AS. The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors. Genes & Development. 7: 2064-70. PMID 8224838 DOI: 10.1101/Gad.7.11.2064 |
0.354 |
|
1992 |
Beg AA, Ruben SM, Scheinman RI, Haskill S, Rosen CA, Baldwin AS. I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention. Genes & Development. 6: 1899-913. PMID 1340770 DOI: 10.1101/Gad.6.10.1899 |
0.374 |
|
1991 |
Baldwin AS, Azizkhan JC, Jensen DE, Beg AA, Coodly LR. Induction of NF-kappa B DNA-binding activity during the G0-to-G1 transition in mouse fibroblasts. Molecular and Cellular Biology. 11: 4943-51. PMID 1922027 DOI: 10.1128/mcb.11.10.4943-4951.1991 |
0.42 |
|
1991 |
Haskill S, Beg AA, Tompkins SM, Morris JS, Yurochko AD, Sampson-Johannes A, Mondal K, Ralph P, Baldwin AS. Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity. Cell. 65: 1281-9. PMID 1829648 DOI: 10.1016/0092-8674(91)90022-Q |
0.396 |
|
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