| Year |
Citation |
Score |
| 2024 |
Kachlany SC, Vega BA. Therapeutic Applications of Leukotoxin. Pathogens (Basel, Switzerland). 13. PMID 38787206 DOI: 10.3390/pathogens13050354 |
0.347 |
|
| 2019 |
Vega BA, Schober LT, Kim T, Belinka BA, Kachlany SC. Aggregatibacter actinomycetemcomitans leukotoxin (LtxA; Leukothera®) requires death receptor Fas, in addition to LFA-1, to trigger cell death in T lymphocytes. Infection and Immunity. PMID 31109948 DOI: 10.1128/Iai.00309-19 |
0.375 |
|
| 2018 |
Nice JB, Balashova NV, Kachlany SC, Koufos E, Krueger E, Lally ET, Brown AC. Leukotoxin Is Delivered to Host Cells in an LFA-1-Indepdendent Manner When Associated with Outer Membrane Vesicles. Toxins. 10. PMID 30322160 DOI: 10.3390/Toxins10100414 |
0.372 |
|
| 2015 |
Kachlany SC. Mechanisms of LtxA (Leukotoxin), a Potent New Anti-Inflammatory Agent for the Treatment of Alopecia Areata. The Journal of Investigative Dermatology. Symposium Proceedings / the Society For Investigative Dermatology, Inc. [and] European Society For Dermatological Research. 17: 19-22. PMID 26551939 DOI: 10.1038/Jidsymp.2015.34 |
0.313 |
|
| 2015 |
DiFranco KM, Johnson-Farley N, Bertino JR, Elson D, Vega BA, Belinka BA, Kachlany SC. LFA-1-targeting Leukotoxin (LtxA; Leukothera®) causes lymphoma tumor regression in a humanized mouse model and requires caspase-8 and Fas to kill malignant lymphocytes. Leukemia Research. 39: 649-56. PMID 25850729 DOI: 10.1016/J.Leukres.2015.03.010 |
0.358 |
|
| 2014 |
Kaur M, Kachlany SC. Aggregatibacter actinomycetemcomitans leukotoxin (LtxA; Leukothera) induces cofilin dephosphorylation and actin depolymerization during killing of malignant monocytes. Microbiology (Reading, England). 160: 2443-52. PMID 25169107 DOI: 10.1099/Mic.0.082347-0 |
0.385 |
|
| 2012 |
DiFranco KM, Gupta A, Galusha LE, Perez J, Nguyen TV, Fineza CD, Kachlany SC. Leukotoxin (Leukothera®) targets active leukocyte function antigen-1 (LFA-1) protein and triggers a lysosomal mediated cell death pathway. The Journal of Biological Chemistry. 287: 17618-27. PMID 22467872 DOI: 10.1074/jbc.M111.314674 |
0.319 |
|
| 2011 |
Bendaoud M, Vinogradov E, Balashova NV, Kadouri DE, Kachlany SC, Kaplan JB. Broad-spectrum biofilm inhibition by Kingella kingae exopolysaccharide. Journal of Bacteriology. 193: 3879-86. PMID 21602333 DOI: 10.1128/Jb.00311-11 |
0.341 |
|
| 2010 |
Forman MS, Nishikubo JB, Han RK, Le A, Balashova NV, Kachlany SC. Gangliosides block Aggregatibacter Actinomycetemcomitans leukotoxin (LtxA)-mediated hemolysis. Toxins. 2: 2824-36. PMID 22069577 DOI: 10.3390/toxins2122824 |
0.324 |
|
| 2010 |
Kachlany SC. Aggregatibacter actinomycetemcomitans leukotoxin: From threat to therapy Journal of Dental Research. 89: 561-570. PMID 20200418 DOI: 10.1177/0022034510363682 |
0.317 |
|
| 2009 |
Balashova NV, Shah C, Patel JK, Megalla S, Kachlany SC. Aggregatibacter actinomycetemcomitans LtxC is required for leukotoxin activity and initial interaction between toxin and host cells. Gene. 443: 42-7. PMID 19450669 DOI: 10.1016/j.gene.2009.05.002 |
0.347 |
|
| 2008 |
Venketaraman V, Lin AK, Le A, Kachlany SC, Connell ND, Kaplan JB. Both leukotoxin and poly-N-acetylglucosamine surface polysaccharide protect Aggregatibacter actinomycetemcomitans cells from macrophage killing. Microbial Pathogenesis. 45: 173-80. PMID 18573331 DOI: 10.1016/J.Micpath.2008.05.007 |
0.377 |
|
| 2006 |
Perez BA, Planet PJ, Kachlany SC, Tomich M, Fine DH, Figurski DH. Genetic analysis of the requirement for flp-2, tadV, and rcpB in Actinobacillus actinomycetemcomitans biofilm formation. Journal of Bacteriology. 188: 6361-75. PMID 16923904 DOI: 10.1128/Jb.00496-06 |
0.421 |
|
| 2006 |
Diaz R, Ghofaily LA, Patel J, Balashova NV, Freitas AC, Labib I, Kachlany SC. Characterization of leukotoxin from a clinical strain of Actinobacillus actinomycetemcomitans. Microbial Pathogenesis. 40: 48-55. PMID 16414241 DOI: 10.1016/j.micpath.2005.10.005 |
0.316 |
|
| 2003 |
Planet PJ, Kachlany SC, Fine DH, DeSalle R, Figurski DH. The Widespread Colonization Island of Actinobacillus actinomycetemcomitans. Nature Genetics. 34: 193-8. PMID 12717435 DOI: 10.1038/Ng1154 |
0.416 |
|
| 2002 |
Kachlany SC, Fine DH, Figurski DH. Purification of secreted leukotoxin (LtxA) from Actinobacillus actinomycetemcomitans. Protein Expression and Purification. 25: 465-71. PMID 12182827 DOI: 10.1016/S1046-5928(02)00037-2 |
0.341 |
|
| 2001 |
Bhattacharjee MK, Kachlany SC, Fine DH, Figurski DH. Nonspecific adherence and fibril biogenesis by Actinobacillus actinomycetemcomitans: TadA protein is an ATPase Journal of Bacteriology. 183: 5927-5936. PMID 11566992 DOI: 10.1128/Jb.183.20.5927-5936.2001 |
0.426 |
|
| 2001 |
Kachlany SC, Planet PJ, DeSalle R, Fine DH, Figurski DH. Genes for tight adherence of Actinobacillus actinomycetemcomitans: from plaque to plague to pond scum. Trends in Microbiology. 9: 429-37. PMID 11553455 DOI: 10.1016/S0966-842X(01)02161-8 |
0.425 |
|
| 2001 |
Kachlany SC, Planet PJ, Desalle R, Fine DH, Figurski DH, Kaplan JB. flp-1, the first representative of a new pilin gene subfamily, is required for non-specific adherence of Actinobacillus actinomycetemcomitans. Molecular Microbiology. 40: 542-54. PMID 11359562 DOI: 10.1046/J.1365-2958.2001.02422.X |
0.467 |
|
| 2000 |
Kachlany SC, Fine DH, Figurski DH. Secretion of RTX leukotoxin by Actinobacillus actinomycetemcomitans Infection and Immunity. 68: 6094-6100. PMID 11035711 DOI: 10.1128/Iai.68.11.6094-6100.2000 |
0.457 |
|
| 2000 |
Kachlany SC, Planet PJ, Bhattacharjee MK, Kollia E, DeSalle R, Fine DH, Figurski DH. Nonspecific adherence by Actinobacillus actinomycetemcomitans requires genes widespread in bacteria and archaea. Journal of Bacteriology. 182: 6169-76. PMID 11029439 DOI: 10.1128/Jb.182.21.6169-6176.2000 |
0.46 |
|
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