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Parameshwaran Ramanan, Ph.D. - Publications

Affiliations: 
2012 Biochemistry, Biophysics, and Molecular Biology Iowa State University, Ames, IA, United States 
Area:
Virology Biology
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Brown CS, Lee MS, Leung DW, Wang T, Xu W, Luthra P, Anantpadma M, Shabman RS, Melito LM, MacMillan KS, Borek DM, Otwinowski Z, Ramanan P, Stubbs AJ, Peterson DS, et al. In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity. Journal of Molecular Biology. 426: 2045-58. PMID 24495995 DOI: 10.1016/J.Jmb.2014.01.010  0.53
2013 Luthra P, Ramanan P, Mire CE, Weisend C, Tsuda Y, Yen B, Liu G, Leung DW, Geisbert TW, Ebihara H, Amarasinghe GK, Basler CF. Mutual antagonism between the ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome Cell Host and Microbe. 14: 74-84. PMID 23870315 DOI: 10.1016/J.Chom.2013.06.010  0.546
2012 Ramanan P, Edwards MR, Shabman RS, Leung DW, Endlich-Frazier AC, Borek DM, Otwinowski Z, Liu G, Huh J, Basler CF, Amarasinghe GK. Structural basis for Marburg virus VP35-mediated immune evasion mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 109: 20661-20666. PMID 23185024 DOI: 10.1073/Pnas.1213559109  0.559
2011 Ramanan P, Shabman RS, Brown CS, Amarasinghe GK, Basler CF, Leung DW. Filoviral immune evasion mechanisms Viruses. 3: 1634-1649. PMID 21994800 DOI: 10.3390/V3091634  0.492
2010 Leung DW, Borek D, Farahbakhsh M, Ramanan P, Nix JC, Wang T, Prins KC, Otwinowski Z, Honzatko RB, Helgeson LA, Basler CF, Amarasinghe GK. Crystallization and preliminary X-ray analysis of Ebola VP35 interferon inhibitory domain mutant proteins Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 66: 689-692. PMID 20516601 DOI: 10.1107/S1744309110013266  0.508
2010 Leung DW, Prins KC, Borek DM, Farahbakhsh M, Tufariello JM, Ramanan P, Nix JC, Helgeson LA, Otwinowski Z, Honzatko RB, Basler CF, Amarasinghe GK. Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35 Nature Structural and Molecular Biology. 17: 165-172. PMID 20081868 DOI: 10.1038/Nsmb.1765  0.532
2010 Prins KC, Delpeut S, Leung DW, Reynard O, Volchkova VA, Reid SP, Ramanan P, Cárdenas WB, Amarasinghe GK, Volchkov VE, Basler CF. Mutations abrogating VP35 interaction with double-stranded RNA render Ebola virus avirulent in guinea pigs Journal of Virology. 84: 3004-3015. PMID 20071589 DOI: 10.1128/Jvi.02459-09  0.559
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