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Frederic Sigoillot, Ph.D. - Publications

Affiliations: 
2005 Wayne State University, Detroit, MI, United States 
Area:
Biochemistry, Cell Biology, Molecular Biology
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12/36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zeng H, Castillo-Cabrera J, Manser M, Lu B, Yang Z, Strande V, Begue D, Zamponi R, Qiu S, Sigoillot F, Wang Q, Lindeman A, Reece-Hoyes JS, Russ C, Bonenfant D, et al. Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC. Elife. 8. PMID 31741433 DOI: 10.7554/Elife.50223  0.406
2018 Leung GP, Feng T, Sigoillot FD, Geyer FC, Shirley MD, Ruddy DA, Rakiec D, Freeman AK, Engelman JA, Jaskelioff M, Stuart DD. Hyperactivation of MAPK Signaling is Deleterious to RAS/RAF Mutant Melanoma. Molecular Cancer Research : McR. PMID 30201825 DOI: 10.1158/1541-7786.Mcr-18-0327  0.344
2014 Sackton KL, Dimova N, Zeng X, Tian W, Zhang M, Sackton TB, Meaders J, Pfaff KL, Sigoillot F, Yu H, Luo X, King RW. Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C. Nature. 514: 646-9. PMID 25156254 DOI: 10.1038/Nature13660  0.374
2013 Lim HJ, Dimova NV, Tan MK, Sigoillot FD, King RW, Shi Y. The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20. Molecular and Cellular Biology. 33: 4166-80. PMID 23979597 DOI: 10.1128/Mcb.00689-13  0.309
2010 Zeng X, Sigoillot F, Gaur S, Choi S, Pfaff KL, Oh DC, Hathaway N, Dimova N, Cuny GD, King RW. Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage. Cancer Cell. 18: 382-95. PMID 20951947 DOI: 10.1016/J.Ccr.2010.08.010  0.4
2007 Sigoillot FD, Kotsis DH, Masko EM, Bame M, Evans DR, Evans HI. Protein kinase C modulates the up-regulation of the pyrimidine biosynthetic complex, CAD, by MAP kinase. Frontiers in Bioscience : a Journal and Virtual Library. 12: 3892-8. PMID 17485345 DOI: 10.2741/2358  0.571
2007 Kotsis DH, Masko EM, Sigoillot FD, Di Gregorio R, Guy-Evans HI, Evans DR. Protein kinase A phosphorylation of the multifunctional protein CAD antagonizes activation by the MAP kinase cascade. Molecular and Cellular Biochemistry. 301: 69-81. PMID 17206380 DOI: 10.1007/S11010-006-9398-X  0.78
2005 Sigoillot FD, Kotsis DH, Serre V, Sigoillot SM, Evans DR, Guy HI. Nuclear localization and mitogen-activated protein kinase phosphorylation of the multifunctional protein CAD. The Journal of Biological Chemistry. 280: 25611-20. PMID 15890648 DOI: 10.1074/Jbc.M504581200  0.76
2004 Sigoillot FD, Sigoillot SM, Guy HI. Breakdown of the regulatory control of pyrimidine biosynthesis in human breast cancer cells. International Journal of Cancer. Journal International Du Cancer. 109: 491-8. PMID 14991569 DOI: 10.1002/ijc.11717  0.681
2003 Sigoillot FD, Berkowski JA, Sigoillot SM, Kotsis DH, Guy HI. Cell cycle-dependent regulation of pyrimidine biosynthesis. The Journal of Biological Chemistry. 278: 3403-9. PMID 12438317 DOI: 10.1074/Jbc.M211078200  0.753
2002 Sigoillot FD, Evans DR, Guy HI. Autophosphorylation of the mammalian multifunctional protein that initiates de novo pyrimidine biosynthesis. The Journal of Biological Chemistry. 277: 24809-17. PMID 11986331 DOI: 10.1074/jbc.M203512200  0.643
2002 Sigoillot FD, Evans DR, Guy HI. Growth-dependent regulation of mammalian pyrimidine biosynthesis by the protein kinase A and MAPK signaling cascades. The Journal of Biological Chemistry. 277: 15745-51. PMID 11872754 DOI: 10.1074/jbc.M201112200  0.662
Low-probability matches (unlikely to be authored by this person)
2022 Paul A, Annunziato S, Lu B, Sun T, Evrova O, Planas-Paz L, Orsini V, Terracciano LM, Charlat O, Loureiro ZY, Ji L, Zamponi R, Sigoillot F, Lei H, Lindeman A, et al. Cell adhesion molecule KIRREL1 is a feedback regulator of Hippo signaling recruiting SAV1 to cell-cell contact sites. Nature Communications. 13: 930. PMID 35177623 DOI: 10.1038/s41467-022-28567-3  0.298
2019 Ji L, Lu B, Zamponi R, Charlat O, Aversa R, Yang Z, Sigoillot F, Zhu X, Hu T, Reece-Hoyes JS, Russ C, Michaud G, Tchorz JS, Jiang X, Cong F. USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin. Nature Communications. 10: 4184. PMID 31519875 DOI: 10.1038/S41467-019-12143-3  0.296
2019 Planas-Paz L, Sun T, Pikiolek M, Cochran NR, Bergling S, Orsini V, Yang Z, Sigoillot F, Jetzer J, Syed M, Neri M, Schuierer S, Morelli L, Hoppe PS, Schwarzer W, et al. YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury. Cell Stem Cell. PMID 31080135 DOI: 10.1016/J.Stem.2019.04.005  0.29
2019 Nolin E, Gans S, Llamas L, Bandyopadhyay S, Brittain SM, Bernasconi-Elias P, Carter KP, Loureiro JJ, Thomas JR, Schirle M, Yang Y, Guo N, Roma G, Schuierer S, Beibel M, ... ... Sigoillot F, et al. Discovery of a ZIP7 inhibitor from a Notch pathway screen. Nature Chemical Biology. PMID 30643281 DOI: 10.1038/S41589-018-0200-7  0.275
2019 Zeng H, Castillo-Cabrera J, Manser M, Lu B, Yang Z, Strande V, Begue D, Zamponi R, Qiu S, Sigoillot F, Wang Q, Lindeman A, Reece-Hoyes JS, Russ C, Bonenfant D, et al. Author response: Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC Elife. DOI: 10.7554/Elife.50223.Sa2  0.268
2016 Riccardi S, Bergling S, Sigoillot F, Beibel M, Werner A, Leighton-Davies J, Knehr J, Bouwmeester T, Parker CN, Roma G, Kinzel B. MiR-210 promotes sensory hair cell formation in the organ of corti. Bmc Genomics. 17: 309. PMID 27121005 DOI: 10.1186/S12864-016-2620-7  0.263
2017 Riba A, Emmenlauer M, Chen A, Sigoillot F, Cong F, Dehio C, Jenkins J, Zavolan M. Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results. Cell Systems. PMID 28215525 DOI: 10.1016/J.Cels.2017.01.011  0.261
2019 Ross NT, Lohmann F, Carbonneau S, Fazal A, Weihofen WA, Gleim S, Salcius M, Sigoillot F, Henault M, Carl SH, Rodríguez-Molina JB, Miller HR, Brittain SM, Murphy J, Zambrowski M, et al. CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma. Nature Chemical Biology. PMID 31819276 DOI: 10.1038/S41589-019-0424-1  0.252
2019 Hyrina A, Jones C, Chen D, Clarkson S, Cochran N, Feucht P, Hoffman G, Lindeman A, Russ C, Sigoillot F, Tsang T, Uehara K, Xie L, Ganem D, Holdorf M. A Genome-wide CRISPR Screen Identifies ZCCHC14 as a Host Factor Required for Hepatitis B Surface Antigen Production. Cell Reports. 29: 2970-2978.e6. PMID 31801065 DOI: 10.1016/J.Celrep.2019.10.113  0.246
2017 Kedves AT, Gleim S, Liang X, Bonal DM, Sigoillot F, Harbinski F, Sanghavi S, Benander C, George E, Gokhale PC, Nguyen QD, Kirschmeier PT, Distel RJ, Jenkins J, Goldberg MS, et al. Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C. The Journal of Clinical Investigation. PMID 29130934 DOI: 10.1172/Jci92914  0.229
2020 Ross NT, Lohmann F, Carbonneau S, Fazal A, Weihofen WA, Gleim S, Salcius M, Sigoillot F, Henault M, Carl SH, Rodríguez-Molina JB, Miller HR, Brittain SM, Murphy J, Zambrowski M, et al. Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma. Nature Chemical Biology. PMID 32139909 DOI: 10.1038/S41589-020-0508-Y  0.222
2014 Yilmazel B, Hu Y, Sigoillot F, Smith JA, Shamu CE, Perrimon N, Mohr SE. Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis. Bmc Bioinformatics. 15: 192. PMID 24934636 DOI: 10.1186/1471-2105-15-192  0.216
2024 Schröder M, Renatus M, Liang X, Meili F, Zoller T, Ferrand S, Gauter F, Li X, Sigoillot F, Gleim S, Stachyra TM, Thomas JR, Begue D, Khoshouei M, Lefeuvre P, et al. DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nature Communications. 15: 275. PMID 38177131 DOI: 10.1038/s41467-023-44237-4  0.206
2021 Wong NM, Frias E, Sigoillot FD, Letendre JH, Hild M, Wong WW. Engineering digitizer circuits for chemical and genetic screens in human cells. Nature Communications. 12: 6150. PMID 34686672 DOI: 10.1038/s41467-021-26359-9  0.194
2019 Hill A, Gleim S, Kiefer F, Sigoillot F, Loureiro J, Jenkins J, Morris MK. Benchmarking network algorithms for contextualizing genes of interest. Plos Computational Biology. 15: e1007403. PMID 31860671 DOI: 10.1371/Journal.Pcbi.1007403  0.179
2021 Cho H, Shen Q, Zhang LH, Okumura M, Kawakami A, Ambrose J, Sigoillot F, Miller HR, Gleim S, Cobos-Correa A, Wang Y, Piechon P, Roma G, Eggimann F, Moore C, et al. CYP27A1-dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism. Cell Chemical Biology. PMID 33794192 DOI: 10.1016/j.chembiol.2021.03.004  0.178
2023 Gurzeler LA, Link M, Ibig Y, Schmidt I, Galuba O, Schoenbett J, Gasser-Didierlaurant C, Parker CN, Mao X, Bitsch F, Schirle M, Couttet P, Sigoillot F, Ziegelmüller J, Uldry AC, et al. Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control. Cell Reports. 42: 113056. PMID 37651229 DOI: 10.1016/j.celrep.2023.113056  0.167
2012 Adamson B, Smogorzewska A, Sigoillot FD, King RW, Elledge SJ. A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response. Nature Cell Biology. 14: 318-28. PMID 22344029 DOI: 10.1038/Ncb2426  0.153
2011 Sigoillot FD, Huckins JF, Li F, Zhou X, Wong ST, King RW. A time-series method for automated measurement of changes in mitotic and interphase duration from time-lapse movies. Plos One. 6: e25511. PMID 21966537 DOI: 10.1371/Journal.Pone.0025511  0.112
2024 Thomas JR, Shelton C, Murphy J, Brittain S, Bray MA, Aspesi P, Concannon J, King FJ, Ihry RJ, Ho DJ, Henault M, Hadjikyriacou A, Neri M, Sigoillot FD, Pham HT, et al. Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical Matter─Compounds with Novel Mechanisms from High-Throughput Screening Profiles. Acs Chemical Biology. PMID 38565185 DOI: 10.1021/acschembio.3c00737  0.088
2022 Li J, Ho DJ, Henault M, Yang C, Neri M, Ge R, Renner S, Mansur L, Lindeman A, Kelly B, Tumkaya T, Ke X, Soler-Llavina G, Shanker G, Russ C, ... ... Sigoillot FD, et al. DRUG-seq Provides Unbiased Biological Activity Readouts for Neuroscience Drug Discovery. Acs Chemical Biology. PMID 35508359 DOI: 10.1021/acschembio.1c00920  0.08
2011 Sigoillot FD, King RW. Vigilance and validation: Keys to success in RNAi screening. Acs Chemical Biology. 6: 47-60. PMID 21142076 DOI: 10.1021/Cb100358F  0.069
2023 Gurzeler LA, Link M, Ibig Y, Schmidt I, Galuba O, Schoenbett J, Gasser-Didierlaurant C, Parker CN, Mao X, Bitsch F, Schirle M, Couttet P, Sigoillot F, Ziegelmüller J, Uldry AC, et al. Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control. Cell Reports. 42: 113159. PMID 37708027 DOI: 10.1016/j.celrep.2023.113159  0.067
2012 Sigoillot FD, Lyman S, Huckins JF, Adamson B, Chung E, Quattrochi B, King RW. A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens. Nature Methods. 9: 363-6. PMID 22343343 DOI: 10.1038/Nmeth.1898  0.057
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