| Year |
Citation |
Score |
| 2024 |
Ewen-Campen B, Joshi N, Hermon AS, Thakkar T, Zirin J, Perrimon N. A collection of split-Gal4 drivers targeting conserved signaling ligands in . Biorxiv : the Preprint Server For Biology. PMID 39416173 DOI: 10.1101/2024.10.10.617664 |
0.81 |
|
| 2024 |
Viswanatha R, Entwisle S, Hu Y, Reap K, Butnaru M, Mohr SE, Perrimon N. Higher resolution pooled genome-wide CRISPR knockout screening in Drosophila cells using integration and anti-CRISPR (IntAC). Biorxiv : the Preprint Server For Biology. PMID 39345359 DOI: 10.1101/2024.09.19.613976 |
0.752 |
|
| 2024 |
Ewen-Campen B, Perrimon N. Wnt signaling modulates the response to DNA damage in the Drosophila wing imaginal disc by regulating the EGFR pathway. Plos Biology. 22: e3002547. PMID 39047051 DOI: 10.1371/journal.pbio.3002547 |
0.721 |
|
| 2024 |
Leung NY, Xu C, Shun Li JS, Ganguly A, Meyerhof GT, Regimbald-Dumas Y, Lane EA, Breault DT, He X, Perrimon N, Montell C. Gut tumors in flies alter the taste valence of an anti-tumorigenic bitter compound. Current Biology : Cb. PMID 39019035 DOI: 10.1016/j.cub.2024.07.021 |
0.431 |
|
| 2024 |
He L, Ahmad M, Wu S, Luo S, Shi W, Guo X, Cao Y, Perrimon N. Dietary Amino Acids Promote Glucagon-like Hormone Release to Generate Novel Calcium Waves in Adipose Tissues. Research Square. PMID 38947048 DOI: 10.21203/rs.3.rs-4493132/v1 |
0.489 |
|
| 2024 |
Leung NY, Xu C, Li JSS, Ganguly A, Meyerhof GT, Regimbald-Dumas Y, Lane EA, Breault DT, He X, Perrimon N, Montell C. Gut tumors in flies alter the taste valence of an anti-tumorigenic bitter compound. Current Biology : Cb. PMID 38823383 DOI: 10.1016/j.cub.2024.04.082 |
0.471 |
|
| 2024 |
Zirin J, Jusiak B, Lopes R, Ewen-Campen B, Bosch JA, Risbeck A, Forman C, Villalta C, Hu Y, Perrimon N. Expanding the toolkit for dual control of gene expression. Elife. 12. PMID 38569007 DOI: 10.7554/eLife.94073 |
0.709 |
|
| 2024 |
Ahmad M, Wu S, Guo X, Perrimon N, He L. Sensing of dietary amino acids and regulation of calcium dynamics in adipose tissues through Adipokinetic hormone in . Biorxiv : the Preprint Server For Biology. PMID 38496667 DOI: 10.1101/2024.03.04.583442 |
0.481 |
|
| 2023 |
Song S, Cho B, Weiner AT, Nissen SB, Ojeda Naharros I, Sanchez Bosch P, Suyama K, Hu Y, He L, Svinkina T, Udeshi ND, Carr SA, Perrimon N, Axelrod JD. Protein phosphatase 1 regulates core PCP signaling. Embo Reports. e56997. PMID 37975164 DOI: 10.15252/embr.202356997 |
0.647 |
|
| 2023 |
Song S, Cho B, Weiner AT, Nissen SB, Naharros IO, Bosch PS, Suyama K, Hu Y, He L, Svinkina T, Udeshi ND, Carr SA, Perrimon N, Axelrod JD. Protein phosphatase 1 regulates core PCP signaling. Biorxiv : the Preprint Server For Biology. PMID 37745534 DOI: 10.1101/2023.09.12.556998 |
0.646 |
|
| 2023 |
Petsakou A, Liu Y, Liu Y, Comjean A, Hu Y, Perrimon N. Cholinergic neurons trigger epithelial Ca currents to heal the gut. Nature. PMID 37722602 DOI: 10.1038/s41586-023-06627-y |
0.778 |
|
| 2023 |
Petsakou A, Liu Y, Liu Y, Comjean A, Hu Y, Perrimon N. Epithelial Ca waves triggered by enteric neurons heal the gut. Biorxiv : the Preprint Server For Biology. PMID 37645990 DOI: 10.1101/2023.08.14.553227 |
0.773 |
|
| 2023 |
Zirin J, Jusiak B, Lopes R, Ewen-Campen B, Bosch J, Villalta C, Forman C, Hu Y, Mohr S, Perrimon N. Expanding the Drosophila toolkit for dual control of gene expression. Biorxiv : the Preprint Server For Biology. PMID 37645802 DOI: 10.1101/2023.08.15.553399 |
0.801 |
|
| 2023 |
Ewen-Campen B, Luan H, Xu J, Singh R, Joshi N, Thakkar T, Berger B, White BH, Perrimon N. split-intein Gal4 provides intersectional genetic labeling that is repressible by Gal80. Proceedings of the National Academy of Sciences of the United States of America. 120: e2304730120. PMID 37276389 DOI: 10.1073/pnas.2304730120 |
0.736 |
|
| 2023 |
Xia B, Viswanatha R, Hu Y, Mohr SE, Perrimon N. Pooled genome-wide CRISPR activation screening for rapamycin resistance genes in cells. Elife. 12. PMID 37078570 DOI: 10.7554/eLife.85542 |
0.753 |
|
| 2023 |
Ewen-Campen B, Luan H, Xu J, Singh R, Joshi N, Thakkar T, Berger B, White BH, Perrimon N. split-intein Gal4 provides intersectional genetic labeling that is fully repressible by Gal80. Biorxiv : the Preprint Server For Biology. PMID 36993523 DOI: 10.1101/2023.03.24.534001 |
0.736 |
|
| 2023 |
He L, Perrimon N. Synthetic Notch receptors and their applications to study cell-cell contacts in vivo. Developmental Cell. 58: 171-173. PMID 36750017 DOI: 10.1016/j.devcel.2023.01.001 |
0.371 |
|
| 2022 |
Kim AR, Xu J, Cheloha R, Mohr SE, Zirin J, Ploegh HL, Perrimon N. NanoTag Nanobody Tools for Drosophila In Vitro and In Vivo Studies. Current Protocols. 2: e628. PMID 36571722 DOI: 10.1002/cpz1.628 |
0.713 |
|
| 2022 |
Hu Y, Ewen-Campen B, Comjean A, Rodiger J, Mohr SE, Perrimon N. Paralog Explorer: A resource for mining information about paralogs in common research organisms. Computational and Structural Biotechnology Journal. 20: 6570-6577. PMID 36467589 DOI: 10.1016/j.csbj.2022.11.041 |
0.72 |
|
| 2022 |
Petsakou A, Perrimon N. Bioelectric regulation of intestinal stem cells. Trends in Cell Biology. PMID 36396487 DOI: 10.1016/j.tcb.2022.10.003 |
0.789 |
|
| 2022 |
Bosch JA, Ugur B, Pichardo-Casas I, Rabasco J, Escobedo F, Zuo Z, Brown B, Celniker S, Sinclair DA, Bellen HJ, Perrimon N. Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in . Elife. 11. PMID 36346220 DOI: 10.7554/eLife.82709 |
0.431 |
|
| 2022 |
Petsakou A, Perrimon N. No sugar, just protein please - says the fly. Nature Metabolism. PMID 36344763 DOI: 10.1038/s42255-022-00665-y |
0.765 |
|
| 2022 |
Xu Y, Viswanatha R, Sitsel O, Roderer D, Zhao H, Ashwood C, Voelcker C, Tian S, Raunser S, Perrimon N, Dong M. CRISPR screens in Drosophila cells identify Vsg as a Tc toxin receptor. Nature. PMID 36171290 DOI: 10.1038/s41586-022-05250-7 |
0.729 |
|
| 2022 |
Dalton HM, Viswanatha R, Brathwaite R, Zuno JS, Berman AR, Rushforth R, Mohr SE, Perrimon N, Chow CY. A genome-wide CRISPR screen identifies DPM1 as a modifier of DPAGT1 deficiency and ER stress. Plos Genetics. 18: e1010430. PMID 36166480 DOI: 10.1371/journal.pgen.1010430 |
0.734 |
|
| 2022 |
Han S, Dias GB, Basting PJ, Viswanatha R, Perrimon N, Bergman CM. Local assembly of long reads enables phylogenomics of transposable elements in a polyploid cell line. Nucleic Acids Research. PMID 36156149 DOI: 10.1093/nar/gkac794 |
0.729 |
|
| 2022 |
Ghosh AC, Hu Y, Tattikota SG, Liu Y, Comjean A, Perrimon N. Modeling exercise using optogenetically contractible Drosophila larvae. Bmc Genomics. 23: 623. PMID 36042416 DOI: 10.1186/s12864-022-08845-6 |
0.767 |
|
| 2022 |
Yang R, Meyer AS, Droujinine IA, Udeshi ND, Hu Y, Guo J, McMahon JA, Carey DK, Xu C, Fang Q, Sha J, Qin S, Rocco D, Wohlschlegel J, Ting AY, ... ... Perrimon N, et al. A genetic model for proximity labelling of the mammalian secretome. Open Biology. 12: 220149. PMID 35946312 DOI: 10.1098/rsob.220149 |
0.782 |
|
| 2022 |
Fell CW, Hagelkruys A, Cicvaric A, Horrer M, Liu L, Li JSS, Stadlmann J, Polyansky AA, Mereiter S, Tejada MA, Kokotović T, Achuta VS, Scaramuzza A, Twyman KA, Morrow MM, ... ... Perrimon N, et al. FIBCD1 is an endocytic GAG receptor associated with a novel neurodevelopmental disorder. Embo Molecular Medicine. e15829. PMID 35916241 DOI: 10.15252/emmm.202215829 |
0.57 |
|
| 2022 |
Kanca O, Zirin J, Hu Y, Tepe B, Dutta D, Lin WW, Ma L, Ge M, Zuo Z, Liu LP, Levis RW, Perrimon N, Bellen HJ. An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR mediated homologous recombination. Elife. 11. PMID 35723254 DOI: 10.7554/eLife.76077 |
0.746 |
|
| 2022 |
Xu J, Liu Y, Li H, Tarashansky AJ, Kalicki CH, Hung RJ, Hu Y, Comjean A, Kolluru SS, Wang B, Quake SR, Luo L, McMahon AP, Dow JAT, Perrimon N. Transcriptional and functional motifs defining renal function revealed by single-nucleus RNA sequencing. Proceedings of the National Academy of Sciences of the United States of America. 119: e2203179119. PMID 35696569 DOI: 10.1073/pnas.2203179119 |
0.362 |
|
| 2022 |
Viswanatha R, Mameli E, Rodiger J, Merckaert P, Feitosa-Suntheimer F, Colpitts TM, Mohr SE, Hu Y, Perrimon N. Author Correction: Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos. Nature Communications. 13: 1813. PMID 35354810 DOI: 10.1038/s41467-022-29489-w |
0.716 |
|
| 2022 |
Li H, Janssens J, De Waegeneer M, Kolluru SS, Davie K, Gardeux V, Saelens W, David FPA, Brbić M, Spanier K, Leskovec J, McLaughlin CN, Xie Q, Jones RC, Brueckner K, ... ... Perrimon N, et al. Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly. Science (New York, N.Y.). 375: eabk2432. PMID 35239393 DOI: 10.1126/science.abk2432 |
0.797 |
|
| 2022 |
Xu J, Kim AR, Cheloha RW, Fischer FA, Li JSS, Feng Y, Stoneburner E, Binari R, Mohr SE, Zirin J, Ploegh HL, Perrimon N. Protein visualization and manipulation in through the use of epitope tags recognized by nanobodies. Elife. 11. PMID 35076390 DOI: 10.7554/eLife.74326 |
0.7 |
|
| 2021 |
Zirin J, Bosch J, Viswanatha R, Mohr SE, Perrimon N. State-of-the-art CRISPR for in vivo and cell-based studies in Drosophila. Trends in Genetics : Tig. PMID 34933779 DOI: 10.1016/j.tig.2021.11.006 |
0.8 |
|
| 2021 |
Viswanatha R, Mameli E, Rodiger J, Merckaert P, Feitosa-Suntheimer F, Colpitts TM, Mohr SE, Hu Y, Perrimon N. Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos. Nature Communications. 12: 6825. PMID 34819517 DOI: 10.1038/s41467-021-27129-3 |
0.745 |
|
| 2021 |
Tattikota SG, Perrimon N. Preparation of Larval Blood Cells for Single-cell RNA Sequencing. Bio-Protocol. 11: e4127. PMID 34541045 DOI: 10.21769/BioProtoc.4127 |
0.762 |
|
| 2021 |
Chatterjee N, Perrimon N. What fuels the fly: Energy metabolism in and its application to the study of obesity and diabetes. Science Advances. 7. PMID 34108216 DOI: 10.1126/sciadv.abg4336 |
0.737 |
|
| 2021 |
Hu Y, Tattikota SG, Liu Y, Comjean A, Gao Y, Forman C, Kim G, Rodiger J, Papatheodorou I, Dos Santos G, Mohr SE, Perrimon N. DRscDB: A single-cell RNA-seq resource for data mining and data comparison across species. Computational and Structural Biotechnology Journal. 19: 2018-2026. PMID 33995899 DOI: 10.1016/j.csbj.2021.04.021 |
0.764 |
|
| 2021 |
Droujinine IA, Meyer AS, Wang D, Udeshi ND, Hu Y, Rocco D, McMahon JA, Yang R, Guo J, Mu L, Carey DK, Svinkina T, Zeng R, Branon T, Tabatabai A, ... ... Perrimon N, et al. Proteomics of protein trafficking by in vivo tissue-specific labeling. Nature Communications. 12: 2382. PMID 33888706 DOI: 10.1038/s41467-021-22599-x |
0.782 |
|
| 2021 |
Mohr SE, Tattikota SG, Xu J, Zirin J, Hu Y, Perrimon N. Methods and tools for spatial mapping of single-cell RNAseq clusters in Drosophila. Genetics. PMID 33713129 DOI: 10.1093/genetics/iyab019 |
0.789 |
|
| 2021 |
Tang HW, Weng JH, Lee WX, Hu Y, Gu L, Cho S, Lee G, Binari R, Li C, Cheng ME, Kim AR, Xu J, Shen Z, Xu C, Asara JM, ... ... Perrimon N, et al. mTORC1-chaperonin CCT signaling regulates mA RNA methylation to suppress autophagy. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33649236 DOI: 10.1073/pnas.2021945118 |
0.32 |
|
| 2021 |
Ghosh AC, Tattikota SG, Liu Y, Comjean A, Hu Y, Barrera V, Ho Sui SJ, Perrimon N. Correction: PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity. Elife. 10. PMID 33475495 DOI: 10.7554/eLife.66685 |
0.775 |
|
| 2020 |
Ghosh AC, Tattikota SG, Liu Y, Comjean A, Hu Y, Barrera V, Ho Sui SJ, Perrimon N. PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity. Elife. 9. PMID 33107824 DOI: 10.7554/eLife.56969 |
0.798 |
|
| 2020 |
Hu Y, Comjean A, Rodiger J, Liu Y, Gao Y, Chung V, Zirin J, Perrimon N, Mohr SE. FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2021 update. Nucleic Acids Research. PMID 33104800 DOI: 10.1093/nar/gkaa936 |
0.697 |
|
| 2020 |
Xia B, Amador G, Viswanatha R, Zirin J, Mohr SE, Perrimon N. CRISPR-based engineering of gene knockout cells by homology-directed insertion in polyploid Drosophila S2R+ cells. Nature Protocols. 15: 3478-3498. PMID 32958931 DOI: 10.1038/S41596-020-0383-8 |
0.808 |
|
| 2020 |
Bosch JA, Chen CL, Perrimon N. Proximity-dependent labeling methods for proteomic profiling in living cells: An update. Wiley Interdisciplinary Reviews. Developmental Biology. e392. PMID 32909689 DOI: 10.1002/wdev.392 |
0.316 |
|
| 2020 |
Ewen-Campen B, Comyn T, Vogt E, Perrimon N. No Evidence that Wnt Ligands Are Required for Planar Cell Polarity in Drosophila. Cell Reports. 32: 108121. PMID 32905771 DOI: 10.1016/J.Celrep.2020.108121 |
0.759 |
|
| 2020 |
Cho B, Yoon SH, Lee D, Koranteng F, Tattikota SG, Cha N, Shin M, Do H, Hu Y, Oh SY, Lee D, Vipin Menon A, Moon SJ, Perrimon N, Nam JW, et al. Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila. Nature Communications. 11: 4483. PMID 32900993 DOI: 10.1038/S41467-020-18135-Y |
0.781 |
|
| 2020 |
Ewen-Campen B, Perrimon N. Expanding the horizons of genome editing in the fruit fly with Cas12a. Proceedings of the National Academy of Sciences of the United States of America. PMID 32883881 DOI: 10.1073/Pnas.2016446117 |
0.734 |
|
| 2020 |
Tattikota SG, Cho B, Liu Y, Hu Y, Barrera V, Steinbaugh MJ, Yoon SH, Comjean A, Li F, Dervis F, Hung RJ, Nam JW, Ho Sui S, Shim J, Perrimon N. A single-cell survey of blood. Elife. 9. PMID 32396065 DOI: 10.7554/Elife.54818 |
0.796 |
|
| 2020 |
Kim K, Lane EA, Saftien A, Wang H, Xu Y, Wirtz-Peitz F, Perrimon N. as a model for studying cystic fibrosis pathophysiology of the gastrointestinal system. Proceedings of the National Academy of Sciences of the United States of America. PMID 32345720 DOI: 10.1073/Pnas.1913127117 |
0.76 |
|
| 2020 |
Zirin J, Hu Y, Liu L, Yang-Zhou D, Colbeth R, Yan D, Ewen-Campen B, Tao R, Vogt E, VanNest S, Cavers C, Villalta C, Comjean A, Sun J, Wang X, ... ... Perrimon N, et al. Large-Scale Transgenic Resource Collections for Loss- and Gain-of-Function Studies. Genetics. PMID 32071193 DOI: 10.1534/Genetics.119.302964 |
0.802 |
|
| 2020 |
Hung RJ, Hu Y, Kirchner R, Liu Y, Xu C, Comjean A, Tattikota SG, Li F, Song W, Ho Sui S, Perrimon N. A cell atlas of the adult midgut. Proceedings of the National Academy of Sciences of the United States of America. PMID 31915294 DOI: 10.1073/pnas.1916820117 |
0.792 |
|
| 2020 |
Bosch JA, Knight S, Kanca O, Zirin J, Yang-Zhou D, Hu Y, Rodiger J, Amador G, Bellen HJ, Perrimon N, Mohr SE. Use of the CRISPR-Cas9 System in Drosophila Cultured Cells to Introduce Fluorescent Tags into Endogenous Genes. Current Protocols in Molecular Biology. 130: e112. PMID 31869524 DOI: 10.1002/cpmb.112 |
0.748 |
|
| 2019 |
Xu C, Franklin B, Tang HW, Regimbald-Dumas Y, Hu Y, Ramos J, Bosch JA, Villalta C, He X, Perrimon N. An in vivo RNAi screen uncovers the role of AdoR signaling and adenosine deaminase in controlling intestinal stem cell activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31852821 DOI: 10.1073/pnas.1900103117 |
0.412 |
|
| 2019 |
Kwon YV, Zhao B, Xu C, Lee J, Chen CL, Vinayagam A, Edgar BA, Perrimon N. The role of translationally controlled tumor protein in proliferation of intestinal stem cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31843907 DOI: 10.1073/pnas.1910850116 |
0.498 |
|
| 2019 |
Chen CL, Rodiger J, Chung V, Viswanatha R, Mohr SE, Hu Y, Perrimon N. SNP-CRISPR: A Web Tool for SNP-Specific Genome Editing. G3 (Bethesda, Md.). PMID 31822517 DOI: 10.1534/G3.119.400904 |
0.722 |
|
| 2019 |
Amamoto R, Garcia MD, West ER, Choi J, Lapan SW, Lane EA, Perrimon N, Cepko CL. Probe-Seq enables transcriptional profiling of specific cell types from heterogeneous tissue by RNA-based isolation. Elife. 8. PMID 31815670 DOI: 10.7554/eLife.51452 |
0.341 |
|
| 2019 |
Bult CJ, Blake JA, Calvi BR, Cherry JM, DiFrancesco V, Fullem R, Howe KL, Kaufman T, Mungall C, Perrimon N, Shimoyama M, Sternberg PW, Thomas P, Westerfield M. The Alliance of Genome Resources: Building a Modern Data Ecosystem for Model Organism Databases. Genetics. 213: 1189. PMID 31796553 DOI: 10.1534/Genetics.119.302523 |
0.306 |
|
| 2019 |
Viswanatha R, Brathwaite R, Hu Y, Li Z, Rodiger J, Merckaert P, Chung V, Mohr SE, Perrimon N. Pooled CRISPR Screens in Drosophila Cells. Current Protocols in Molecular Biology. 129: e111. PMID 31763777 DOI: 10.1002/cpmb.111 |
0.736 |
|
| 2019 |
Bosch JA, Colbeth R, Zirin J, Perrimon N. Gene Knock-Ins in Using Homology-Independent Insertion of Universal Donor Plasmids. Genetics. PMID 31685521 DOI: 10.1534/Genetics.119.302819 |
0.741 |
|
| 2019 |
Kanca O, Zirin J, Garcia-Marques J, Knight SM, Yang-Zhou D, Amador G, Chung H, Zuo Z, Ma L, He Y, Lin WW, Fang Y, Ge M, Yamamoto S, Schulze KL, ... ... Perrimon N, et al. An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms. Elife. 8. PMID 31674908 DOI: 10.7554/Elife.51539 |
0.782 |
|
| 2019 |
Mohr SE, Perrimon N. : a simple system for understanding complexity. Disease Models & Mechanisms. 12. PMID 31562251 DOI: 10.1242/dmm.041871 |
0.322 |
|
| 2019 |
Parkhitko AA, Jouandin P, Mohr SE, Perrimon N. Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species. Aging Cell. e13034. PMID 31460700 DOI: 10.1111/acel.13034 |
0.308 |
|
| 2019 |
Droujinine IA, Perrimon N. The Multidimensional Organization of Interorgan Communication Networks. Developmental Cell. 50: 395-396. PMID 31430450 DOI: 10.1016/j.devcel.2019.07.029 |
0.78 |
|
| 2019 |
Silver JT, Wirtz-Peitz F, Simões S, Pellikka M, Yan D, Binari R, Nishimura T, Li Y, Harris TJC, Perrimon N, Tepass U. Apical polarity proteins recruit the RhoGEF Cysts to promote junctional myosin assembly. The Journal of Cell Biology. PMID 31409654 DOI: 10.1083/Jcb.201807106 |
0.789 |
|
| 2019 |
Ahmad M, He L, Perrimon N. Regulation of insulin and adipokinetic hormone/glucagon production in flies. Wiley Interdisciplinary Reviews. Developmental Biology. e360. PMID 31379062 DOI: 10.1002/wdev.360 |
0.536 |
|
| 2019 |
Zirin J, Ni X, Sack LM, Yang-Zhou D, Hu Y, Brathwaite R, Bulyk ML, Elledge SJ, Perrimon N. Interspecies analysis of MYC targets identifies tRNA synthetases as mediators of growth and survival in MYC-overexpressing cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31262815 DOI: 10.1073/Pnas.1821863116 |
0.732 |
|
| 2019 |
He L, Binari R, Huang J, Falo-Sanjuan J, Perrimon N. study of gene expression with an enhanced dual-color fluorescent transcriptional timer. Elife. 8. PMID 31140975 DOI: 10.7554/eLife.46181 |
0.443 |
|
| 2019 |
Dumesic PA, Egan DF, Gut P, Tran MT, Parisi A, Chatterjee N, Jedrychowski M, Paschini M, Kazak L, Wilensky SE, Dou F, Bogoslavski D, Cartier JA, Perrimon N, Kajimura S, et al. An Evolutionarily Conserved uORF Regulates PGC1α and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna. Cell Metabolism. PMID 31105043 DOI: 10.1016/J.Cmet.2019.04.013 |
0.746 |
|
| 2019 |
Hunter GL, He L, Perrimon N, Charras G, Giniger E, Baum B. A role for actomyosin contractility in Notch signaling. Bmc Biology. 17: 12. PMID 30744634 DOI: 10.1186/S12915-019-0625-9 |
0.47 |
|
| 2019 |
Xu C, Tang HW, Hung RJ, Hu Y, Ni X, Housden BE, Perrimon N. The Septate Junction Protein Tsp2A Restricts Intestinal Stem Cell Activity via Endocytic Regulation of aPKC and Hippo Signaling. Cell Reports. 26: 670-688.e6. PMID 30650359 DOI: 10.1016/j.celrep.2018.12.079 |
0.395 |
|
| 2019 |
Kanca O, Zirin J, Garcia-Marques J, Knight SM, Yang-Zhou D, Amador G, Chung H, Zuo Z, Ma L, He Y, Lin W, Fang Y, Ge M, Yamamoto S, Schulze KL, ... ... Perrimon N, et al. Author response: An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms Elife. DOI: 10.7554/Elife.51539.024 |
0.723 |
|
| 2019 |
Nicholson H, Housden B, Perrimon N, Kaelin WG. Abstract C124: HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-C124 |
0.366 |
|
| 2018 |
Xu C, Ericsson M, Perrimon N. Understanding cellular signaling and systems biology with precision: A perspective from ultrastructure and organelle studies in the midgut. Current Opinion in Systems Biology. 11: 24-31. PMID 31595264 DOI: 10.1016/j.coisb.2018.07.003 |
0.383 |
|
| 2018 |
He L, Ahmad M, Perrimon N. Mechanosensitive channels and their functions in stem cell differentiation. Experimental Cell Research. PMID 30500393 DOI: 10.1016/j.yexcr.2018.11.016 |
0.566 |
|
| 2018 |
Parasram K, Bernardon N, Hammoud M, Chang H, He L, Perrimon N, Karpowicz P. Intestinal Stem Cells Exhibit Conditional Circadian Clock Function. Stem Cell Reports. 11: 1287-1301. PMID 30428387 DOI: 10.1016/J.Stemcr.2018.10.010 |
0.793 |
|
| 2018 |
Doupé DP, Marshall OJ, Dayton H, Brand AH, Perrimon N. intestinal stem and progenitor cells are major sources and regulators of homeostatic niche signals. Proceedings of the National Academy of Sciences of the United States of America. PMID 30404917 DOI: 10.1073/Pnas.1719169115 |
0.586 |
|
| 2018 |
Hu Y, Sopko R, Chung V, Foos M, Studer RA, Landry SD, Liu D, Rabinow L, Gnad F, Beltrao P, Perrimon N. iProteinDB: An Integrative Database of Post-translational Modifications. G3 (Bethesda, Md.). PMID 30397019 DOI: 10.1534/G3.118.200637 |
0.33 |
|
| 2018 |
Okamoto N, Viswanatha R, Bittar R, Li Z, Haga-Yamanaka S, Perrimon N, Yamanaka N. A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila. Developmental Cell. PMID 30293839 DOI: 10.1016/J.Devcel.2018.09.012 |
0.754 |
|
| 2018 |
Song W, Ghosh AC, Cheng D, Perrimon N. Endocrine Regulation of Energy Balance by Drosophila TGF-β/Activins. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 30264417 DOI: 10.1002/Bies.201800044 |
0.565 |
|
| 2018 |
Branon TC, Bosch JA, Sanchez AD, Udeshi ND, Svinkina T, Carr SA, Feldman JL, Perrimon N, Ting AY. Efficient proximity labeling in living cells and organisms with TurboID. Nature Biotechnology. PMID 30125270 DOI: 10.1038/Nbt.4201 |
0.357 |
|
| 2018 |
Viswanatha R, Li Z, Hu Y, Perrimon N. Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in cells. Elife. 7. PMID 30051818 DOI: 10.7554/Elife.36333 |
0.766 |
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| 2018 |
Ewen-Campen B, Perrimon N. Co-selection: A Method for Enriching CRISPR/Cas9-Edited Alleles in . G3 (Bethesda, Md.). PMID 29934375 DOI: 10.1534/G3.118.200498 |
0.718 |
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| 2018 |
Jia Y, Xu RG, Ren X, Ewen-Campen B, Rajakumar R, Zirin J, Yang-Zhou D, Zhu R, Wang F, Mao D, Peng P, Qiao HH, Wang X, Liu LP, Xu B, ... ... Perrimon N, et al. Next-generation CRISPR/Cas9 transcriptional activation in using flySAM. Proceedings of the National Academy of Sciences of the United States of America. PMID 29666231 DOI: 10.1073/Pnas.1800677115 |
0.79 |
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| 2018 |
Tang HW, Hu Y, Chen CL, Xia B, Zirin J, Yuan M, Asara JM, Rabinow L, Perrimon N. The TORC1-Regulated CPA Complex Rewires an RNA Processing Network to Drive Autophagy and Metabolic Reprogramming. Cell Metabolism. PMID 29606597 DOI: 10.1016/J.Cmet.2018.02.023 |
0.707 |
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| 2018 |
Zhang T, Song W, Li Z, Qian W, Wei L, Yang Y, Wang W, Zhou X, Meng M, Peng J, Xia Q, Perrimon N, Cheng D. Krüppel homolog 1 represses insect ecdysone biosynthesis by directly inhibiting the transcription of steroidogenic enzymes. Proceedings of the National Academy of Sciences of the United States of America. PMID 29567866 DOI: 10.1073/pnas.1800435115 |
0.318 |
|
| 2018 |
Lee PT, Zirin J, Kanca O, Lin WW, Schulze KL, Li-Kroeger D, Tao R, Devereaux C, Hu Y, Chung V, Fang Y, He Y, Pan H, Ge M, Zuo Z, ... ... Perrimon N, et al. A gene-specificlibrary for. Elife. 7. PMID 29565247 DOI: 10.7554/Elife.35574 |
0.807 |
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| 2018 |
Guo J, Tang HW, Li J, Perrimon N, Yan D. Xio is a component of thesex determination pathway and RNA-methyladenosine methyltransferase complex. Proceedings of the National Academy of Sciences of the United States of America. PMID 29555755 DOI: 10.1073/Pnas.1720945115 |
0.596 |
|
| 2018 |
He L, Si G, Huang J, Samuel ADT, Perrimon N. Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel. Nature. PMID 29414942 DOI: 10.1038/Nature25744 |
0.473 |
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| 2018 |
Viswanatha R, Li Z, Hu Y, Perrimon N. Author response: Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in Drosophila cells Elife. DOI: 10.7554/Elife.36333.036 |
0.759 |
|
| 2018 |
Lee P, Zirin J, Kanca O, Lin W, Schulze KL, Li-Kroeger D, Tao R, Devereaux C, Hu Y, Chung V, Fang Y, He Y, Pan H, Ge M, Zuo Z, ... ... Perrimon N, et al. Author response: A gene-specific T2A-GAL4 library for Drosophila Elife. DOI: 10.7554/Elife.35574.023 |
0.751 |
|
| 2017 |
Mohr SE, Rudd K, Hu Y, Song WR, Gilly Q, Buckner M, Housden BE, Kelley C, Zirin J, Tao R, Amador G, Sierzputowska K, Comjean A, Perrimon N. Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila melanogaster Cultured Cells. G3 (Bethesda, Md.). PMID 29223976 DOI: 10.1534/G3.117.300447 |
0.724 |
|
| 2017 |
Housden BE, Li Z, Kelley C, Wang Y, Hu Y, Valvezan AJ, Manning BD, Perrimon N. Improved detection of synthetic lethal interactions in Drosophila cells using variable dose analysis (VDA). Proceedings of the National Academy of Sciences of the United States of America. 114: E10755-E10762. PMID 29183982 DOI: 10.1073/Pnas.1713362114 |
0.306 |
|
| 2017 |
Hu Y, Vinayagam A, Nand A, Comjean A, Chung V, Hao T, Mohr SE, Perrimon N. Molecular Interaction Search Tool (MIST): an integrated resource for mining gene and protein interaction data. Nucleic Acids Research. PMID 29155944 DOI: 10.1093/nar/gkx1116 |
0.303 |
|
| 2017 |
Valvezan AJ, Turner M, Belaid A, Lam HC, Miller SK, McNamara MC, Baglini C, Housden BE, Perrimon N, Kwiatkowski DJ, Asara JM, Henske EP, Manning BD. mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability. Cancer Cell. PMID 29056426 DOI: 10.1016/J.Ccell.2017.09.013 |
0.302 |
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| 2017 |
Rajan A, Housden BE, Wirtz-Peitz F, Holderbaum L, Perrimon N. A Mechanism Coupling Systemic Energy Sensing to Adipokine Secretion. Developmental Cell. 43: 83-98.e6. PMID 29017032 DOI: 10.1016/J.Devcel.2017.09.007 |
0.782 |
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| 2017 |
Ewen-Campen B, Mohr SE, Hu Y, Perrimon N. Accessing the Phenotype Gap: Enabling Systematic Investigation of Paralog Functional Complexity with CRISPR. Developmental Cell. 43: 6-9. PMID 29017030 DOI: 10.1016/J.Devcel.2017.09.020 |
0.727 |
|
| 2017 |
Ewen-Campen B, Yang-Zhou D, Fernandes VR, González DP, Liu LP, Tao R, Ren X, Sun J, Hu Y, Zirin J, Mohr SE, Ni JQ, Perrimon N. Optimized strategy for in vivo Cas9-activation in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. PMID 28808002 DOI: 10.1073/Pnas.1707635114 |
0.807 |
|
| 2017 |
Song W, Owusu-Ansah E, Hu Y, Cheng D, Ni X, Zirin J, Perrimon N. Activin signaling mediates muscle-to-adipose communication in a mitochondria dysfunction-associated obesity model. Proceedings of the National Academy of Sciences of the United States of America. PMID 28739899 DOI: 10.1073/Pnas.1708037114 |
0.775 |
|
| 2017 |
Lee HJ, Jedrychowski MP, Vinayagam A, Wu N, Shyh-Chang N, Hu Y, Min-Wen C, Moore JK, Asara JM, Lyssiotis CA, Perrimon N, Gygi SP, Cantley LC, Kirschner MW. Proteomic and Metabolomic Characterization of a Mammalian Cellular Transition from Quiescence to Proliferation. Cell Reports. 20: 721-736. PMID 28723573 DOI: 10.1016/J.Celrep.2017.06.074 |
0.315 |
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| 2017 |
Hu Y, Comjean A, Mohr SE, FlyBase Consortium T, Perrimon N. Gene2Function: An Integrated Online Resource for Gene Function Discovery. G3 (Bethesda, Md.). PMID 28663344 DOI: 10.1534/g3.117.043885 |
0.303 |
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| 2017 |
Teleman AA, Perrimon N. Open questions: completing the parts list and finding the integrating signals. Bmc Biology. 15: 47. PMID 28595578 DOI: 10.1186/s12915-017-0388-0 |
0.34 |
|
| 2017 |
Xu C, Luo J, He L, Montell C, Perrimon N. Oxidative stress induces stem cell proliferation via TRPA1/RyR-mediated Ca(2+) signaling in the Drosophila midgut. Elife. 6. PMID 28561738 DOI: 10.7554/Elife.22441 |
0.622 |
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| 2017 |
Wang J, Al-Ouran R, Hu Y, Kim SY, Wan YW, Wangler MF, Yamamoto S, Chao HT, Comjean A, Mohr SE, Perrimon N, Liu Z, Bellen HJ. MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome. American Journal of Human Genetics. PMID 28502612 DOI: 10.1016/J.Ajhg.2017.04.010 |
0.522 |
|
| 2017 |
He L, Huang J, Perrimon N. Development of an optimized synthetic Notch receptor as an in vivo cell-cell contact sensor. Proceedings of the National Academy of Sciences of the United States of America. PMID 28490499 DOI: 10.1073/pnas.1703205114 |
0.477 |
|
| 2017 |
Chatterjee N, Perrimon N. Thermogenesis by THADA. Developmental Cell. 41: 1-2. PMID 28399393 DOI: 10.1016/J.Devcel.2017.03.021 |
0.745 |
|
| 2017 |
Chen CL, Perrimon N. Proximity-dependent labeling methods for proteomic profiling in living cells. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 28387482 DOI: 10.1002/wdev.272 |
0.319 |
|
| 2017 |
Hu Y, Comjean A, Perrimon N, Mohr SE. The Drosophila Gene Expression Tool (DGET) for expression analyses. Bmc Bioinformatics. 18: 98. PMID 28187709 DOI: 10.1186/s12859-017-1509-z |
0.347 |
|
| 2017 |
Song W, Cheng D, Hong S, Sappe B, Hu Y, Wei N, Zhu C, O'Connor MB, Pissios P, Perrimon N. Midgut-Derived Activin Regulates Glucagon-like Action in the Fat Body and Glycemic Control. Cell Metabolism. 25: 386-399. PMID 28178568 DOI: 10.1016/j.cmet.2017.01.002 |
0.41 |
|
| 2017 |
Xu C, Luo J, He L, Montell C, Perrimon N. Author response: Oxidative stress induces stem cell proliferation via TRPA1/RyR-mediated Ca2+ signaling in the Drosophila midgut Elife. DOI: 10.7554/Elife.22441.040 |
0.552 |
|
| 2017 |
Perrimon N. Abstract IA11: Combinatorial screens in Drosophila cells Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-Ia11 |
0.342 |
|
| 2016 |
Hu Y, Comjean A, Roesel C, Vinayagam A, Flockhart I, Zirin J, Perkins L, Perrimon N, Mohr SE. FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2017 update. Nucleic Acids Research. PMID 27924039 DOI: 10.1093/Nar/Gkw977 |
0.714 |
|
| 2016 |
Housden BE, Muhar M, Gemberling M, Gersbach CA, Stainier DY, Seydoux G, Mohr SE, Zuber J, Perrimon N. Loss-of-function genetic tools for animal models: cross-species and cross-platform differences. Nature Reviews. Genetics. PMID 27795562 DOI: 10.1038/Nrg.2016.118 |
0.342 |
|
| 2016 |
Droujinine IA, Perrimon N. Interorgan Communication Pathways in Physiology: Focus on Drosophila. Annual Review of Genetics. PMID 27732790 DOI: 10.1146/annurev-genet-121415-122024 |
0.775 |
|
| 2016 |
Vinayagam A, Kulkarni MM, Sopko R, Sun X, Hu Y, Nand A, Villalta C, Moghimi A, Yang X, Mohr SE, Hong P, Asara JM, Perrimon N. An Integrative Analysis of the InR/PI3K/Akt Network Identifies the Dynamic Response to Insulin Signaling. Cell Reports. 16: 3062-3074. PMID 27626673 DOI: 10.1016/J.Celrep.2016.08.029 |
0.311 |
|
| 2016 |
Housden BE, Perrimon N. Cas9-Mediated Genome Engineering in Drosophila melanogaster. Cold Spring Harbor Protocols. 2016: pdb.top086843. PMID 27587786 DOI: 10.1101/pdb.top086843 |
0.316 |
|
| 2016 |
Housden BE, Hu Y, Perrimon N. Design and Generation of Drosophila Single Guide RNA Expression Constructs. Cold Spring Harbor Protocols. 2016: pdb.prot090779. PMID 27587779 DOI: 10.1101/pdb.prot090779 |
0.341 |
|
| 2016 |
Ammeux N, Housden BE, Georgiadis A, Hu Y, Perrimon N. Mapping signaling pathway cross-talk in Drosophila cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27528688 DOI: 10.1073/pnas.1610432113 |
0.393 |
|
| 2016 |
Petsakou A, Perrimon N. "ISN't Thirst Sweet?" Says the Fly. Cell. 166: 796-7. PMID 27518557 DOI: 10.1016/j.cell.2016.07.038 |
0.773 |
|
| 2016 |
Fagegaltier D, Falciatori I, Czech B, Castel S, Perrimon N, Simcox A, Hannon GJ. Oncogenic transformation of Drosophila somatic cells induces a functional piRNA pathway. Genes & Development. 30: 1623-35. PMID 27474441 DOI: 10.1101/Gad.284927.116 |
0.394 |
|
| 2016 |
Mohr SE, Hu Y, Ewen-Campen B, Housden BE, Viswanatha R, Perrimon N. CRISPR guide RNA design for research applications. The Febs Journal. PMID 27276584 DOI: 10.1111/Febs.13777 |
0.772 |
|
| 2016 |
Hunter GL, Hadjivasiliou Z, Bonin H, He L, Perrimon N, Charras G, Baum B. Coordinated control of Notch-Delta signalling and cell cycle progression drives lateral inhibition mediated tissue patterning. Development (Cambridge, England). PMID 27226324 DOI: 10.1242/Dev.134213 |
0.49 |
|
| 2016 |
Harris KP, Zhang YV, Piccioli ZD, Perrimon N, Littleton JT. The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling. Elife. 5. PMID 27223326 DOI: 10.7554/eLife.13881 |
0.322 |
|
| 2016 |
Chavez A, Tuttle M, Pruitt BW, Ewen-Campen B, Chari R, Ter-Ovanesyan D, Haque SJ, Cecchi RJ, Kowal EJ, Buchthal J, Housden BE, Perrimon N, Collins JJ, Church G. Comparison of Cas9 activators in multiple species. Nature Methods. PMID 27214048 DOI: 10.1038/Nmeth.3871 |
0.741 |
|
| 2016 |
Vinayagam A, Gibson TE, Lee HJ, Yilmazel B, Roesel C, Hu Y, Kwon Y, Sharma A, Liu YY, Perrimon N, Barabási AL. Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets. Proceedings of the National Academy of Sciences of the United States of America. PMID 27091990 DOI: 10.1073/Pnas.1603992113 |
0.445 |
|
| 2016 |
Doupé DP, Perrimon N. Toward a Systems Understanding of Signaling Pathway Function. Current Topics in Developmental Biology. 117: 221-36. PMID 26969980 DOI: 10.1016/bs.ctdb.2015.11.005 |
0.372 |
|
| 2016 |
Perrimon N, Bonini NM, Dhillon P. Fruit flies on the front line: the translational impact of Drosophila. Disease Models & Mechanisms. 9: 229-31. PMID 26935101 DOI: 10.1242/dmm.024810 |
0.34 |
|
| 2016 |
Ma M, Zhao H, Zhao H, Binari R, Perrimon N, Li Z. Wildtype adult stem cells, unlike tumor cells, are resistant to cellular damages in Drosophila. Developmental Biology. PMID 26845534 DOI: 10.1016/j.ydbio.2016.01.040 |
0.321 |
|
| 2016 |
Breitkopf SB, Yang X, Begley MJ, Kulkarni M, Chiu YH, Turke AB, Lauriol J, Yuan M, Qi J, Engelman JA, Hong P, Kontaridis MI, Cantley LC, Perrimon N, Asara JM. A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2. Scientific Reports. 6: 20471. PMID 26839216 DOI: 10.1038/Srep20471 |
0.321 |
|
| 2015 |
Dequéant ML, Fagegaltier D, Hu Y, Spirohn K, Simcox A, Hannon GJ, Perrimon N. Discovery of progenitor cell signatures by time-series synexpression analysis during Drosophila embryonic cell immortalization. Proceedings of the National Academy of Sciences of the United States of America. PMID 26438832 DOI: 10.1073/Pnas.1517729112 |
0.396 |
|
| 2015 |
Kuhn H, Sopko R, Coughlin M, Perrimon N, Mitchison T. The Atg1-Tor pathway regulates yolk catabolism in Drosophila embryos. Development (Cambridge, England). PMID 26395483 DOI: 10.1242/Jcs.183491 |
0.348 |
|
| 2015 |
Owusu-Ansah E, Perrimon N. Stress Signaling Between Organs in Metazoa. Annual Review of Cell and Developmental Biology. PMID 26393775 DOI: 10.1146/Annurev-Cellbio-100814-125523 |
0.711 |
|
| 2015 |
Chen CL, Hu Y, Udeshi ND, Lau TY, Wirtz-Peitz F, He L, Ting AY, Carr SA, Perrimon N. Proteomic mapping in live Drosophila tissues using an engineered ascorbate peroxidase. Proceedings of the National Academy of Sciences of the United States of America. PMID 26362788 DOI: 10.1073/Pnas.1515623112 |
0.779 |
|
| 2015 |
Housden BE, Valvezan AJ, Kelley C, Sopko R, Hu Y, Roesel C, Lin S, Buckner M, Tao R, Yilmazel B, Mohr SE, Manning BD, Perrimon N. Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi. Science Signaling. 8: rs9. PMID 26350902 DOI: 10.1126/Scisignal.Aab3729 |
0.386 |
|
| 2015 |
Yan D, Perrimon N. spenito is required for sex determination in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 112: 11606-11. PMID 26324914 DOI: 10.1073/Pnas.1515891112 |
0.602 |
|
| 2015 |
Perkins LA, Holderbaum L, Tao R, Hu Y, Sopko R, McCall K, Yang-Zhou D, Flockhart I, Binari R, Shim HS, Miller A, Housden A, Foos M, Randkelv S, Kelley C, ... ... Perrimon N, et al. The Transgenic RNAi Project at Harvard Medical School: Resources and Validation. Genetics. PMID 26320097 DOI: 10.1534/Genetics.115.180208 |
0.589 |
|
| 2015 |
Lin S, Ewen-Campen B, Ni X, Housden BE, Perrimon N. In Vivo Transcriptional Activation Using CRISPR-Cas9 in Drosophila. Genetics. PMID 26245833 DOI: 10.1534/Genetics.115.181065 |
0.748 |
|
| 2015 |
Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, ... ... Perrimon N, et al. BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science (New York, N.Y.). 349: 927-9. PMID 26229113 DOI: 10.1126/Science.Aac7932 |
0.488 |
|
| 2015 |
Mohr SE, Hu Y, Rudd K, Buckner M, Gilly Q, Foster B, Sierzputowska K, Comjean A, Ye B, Perrimon N. Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells. G3 (Bethesda, Md.). PMID 26199285 DOI: 10.1534/g3.115.019364 |
0.351 |
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| 2015 |
Gordon WR, Zimmerman B, He L, Miles LJ, Huang J, Tiyanont K, McArthur DG, Aster JC, Perrimon N, Loparo JJ, Blacklow SC. Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch. Developmental Cell. 33: 729-36. PMID 26051539 DOI: 10.1016/J.Devcel.2015.05.004 |
0.415 |
|
| 2015 |
Kwon Y, Song W, Droujinine IA, Hu Y, Asara JM, Perrimon N. Systemic organ wasting induced by localized expression of the secreted insulin/IGF antagonist ImpL2. Developmental Cell. 33: 36-46. PMID 25850671 DOI: 10.1016/J.Devcel.2015.02.012 |
0.791 |
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| 2015 |
Sopko R, Lin YB, Makhijani K, Alexander B, Perrimon N, Brückner K. A systems-level interrogation identifies regulators of Drosophila blood cell number and survival. Plos Genetics. 11: e1005056. PMID 25749252 DOI: 10.1371/journal.pgen.1005056 |
0.695 |
|
| 2015 |
Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, P R Iyer E, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon N, et al. Highly efficient Cas9-mediated transcriptional programming. Nature Methods. 12: 326-8. PMID 25730490 DOI: 10.1038/Nmeth.3312 |
0.346 |
|
| 2015 |
Zirin J, Nieuwenhuis J, Samsonova A, Tao R, Perrimon N. Regulators of autophagosome formation in Drosophila muscles. Plos Genetics. 11: e1005006. PMID 25692684 DOI: 10.1371/Journal.Pgen.1005006 |
0.726 |
|
| 2015 |
Leshchiner ES, Parkhitko A, Bird GH, Luccarelli J, Bellairs JA, Escudero S, Opoku-Nsiah K, Godes M, Perrimon N, Walensky LD. Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices. Proceedings of the National Academy of Sciences of the United States of America. 112: 1761-6. PMID 25624485 DOI: 10.1073/Pnas.1413185112 |
0.319 |
|
| 2014 |
Housden BE, Lin S, Perrimon N. Cas9-based genome editing in Drosophila. Methods in Enzymology. 546: 415-39. PMID 25398351 DOI: 10.1016/B978-0-12-801185-0.00019-2 |
0.314 |
|
| 2014 |
Sopko R, Foos M, Vinayagam A, Zhai B, Binari R, Hu Y, Randklev S, Perkins LA, Gygi SP, Perrimon N. Combining genetic perturbations and proteomics to examine kinase-phosphatase networks in Drosophila embryos. Developmental Cell. 31: 114-27. PMID 25284370 DOI: 10.1016/J.Devcel.2014.07.027 |
0.307 |
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| 2014 |
Droujinine IA, Yan D, Perrimon N. A sharp end to sugary Wingless travels. The Journal of Cell Biology. 206: 819-21. PMID 25267292 DOI: 10.1083/Jcb.201408115 |
0.783 |
|
| 2014 |
Amcheslavsky A, Song W, Li Q, Nie Y, Bragatto I, Ferrandon D, Perrimon N, Ip YT. Enteroendocrine cells support intestinal stem-cell-mediated homeostasis in Drosophila. Cell Reports. 9: 32-9. PMID 25263551 DOI: 10.1016/j.celrep.2014.08.052 |
0.359 |
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| 2014 |
Gerstein MB, Rozowsky J, Yan KK, Wang D, Cheng C, Brown JB, Davis CA, Hillier L, Sisu C, Li JJ, Pei B, Harmanci AO, Duff MO, Djebali S, Alexander RP, ... ... Perrimon N, et al. Comparative analysis of the transcriptome across distant species. Nature. 512: 445-8. PMID 25164755 DOI: 10.1038/Nature13424 |
0.515 |
|
| 2014 |
Housden BE, Perrimon N. Spatial and temporal organization of signaling pathways. Trends in Biochemical Sciences. 39: 457-64. PMID 25155749 DOI: 10.1016/j.tibs.2014.07.008 |
0.349 |
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| 2014 |
Mohr SE, Smith JA, Shamu CE, Neumüller RA, Perrimon N. RNAi screening comes of age: improved techniques and complementary approaches. Nature Reviews. Molecular Cell Biology. 15: 591-600. PMID 25145850 DOI: 10.1038/nrm3860 |
0.362 |
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| 2014 |
Yilmazel B, Hu Y, Sigoillot F, Smith JA, Shamu CE, Perrimon N, Mohr SE. Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis. Bmc Bioinformatics. 15: 192. PMID 24934636 DOI: 10.1186/1471-2105-15-192 |
0.347 |
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| 2014 |
Zhou R, Mohr S, Hannon GJ, Perrimon N. Inducing RNAi in Drosophila cells by soaking with dsRNA. Cold Spring Harbor Protocols. 2014. PMID 24786505 DOI: 10.1101/Pdb.Prot080747 |
0.335 |
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| 2014 |
Doupé DP, Perrimon N. Visualizing and manipulating temporal signaling dynamics with fluorescence-based tools. Science Signaling. 7: re1. PMID 24692594 DOI: 10.1126/scisignal.2005077 |
0.36 |
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| 2014 |
Brown JB, Boley N, Eisman R, May GE, Stoiber MH, Duff MO, Booth BW, Wen J, Park S, Suzuki AM, Wan KH, Yu C, Zhang D, Carlson JW, Cherbas L, ... ... Perrimon N, et al. Diversity and dynamics of the Drosophila transcriptome. Nature. 512: 393-9. PMID 24670639 DOI: 10.1038/Nature12962 |
0.527 |
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| 2014 |
Mohr SE, Hu Y, Kim K, Housden BE, Perrimon N. Resources for functional genomics studies in Drosophila melanogaster. Genetics. 197: 1-18. PMID 24653003 DOI: 10.1534/genetics.113.154344 |
0.317 |
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| 2014 |
Griffin R, Binari R, Perrimon N. Genetic odyssey to generate marked clones in Drosophila mosaics. Proceedings of the National Academy of Sciences of the United States of America. 111: 4756-63. PMID 24623854 DOI: 10.1073/pnas.1403218111 |
0.334 |
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| 2014 |
Markstein M, Dettorre S, Cho J, Neumüller RA, Craig-Müller S, Perrimon N. Systematic screen of chemotherapeutics in Drosophila stem cell tumors. Proceedings of the National Academy of Sciences of the United States of America. 111: 4530-5. PMID 24616500 DOI: 10.1073/pnas.1401160111 |
0.78 |
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| 2014 |
Owusu-Ansah E, Perrimon N. Modeling metabolic homeostasis and nutrient sensing in Drosophila: implications for aging and metabolic diseases. Disease Models & Mechanisms. 7: 343-50. PMID 24609035 DOI: 10.1242/Dmm.012989 |
0.699 |
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| 2014 |
Yan D, Neumüller RA, Buckner M, Ayers K, Li H, Hu Y, Yang-Zhou D, Pan L, Wang X, Kelley C, Vinayagam A, Binari R, Randklev S, Perkins LA, Xie T, ... ... Perrimon N, et al. A regulatory network of Drosophila germline stem cell self-renewal. Developmental Cell. 28: 459-73. PMID 24576427 DOI: 10.1016/J.Devcel.2014.01.020 |
0.613 |
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| 2014 |
Vinayagam A, Zirin J, Roesel C, Hu Y, Yilmazel B, Samsonova AA, Neumüller RA, Mohr SE, Perrimon N. Integrating protein-protein interaction networks with phenotypes reveals signs of interactions. Nature Methods. 11: 94-9. PMID 24240319 DOI: 10.1038/Nmeth.2733 |
0.714 |
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| 2014 |
Shulman JM, Imboywa S, Giagtzoglou N, Powers MP, Hu Y, Devenport D, Chipendo P, Chibnik LB, Diamond A, Perrimon N, Brown NH, De Jager PL, Feany MB. Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. Human Molecular Genetics. 23: 870-7. PMID 24067533 DOI: 10.1093/Hmg/Ddt478 |
0.331 |
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| 2014 |
Tipping M, Perrimon N. Drosophila as a model for context-dependent tumorigenesis. Journal of Cellular Physiology. 229: 27-33. PMID 23836429 DOI: 10.1002/jcp.24427 |
0.759 |
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| 2014 |
Perrimon N. Signaling in time and space Bmc Genomics. 15. DOI: 10.1186/1471-2164-15-S2-O18 |
0.388 |
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| 2013 |
Sun X, Hong P, Kulkarni M, Kwon Y, Perrimon N. PPIRank - an advanced method for ranking protein-protein interations in TAP/MS data. Proteome Science. 11: S16. PMID 24565074 DOI: 10.1186/1477-5956-11-S1-S16 |
0.375 |
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| 2013 |
Droujinine IA, Perrimon N. Defining the interorgan communication network: systemic coordination of organismal cellular processes under homeostasis and localized stress. Frontiers in Cellular and Infection Microbiology. 3: 82. PMID 24312902 DOI: 10.3389/fcimb.2013.00082 |
0.792 |
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| 2013 |
Zirin J, Nieuwenhuis J, Perrimon N. Role of autophagy in glycogen breakdown and its relevance to chloroquine myopathy. Plos Biology. 11: e1001708. PMID 24265594 DOI: 10.1371/Journal.Pbio.1001708 |
0.705 |
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| 2013 |
Owusu-Ansah E, Song W, Perrimon N. Muscle mitohormesis promotes longevity via systemic repression of insulin signaling. Cell. 155: 699-712. PMID 24243023 DOI: 10.1016/J.Cell.2013.09.021 |
0.693 |
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| 2013 |
Ren X, Sun J, Housden BE, Hu Y, Roesel C, Lin S, Liu LP, Yang Z, Mao D, Sun L, Wu Q, Ji JY, Xi J, Mohr SE, Xu J, ... Perrimon N, et al. Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9. Proceedings of the National Academy of Sciences of the United States of America. 110: 19012-7. PMID 24191015 DOI: 10.1073/Pnas.1318481110 |
0.321 |
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| 2013 |
Kwon Y, Vinayagam A, Sun X, Dephoure N, Gygi SP, Hong P, Perrimon N. The Hippo signaling pathway interactome. Science (New York, N.Y.). 342: 737-40. PMID 24114784 DOI: 10.1126/Science.1243971 |
0.483 |
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| 2013 |
Xiong XP, Kurthkoti K, Chang KY, Lichinchi G, De N, Schneemann A, MacRae IJ, Rana TM, Perrimon N, Zhou R. Core small nuclear ribonucleoprotein particle splicing factor SmD1 modulates RNA interference in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 110: 16520-5. PMID 24067655 DOI: 10.1073/Pnas.1315803110 |
0.352 |
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| 2013 |
Zirin J, Cheng D, Dhanyasi N, Cho J, Dura JM, Vijayraghavan K, Perrimon N. Ecdysone signaling at metamorphosis triggers apoptosis of Drosophila abdominal muscles. Developmental Biology. 383: 275-84. PMID 24051228 DOI: 10.1016/J.Ydbio.2013.08.029 |
0.705 |
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| 2013 |
Neumüller RA, Gross T, Samsonova AA, Vinayagam A, Buckner M, Founk K, Hu Y, Sharifpoor S, Rosebrock AP, Andrews B, Winston F, Perrimon N. Conserved regulators of nucleolar size revealed by global phenotypic analyses. Science Signaling. 6: ra70. PMID 23962978 DOI: 10.1126/Scisignal.2004145 |
0.367 |
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| 2013 |
Hu Y, Sopko R, Foos M, Kelley C, Flockhart I, Ammeux N, Wang X, Perkins L, Perrimon N, Mohr SE. FlyPrimerBank: an online database for Drosophila melanogaster gene expression analysis and knockdown evaluation of RNAi reagents. G3 (Bethesda, Md.). 3: 1607-16. PMID 23893746 DOI: 10.1534/G3.113.007021 |
0.347 |
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| 2013 |
Hu Y, Roesel C, Flockhart I, Perkins L, Perrimon N, Mohr SE. UP-TORR: online tool for accurate and Up-to-Date annotation of RNAi Reagents. Genetics. 195: 37-45. PMID 23792952 DOI: 10.1534/Genetics.113.151340 |
0.361 |
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| 2013 |
Yin Z, Sadok A, Sailem H, McCarthy A, Xia X, Li F, Garcia MA, Evans L, Barr AR, Perrimon N, Marshall CJ, Wong ST, Bakal C. A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes. Nature Cell Biology. 15: 860-71. PMID 23748611 DOI: 10.1038/Ncb2764 |
0.681 |
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| 2013 |
Silva-Ayala D, López T, Gutiérrez M, Perrimon N, López S, Arias CF. Genome-wide RNAi screen reveals a role for the ESCRT complex in rotavirus cell entry. Proceedings of the National Academy of Sciences of the United States of America. 110: 10270-5. PMID 23733942 DOI: 10.1073/pnas.1304932110 |
0.384 |
|
| 2013 |
Zhou R, Mohr S, Hannon GJ, Perrimon N. Inducing RNAi in Drosophila cells by transfection with dsRNA. Cold Spring Harbor Protocols. 2013: 461-3. PMID 23637371 DOI: 10.1101/Pdb.Prot074351 |
0.369 |
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| 2013 |
Rajan A, Perrimon N. Of flies and men: insights on organismal metabolism from fruit flies. Bmc Biology. 11: 38. PMID 23587196 DOI: 10.1186/1741-7007-11-38 |
0.559 |
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| 2013 |
Karpowicz P, Zhang Y, Hogenesch JB, Emery P, Perrimon N. The circadian clock gates the intestinal stem cell regenerative state. Cell Reports. 3: 996-1004. PMID 23583176 DOI: 10.1016/J.Celrep.2013.03.016 |
0.713 |
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| 2013 |
Bergwitz C, Wee MJ, Sinha S, Huang J, DeRobertis C, Mensah LB, Cohen J, Friedman A, Kulkarni M, Hu Y, Vinayagam A, Schnall-Levin M, Berger B, Perkins LA, Mohr SE, ... Perrimon N, et al. Genetic determinants of phosphate response in Drosophila. Plos One. 8: e56753. PMID 23520455 DOI: 10.1371/Journal.Pone.0056753 |
0.578 |
|
| 2013 |
Vinayagam A, Hu Y, Kulkarni M, Roesel C, Sopko R, Mohr SE, Perrimon N. Protein complex-based analysis framework for high-throughput data sets. Science Signaling. 6: rs5. PMID 23443684 DOI: 10.1126/Scisignal.2003629 |
0.339 |
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| 2013 |
Roti G, Carlton A, Ross KN, Markstein M, Pajcini K, Su AH, Perrimon N, Pear WS, Kung AL, Blacklow SC, Aster JC, Stegmaier K. Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer. Cancer Cell. 23: 390-405. PMID 23434461 DOI: 10.1016/J.Ccr.2013.01.015 |
0.784 |
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| 2013 |
Pitsouli C, Perrimon N. The homeobox transcription factor cut coordinates patterning and growth during Drosophila airway remodeling. Science Signaling. 6: ra12. PMID 23423438 DOI: 10.1126/scisignal.2003424 |
0.802 |
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| 2013 |
Yeh JT, Binari R, Gocha T, Dasgupta R, Perrimon N. PAPTi: a peptide aptamer interference toolkit for perturbation of protein-protein interaction networks. Scientific Reports. 3: 1156. PMID 23362456 DOI: 10.1038/Srep01156 |
0.332 |
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| 2013 |
Staller MV, Yan D, Randklev S, Bragdon MD, Wunderlich ZB, Tao R, Perkins LA, Depace AH, Perrimon N. Depleting gene activities in early Drosophila embryos with the "maternal-Gal4-shRNA" system. Genetics. 193: 51-61. PMID 23105012 DOI: 10.1534/Genetics.112.144915 |
0.604 |
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| 2013 |
Perrimon N. Abstract IA4: Synthetic lethal screens in Drosophila Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-Ia4 |
0.399 |
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| 2012 |
Rajan A, Perrimon N. Drosophila cytokine unpaired 2 regulates physiological homeostasis by remotely controlling insulin secretion. Cell. 151: 123-37. PMID 23021220 DOI: 10.1016/J.Cell.2012.08.019 |
0.557 |
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| 2012 |
Stender JD, Pascual G, Liu W, Kaikkonen MU, Do K, Spann NJ, Boutros M, Perrimon N, Rosenfeld MG, Glass CK. Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20. Molecular Cell. 48: 28-38. PMID 22921934 DOI: 10.1016/J.Molcel.2012.07.020 |
0.331 |
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| 2012 |
Perrimon N, Pitsouli C, Shilo BZ. Signaling mechanisms controlling cell fate and embryonic patterning. Cold Spring Harbor Perspectives in Biology. 4: a005975. PMID 22855721 DOI: 10.1101/Cshperspect.A005975 |
0.805 |
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| 2012 |
Kusche-Gullberg M, Nybakken K, Perrimon N, Lindahl U. Drosophila heparan sulfate, a novel design. The Journal of Biological Chemistry. 287: 21950-6. PMID 22556423 DOI: 10.1074/jbc.M112.350389 |
0.317 |
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| 2012 |
Bergwitz C, Rasmussen MD, DeRobertis C, Wee MJ, Sinha S, Chen HH, Huang J, Perrimon N. Roles of major facilitator superfamily transporters in phosphate response in Drosophila. Plos One. 7: e31730. PMID 22359624 DOI: 10.1371/journal.pone.0031730 |
0.333 |
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| 2012 |
Neumüller RA, Wirtz-Peitz F, Lee S, Kwon Y, Buckner M, Hoskins RA, Venken KJ, Bellen HJ, Mohr SE, Perrimon N. Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes. Genetics. 190: 931-40. PMID 22174071 DOI: 10.1534/Genetics.111.136465 |
0.795 |
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| 2012 |
Mohr SE, Perrimon N. RNAi screening: new approaches, understandings, and organisms. Wiley Interdisciplinary Reviews. Rna. 3: 145-58. PMID 21953743 DOI: 10.1002/wrna.110 |
0.345 |
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| 2011 |
Friedman AA, Tucker G, Singh R, Yan D, Vinayagam A, Hu Y, Binari R, Hong P, Sun X, Porto M, Pacifico S, Murali T, Finley RL, Asara JM, Berger B, ... Perrimon N, et al. Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling. Science Signaling. 4: rs10. PMID 22028469 DOI: 10.1126/Scisignal.2002029 |
0.729 |
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| 2011 |
Rohn JL, Sims D, Liu T, Fedorova M, Schöck F, Dopie J, Vartiainen MK, Kiger AA, Perrimon N, Baum B. Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype. The Journal of Cell Biology. 194: 789-805. PMID 21893601 DOI: 10.1083/jcb.201103168 |
0.673 |
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| 2011 |
Hu Y, Flockhart I, Vinayagam A, Bergwitz C, Berger B, Perrimon N, Mohr SE. An integrative approach to ortholog prediction for disease-focused and other functional studies. Bmc Bioinformatics. 12: 357. PMID 21880147 DOI: 10.1186/1471-2105-12-357 |
0.342 |
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| 2011 |
Rajan A, Perrimon N. Drosophila as a model for interorgan communication: lessons from studies on energy homeostasis. Developmental Cell. 21: 29-31. PMID 21763605 DOI: 10.1016/J.Devcel.2011.06.034 |
0.555 |
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| 2011 |
Ni JQ, Zhou R, Czech B, Liu LP, Holderbaum L, Yang-Zhou D, Shim HS, Tao R, Handler D, Karpowicz P, Binari R, Booker M, Brennecke J, Perkins LA, Hannon GJ, ... Perrimon N, et al. A genome-scale shRNA resource for transgenic RNAi in Drosophila. Nature Methods. 8: 405-7. PMID 21460824 DOI: 10.1038/Nmeth.1592 |
0.712 |
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| 2011 |
Perrimon N, Zirin J, Bai J. Primary cell cultures from Drosophila gastrula embryos. Journal of Visualized Experiments : Jove. PMID 21403631 DOI: 10.3791/2215 |
0.724 |
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| 2011 |
Chan WM, Tsoi H, Wu CC, Wong CH, Cheng TC, Li HY, Lau KF, Shaw PC, Perrimon N, Chan HY. Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1. Human Molecular Genetics. 20: 1738-50. PMID 21300695 DOI: 10.1093/Hmg/Ddr049 |
0.32 |
|
| 2011 |
Gibson WT, Veldhuis JH, Rubinstein B, Cartwright HN, Perrimon N, Brodland GW, Nagpal R, Gibson MC. Control of the mitotic cleavage plane by local epithelial topology. Cell. 144: 427-38. PMID 21295702 DOI: 10.1016/J.Cell.2010.12.035 |
0.68 |
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| 2011 |
Booker M, Samsonova AA, Kwon Y, Flockhart I, Mohr SE, Perrimon N. False negative rates in Drosophila cell-based RNAi screens: a case study. Bmc Genomics. 12: 50. PMID 21251254 DOI: 10.1186/1471-2164-12-50 |
0.457 |
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| 2011 |
Kondo S, Perrimon N. A genome-wide RNAi screen identifies core components of the Gâ‚‚-M DNA damage checkpoint. Science Signaling. 4: rs1. PMID 21205937 DOI: 10.1126/scisignal.2001350 |
0.312 |
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| 2011 |
Neumüller RA, Perrimon N. Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 471-8. PMID 21197652 DOI: 10.1002/wsbm.127 |
0.364 |
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| 2011 |
Graveley BR, Brooks AN, Carlson JW, Duff MO, Landolin JM, Yang L, Artieri CG, van Baren MJ, Boley N, Booth BW, Brown JB, Cherbas L, Davis CA, Dobin A, Li R, ... ... Perrimon N, et al. The developmental transcriptome of Drosophila melanogaster. Nature. 471: 473-9. PMID 21179090 DOI: 10.1038/Nature09715 |
0.514 |
|
| 2011 |
Cherbas L, Willingham A, Zhang D, Yang L, Zou Y, Eads BD, Carlson JW, Landolin JM, Kapranov P, Dumais J, Samsonova A, Choi JH, Roberts J, Davis CA, Tang H, ... ... Perrimon N, et al. The transcriptional diversity of 25 Drosophila cell lines. Genome Research. 21: 301-14. PMID 21177962 DOI: 10.1101/Gr.112961.110 |
0.369 |
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| 2011 |
Micchelli CA, Sudmeier L, Perrimon N, Tang S, Beehler-Evans R. Identification of adult midgut precursors in Drosophila. Gene Expression Patterns : Gep. 11: 12-21. PMID 20804858 DOI: 10.1016/J.Gep.2010.08.005 |
0.587 |
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| 2011 |
Roti G, Carlton A, Ross KN, Markstein M, Pajcini K, Perrimon N, Kung AL, Pear WS, Blacklow SC, Aster JC, Stegmaier K. Intersecting High-Throughput Screens Identifies SERCA As a Target for Modulating NOTCH1 In Hematopoietic Malignancies Blood. 118: 555-555. DOI: 10.1182/Blood.V118.21.555.555 |
0.403 |
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| 2011 |
Yang X, Locasale J, Rahal R, Breitkopf S, VanderHeiden M, Spentzos D, Wu C, Perrimon N, Cantley L, Wong E, Asara J. Abstract LB-255: A mass spectrometry platform to quantitatively profile cancer cell metabolism from cells, tumors, and fixed tissue Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-255 |
0.323 |
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| 2011 |
Friedman AA, Perrimon N, VanHook AM. Science Signaling Podcast: 25 October 2011 Science Signaling. 4: pc22-pc22. DOI: 10.1126/Scisignal.2002560 |
0.571 |
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| 2011 |
Perrimon N. Deciphering Gene Expression Patterns Developmental Cell. 21: e1. DOI: 10.1016/j.devcel.2011.10.002 |
0.341 |
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| 2010 |
Roy S, Ernst J, Kharchenko PV, Kheradpour P, Negre N, Eaton ML, Landolin JM, Bristow CA, Ma L, Lin MF, Washietl S, Arshinoff BI, Ay F, Meyer PE, ... ... Perrimon N, et al. Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (New York, N.Y.). 330: 1787-97. PMID 21177974 DOI: 10.1126/Science.1198374 |
0.679 |
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| 2010 |
Karpowicz P, Perrimon N. All for one, and one for all: the clonality of the intestinal stem cell niche. F1000 Biology Reports. 2: 73. PMID 21173846 DOI: 10.3410/B2-73 |
0.717 |
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| 2010 |
Rui Y, Bai J, Perrimon N. Sarcomere formation occurs by the assembly of multiple latent protein complexes. Plos Genetics. 6: e1001208. PMID 21124995 DOI: 10.1371/journal.pgen.1001208 |
0.314 |
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| 2010 |
Karpowicz P, Perez J, Perrimon N. The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration. Development (Cambridge, England). 137: 4135-45. PMID 21098564 DOI: 10.1242/dev.060483 |
0.734 |
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| 2010 |
Pitsouli C, Perrimon N. Embryonic multipotent progenitors remodel the Drosophila airways during metamorphosis. Development (Cambridge, England). 137: 3615-24. PMID 20940225 DOI: 10.1242/dev.056408 |
0.794 |
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| 2010 |
Zirin J, Perrimon N. Drosophila as a model system to study autophagy. Seminars in Immunopathology. 32: 363-72. PMID 20798940 DOI: 10.1007/S00281-010-0223-Y |
0.725 |
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| 2010 |
Yan H, Venkatesan K, Beaver JE, Klitgord N, Yildirim MA, Hao T, Hill DE, Cusick ME, Perrimon N, Roth FP, Vidal M. A genome-wide gene function prediction resource for Drosophila melanogaster. Plos One. 5: e12139. PMID 20711346 DOI: 10.1371/Journal.Pone.0012139 |
0.338 |
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| 2010 |
Rajan A, Perrimon N. Steroids make you bigger? Fat chance says Myc. Cell Metabolism. 12: 7-9. PMID 20620990 DOI: 10.1016/J.Cmet.2010.06.003 |
0.534 |
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| 2010 |
Kockel L, Kerr KS, Melnick M, Brückner K, Hebrok M, Perrimon N. Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling. Plos Genetics. 6: e1000990. PMID 20585550 DOI: 10.1371/Journal.Pgen.1000990 |
0.804 |
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| 2010 |
Perrimon N, Ni JQ, Perkins L. In vivo RNAi: today and tomorrow. Cold Spring Harbor Perspectives in Biology. 2: a003640. PMID 20534712 DOI: 10.1101/Cshperspect.A003640 |
0.346 |
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| 2010 |
Bakal C, Perrimon N. Realizing the promise of RNAi high throughput screening. Developmental Cell. 18: 506-7. PMID 20412765 DOI: 10.1016/J.Devcel.2010.04.005 |
0.63 |
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| 2010 |
Mohr S, Bakal C, Perrimon N. Genomic screening with RNAi: results and challenges. Annual Review of Biochemistry. 79: 37-64. PMID 20367032 DOI: 10.1146/Annurev-Biochem-060408-092949 |
0.665 |
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| 2010 |
Nir O, Bakal C, Perrimon N, Berger B. Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen. Genome Research. 20: 372-80. PMID 20144944 DOI: 10.1101/Gr.100248.109 |
0.668 |
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| 2010 |
Zhang S, Binari R, Zhou R, Perrimon N. A genomewide RNA interference screen for modifiers of aggregates formation by mutant Huntingtin in Drosophila. Genetics. 184: 1165-79. PMID 20100940 DOI: 10.1534/Genetics.109.112516 |
0.366 |
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| 2009 |
Yang X, Friedman A, Nagpal S, Perrimon N, Asara JM. Use of a label-free quantitative platform based on MS/MS average TIC to calculate dynamics of protein complexes in insulin signaling. Journal of Biomolecular Techniques : Jbt. 20: 272-7. PMID 19949701 |
0.429 |
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| 2009 |
Apidianakis Y, Pitsouli C, Perrimon N, Rahme L. Synergy between bacterial infection and genetic predisposition in intestinal dysplasia. Proceedings of the National Academy of Sciences of the United States of America. 106: 20883-8. PMID 19934041 DOI: 10.1073/Pnas.0911797106 |
0.78 |
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| 2009 |
Pitsouli C, Apidianakis Y, Perrimon N. Homeostasis in infected epithelia: stem cells take the lead. Cell Host & Microbe. 6: 301-7. PMID 19837370 DOI: 10.1016/J.Chom.2009.10.001 |
0.786 |
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| 2009 |
Bai J, Sepp KJ, Perrimon N. Culture of Drosophila primary cells dissociated from gastrula embryos and their use in RNAi screening. Nature Protocols. 4: 1502-12. PMID 19798083 DOI: 10.1038/nprot.2009.147 |
0.368 |
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| 2009 |
Kondo S, Booker M, Perrimon N. Cross-species RNAi rescue platform in Drosophila melanogaster. Genetics. 183: 1165-73. PMID 19720858 DOI: 10.1534/genetics.109.106567 |
0.366 |
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| 2009 |
Vinegoni C, Razansky D, Pitsouli C, Perrimon N, Ntziachristos V, Weissleder R. Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila. Journal of Visualized Experiments : Jove. PMID 19696720 DOI: 10.3791/1510 |
0.765 |
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| 2009 |
Zhou R, Czech B, Brennecke J, Sachidanandam R, Wohlschlegel JA, Perrimon N, Hannon GJ. Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform. Rna (New York, N.Y.). 15: 1886-95. PMID 19635780 DOI: 10.1261/Rna.1611309 |
0.305 |
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| 2009 |
Griffin R, Sustar A, Bonvin M, Binari R, del Valle Rodriguez A, Hohl AM, Bateman JR, Villalta C, Heffern E, Grunwald D, Bakal C, Desplan C, Schubiger G, Wu CT, Perrimon N. The twin spot generator for differential Drosophila lineage analysis. Nature Methods. 6: 600-2. PMID 19633664 DOI: 10.1038/Nmeth.1349 |
0.753 |
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| 2009 |
Brouzes E, Medkova M, Savenelli N, Marran D, Twardowski M, Hutchison JB, Rothberg JM, Link DR, Perrimon N, Samuels ML. Droplet microfluidic technology for single-cell high-throughput screening. Proceedings of the National Academy of Sciences of the United States of America. 106: 14195-200. PMID 19617544 DOI: 10.1073/pnas.0903542106 |
0.313 |
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| 2009 |
Kaplow IM, Singh R, Friedman A, Bakal C, Perrimon N, Berger B. RNAiCut: automated detection of significant genes from functional genomic screens. Nature Methods. 6: 476-7. PMID 19564846 DOI: 10.1038/Nmeth0709-476 |
0.713 |
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| 2009 |
Ni JQ, Liu LP, Binari R, Hardy R, Shim HS, Cavallaro A, Booker M, Pfeiffer BD, Markstein M, Wang H, Villalta C, Laverty TR, Perkins LA, Perrimon N. A Drosophila resource of transgenic RNAi lines for neurogenetics. Genetics. 182: 1089-100. PMID 19487563 DOI: 10.1534/Genetics.109.103630 |
0.79 |
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| 2009 |
Zhang S, Feany MB, Saraswati S, Littleton JT, Perrimon N. Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model. Disease Models & Mechanisms. 2: 247-66. PMID 19380309 DOI: 10.1242/Dmm.000653 |
0.305 |
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| 2009 |
Demontis F, Perrimon N. Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila. Development (Cambridge, England). 136: 983-93. PMID 19211682 DOI: 10.1242/dev.027466 |
0.306 |
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| 2009 |
Wang J, Zhou X, Li F, Bradley PL, Chang SF, Perrimon N, Wong ST. An image score inference system for RNAi genome-wide screening based on fuzzy mixture regression modeling. Journal of Biomedical Informatics. 42: 32-40. PMID 18547870 DOI: 10.1016/J.Jbi.2008.04.007 |
0.314 |
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| 2008 |
Zhou R, Hotta I, Denli AM, Hong P, Perrimon N, Hannon GJ. Comparative analysis of argonaute-dependent small RNA pathways in Drosophila. Molecular Cell. 32: 592-9. PMID 19026789 DOI: 10.1016/J.Molcel.2008.10.018 |
0.321 |
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| 2008 |
Bakal C, Linding R, Llense F, Heffern E, Martin-Blanco E, Pawson T, Perrimon N. Phosphorylation networks regulating JNK activity in diverse genetic backgrounds. Science (New York, N.Y.). 322: 453-6. PMID 18927396 DOI: 10.1126/Science.1158739 |
0.658 |
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| 2008 |
Pitsouli C, Perrimon N. Developmental biology: Our fly cousins' gut. Nature. 454: 592-3. PMID 18668098 DOI: 10.1038/454592a |
0.775 |
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| 2008 |
Vincent S, Perrimon N, Axelrod JD. Hedgehog and Wingless stabilize but do not induce cell fate during Drosophila dorsal embryonic epidermal patterning. Development (Cambridge, England). 135: 2767-75. PMID 18614578 DOI: 10.1242/Dev.017814 |
0.791 |
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| 2008 |
Sepp KJ, Hong P, Lizarraga SB, Liu JS, Mejia LA, Walsh CA, Perrimon N. Identification of neural outgrowth genes using genome-wide RNAi. Plos Genetics. 4: e1000111. PMID 18604272 DOI: 10.1371/Journal.Pgen.1000111 |
0.397 |
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| 2008 |
Yin Z, Zhou X, Bakal C, Li F, Sun Y, Perrimon N, Wong ST. Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens. Bmc Bioinformatics. 9: 264. PMID 18534020 DOI: 10.1186/1471-2105-9-264 |
0.652 |
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| 2008 |
Bai J, Binari R, Ni JQ, Vijayakanthan M, Li HS, Perrimon N. RNA interference screening in Drosophila primary cells for genes involved in muscle assembly and maintenance. Development (Cambridge, England). 135: 1439-49. PMID 18359903 DOI: 10.1242/Dev.012849 |
0.364 |
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| 2008 |
Markstein M, Pitsouli C, Villalta C, Celniker SE, Perrimon N. Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes. Nature Genetics. 40: 476-83. PMID 18311141 DOI: 10.1038/ng.101 |
0.789 |
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| 2008 |
Philips JA, Porto MC, Wang H, Rubin EJ, Perrimon N. ESCRT factors restrict mycobacterial growth. Proceedings of the National Academy of Sciences of the United States of America. 105: 3070-5. PMID 18287038 DOI: 10.1073/Pnas.0707206105 |
0.303 |
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| 2008 |
Wang J, Zhou X, Bradley PL, Chang SF, Perrimon N, Wong ST. Cellular phenotype recognition for high-content RNA interference genome-wide screening. Journal of Biomolecular Screening. 13: 29-39. PMID 18227224 DOI: 10.1177/1087057107311223 |
0.404 |
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| 2008 |
Ni JQ, Markstein M, Binari R, Pfeiffer B, Liu LP, Villalta C, Booker M, Perkins L, Perrimon N. Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Nature Methods. 5: 49-51. PMID 18084299 DOI: 10.1038/Nmeth1146 |
0.774 |
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| 2008 |
Vinegoni C, Pitsouli C, Razansky D, Perrimon N, Ntziachristos V. In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography. Nature Methods. 5: 45-7. PMID 18066071 DOI: 10.1038/Nmeth1149 |
0.763 |
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| 2008 |
Baym M, Bakal C, Perrimon N, Berger B. High-resolution modeling of cellular signaling networks Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4955: 257-271. DOI: 10.1007/978-3-540-78839-3_22 |
0.578 |
|
| 2007 |
Perrimon N, Mathey-Prevot B. Matter arising: off-targets and genome-scale RNAi screens in Drosophila. Fly. 1: 1-5. PMID 18705022 DOI: 10.4161/Fly.3601 |
0.319 |
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| 2007 |
Bai J, Hartwig JH, Perrimon N. SALS, a WH2-domain-containing protein, promotes sarcomeric actin filament elongation from pointed ends during Drosophila muscle growth. Developmental Cell. 13: 828-42. PMID 18061565 DOI: 10.1016/j.devcel.2007.10.003 |
0.311 |
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| 2007 |
Leopold P, Perrimon N. Drosophila and the genetics of the internal milieu. Nature. 450: 186-8. PMID 17994083 DOI: 10.1038/nature06286 |
0.313 |
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| 2007 |
DasGupta R, Nybakken K, Booker M, Mathey-Prevot B, Gonsalves F, Changkakoty B, Perrimon N. A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila. Genome Biology. 8: R203. PMID 17903264 DOI: 10.1186/Gb-2007-8-9-R203 |
0.364 |
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| 2007 |
Ramadan N, Flockhart I, Booker M, Perrimon N, Mathey-Prevot B. Design and implementation of high-throughput RNAi screens in cultured Drosophila cells. Nature Protocols. 2: 2245-64. PMID 17853882 DOI: 10.1038/nprot.2007.250 |
0.315 |
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| 2007 |
Bakal C, Aach J, Church G, Perrimon N. Quantitative morphological signatures define local signaling networks regulating cell morphology. Science (New York, N.Y.). 316: 1753-6. PMID 17588932 DOI: 10.1126/Science.1140324 |
0.685 |
|
| 2007 |
Lu J, Ruhf ML, Perrimon N, Leder P. A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression. Proceedings of the National Academy of Sciences of the United States of America. 104: 9381-6. PMID 17517653 DOI: 10.1073/Pnas.0610279104 |
0.419 |
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| 2007 |
Friedman A, Perrimon N. Genetic screening for signal transduction in the era of network biology. Cell. 128: 225-31. PMID 17254958 DOI: 10.1016/J.Cell.2007.01.007 |
0.576 |
|
| 2007 |
Perrimon N, Mathey-Prevot B. Applications of high-throughput RNA interference screens to problems in cell and developmental biology. Genetics. 175: 7-16. PMID 17244760 DOI: 10.1534/genetics.106.069963 |
0.36 |
|
| 2007 |
Perrimon N, Friedman A, Mathey-Prevot B, Eggert US. Drug-target identification in Drosophila cells: combining high-throughout RNAi and small-molecule screens. Drug Discovery Today. 12: 28-33. PMID 17198970 DOI: 10.1016/J.Drudis.2006.10.006 |
0.531 |
|
| 2007 |
Bach EA, Ekas LA, Ayala-Camargo A, Flaherty MS, Lee H, Perrimon N, Baeg GH. GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo. Gene Expression Patterns : Gep. 7: 323-31. PMID 17008134 DOI: 10.1016/j.modgep.2006.08.003 |
0.61 |
|
| 2007 |
Yin Z, Zhou X, Bakal C, Li F, Sun Y, Perrimon N, Wong STC. Online phenotype discovery in high-content RNAi screens using gap statistics Aip Conference Proceedings. 952: 86-95. DOI: 10.1063/1.2816647 |
0.581 |
|
| 2006 |
Mathey-Prevot B, Perrimon N. Drosophila genome-wide RNAi screens: are they delivering the promise? Cold Spring Harbor Symposia On Quantitative Biology. 71: 141-8. PMID 17381290 DOI: 10.1101/sqb.2006.71.027 |
0.349 |
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| 2006 |
Friedman A, Perrimon N. A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling. Nature. 444: 230-4. PMID 17086199 DOI: 10.1038/Nature05280 |
0.613 |
|
| 2006 |
Cherry S, Kunte A, Wang H, Coyne C, Rawson RB, Perrimon N. COPI activity coupled with fatty acid biosynthesis is required for viral replication. Plos Pathogens. 2: e102. PMID 17040126 DOI: 10.1371/Journal.Ppat.0020102 |
0.548 |
|
| 2006 |
Echeverri CJ, Beachy PA, Baum B, Boutros M, Buchholz F, Chanda SK, Downward J, Ellenberg J, Fraser AG, Hacohen N, Hahn WC, Jackson AL, Kiger A, Linsley PS, Lum L, ... ... Perrimon N, et al. Minimizing the risk of reporting false positives in large-scale RNAi screens. Nature Methods. 3: 777-9. PMID 16990807 DOI: 10.1038/Nmeth1006-777 |
0.623 |
|
| 2006 |
Kulkarni MM, Booker M, Silver SJ, Friedman A, Hong P, Perrimon N, Mathey-Prevot B. Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays. Nature Methods. 3: 833-8. PMID 16964256 DOI: 10.1038/Nmeth935 |
0.558 |
|
| 2006 |
Gibson MC, Patel AB, Nagpal R, Perrimon N. The emergence of geometric order in proliferating metazoan epithelia. Nature. 442: 1038-41. PMID 16900102 DOI: 10.1038/Nature05014 |
0.604 |
|
| 2006 |
Friedman A, Perrimon N. High-throughput approaches to dissecting MAPK signaling pathways. Methods (San Diego, Calif.). 40: 262-71. PMID 16844385 DOI: 10.1016/J.Ymeth.2006.05.002 |
0.596 |
|
| 2006 |
Chen LY, Wang JC, Hyvert Y, Lin HP, Perrimon N, Imler JL, Hsu JC. Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo. Current Biology : Cb. 16: 1183-93. PMID 16782008 DOI: 10.1016/j.cub.2006.05.050 |
0.351 |
|
| 2006 |
Echeverri CJ, Perrimon N. High-throughput RNAi screening in cultured cells: a user's guide. Nature Reviews. Genetics. 7: 373-84. PMID 16607398 DOI: 10.1038/nrg1836 |
0.307 |
|
| 2006 |
Bard F, Casano L, Mallabiabarrena A, Wallace E, Saito K, Kitayama H, Guizzunti G, Hu Y, Wendler F, Dasgupta R, Perrimon N, Malhotra V. Functional genomics reveals genes involved in protein secretion and Golgi organization. Nature. 439: 604-7. PMID 16452979 DOI: 10.1038/Nature04377 |
0.371 |
|
| 2006 |
Flockhart I, Booker M, Kiger A, Boutros M, Armknecht S, Ramadan N, Richardson K, Xu A, Perrimon N, Mathey-Prevot B. FlyRNAi: the Drosophila RNAi screening center database. Nucleic Acids Research. 34: D489-94. PMID 16381918 DOI: 10.1093/Nar/Gkj114 |
0.651 |
|
| 2006 |
Micchelli CA, Perrimon N. Evidence that stem cells reside in the adult Drosophila midgut epithelium. Nature. 439: 475-9. PMID 16340959 DOI: 10.1038/Nature04371 |
0.624 |
|
| 2006 |
Karsten P, Plischke I, Perrimon N, Zeidler MP. Mutational analysis reveals separable DNA binding and trans-activation of Drosophila STAT92E. Cellular Signalling. 18: 819-29. PMID 16129580 DOI: 10.1016/j.cellsig.2005.07.006 |
0.335 |
|
| 2005 |
Nybakken K, Vokes SA, Lin TY, McMahon AP, Perrimon N. A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway. Nature Genetics. 37: 1323-32. PMID 16311596 DOI: 10.1038/Ng1682 |
0.405 |
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| 2005 |
Kirilly D, Spana EP, Perrimon N, Padgett RW, Xie T. BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary. Developmental Cell. 9: 651-62. PMID 16256740 DOI: 10.1016/j.devcel.2005.09.013 |
0.732 |
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| 2005 |
Häcker U, Nybakken K, Perrimon N. Heparan sulphate proteoglycans: the sweet side of development. Nature Reviews. Molecular Cell Biology. 6: 530-41. PMID 16072037 DOI: 10.1038/nrm1681 |
0.659 |
|
| 2005 |
Baeg GH, Zhou R, Perrimon N. Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila. Genes & Development. 19: 1861-70. PMID 16055650 DOI: 10.1101/gad.1320705 |
0.387 |
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| 2005 |
Agaisse H, Burrack LS, Philips JA, Rubin EJ, Perrimon N, Higgins DE. Genome-wide RNAi screen for host factors required for intracellular bacterial infection. Science (New York, N.Y.). 309: 1248-51. PMID 16020693 DOI: 10.1126/Science.1116008 |
0.306 |
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| 2005 |
Schober M, Rebay I, Perrimon N. Function of the ETS transcription factor Yan in border cell migration. Development (Cambridge, England). 132: 3493-504. PMID 16014514 DOI: 10.1242/Dev.01911 |
0.388 |
|
| 2005 |
DasGupta R, Boutros M, Perrimon N. Drosophila Wnt/Fz pathways. Science's Stke : Signal Transduction Knowledge Environment. 2005: cm5. PMID 15886387 DOI: 10.1126/Stke.2832005Cm5 |
0.403 |
|
| 2005 |
DasGupta R, Kaykas A, Moon RT, Perrimon N. Functional genomic analysis of the Wnt-wingless signaling pathway. Science (New York, N.Y.). 308: 826-33. PMID 15817814 DOI: 10.1126/Science.1109374 |
0.432 |
|
| 2005 |
Gibson MC, Perrimon N. Extrusion and death of DPP/BMP-compromised epithelial cells in the developing Drosophila wing. Science (New York, N.Y.). 307: 1785-9. PMID 15774762 DOI: 10.1126/Science.1104751 |
0.627 |
|
| 2005 |
Hayward P, Brennan K, Sanders P, Balayo T, DasGupta R, Perrimon N, Martinez Arias A. Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity. Development (Cambridge, England). 132: 1819-30. PMID 15772135 DOI: 10.1242/Dev.01724 |
0.401 |
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| 2005 |
Cherry S, Doukas T, Armknecht S, Whelan S, Wang H, Sarnow P, Perrimon N. Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition. Genes & Development. 19: 445-52. PMID 15713840 DOI: 10.1101/Gad.1267905 |
0.54 |
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| 2005 |
Armknecht S, Boutros M, Kiger A, Nybakken K, Mathey-Prevot B, Perrimon N. High-throughput RNA interference screens in Drosophila tissue culture cells. Methods in Enzymology. 392: 55-73. PMID 15644175 DOI: 10.1016/S0076-6879(04)92004-6 |
0.661 |
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| 2004 |
Eggert US, Kiger AA, Richter C, Perlman ZE, Perrimon N, Mitchison TJ, Field CM. Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. Plos Biology. 2: e379. PMID 15547975 DOI: 10.1371/Journal.Pbio.0020379 |
0.673 |
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| 2004 |
Baeg GH, Selva EM, Goodman RM, Dasgupta R, Perrimon N. The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors. Developmental Biology. 276: 89-100. PMID 15531366 DOI: 10.1016/J.Ydbio.2004.08.023 |
0.363 |
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| 2004 |
Dasgupta R, Perrimon N. Using RNAi to catch Drosophila genes in a web of interactions: insights into cancer research. Oncogene. 23: 8359-65. PMID 15517017 DOI: 10.1038/Sj.Onc.1208028 |
0.358 |
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| 2004 |
Schlesinger A, Kiger A, Perrimon N, Shilo BZ. Small wing PLCgamma is required for ER retention of cleaved Spitz during eye development in Drosophila. Developmental Cell. 7: 535-45. PMID 15469842 DOI: 10.1016/j.devcel.2004.09.001 |
0.665 |
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| 2004 |
Friedman A, Perrimon N. Genome-wide high-throughput screens in functional genomics. Current Opinion in Genetics & Development. 14: 470-6. PMID 15380236 DOI: 10.1016/J.Gde.2004.07.010 |
0.575 |
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| 2004 |
Sinenko SA, Kim EK, Wynn R, Manfruelli P, Ando I, Wharton KA, Perrimon N, Mathey-Prevot B. Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development. Developmental Biology. 273: 48-62. PMID 15302597 DOI: 10.1016/J.Ydbio.2004.05.022 |
0.383 |
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| 2004 |
Brückner K, Kockel L, Duchek P, Luque CM, Rørth P, Perrimon N. The PDGF/VEGF receptor controls blood cell survival in Drosophila. Developmental Cell. 7: 73-84. PMID 15239955 DOI: 10.1016/j.devcel.2004.06.007 |
0.347 |
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| 2004 |
Agaisse H, Perrimon N. The roles of JAK/STAT signaling in Drosophila immune responses. Immunological Reviews. 198: 72-82. PMID 15199955 DOI: 10.1111/J.0105-2896.2004.0133.X |
0.325 |
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| 2004 |
Zeidler MP, Tan C, Bellaiche Y, Cherry S, Häder S, Gayko U, Perrimon N. Temperature-sensitive control of protein activity by conditionally splicing inteins. Nature Biotechnology. 22: 871-6. PMID 15184905 DOI: 10.1038/Nbt979 |
0.748 |
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| 2004 |
Perrimon N, Häcker U. Wingless, hedgehog and heparan sulfate proteoglycans. Development (Cambridge, England). 131: 2509-11; author repl. PMID 15148297 DOI: 10.1242/dev.01225 |
0.636 |
|
| 2004 |
Boutros M, Kiger AA, Armknecht S, Kerr K, Hild M, Koch B, Haas SA, Paro R, Perrimon N. Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science (New York, N.Y.). 303: 832-5. PMID 14764878 DOI: 10.1126/science.1091266 |
0.696 |
|
| 2004 |
Cherry S, Perrimon N. Entry is a rate-limiting step for viral infection in a Drosophila melanogaster model of pathogenesis. Nature Immunology. 5: 81-7. PMID 14691479 DOI: 10.1038/Ni1019 |
0.53 |
|
| 2003 |
Bach EA, Vincent S, Zeidler MP, Perrimon N. A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway. Genetics. 165: 1149-66. PMID 14668372 |
0.709 |
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| 2003 |
Gibson MC, Perrimon N. Apicobasal polarization: epithelial form and function. Current Opinion in Cell Biology. 15: 747-52. PMID 14644201 DOI: 10.1016/J.Ceb.2003.10.008 |
0.587 |
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| 2003 |
Kiger AA, Baum B, Jones S, Jones MR, Coulson A, Echeverri C, Perrimon N. A functional genomic analysis of cell morphology using RNA interference. Journal of Biology. 2: 27. PMID 14527345 DOI: 10.1186/1475-4924-2-27 |
0.71 |
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| 2003 |
Agaisse H, Petersen UM, Boutros M, Mathey-Prevot B, Perrimon N. Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury. Developmental Cell. 5: 441-50. PMID 12967563 DOI: 10.1016/S1534-5807(03)00244-2 |
0.346 |
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| 2003 |
Sasamura T, Sasaki N, Miyashita F, Nakao S, Ishikawa HO, Ito M, Kitagawa M, Harigaya K, Spana E, Bilder D, Perrimon N, Matsuno K. neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions. Development (Cambridge, England). 130: 4785-95. PMID 12917292 DOI: 10.1242/Dev.00679 |
0.808 |
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| 2003 |
Ghiglione C, Amundadottir L, Andresdottir M, Bilder D, Diamonti JA, Noselli S, Perrimon N, Carraway III KL. Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1. Development (Cambridge, England). 130: 4483-93. PMID 12900463 DOI: 10.1242/Dev.00617 |
0.623 |
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| 2003 |
Lüders F, Segawa H, Stein D, Selva EM, Perrimon N, Turco SJ, Häcker U. Slalom encodes an adenosine 3'-phosphate 5'-phosphosulfate transporter essential for development in Drosophila. The Embo Journal. 22: 3635-44. PMID 12853478 DOI: 10.1093/Emboj/Cdg345 |
0.645 |
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| 2003 |
Bashirullah A, Pasquinelli AE, Kiger AA, Perrimon N, Ruvkun G, Thummel CS. Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis. Developmental Biology. 259: 1-8. PMID 12812783 DOI: 10.1016/S0012-1606(03)00063-0 |
0.643 |
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| 2003 |
Adám G, Perrimon N, Noselli S. The retinoic-like juvenile hormone controls the looping of left-right asymmetric organs in Drosophila. Development (Cambridge, England). 130: 2397-406. PMID 12702654 DOI: 10.1242/Dev.00460 |
0.315 |
|
| 2003 |
Bilder D, Schober M, Perrimon N. Integrated activity of PDZ protein complexes regulates epithelial polarity. Nature Cell Biology. 5: 53-8. PMID 12510194 DOI: 10.1038/ncb897 |
0.618 |
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| 2003 |
Tan C, Stronach B, Perrimon N. Roles of myosin phosphatase during Drosophila development. Development (Cambridge, England). 130: 671-81. PMID 12505998 DOI: 10.1242/Dev.00298 |
0.755 |
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| 2003 |
Micchelli CA, Esler WP, Kimberly WT, Jack C, Berezovska O, Kornilova A, Hyman BT, Perrimon N, Wolfe MS. Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 79-81. PMID 12424225 DOI: 10.1096/Fj.02-0394Fje |
0.574 |
|
| 2003 |
Stronach BE, Perrimon N. Developmental Signaling: JNK Pathway in Drosophila Morphogenesis Handbook of Cell Signaling. 2: 783-787. DOI: 10.1016/B978-012124546-7/50612-4 |
0.713 |
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| 2002 |
Lin X, Perrimon N. Developmental roles of heparan sulfate proteoglycans in Drosophila. Glycoconjugate Journal. 19: 363-8. PMID 12975617 DOI: 10.1023/A:1025329323438 |
0.679 |
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| 2002 |
Song HJ, Billeter JC, Reynaud E, Carlo T, Spana EP, Perrimon N, Goodwin SF, Baker BS, Taylor BJ. The fruitless gene is required for the proper formation of axonal tracts in the embryonic central nervous system of Drosophila. Genetics. 162: 1703-24. PMID 12524343 |
0.706 |
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| 2002 |
Hou SX, Zheng Z, Chen X, Perrimon N. The Jak/STAT pathway in model organisms: emerging roles in cell movement. Developmental Cell. 3: 765-78. PMID 12479803 DOI: 10.1016/S1534-5807(02)00376-3 |
0.384 |
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| 2002 |
Wills Z, Emerson M, Rusch J, Bikoff J, Baum B, Perrimon N, Van Vactor D. A Drosophila homolog of cyclase-associated proteins collaborates with the Abl tyrosine kinase to control midline axon pathfinding. Neuron. 36: 611-22. PMID 12441051 DOI: 10.1016/S0896-6273(02)01022-X |
0.361 |
|
| 2002 |
Boutros M, Agaisse H, Perrimon N. Sequential activation of signaling pathways during innate immune responses in Drosophila. Developmental Cell. 3: 711-22. PMID 12431377 DOI: 10.1016/S1534-5807(02)00325-8 |
0.347 |
|
| 2002 |
Nybakken K, Perrimon N. Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila. Biochimica Et Biophysica Acta. 1573: 280-91. PMID 12417410 DOI: 10.1016/S0304-4165(02)00395-1 |
0.35 |
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| 2002 |
Hrdlicka L, Gibson M, Kiger A, Micchelli C, Schober M, Schöck F, Perrimon N. Analysis of twenty-four Gal4 lines in Drosophila melanogaster. Genesis (New York, N.Y. : 2000). 34: 51-7. PMID 12324947 DOI: 10.1002/Gene.10125 |
0.786 |
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| 2002 |
Schober M, Perrimon N. Unconventional ways to travel. Nature Cell Biology. 4: E211-2. PMID 12205482 DOI: 10.1038/ncb0902-e211 |
0.346 |
|
| 2002 |
Nybakken K, Perrimon N. Hedgehog signal transduction: recent findings. Current Opinion in Genetics & Development. 12: 503-11. PMID 12200154 DOI: 10.1016/S0959-437X(02)00333-7 |
0.361 |
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| 2002 |
Li WX, Agaisse H, Mathey-Prevot B, Perrimon N. Differential requirement for STAT by gain-of-function and wild-type receptor tyrosine kinase Torso in Drosophila. Development (Cambridge, England). 129: 4241-8. PMID 12183376 |
0.658 |
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| 2002 |
Schock F, Perrimon N. Molecular mechanisms of epithelial morphogenesis. Annual Review of Cell and Developmental Biology. 18: 463-93. PMID 12142280 DOI: 10.1146/annurev.cellbio.18.022602.131838 |
0.706 |
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| 2002 |
Moon RT, Bowerman B, Boutros M, Perrimon N. The promise and perils of Wnt signaling through beta-catenin. Science (New York, N.Y.). 296: 1644-6. PMID 12040179 DOI: 10.1126/science.1071549 |
0.348 |
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| 2002 |
Mathew D, Gramates LS, Packard M, Thomas U, Bilder D, Perrimon N, Gorczyca M, Budnik V. Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein. Current Biology : Cb. 12: 531-9. PMID 11937021 DOI: 10.1016/S0960-9822(02)00758-3 |
0.593 |
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| 2002 |
Chen HW, Marinissen MJ, Oh SW, Chen X, Melnick M, Perrimon N, Gutkind JS, Hou SX. CKA, a novel multidomain protein, regulates the JUN N-terminal kinase signal transduction pathway in Drosophila. Molecular and Cellular Biology. 22: 1792-803. PMID 11865058 DOI: 10.1128/MCB.22.6.1792-1803.2002 |
0.385 |
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| 2002 |
Micchelli CA, The I, Selva E, Mogila V, Perrimon N. Rasp, a putative transmembrane acyltransferase, is required for Hedgehog signaling. Development (Cambridge, England). 129: 843-51. PMID 11861468 |
0.59 |
|
| 2002 |
Stronach B, Perrimon N. Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper. Genes & Development. 16: 377-87. PMID 11825878 DOI: 10.1101/Gad.953002 |
0.744 |
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| 2002 |
Ghiglione C, Bach EA, Paraiso Y, Carraway KL, Noselli S, Perrimon N. Mechanism of activation of the Drosophila EGF Receptor by the TGFalpha ligand Gurken during oogenesis. Development (Cambridge, England). 129: 175-86. PMID 11782411 |
0.526 |
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| 2001 |
Hong Y, Stronach B, Perrimon N, Jan LY, Jan YN. Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts. Nature. 414: 634-8. PMID 11740559 DOI: 10.1038/414634A |
0.74 |
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| 2001 |
Selva EM, Perrimon N. Role of heparan sulfate proteoglycans in cell signaling and cancer. Advances in Cancer Research. 83: 67-80. PMID 11665721 DOI: 10.1016/S0065-230X(01)83003-7 |
0.376 |
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| 2001 |
Baum B, Perrimon N. Spatial control of the actin cytoskeleton in Drosophila epithelial cells. Nature Cell Biology. 3: 883-90. PMID 11584269 DOI: 10.1038/ncb1001-883 |
0.329 |
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| 2001 |
Suzanne M, Perrimon N, Noselli S. The Drosophila JNK pathway controls the morphogenesis of the egg dorsal appendages and micropyle. Developmental Biology. 237: 282-94. PMID 11543614 DOI: 10.1006/dbio.2001.0384 |
0.391 |
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| 2001 |
Selva EM, Hong K, Baeg GH, Beverley SM, Turco SJ, Perrimon N, Häcker U. Dual role of the fringe connection gene in both heparan sulphate and fringe-dependent signalling events. Nature Cell Biology. 3: 809-15. PMID 11533660 DOI: 10.1038/Ncb0901-809 |
0.66 |
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| 2001 |
Stronach BE, Perrimon N. Investigation of leading edge formation at the interface of amnioserosa and dorsal ectoderm in the Drosophila embryo. Development (Cambridge, England). 128: 2905-13. PMID 11532914 |
0.727 |
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| 2001 |
Vincent S, Perkins LA, Perrimon N. Doublesex surprises. Cell. 106: 399-402. PMID 11525726 DOI: 10.1016/S0092-8674(01)00468-8 |
0.526 |
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| 2001 |
Vincent S, Perrimon N. Developmental biology. Fishing for morphogens. Nature. 411: 533, 535-6. PMID 11385549 DOI: 10.1038/35079214 |
0.627 |
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| 2001 |
Baeg GH, Lin X, Khare N, Baumgartner S, Perrimon N. Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless. Development (Cambridge, England). 128: 87-94. PMID 11092814 DOI: 10.1042/Bst029A010C |
0.394 |
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| 2001 |
Bilder D, Birnbaum D, Borg J, Huibregtse J, Kennedy M, Labouesse M, Mechler B, Perrimon N. Response to “Problems with LAP nomenclature” Nature Cell Biology. 3: E90-E90. DOI: 10.1038/35070149 |
0.561 |
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| 2000 |
Noselli S, Perrimon N. Signal transduction. Are there close encounters between signaling pathways? Science (New York, N.Y.). 290: 68-9. PMID 11183153 DOI: 10.1126/SCIENCE.290.5489.68 |
0.364 |
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| 2000 |
Zeidler MP, Perrimon N, Strutt DI. Multiple roles for four-jointed in planar polarity and limb patterning. Developmental Biology. 228: 181-96. PMID 11112323 DOI: 10.1006/dbio.2000.9940 |
0.331 |
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| 2000 |
Noll E, Medina M, Hartley D, Zhou J, Perrimon N, Kosik KS. Presenilin affects arm/beta-catenin localization and function in Drosophila. Developmental Biology. 227: 450-64. PMID 11071766 DOI: 10.1006/dbio.2000.9925 |
0.335 |
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| 2000 |
Zeidler MP, Perrimon N. Sex determination: co-opted signals determine gender. Current Biology : Cb. 10: R682-4. PMID 10996811 DOI: 10.1016/S0960-9822(00)00686-2 |
0.323 |
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| 2000 |
Baum B, Li W, Perrimon N. A cyclase-associated protein regulates actin and cell polarity during Drosophila oogenesis and in yeast. Current Biology : Cb. 10: 964-73. PMID 10985383 DOI: 10.1016/S0960-9822(00)00640-0 |
0.684 |
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| 2000 |
Baeg GH, Perrimon N. Functional binding of secreted molecules to heparan sulfate proteoglycans in Drosophila. Current Opinion in Cell Biology. 12: 575-80. PMID 10978892 DOI: 10.1016/S0955-0674(00)00134-4 |
0.352 |
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| 2000 |
Lin X, Perrimon N. Role of heparan sulfate proteoglycans in cell-cell signaling in Drosophila. Matrix Biology : Journal of the International Society For Matrix Biology. 19: 303-7. PMID 10963990 DOI: 10.1016/S0945-053X(00)00073-1 |
0.38 |
|
| 2000 |
Bilder D, Li M, Perrimon N. Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science (New York, N.Y.). 289: 113-6. PMID 10884224 DOI: 10.1126/science.289.5476.113 |
0.641 |
|
| 2000 |
Bilder D, Birnbaum D, Borg JP, Bryant P, Huigbretse J, Jansen E, Kennedy MB, Labouesse M, Legouis R, Mechler B, Perrimon N, Petit M, Sinha P. Collective nomenclature for LAP proteins. Nature Cell Biology. 2: E114. PMID 10878817 DOI: 10.1038/35017119 |
0.583 |
|
| 2000 |
Tanaka K, Okabayashi K, Asashima M, Perrimon N, Kadowaki T. The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. European Journal of Biochemistry / Febs. 267: 4300-11. PMID 10866835 DOI: 10.1046/J.1432-1033.2000.01478.X |
0.365 |
|
| 2000 |
Zeidler MP, Bach EA, Perrimon N. The roles of the Drosophila JAK/STAT pathway. Oncogene. 19: 2598-606. PMID 10851058 DOI: 10.1038/sj.onc.1203482 |
0.626 |
|
| 2000 |
The I, Perrimon N. Morphogen diffusion: the case of the wingless protein. Nature Cell Biology. 2: E79-82. PMID 10806491 DOI: 10.1038/35010511 |
0.305 |
|
| 2000 |
Perrimon N, Bernfield M. Specificities of heparan sulphate proteoglycans in developmental processes. Nature. 404: 725-8. PMID 10783877 DOI: 10.1038/35008000 |
0.353 |
|
| 2000 |
Bilder D, Perrimon N. Localization of apical epithelial determinants by the basolateral PDZ protein Scribble. Nature. 403: 676-80. PMID 10688207 DOI: 10.1038/35001108 |
0.631 |
|
| 1999 |
Zeidler MP, Perrimon N, Strutt DI. The four-jointed gene is required in the Drosophila eye for ommatidial polarity specification. Current Biology : Cb. 9: 1363-72. PMID 10607560 DOI: 10.1016/S0960-9822(00)80081-0 |
0.348 |
|
| 1999 |
Stronach BE, Perrimon N. Stress signaling in Drosophila. Oncogene. 18: 6172-82. PMID 10557109 DOI: 10.1038/Sj.Onc.1203125 |
0.75 |
|
| 1999 |
The I, Bellaiche Y, Perrimon N. Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan. Molecular Cell. 4: 633-9. PMID 10549295 DOI: 10.1016/S1097-2765(00)80214-2 |
0.672 |
|
| 1999 |
Spana E, Perrimon N. The latest in signal transduction, 1999. Specificity in Signal Transduction, Keystone, Colorado, USA, 9-14 April 1999. Trends in Genetics : Tig. 15: 301-2. PMID 10475855 DOI: 10.1016/S0168-9525(99)01791-6 |
0.718 |
|
| 1999 |
Mogila VA, Bellaiche Y, Perrimon N. Expression of I-Sce I in Drosophila to induce DNA double-strand breaks. Methods in Molecular Biology (Clifton, N.J.). 113: 439-45. PMID 10443440 DOI: 10.1385/1-59259-675-4:439 |
0.596 |
|
| 1999 |
Lin X, Perrimon N. Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling. Nature. 400: 281-4. PMID 10421372 DOI: 10.1038/22343 |
0.674 |
|
| 1999 |
Bellaiche Y, Mogila V, Perrimon N. I-SceI endonuclease, a new tool for studying DNA double-strand break repair mechanisms in Drosophila. Genetics. 152: 1037-44. PMID 10388822 |
0.618 |
|
| 1999 |
Zeidler MP, Perrimon N, Strutt DI. Polarity determination in the Drosophila eye: a novel role for unpaired and JAK/STAT signaling. Genes & Development. 13: 1342-53. PMID 10346822 DOI: 10.1101/Gad.13.10.1342 |
0.317 |
|
| 1999 |
Perrimon N, McMahon AP. Negative feedback mechanisms and their roles during pattern formation. Cell. 97: 13-6. PMID 10199398 DOI: 10.1016/S0092-8674(00)80710-2 |
0.368 |
|
| 1999 |
Ghiglione C, Perrimon N, Perkins LA. Quantitative variations in the level of MAPK activity control patterning of the embryonic termini in Drosophila. Developmental Biology. 205: 181-93. PMID 9882506 DOI: 10.1006/Dbio.1998.9102 |
0.38 |
|
| 1998 |
Cleghon V, Feldmann P, Ghiglione C, Copeland TD, Perrimon N, Hughes DA, Morrison DK. Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway. Molecular Cell. 2: 719-27. PMID 9885560 DOI: 10.1016/S1097-2765(00)80287-7 |
0.344 |
|
| 1998 |
Shulman JM, Perrimon N, Axelrod JD. Frizzled signaling and the developmental control of cell polarity. Trends in Genetics : Tig. 14: 452-8. PMID 9825673 DOI: 10.1016/S0168-9525(98)01584-4 |
0.708 |
|
| 1998 |
Perrimon N, Duffy JB. Developmental biology. Sending all the right signals. Nature. 396: 18-9. PMID 9817197 DOI: 10.1038/23815 |
0.309 |
|
| 1998 |
Harrison DA, McCoon PE, Binari R, Gilman M, Perrimon N. Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway. Genes & Development. 12: 3252-63. PMID 9784499 DOI: 10.1101/Gad.12.20.3252 |
0.614 |
|
| 1998 |
Axelrod JD, Miller JR, Shulman JM, Moon RT, Perrimon N. Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes & Development. 12: 2610-22. PMID 9716412 DOI: 10.1101/Gad.12.16.2610 |
0.7 |
|
| 1998 |
Perrimon N. New advances in Drosophila provide opportunities to study gene functions. Proceedings of the National Academy of Sciences of the United States of America. 95: 9716-7. PMID 9707540 DOI: 10.1073/Pnas.95.17.9716 |
0.383 |
|
| 1998 |
Bellaiche Y, The I, Perrimon N. Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion. Nature. 394: 85-8. PMID 9665133 DOI: 10.1038/27932 |
0.633 |
|
| 1998 |
Perrimon N. Creating mosaics in Drosophila. The International Journal of Developmental Biology. 42: 243-7. PMID 9654004 DOI: 10.1387/Ijdb.9654004 |
0.353 |
|
| 1998 |
Duffy JB, Harrison DA, Perrimon N. Identifying loci required for follicular patterning using directed mosaics. Development (Cambridge, England). 125: 2263-71. PMID 9584125 |
0.584 |
|
| 1998 |
Mathey-Prevot B, Perrimon N. Mammalian and Drosophila blood: JAK of all trades? Cell. 92: 697-700. PMID 9529244 DOI: 10.1016/S0092-8674(00)81396-3 |
0.322 |
|
| 1998 |
Häcker U, Perrimon N. DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila. Genes & Development. 12: 274-84. PMID 9436986 DOI: 10.1101/Gad.12.2.274 |
0.681 |
|
| 1997 |
Riesgo-Escovar JR, Hafen E, Hou XS, Goldstein ES, Perrimon N, Glise B, Noselli S, Kockel L, Zeitlinger J, Staszewski LM, Mlodzik M, Bohmann D. Connecting up the pathways in Drosophila development. Trends in Cell Biology. 7: 421-2. PMID 17708993 DOI: 10.1016/S0962-8924(97)88135-4 |
0.632 |
|
| 1997 |
Goode S, Perrimon N. Brainiac and fringe are similar pioneer proteins that impart specificity to notch signaling during Drosophila development. Cold Spring Harbor Symposia On Quantitative Biology. 62: 177-84. PMID 9598350 DOI: 10.1101/Sqb.1997.062.01.023 |
0.344 |
|
| 1997 |
Eberl DF, Duyk GM, Perrimon N. A genetic screen for mutations that disrupt an auditory response in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 94: 14837-42. PMID 9405700 DOI: 10.1073/pnas.94.26.14837 |
0.639 |
|
| 1997 |
Häcker U, Lin X, Perrimon N. The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis. Development (Cambridge, England). 124: 3565-73. PMID 9342049 |
0.652 |
|
| 1997 |
Goode S, Perrimon N. Inhibition of patterned cell shape change and cell invasion by Discs large during Drosophila oogenesis. Genes & Development. 11: 2532-44. PMID 9334318 DOI: 10.1101/Gad.11.19.2532 |
0.391 |
|
| 1997 |
Engstrom L, Noll E, Perrimon N. Paradigms to study signal transduction pathways in Drosophila. Current Topics in Developmental Biology. 35: 229-61. PMID 9292272 DOI: 10.1016/S0070-2153(08)60261-6 |
0.413 |
|
| 1997 |
Hou XS, Goldstein ES, Perrimon N. Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway to the Decapentaplegic signal transduction pathway in regulating epithelial cell sheet movement. Genes & Development. 11: 1728-37. PMID 9224721 DOI: 10.1101/Gad.11.13.1728 |
0.388 |
|
| 1997 |
Eberl DF, Lorenz LJ, Melnick MB, Sood V, Lasko P, Perrimon N. A new enhancer of position-effect variegation in Drosophila melanogaster encodes a putative RNA helicase that binds chromosomes and is regulated by the cell cycle. Genetics. 146: 951-63. PMID 9215899 |
0.656 |
|
| 1997 |
Li W, Perrimon N. Specificity of receptor tyrosine kinase signaling pathways: lessons from Drosophila. Genetic Engineering. 19: 167-82. PMID 9193108 DOI: 10.1007/978-1-4615-5925-2_9 |
0.695 |
|
| 1997 |
Perrimon N, Perkins LA. There must be 50 ways to rule the signal: the case of the Drosophila EGF receptor. Cell. 89: 13-6. PMID 9094709 DOI: 10.1016/S0092-8674(00)80177-4 |
0.347 |
|
| 1997 |
Yu Y, Li W, Su K, Yussa M, Han W, Perrimon N, Pick L. The nuclear hormone receptor Ftz-F1 is a cofactor for the Drosophila homeodomain protein Ftz. Nature. 385: 552-5. PMID 9020364 DOI: 10.1038/385552A0 |
0.669 |
|
| 1996 |
Kadowaki T, Wilder E, Klingensmith J, Zachary K, Perrimon N. The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing. Genes & Development. 10: 3116-28. PMID 8985181 DOI: 10.1101/Gad.10.24.3116 |
0.701 |
|
| 1996 |
Perkins LA, Johnson MR, Melnick MB, Perrimon N. The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila. Developmental Biology. 180: 63-81. PMID 8948575 DOI: 10.1006/Dbio.1996.0285 |
0.334 |
|
| 1996 |
Rulifson EJ, Micchelli CA, Axelrod JD, Perrimon N, Blair SS. wingless refines its own expression domain on the Drosophila wing margin. Nature. 384: 72-4. PMID 8900280 DOI: 10.1038/384072A0 |
0.767 |
|
| 1996 |
Klingensmith J, Yang Y, Axelrod JD, Beier DR, Perrimon N, Sussman DJ. Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2. Mechanisms of Development. 58: 15-26. PMID 8887313 DOI: 10.1016/S0925-4773(96)00549-7 |
0.803 |
|
| 1996 |
Musacchio M, Perrimon N. The Drosophila kekkon genes: novel members of both the leucine-rich repeat and immunoglobulin superfamilies expressed in the CNS. Developmental Biology. 178: 63-76. PMID 8812109 DOI: 10.1006/dbio.1996.0198 |
0.397 |
|
| 1996 |
Duffy JB, Perrimon N. Recent advances in understanding signal transduction pathways in worms and flies. Current Opinion in Cell Biology. 8: 231-8. PMID 8791421 DOI: 10.1016/S0955-0674(96)80070-6 |
0.365 |
|
| 1996 |
Perrimon N. Serpentine proteins slither into the wingless and hedgehog fields. Cell. 86: 513-6. PMID 8752205 DOI: 10.1016/S0092-8674(00)80124-5 |
0.323 |
|
| 1996 |
Hou XS, Melnick MB, Perrimon N. Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs. Cell. 84: 411-9. PMID 8608595 DOI: 10.1016/S0092-8674(00)81286-6 |
0.354 |
|
| 1996 |
Cleghon V, Gayko U, Copeland TD, Perkins LA, Perrimon N, Morrison DK. Drosophila terminal structure development is regulated by the compensatory activities of positive and negative phosphotyrosine signaling sites on the Torso RTK. Genes & Development. 10: 566-77. PMID 8598287 DOI: 10.1101/Gad.10.5.566 |
0.343 |
|
| 1996 |
Axelrod JD, Matsuno K, Artavanis-Tsakonas S, Perrimon N. Interaction between Wingless and Notch signaling pathways mediated by dishevelled. Science (New York, N.Y.). 271: 1826-32. PMID 8596950 DOI: 10.1126/Science.271.5257.1826 |
0.702 |
|
| 1996 |
Rulifson EJ, Micchelli CA, Axelrod JD, Perrimon N, Blair SS. Erratum: wingless refines its own expression domain on the Drosophila wing margin Nature. 384: 597-597. DOI: 10.1038/384597a0 |
0.631 |
|
| 1995 |
Perrimon N, Lu X, Hou XS, Hsu JC, Melnick MB, Chou TB, Perkins LA. Dissection of the Torso signal transduction pathway in Drosophila. Molecular Reproduction and Development. 42: 515-22. PMID 8607984 DOI: 10.1002/Mrd.1080420421 |
0.365 |
|
| 1995 |
Manoukian AS, Yoffe KB, Wilder EL, Perrimon N. The porcupine gene is required for wingless autoregulation in Drosophila. Development (Cambridge, England). 121: 4037-44. PMID 8575304 |
0.301 |
|
| 1995 |
Harrison DA, Binari R, Nahreini TS, Gilman M, Perrimon N. Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. The Embo Journal. 14: 2857-65. PMID 7796812 DOI: 10.1002/J.1460-2075.1995.Tb07285.X |
0.563 |
|
| 1995 |
Yin JC, Wallach JS, Wilder EL, Klingensmith J, Dang D, Perrimon N, Zhou H, Tully T, Quinn WG. A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist. Molecular and Cellular Biology. 15: 5123-30. PMID 7651429 DOI: 10.1128/Mcb.15.9.5123 |
0.684 |
|
| 1995 |
Yoffe KB, Manoukian AS, Wilder EL, Brand AH, Perrimon N. Evidence for engrailed-independent wingless autoregulation in Drosophila. Developmental Biology. 170: 636-50. PMID 7649390 DOI: 10.1006/Dbio.1995.1243 |
0.602 |
|
| 1995 |
Rivera-Pomar R, Lu X, Perrimon N, Taubert H, Jäckle H. Activation of posterior gap gene expression in the Drosophila blastoderm. Nature. 376: 253-6. PMID 7617036 DOI: 10.1038/376253a0 |
0.326 |
|
| 1994 |
Binari R, Perrimon N. Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila. Genes & Development. 8: 300-12. PMID 8314084 DOI: 10.1101/GAD.8.3.300 |
0.337 |
|
| 1994 |
Klingensmith J, Nusse R, Perrimon N. The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal Genes and Development. 8: 118-130. PMID 8288125 DOI: 10.1101/Gad.8.1.118 |
0.725 |
|
| 1994 |
Siegfried E, Wilder EL, Perrimon N. Components of wingless signalling in Drosophila. Nature. 367: 76-80. PMID 8107779 DOI: 10.1038/367076a0 |
0.422 |
|
| 1994 |
Siegfried E, Perrimon N. Drosophila wingless: a paradigm for the function and mechanism of Wnt signaling. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 16: 395-404. PMID 8080429 DOI: 10.1002/bies.950160607 |
0.424 |
|
| 1994 |
Perrimon N. Signalling pathways initiated by receptor protein tyrosine kinases in Drosophila. Current Opinion in Cell Biology. 6: 260-6. PMID 8024818 DOI: 10.1016/0955-0674(94)90145-7 |
0.339 |
|
| 1994 |
Sussman DJ, Klingensmith J, Salinas P, Adams PS, Nusse R, Perrimon N. Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled Developmental Biology. 166: 73-86. PMID 7958461 DOI: 10.1006/Dbio.1994.1297 |
0.705 |
|
| 1994 |
Brand AH, Perrimon N. Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis. Genes & Development. 8: 629-39. PMID 7926754 DOI: 10.1101/Gad.8.5.629 |
0.593 |
|
| 1994 |
Perrimon N. The genetic basis of patterned baldness in Drosophila. Cell. 76: 781-4. PMID 7907277 DOI: 10.1016/0092-8674(94)90351-4 |
0.412 |
|
| 1994 |
Perrimon N, Desplan C. Signal transduction in the early Drosophila embryo: when genetics meets biochemistry. Trends in Biochemical Sciences. 19: 509-13. PMID 7855897 DOI: 10.1016/0968-0004(94)90140-6 |
0.342 |
|
| 1994 |
Duffy JB, Perrimon N. The Torso pathway in Drosophila: Lessons on receptor tyrosine kinase signaling and pattern formation Developmental Biology. 166: 380-395. PMID 7813764 DOI: 10.1006/dbio.1994.1324 |
0.343 |
|
| 1994 |
Brand AH, Manoukian AS, Perrimon N. Ectopic expression in Drosophila. Methods in Cell Biology. 44: 635-54. PMID 7707973 DOI: 10.1016/S0091-679X(08)60936-X |
0.572 |
|
| 1993 |
Harrison DA, Perrimon N. Simple and efficient generation of marked clones in Drosophila. Current Biology : Cb. 3: 424-33. PMID 15335709 DOI: 10.1016/0960-9822(93)90349-S |
0.6 |
|
| 1993 |
Lu X, Chou TB, Williams NG, Roberts T, Perrimon N. Control of cell fate determination by p21ras/Ras1, an essential component of torso signaling in Drosophila. Genes & Development. 7: 621-32. PMID 8458578 DOI: 10.1101/Gad.7.4.621 |
0.382 |
|
| 1993 |
Perrimon N. The torso receptor protein-tyrosine kinase signaling pathway: an endless story. Cell. 74: 219-22. PMID 8343949 DOI: 10.1016/0092-8674(93)90412-J |
0.355 |
|
| 1993 |
Noll E, Perkins LA, Mahowald AP, Perrimon N. Approaches to identify genes involved in Drosophila embryonic CNS development. Journal of Neurobiology. 24: 701-22. PMID 8331336 DOI: 10.1002/Neu.480240603 |
0.595 |
|
| 1993 |
Van Heuvel MD, Harryman-Samos C, Klingensmith J, Perrimon N, Nusse R. Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein Embo Journal. 12: 5293-5302. PMID 8262072 DOI: 10.1002/J.1460-2075.1993.Tb06225.X |
0.691 |
|
| 1993 |
Brand AH, Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development (Cambridge, England). 118: 401-15. PMID 8223268 |
0.595 |
|
| 1993 |
Dang DT, Perrimon N. Use of a yeast site-specific recombinase to generate embryonic mosaics in Drosophila. Developmental Genetics. 13: 367-75. PMID 1292893 DOI: 10.1002/DVG.1020130507 |
0.323 |
|
| 1992 |
Rutledge BJ, Zhang K, Bier E, Jan YN, Perrimon N. The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis. Genes & Development. 6: 1503-17. PMID 1644292 DOI: 10.1101/GAD.6.8.1503 |
0.376 |
|
| 1992 |
Perkins LA, Larsen I, Perrimon N. corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso. Cell. 70: 225-36. PMID 1638629 DOI: 10.1016/0092-8674(92)90098-W |
0.369 |
|
| 1992 |
Eberl DF, Perkins LA, Engelstein M, Hilliker AJ, Perrimon N. Genetic and developmental analysis of polytene section 17 of the X chromosome of Drosophila melanogaster. Genetics. 130: 569-83. PMID 1551578 |
0.636 |
|
| 1992 |
Siegfried E, Chou TB, Perrimon N. wingless signaling acts through zeste-white 3, the Drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate. Cell. 71: 1167-79. PMID 1335365 DOI: 10.1016/S0092-8674(05)80065-0 |
0.412 |
|
| 1991 |
Zhang K, Smouse D, Perrimon N. The crooked neck gene of Drosophila contains a motif found in a family of yeast cell cycle genes. Genes & Development. 5: 1080-91. PMID 2044955 DOI: 10.1101/GAD.5.6.1080 |
0.371 |
|
| 1991 |
Perrimon N, Noll E, McCall K, Brand A. Generating lineage-specific markers to study Drosophila development Developmental Genetics. 12: 238-252. PMID 1651183 DOI: 10.1002/Dvg.1020120309 |
0.58 |
|
| 1990 |
Smouse D, Perrimon N. Genetic dissection of a complex neurological mutant, polyhomeotic, in Drosophila. Developmental Biology. 139: 169-85. PMID 2328834 DOI: 10.1016/0012-1606(90)90286-R |
0.321 |
|
| 1990 |
Siegfried E, Ambrosio L, Perrimon N. Serine/threonine protein kinases in Drosophila. Trends in Genetics : Tig. 6: 357-62. PMID 2150900 DOI: 10.1016/0168-9525(90)90277-D |
0.3 |
|
| 1990 |
Siegfried E, Perkins LA, Capaci TM, Perrimon N. Putative protein kinase product of the Drosophila segment-polarity gene zeste-white3. Nature. 345: 825-9. PMID 2113617 DOI: 10.1038/345825A0 |
0.347 |
|
| 1990 |
Perkins LA, Doctor JS, Zhang K, Stinson L, Perrimon N, Craig EA. Molecular and developmental characterization of the heat shock cognate 4 gene of Drosophila melanogaster. Molecular and Cellular Biology. 10: 3232-8. PMID 2111451 DOI: 10.1128/Mcb.10.6.3232 |
0.323 |
|
| 1990 |
Finkelstein R, Smouse D, Capaci TM, Spradling AC, Perrimon N. The orthodenticle gene encodes a novel homeo domain protein involved in the development of the Drosophila nervous system and ocellar visual structures. Genes & Development. 4: 1516-27. PMID 1979296 DOI: 10.1101/Gad.4.9.1516 |
0.591 |
|
| 1990 |
Finkelstein R, Perrimon N. The orthodenticle gene is regulated by bicoid and torso and specifies Drosophila head development. Nature. 346: 485-8. PMID 1974036 DOI: 10.1038/346485A0 |
0.345 |
|
| 1990 |
Zhang K, Chaillet JR, Perkins LA, Halazonetis TD, Perrimon N. Drosophila homolog of the mammalian jun oncogene is expressed during embryonic development and activates transcription in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 6281-5. PMID 1696724 DOI: 10.1073/Pnas.87.16.6281 |
0.396 |
|
| 1989 |
Klingensmith J, Noll E, Perrimon N. The segment polarity phenotype of Drosophila involves differential tendencies toward transformation and cell death Developmental Biology. 134: 130-145. PMID 2731645 DOI: 10.1016/0012-1606(89)90084-5 |
0.689 |
|
| 1989 |
Perrimon N, Smouse D. Multiple functions of a Drosophila homeotic gene, zeste-white 3, during segmentation and neurogenesis. Developmental Biology. 135: 287-305. PMID 2570722 DOI: 10.1016/0012-1606(89)90180-2 |
0.378 |
|
| 1989 |
Ambrosio L, Mahowald AP, Perrimon N. Requirement of the Drosophila raf homologue for torso function. Nature. 342: 288-91. PMID 2554148 DOI: 10.1038/342288a0 |
0.609 |
|
| 1988 |
Oliver B, Perrimon N, Mahowald AP. Genetic evidence that the sans fille locus is involved in Drosophila sex determination Genetics. 120: 159-171. PMID 3220249 |
0.618 |
|
| 1988 |
Smouse D, Goodman C, Mahowald A, Perrimon N. polyhomeotic: a gene required for the embryonic development of axon pathways in the central nervous system of Drosophila. Genes & Development. 2: 830-42. PMID 2905316 DOI: 10.1101/Gad.2.7.830 |
0.599 |
|
| 1987 |
Perrimon N, Mahowald AP. Multiple functions of segment polarity genes in Drosophila. Developmental Biology. 119: 587-600. PMID 3803719 DOI: 10.1016/0012-1606(87)90061-3 |
0.568 |
|
| 1987 |
Oliver B, Perrimon N, Mahowald AP. The ovo locus is required for sex-specific germ line maintenance in Drosophila Genes & Development. 1: 913-923. PMID 3428601 DOI: 10.1101/Gad.1.9.913 |
0.67 |
|
| 1987 |
Petschek JP, Perrimon N, Mahowald AP. Region-specific defects in l(1)giant embryos of Drosophila melanogaster. Developmental Biology. 119: 175-89. PMID 3098602 DOI: 10.1016/0012-1606(87)90219-3 |
0.564 |
|
| 1986 |
Degelmann A, Hardy PA, Perrimon N, Mahowald AP. Developmental analysis of the torso-like phenotype in Drosophila produced by a maternal-effect locus. Developmental Biology. 115: 479-89. PMID 3709971 DOI: 10.1016/0012-1606(86)90268-X |
0.62 |
|
| 1986 |
Perrimon N, Mahowald AP. l(1)hopscotch, A larval-pupal zygotic lethal with a specific maternal effect on segmentation in Drosophila. Developmental Biology. 118: 28-41. PMID 3095163 DOI: 10.1016/0012-1606(86)90070-9 |
0.565 |
|
| 1985 |
Mortin MA, Perrimon N, Bonner JJ. Clonal analysis of two mutations in the large subunit of RNA polymerase II of Drosophila. Molecular & General Genetics : Mgg. 199: 421-6. PMID 3929014 DOI: 10.1007/BF00330753 |
0.318 |
|
| 1985 |
Perrimon N, Engstrom L, Mahowald AP. A pupal lethal mutation with a paternally influenced maternal effect on embryonic development in Drosophila melanogaster. Developmental Biology. 110: 480-91. PMID 3926563 DOI: 10.1016/0012-1606(85)90105-8 |
0.603 |
|
| 1985 |
Konrad KD, Engstrom L, Perrimon N, Mahowald AP. Genetic analysis of oogenesis and the role of maternal gene expression in early development. Developmental Biology (New York, N.Y. : 1985). 1: 577-617. PMID 3917206 |
0.555 |
|
| 1984 |
Perrimon N, Engstrom L, Mahowald AP. The effects of zygotic lethal mutations on female germ-line functions in Drosophila. Developmental Biology. 105: 404-14. PMID 6479445 DOI: 10.1016/0012-1606(84)90297-5 |
0.595 |
|
| 1984 |
Perrimon N, Engstrom L, Mahowald AP. Developmental genetics of the 2E-F region of the Drosophila X chromosome: a region rich in "developmentally important" genes. Genetics. 108: 559-72. PMID 6437900 |
0.565 |
|
| 1983 |
Perrimon N, Gans M. Clonal analysis of the tissue specificity of recessive female-sterile mutations of Drosophila melanogaster using a dominant female-sterile mutation Fs(1)K1237. Developmental Biology. 100: 365-73. PMID 6418585 DOI: 10.1016/0012-1606(83)90231-2 |
0.593 |
|
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