Year |
Citation |
Score |
2024 |
Lin W, Phatarphekar A, Zhong Y, Liu L, Kwon HB, Gerwick WH, Wang Y, Mehta S, Zhang J. Light-gated integrator for highlighting kinase activity in living cells. Nature Communications. 15: 7804. PMID 39242543 DOI: 10.1038/s41467-024-51270-4 |
0.383 |
|
2024 |
Su Q, Zhang J, Lin W, Zhang JF, Newton AC, Mehta S, Yang J, Zhang J. Sensitive Fluorescent Biosensor Reveals Differential Subcellular Regulation of PKC. Biorxiv : the Preprint Server For Biology. PMID 38586003 DOI: 10.1101/2024.03.29.587373 |
0.344 |
|
2024 |
Lin W, Phatarphekar A, Zhong Y, Liu L, Kwon HB, Gerwick WH, Wang Y, Mehta S, Zhang J. Light-gated Integrator for Highlighting Kinase Activity in Living Cells. Biorxiv : the Preprint Server For Biology. PMID 38562887 DOI: 10.1101/2024.03.18.585554 |
0.392 |
|
2024 |
Hardy JC, Pool EH, Bruystens JGH, Zhou X, Li Q, Zhou DR, Palay M, Tan G, Chen L, Choi JLC, Lee HN, Strack S, Wang D, Taylor SS, Mehta S, et al. Molecular determinants and signaling effects of PKA RIα phase separation. Molecular Cell. PMID 38537638 DOI: 10.1016/j.molcel.2024.03.002 |
0.336 |
|
2023 |
Hardy JC, Pool EH, Bruystens JGH, Zhou X, Li Q, Zhou DR, Palay M, Tan G, Chen L, Choi JLC, Lee HN, Strack S, Wang D, Taylor SS, Mehta S, et al. Molecular Determinants and Signaling Effects of PKA RIα Phase Separation. Biorxiv : the Preprint Server For Biology. PMID 38168176 DOI: 10.1101/2023.12.10.570836 |
0.333 |
|
2023 |
Lyons AC, Mehta S, Zhang J. Fluorescent biosensors illuminate the spatial regulation of cell signaling across scales. The Biochemical Journal. 480: 1693-1717. PMID 37903110 DOI: 10.1042/BCJ20220223 |
0.38 |
|
2023 |
Posner C, Mehta S, Zhang J. Fluorescent biosensor imaging meets deterministic mathematical modelling: quantitative investigation of signalling compartmentalization. The Journal of Physiology. 601: 4227-4241. PMID 37747358 DOI: 10.1113/JP282696 |
0.369 |
|
2022 |
Schmitt DL, Mehta S, Zhang J. Study of spatiotemporal regulation of kinase signaling using genetically encodable molecular tools. Current Opinion in Chemical Biology. 71: 102224. PMID 36347198 DOI: 10.1016/j.cbpa.2022.102224 |
0.338 |
|
2022 |
Kwon Y, Mehta S, Clark M, Walters G, Zhong Y, Lee HN, Sunahara RK, Zhang J. Non-canonical β-adrenergic activation of ERK at endosomes. Nature. PMID 36289326 DOI: 10.1038/s41586-022-05343-3 |
0.354 |
|
2022 |
Schmitt DL, Curtis SD, Lyons AC, Zhang JF, Chen M, He CY, Mehta S, Shaw RJ, Zhang J. Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter. Nature Communications. 13: 3856. PMID 35790710 DOI: 10.1038/s41467-022-31190-x |
0.321 |
|
2022 |
Zhou X, Mehta S, Zhang J. AktAR and Akt-STOPS: Genetically Encodable Molecular Tools to Visualize and Perturb Akt Kinase Activity at Different Subcellular Locations in Living Cells. Current Protocols. 2: e416. PMID 35532280 DOI: 10.1002/cpz1.416 |
0.363 |
|
2022 |
Hardy JC, Mehta S, Zhang J. Measuring Spatiotemporal cAMP Dynamics Within an Endogenous Signaling Compartment Using FluoSTEP-ICUE. Methods in Molecular Biology (Clifton, N.J.). 2483: 351-366. PMID 35286687 DOI: 10.1007/978-1-0716-2245-2_22 |
0.361 |
|
2021 |
Su Q, Mehta S, Zhang J. Liquid-liquid phase separation: Orchestrating cell signaling through time and space. Molecular Cell. PMID 34619090 DOI: 10.1016/j.molcel.2021.09.010 |
0.332 |
|
2021 |
Keyes J, Mehta S, Zhang J. Strategies for Multiplexed Biosensor Imaging to Study Intracellular Signaling Networks. Methods in Molecular Biology (Clifton, N.J.). 2350: 1-20. PMID 34331275 DOI: 10.1007/978-1-0716-1593-5_1 |
0.37 |
|
2021 |
Tenner B, Zhang JZ, Kwon Y, Pessino V, Feng S, Huang B, Mehta S, Zhang J. FluoSTEPs: Fluorescent biosensors for monitoring compartmentalized signaling within endogenous microdomains. Science Advances. 7. PMID 34020947 DOI: 10.1126/sciadv.abe4091 |
0.396 |
|
2021 |
Mehta S, Zhang J. Biochemical Activity Architectures Visualized-Using Genetically Encoded Fluorescent Biosensors to Map the Spatial Boundaries of Signaling Compartments. Accounts of Chemical Research. PMID 33949851 DOI: 10.1021/acs.accounts.1c00056 |
0.414 |
|
2021 |
Zhang JF, Mehta S, Zhang J. Signaling Microdomains in the Spotlight: Visualizing Compartmentalized Signaling Using Genetically Encoded Fluorescent Biosensors. Annual Review of Pharmacology and Toxicology. 61: 587-608. PMID 33411579 DOI: 10.1146/annurev-pharmtox-010617-053137 |
0.402 |
|
2020 |
Zhang JF, Liu B, Hong I, Mo A, Roth RH, Tenner B, Lin W, Zhang JZ, Molina RS, Drobizhev M, Hughes TE, Tian L, Huganir RL, Mehta S, Zhang J. An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice. Nature Chemical Biology. PMID 32989297 DOI: 10.1038/s41589-020-00660-y |
0.378 |
|
2020 |
Zhang JZ, Lu TW, Stolerman LM, Tenner B, Yang JR, Zhang JF, Falcke M, Rangamani P, Taylor SS, Mehta S, Zhang J. Phase Separation of a PKA Regulatory Subunit Controls cAMP Compartmentation and Oncogenic Signaling. Cell. PMID 32846158 DOI: 10.1016/J.Cell.2020.07.043 |
0.451 |
|
2020 |
Zhou X, Mehta S, Zhang J. Genetically Encodable Fluorescent and Bioluminescent Biosensors Light Up Signaling Networks. Trends in Biochemical Sciences. PMID 32660810 DOI: 10.1016/J.Tibs.2020.06.001 |
0.437 |
|
2020 |
Lee HN, Mehta S, Zhang J. Recent advances in the use of genetically encodable optical tools to elicit and monitor signaling events. Current Opinion in Cell Biology. 63: 114-124. PMID 32058267 DOI: 10.1016/J.Ceb.2020.01.007 |
0.466 |
|
2020 |
Schmitt DL, Mehta S, Zhang J. Illuminating the kinome: Visualizing real-time kinase activity in biological systems using genetically encoded fluorescent protein-based biosensors. Current Opinion in Chemical Biology. 54: 63-69. PMID 31911398 DOI: 10.1016/J.Cbpa.2019.11.005 |
0.402 |
|
2020 |
Mehta S, Zhang J, Liu B, Hong I, Tenner B, Lin W, Huganir RL, Zhang J. An Ultrasensitive Fluorescent Biosensor for Multi‐modal Kinase Activity Detection and High‐resolution Imaging in Awake Mice The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04082 |
0.325 |
|
2020 |
Zhang JZ, Lu T, Tenner B, Yang J, Zhang J, Taylor S, Mehta S, Zhang J. PKA RIα phase separation drives cAMP compartmentation and suppresses tumorigenic signaling The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03204 |
0.353 |
|
2020 |
Schmitt DL, Zhang J, Chen M, Leung A, He CY, Curtis SD, Mehta S, Shaw RJ, Rangamani P, Zhang J. Illuminating Spatiotemporal Regulation of AMPK with a Genetically Encoded Excitation‐Ratiometric Biosensor for AMPK The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03063 |
0.328 |
|
2019 |
Hertel F, Li S, Chen M, Pott L, Mehta S, Zhang J. Fluorescent biosensors for multiplexed imaging of phosphoinositide dynamics. Acs Chemical Biology. PMID 31855412 DOI: 10.1021/Acschembio.9B00691 |
0.407 |
|
2019 |
Lin W, Mehta S, Zhang J. Genetically encoded fluorescent biosensors illuminate kinase signaling in cancer. The Journal of Biological Chemistry. PMID 31434714 DOI: 10.1074/Jbc.Rev119.006177 |
0.468 |
|
2019 |
Qian Y, Piatkevich KD, Mc Larney B, Abdelfattah AS, Mehta S, Murdock MH, Gottschalk S, Molina RS, Zhang W, Chen Y, Wu J, Drobizhev M, Hughes TE, Zhang J, Schreiter ER, et al. A genetically encoded near-infrared fluorescent calcium ion indicator. Nature Methods. PMID 30664778 DOI: 10.1038/S41592-018-0294-6 |
0.304 |
|
2018 |
Greenwald EC, Mehta S, Zhang J. Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks. Chemical Reviews. PMID 30550275 DOI: 10.1021/Acs.Chemrev.8B00333 |
0.458 |
|
2018 |
Mehta S, Zhang Y, Roth RH, Zhang JF, Mo A, Tenner B, Huganir RL, Zhang J. Single-fluorophore biosensors for sensitive and multiplexed detection of signalling activities. Nature Cell Biology. 20: 1215-1225. PMID 30250062 DOI: 10.1038/S41556-018-0200-6 |
0.455 |
|
2018 |
Grimsey NJ, Narala R, Rada CC, Mehta S, Stephens BS, Kufareva I, Lapek J, Gonzalez DJ, Handel TM, Zhang J, Trejo J. A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling. Cell Reports. 24: 3312-3323.e5. PMID 30232011 DOI: 10.1016/J.Celrep.2018.08.061 |
0.38 |
|
2017 |
Nygren PJ, Mehta S, Schweppe DK, Langeberg LK, Whiting JL, Weisbrod CR, Bruce JE, Zhang J, Veesler D, Scott JD. Intrinsic disorder within AKAP79 fine-tunes anchored phosphatase activity toward substrates and drug sensitivity. Elife. 6. PMID 28967377 DOI: 10.7554/Elife.30872 |
0.327 |
|
2017 |
Mehta S, Zhang J. Illuminating the cell's biochemical activity architecture. Biochemistry. PMID 28718621 DOI: 10.1021/Acs.Biochem.7B00561 |
0.394 |
|
2017 |
Ni Q, Mehta S, Zhang J. Live-cell imaging of cell signaling using genetically encoded fluorescent reporters. The Febs Journal. PMID 28613457 DOI: 10.1111/Febs.14134 |
0.467 |
|
2017 |
Gorshkov K, Mehta S, Ramamurthy S, Ronnett GV, Zhou FQ, Zhang J. AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons. Nature Chemical Biology. PMID 28192412 DOI: 10.1038/Nchembio.2298 |
0.309 |
|
2016 |
Ross B, Mehta S, Zhang J. Molecular tools for acute spatiotemporal manipulation of signal transduction. Current Opinion in Chemical Biology. 34: 135-142. PMID 27639090 DOI: 10.1016/J.Cbpa.2016.08.012 |
0.439 |
|
2016 |
Tenner B, Mehta S, Zhang J. Optical sensors to gain mechanistic insights into signaling assemblies. Current Opinion in Structural Biology. 41: 203-210. PMID 27611602 DOI: 10.1016/J.Sbi.2016.07.021 |
0.426 |
|
2015 |
Depry C, Mehta S, Li R, Zhang J. Visualization of Compartmentalized Kinase Activity Dynamics Using Adaptable BimKARs. Chemistry & Biology. PMID 26548610 DOI: 10.1016/J.Chembiol.2015.10.004 |
0.388 |
|
2015 |
Mehta S, Zhang J. Dynamic visualization of calcium-dependent signaling in cellular microdomains. Cell Calcium. PMID 25703691 DOI: 10.1016/J.Ceca.2015.01.009 |
0.451 |
|
2015 |
Clister T, Mehta S, Zhang J. Single-cell analysis of G-protein signal transduction. The Journal of Biological Chemistry. 290: 6681-8. PMID 25605723 DOI: 10.1074/Jbc.R114.616391 |
0.457 |
|
2014 |
Mehta S, Aye-Han NN, Ganesan A, Oldach L, Gorshkov K, Zhang J. Calmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin. Elife. 3: e03765. PMID 25056880 DOI: 10.7554/Elife.03765 |
0.434 |
|
2014 |
Sample V, Mehta S, Zhang J. Genetically encoded molecular probes to visualize and perturb signaling dynamics in living biological systems. Journal of Cell Science. 127: 1151-60. PMID 24634506 DOI: 10.1242/Jcs.099994 |
0.451 |
|
2014 |
Mehta S, Zhang J. Using a genetically encoded FRET-based reporter to visualize calcineurin phosphatase activity in living cells. Methods in Molecular Biology (Clifton, N.J.). 1071: 139-49. PMID 24052386 DOI: 10.1007/978-1-62703-622-1_11 |
0.413 |
|
2014 |
Mehta S, Aye-Han N, Ganesan A, Oldach L, Gorshkov K, Zhang J. Author response: Calmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin Elife. DOI: 10.7554/Elife.03765.018 |
0.336 |
|
2013 |
Mehta S, Zhang J. Using a kinase-inducible bimolecular switch to control enzyme activity in living cells. Current Protocols in Chemical Biology. 5: 227-37. PMID 24391085 DOI: 10.1002/9780470559277.Ch130090 |
0.394 |
|
2013 |
Depry C, Mehta S, Zhang J. Multiplexed visualization of dynamic signaling networks using genetically encoded fluorescent protein-based biosensors Pflugers Archiv European Journal of Physiology. 465: 373-381. PMID 23138230 DOI: 10.1007/S00424-012-1175-Y |
0.478 |
|
2013 |
Sample V, Ni Q, Mehta S, Inoue T, Zhang J. Controlling enzymatic action in living cells with a kinase-inducible bimolecular switch Acs Chemical Biology. 8: 116-121. PMID 23072367 DOI: 10.1021/Cb300393W |
0.434 |
|
2011 |
Mehta S, Zhang J. Reporting from the field: Genetically encoded fluorescent reporters uncover signaling dynamics in living biological systems Annual Review of Biochemistry. 80: 375-401. PMID 21495849 DOI: 10.1146/Annurev-Biochem-060409-093259 |
0.436 |
|
2009 |
Mehta S, Li H, Hogan PG, Cunningham KW. Domain architecture of the regulators of calcineurin (RCANs) and identification of a divergent RCAN in yeast. Molecular and Cellular Biology. 29: 2777-93. PMID 19273587 DOI: 10.1128/Mcb.01197-08 |
0.545 |
|
Show low-probability matches. |