Year |
Citation |
Score |
2024 |
Lin W, Phatarphekar A, Zhong Y, Liu L, Kwon HB, Gerwick WH, Wang Y, Mehta S, Zhang J. Light-gated integrator for highlighting kinase activity in living cells. Nature Communications. 15: 7804. PMID 39242543 DOI: 10.1038/s41467-024-51270-4 |
0.322 |
|
2024 |
Lin W, Phatarphekar A, Zhong Y, Liu L, Kwon HB, Gerwick WH, Wang Y, Mehta S, Zhang J. Light-gated Integrator for Highlighting Kinase Activity in Living Cells. Biorxiv : the Preprint Server For Biology. PMID 38562887 DOI: 10.1101/2024.03.18.585554 |
0.321 |
|
2022 |
Seong J, Wang Y. Editorial: Visualization of molecular dynamics in live cells by fluorescent protein-based biosensors. Frontiers in Cell and Developmental Biology. 10: 1054774. PMID 36313544 DOI: 10.3389/fcell.2022.1054774 |
0.66 |
|
2022 |
Lee HN, Hyeon SJ, Kim H, Sim KM, Kim Y, Ju J, Lee J, Wang Y, Ryu H, Seong J. Decreased FAK activity and focal adhesion dynamics impair proper neurite formation of medium spiny neurons in Huntington's disease. Acta Neuropathologica. PMID 35857122 DOI: 10.1007/s00401-022-02462-z |
0.661 |
|
2022 |
Pan Y, Shi LZ, Yoon CW, Preece D, Gomez-Godinez V, Lu S, Carmona C, Woo SH, Chien S, Berns MW, Liu L, Wang Y. Mechanosensor Piezo1 mediates bimodal patterns of intracellular calcium and FAK signaling. The Embo Journal. e111799. PMID 35844093 DOI: 10.15252/embj.2022111799 |
0.324 |
|
2022 |
Kim HS, Suh JS, Jang YK, Ahn SH, Choi GH, Yang JY, Lim GH, Jung Y, Jiang J, Sun J, Suk M, Wang Y, Kim TJ. Förster Resonance Energy Transfer-Based Single-Cell Imaging Reveals Piezo1-Induced Ca Flux Mediates Membrane Ruffling and Cell Survival. Frontiers in Cell and Developmental Biology. 10: 865056. PMID 35646889 DOI: 10.3389/fcell.2022.865056 |
0.325 |
|
2020 |
Yoon S, Pan Y, Shung K, Wang Y. FRET-Based Ca Biosensor Single Cell Imaging Interrogated by High-Frequency Ultrasound. Sensors (Basel, Switzerland). 20. PMID 32899249 DOI: 10.3390/S20174998 |
0.426 |
|
2020 |
Zhuang F, Bao H, Shi Q, Li J, Jiang ZL, Wang Y, Qi YX. Endothelial microparticles induced by cyclic stretch activate Src and modulate cell apoptosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32856783 DOI: 10.1096/Fj.202000581R |
0.376 |
|
2020 |
Liu L, Yu H, Zhao H, Wu Z, Long Y, Zhang J, Yan X, You Z, Zhou L, Xia T, Shi Y, Xiao B, Wang Y, Huang C, Du Y. Matrix-transmitted paratensile signaling enables myofibroblast-fibroblast cross talk in fibrosis expansion. Proceedings of the National Academy of Sciences of the United States of America. PMID 32358190 DOI: 10.1073/Pnas.1910650117 |
0.385 |
|
2020 |
Huang Z, Ouyang M, Lu S, Wang Y, Peng Q. Optogenetic Control for Investigating Subcellular Localization of Fyn Kinase Activity in Single Live Cells. Journal of Molecular Biology. PMID 32198118 DOI: 10.1016/J.Jmb.2020.03.015 |
0.364 |
|
2020 |
Huang Z, Wu Y, Allen ME, Pan Y, Kyriakakis P, Lu S, Chang YJ, Wang X, Chien S, Wang Y. Engineering light-controllable CAR T cells for cancer immunotherapy. Science Advances. 6: eaay9209. PMID 32128416 DOI: 10.1126/Sciadv.Aay9209 |
0.325 |
|
2020 |
Dutta P, Zhang L, Zhang H, Peng Q, Montgrain PR, Wang Y, Song Y, Li J, Li WX. Unphosphorylated STAT3 in heterochromatin formation and tumor suppression in lung cancer. Bmc Cancer. 20: 145. PMID 32087696 DOI: 10.1186/S12885-020-6649-2 |
0.311 |
|
2020 |
서정수, 이찬빈, 판이자, 왕잉샤이오, 정영미, 김태진, Suh J, Lee C, Pan Y, Wang Y, Jung Y, Kim T. A Study on Single Cell Polarized Signals Using Polydimethylsiloxane-based Micropatterned Channel System Korean Journal of Chemical Engineering. 58: 122-126. DOI: 10.9713/Kcer.2020.58.1.122 |
0.334 |
|
2019 |
Qin Q, Laub S, Shi Y, Ouyang M, Peng Q, Zhang J, Wang Y, Lu S. for Ratiometric and High-Throughput Live-Cell Image Visualization and Quantitation. Frontiers in Physics. 7. PMID 33163483 DOI: 10.3389/Fphy.2019.00154 |
0.422 |
|
2019 |
Allen ME, Zhou W, Thangaraj J, Kyriakakis P, Wu Y, Huang Z, Ho P, Pan Y, Limsakul P, Xu X, Wang Y. An AND-Gated Drug and Photoactivatable Cre- System for Spatiotemporal Control in Cell-Based Therapeutics. Acs Synthetic Biology. PMID 31592660 DOI: 10.1021/Acssynbio.9B00175 |
0.361 |
|
2019 |
Wan R, Wu J, Ouyang M, Lei L, Wei J, Peng Q, Harrison R, Wu Y, Cheng B, Li K, Zhu C, Tang L, Wang Y, Lu S. Biophysical basis underlying dynamic Lck activation visualized by ZapLck FRET biosensor. Science Advances. 5: eaau2001. PMID 31223643 DOI: 10.1126/Sciadv.Aau2001 |
0.409 |
|
2019 |
Kim TJ, Lei L, Seong J, Suh JS, Jang YK, Jung SH, Sun J, Kim DH, Wang Y. Matrix Rigidity-Dependent Regulation of Ca at Plasma Membrane Microdomains by FAK Visualized by Fluorescence Resonance Energy Transfer. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 6: 1801290. PMID 30828523 DOI: 10.1002/Advs.201801290 |
0.722 |
|
2019 |
Pan Y, Lu S, Lei L, Lamberto I, Wang Y, Pasquale EB, Wang Y. A genetically encoded FRET biosensor for visualizing EphA4 activity in different compartments of the plasma membrane. Acs Sensors. PMID 30608127 DOI: 10.1021/Acssensors.8B00465 |
0.448 |
|
2018 |
Wang P, Liang J, Shi LZ, Wang Y, Zhang P, Ouyang M, Preece D, Peng Q, Shao L, Fan J, Sun J, Li SS, Berns MW, Zhao H, Wang Y. Visualizing Spatiotemporal Dynamics of Intercellular Mechanotransmission upon Wounding. Acs Photonics. 5: 3565-3574. PMID 31069245 DOI: 10.1021/Acsphotonics.8B00383 |
0.455 |
|
2018 |
Ouyang M, Wan R, Qin Q, Peng Q, Wang P, Wu J, Allen M, Shi Y, Laub S, Deng L, Lu S, Wang Y. A sensitive FRET biosensor reveals Fyn kinase regulation by sub-membrane localization. Acs Sensors. PMID 30588803 DOI: 10.1021/Acssensors.8B00896 |
0.477 |
|
2018 |
Peng Q, Lu S, Shi Y, Pan Y, Limsakul P, Chernov AV, Qiu J, Chai X, Shi Y, Wang P, Ji Y, Li YJ, Strongin AY, Verkhusha VV, Izpisua Belmonte JC, ... ... Wang Y, ... ... Wang Y, et al. Coordinated histone modifications and chromatin reorganization in a single cell revealed by FRET biosensors. Proceedings of the National Academy of Sciences of the United States of America. PMID 30478057 DOI: 10.1073/Pnas.1811818115 |
0.324 |
|
2018 |
Tang X, Liu Y, Xiao Q, Yao Q, Allen M, Wang Y, Gao L, Qi Y, Zhang P. Pathological cyclic strain promotes proliferation of vascular smooth muscle cells via the ACTH/ERK/STAT3 pathway. Journal of Cellular Biochemistry. PMID 29943847 DOI: 10.1002/Jcb.26839 |
0.398 |
|
2018 |
Conway JRW, Warren SC, Herrmann D, Murphy KJ, Cazet AS, Vennin C, Shearer RF, Killen MJ, Magenau A, Mélénec P, Pinese M, Nobis M, Zaratzian A, Boulghourjian A, Da Silva AM, ... ... Wang Y, et al. Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer. Cell Reports. 23: 3312-3326. PMID 29898401 DOI: 10.1016/J.Celrep.2018.05.038 |
0.301 |
|
2018 |
Limsakul P, Peng Q, Wu Y, Allen ME, Liang J, Remacle AG, Lopez T, Ge X, Kay BK, Zhao H, Strongin AY, Yang XL, Lu S, Wang Y. Directed Evolution to Engineer Monobody for FRET Biosensor Assembly and Imaging at Live-Cell Surface. Cell Chemical Biology. PMID 29396288 DOI: 10.1016/J.Chembiol.2018.01.002 |
0.424 |
|
2018 |
Pan Y, Yoon S, Sun J, Huang Z, Lee C, Allen M, Wu Y, Chang YJ, Sadelain M, Shung KK, Chien S, Wang Y. Mechanogenetics for the remote and noninvasive control of cancer immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 29343642 DOI: 10.1073/Pnas.1714900115 |
0.402 |
|
2017 |
Sun J, Lei L, Tsai CM, Wang Y, Shi Y, Ouyang M, Lu S, Seong J, Kim TJ, Wang P, Huang M, Xu X, Nizet V, Chien S, Wang Y. Engineered proteins with sensing and activating modules for automated reprogramming of cellular functions. Nature Communications. 8: 477. PMID 28883531 DOI: 10.1038/S41467-017-00569-6 |
0.696 |
|
2017 |
Wan Q, TruongVo T, Steele HE, Ozcelikkale A, Han B, Wang Y, Oh J, Yokota H, Na S. Subcellular domain-dependent molecular hierarchy of SFK and FAK in mechanotransduction and cytokine signaling. Scientific Reports. 7: 9033. PMID 28831165 DOI: 10.1038/S41598-017-09495-5 |
0.43 |
|
2017 |
Yoon S, Wang P, Peng Q, Wang Y, Shung KK. Acoustic-transfection for genomic manipulation of single-cells using high frequency ultrasound. Scientific Reports. 7: 5275. PMID 28706248 DOI: 10.1038/S41598-017-05722-1 |
0.341 |
|
2017 |
Seong J, Huang M, Sim KM, Kim H, Wang Y. FRET-based Visualization of PDGF Receptor Activation at Membrane Microdomains. Scientific Reports. 7: 1593. PMID 28487538 DOI: 10.1038/S41598-017-01789-Y |
0.727 |
|
2017 |
Mao M, Wang L, Chang CC, Rothenberg KE, Huang J, Wang Y, Hoffman BD, Liton PB, Yuan F. Involvement of a Rac1-Dependent Macropinocytosis Pathway in Plasmid DNA Delivery by Electrotransfection. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28129959 DOI: 10.1016/J.Ymthe.2016.12.009 |
0.417 |
|
2016 |
Li K, Xiang X, Sun J, He HT, Wu J, Wang Y, Zhu C. Imaging Spatiotemporal Activities of ZAP-70 in Live T Cells Using a FRET-Based Biosensor. Annals of Biomedical Engineering. PMID 27384937 DOI: 10.1007/S10439-016-1683-6 |
0.468 |
|
2016 |
Wu Y, Zhang K, Seong J, Fan J, Chien S, Wang Y, Lu S. In-situ coupling between kinase activities and protein dynamics within single focal adhesions. Scientific Reports. 6: 29377. PMID 27383747 DOI: 10.1038/Srep29377 |
0.716 |
|
2016 |
Qi YX, Yao QP, Huang K, Shi Q, Zhang P, Wang GL, Han Y, Bao H, Wang L, Li HP, Shen BR, Wang Y, Chien S, Jiang ZL. Nuclear envelope proteins modulate proliferation of vascular smooth muscle cells during cyclic stretch application. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114541 DOI: 10.1073/Pnas.1604569113 |
0.319 |
|
2016 |
Wang Y. New technologies of molecular engineering and screening for cell signaling studies. Molecular Biology of the Cell. 27: 875-6. PMID 26976929 DOI: 10.1091/Mbc.E15-11-0762 |
0.423 |
|
2016 |
Yoon S, Kim MG, Chiu CT, Hwang JY, Kim HH, Wang Y, Shung KK. Direct and sustained intracellular delivery of exogenous molecules using acoustic-transfection with high frequency ultrasound. Scientific Reports. 6: 20477. PMID 26843283 DOI: 10.1038/Srep20477 |
0.422 |
|
2016 |
Le Borgne M, Raju S, Zinselmeyer BH, Le VT, Li J, Wang Y, Miller MJ, Shaw AS. Real-Time Analysis of Calcium Signals during the Early Phase of T Cell Activation Using a Genetically Encoded Calcium Biosensor. Journal of Immunology (Baltimore, Md. : 1950). PMID 26746192 DOI: 10.4049/Jimmunol.1502414 |
0.404 |
|
2016 |
Jin Z, Liu H, Allen M, Li X, Xiang R, Li D, Wang Y, Li J, Hu J. Polarizing CD8+ Central Memory T Cells and Th1 Cells By Lenalidomide Contributes to the Antitumor Function of CD19 CAR-T Cells in Killing Diffused Large B Cell Lymphoma in Vitro Blood. 128: 4190-4190. DOI: 10.1182/Blood.V128.22.4190.4190 |
0.301 |
|
2016 |
Yoon S, Wang Y, Shung KK. Optimization of input parameters of acoustic-transfection for the intracellular delivery of macromolecules using FRET-based biosensors Proceedings of Spie. 9723: 6. DOI: 10.1117/12.2212691 |
0.354 |
|
2015 |
Wang X, Sun J, Xu Q, Chowdhury F, Roein-Peikar M, Wang Y, Ha T. Integrin Molecular Tension within Motile Focal Adhesions. Biophysical Journal. 109: 2259-2267. PMID 26636937 DOI: 10.1016/J.Bpj.2015.10.029 |
0.4 |
|
2015 |
Nishitani WS, Alencar AM, Wang Y. Correction: Rapid and Localized Mechanical Stimulation and Adhesion Assay: TRPM7 Involvement in Calcium Signaling and Cell Adhesion. Plos One. 10: e0138281. PMID 26366996 DOI: 10.1371/journal.pone.0138281 |
0.786 |
|
2015 |
Zhuo Y, Qian T, Wu Y, Seong J, Gong Y, Ma H, Wang Y, Lu S. Subcellular and Dynamic Coordination between Src Activity and Cell Protrusion in Microenvironment. Scientific Reports. 5: 12963. PMID 26261043 DOI: 10.1038/Srep12963 |
0.739 |
|
2015 |
Chung EY, Ochs CJ, Wang Y, Lei L, Qin Q, Smith AM, Strongin AY, Kamm R, Qi YX, Lu S, Wang Y. Activatable and Cell-Penetrable Multiplex FRET Nanosensor for Profiling MT1-MMP Activity in Single Cancer Cells. Nano Letters. 15: 5025-32. PMID 26203778 DOI: 10.1021/Acs.Nanolett.5B01047 |
0.42 |
|
2015 |
Lee KL, Guevarra MD, Nguyen AM, Chua MC, Wang Y, Jacobs CR. The primary cilium functions as a mechanical and calcium signaling nexus. Cilia. 4: 7. PMID 26029358 DOI: 10.1186/S13630-015-0016-Y |
0.315 |
|
2015 |
Nishitani WS, Alencar AM, Wang Y. Rapid and Localized Mechanical Stimulation and Adhesion Assay: TRPM7 Involvement in Calcium Signaling and Cell Adhesion. Plos One. 10: e0126440. PMID 25946314 DOI: 10.1371/Journal.Pone.0126440 |
0.789 |
|
2015 |
Han Y, Wang L, Yao QP, Zhang P, Liu B, Wang GL, Shen BR, Cheng B, Wang Y, Jiang ZL, Qi YX. Nuclear envelope proteins Nesprin2 and LaminA regulate proliferation and apoptosis of vascular endothelial cells in response to shear stress. Biochimica Et Biophysica Acta. 1853: 1165-73. PMID 25721888 DOI: 10.1016/J.Bbamcr.2015.02.013 |
0.344 |
|
2015 |
Kim TJ, Joo C, Seong J, Vafabakhsh R, Botvinick EL, Berns MW, Palmer AE, Wang N, Ha T, Jakobsson E, Sun J, Wang Y. Distinct mechanisms regulating mechanical force-induced Ca²⁺ signals at the plasma membrane and the ER in human MSCs. Elife. 4: e04876. PMID 25667984 DOI: 10.7554/Elife.04876 |
0.677 |
|
2015 |
Gomez-Godinez V, Preece D, Shi L, Khatibzadeh N, Rosales D, Pan Y, Lei L, Wang Y, Berns MW. Laser-induced shockwave paired with FRET: a method to study cell signaling. Microscopy Research and Technique. 78: 195-9. PMID 25639252 DOI: 10.1002/Jemt.22463 |
0.334 |
|
2015 |
Sun J, Jakobsson E, Wang Y, Brinker CJ. Nanoporous silica-based protocells at multiple scales for designs of life and nanomedicine. Life (Basel, Switzerland). 5: 214-29. PMID 25607812 DOI: 10.3390/Life5010214 |
0.305 |
|
2015 |
Kim TJ, Zheng S, Sun J, Muhamed I, Wu J, Lei L, Kong X, Leckband DE, Wang Y. Dynamic visualization of α-catenin reveals rapid, reversible conformation switching between tension states. Current Biology : Cb. 25: 218-24. PMID 25544608 DOI: 10.1016/J.Cub.2014.11.017 |
0.345 |
|
2014 |
Aung A, Seo YN, Lu S, Wang Y, Jamora C, del Álamo JC, Varghese S. 3D traction stresses activate protease-dependent invasion of cancer cells. Biophysical Journal. 107: 2528-37. PMID 25468332 DOI: 10.1016/J.Bpj.2014.07.078 |
0.388 |
|
2014 |
Liu B, Lu S, Hu YL, Liao X, Ouyang M, Wang Y. RhoA and membrane fluidity mediates the spatially polarized Src/FAK activation in response to shear stress. Scientific Reports. 4: 7008. PMID 25387906 DOI: 10.1038/Srep07008 |
0.422 |
|
2014 |
Kim TJ, Sun J, Lu S, Qi YX, Wang Y. Prolonged mechanical stretch initiates intracellular calcium oscillations in human mesenchymal stem cells. Plos One. 9: e109378. PMID 25329052 DOI: 10.1371/Journal.Pone.0109378 |
0.411 |
|
2014 |
Hwang K, Wu P, Kim T, Lei L, Tian S, Wang Y, Lu Y. Photocaged DNAzymes as a general method for sensing metal ions in living cells. Angewandte Chemie (International Ed. in English). 53: 13798-802. PMID 25314680 DOI: 10.1002/Anie.201408333 |
0.32 |
|
2014 |
Sun C, Ouyang M, Cao Z, Ma S, Alqublan H, Sriranganathan N, Wang Y, Lu C. Electroporation-delivered fluorescent protein biosensors for probing molecular activities in cells without genetic encoding. Chemical Communications (Cambridge, England). 50: 11536-9. PMID 25133322 DOI: 10.1039/C4Cc04730C |
0.395 |
|
2014 |
Hu YL, Lu S, Szeto KW, Sun J, Wang Y, Lasheras JC, Chien S. FAK and paxillin dynamics at focal adhesions in the protrusions of migrating cells. Scientific Reports. 4: 6024. PMID 25113375 DOI: 10.1038/Srep06024 |
0.471 |
|
2014 |
Tan Y, Tajik A, Chen J, Jia Q, Chowdhury F, Wang L, Chen J, Zhang S, Hong Y, Yi H, Wu DC, Zhang Y, Wei F, Poh YC, Seong J, ... ... Wang Y, et al. Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression. Nature Communications. 5: 4619. PMID 25099074 DOI: 10.1038/Ncomms5619 |
0.676 |
|
2014 |
Lu S, Wang Y. Single-cell imaging of mechanotransduction in endothelial cells. Progress in Molecular Biology and Translational Science. 126: 25-51. PMID 25081613 DOI: 10.1016/B978-0-12-394624-9.00002-6 |
0.466 |
|
2014 |
Lu S, Seong J, Wang Y, Chang SC, Eichorst JP, Ouyang M, Li JY, Chien S, Wang Y. Decipher the dynamic coordination between enzymatic activity and structural modulation at focal adhesions in living cells. Scientific Reports. 4: 5756. PMID 25056908 DOI: 10.1038/Srep05756 |
0.802 |
|
2014 |
Kim TJ, Sun J, Lu S, Zhang J, Wang Y. The regulation of β-adrenergic receptor-mediated PKA activation by substrate stiffness via microtubule dynamics in human MSCs. Biomaterials. 35: 8348-56. PMID 24973298 DOI: 10.1016/J.Biomaterials.2014.06.018 |
0.417 |
|
2014 |
Hum JM, Day RN, Bidwell JP, Wang Y, Pavalko FM. Mechanical loading in osteocytes induces formation of a Src/Pyk2/MBD2 complex that suppresses anabolic gene expression. Plos One. 9: e97942. PMID 24841674 DOI: 10.1371/Journal.Pone.0097942 |
0.342 |
|
2014 |
Lei L, Lu S, Wang Y, Kim T, Mehta D, Wang Y. The role of mechanical tension on lipid raft dependent PDGF-induced TRPC6 activation. Biomaterials. 35: 2868-77. PMID 24397990 DOI: 10.1016/J.Biomaterials.2013.12.030 |
0.451 |
|
2014 |
Ouyang M, Lu S, Wang Y. Genetically encoded fluorescent biosensors for live-cell imaging of MT1-MMP protease activity. Methods in Molecular Biology (Clifton, N.J.). 1071: 163-74. PMID 24052388 DOI: 10.1007/978-1-62703-622-1_13 |
0.406 |
|
2014 |
Kim T, Joo C, Seong J, Vafabakhsh R, Botvinick EL, Berns MW, Palmer AE, Wang N, Ha T, Jakobsson E, Sun J, Wang Y. Author response: Distinct mechanisms regulating mechanical force-induced Ca2+ signals at the plasma membrane and the ER in human MSCs Elife. DOI: 10.7554/Elife.04876.015 |
0.677 |
|
2013 |
Seong J, Tajik A, Sun J, Guan JL, Humphries MJ, Craig SE, Shekaran A, GarcÃa AJ, Lu S, Lin MZ, Wang N, Wang Y. Distinct biophysical mechanisms of focal adhesion kinase mechanoactivation by different extracellular matrix proteins. Proceedings of the National Academy of Sciences of the United States of America. 110: 19372-7. PMID 24222685 DOI: 10.1073/Pnas.1307405110 |
0.776 |
|
2013 |
Ntziachristos V, Achilefu S, Wang YP, Lin M. Special section on fluorescence molecular imaging honoring Prof. Roger Tsien, a pioneer in biomedical optics. Journal of Biomedical Optics. 18: 101301. PMID 24169645 DOI: 10.1117/1.Jbo.18.10.101301 |
0.539 |
|
2013 |
Liao X, Lu S, Wu Y, Xu W, Zhuo Y, Peng Q, Li B, Zhang L, Wang Y. The effect of differentiation induction on FAK and Src activity in live HMSCs visualized by FRET. Plos One. 8: e72233. PMID 24015220 DOI: 10.1371/Journal.Pone.0072233 |
0.448 |
|
2013 |
Nobis M, McGhee EJ, Morton JP, Schwarz JP, Karim SA, Quinn J, Edward M, Campbell AD, McGarry LC, Evans TR, Brunton VG, Frame MC, Carragher NO, Wang Y, Sansom OJ, et al. Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of src in pancreatic cancer. Cancer Research. 73: 4674-86. PMID 23749641 DOI: 10.1158/0008-5472.Can-12-4545 |
0.374 |
|
2013 |
Seong J, Wang N, Wang Y. Mechanotransduction at focal adhesions: from physiology to cancer development. Journal of Cellular and Molecular Medicine. 17: 597-604. PMID 23601032 DOI: 10.1111/Jcmm.12045 |
0.712 |
|
2013 |
Lu S, Wang Y, Huang H, Pan Y, Chaney EJ, Boppart SA, Ozer H, Strongin AY, Wang Y. Quantitative FRET imaging to visualize the invasiveness of live breast cancer cells. Plos One. 8: e58569. PMID 23516511 DOI: 10.1371/Journal.Pone.0058569 |
0.389 |
|
2013 |
Ouyang M, Lu S, Kim T, Chen CE, Seong J, Leckband DE, Wang F, Reynolds AB, Schwartz MA, Wang Y. N-cadherin regulates spatially polarized signals through distinct p120ctn and β-catenin-dependent signalling pathways. Nature Communications. 4: 1589. PMID 23481397 DOI: 10.1038/Ncomms2560 |
0.701 |
|
2013 |
Lin LJ, Grimme JM, Sun J, Lu S, Gai L, Cropek DM, Wang Y. The antagonistic roles of PDGF and integrin αvβ3 in regulating ROS production at focal adhesions. Biomaterials. 34: 3807-15. PMID 23465490 DOI: 10.1016/J.Biomaterials.2013.01.092 |
0.398 |
|
2013 |
Qian T, Lu S, Ma H, Fang J, Zhong W, Wang Y. FRET imaging of calcium signaling in live cells in the microenvironment. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 431-8. PMID 23250282 DOI: 10.1039/C2Ib20264F |
0.422 |
|
2013 |
Lu S, Wang Y, Huang H, Pan Y, Chaney EJ, Boppart SA, Ozer H, Strongin AY, Wang Y. Profile the invasive MT1-MMP activity in breast cancer cell lines utilizing GM6001 washout assay. Plos One. DOI: 10.1371/Journal.Pone.0058569.G004 |
0.317 |
|
2012 |
Wang R, Lei L, Wang Y, Levine AJ, Popescu G. Dispersion-relation fluorescence spectroscopy. Physical Review Letters. 109: 188104. PMID 23215337 DOI: 10.1103/Physrevlett.109.188104 |
0.305 |
|
2012 |
Eichorst JP, Clegg RM, Wang Y. Red-shifted fluorescent proteins monitor enzymatic activity in live HT-1080 cells with fluorescence lifetime imaging microscopy (FLIM). Journal of Microscopy. 248: 77-89. PMID 22971220 DOI: 10.1111/J.1365-2818.2012.03652.X |
0.77 |
|
2012 |
Liao X, Lu S, Zhuo Y, Winter C, Xu W, Wang Y. Visualization of Src and FAK activity during the differentiation process from HMSCs to osteoblasts. Plos One. 7: e42709. PMID 22900044 DOI: 10.1371/Journal.Pone.0042709 |
0.419 |
|
2012 |
Birukova AA, Tian Y, Dubrovskyi O, Zebda N, Sarich N, Tian X, Wang Y, Birukov KG. VE-cadherin trans-interactions modulate Rac activation and enhancement of lung endothelial barrier by iloprost. Journal of Cellular Physiology. 227: 3405-16. PMID 22213015 DOI: 10.1002/Jcp.24041 |
0.44 |
|
2011 |
Xiang X, Sun J, Wu J, He HT, Wang Y, Zhu C. A FRET-Based Biosensor for Imaging SYK Activities in Living Cells. Cellular and Molecular Bioengineering. 4: 670-677. PMID 25541586 DOI: 10.1007/S12195-011-0211-X |
0.454 |
|
2011 |
Nishitani WS, Saif TA, Wang Y. Calcium signaling in live cells on elastic gels under mechanical vibration at subcellular levels. Plos One. 6: e26181. PMID 22053183 DOI: 10.1371/Journal.Pone.0026181 |
0.772 |
|
2011 |
Seong J, Lu S, Wang Y. Live Cell Imaging of Src/FAK Signaling by FRET. Cellular and Molecular Bioengineering. 2: 138-147. PMID 21857884 DOI: 10.1007/S12195-011-0161-3 |
0.741 |
|
2011 |
Seong J, Ouyang M, Kim T, Sun J, Wen PC, Lu S, Zhuo Y, Llewellyn NM, Schlaepfer DD, Guan JL, Chien S, Wang Y. Detection of focal adhesion kinase activation at membrane microdomains by fluorescence resonance energy transfer. Nature Communications. 2: 406. PMID 21792185 DOI: 10.1038/Ncomms1414 |
0.74 |
|
2011 |
Lu S, Kim TJ, Chen CE, Ouyang M, Seong J, Liao X, Wang Y. Computational analysis of the spatiotemporal coordination of polarized PI3K and Rac1 activities in micro-patterned live cells. Plos One. 6: e21293. PMID 21738630 DOI: 10.1371/Journal.Pone.0021293 |
0.739 |
|
2011 |
Eichorst JP, Huang H, Clegg RM, Wang Y. Phase differential enhancement of FLIM to distinguish FRET components of a biosensor for monitoring molecular activity of Membrane Type 1 Matrix Metalloproteinase in live cells. Journal of Fluorescence. 21: 1763-77. PMID 21519891 DOI: 10.1007/S10895-011-0871-X |
0.775 |
|
2011 |
Liu B, Lu S, Zheng S, Jiang Z, Wang Y. Two distinct phases of calcium signalling under flow. Cardiovascular Research. 91: 124-33. PMID 21285296 DOI: 10.1093/Cvr/Cvr033 |
0.368 |
|
2010 |
Gawlik K, Remacle AG, Shiryaev SA, Golubkov VS, Ouyang M, Wang Y, Strongin AY. A femtomol range FRET biosensor reports exceedingly low levels of cell surface furin: implications for the processing of anthrax protective antigen. Plos One. 5: e11305. PMID 20585585 DOI: 10.1371/Journal.Pone.0011305 |
0.424 |
|
2010 |
Qian T, Wang Y. Micro/nano-fabrication technologies for cell biology. Medical & Biological Engineering & Computing. 48: 1023-32. PMID 20490938 DOI: 10.1007/S11517-010-0632-Z |
0.347 |
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2010 |
Liu B, Kim TJ, Wang Y. Live cell imaging of mechanotransduction. Journal of the Royal Society, Interface / the Royal Society. 7: S365-75. PMID 20356874 DOI: 10.1098/Rsif.2010.0042.Focus |
0.433 |
|
2010 |
Ouyang M, Huang H, Shaner NC, Remacle AG, Shiryaev SA, Strongin AY, Tsien RY, Wang Y. Simultaneous visualization of protumorigenic Src and MT1-MMP activities with fluorescence resonance energy transfer. Cancer Research. 70: 2204-12. PMID 20197470 DOI: 10.1158/0008-5472.Can-09-3698 |
0.421 |
|
2009 |
Wang Y, Wang N. FRET and mechanobiology. Integrative Biology : Quantitative Biosciences From Nano to Macro. 1: 565-73. PMID 20016756 DOI: 10.1039/B913093B |
0.425 |
|
2009 |
Wang Y, Flores L, Lu S, Miao H, Li YS, Chien S. Shear Stress Regulates the Flk-1/Cbl/PI3K/NF-κB Pathway Via Actin and Tyrosine Kinases. Cellular and Molecular Bioengineering. 2: 341-350. PMID 20011623 DOI: 10.1007/S12195-009-0069-3 |
0.337 |
|
2009 |
Poh YC, Na S, Chowdhury F, Ouyang M, Wang Y, Wang N. Rapid activation of Rac GTPase in living cells by force is independent of Src. Plos One. 4: e7886. PMID 19924282 DOI: 10.1371/Journal.Pone.0007886 |
0.451 |
|
2009 |
Kim TJ, Xu J, Dong R, Lu S, Nuzzo R, Wang Y. Visualizing the effect of microenvironment on the spatiotemporal RhoA and Src activities in living cells by FRET. Small (Weinheim An Der Bergstrasse, Germany). 5: 1453-9. PMID 19334011 DOI: 10.1002/Smll.200801846 |
0.517 |
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2009 |
Na S, Chowdhury F, Tay B, Ouyang M, Gregor M, Wang Y, Wiche G, Wang N. Plectin contributes to mechanical properties of living cells. American Journal of Physiology. Cell Physiology. 296: C868-77. PMID 19244477 DOI: 10.1152/Ajpcell.00604.2008 |
0.365 |
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2009 |
Seong J, Lu S, Ouyang M, Huang H, Zhang J, Frame MC, Wang Y. Visualization of Src activity at different compartments of the plasma membrane by FRET imaging. Chemistry & Biology. 16: 48-57. PMID 19171305 DOI: 10.1016/J.Chembiol.2008.11.007 |
0.707 |
|
2009 |
Kim TJ, Seong J, Ouyang M, Sun J, Lu S, Hong JP, Wang N, Wang Y. Substrate rigidity regulates Ca2+ oscillation via RhoA pathway in stem cells. Journal of Cellular Physiology. 218: 285-93. PMID 18844232 DOI: 10.1002/Jcp.21598 |
0.71 |
|
2009 |
Hsieh AL, Wang Y, Ross RS, Berns MW, McCulloch AD. Mechanotransduction in Single Cardiac Myocyte Studied Using Laser Tweezers and FRET Biophysical Journal. 96: 316a. DOI: 10.1016/J.Bpj.2008.12.1582 |
0.386 |
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2008 |
Eichorst JP, Lu S, Xu J, Wang Y. Differential RhoA dynamics in migratory and stationary cells measured by FRET and automated image analysis. Plos One. 3: e4082. PMID 19114999 DOI: 10.1371/Journal.Pone.0004082 |
0.793 |
|
2008 |
Ouyang M, Sun J, Chien S, Wang Y. Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors. Proceedings of the National Academy of Sciences of the United States of America. 105: 14353-8. PMID 18799748 DOI: 10.1073/Pnas.0807537105 |
0.505 |
|
2008 |
Lu S, Ouyang M, Seong J, Zhang J, Chien S, Wang Y. The spatiotemporal pattern of Src activation at lipid rafts revealed by diffusion-corrected FRET imaging. Plos Computational Biology. 4: e1000127. PMID 18711637 DOI: 10.1371/Journal.Pcbi.1000127 |
0.709 |
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2008 |
Wang Y, Shyy JY, Chien S. Fluorescence proteins, live-cell imaging, and mechanobiology: seeing is believing. Annual Review of Biomedical Engineering. 10: 1-38. PMID 18647110 DOI: 10.1146/Annurev.Bioeng.010308.161731 |
0.401 |
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2008 |
Na S, Collin O, Chowdhury F, Tay B, Ouyang M, Wang Y, Wang N. Rapid signal transduction in living cells is a unique feature of mechanotransduction. Proceedings of the National Academy of Sciences of the United States of America. 105: 6626-31. PMID 18456839 DOI: 10.1073/Pnas.0711704105 |
0.411 |
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2008 |
Ouyang M, Lu S, Li XY, Xu J, Seong J, Giepmans BN, Shyy JY, Weiss SJ, Wang Y. Visualization of polarized membrane type 1 matrix metalloproteinase activity in live cells by fluorescence resonance energy transfer imaging. The Journal of Biological Chemistry. 283: 17740-8. PMID 18441011 DOI: 10.1074/Jbc.M709872200 |
0.703 |
|
2008 |
Wang Y, Lu S. The application of FRET biosensors to visualize Src activation Proceedings of Spie. 6868. DOI: 10.1117/12.764713 |
0.538 |
|
2007 |
Wang Y, Chien S. Analysis of integrin signaling by fluorescence resonance energy transfer. Methods in Enzymology. 426: 177-201. PMID 17697885 DOI: 10.1016/S0076-6879(07)26009-4 |
0.423 |
|
2007 |
Botvinick EL, Wang Y. Laser tweezers in the study of mechanobiology in live cells. Methods in Cell Biology. 82: 497-523. PMID 17586270 DOI: 10.1016/S0091-679X(06)82018-2 |
0.464 |
|
2007 |
Wang Y, Chang J, Chen KD, Li S, Li JY, Wu C, Chien S. Selective adapter recruitment and differential signaling networks by VEGF vs. shear stress. Proceedings of the National Academy of Sciences of the United States of America. 104: 8875-9. PMID 17496149 DOI: 10.1073/Pnas.0703088104 |
0.341 |
|
2006 |
Hu YL, Haga JH, Miao H, Wang Y, Li YS, Chien S. Roles of microfilaments and microtubules in paxillin dynamics. Biochemical and Biophysical Research Communications. 348: 1463-71. PMID 16920067 DOI: 10.1016/J.Bbrc.2006.08.022 |
0.409 |
|
2006 |
Wang Y, Jin G, Miao H, Li JY, Usami S, Chien S. Integrins regulate VE-cadherin and catenins: dependence of this regulation on Src, but not on Ras. Proceedings of the National Academy of Sciences of the United States of America. 103: 1774-9. PMID 16446427 DOI: 10.1073/Pnas.0510774103 |
0.459 |
|
2005 |
Wang Y, Botvinick EL, Zhao Y, Berns MW, Usami S, Tsien RY, Chien S. Visualizing the mechanical activation of Src. Nature. 434: 1040-5. PMID 15846350 DOI: 10.1038/Nature03469 |
0.503 |
|
2004 |
Wang Y, Chang J, Li YC, Li YS, Shyy JY, Chien S. Shear stress and VEGF activate IKK via the Flk-1/Cbl/Akt signaling pathway. American Journal of Physiology. Heart and Circulatory Physiology. 286: H685-92. PMID 14551058 DOI: 10.1152/Ajpheart.00237.2003 |
0.363 |
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2003 |
Shiu YT, Li S, Yuan S, Wang Y, Nguyen P, Chien S. Shear stress-induced c-fos activation is mediated by Rho in a calcium-dependent manner. Biochemical and Biophysical Research Communications. 303: 548-55. PMID 12659853 DOI: 10.1016/S0006-291X(03)00388-7 |
0.378 |
|
2002 |
Wang Y, Miao H, Li S, Chen KD, Li YS, Yuan S, Shyy JY, Chien S. Interplay between integrins and FLK-1 in shear stress-induced signaling. American Journal of Physiology. Cell Physiology. 283: C1540-7. PMID 12372815 DOI: 10.1152/Ajpcell.00222.2002 |
0.377 |
|
2002 |
Miao H, Yuan S, Wang Y, Tsygankov A, Chien S. Role of Cbl in shear-activation of PI 3-kinase and JNK in endothelial cells. Biochemical and Biophysical Research Communications. 292: 892-9. PMID 11944898 DOI: 10.1006/Bbrc.2002.6750 |
0.347 |
|
2002 |
Li S, Butler P, Wang Y, Hu Y, Han DC, Usami S, Guan JL, Chien S. The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 3546-51. PMID 11891289 DOI: 10.1073/Pnas.052018099 |
0.413 |
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