Konstantin A. Tsetsarkin, Ph.D. - Publications

Affiliations: 
2009 University of Texas Medical Branch, Galveston, TX 
Area:
Virology Biology, Molecular Biology

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Oliveira G, Vogels CBF, Zolfaghari A, Saraf S, Klitting R, Weger-Lucarelli J, P Leon K, Ontiveros CO, Agarwal R, Tsetsarkin KA, Harris E, Ebel GD, Wohl S, Grubaugh ND, Andersen KG. Genomic and phenotypic analyses suggest moderate fitness differences among Zika virus lineages. Plos Neglected Tropical Diseases. 17: e0011055. PMID 36753510 DOI: 10.1371/journal.pntd.0011055  0.494
2021 Pletnev AG, Maximova OA, Liu G, Kenney H, Nagata BM, Zagorodnyaya T, Moore I, Chumakov K, Tsetsarkin KA. Epididymal epithelium propels early sexual transmission of Zika virus in the absence of interferon signaling. Nature Communications. 12: 2469. PMID 33927207 DOI: 10.1038/s41467-021-22729-5  0.389
2020 Lemos D, Stuart JB, Louie W, Singapuri A, Ramírez AL, Watanabe J, Usachenko J, Keesler RI, Martin CS, Li T, Martyn C, Oliveira G, Saraf S, Grubaugh ND, Andersen KG, ... ... Tsetsarkin KA, et al. Two sides of a coin: a Zika virus mutation selected in pregnant rhesus macaques promotes fetal infection in mice but at a cost of reduced fitness in nonpregnant macaques and diminished transmissibility by vectors. Journal of Virology. PMID 32999034 DOI: 10.1128/JVI.01605-20  0.485
2020 Tsetsarkin KA, Acklin JA, Liu G, Kenney H, Teterina NL, Pletnev AG, Lim JK. Zika virus tropism during early infection of the testicular interstitium and its role in viral pathogenesis in the testes. Plos Pathogens. 16: e1008601. PMID 32614902 DOI: 10.1371/Journal.Ppat.1008601  0.542
2020 Volkova E, Tsetsarkin KA, Sippert E, Assis F, Liu G, Rios M, Pletnev AG. Novel Approach for Insertion of Heterologous Sequences into Full-Length ZIKV Genome Results in Superior Level of Gene Expression and Insert Stability. Viruses. 12. PMID 31947825 DOI: 10.3390/V12010061  0.507
2019 Tsetsarkin KA, Maximova OA, Liu G, Kenney H, Teterina NL, Pletnev AG. Stable and Highly Immunogenic MicroRNA-Targeted Single-Dose Live Attenuated Vaccine Candidate against Tick-Borne Encephalitis Constructed Using Genetic Backbone of Langat Virus. Mbio. 10. PMID 31015334 DOI: 10.1128/Mbio.02904-18  0.57
2019 Li G, Bos S, Tsetsarkin KA, Pletnev AG, Desprès P, Gadea G, Zhao RY. The Roles of prM-E Proteins in Historical and Epidemic Zika Virus-mediated Infection and Neurocytotoxicity. Viruses. 11. PMID 30769824 DOI: 10.3390/V11020157  0.59
2018 Tsetsarkin KA, Maximova OA, Liu G, Kenney H, Teterina N, Bloom ME, Grabowski JM, Mlera L, Nagata BM, Moore I, Martens C, Amaro-Carambot E, Lamirande EW, Whitehead SS, Pletnev AG. Routes of Zika virus dissemination in the testis and epididymis of immunodeficient mice. Nature Communications. 9: 5350. PMID 30559387 DOI: 10.1038/S41467-018-07782-X  0.631
2018 Bustos-Arriaga J, Gromowski GD, Tsetsarkin KA, Firestone CY, Castro-Jiménez T, Pletnev AG, Cedillo-Barrón L, Whitehead SS. Decreased accumulation of subgenomic RNA in human cells infected with vaccine candidate DEN4Δ30 increases viral susceptibility to type I interferon. Vaccine. PMID 29752023 DOI: 10.1016/J.Vaccine.2018.04.087  0.487
2017 Grabowski JM, Tsetsarkin KA, Long D, Scott DP, Rosenke R, Schwan TG, Mlera L, Offerdahl DK, Pletnev AG, Bloom ME. Flavivirus Infection of Ixodes scapularis (Black-Legged Tick) Ex Vivo Organotypic Cultures and Applications for Disease Control. Mbio. 8. PMID 28830948 DOI: 10.1128/Mbio.01255-17  0.598
2017 Tsetsarkin KA, Liu G, Volkova E, Pletnev AG. Synergistic Internal Ribosome Entry Site/MicroRNA-Based Approach for Flavivirus Attenuation and Live Vaccine Development. Mbio. 8. PMID 28420742 DOI: 10.1128/Mbio.02326-16  0.43
2016 Tsetsarkin KA, Liu G, Kenney H, Hermance M, Thangamani S, Pletnev AG. Concurrent micro-RNA mediated silencing of tick-borne flavivirus replication in tick vector and in the brain of vertebrate host. Scientific Reports. 6: 33088. PMID 27620807 DOI: 10.1038/Srep33088  0.549
2016 Tsetsarkin KA, Kenney H, Chen R, Liu G, Manukyan H, Whitehead SS, Laassri M, Chumakov K, Pletnev AG. A Full-Length Infectious cDNA Clone of Zika Virus from the 2015 Epidemic in Brazil as a Genetic Platform for Studies of Virus-Host Interactions and Vaccine Development. Mbio. 7. PMID 27555311 DOI: 10.1128/Mbio.01114-16  0.606
2016 Tsetsarkin KA, Chen R, Weaver SC. Interspecies transmission and chikungunya virus emergence. Current Opinion in Virology. 16: 143-150. PMID 26986235 DOI: 10.1016/J.Coviro.2016.02.007  0.614
2016 Tsetsarkin KA, Liu G, Shen K, Pletnev AG. Kissing-loop interaction between 5' and 3' ends of tick-borne Langat virus genome 'bridges the gap' between mosquito- and tick-borne flaviviruses in mechanisms of viral RNA cyclization: applications for virus attenuation and vaccine development. Nucleic Acids Research. PMID 26850640 DOI: 10.1093/Nar/Gkw061  0.462
2015 Tsetsarkin KA, Liu G, Kenney H, Bustos-Arriaga J, Hanson CT, Whitehead SS, Pletnev AG. Dual miRNA targeting restricts host range and attenuates neurovirulence of flaviviruses. Plos Pathogens. 11: e1004852. PMID 25906260 DOI: 10.1371/Journal.Ppat.1004852  0.546
2014 Weise WJ, Hermance ME, Forrester N, Adams AP, Langsjoen R, Gorchakov R, Wang E, Alcorn MD, Tsetsarkin K, Weaver SC. A novel live-attenuated vaccine candidate for mayaro Fever. Plos Neglected Tropical Diseases. 8: e2969. PMID 25101995 DOI: 10.1371/Journal.Pntd.0002969  0.468
2014 Tsetsarkin KA, Chen R, Yun R, Rossi SL, Plante KS, Guerbois M, Forrester N, Perng GC, Sreekumar E, Leal G, Huang J, Mukhopadhyay S, Weaver SC. Multi-peaked adaptive landscape for chikungunya virus evolution predicts continued fitness optimization in Aedes albopictus mosquitoes. Nature Communications. 5: 4084. PMID 24933611 DOI: 10.1038/Ncomms5084  0.436
2013 Chen R, Wang E, Tsetsarkin KA, Weaver SC. Chikungunya virus 3' untranslated region: adaptation to mosquitoes and a population bottleneck as major evolutionary forces. Plos Pathogens. 9: e1003591. PMID 24009512 DOI: 10.1371/Journal.Ppat.1003591  0.495
2013 Tsetsarkin KA, Sampson-Johannes A, Sawyer L, Kinsey J, Higgs S, Vanlandingham DL. Photochemical inactivation of chikungunya virus in human apheresis platelet components by amotosalen and UVA light. The American Journal of Tropical Medicine and Hygiene. 88: 1163-9. PMID 23530077 DOI: 10.4269/Ajtmh.12-0603  0.646
2013 Coffey LL, Forrester N, Tsetsarkin K, Vasilakis N, Weaver SC. Factors shaping the adaptive landscape for arboviruses: implications for the emergence of disease. Future Microbiology. 8: 155-76. PMID 23374123 DOI: 10.2217/Fmb.12.139  0.41
2011 Tsetsarkin KA, Weaver SC. Sequential adaptive mutations enhance efficient vector switching by Chikungunya virus and its epidemic emergence. Plos Pathogens. 7: e1002412. PMID 22174678 DOI: 10.1371/Journal.Ppat.1002412  0.542
2011 Tsetsarkin KA, Chen R, Sherman MB, Weaver SC. Chikungunya virus: evolution and genetic determinants of emergence. Current Opinion in Virology. 1: 310-7. PMID 21966353 DOI: 10.1016/J.Coviro.2011.07.004  0.607
2011 Plante K, Wang E, Partidos CD, Weger J, Gorchakov R, Tsetsarkin K, Borland EM, Powers AM, Seymour R, Stinchcomb DT, Osorio JE, Frolov I, Weaver SC. Novel chikungunya vaccine candidate with an IRES-based attenuation and host range alteration mechanism. Plos Pathogens. 7: e1002142. PMID 21829348 DOI: 10.1371/Journal.Ppat.1002142  0.523
2011 McGee CE, Tsetsarkin KA, Guy B, Lang J, Plante K, Vanlandingham DL, Higgs S. Stability of yellow fever virus under recombinatory pressure as compared with chikungunya virus. Plos One. 6: e23247. PMID 21826243 DOI: 10.1371/Journal.Pone.0023247  0.839
2011 Tsetsarkin KA, McGee CE, Higgs S. Chikungunya virus adaptation to Aedes albopictus mosquitoes does not correlate with acquisition of cholesterol dependence or decreased pH threshold for fusion reaction. Virology Journal. 8: 376. PMID 21801412 DOI: 10.1186/1743-422X-8-376  0.793
2011 Tsetsarkin KA, Chen R, Leal G, Forrester N, Higgs S, Huang J, Weaver SC. Chikungunya virus emergence is constrained in Asia by lineage-specific adaptive landscapes. Proceedings of the National Academy of Sciences of the United States of America. 108: 7872-7. PMID 21518887 DOI: 10.1073/Pnas.1018344108  0.67
2011 Volk SM, Chen R, Tsetsarkin KA, Adams AP, Garcia TI, Sall AA, Nasar F, Schuh AJ, Holmes EC, Higgs S, Maharaj PD, Brault AC, Weaver SC. Author's correction: Genome-scale phylogenetic analyses of chikungunya virus reveal independent emergences of recent epidemics and various evolutionary rates Journal of Virology. 85: 5706. DOI: 10.1128/Jvi.00628-11  0.601
2010 Volk SM, Chen R, Tsetsarkin KA, Adams AP, Garcia TI, Sall AA, Nasar F, Schuh AJ, Holmes EC, Higgs S, Maharaj PD, Brault AC, Weaver SC. Genome-scale phylogenetic analyses of chikungunya virus reveal independent emergences of recent epidemics and various evolutionary rates. Journal of Virology. 84: 6497-504. PMID 20410280 DOI: 10.1128/Jvi.01603-09  0.636
2010 McGee CE, Shustov AV, Tsetsarkin K, Frolov IV, Mason PW, Vanlandingham DL, Higgs S. Infection, dissemination, and transmission of a West Nile virus green fluorescent protein infectious clone by Culex pipiens quinquefasciatus mosquitoes. Vector Borne and Zoonotic Diseases (Larchmont, N.Y.). 10: 267-74. PMID 19619041 DOI: 10.1089/Vbz.2009.0067  0.821
2009 Tsetsarkin KA, McGee CE, Volk SM, Vanlandingham DL, Weaver SC, Higgs S. Epistatic roles of E2 glycoprotein mutations in adaption of chikungunya virus to Aedes albopictus and Ae. aegypti mosquitoes. Plos One. 4: e6835. PMID 19718263 DOI: 10.1371/Journal.Pone.0006835  0.783
2008 McElroy KL, Girard YA, McGee CE, Tsetsarkin KA, Vanlandingham DL, Higgs S. Characterization of the antigen distribution and tissue tropisms of three phenotypically distinct yellow fever virus variants in orally infected Aedes aegypti mosquitoes. Vector Borne and Zoonotic Diseases (Larchmont, N.Y.). 8: 675-87. PMID 18494601 DOI: 10.1089/Vbz.2007.0269  0.788
2008 McGee CE, Tsetsarkin K, Vanlandingham DL, McElroy KL, Lang J, Guy B, Decelle T, Higgs S. Substitution of wild-type yellow fever asibi sequences for 17D vaccine sequences in ChimeriVax-Dengue 4 does not enhance infection of Aedes aegypti mosquitoes Journal of Infectious Diseases. 197: 686-692. PMID 18266608 DOI: 10.1086/527328  0.814
2008 McGee CE, Lewis MG, St. Claire M, Wagner W, Lang J, Guy B, Tsetsarkin K, Higgs S, Decelle T. Recombinant chimeric virus with wild-type dengue 4 virus premembrane and envelope and virulent yellow fever virus Asibi backbone sequences is dramatically attenuated in nonhuman primates Journal of Infectious Diseases. 197: 693-697. PMID 18266603 DOI: 10.1086/527329  0.801
2007 Tsetsarkin KA, Vanlandingham DL, McGee CE, Higgs S. A single mutation in chikungunya virus affects vector specificity and epidemic potential Plos Pathogens. 3: e201. PMID 18069894 DOI: 10.1371/Journal.Ppat.0030201  0.805
2007 Sim C, Hong YS, Tsetsarkin KA, Vanlandingham DL, Higgs S, Collins FH. Anopheles gambiae heat shock protein cognate 70B impedes o'nyong-nyong virus replication. Bmc Genomics. 8: 231. PMID 17625007 DOI: 10.1186/1471-2164-8-231  0.659
2006 Tsetsarkin K, Higgs S, McGee CE, De Lamballerie X, Charrel RN, Vanlandingham DL. Infectious clones of Chikungunya virus (La Réunion isolate) for vector competence studies. Vector Borne and Zoonotic Diseases (Larchmont, N.Y.). 6: 325-37. PMID 17187566 DOI: 10.1089/Vbz.2006.6.325  0.842
2006 McElroy KL, Tsetsarkin KA, Vanlandingham DL, Higgs S. Manipulation of the yellow fever virus non-structural genes 2A and 4B and the 3'non-coding region to evaluate genetic determinants of viral dissemination from the Aedes aegypti midgut. The American Journal of Tropical Medicine and Hygiene. 75: 1158-64. PMID 17172386 DOI: 10.4269/Ajtmh.2006.75.1158  0.82
2006 McElroy KL, Tsetsarkin KA, Vanlandingham DL, Higgs S. Role of the yellow fever virus structural protein genes in viral dissemination from the Aedes aegypti mosquito midgut. The Journal of General Virology. 87: 2993-3001. PMID 16963758 DOI: 10.1099/Vir.0.82023-0  0.843
2006 Vanlandingham DL, Tsetsarkin K, Klingler KA, Hong C, McElroy KL, Lehane MJ, Higgs S. Determinants of vector specificity of o'nyong nyong and chikungunya viruses in Anopheles and Aedes mosquitoes. The American Journal of Tropical Medicine and Hygiene. 74: 663-9. PMID 16607002 DOI: 10.4269/Ajtmh.2006.74.663  0.851
2005 Vanlandingham DL, Tsetsarkin K, Hong C, Klingler K, McElroy KL, Lehane MJ, Higgs S. Development and characterization of a double subgenomic chikungunya virus infectious clone to express heterologous genes in Aedes aegypti mosquitoes. Insect Biochemistry and Molecular Biology. 35: 1162-70. PMID 16102421 DOI: 10.1016/J.Ibmb.2005.05.008  0.827
2005 McElroy KL, Tsetsarkin KA, Vanlandingham DL, Higgs S. Characterization of an infectious clone of the wild-type yellow fever virus Asibi strain that is able to infect and disseminate in mosquitoes. The Journal of General Virology. 86: 1747-51. PMID 15914853 DOI: 10.1099/Vir.0.80746-0  0.853
2005 Vanlandingham DL, Hong C, Klingler K, Tsetsarkin K, McElroy KL, Powers AM, Lehane MJ, Higgs S. Differential infectivities of o'nyong-nyong and chikungunya virus isolates in Anopheles gambiae and Aedes aegypti mosquitoes. The American Journal of Tropical Medicine and Hygiene. 72: 616-21. PMID 15891138 DOI: 10.4269/Ajtmh.2005.72.616  0.836
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