| Year |
Citation |
Score |
| 2024 |
Balthazar JT, Golparian D, Unemo M, Read TD, Grosse M, Stadler M, Pfarr K, Schiefer A, Hoerauf A, Edwards JL, Vassylyev DG, Shafer WM. A laboratory-based predictive pathway for the development of high-level resistance to corallopyronin A, an inhibitor of bacterial RNA polymerase. Microbiology Spectrum. e0056024. PMID 38647280 DOI: 10.1128/spectrum.00560-24 |
0.414 |
|
| 2023 |
Golparian D, Jacobsson S, Holley CL, Shafer WM, Unemo M. High-level in vitro resistance to gentamicin acquired in a stepwise manner in Neisseria gonorrhoeae. The Journal of Antimicrobial Chemotherapy. PMID 37253051 DOI: 10.1093/jac/dkad168 |
0.375 |
|
| 2022 |
Lyu M, Ayala JC, Chirakos I, Su CC, Shafer WM, Yu EW. Structural Basis of Peptide-Based Antimicrobial Inhibition of a Resistance-Nodulation-Cell Division Multidrug Efflux Pump. Microbiology Spectrum. e0299022. PMID 36121287 DOI: 10.1128/spectrum.02990-22 |
0.331 |
|
| 2022 |
Edwards JL, Balthazar JT, Esposito DLA, Ayala JC, Schiefer A, Pfarr K, Hoerauf A, Alt S, Hesterkamp T, Grosse M, Stadler M, Golparian D, Unemo M, Read TD, Shafer WM. Potent and Anti-Gonococcal Activity of the RpoB Inhibitor Corallopyronin A. Msphere. e0036222. PMID 36094073 DOI: 10.1128/msphere.00362-22 |
0.375 |
|
| 2022 |
Ayala JC, Balthazar JT, Shafer WM. Transcriptional regulation of the efflux pump operon: importance for antimicrobial resistance. Microbiology (Reading, England). 168. PMID 35916832 DOI: 10.1099/mic.0.001231 |
0.394 |
|
| 2022 |
Holley CL, Dhulipala V, Balthazar JT, Le Van A, Begum AA, Chen SC, Read TD, Matoga M, Hoffman IF, Golparian D, Unemo M, Jerse AE, Shafer WM. A Single Amino Acid Substitution in Elongation Factor G Can Confer Low-Level Gentamicin Resistance in . Antimicrobial Agents and Chemotherapy. 66: e0025122. PMID 35465683 DOI: 10.1128/aac.00251-22 |
0.404 |
|
| 2022 |
Ayala JC, Schmerer MW, Kersh EN, Unemo M, Shafer WM. Gonococcal Clinical Strains Bearing a Common Single Nucleotide Polymorphism That Results in Enhanced Expression of the Virulence Gene Frequently Possess a Promoter Mutation That Decreases Antibiotic Susceptibility. Mbio. e0027622. PMID 35258329 DOI: 10.1128/mbio.00276-22 |
0.459 |
|
| 2021 |
Beggs GA, Ayala JC, Kavanaugh LG, Read TD, Hooks GM, Schumacher MA, Shafer WM, Brennan RG. Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations. Nucleic Acids Research. PMID 33784401 DOI: 10.1093/nar/gkab213 |
0.353 |
|
| 2020 |
Ferreyra C, Osborn J, Moussy F, Alirol E, Lahra M, Whiley D, Shafer W, Unemo M, Klausner J, Kelly Cirino C, Wi T. Developing target product profiles for Neisseria gonorrhoeae diagnostics in the context of antimicrobial resistance: An expert consensus. Plos One. 15: e0237424. PMID 32870912 DOI: 10.1371/Journal.Pone.0237424 |
0.35 |
|
| 2020 |
Holley CL, Ayala JC, Shafer WM. Transcriptional control of the gonococcal ompA gene by the MisR/MisS two-component regulatory system. Scientific Reports. 10: 9425. PMID 32523077 DOI: 10.1038/S41598-020-66382-2 |
0.466 |
|
| 2020 |
Lyu M, Moseng MA, Reimche JL, Holley CL, Dhulipala V, Su CC, Shafer WM, Yu EW. Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance. Mbio. 11. PMID 32457251 DOI: 10.1128/Mbio.00996-20 |
0.479 |
|
| 2020 |
Zughaier SM, Rouquette-Loughlin CE, Shafer WM. Identification of a Histone Deacetylase: Epigenetic Impact on Host Gene Expression. Pathogens (Basel, Switzerland). 9. PMID 32085531 DOI: 10.3390/Pathogens9020132 |
0.386 |
|
| 2020 |
Golparian D, Harris SR, Sánchez-Busó L, Hoffmann S, Shafer WM, Bentley SD, Jensen JS, Unemo M. Genomic evolution of Neisseria gonorrhoeae since the preantibiotic era (1928-2013): antimicrobial use/misuse selects for resistance and drives evolution. Bmc Genomics. 21: 116. PMID 32013864 DOI: 10.1186/S12864-020-6511-6 |
0.451 |
|
| 2019 |
Ayala JC, Shafer WM. Transcriptional regulation of a gonococcal gene encoding a virulence factor (L-lactate permease). Plos Pathogens. 15: e1008233. PMID 31860664 DOI: 10.1371/Journal.Ppat.1008233 |
0.452 |
|
| 2019 |
Chen S, Connolly KL, Rouquette-Loughlin C, D'Andrea A, Jerse AE, Shafer WM. Could Dampening Expression of the Neisseria gonorrhoeae -Encoded Efflux Pump Be a Strategy To Preserve Currently or Resurrect Formerly Used Antibiotics To Treat Gonorrhea? Mbio. 10. PMID 31409679 DOI: 10.1128/Mbio.01576-19 |
0.511 |
|
| 2019 |
Beggs GA, Zalucki YM, Brown NG, Rastegari S, Phillips RK, Palzkill T, Shafer W, Kumaraswami M, Brennan RG. Structural, biochemical and characterization of MtrR-mediated resistance to innate antimicrobials by the human pathogen . Journal of Bacteriology. PMID 31331979 DOI: 10.1128/Jb.00401-19 |
0.453 |
|
| 2019 |
Thomas JC, Seby S, Abrams AJ, Cartee J, Lucking S, Vidyaprakash E, Schmerer M, Pham CD, Hong J, Torrone E, St Cyr S, Shafer WM, Bernstein K, Kersh EN, Gernert KM, et al. Evidence of Recent Genomic Evolution in Gonococcal Strains with Decreased Susceptibility to Cephalosporins or Azithromycin in the United States, 2014-2016. The Journal of Infectious Diseases. PMID 30788502 DOI: 10.1093/Infdis/Jiz079 |
0.355 |
|
| 2018 |
Rouquette-Loughlin CE, Reimche JL, Balthazar JT, Dhulipala V, Gernert KM, Kersh EN, Pham CD, Pettus K, Abrams AJ, Trees DL, St Cyr S, Shafer WM. Mechanistic Basis for Decreased Antimicrobial Susceptibility in a Clinical Isolate of Neisseria gonorrhoeae Possessing a Mosaic-Like Efflux Pump Locus. Mbio. 9. PMID 30482834 DOI: 10.1128/Mbio.02281-18 |
0.56 |
|
| 2018 |
Cristillo AD, Bristow CC, Torrone E, Dillon JA, Kirkcaldy RD, Dong H, Grad YH, Nicholas RA, Rice PA, Lawrence K, Oldach D, Shafer WM, Zhou P, Wi TE, Morris SR, et al. Antimicrobial Resistance in Neisseria gonorrhoeae: Proceedings of the STAR Sexually Transmitted Infection-Clinical Trial Group Programmatic Meeting. Sexually Transmitted Diseases. PMID 30363025 DOI: 10.1097/Olq.0000000000000929 |
0.383 |
|
| 2018 |
Shafer WM. Mosaic Drug Efflux Gene Sequences from Commensal Can Lead to Low-Level Azithromycin Resistance Expressed by Clinical Isolates. Mbio. 9. PMID 30206175 DOI: 10.1128/Mbio.01747-18 |
0.524 |
|
| 2018 |
Kahler CM, Nawrocki KL, Anandan A, Vrielink A, Shafer WM. Structure-Function Relationships of the Neisserial EptA Enzyme Responsible for Phosphoethanolamine Decoration of Lipid A: Rationale for Drug Targeting. Frontiers in Microbiology. 9: 1922. PMID 30186254 DOI: 10.3389/Fmicb.2018.01922 |
0.353 |
|
| 2018 |
Rouquette-Loughlin CE, Dhulipala V, Reimche JL, Raterman E, Begum AA, Jerse AE, Shafer WM. - and -acting factors influence expression of the -encoded efflux pump of and levels of gonococcal susceptibility to substrate antimicrobials. Antimicrobial Agents and Chemotherapy. PMID 29891604 DOI: 10.1128/Aac.00821-18 |
0.474 |
|
| 2017 |
Djoko KY, Achard MES, Phan MD, Lo AW, Miraula M, Prombhul S, Hancock SJ, Peters KM, Sidjabat H, Harris PN, Mitić N, Walsh TR, Anderson GJ, Shafer WM, Paterson DL, et al. Copper ions and coordination complexes as novel carbapenem adjuvants. Antimicrobial Agents and Chemotherapy. PMID 29133551 DOI: 10.1128/Aac.02280-17 |
0.367 |
|
| 2017 |
Rice PA, Shafer WM, Ram S, Jerse AE. Neisseria gonorrhoeae: Drug Resistance, Mouse Models, and Vaccine Development. Annual Review of Microbiology. 71: 665-686. PMID 28886683 DOI: 10.1146/Annurev-Micro-090816-093530 |
0.411 |
|
| 2017 |
Alirol E, Wi TE, Bala M, Bazzo ML, Chen XS, Deal C, Dillon JR, Kularatne R, Heim J, Hooft van Huijsduijnen R, Hook EW, Lahra MM, Lewis DA, Ndowa F, Shafer WM, et al. Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines. Plos Medicine. 14: e1002366. PMID 28746372 DOI: 10.1371/Journal.Pmed.1002366 |
0.321 |
|
| 2017 |
Rouquette-Loughlin CE, Zalucki YM, Dhulipala VL, Balthazar JT, Doyle RG, Nicholas RA, Begum AA, Raterman EL, Jerse AE, Shafer WM. Control of gdhR Expression in Neisseria gonorrhoeae via Autoregulation and a Master Repressor (MtrR) of a Drug Efflux Pump Operon. Mbio. 8. PMID 28400529 DOI: 10.1128/Mbio.00449-17 |
0.492 |
|
| 2017 |
Vidyaprakash E, Abrams AJ, Shafer WM, Trees DL. Whole genome sequencing of a large panel of contemporary Neisseria gonorrhoeae clinical isolates indicates that a wild-type mtrA gene is common: implications for inducible antimicrobial resistance. Antimicrobial Agents and Chemotherapy. PMID 28193667 DOI: 10.1128/Aac.00262-17 |
0.47 |
|
| 2017 |
Sc C, Zugnhaier S, Unemo M, Shafer W. P1.11 Dampening of the mtrcde efflux pump operon in neisseria gonorrhoeae strain ho41 enhances gonococcal susceptibility to penicillin Sexually Transmitted Infections. 93. DOI: 10.1136/Sextrans-2017-053264.119 |
0.529 |
|
| 2016 |
Kandler JL, Acevedo RV, Dickinson MK, Cash DR, Shafer WM, Nau Cornelissen C. The genes that encode the gonococcal transferrin binding proteins, tbpB and tbpA, are differentially regulated by MisR under iron-replete and iron-depleted conditions. Molecular Microbiology. PMID 27353397 DOI: 10.1111/Mmi.13450 |
0.35 |
|
| 2016 |
Unemo M, Del Rio C, Shafer WM. Antimicrobial Resistance Expressed by Neisseria gonorrhoeae: A Major Global Public Health Problem in the 21st Century. Microbiology Spectrum. 4. PMID 27337478 DOI: 10.1128/Microbiolspec.Ei10-0009-2015 |
0.441 |
|
| 2016 |
Kandler JL, Holley CL, Reimche JL, Dhulipala V, Balthazar JT, Muszyński A, Carlson RW, Shafer WM. The MisR response regulator is necessary for intrinsic cationic antimicrobial peptide and aminoglycoside resistance in Neisseria gonorrhoeae. Antimicrobial Agents and Chemotherapy. PMID 27216061 DOI: 10.1128/Aac.00823-16 |
0.506 |
|
| 2015 |
Foerster S, Golparian D, Jacobsson S, Hathaway LJ, Low N, Shafer WM, Althaus CL, Unemo M. Genetic Resistance Determinants, In Vitro Time-Kill Curve Analysis and Pharmacodynamic Functions for the Novel Topoisomerase II Inhibitor ETX0914 (AZD0914) in Neisseria gonorrhoeae. Frontiers in Microbiology. 6: 1377. PMID 26696986 DOI: 10.3389/Fmicb.2015.01377 |
0.469 |
|
| 2015 |
Zughaier SM, Kandler JL, Balthazar JT, Shafer WM. Phosphoethanolamine Modification of Neisseria gonorrhoeae Lipid A Reduces Autophagy Flux in Macrophages. Plos One. 10: e0144347. PMID 26641098 DOI: 10.1371/Journal.Pone.0144347 |
0.337 |
|
| 2015 |
Goytia M, Hawel L, Dhulipala VL, Joseph SJ, Read TD, Shafer WM. Characterization of a spermine/spermidine transport system reveals a novel DNA sequence duplication in Neisseria gonorrhoeae. Fems Microbiology Letters. 362. PMID 26229069 DOI: 10.1093/Femsle/Fnv125 |
0.431 |
|
| 2015 |
Johnson PJ, Shafer WM. The Transcriptional Repressor, MtrR, of the mtrCDE Efflux Pump Operon of Neisseria gonorrhoeae Can Also Serve as an Activator of "off Target" Gene (glnE) Expression. Antibiotics (Basel, Switzerland). 4: 188-197. PMID 26078871 DOI: 10.3390/Antibiotics4020188 |
0.406 |
|
| 2015 |
Su CC, Bolla JR, Kumar N, Radhakrishnan A, Long F, Delmar JA, Chou TH, Rajashankar KR, Shafer WM, Yu EW. Structure and function of Neisseria gonorrhoeae MtrF illuminates a class of antimetabolite efflux pumps. Cell Reports. 11: 61-70. PMID 25818299 DOI: 10.1016/J.Celrep.2015.03.003 |
0.414 |
|
| 2015 |
Ezewudo MN, Joseph SJ, Castillo-Ramirez S, Dean D, Del Rio C, Didelot X, Dillon JA, Selden RF, Shafer WM, Turingan RS, Unemo M, Read TD. Population structure of Neisseria gonorrhoeae based on whole genome data and its relationship with antibiotic resistance. Peerj. 3: e806. PMID 25780762 DOI: 10.7717/Peerj.806 |
0.442 |
|
| 2015 |
Bauer ME, Shafer WM. On the in vivo significance of bacterial resistance to antimicrobial peptides. Biochimica Et Biophysica Acta. PMID 25701234 DOI: 10.1016/J.Bbamem.2015.02.012 |
0.423 |
|
| 2015 |
Ohneck EA, Goytia M, Rouquette-Loughlin CE, Joseph SJ, Read TD, Jerse AE, Shafer WM. Overproduction of the MtrCDE efflux pump in Neisseria gonorrhoeae produces unexpected changes in cellular transcription patterns. Antimicrobial Agents and Chemotherapy. 59: 724-6. PMID 25367915 DOI: 10.1128/Aac.04148-14 |
0.797 |
|
| 2015 |
Shafer W. S11.2 Efflux pumps inneisseria gonorrhoeae– cause of resistance and targets for therapeutics and vaccine? Sexually Transmitted Infections. 91: A18.2-A18. DOI: 10.1136/Sextrans-2015-052270.58 |
0.506 |
|
| 2014 |
Unemo M, Shafer WM. Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future. Clinical Microbiology Reviews. 27: 587-613. PMID 24982323 DOI: 10.1128/Cmr.00010-14 |
0.459 |
|
| 2014 |
Bolla JR, Su CC, Do SV, Radhakrishnan A, Kumar N, Long F, Chou TH, Delmar JA, Lei HT, Rajashankar KR, Shafer WM, Yu EW. Crystal structure of the Neisseria gonorrhoeae MtrD inner membrane multidrug efflux pump. Plos One. 9: e97903. PMID 24901477 DOI: 10.1371/Journal.Pone.0097903 |
0.449 |
|
| 2014 |
Lei HT, Chou TH, Su CC, Bolla JR, Kumar N, Radhakrishnan A, Long F, Delmar JA, Do SV, Rajashankar KR, Shafer WM, Yu EW. Crystal structure of the open state of the Neisseria gonorrhoeae MtrE outer membrane channel. Plos One. 9: e97475. PMID 24901251 DOI: 10.1371/Journal.Pone.0097475 |
0.39 |
|
| 2014 |
Vélez Acevedo RN, Ronpirin C, Kandler JL, Shafer WM, Cornelissen CN. Identification of regulatory elements that control expression of the tbpBA operon in Neisseria gonorrhoeae. Journal of Bacteriology. 196: 2762-74. PMID 24837286 DOI: 10.1128/Jb.01693-14 |
0.377 |
|
| 2014 |
Kandler JL, Joseph SJ, Balthazar JT, Dhulipala V, Read TD, Jerse AE, Shafer WM. Phase-variable expression of lptA modulates the resistance of Neisseria gonorrhoeae to cationic antimicrobial peptides. Antimicrobial Agents and Chemotherapy. 58: 4230-3. PMID 24820072 DOI: 10.1128/Aac.03108-14 |
0.491 |
|
| 2014 |
Golparian D, Shafer WM, Ohnishi M, Unemo M. Importance of multidrug efflux pumps in the antimicrobial resistance property of clinical multidrug-resistant isolates of Neisseria gonorrhoeae. Antimicrobial Agents and Chemotherapy. 58: 3556-9. PMID 24733458 DOI: 10.1128/Aac.00038-14 |
0.472 |
|
| 2014 |
Unemo M, Golparian D, Shafer WM. Challenges with gonorrhea in the era of multi-drug and extensively drug resistance - are we on the right track? Expert Review of Anti-Infective Therapy. 12: 653-6. PMID 24702589 DOI: 10.1586/14787210.2014.906902 |
0.41 |
|
| 2014 |
Packiam M, Yedery RD, Begum AA, Carlson RW, Ganguly J, Sempowski GD, Ventevogel MS, Shafer WM, Jerse AE. Phosphoethanolamine decoration of Neisseria gonorrhoeae lipid A plays a dual immunostimulatory and protective role during experimental genital tract infection. Infection and Immunity. 82: 2170-9. PMID 24686069 DOI: 10.1128/Iai.01504-14 |
0.379 |
|
| 2014 |
Zughaier SM, Kandler JL, Shafer WM. Neisseria gonorrhoeae modulates iron-limiting innate immune defenses in macrophages. Plos One. 9: e87688. PMID 24489950 DOI: 10.1371/Journal.Pone.0087688 |
0.315 |
|
| 2013 |
Hobbs MM, Anderson JE, Balthazar JT, Kandler JL, Carlson RW, Ganguly J, Begum AA, Duncan JA, Lin JT, Sparling PF, Jerse AE, Shafer WM. Lipid A's structure mediates Neisseria gonorrhoeae fitness during experimental infection of mice and men. Mbio. 4: e00892-13. PMID 24255126 DOI: 10.1128/Mbio.00892-13 |
0.312 |
|
| 2013 |
Goytia M, Dhulipala VL, Shafer WM. Spermine impairs biofilm formation by Neisseria gonorrhoeae. Fems Microbiology Letters. 343: 64-9. PMID 23506248 DOI: 10.1111/1574-6968.12130 |
0.329 |
|
| 2013 |
Cloward JM, Shafer WM. MtrR control of a transcriptional regulatory pathway in Neisseria meningitidis that influences expression of a gene (nadA) encoding a vaccine candidate. Plos One. 8: e56097. PMID 23409129 DOI: 10.1371/Journal.Pone.0056097 |
0.376 |
|
| 2013 |
Lewis LA, Shafer WM, Dutta Ray T, Ram S, Rice PA. Phosphoethanolamine residues on the lipid A moiety of Neisseria gonorrhoeae lipooligosaccharide modulate binding of complement inhibitors and resistance to complement killing. Infection and Immunity. 81: 33-42. PMID 23071134 DOI: 10.1128/Iai.00751-12 |
0.428 |
|
| 2012 |
Zalucki YM, Dhulipala V, Shafer WM. Dueling regulatory properties of a transcriptional activator (MtrA) and repressor (MtrR) that control efflux pump gene expression in Neisseria gonorrhoeae. Mbio. 3: e00446-12. PMID 23221802 DOI: 10.1128/Mbio.00446-12 |
0.396 |
|
| 2012 |
Kunz AN, Begum AA, Wu H, D'Ambrozio JA, Robinson JM, Shafer WM, Bash MC, Jerse AE. Impact of fluoroquinolone resistance mutations on gonococcal fitness and in vivo selection for compensatory mutations. The Journal of Infectious Diseases. 205: 1821-9. PMID 22492860 DOI: 10.1093/Infdis/Jis277 |
0.441 |
|
| 2012 |
Mercante AD, Jackson L, Johnson PJ, Stringer VA, Dyer DW, Shafer WM. MpeR regulates the mtr efflux locus in Neisseria gonorrhoeae and modulates antimicrobial resistance by an iron-responsive mechanism. Antimicrobial Agents and Chemotherapy. 56: 1491-501. PMID 22214775 DOI: 10.1128/Aac.06112-11 |
0.424 |
|
| 2011 |
Unemo M, Shafer WM. Antibiotic resistance in Neisseria gonorrhoeae: origin, evolution, and lessons learned for the future. Annals of the New York Academy of Sciences. 1230: E19-28. PMID 22239555 DOI: 10.1111/J.1749-6632.2011.06215.X |
0.443 |
|
| 2011 |
Hollander A, Mercante AD, Shafer WM, Cornelissen CN. The iron-repressed, AraC-like regulator MpeR activates expression of fetA in Neisseria gonorrhoeae. Infection and Immunity. 79: 4764-76. PMID 21947770 DOI: 10.1128/Iai.05806-11 |
0.386 |
|
| 2011 |
Ohneck EA, Zalucki YM, Johnson PJ, Dhulipala V, Golparian D, Unemo M, Jerse AE, Shafer WM. A novel mechanism of high-level, broad-spectrum antibiotic resistance caused by a single base pair change in Neisseria gonorrhoeae. Mbio. 2. PMID 21933917 DOI: 10.1128/Mbio.00187-11 |
0.821 |
|
| 2011 |
Balthazar JT, Gusa A, Martin LE, Choudhury B, Carlson R, Shafer WM. Lipooligosaccharide Structure is an Important Determinant in the Resistance of Neisseria Gonorrhoeae to Antimicrobial Agents of Innate Host Defense. Frontiers in Microbiology. 2: 30. PMID 21747781 DOI: 10.3389/Fmicb.2011.00030 |
0.501 |
|
| 2011 |
Hobbs MM, Sparling PF, Cohen MS, Shafer WM, Deal CD, Jerse AE. Experimental Gonococcal Infection in Male Volunteers: Cumulative Experience with Neisseria gonorrhoeae Strains FA1090 and MS11mkC. Frontiers in Microbiology. 2: 123. PMID 21734909 DOI: 10.3389/Fmicb.2011.00123 |
0.346 |
|
| 2011 |
Zalucki YM, Shafer WM, Jennings MP. Directed evolution of efficient secretion in the SRP-dependent export of TolB. Biochimica Et Biophysica Acta. 1808: 2544-50. PMID 21699884 DOI: 10.1016/J.Bbamem.2011.06.004 |
0.328 |
|
| 2011 |
Routh MD, Zalucki Y, Su CC, Zhang Q, Shafer WM, Yu EW. Efflux pumps of the resistance-nodulation-division family: a perspective of their structure, function, and regulation in gram-negative bacteria. Advances in Enzymology and Related Areas of Molecular Biology. 77: 109-46. PMID 21692368 DOI: 10.1002/9780470920541.Ch3 |
0.481 |
|
| 2011 |
Shafer WM, Ohneck EA. Taking the gonococcus-human relationship to a whole new level: implications for the coevolution of microbes and humans. Mbio. 2: e00067-11. PMID 21521723 DOI: 10.1128/Mbio.00067-11 |
0.764 |
|
| 2011 |
Johnson PJ, Stringer VA, Shafer WM. Off-target gene regulation mediated by transcriptional repressors of antimicrobial efflux pump genes in Neisseria gonorrhoeae. Antimicrobial Agents and Chemotherapy. 55: 2559-65. PMID 21422217 DOI: 10.1128/Aac.00010-11 |
0.456 |
|
| 2010 |
Zähner D, Zhou X, Chancey ST, Pohl J, Shafer WM, Stephens DS. Human antimicrobial peptide LL-37 induces MefE/Mel-mediated macrolide resistance in Streptococcus pneumoniae. Antimicrobial Agents and Chemotherapy. 54: 3516-9. PMID 20498319 DOI: 10.1128/Aac.01756-09 |
0.438 |
|
| 2010 |
Goytia M, Shafer WM. Polyamines can increase resistance of Neisseria gonorrhoeae to mediators of the innate human host defense. Infection and Immunity. 78: 3187-95. PMID 20439477 DOI: 10.1128/Iai.01301-09 |
0.448 |
|
| 2010 |
Duval BD, Mathew A, Satola SW, Shafer WM. Altered growth, pigmentation, and antimicrobial susceptibility properties of Staphylococcus aureus due to loss of the major cold shock gene cspB. Antimicrobial Agents and Chemotherapy. 54: 2283-90. PMID 20368405 DOI: 10.1128/Aac.01786-09 |
0.796 |
|
| 2010 |
Kamal N, Shafer WM. Biologic activities of the TolC-like protein of Neisseria meningitidis as assessed by functional complementation in Escherichia coli. Antimicrobial Agents and Chemotherapy. 54: 506-8. PMID 19884363 DOI: 10.1128/Aac.01168-09 |
0.733 |
|
| 2009 |
Lewis LA, Choudhury B, Balthazar JT, Martin LE, Ram S, Rice PA, Stephens DS, Carlson R, Shafer WM. Phosphoethanolamine substitution of lipid A and resistance of Neisseria gonorrhoeae to cationic antimicrobial peptides and complement-mediated killing by normal human serum. Infection and Immunity. 77: 1112-20. PMID 19114544 DOI: 10.1128/Iai.01280-08 |
0.475 |
|
| 2009 |
Folster JP, Johnson PJ, Jackson L, Dhulipali V, Dyer DW, Shafer WM. MtrR modulates rpoH expression and levels of antimicrobial resistance in Neisseria gonorrhoeae. Journal of Bacteriology. 191: 287-97. PMID 18978065 DOI: 10.1128/Jb.01165-08 |
0.497 |
|
| 2008 |
Warner DM, Shafer WM, Jerse AE. Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitness. Molecular Microbiology. 70: 462-78. PMID 18761689 DOI: 10.1111/J.1365-2958.2008.06424.X |
0.54 |
|
| 2008 |
Long F, Rouquette-Loughlin C, Shafer WM, Yu EW. Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli. Antimicrobial Agents and Chemotherapy. 52: 3052-60. PMID 18591276 DOI: 10.1128/Aac.00475-08 |
0.467 |
|
| 2008 |
Garvin LE, Bash MC, Keys C, Warner DM, Ram S, Shafer WM, Jerse AE. Phenotypic and genotypic analyses of Neisseria gonorrhoeae isolates that express frequently recovered PorB PIA variable region types suggest that certain P1a porin sequences confer a selective advantage for urogenital tract infection. Infection and Immunity. 76: 3700-9. PMID 18541655 DOI: 10.1128/Iai.00265-08 |
0.466 |
|
| 2007 |
Warner DM, Folster JP, Shafer WM, Jerse AE. Regulation of the MtrC-MtrD-MtrE efflux-pump system modulates the in vivo fitness of Neisseria gonorrhoeae. The Journal of Infectious Diseases. 196: 1804-12. PMID 18190261 DOI: 10.1086/522964 |
0.471 |
|
| 2007 |
Kamal N, Rouquette-Loughlin C, Shafer WM. The TolC-like protein of neisseria meningitidis is required for extracellular production of the repeats-in-toxin toxin FrpC but not for resistance to antimicrobials recognized by the Mtr efflux pump system. Infection and Immunity. 75: 6008-12. PMID 17923520 DOI: 10.1128/Iai.01995-06 |
0.668 |
|
| 2007 |
Friedrich A, Arvidson CG, Shafer WM, Lee EH, So M. Two ABC transporter operons and the antimicrobial resistance gene mtrF are pilT responsive in Neisseria gonorrhoeae. Journal of Bacteriology. 189: 5399-402. PMID 17496077 DOI: 10.1128/Jb.00300-07 |
0.426 |
|
| 2007 |
Folster JP, Dhulipala V, Nicholas RA, Shafer WM. Differential regulation of ponA and pilMNOPQ expression by the MtrR transcriptional regulatory protein in Neisseria gonorrhoeae. Journal of Bacteriology. 189: 4569-77. PMID 17483228 DOI: 10.1128/Jb.00286-07 |
0.547 |
|
| 2007 |
Lewis L, Ram S, Balthazar J, Martin L, Tzeng Y, Stephens D, Rice P, Shafer W. Gonococcal lipooligosaccharide phosphoethanolamine substitutions modulate serum resistance and C4bp binding Molecular Immunology. 44: 204-205. DOI: 10.1016/J.Molimm.2006.07.135 |
0.371 |
|
| 2006 |
Lee EH, Hill SA, Napier R, Shafer WM. Integration Host Factor is required for FarR repression of the farAB-encoded efflux pump of Neisseria gonorrhoeae. Molecular Microbiology. 60: 1381-400. PMID 16796676 DOI: 10.1111/J.1365-2958.2006.05185.X |
0.342 |
|
| 2006 |
Shafer WM, Folster JP. Towards an understanding of chromosomally mediated penicillin resistance in Neisseria gonorrhoeae: evidence for a porin-efflux pump collaboration. Journal of Bacteriology. 188: 2297-9. PMID 16547015 DOI: 10.1128/Jb.188.7.2297-2299.2006 |
0.465 |
|
| 2005 |
Katzif S, Lee EH, Law AB, Tzeng YL, Shafer WM. CspA regulates pigment production in Staphylococcus aureus through a SigB-dependent mechanism. Journal of Bacteriology. 187: 8181-4. PMID 16291691 DOI: 10.1128/Jb.187.23.8181-8184.2005 |
0.424 |
|
| 2005 |
Rouquette-Loughlin CE, Balthazar JT, Shafer WM. Characterization of the MacA-MacB efflux system in Neisseria gonorrhoeae. The Journal of Antimicrobial Chemotherapy. 56: 856-60. PMID 16162665 DOI: 10.1093/Jac/Dki333 |
0.401 |
|
| 2005 |
Tzeng YL, Ambrose KD, Zughaier S, Zhou X, Miller YK, Shafer WM, Stephens DS. Cationic antimicrobial peptide resistance in Neisseria meningitidis. Journal of Bacteriology. 187: 5387-96. PMID 16030233 DOI: 10.1128/Jb.187.15.5387-5396.2005 |
0.528 |
|
| 2005 |
Rasmussen AW, Alexander HL, Perkins-Balding D, Shafer WM, Stojiljkovic I. Resistance of neisseria meningitidis to the toxic effects of heme iron and other hydrophobic agents requires expression of ght. Journal of Bacteriology. 187: 5214-23. PMID 16030215 DOI: 10.1128/Jb.187.15.5214-5223.2005 |
0.484 |
|
| 2005 |
Hoffmann KM, Williams D, Shafer WM, Brennan RG. Characterization of the multiple transferable resistance repressor, MtrR, from Neisseria gonorrhoeae. Journal of Bacteriology. 187: 5008-12. PMID 15995218 DOI: 10.1128/Jb.187.14.5008-5012.2005 |
0.392 |
|
| 2005 |
Folster JP, Shafer WM. Regulation of mtrF expression in Neisseria gonorrhoeae and its role in high-level antimicrobial resistance. Journal of Bacteriology. 187: 3713-20. PMID 15901695 DOI: 10.1128/Jb.187.11.3713-3720.2005 |
0.522 |
|
| 2004 |
Sieprawska-Lupa M, Mydel P, Krawczyk K, Wójcik K, Puklo M, Lupa B, Suder P, Silberring J, Reed M, Pohl J, Shafer W, McAleese F, Foster T, Travis J, Potempa J. Degradation of human antimicrobial peptide LL-37 by Staphylococcus aureus-derived proteinases. Antimicrobial Agents and Chemotherapy. 48: 4673-9. PMID 15561843 DOI: 10.1128/Aac.48.12.4673-4679.2004 |
0.375 |
|
| 2004 |
Bozja J, Yi K, Shafer WM, Stojiljkovic I. Porphyrin-based compounds exert antibacterial action against the sexually transmitted pathogens Neisseria gonorrhoeae and Haemophilus ducreyi International Journal of Antimicrobial Agents. 24: 578-584. PMID 15555881 DOI: 10.1016/J.Ijantimicag.2004.06.008 |
0.349 |
|
| 2004 |
Rouquette-Loughlin CE, Balthazar JT, Hill SA, Shafer WM. Modulation of the mtrCDE-encoded efflux pump gene complex of Neisseria meningitidis due to a Correia element insertion sequence. Molecular Microbiology. 54: 731-41. PMID 15491363 DOI: 10.1111/J.1365-2958.2004.04299.X |
0.446 |
|
| 2004 |
Rivera-Marrero CA, Stewart J, Shafer WM, Roman J. The down-regulation of cathepsin G in THP-1 monocytes after infection with Mycobacterium tuberculosis is associated with increased intracellular survival of bacilli. Infection and Immunity. 72: 5712-21. PMID 15385470 DOI: 10.1128/Iai.72.10.5712-5721.2004 |
0.305 |
|
| 2004 |
Chen CJ, Tobiason DM, Thomas CE, Shafer WM, Seifert HS, Sparling PF. A mutant form of the Neisseria gonorrhoeae pilus secretin protein PilQ allows increased entry of heme and antimicrobial compounds. Journal of Bacteriology. 186: 730-9. PMID 14729699 DOI: 10.1128/Jb.186.3.730-739.2004 |
0.389 |
|
| 2003 |
Cox DL, Sun Y, Liu H, Lehrer RI, Shafer WM. Susceptibility of Treponema pallidum to host-derived antimicrobial peptides. Peptides. 24: 1741-6. PMID 15019205 DOI: 10.1016/J.Peptides.2003.07.026 |
0.31 |
|
| 2003 |
Lee EH, Rouquette-Loughlin C, Folster JP, Shafer WM. FarR Regulates the farAB-Encoded Efflux Pump of Neisseria gonorrhoeae via an MtrR Regulatory Mechanism Journal of Bacteriology. 185: 7145-7152. PMID 14645274 DOI: 10.1128/Jb.185.24.7145-7152.2003 |
0.392 |
|
| 2003 |
Jerse AE, Sharma ND, Simms AN, Crow ET, Snyder LA, Shafer WM. A gonococcal efflux pump system enhances bacterial survival in a female mouse model of genital tract infection. Infection and Immunity. 71: 5576-82. PMID 14500476 DOI: 10.1128/Iai.71.10.5576-5582.2003 |
0.395 |
|
| 2003 |
Katzif S, Danavall D, Bowers S, Balthazar JT, Shafer WM. The major cold shock gene, cspA, is involved in the susceptibility of Staphylococcus aureus to an antimicrobial peptide of human cathepsin G. Infection and Immunity. 71: 4304-12. PMID 12874306 DOI: 10.1128/Iai.71.8.4304-4312.2003 |
0.499 |
|
| 2003 |
Rouquette-Loughlin C, Dunham SA, Kuhn M, Balthazar JT, Shafer WM. The NorM efflux pump of Neisseria gonorrhoeae and Neisseria meningitidis recognizes antimicrobial cationic compounds. Journal of Bacteriology. 185: 1101-6. PMID 12533487 DOI: 10.1128/Jb.185.3.1101-1106.2003 |
0.452 |
|
| 2003 |
Snyder LA, Shafer WM, Saunders NJ. Divergence and transcriptional analysis of the division cell wall (dcw) gene cluster in Neisseria spp. Molecular Microbiology. 47: 431-42. PMID 12519193 DOI: 10.1046/J.1365-2958.2003.03204.X |
0.358 |
|
| 2003 |
Veal WL, Shafer WM. Identification of a cell envelope protein (MtrF) involved in hydrophobic antimicrobial resistance in Neisseria gonorrhoeae. The Journal of Antimicrobial Chemotherapy. 51: 27-37. PMID 12493784 DOI: 10.1093/Jac/Dkg031 |
0.821 |
|
| 2002 |
Veal WL, Nicholas RA, Shafer WM. Overexpression of the MtrC-MtrD-MtrE efflux pump due to an mtrR mutation is required for chromosomally mediated penicillin resistance in Neisseria gonorrhoeae. Journal of Bacteriology. 184: 5619-24. PMID 12270819 DOI: 10.1128/Jb.184.20.5619-5624.2002 |
0.808 |
|
| 2002 |
Shafer WM, Datta A, Kolli VS, Rahman MM, Balthazar JT, Martin LE, Veal WL, Stephens DS, Carlson R. Phase variable changes in genes lgtA and lgtC within the lgtABCDE operon of Neisseria gonorrhoeae can modulate gonococcal susceptibility to normal human serum. Journal of Endotoxin Research. 8: 47-58. PMID 11981445 DOI: 10.1177/09680519020080010501 |
0.751 |
|
| 2002 |
Rouquette-Loughlin C, Stojiljkovic I, Hrobowski T, Balthazar JT, Shafer WM. Inducible, but not constitutive, resistance of gonococci to hydrophobic agents due to the MtrC-MtrD-MtrE efflux pump requires TonB-ExbB-ExbD proteins. Antimicrobial Agents and Chemotherapy. 46: 561-5. PMID 11796379 DOI: 10.1128/Aac.46.2.561-565.2002 |
0.474 |
|
| 2001 |
Zarantonelli L, Borthagaray G, Lee EH, Veal W, Shafer WM. Decreased susceptibility to azithromycin and erythromycin mediated by a novel mtr(R) promoter mutation in Neisseria gonorrhoeae. The Journal of Antimicrobial Chemotherapy. 47: 651-4. PMID 11328778 DOI: 10.1093/Jac/47.5.651 |
0.787 |
|
| 2001 |
Shafer WM, Veal WL, Lee EH, Zarantonelli L, Balthazar JT, Rouquette C. Genetic organization and regulation of antimicrobial efflux systems possessed by Neisseria gonorrhoeae and Neisseria meningitidis. Journal of Molecular Microbiology and Biotechnology. 3: 219-24. PMID 11321577 |
0.783 |
|
| 2001 |
Snyder LA, Saunders NJ, Shafer WM. A putatively phase variable gene (dca) required for natural competence in Neisseria gonorrhoeae but not Neisseria meningitidis is located within the division cell wall (dcw) gene cluster. Journal of Bacteriology. 183: 1233-41. PMID 11157935 DOI: 10.1128/Jb.183.4.1233-1241.2001 |
0.448 |
|
| 2000 |
Xia M, Whittington WL, Shafer WM, Holmes KK. Gonorrhea among men who have sex with men: outbreak caused by a single genotype of erythromycin-resistant Neisseria gonorrhoeae with a single-base pair deletion in the mtrR promoter region. The Journal of Infectious Diseases. 181: 2080-2. PMID 10837198 DOI: 10.1086/315510 |
0.39 |
|
| 1999 |
Zarantonelli L, Borthagaray G, Lee EH, Shafer WM. Decreased azithromycin susceptibility of Neisseria gonorrhoeae due to mtrR mutations. Antimicrobial Agents and Chemotherapy. 43: 2468-72. PMID 10508026 DOI: 10.1128/Aac.43.10.2468 |
0.559 |
|
| 1999 |
Fallon MT, Shafer W, Jacob E. Use of Cefazolin Microspheres to Treat Localized Methicillin-Resistant Staphylococcus aureus Infections in Rats Journal of Surgical Research. 86: 97-102. PMID 10452874 DOI: 10.1006/Jsre.1999.5686 |
0.351 |
|
| 1999 |
Lee EH, Shafer WM. The farAB-encoded efflux pump mediates resistance of gonococci to long-chained antibacterial fatty acids. Molecular Microbiology. 33: 839-45. PMID 10447892 DOI: 10.1046/J.1365-2958.1999.01530.X |
0.517 |
|
| 1999 |
Rouquette C, Harmon JB, Shafer WM. Induction of the mtrCDE-encoded efflux pump system of Neisseria gonorrhoeae requires MtrA, an AraC-like protein. Molecular Microbiology. 33: 651-8. PMID 10417654 DOI: 10.1046/J.1365-2958.1999.01517.X |
0.527 |
|
| 1998 |
Veal WL, Yellen A, Balthazar JT, Pan W, Spratt BG, Shafer WM. Loss-of-function mutations in the mtr efflux system of Neisseria gonorrhoeae. Microbiology (Reading, England). 144: 621-7. PMID 9534233 DOI: 10.1099/00221287-144-3-621 |
0.805 |
|
| 1998 |
Shafer WM, Qu X, Waring AJ, Lehrer RI. Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family. Proceedings of the National Academy of Sciences of the United States of America. 95: 1829-33. PMID 9465102 DOI: 10.1073/Pnas.95.4.1829 |
0.366 |
|
| 1997 |
Hagman KE, Lucas CE, Balthazar JT, Snyder L, Nilles M, Judd RC, Shafer WM. The MtrD protein of Neisseria gonorrhoeae is a member of the resistance/nodulation/division protein family constituting part of an efflux system. Microbiology (Reading, England). 143: 2117-2125. PMID 27259279 DOI: 10.1099/00221287-143-7-2117 |
0.321 |
|
| 1997 |
Hagman KE, Lucas CE, Balthazar JT, Snyder L, Nilles M, Judd RC, Shafer WM. The MtrD protein of Neisseria gonorrhoeae is a member of the resistance/nodulation/division protein family constituting part of an efflux system. Microbiology (Reading, England). 143: 2117-2125. PMID 27235097 DOI: 10.1099/00221287-143-7-2117 |
0.321 |
|
| 1997 |
Delahay RM, Robertson BD, Balthazar JT, Shafer WM, Ison CA. Involvement of the gonococcal MtrE protein in the resistance of Neisseria gonorrhoeae to toxic hydrophobic agents. Microbiology (Reading, England). 2127-33. PMID 9245802 DOI: 10.1099/00221287-143-7-2127 |
0.446 |
|
| 1997 |
Hagman KE, Lucas CE, Balthazar JT, Snyder L, Nilles M, Judd RC, Shafer WM. The MtrD protein of Neisseria gonorrhoeae is a member of the resistance/nodulation/division protein family constituting part of an efflux system. Microbiology (Reading, England). 143: 2117-25. PMID 9245801 DOI: 10.1099/00221287-143-7-2117 |
0.432 |
|
| 1997 |
Lucas CE, Balthazar JT, Hagman KE, Shafer WM. The MtrR repressor binds the DNA sequence between the mtrR and mtrC genes of Neisseria gonorrhoeae. Journal of Bacteriology. 179: 4123-8. PMID 9209024 DOI: 10.1128/Jb.179.13.4123-4128.1997 |
0.497 |
|
| 1996 |
Swartley JS, Balthazar JT, Coleman J, Shafer WM, Stephens DS. Membrane glycerophospholipid biosynthesis in Neisseria meningitidis and Neisseria gonorrhoeae: identification, characterization, and mutagenesis of a lysophosphatidic acid acyltransferase. Molecular Microbiology. 18: 401-12. PMID 8748025 DOI: 10.1111/J.1365-2958.1995.Mmi_18030401.X |
0.427 |
|
| 1996 |
Qu XD, Harwig SS, Oren AM, Shafer WM, Lehrer RI. Susceptibility of Neisseria gonorrhoeae to protegrins. Infection and Immunity. 64: 1240-5. PMID 8606085 DOI: 10.1128/iai.64.4.1240-1245.1996 |
0.355 |
|
| 1995 |
Hagman KE, Pan W, Spratt BG, Balthazar JT, Judd RC, Shafer WM. Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system. Microbiology (Reading, England). 141: 611-622. PMID 27259881 DOI: 10.1099/13500872-141-3-611 |
0.537 |
|
| 1995 |
Shafer WM, Balthazar JT, Hagman KE, Morse SA. Missense mutations that alter the DNA-binding domain of the MtrR protein occur frequently in rectal isolates of Neisseria gonorrhoeae that are resistant to faecal lipids. Microbiology (Reading, England). 141: 907-11. PMID 7773394 DOI: 10.1099/13500872-141-4-907 |
0.529 |
|
| 1995 |
Hagman KE, Shafer WM. Transcriptional control of the mtr efflux system of Neisseria gonorrhoeae. Journal of Bacteriology. 177: 4162-5. PMID 7608095 DOI: 10.1128/Jb.177.14.4162-4165.1995 |
0.499 |
|
| 1995 |
Lucas CE, Hagman KE, Levin JC, Stein DC, Shafer WM. Importance of lipooligosaccharide structure in determining gonococcal resistance to hydrophobic antimicrobial agents resulting from the mtr efflux system. Molecular Microbiology. 16: 1001-9. PMID 7476176 DOI: 10.1111/J.1365-2958.1995.Tb02325.X |
0.584 |
|
| 1993 |
Shafer WM, Shepherd ME, Boltin B, Wells L, Pohl J. Synthetic peptides of human lysosomal cathepsin G with potent antipseudomonal activity. Infection and Immunity. 61: 1900-8. PMID 8478079 DOI: 10.1128/Iai.61.5.1900-1908.1993 |
0.303 |
|
| 1991 |
Shafer WM, Onunka VC, Jannoun M, Huthwaite LW. Molecular mechanism for the antigonococcal action of lysosomal cathepsin G. Molecular Microbiology. 4: 1269-77. PMID 2126324 DOI: 10.1111/J.1365-2958.1990.Tb00706.X |
0.33 |
|
| 1991 |
Shafer WM, Judd RC. Gonococcal penicillin-binding protein 3 and the surface-exposed 44kDa peptidoglycan-binding protein appear to be the same molecule. Molecular Microbiology. 5: 1097-103. PMID 1956287 DOI: 10.1111/J.1365-2958.1991.Tb01882.X |
0.337 |
|
| 1990 |
Shafer WM, Onunka VC. Mechanism of staphylococcal resistance to non-oxidative antimicrobial action of neutrophils: importance of pH and ionic strength in determining the bactericidal action of cathepsin G. Journal of General Microbiology. 135: 825-30. PMID 2600586 DOI: 10.1099/00221287-135-4-825 |
0.34 |
|
| 1989 |
Judd RC, Shafer WM. Topographical alterations in proteins I of Neisseria gonorrhoeae correlated with lipooligosaccharide variation. Molecular Microbiology. 3: 637-43. PMID 2503681 DOI: 10.1111/J.1365-2958.1989.Tb00211.X |
0.31 |
|
| 1988 |
Farley MM, Shafer WM, Spitznagel JK. Lipopolysaccharide structure determines ionic and hydrophobic binding of a cationic antimicrobial neutrophil granule protein. Infection and Immunity. 56: 1589-92. PMID 3286500 DOI: 10.1128/Iai.56.6.1589-1592.1988 |
0.356 |
|
| 1988 |
Shafer WM, Engle SA, Martin LE, Spitznagel JK. Killing of Proteus mirabilis by polymorphonuclear leukocyte granule proteins: evidence for species specificity by antimicrobial proteins. Infection and Immunity. 56: 51-3. PMID 3275586 DOI: 10.1128/Iai.56.1.51-53.1988 |
0.341 |
|
| 1988 |
Shafer WM. Lipopolysaccharide masking of gonococcal outer-membrane proteins modulates binding of bacterial cathepsin G to gonococci. Journal of General Microbiology. 134: 539-45. PMID 3141568 DOI: 10.1099/00221287-134-3-539 |
0.309 |
|
| 1988 |
Stephens DS, Shafer WM. Evidence that the serum resistance genetic locus sac-3 of Neisseria gonorrhoeae is involved in lipopolysaccharide structure. Journal of General Microbiology. 133: 2671-8. PMID 3129537 DOI: 10.1099/00221287-133-9-2671 |
0.37 |
|
| 1988 |
Ray C, Igo M, Shafer W, Losick R, Moran CP. Suppression of ctc promoter mutations in Bacillus subtilis Journal of Bacteriology. 170: 900-907. PMID 3123466 DOI: 10.1128/Jb.170.2.900-907.1988 |
0.38 |
|
| 1988 |
Spitznagel JK, Shafer WM, Farley MM. A Mutation in Salmonella Typhimurium that Enhances Resistance to Oxygen-Independent Antimicrobial Neutrophil Protein Advances in Experimental Medicine and Biology. 239: 79-88. DOI: 10.1007/978-3-642-85718-8_23 |
0.486 |
|
| 1987 |
Farley MM, Shafer WM, Spitznagel JK. Antimicrobial binding of a radiolabeled cationic neutrophil granule protein. Infection and Immunity. 55: 1536-9. PMID 3553007 DOI: 10.1128/Iai.55.6.1536-1539.1987 |
0.375 |
|
| 1987 |
Shafer WM, Morse SA. Cleavage of the protein III and major iron-regulated protein of Neisseria gonorrhoeae by lysosomal cathepsin G. Journal of General Microbiology. 133: 155-62. PMID 3116158 DOI: 10.1099/00221287-133-1-155 |
0.366 |
|
| 1986 |
Shafer WM, Onunka VC, Martin LE. Antigonococcal activity of human neutrophil cathepsin G Infection and Immunity. 54: 184-188. PMID 3093384 DOI: 10.1128/Iai.54.1.184-188.1986 |
0.347 |
|
| 1986 |
Shafer WM, Onunka V, Hitchcock PJ. A spontaneous mutant of Neisseria gonorrhoeae with decreased resistance to neutrophil granule proteins. The Journal of Infectious Diseases. 153: 910-7. PMID 3084666 DOI: 10.1093/infdis/153.5.910 |
0.385 |
|
| 1985 |
Spitznagel JK, Shafer WM. Neutrophil killing of bacteria by oxygen-independent mechanisms: a historical summary. Reviews of Infectious Diseases. 7: 398-403. PMID 3895354 DOI: 10.1093/Clinids/7.3.398 |
0.33 |
|
| 1984 |
Shafer WM, Guymon LF, Lind I, Sparling PF. Identification of an envelope mutation (env-10) resulting in increased antibiotic susceptibility and pyocin resistance in a clinical isolate of Neisseria gonorrhoeae. Antimicrobial Agents and Chemotherapy. 25: 767-9. PMID 6430226 DOI: 10.1128/AAC.25.6.767 |
0.352 |
|
| 1984 |
Shafer WM, Martin LE, Spitznagel JK. Cationic antimicrobial proteins isolated from human neutrophil granulocytes in the presence of diisopropyl fluorophosphate. Infection and Immunity. 45: 29-35. PMID 6376359 DOI: 10.1128/Iai.45.1.29-35.1984 |
0.415 |
|
| 1979 |
Shafer WM, Iandolo JJ. Genetics of staphylococcal enterotoxin B in methicillin-resistant isolates of Staphylococcus aureus. Infection and Immunity. 25: 902-11. PMID 259057 DOI: 10.1128/Iai.25.3.902-911.1979 |
0.484 |
|
| 1978 |
Shafer WM, Iandolo JJ. Chromosomal locus for staphylococcal enterotoxin B. Infection and Immunity. 20: 273-8. PMID 669796 |
0.377 |
|
| Show low-probability matches. |