Jason P. Gigley, Ph.D. - Publications

Affiliations: 
2007 Immunology and Microbiology Dartmouth College, Hanover, NH, United States 
Area:
Microbiology Biology, Parasitology Biology

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Donley DW, Realing M, Gigley JP, Fox JH. Iron activates microglia and directly stimulates indoleamine-2,3-dioxygenase activity in the N171-82Q mouse model of Huntington's disease. Plos One. 16: e0250606. PMID 33989290 DOI: 10.1371/journal.pone.0250606  1
2020 Ivanova DL, Krempels R, Denton SL, Fettel KD, Saltz GM, Rach D, Fatima R, Mundhenke T, Materi J, Dunay IR, Gigley JP. NK Cells Negatively Regulate CD8 T Cells to Promote Immune Exhaustion and Chronic Infection. Frontiers in Cellular and Infection Microbiology. 10: 313. PMID 32733814 DOI: 10.3389/fcimb.2020.00313  1
2019 Ivanova DL, Mundhenke TM, Gigley JP. The IL-12- and IL-23-Dependent NK Cell Response Is Essential for Protective Immunity against Secondary Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 31604804 DOI: 10.4049/jimmunol.1801525  0.01
2019 Ivanova DL, Denton SL, Fettel KD, Sondgeroth KS, Munoz Gutierrez J, Bangoura B, Dunay IR, Gigley JP. Innate Lymphoid Cells in Protection, Pathology, and Adaptive Immunity During Apicomplexan Infection. Frontiers in Immunology. 10: 196. PMID 30873151 DOI: 10.3389/fimmu.2019.00196  0.01
2018 Parker KD, Albeke SE, Gigley JP, Goldstein AM, Ward NL. Microbiome Composition in Both Wild-Type and Disease Model Mice Is Heavily Influenced by Mouse Facility. Frontiers in Microbiology. 9: 1598. PMID 30079054 DOI: 10.3389/Fmicb.2018.01598  0.01
2016 Parker KD, Gigley JP, Ward NL. Paths to GI Research in the Wild West: Tales From Wyoming. Cellular and Molecular Gastroenterology and Hepatology. 2: 560-562. PMID 28174736 DOI: 10.1016/J.Jcmgh.2016.06.001  0.01
2016 Ivanova DL, Fatima R, Gigley JP. Comparative Analysis of Conventional Natural Killer Cell Responses to Acute Infection with Toxoplasma gondii Strains of Different Virulence. Frontiers in Immunology. 7: 347. PMID 27721814 DOI: 10.3389/fimmu.2016.00347  0.01
2016 Donley DW, Olson AR, Raisbeck MF, Fox JH, Gigley JP. Huntingtons Disease Mice Infected with Toxoplasma gondii Demonstrate Early Kynurenine Pathway Activation, Altered CD8+ T-Cell Responses, and Premature Mortality. Plos One. 11: e0162404. PMID 27611938 DOI: 10.1371/Journal.Pone.0162404  1
2016 Gigley JP. The Diverse Role of NK Cells in Immunity to Toxoplasma gondii Infection. Plos Pathogens. 12: e1005396. PMID 26915066 DOI: 10.1371/journal.ppat.1005396  1
2014 Ivanova D, Krempels R, Ryfe J, Weitzman K, Stephenson D, Gigley JP. NK cells in mucosal defense against infection. Biomed Research International. 2014: 413982. PMID 25197644 DOI: 10.1155/2014/413982  1
2012 Gigley JP, Bhadra R, Moretto MM, Khan IA. T cell exhaustion in protozoan disease. Trends in Parasitology. 28: 377-84. PMID 22832368 DOI: 10.1016/j.pt.2012.07.001  1
2012 Bhadra R, Gigley JP, Khan IA. PD-1-mediated attrition of polyfunctional memory CD8+ T cells in chronic toxoplasma infection. The Journal of Infectious Diseases. 206: 125-34. PMID 22539813 DOI: 10.1093/infdis/jis304  1
2011 Bhadra R, Gigley JP, Khan IA. Cutting edge: CD40-CD40 ligand pathway plays a critical CD8-intrinsic and -extrinsic role during rescue of exhausted CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 4421-5. PMID 21949017 DOI: 10.4049/jimmunol.1102319  1
2011 Gigley JP, Khan IA. Plasmacytoid DC from aged mice down-regulate CD8 T cell responses by inhibiting cDC maturation after Encephalitozoon cuniculi infection. Plos One. 6: e20838. PMID 21695169 DOI: 10.1371/journal.pone.0020838  1
2011 Gigley JP, Bhadra R, Khan IA. CD8 T Cells and Toxoplasma gondii: A New Paradigm. Journal of Parasitology Research. 2011: 243796. PMID 21687650 DOI: 10.1155/2011/243796  1
2011 Bhadra R, Gigley JP, Khan IA. The CD8 T-cell road to immunotherapy of toxoplasmosis. Immunotherapy. 3: 789-801. PMID 21668315 DOI: 10.2217/imt.11.68  1
2011 Bhadra R, Gigley JP, Weiss LM, Khan IA. Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade. Proceedings of the National Academy of Sciences of the United States of America. 108: 9196-201. PMID 21576466 DOI: 10.1073/Pnas.1015298108  1
2011 Fox BA, Falla A, Rommereim LM, Tomita T, Gigley JP, Mercier C, Cesbron-Delauw MF, Weiss LM, Bzik DJ. Type II Toxoplasma gondii KU80 knockout strains enable functional analysis of genes required for cyst development and latent infection. Eukaryotic Cell. 10: 1193-206. PMID 21531875 DOI: 10.1128/Ec.00297-10  1
2010 Balsley MA, Malesevic M, Stemmy EJ, Gigley J, Jurjus RA, Herzog D, Bukrinsky MI, Fischer G, Constant SL. A cell-impermeable cyclosporine A derivative reduces pathology in a mouse model of allergic lung inflammation. Journal of Immunology (Baltimore, Md. : 1950). 185: 7663-70. PMID 21057089 DOI: 10.4049/Jimmunol.1001707  1
2009 Gigley JP, Fox BA, Bzik DJ. Long-term immunity to lethal acute or chronic type II Toxoplasma gondii infection is effectively induced in genetically susceptible C57BL/6 mice by immunization with an attenuated type I vaccine strain. Infection and Immunity. 77: 5380-8. PMID 19797073 DOI: 10.1128/Iai.00649-09  1
2009 Fox BA, Ristuccia JG, Gigley JP, Bzik DJ. Efficient gene replacements in Toxoplasma gondii strains deficient for nonhomologous end joining. Eukaryotic Cell. 8: 520-9. PMID 19218423 DOI: 10.1128/Ec.00357-08  1
2009 Gigley JP, Fox BA, Bzik DJ. Cell-mediated immunity to Toxoplasma gondii develops primarily by local Th1 host immune responses in the absence of parasite replication. Journal of Immunology (Baltimore, Md. : 1950). 182: 1069-78. PMID 19124750 DOI: 10.4049/Jimmunol.182.2.1069  1
2009 Beaver LM, Stemmy EJ, Constant SL, Schwartz A, Little LG, Gigley JP, Chun G, Sugden KD, Ceryak SM, Patierno SR. Lung injury, inflammation and Akt signaling following inhalation of particulate hexavalent chromium. Toxicology and Applied Pharmacology. 235: 47-56. PMID 19109987 DOI: 10.1016/J.Taap.2008.11.018  1
2007 Guan H, Moretto M, Bzik DJ, Gigley J, Khan IA. NK cells enhance dendritic cell response against parasite antigens via NKG2D pathway. Journal of Immunology (Baltimore, Md. : 1950). 179: 590-6. PMID 17579080 DOI: 10.4049/Jimmunol.179.1.590  1
2006 Combe CL, Moretto MM, Schwartzman JD, Gigley JP, Bzik DJ, Khan IA. Lack of IL-15 results in the suboptimal priming of CD4+ T cell response against an intracellular parasite. Proceedings of the National Academy of Sciences of the United States of America. 103: 6635-40. PMID 16614074 DOI: 10.1073/Pnas.0506180103  1
2004 Fox BA, Gigley JP, Bzik DJ. Toxoplasma gondii lacks the enzymes required for de novo arginine biosynthesis and arginine starvation triggers cyst formation. International Journal For Parasitology. 34: 323-31. PMID 15003493 DOI: 10.1016/J.Ijpara.2003.12.001  1
2001 Gabay C, Marinova-Mutafchieva L, Williams RO, Gigley JP, Butler DM, Feldmann M, Arend WP. Increased production of intracellular interleukin-1 receptor antagonist type I in the synovium of mice with collagen-induced arthritis: a possible role in the resolution of arthritis. Arthritis and Rheumatism. 44: 451-62. PMID 11229477 DOI: 10.1002/1529-0131(200102)44:2<451::AID-ANR64>3.0.CO;2-H  1
1997 Kuhné MR, Robbins M, Hambor JE, Mackey MF, Kosaka Y, Nishimura T, Gigley JP, Noelle RJ, Calderhead DM. Assembly and regulation of the CD40 receptor complex in human B cells. The Journal of Experimental Medicine. 186: 337-42. PMID 9221764 DOI: 10.1084/Jem.186.2.337  1
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