☰

Daniel P. Flaherty, Ph.D. - Publications

Affiliations: 
2015- Purdue University, West Lafayette, IN, United States 
Area:
Pharmaceutical Chemistry, Biochemistry, Organic Chemistry
Tree Info Similar researchers PubMed Report error

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Imhoff RD, Rosenthal MR, Ashraf K, Bhanot P, Ng CL, Flaherty DP. Identification of covalent fragment inhibitors for Plasmodium falciparum UCHL3 with anti-malarial efficacy. Bioorganic & Medicinal Chemistry Letters. 94: 129458. PMID 37634761 DOI: 10.1016/j.bmcl.2023.129458  0.309
2022 Dwyer TS, O'Brien JB, Ptak CP, LaVigne JE, Flaherty DP, Watts VJ, Roman DL. Protein-protein interaction-based high throughput screening for adenylyl cyclase 1 inhibitors: Design, implementation, and discovery of a novel chemotype. Frontiers in Pharmacology. 13: 977742. PMID 36147328 DOI: 10.3389/fphar.2022.977742  0.33
2021 Chojnacki M, Cao X, Flaherty DP, Dunman PM. Optimization of 2-Acylaminocycloalkylthiophene Derivatives for Activity against RnpA. Antibiotics (Basel, Switzerland). 10. PMID 33807357 DOI: 10.3390/antibiotics10040369  0.374
2021 Krabill AD, Chen H, Hussain S, Hewitt CS, Imhoff RD, Muli CS, Das C, Galardy PJ, Wendt MK, Flaherty DP. Optimization and Anti-Cancer Properties of Fluoromethylketones as Covalent Inhibitors for Ubiquitin C-Terminal Hydrolase L1. Molecules (Basel, Switzerland). 26. PMID 33668938 DOI: 10.3390/molecules26051227  0.383
2019 Colquhoun JM, Ha L, Beckley A, Meyers B, Flaherty DP, Dunman PM. Identification of Small Molecule Inhibitors of RnpA. Antibiotics (Basel, Switzerland). 8. PMID 31035380 DOI: 10.3390/Antibiotics8020048  0.361
2017 Flaherty DP, Harris MT, Schroeder CE, Khan H, Kahney E, Hackler A, Patrick S, Weiner WS, Aube J, Sharlow ER, Morris JC, Golden JE. Optimization and Evaluation of Antiparasitic Benzamidobenzoic Acids as Inhibitors of Kinetoplastid Hexokinase 1. Chemmedchem. PMID 29105342 DOI: 10.1002/Cmdc.201700592  0.646
2017 Hackler A, Patrick SL, Kahney EW, Flaherty DP, Sharlow ER, Morris JC, Golden JE. Antiparasitic lethality of sulfonamidebenzamides in kinetoplastids. Bioorganic & Medicinal Chemistry Letters. PMID 28119024 DOI: 10.1016/J.Bmcl.2017.01.043  0.646
2016 Lopez-Sambrooks C, Shrimal S, Khodier C, Flaherty DP, Rinis N, Charest JC, Gao N, Zhao P, Wells L, Lewis TA, Lehrman MA, Gilmore R, Golden JE, Contessa JN. Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells. Nature Chemical Biology. PMID 27694802 DOI: 10.1038/Nchembio.2194  0.626
2014 Flaherty DP, Miller JR, Garshott DM, Hedrick M, Gosalia P, Li Y, Milewski M, Sugarman E, Vasile S, Salaniwal S, Su Y, Smith LH, Chung TD, Pinkerton AB, Aubé J, et al. Discovery of Sulfonamidebenzamides as Selective Apoptotic CHOP Pathway Activators of the Unfolded Protein Response. Acs Medicinal Chemistry Letters. 5: 1278-1283. PMID 25530830 DOI: 10.1021/Ml5003234  0.632
2014 Matharu DS, Flaherty DP, Simpson DS, Schroeder CE, Chung D, Yan D, Noah JW, Jonsson CB, White EL, Aubé J, Plemper RK, Severson WE, Golden JE. Optimization of potent and selective quinazolinediones: inhibitors of respiratory syncytial virus that block RNA-dependent RNA-polymerase complex activity. Journal of Medicinal Chemistry. 57: 10314-28. PMID 25399509 DOI: 10.1021/Jm500902X  0.586
2014 Flaherty DP, Simpson DS, Miller M, Maki BE, Zou B, Shi J, Wu M, McManus OB, Aubé J, Li M, Golden JE. Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold. Bioorganic & Medicinal Chemistry Letters. 24: 3968-73. PMID 25017033 DOI: 10.1016/J.Bmcl.2014.06.032  0.579
2013 Harris MT, Walker DM, Drew ME, Mitchell WG, Dao K, Schroeder CE, Flaherty DP, Weiner WS, Golden JE, Morris JC. Interrogating a hexokinase-selected small-molecule library for inhibitors of Plasmodium falciparum hexokinase. Antimicrobial Agents and Chemotherapy. 57: 3731-7. PMID 23716053 DOI: 10.1128/Aac.00662-13  0.628
2010 Flaherty DP, Kiyota T, Dong Y, Ikezu T, Vennerstrom JL. Phenolic bis-styrylbenzenes as β-amyloid binding ligands and free radical scavengers. Journal of Medicinal Chemistry. 53: 7992-9. PMID 21038854 DOI: 10.1021/Jm1006929  0.494
2007 Flaherty DP, Walsh SM, Kiyota T, Dong Y, Ikezu T, Vennerstrom JL. Polyfluorinated bis-styrylbenzene beta-amyloid plaque binding ligands. Journal of Medicinal Chemistry. 50: 4986-92. PMID 17845017 DOI: 10.1021/Jm070085F  0.477
Show low-probability matches.