Yosef Shaul - Publications

Affiliations: 
Weizmann Institute of Science, Rehovot, Israel 
Area:
Cell Biology, Molecular Biology, Biochemistry
Website:
http://www.weizmann.ac.il/molgen/Shaul/

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Year Citation  Score
2023 Havkin-Solomon T, Itzhaki E, Joffe N, Reuven N, Shaul Y, Dikstein R. Selective translational control of cellular and viral mRNAs by RPS3 mRNA binding. Nucleic Acids Research. PMID 37070189 DOI: 10.1093/nar/gkad269  0.639
2023 Havkin-Solomon T, Fraticelli D, Bahat A, Hayat D, Reuven N, Shaul Y, Dikstein R. Translation regulation of specific mRNAs by RPS26 C-terminal RNA-binding tail integrates energy metabolism and AMPK-mTOR signaling. Nucleic Acids Research. PMID 37013984 DOI: 10.1093/nar/gkad238  0.655
2021 Broennimann K, Ricardo-Lax I, Adler J, Michailidis E, de Jong YP, Reuven N, Shaul Y. RNR-R2 Upregulation by a Short Non-Coding Viral Transcript. Biomolecules. 11. PMID 34944466 DOI: 10.3390/biom11121822  0.324
2021 Tsvetkov P, Adler J, Strobelt R, Adamovich Y, Asher G, Reuven N, Shaul Y. NQO1 Binds and Supports SIRT1 Function. Frontiers in Pharmacology. 12: 671929. PMID 34234670 DOI: 10.3389/fphar.2021.671929  0.569
2020 Tsvetkov P, Myers N, Adler J, Shaul Y. Degradation of Intrinsically Disordered Proteins by the NADH 26S Proteasome. Biomolecules. 10. PMID 33297334 DOI: 10.3390/biom10121642  0.537
2019 Lubelsky Y, Shaul Y. Recruitment of the protein phosphatase-1 catalytic subunit to promoters by the dual-function transcription factor RFX1. Biochemical and Biophysical Research Communications. 509: 1015-1020. PMID 30654936 DOI: 10.1016/J.Bbrc.2019.01.011  0.794
2019 Reuven N, Shanzer M, Shaul Y. Hippo Pathway Regulation by Tyrosine Kinases. Methods in Molecular Biology (Clifton, N.J.). 1893: 215-236. PMID 30565137 DOI: 10.1007/978-1-4939-8910-2_17  0.329
2018 Myers N, Olender T, Savidor A, Levin Y, Reuven N, Shaul Y. The Disordered Landscape of the 20S Proteasome Substrates Reveals Tight Association with Phase Separated Granules. Proteomics. e1800076. PMID 30039638 DOI: 10.1002/Pmic.201800076  0.387
2018 Tsvetkov P, Adler J, Myers N, Biran A, Reuven N, Shaul Y. Oncogenic addiction to high 26S proteasome level. Cell Death & Disease. 9: 773. PMID 29991718 DOI: 10.1038/S41419-018-0806-4  0.573
2017 Shanzer M, Adler J, Ricardo-Lax I, Reuven N, Shaul Y. The nonreceptor tyrosine kinase c-Src attenuates SCF(β-TrCP) E3-ligase activity abrogating Taz proteasomal degradation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28154141 DOI: 10.1073/Pnas.1610223114  0.341
2015 Ricardo-Lax I, Ramanan V, Michailidis E, Shamia T, Reuven N, Rice CM, Shlomai A, Shaul Y. Hepatitis B virus induces RNR-R2 expression via DNA damage response activation. Journal of Hepatology. PMID 26026873 DOI: 10.1016/J.Jhep.2015.05.017  0.677
2015 Reuven N, Adler J, Porat Z, Polonio-Vallon T, Hofmann TG, Shaul Y. The Tyrosine Kinase c-Abl Promotes Homeodomain-interacting Protein Kinase 2 (HIPK2) Accumulation and Activation in Response to DNA Damage. The Journal of Biological Chemistry. 290: 16478-88. PMID 25944899 DOI: 10.1074/Jbc.M114.628982  0.367
2015 Reuven N, Shanzer M, Shaul Y. Tyrosine phosphorylation of WW proteins. Experimental Biology and Medicine (Maywood, N.J.). 240: 375-82. PMID 25627656 DOI: 10.1177/1535370214565991  0.359
2015 Shanzer M, Ricardo-Lax I, Keshet R, Reuven N, Shaul Y. The polyomavirus middle T-antigen oncogene activates the Hippo pathway tumor suppressor Lats in a Src-dependent manner. Oncogene. 34: 4190-8. PMID 25362852 DOI: 10.1038/Onc.2014.347  0.341
2015 Keshet R, Adler J, Ricardo Lax I, Shanzer M, Porat Z, Reuven N, Shaul Y. c-Abl antagonizes the YAP oncogenic function. Cell Death and Differentiation. 22: 935-45. PMID 25361080 DOI: 10.1038/Cdd.2014.182  0.415
2014 Keshet R, Bryansker Kraitshtein Z, Shanzer M, Adler J, Reuven N, Shaul Y. c-Abl tyrosine kinase promotes adipocyte differentiation by targeting PPAR-gamma 2. Proceedings of the National Academy of Sciences of the United States of America. 111: 16365-70. PMID 25368164 DOI: 10.1073/Pnas.1411086111  0.347
2014 Adamovich Y, Adler J, Meltser V, Reuven N, Shaul Y. AMPK couples p73 with p53 in cell fate decision. Cell Death and Differentiation. 21: 1451-9. PMID 24874608 DOI: 10.1038/Cdd.2014.60  0.36
2014 Tsvetkov P, Myers N, Eliav R, Adamovich Y, Hagai T, Adler J, Navon A, Shaul Y. NADH Binds and stabilizes the 26S proteasomes independent of ATP Journal of Biological Chemistry. 289: 11272-11281. PMID 24596095 DOI: 10.1074/Jbc.M113.537175  0.601
2013 Reuven N, Adler J, Meltser V, Shaul Y. The Hippo pathway kinase Lats2 prevents DNA damage-induced apoptosis through inhibition of the tyrosine kinase c-Abl. Cell Death and Differentiation. 20: 1330-40. PMID 23852372 DOI: 10.1038/Cdd.2013.83  0.361
2013 Adamovich Y, Shlomai A, Tsvetkov P, Umansky KB, Reuven N, Estall JL, Spiegelman BM, Shaul Y. The protein level of PGC-1α, a key metabolic regulator, is controlled by NADH-NQO1. Molecular and Cellular Biology. 33: 2603-13. PMID 23648480 DOI: 10.1128/Mcb.01672-12  0.737
2012 Moscovitz O, Tsvetkov P, Hazan N, Michaelevski I, Keisar H, Ben-Nissan G, Shaul Y, Sharon M. A mutually inhibitory feedback loop between the 20S proteasome and its regulator, NQO1. Molecular Cell. 47: 76-86. PMID 22793692 DOI: 10.1016/J.Molcel.2012.05.049  0.623
2012 Tsvetkov P, Shaul Y. Determination of IUP based on susceptibility for degradation by default. Methods in Molecular Biology (Clifton, N.J.). 895: 3-18. PMID 22760308 DOI: 10.1007/978-1-61779-927-3_1  0.581
2012 Tsvetkov P, Myers N, Moscovitz O, Sharon M, Prilusky J, Shaul Y. Thermo-resistant intrinsically disordered proteins are efficient 20S proteasome substrates. Molecular Biosystems. 8: 368-73. PMID 22027891 DOI: 10.1039/C1Mb05283G  0.558
2011 Suskiewicz MJ, Sussman JL, Silman I, Shaul Y. Context-dependent resistance to proteolysis of intrinsically disordered proteins Protein Science. 20: 1285-1297. PMID 21574196 DOI: 10.1002/Pro.657  0.324
2011 Wiggins CM, Tsvetkov P, Johnson M, Joyce CL, Lamb CA, Bryant NJ, Komander D, Shaul Y, Cook SJ. BIM(EL), an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylation. Journal of Cell Science. 124: 969-77. PMID 21378313 DOI: 10.1242/Jcs.058438  0.609
2011 Bar-Yishay I, Shaul Y, Shlomai A. Hepatocyte metabolic signalling pathways and regulation of hepatitis B virus expression. Liver International : Official Journal of the International Association For the Study of the Liver. 31: 282-90. PMID 21281428 DOI: 10.1111/J.1478-3231.2010.02423.X  0.694
2011 Tsvetkov P, Adamovich Y, Elliott E, Shaul Y. E3 ligase STUB1/CHIP regulates NAD(P)H:quinone oxidoreductase 1 (NQO1) accumulation in aged brain, a process impaired in certain Alzheimer disease patients. The Journal of Biological Chemistry. 286: 8839-45. PMID 21220432 DOI: 10.1074/Jbc.M110.193276  0.586
2011 Meltser V, Ben-Yehoyada M, Shaul Y. c-Abl tyrosine kinase in the DNA damage response: cell death and more. Cell Death and Differentiation. 18: 2-4. PMID 21151157 DOI: 10.1038/Cdd.2010.132  0.329
2010 Meltser V, Ben-Yehoyada M, Reuven N, Shaul Y. c-Abl downregulates the slow phase of double-strand break repair. Cell Death & Disease. 1: e20. PMID 21364621 DOI: 10.1038/Cddis.2009.21  0.312
2010 Adler J, Reuven N, Kahana C, Shaul Y. c-Fos proteasomal degradation is activated by a default mechanism, and its regulation by NAD(P)H:quinone oxidoreductase 1 determines c-Fos serum response kinetics. Molecular and Cellular Biology. 30: 3767-78. PMID 20498278 DOI: 10.1128/Mcb.00899-09  0.376
2010 Rechtman MM, Har-Noy O, Bar-Yishay I, Fishman S, Adamovich Y, Shaul Y, Halpern Z, Shlomai A. Curcumin inhibits hepatitis B virus via down-regulation of the metabolic coactivator PGC-1alpha. Febs Letters. 584: 2485-90. PMID 20434445 DOI: 10.1016/J.Febslet.2010.04.067  0.685
2010 Cohen D, Adamovich Y, Reuven N, Shaul Y. Hepatitis B virus activates deoxynucleotide synthesis in nondividing hepatocytes by targeting the R2 gene. Hepatology (Baltimore, Md.). 51: 1538-46. PMID 20155784 DOI: 10.1002/Hep.23519  0.656
2010 Tsvetkov P, Reuven N, Shaul Y. Ubiquitin-independent p53 proteasomal degradation. Cell Death and Differentiation. 17: 103-8. PMID 19557012 DOI: 10.1038/Cdd.2009.67  0.57
2010 Rechtman MM, Har-Noy O, Bar-Yishay I, Fishman S, Adamovich Y, Shaul Y, Halpern Z, Shlomai A. Erratum to “Curcumin inhibits hepatitis B virus via down-regulation of the metabolic coactivator PGC-1α” [FEBS Lett. 584 (2010) 2485-2490] Febs Letters. 584: 3239-3239. DOI: 10.1016/J.Febslet.2010.05.041  0.656
2010 Shaul Y, Tsvetkov P, Reuven N. IDPs and Protein Degradation in the Cell Instrumental Analysis of Intrinsically Disordered Proteins: Assessing Structure and Conformation. 1-36. DOI: 10.1002/9780470602614.ch1  0.561
2009 Tsvetkov P, Reuven N, Shaul Y. The nanny model for IDPs. Nature Chemical Biology. 5: 778-81. PMID 19841623 DOI: 10.1038/Nchembio.233  0.572
2009 Shlomai A, Lubelsky Y, Har-Noy O, Shaul Y. The "Trojan horse" model-delivery of anti-HBV small interfering RNAs by a recombinant HBV vector. Biochemical and Biophysical Research Communications. 390: 619-23. PMID 19818740 DOI: 10.1016/J.Bbrc.2009.10.016  0.771
2009 Tsvetkov P, Reuven N, Prives C, Shaul Y. Susceptibility of p53 unstructured N terminus to 20 S proteasomal degradation programs the stress response. The Journal of Biological Chemistry. 284: 26234-42. PMID 19617345 DOI: 10.1074/Jbc.M109.040493  0.582
2009 Shlomai A, Shaul Y. The metabolic activator FOXO1 binds hepatitis B virus DNA and activates its transcription. Biochemical and Biophysical Research Communications. 381: 544-8. PMID 19233123 DOI: 10.1016/J.Bbrc.2009.02.078  0.686
2008 Levy D, Reuven N, Shaul Y. A regulatory circuit controlling Itch-mediated p73 degradation by Runx. The Journal of Biological Chemistry. 283: 27462-8. PMID 18701449 DOI: 10.1074/Jbc.M803941200  0.42
2008 Sheu JJ, Choi JH, Yildiz I, Tsai FJ, Shaul Y, Wang TL, Shih IeM. The roles of human sucrose nonfermenting protein 2 homologue in the tumor-promoting functions of Rsf-1. Cancer Research. 68: 4050-7. PMID 18519663 DOI: 10.1158/0008-5472.Can-07-3240  0.342
2008 Shlomai A, Shaul Y. The "metabolovirus" model of hepatitis B virus suggests nutritional therapy as an effective anti-viral weapon. Medical Hypotheses. 71: 53-7. PMID 18334285 DOI: 10.1016/J.Mehy.2007.08.032  0.673
2008 Levy D, Adamovich Y, Reuven N, Shaul Y. Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage. Molecular Cell. 29: 350-61. PMID 18280240 DOI: 10.1016/J.Molcel.2007.12.022  0.411
2008 Tsvetkov P, Asher G, Paz A, Reuven N, Sussman JL, Silman I, Shaul Y. Operational definition of intrinsically unstructured protein sequences based on susceptibility to the 20S proteasome Proteins: Structure, Function and Genetics. 70: 1357-1366. PMID 17879262 DOI: 10.1002/Prot.21614  0.578
2007 Levy D, Adamovich Y, Reuven N, Shaul Y. The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73 Cell Death and Differentiation. 14: 743-751. PMID 17110958 DOI: 10.1038/Sj.Cdd.4402063  0.37
2006 Shlomai A, Paran N, Shaul Y. PGC-1alpha controls hepatitis B virus through nutritional signals. Proceedings of the National Academy of Sciences of the United States of America. 103: 16003-8. PMID 17043229 DOI: 10.1073/Pnas.0607837103  0.68
2006 Asher G, Reuven N, Shaul Y. 20S proteasomes and protein degradation "by default". Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 28: 844-9. PMID 16927316 DOI: 10.1002/Bies.20447  0.366
2006 Ketzinel-Gilad M, Shaul Y, Galun E. RNA interference for antiviral therapy. The Journal of Gene Medicine. 8: 933-50. PMID 16779870 DOI: 10.1002/Jgm.929  0.349
2006 Asher G, Dym O, Tsvetkov P, Adler J, Shaul Y. The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol. Biochemistry. 45: 6372-8. PMID 16700548 DOI: 10.1021/Bi0600087  0.586
2005 Lubelsky Y, Reuven N, Shaul Y. Autorepression of rfx1 gene expression: functional conservation from yeast to humans in response to DNA replication arrest. Molecular and Cellular Biology. 25: 10665-73. PMID 16287876 DOI: 10.1128/Mcb.25.23.10665-10673.2005  0.78
2005 Kahana C, Asher G, Shaul Y. Mechanisms of protein degradation: an odyssey with ODC. Cell Cycle (Georgetown, Tex.). 4: 1461-4. PMID 16205122 DOI: 10.4161/Cc.4.11.2115  0.402
2005 Cooper A, Tal G, Lider O, Shaul Y. Cytokine induction by the hepatitis B virus capsid in macrophages is facilitated by membrane heparan sulfate and involves TLR2. Journal of Immunology (Baltimore, Md. : 1950). 175: 3165-76. PMID 16116207 DOI: 10.4049/Jimmunol.175.5.3165  0.374
2005 Asher G, Shaul Y. p53 proteasomal degradation: poly-ubiquitination is not the whole story. Cell Cycle (Georgetown, Tex.). 4: 1015-8. PMID 16082197 DOI: 10.4161/Cc.4.8.1900  0.376
2005 Tsvetkov P, Asher G, Reiss V, Shaul Y, Sachs L, Lotem J. Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin. Proceedings of the National Academy of Sciences of the United States of America. 102: 5535-40. PMID 15809436 DOI: 10.1073/Pnas.0501828102  0.585
2005 Asher G, Bercovich Z, Tsvetkov P, Shaul Y, Kahana C. 20S proteasomal degradation of ornithine decarboxylase is regulated by NQO1. Molecular Cell. 17: 645-55. PMID 15749015 DOI: 10.1016/J.Molcel.2005.01.020  0.617
2005 Asher G, Tsvetkov P, Kahana C, Shaul Y. A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73. Genes & Development. 19: 316-21. PMID 15687255 DOI: 10.1101/Gad.319905  0.598
2005 Cooper A, Shaul Y. Recombinant viral capsids as an efficient vehicle of oligonucleotide delivery into cells. Biochemical and Biophysical Research Communications. 327: 1094-9. PMID 15652509 DOI: 10.1016/J.Bbrc.2004.12.118  0.354
2004 Shlomai A, Shaul Y. RNA interference--small RNAs effectively fight viral hepatitis. Liver International : Official Journal of the International Association For the Study of the Liver. 24: 526-31. PMID 15566500 DOI: 10.1111/J.1478-3231.2004.0960.X  0.656
2004 Murai K, Naruse Y, Shaul Y, Agata Y, Mori N. Direct interaction of NRSF with TBP: chromatin reorganization and core promoter repression for neuron-specific gene transcription. Nucleic Acids Research. 32: 3180-9. PMID 15197246 DOI: 10.1093/Nar/Gkh550  0.366
2004 Asher G, Lotem J, Sachs L, Shaul Y. p53-dependent apoptosis and NAD(P)H:quinone oxidoreductase 1. Methods in Enzymology. 382: 278-93. PMID 15047108 DOI: 10.1016/S0076-6879(04)82016-0  0.34
2004 Doitsh G, Shaul Y. Enhancer I predominance in hepatitis B virus gene expression. Molecular and Cellular Biology. 24: 1799-808. PMID 14749394 DOI: 10.1128/Mcb.24.4.1799-1808.2004  0.463
2003 Asher G, Lotem J, Tsvetkov P, Reiss V, Sachs L, Shaul Y. P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1. Proceedings of the National Academy of Sciences of the United States of America. 100: 15065-70. PMID 14634213 DOI: 10.1073/Pnas.2436329100  0.589
2003 Cooper A, Paran N, Shaul Y. The earliest steps in hepatitis B virus infection. Biochimica Et Biophysica Acta. 1614: 89-96. PMID 12873769 DOI: 10.1016/S0005-2736(03)00166-4  0.389
2003 Ben-Yehoyada M, Ben-Dor I, Shaul Y. c-Abl tyrosine kinase selectively regulates p73 nuclear matrix association. The Journal of Biological Chemistry. 278: 34475-82. PMID 12824179 DOI: 10.1074/Jbc.M301051200  0.339
2003 Doitsh G, Shaul Y. A long HBV transcript encoding pX is inefficiently exported from the nucleus. Virology. 309: 339-49. PMID 12758180 DOI: 10.1016/S0042-6822(03)00156-9  0.42
2003 Paran N, Cooper A, Shaul Y. Interaction of hepatitis B virus with cells. Reviews in Medical Virology. 13: 137-43. PMID 12740829 DOI: 10.1002/Rmv.376  0.39
2003 Shlomai A, Shaul Y. Inhibition of hepatitis B virus expression and replication by RNA interference. Hepatology (Baltimore, Md.). 37: 764-70. PMID 12668968 DOI: 10.1053/Jhep.2003.50146  0.672
2002 Asher G, Lotem J, Sachs L, Kahana C, Shaul Y. Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1. Proceedings of the National Academy of Sciences of the United States of America. 99: 13125-30. PMID 12232053 DOI: 10.1073/Pnas.202480499  0.361
2002 Kapetanopoulos A, Fresser F, Millonig G, Shaul Y, Baier G, Utermann G. Direct interaction of the extracellular matrix protein DANCE with apolipoprotein(a) mediated by the kringle IV-type 2 domain. Molecular Genetics and Genomics : Mgg. 267: 440-6. PMID 12111551 DOI: 10.1007/S00438-002-0673-6  0.308
2002 Zemel R, Koren C, Bachmatove L, Avigad S, Kaganovsky E, Okon E, Ben-Ari Z, Grief F, Ben-Yehoyada M, Shaul Y, Tur-Kaspa R. p73 overexpression and nuclear accumulation in hepatitis C virus-associated hepatocellular carcinoma. Digestive Diseases and Sciences. 47: 716-22. PMID 11991598 DOI: 10.1023/A:1014767311799  0.351
2002 Shamay M, Barak O, Shaul Y. HBXAP, a novel PHD-finger protein, possesses transcription repression activity. Genomics. 79: 523-9. PMID 11944984 DOI: 10.1006/Geno.2002.6717  0.426
2002 Asher G, Lotem J, Kama R, Sachs L, Shaul Y. NQO1 stabilizes p53 through a distinct pathway. Proceedings of the National Academy of Sciences of the United States of America. 99: 3099-104. PMID 11867746 DOI: 10.1073/Pnas.052706799  0.363
2002 Shamay M, Barak O, Doitsh G, Ben-Dor I, Shaul Y. Hepatitis B virus pX interacts with HBXAP, a PHD finger protein to coactivate transcription. The Journal of Biological Chemistry. 277: 9982-8. PMID 11788598 DOI: 10.1074/Jbc.M111354200  0.475
2001 Shamay M, Agami R, Shaul Y. HBV integrants of hepatocellular carcinoma cell lines contain an active enhancer. Oncogene. 20: 6811-9. PMID 11687960 DOI: 10.1038/Sj.Onc.1204879  0.414
2001 Paran N, Geiger B, Shaul Y. HBV infection of cell culture: evidence for multivalent and cooperative attachment. The Embo Journal. 20: 4443-53. PMID 11500372 DOI: 10.1093/Emboj/20.16.4443  0.408
2001 Böcher WO, Dekel B, Schwerin W, Geissler M, Hoffmann S, Rohwer A, Arditti F, Cooper A, Bernhard H, Berrebi A, Rose-John S, Shaul Y, Galle PR, Löhr HF, Reisner Y. Induction of strong hepatitis B virus (HBV) specific T helper cell and cytotoxic T lymphocyte responses by therapeutic vaccination in the trimera mouse model of chronic HBV infection. European Journal of Immunology. 31: 2071-9. PMID 11449360 DOI: 10.1002/1521-4141(200107)31:7<2071::Aid-Immu2071>3.0.Co;2-D  0.332
2001 Katan-Khaykovich Y, Shaul Y. Nuclear import and DNA-binding activity of RFX1. Evidence for an autoinhibitory mechanism. European Journal of Biochemistry / Febs. 268: 3108-16. PMID 11358531 DOI: 10.1046/J.1432-1327.2001.02211.X  0.402
2001 Barak O, Aronheim A, Shaul Y. HBV X protein targets HIV Tat-binding protein 1. Virology. 283: 110-20. PMID 11312667 DOI: 10.1006/Viro.2001.0883  0.416
2001 Strano S, Munarriz E, Rossi M, Castagnoli L, Shaul Y, Sacchi A, Oren M, Sudol M, Cesareni G, Blandino G. Physical interaction with Yes-associated protein enhances p73 transcriptional activity. The Journal of Biological Chemistry. 276: 15164-73. PMID 11278685 DOI: 10.1074/Jbc.M010484200  0.393
2001 Purcell NH, Yu C, He D, Xiang J, Paran N, DiDonato JA, Yamaoka S, Shaul Y, Lin A. Activation of NF-kappaB by hepatitis B virus X protein through an IkappaB kinase-independent mechanism. American Journal of Physiology. Gastrointestinal and Liver Physiology. 280: G669-77. PMID 11254493 DOI: 10.1152/Ajpgi.2001.280.4.G669  0.38
2001 Lee DK, Park SH, Yi Y, Choi SG, Lee C, Parks WT, Cho H, de Caestecker MP, Shaul Y, Roberts AB, Kim SJ. The hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis. Genes & Development. 15: 455-66. PMID 11230153 DOI: 10.1101/Gad.856201  0.358
2001 Asher G, Lotem J, Cohen B, Sachs L, Shaul Y. Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1. Proceedings of the National Academy of Sciences of the United States of America. 98: 1188-93. PMID 11158615 DOI: 10.1073/Pnas.98.3.1188  0.377
2001 Nussbaum O, Paran N, Daudi N, Berr S, Klain A, Eid A, Jurim O, Shaul Y, Dagan S, Galun E. Hepatitis B virus covalently closed circular DNA in sera of infected patients Journal of Hepatology. 34: 109-110. DOI: 10.1016/S0168-8278(01)81268-X  0.355
2000 Strano S, Munarriz E, Rossi M, Cristofanelli B, Shaul Y, Castagnoli L, Levine AJ, Sacchi A, Cesareni G, Oren M, Blandino G. Physical and functional interaction between p53 mutants and different isoforms of p73. The Journal of Biological Chemistry. 275: 29503-12. PMID 10884390 DOI: 10.1074/Jbc.M003360200  0.333
2000 Shaul Y. c-Abl: activation and nuclear targets. Cell Death and Differentiation. 7: 10-6. PMID 10713716 DOI: 10.1038/Sj.Cdd.4400626  0.382
2000 Paran N, Ori A, Haviv I, Shaul Y. A composite polyadenylation signal with TATA box function. Molecular and Cellular Biology. 20: 834-41. PMID 10629040 DOI: 10.1128/Mcb.20.3.834-841.2000  0.446
1999 Doitsh G, Shaul Y. HBV transcription repression in response to genotoxic stress is p53-dependent and abrogated by pX. Oncogene. 18: 7506-13. PMID 10602509 DOI: 10.1038/Sj.Onc.1203209  0.455
1999 Katan-Khaykovich Y, Spiegel I, Shaul Y. The dimerization/repression domain of RFX1 is related to a conserved region of its yeast homologues Crt1 and Sak1: A new function for an ancient motif Journal of Molecular Biology. 294: 121-137. PMID 10556033 DOI: 10.1006/Jmbi.1999.3245  0.396
1999 Agami R, Blandino G, Oren M, Shaul Y. Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis. Nature. 399: 809-13. PMID 10391250 DOI: 10.1038/21697  0.348
1998 Katan-Khaykovich Y, Shaul Y. RFX1, a single DNA-binding protein with a split dimerization domain, generates alternative complexes. The Journal of Biological Chemistry. 273: 24504-12. PMID 9733744 DOI: 10.1074/Jbc.273.38.24504  0.391
1998 Berger I, Shaul Y. c-Fos antagonizes the junD gene positive autoregulatory loop; a novel c-Fos role in promoter switching. Gene. 211: 375-82. PMID 9602173 DOI: 10.1016/S0378-1119(98)00120-6  0.377
1998 Agami R, Shaul Y. The kinase activity of c-Abl but not v-Abl is potentiated by direct interaction with RFXI, a protein that binds the enhancers of several viruses and cell-cycle regulated genes. Oncogene. 16: 1779-88. PMID 9583676 DOI: 10.1038/Sj.Onc.1201708  0.394
1998 Haviv I, Matza Y, Shaul Y. pX, the HBV-encoded coactivator, suppresses the phenotypes of TBP and TAFII250 mutants. Genes & Development. 12: 1217-26. PMID 9553050 DOI: 10.1101/Gad.12.8.1217  0.449
1998 Haviv I, Shamay M, Doitsh G, Shaul Y. Hepatitis B virus pX targets TFIIB in transcription coactivation. Molecular and Cellular Biology. 18: 1562-9. PMID 9488473 DOI: 10.1128/Mcb.18.3.1562  0.451
1998 Ori A, Zauberman A, Doitsh G, Paran N, Oren M, Shaul Y. p53 binds and represses the HBV enhancer: an adjacent enhancer element can reverse the transcription effect of p53. The Embo Journal. 17: 544-53. PMID 9430645 DOI: 10.1093/Emboj/17.2.544  0.462
1997 Katan Y, Agami R, Shaul Y. The transcriptional activation and repression domains of RFX1, a context-dependent regulator, can mutually neutralize their activities. Nucleic Acids Research. 25: 3621-8. PMID 9278482 DOI: 10.1093/Nar/25.18.3621  0.402
1996 Haviv I, Vaizel D, Shaul Y. pX, the HBV-encoded coactivator, interacts with components of the transcription machinery and stimulates transcription in a TAF-independent manner. The Embo Journal. 15: 3413-20. PMID 8670843 DOI: 10.1002/J.1460-2075.1996.Tb00707.X  0.422
1996 Dikstein R, Agami R, Heffetz D, Shaul Y. p140/c-Abl that binds DNA is preferentially phosphorylated at tyrosine residues. Proceedings of the National Academy of Sciences of the United States of America. 93: 2387-91. PMID 8637883 DOI: 10.1073/Pnas.93.6.2387  0.69
1995 Ori A, Shaul Y. Hepatitis B virus enhancer binds and is activated by the Hepatocyte nuclear factor 3. Virology. 207: 98-106. PMID 7871756 DOI: 10.1006/Viro.1995.1055  0.397
1995 Haviv I, Vaizel D, Shaul Y. The X protein of hepatitis B virus coactivates potent activation domains. Molecular and Cellular Biology. 15: 1079-85. PMID 7823923 DOI: 10.1128/Mcb.15.2.1079  0.36
1994 Berger I, Shaul Y. The human junD gene is positively and selectively autoregulated Dna and Cell Biology. 13: 249-255. PMID 8172655 DOI: 10.1089/Dna.1994.13.249  0.372
1994 De-Medina T, Shaul Y. Functional and structural similarity between the X protein of hepatitis B virus and nucleoside diphosphate kinases. Febs Letters. 351: 423-6. PMID 8082807 DOI: 10.1016/0014-5793(94)00900-7  0.444
1994 De-Medina T, Haviv I, Noiman S, Shaul Y. The X protein of hepatitis B virus has a ribo/deoxy ATPase activity Virology. 202: 401-407. PMID 8009850 DOI: 10.1006/Viro.1994.1356  0.476
1994 Ori A, Atzmony D, Haviv I, Shaul Y. An NF1 motif plays a central role in hepatitis B virus enhancer. Virology. 204: 600-8. PMID 7941327 DOI: 10.1006/Viro.1994.1574  0.45
1992 Dikstein R, Heffetz D, Ben-Neriah Y, Shaul Y. c-abl has a sequence-specific enhancer binding activity. Cell. 69: 751-7. PMID 1591775 DOI: 10.1016/0092-8674(92)90287-M  0.685
1990 Dikstein R, Faktor O, Shaul Y. Hierarchic and cooperative binding of the rat liver nuclear protein C/EBP at the hepatitis B virus enhancer Molecular and Cellular Biology. 10: 4427-4430. PMID 2370872 DOI: 10.1128/Mcb.10.8.4427  0.702
1990 Dikstein R, Faktor O, Ben-Levy R, Shaul Y. Functional organization of the hepatitis B virus enhancer Molecular and Cellular Biology. 10: 3683-3689. PMID 2355919 DOI: 10.1128/Mcb.10.7.3683  0.678
1990 Unger T, Shaul Y. The X protein of the hepatitis B virus acts as a transcription factor when targeted to its responsive element Embo Journal. 9: 1889-1895. PMID 2347309 DOI: 10.1002/J.1460-2075.1990.Tb08315.X  0.437
1990 Faktor O, Budlovsky S, Ben-Levy R, Shaul Y. A single element within the hepatitis B virus enhancer binds multiple proteins and responds to multiple stimuli Journal of Virology. 64: 1861-1863. PMID 2319654 DOI: 10.1128/Jvi.64.4.1861-1863.1990  0.384
1989 Honigwachs J, Faktor O, Dikstein R, Shaul Y, Laub O. Liver-specific expression of hepatitis B virus is determined by the combined action of the core gene promoter and the enhancer Journal of Virology. 63: 919-924. PMID 2911125 DOI: 10.1128/Jvi.63.2.919-924.1989  0.711
1989 Ben-Levy R, Faktor O, Berger I, Shaul Y. Cellular factors that interact with the hepatitis B virus enhancer Molecular and Cellular Biology. 9: 1804-1809. PMID 2725524 DOI: 10.1128/Mcb.9.4.1804  0.421
1988 Faktor O, De-Medina T, Shaul Y. Regulation of hepatitis B virus S gene promoter in transfected cell lines Virology. 162: 362-368. PMID 3422523 DOI: 10.1016/0042-6822(88)90476-X  0.431
1988 Tur-Kaspa R, Shaul Y, Moore DD, Burk RD, Okret S, Poellinger L, Shafritz DA. The glucocorticoid receptor recognizes a specific nucleotide sequence in hepatitis B virus DNA causing increased activity of the HBV enhancer. Virology. 167: 630-3. PMID 3201757 DOI: 10.1016/0042-6822(88)90127-4  0.404
1988 De-Medina T, Faktor O, Shaul Y. The S promoter of hepatitis B virus is regulated by positive and negative elements Molecular and Cellular Biology. 8: 2449-2455. PMID 3165491 DOI: 10.1128/Mcb.8.6.2449  0.405
1987 Shaul Y, Ben-Levy R. Multiple nuclear proteins in liver cells are bound to hepatitis B virus enhancer element and its upstream sequences Embo Journal. 6: 1913-1920. PMID 3653073 DOI: 10.1002/J.1460-2075.1987.Tb02451.X  0.433
1987 Berger I, Shaul Y. Integration of hepatitis B virus: Analysis of unoccupied sites Journal of Virology. 61: 1180-1186. PMID 3029413 DOI: 10.1128/Jvi.61.4.1180-1186.1987  0.342
1986 Shaul Y, Ben-Levy R, De-Medina T. High affinity binding site for nuclear factor I next to the hepatitis B virus S gene promoter The Embo Journal. 5: 1967-1971. PMID 3463507 DOI: 10.1002/J.1460-2075.1986.Tb04451.X  0.45
1986 Shaul Y, Garcia PD, Schonberg S, Rutter WJ. Integration of hepatitis B virus DNA in chromosome-specific satellite sequences Journal of Virology. 59: 731-734. PMID 3016335 DOI: 10.1128/Jvi.59.3.731-734.1986  0.322
1986 Tur-Kaspa R, Burk RD, Shaul Y, Shafritz DA. Hepatitis B virus DNA contains a glucocorticoid-responsive element Proceedings of the National Academy of Sciences of the United States of America. 83: 1627-1631. PMID 3006059 DOI: 10.1073/Pnas.83.6.1627  0.413
1985 Shaul Y, Rutter WJ, Laub O. A human hepatitis B viral enhancer element Embo Journal. 4: 427-430. PMID 3926485 DOI: 10.1002/J.1460-2075.1985.Tb03646.X  0.408
1985 Shaul Y, Laub O, Walker MD, Rutter WJ. Homologous recombination between a defective virus and a chromosomal sequence in mammalian cells Proceedings of the National Academy of Sciences of the United States of America. 82: 3781-3784. PMID 2987945 DOI: 10.1073/Pnas.82.11.3781  0.338
1985 Ziemer M, Garcia P, Shaul Y, Rutter WJ. Sequence of hepatitis B virus DNA incorporated into the genome of the human hepatoma cell line Journal of Virology. 53: 885-892. PMID 2983098 DOI: 10.1128/Jvi.53.3.885-892.1985  0.355
1983 Laub O, Rall LB, Truett M, Shaul Y, Standring DN, Valenzuela P, Rutter WJ. Synthesis of hepatitis B surface antigen in mammalian cells: Expression of the entire gene and the coding region Journal of Virology. 48: 271-280. PMID 6310147 DOI: 10.1128/Jvi.48.1.271-280.1983  0.365
1982 Shaul Y, Ginzburg I, Aviv H. Preferential transcription and nuclear transport of globin gene sequences, as control steps leading to final differentiation of murine erythroleukemic cells. European Journal of Biochemistry. 128: 637-42. PMID 6897535 DOI: 10.1111/J.1432-1033.1982.Tb07011.X  0.365
1981 Keshet E, Shaul Y. Terminal direct repeats in a retrovirus-like repeated mouse gene family. Nature. 289: 83-5. PMID 6256651 DOI: 10.1038/289083A0  0.349
1981 Shaul Y, Ginzburg I, Aviv H. Modulation of globin gene expression by a tumor promoter during induced differentiation of Friend erythroleukemic cells. European Journal of Biochemistry. 114: 591-5. PMID 6113141 DOI: 10.1111/J.1432-1033.1981.Tb05185.X  0.326
1980 Keshet E, Shaul Y, Kaminchik J, Aviv H. Heterogeneity of "virus-like" genes encoding retrovirus-associated 30S RNA and their organization within the mouse genome. Cell. 20: 431-9. PMID 6248245 DOI: 10.1016/0092-8674(80)90629-7  0.355
Low-probability matches (unlikely to be authored by this person)
2006 Cooper A, Shaul Y. Clathrin-mediated endocytosis and lysosomal cleavage of hepatitis B virus capsid-like core particles. The Journal of Biological Chemistry. 281: 16563-9. PMID 16618702 DOI: 10.1074/Jbc.M601418200  0.298
2013 Reuven N, Shaul Y. The c-Abl/YAP/p73 apoptotic module and the HIPPO pathway The Hippo Signaling Pathway and Cancer. 2147483647: 173-195. DOI: 10.1007/978-1-4614-6220-0_9  0.294
1990 Faktor O, Shaul Y. The identification of hepatitis B virus X gene responsive elements reveals functional similarity of X and HTLV-I tax Oncogene. 5: 867-872. PMID 2359621  0.293
2005 Shaul Y, Ben-Yehoyada M. Role of c-Abl in the DNA damage stress response. Cell Research. 15: 33-5. PMID 15686624 DOI: 10.1038/Sj.Cr.7290261  0.293
2009 Blandino G, Shaul Y, Strano S, Sudol M, Yaffe M. The hippo tumor suppressor pathway: A brainstorming workshop Science Signaling. 2: mr6. PMID 19887678 DOI: 10.1126/Scisignal.295Mr6  0.289
1980 Nudel U, Katcoff D, Carmon Y, Zevin-Sonkin D, Levi Z, Shaul Y, Shani M, Yaffe D. Identification of recombinant phages containing sequences from different rat myosin heavy chain genes Nucleic Acids Research. 8: 2133-2146. PMID 7433088 DOI: 10.1093/Nar/8.10.2133  0.283
2004 Kiel C, Selzer T, Shaul Y, Schreiber G, Herrmann C. Electrostatically optimized Ras-binding Ral guanine dissociation stimulator mutants increase the rate of association by stabilizing the encounter complex. Proceedings of the National Academy of Sciences of the United States of America. 101: 9223-8. PMID 15197281 DOI: 10.1073/Pnas.0401160101  0.282
1995 Shaul Y, Haviv I, Veizel D. The X protein of HBV acts as a transcription coactivator both in vivo and in vitro Journal of Cancer Research and Clinical Oncology. 121: S15-S15. DOI: 10.1007/BF02559814  0.277
2010 Shaul Y, Reuven N. The role of p53 in nutrients levels. Cell Cycle (Georgetown, Tex.). 9: 3646-7. PMID 20930502 DOI: 10.4161/Cc.9.18.13222  0.273
1984 Shaul Y, Ziemer M, Garcia PD, Crawford R, Hsu H, Valenzuela P, Rutter WJ. Cloning and analysis of integrated hepatitis virus sequences from a human hepatoma cell line Journal of Virology. 51: 776-787. PMID 6088800 DOI: 10.1128/Jvi.51.3.776-787.1984  0.273
1995 Noiman S, Shaul Y. Detection of histidine-phospho-proteins in animal tissues. Febs Letters. 364: 63-6. PMID 7750545 DOI: 10.1016/0014-5793(95)00358-G  0.272
2006 Preis M, Cohen T, Sarnatzki Y, Ben Yosef Y, Schneiderman J, Gluzman Z, Koren B, Lewis BS, Shaul Y, Flugelman MY. Effects of fibulin-5 on attachment, adhesion, and proliferation of primary human endothelial cells. Biochemical and Biophysical Research Communications. 348: 1024-33. PMID 16904068 DOI: 10.1016/J.Bbrc.2006.07.156  0.271
2000 Zemel R, Koren C, Bachmatove L, Ben-Ari Z, Grief F, Ben-Yehoyada M, Shaul Y, Tur Kaspa R. Differential expression of p73 in HCV associated hepatocellular carcinoma Journal of Hepatology. 32: 86. DOI: 10.1016/S0168-8278(00)80661-3  0.27
2022 Biran A, Myers N, Steinberger S, Adler J, Riutin M, Broennimann K, Reuven N, Shaul Y. The C-Terminus of the PSMA3 Proteasome Subunit Preferentially Traps Intrinsically Disordered Proteins for Degradation. Cells. 11. PMID 36291102 DOI: 10.3390/cells11203231  0.267
2006 Asher G, Shaul Y. Ubiquitin-independent degradation: lessons from the p53 model. The Israel Medical Association Journal : Imaj. 8: 229-32. PMID 16671355  0.265
1981 Shaul Y, Kaminchik J, Aviv H. Large globin RNA molecules and their processing. European Journal of Biochemistry. 116: 461-6. PMID 6167440 DOI: 10.1111/J.1432-1033.1981.Tb05358.X  0.264
2015 Keshet R, Reuven N, Shaul Y. c-Abl forces YAP to switch sides. Molecular & Cellular Oncology. 2: e995006. PMID 27308475 DOI: 10.4161/23723556.2014.995006  0.261
2022 Broennimann K, Ricardo-Lax I, Adler J, Shaul Y. Evidence for a Hepatitis B Virus Short RNA Fragment Directly Targeting the Cellular RRM2 Gene. Cells. 11. PMID 35883690 DOI: 10.3390/cells11142248  0.257
2023 Steinberger S, Adler J, Shaul Y. Method of Monitoring 26S Proteasome in Cells Revealed the Crucial Role of PSMA3 C-Terminus in 26S Integrity. Biomolecules. 13. PMID 37371572 DOI: 10.3390/biom13060992  0.249
2023 Strobelt R, Adler J, Shaul Y. The Transmembrane Protease Serine 2 (TMPRSS2) Non-Protease Domains Regulating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike-Mediated Virus Entry. Viruses. 15. PMID 37896901 DOI: 10.3390/v15102124  0.246
2006 Shaul YD, Seger R. ERK1c regulates Golgi fragmentation during mitosis. The Journal of Cell Biology. 172: 885-97. PMID 16533948 DOI: 10.1083/Jcb.200509063  0.232
1995 Shaulian E, Haviv I, Shaul Y, Oren M. Transcriptional repression by the C-terminal domain of p53 Oncogene. 10: 671-680. PMID 7862444  0.232
2005 Vanlandschoot P, Leroux-Roels G, Cooper A, Tal G, Shaul Y. The role of heparan sulfate and TLR2 in cytokine induction by hepatitis B virus capsids (multiple letters) Journal of Immunology. 175: 6253-6255. PMID 16272274  0.228
2019 Reuven N, Adler J, Broennimann K, Myers N, Shaul Y. Recruitment of DNA Repair MRN Complex by Intrinsically Disordered Protein Domain Fused to Cas9 Improves Efficiency of CRISPR-Mediated Genome Editing. Biomolecules. 9. PMID 31597252 DOI: 10.3390/biom9100584  0.228
2011 McNeill H, Sudol M, Halder G, Strano S, Blandino G, Shaul Y. The Hippo tumor suppressor pathway: a report on 'the Second Workshop On The Hippo tumor suppressor pathway'. Cell Death and Differentiation. 18: 1388-90. PMID 21566666 DOI: 10.1038/Cdd.2011.61  0.218
2020 Benitez EK, Lomova Kaufman A, Cervantes L, Clark DN, Ayoub PG, Senadheera S, Osborne K, Sanchez JM, Crisostomo RV, Wang X, Reuven N, Shaul Y, Hollis RP, Romero Z, Kohn DB. Global and Local Manipulation of DNA Repair Mechanisms to Alter Site-Specific Gene Editing Outcomes in Hematopoietic Stem Cells. Frontiers in Genome Editing. 2: 601541. PMID 34713224 DOI: 10.3389/fgeed.2020.601541  0.208
1991 Berger I, Shaul Y. Structure and function of human jun-D Oncogene. 6: 561-566. PMID 1903194  0.205
2015 Preis M, Schneiderman J, Koren B, Ben-Yosef Y, Levin-Ashkenazi D, Shapiro S, Cohen T, Blich M, Israeli-Amit M, Sarnatzki Y, Gershtein D, Shofti R, Lewis BS, Shaul Y, Flugelman MY. Co-expression of fibulin-5 and VEGF165 increases long-term patency of synthetic vascular grafts seeded with autologous endothelial cells. Gene Therapy. PMID 26588709 DOI: 10.1038/Gt.2015.104  0.204
2011 Lindquist RA, Ottina KA, Wheeler DB, Hsu PP, Thoreen CC, Guertin DA, Ali SM, Sengupta S, Shaul YD, Lamprecht MR, Madden KL, Papallo AR, Jones TR, Sabatini DM, Carpenter AE. Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1-S6K pathway signaling. Genome Research. 21: 433-46. PMID 21239477 DOI: 10.1101/Gr.111492.110  0.204
2000 Litvak V, Tian D, Shaul YD, Lev S. Targeting of PYK2 to focal adhesions as a cellular mechanism for convergence between integrins and G protein-coupled receptor signaling cascades. The Journal of Biological Chemistry. 275: 32736-46. PMID 10915788 DOI: 10.1074/Jbc.M004200200  0.202
2004 Aebersold DM, Shaul YD, Yung Y, Yarom N, Yao Z, Hanoch T, Seger R. Extracellular signal-regulated kinase 1c (ERK1c), a novel 42-kilodalton ERK, demonstrates unique modes of regulation, localization, and function. Molecular and Cellular Biology. 24: 10000-15. PMID 15509801 DOI: 10.1128/Mcb.24.22.10000-10015.2004  0.2
2001 Garti N, Aserin A, Wachtel E, Gans O, Shaul Y. Water Solubilization in Nonionic Microemulsions Stabilized by Grafted Siliconic Emulsifiers. Journal of Colloid and Interface Science. 233: 286-294. PMID 11121278 DOI: 10.1006/Jcis.2000.7226  0.199
2009 Shaul YD, Gibor G, Plotnikov A, Seger R. Specific phosphorylation and activation of ERK1c by MEK1b: a unique route in the ERK cascade. Genes & Development. 23: 1779-90. PMID 19651986 DOI: 10.1101/Gad.523909  0.189
2015 Reuven N, Adler J, Porat Z, Polonio-Vallon T, Hofmann TG, Shaul Y. The tyrosine kinase c-Abl promotes homeodomaininteracting protein kinase 2 (HIPK2) accumulation and activation in response to DNA damage Journal of Biological Chemistry. 290: 16478-16488. DOI: 10.1074/jbc.M114.628982  0.185
2005 Shaul Y, Schreiber G. Exploring the charge space of protein-protein association: a proteomic study. Proteins. 60: 341-52. PMID 15887221 DOI: 10.1002/prot.20489  0.182
2015 Shaul YD, Yuan B, Thiru P, Nutter-Upham A, McCallum S, Lanzkron C, Bell GW, Sabatini DM. MERAV: a tool for comparing gene expression across human tissues and cell types. Nucleic Acids Research. PMID 26626150 DOI: 10.1093/nar/gkv1337  0.182
2014 Shaul YD, Freinkman E, Comb WC, Cantor JR, Tam WL, Thiru P, Kim D, Kanarek N, Pacold ME, Chen WW, Bierie B, Possemato R, Reinhardt F, Weinberg RA, Yaffe MB, et al. Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition. Cell. 158: 1094-109. PMID 25171410 DOI: 10.1016/J.Cell.2014.07.032  0.182
2006 Schreiber G, Shaul Y, Gottschalk KE. Electrostatic design of protein-protein association rates. Methods in Molecular Biology (Clifton, N.J.). 340: 235-49. PMID 16957340 DOI: 10.1385/1-59745-116-9:235  0.176
2021 Reuven N, Adler J, Myers N, Shaul Y. CRISPR Co-Editing Strategy for Scarless Homology-Directed Genome Editing. International Journal of Molecular Sciences. 22. PMID 33916763 DOI: 10.3390/ijms22073741  0.167
2022 Strobelt R, Adler J, Paran N, Yahalom-Ronen Y, Melamed S, Politi B, Shulman Z, Schmiedel D, Shaul Y. Imatinib inhibits SARS-CoV-2 infection by an off-target-mechanism. Scientific Reports. 12: 5758. PMID 35388061 DOI: 10.1038/s41598-022-09664-1  0.166
2008 Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science (New York, N.Y.). 320: 1496-501. PMID 18497260 DOI: 10.1126/science.1157535  0.165
2011 Possemato R, Marks KM, Shaul YD, Pacold ME, Kim D, Birsoy K, Sethumadhavan S, Woo HK, Jang HG, Jha AK, Chen WW, Barrett FG, Stransky N, Tsun ZY, Cowley GS, et al. Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. Nature. 476: 346-50. PMID 21760589 DOI: 10.1038/Nature10350  0.16
2007 Shaul YD, Seger R. The MEK/ERK cascade: from signaling specificity to diverse functions. Biochimica Et Biophysica Acta. 1773: 1213-26. PMID 17112607 DOI: 10.1016/J.Bbamcr.2006.10.005  0.157
2022 Reuven N, Shaul Y. Selecting for CRISPR-Edited Knock-In Cells. International Journal of Molecular Sciences. 23. PMID 36233222 DOI: 10.3390/ijms231911919  0.157
2023 Adler J, Oren R, Shaul Y. Depleting the 19S proteasome regulatory PSMD1 subunit as a cancer therapy strategy. Cancer Medicine. PMID 36934426 DOI: 10.1002/cam4.5775  0.145
2002 Litvak V, Shaul YD, Shulewitz M, Amarilio R, Carmon S, Lev S. Targeting of Nir2 to lipid droplets is regulated by a specific threonine residue within its PI-transfer domain. Current Biology : Cb. 12: 1513-8. PMID 12225667 DOI: 10.1016/S0960-9822(02)01107-7  0.143
2015 Patterson HC, Gerbeth C, Thiru P, Vögtle NF, Knoll M, Shahsafaei A, Samocha KE, Huang CX, Harden MM, Song R, Chen C, Kao J, Shi J, Salmon W, Shaul YD, et al. A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 26438848 DOI: 10.1073/Pnas.1517932112  0.14
2005 Shaul Y, Seger R. The detection of MAPK signaling. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 14.3. PMID 18228462 DOI: 10.1002/0471143030.Cb1403S28  0.14
2006 Shaul Y, Seger R. The detection of MAPK signaling. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 18.12. PMID 18265377 DOI: 10.1002/0471142727.Mb1812S73  0.139
2023 Strobelt R, Broennimann K, Adler J, Shaul Y. SARS-CoV-2 Omicron Specific Mutations Affecting Infectivity, Fusogenicity, and Partial TMPRSS2-Independency. Viruses. 15. PMID 37243215 DOI: 10.3390/v15051129  0.126
2014 Kanarek N, Grivennikov SI, Leshets M, Lasry A, Alkalay I, Horwitz E, Shaul YD, Stachler M, Voronov E, Apte RN, Pagano M, Pikarsky E, Karin M, Ghosh S, Ben-Neriah Y. Critical role for IL-1β in DNA damage-induced mucositis. Proceedings of the National Academy of Sciences of the United States of America. 111: E702-11. PMID 24469832 DOI: 10.1073/Pnas.1322691111  0.125
2014 Keshet R, Kraitshtein ZB, Shanzer M, Adler J, Reuven N, Shaul Y. C-Abl tyrosine kinase promotes adipocyte differentiation by targeting PPAR-gamma 2 Proceedings of the National Academy of Sciences of the United States of America. 111: 16365-16370. DOI: 10.1073/pnas.1411086111  0.123
2023 Tsitsou-Kampeli A, Suzzi S, Kenigsbuch M, Satomi A, Strobelt R, Singer O, Feldmesser E, Purnapatre M, Colaiuta SP, David E, Cahalon L, Hahn O, Wyss-Coray T, Shaul Y, Amit I, et al. Cholesterol 24-hydroxylase at the choroid plexus contributes to brain immune homeostasis. Cell Reports. Medicine. 101278. PMID 37944529 DOI: 10.1016/j.xcrm.2023.101278  0.115
1999 Cohen E, Ophir I, Shaul YB. Induced differentiation in HT29, a human colon adenocarcinoma cell line. Journal of Cell Science. 112: 2657-66. PMID 10413674  0.112
1985 Zimber A, Shaul Y, Hod I. Inhibition of DNA synthesis in Ehrlich ascites tumor cells in vitro and of tumor growth in vivo by valinomycin Federation Proceedings. 44.  0.112
2016 Pacold ME, Brimacombe KR, Chan SH, Rohde JM, Lewis CA, Swier LJ, Possemato R, Chen WW, Sullivan LB, Fiske BP, Cho S, Freinkman E, Birsoy K, Abu-Remaileh M, Shaul YD, et al. A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate. Nature Chemical Biology. PMID 27110680 DOI: 10.1038/Nchembio.2070  0.11
2014 Wilensky A, Segev H, Mizraji G, Shaul Y, Capucha T, Shacham M, Hovav AH. Dendritic cells and their role in periodontal disease. Oral Diseases. 20: 119-26. PMID 23656605 DOI: 10.1111/odi.12122  0.103
2014 Keshet R, Adler J, Ricardo Lax I, Shanzer M, Porat Z, Reuven N, Shaul Y. c-Abl antagonizes the YAP oncogenic function Cell Death and Differentiation. DOI: 10.1038/cdd.2014.182  0.097
2014 Elnekave M, Furmanov K, Shaul Y, Capucha T, Eli-Berchoer L, Zelentsova K, Clausen BE, Hovav AH. Second-generation Langerhans cells originating from epidermal precursors are essential for CD8+ T cell priming. Journal of Immunology (Baltimore, Md. : 1950). 192: 1395-403. PMID 24420922 DOI: 10.4049/jimmunol.1301143  0.093
2010 Porath D, Shaul YB. Growth, greening, and phytochrome in etiolated spirodela (lemnaceae). Plant Physiology. 51: 474-7. PMID 16658354 DOI: 10.1104/pp.51.3.474  0.05
2004 Shaul YD, Seger R. Use of inhibitors in the study of MAPK signaling. Methods in Molecular Biology (Clifton, N.J.). 250: 113-26. PMID 14755084 DOI: 10.1385/1-59259-671-1:113  0.047
1977 Hod I, Zimber A, Gidoni D, Shaul Y. Differences in production of solid Landhscütz tumours in BALB/c and ICR mice. Laboratory Animals. 11: 51-2. PMID 839724 DOI: 10.1258/002367777780959193  0.046
2016 Pacold ME, Brimacombe KR, Chan SH, Rohde JM, Lewis CA, Swier LJ, Possemato R, Chen WW, Sullivan LB, Fiske BP, Cho S, Freinkman E, Birsoy K, Abu MR, Shaul YD, et al. Corrigendum: A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate. Nature Chemical Biology. 12: 656. PMID 27434767 DOI: 10.1038/Nchembio0816-656  0.034
2013 Schwartz M, Shaul Y. Narrative development among language-minority children: The role of bilingual versus monolingual preschool education Language, Culture and Curriculum. 26: 36-51. DOI: 10.1080/07908318.2012.760568  0.022
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