Mariela Segura, Ph.D. - Publications

Affiliations: 
2002 Université de Montréal, Montréal, Canada 
Area:
Microbiology Biology, Immunology, Cell Biology

126 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bleuzé M, Lehoux M, Auger JP, Gottschalk M, Segura M. The granulocyte colony-stimulating factor produced during infection controls neutrophil recruitment in the blood without affecting bacterial clearance. Frontiers in Immunology. 15: 1403789. PMID 39156897 DOI: 10.3389/fimmu.2024.1403789  0.513
2024 Jeffery A, Gilbert M, Corsaut L, Gaudreau A, Obradovic MR, Cloutier S, Frenette MC, Surprenant C, Lacouture S, Arnal JL, Gottschalk M, Segura M. Immune response induced by a Streptococcus suis multi-serotype autogenous vaccine used in sows to protect post-weaned piglets. Veterinary Research. 55: 57. PMID 38715138 DOI: 10.1186/s13567-024-01313-x  0.433
2024 Payen S, Giroux MC, Gisch N, Schombel U, Fittipaldi N, Segura M, Gottschalk M. Lipoteichoic acids influence cell shape and bacterial division of Streptococcus suis serotype 2, but play a limited role in the pathogenesis of the infection. Veterinary Research. 55: 34. PMID 38504299 DOI: 10.1186/s13567-024-01287-w  0.589
2024 Bleuzé M, Lavoie JP, Bédard C, Gottschalk M, Segura M. Encapsulated Streptococcus suis impairs optimal neutrophil functions which are not rescued by priming with colony-stimulating factors. Plos One. 19: e0296844. PMID 38261585 DOI: 10.1371/journal.pone.0296844  0.549
2024 Dolbec D, Lehoux M, de Beauville AA, Zahn A, Di Noia JM, Segura M. Unmutated but T cell dependent IgM antibodies targeting Streptococcus suis play an essential role in bacterial clearance. Plos Pathogens. 20: e1011957. PMID 38241393 DOI: 10.1371/journal.ppat.1011957  0.326
2023 Kerdsin A, Hatrongjit R, Wongsurawat T, Jenjaroenpun P, Zheng H, Chopjitt P, Boueroy P, Fittipaldi N, Segura M, Gottschalk M. Comparative genome analysis of Streptococcus suis serotype 5 strains from humans and pigs revealed pathogenic potential of virulent, antimicrobial resistance, and genetic relationship. Microbes and Infection. 105273. PMID 38070594 DOI: 10.1016/j.micinf.2023.105273  0.506
2023 Fabà L, Aragon V, Litjens R, Galofré-Milà N, Segura M, Gottschalk M, Doelman J. Metabolic insights and background from naturally affected pigs during outbreaks. Translational Animal Science. 7: txad126. PMID 38023423 DOI: 10.1093/tas/txad126  0.448
2023 Payen S, Roy D, Okura M, Segura M, Gottschalk M. Study of the Role of Lipoprotein Maturation Enzymes in the Pathogenesis of the Infection Caused by the Serotype 2 Sequence Type 25 North American Prototype Strain. Pathogens (Basel, Switzerland). 12. PMID 38003790 DOI: 10.3390/pathogens12111325  0.523
2023 Heidarpanah S, Thibodeau A, Parreira VR, Quessy S, Segura M, Gottschalk M, Gaudreau A, Juette T, Gaucher ML. Evaluation of the Immunoprotective Capacity of Five Vaccine Candidate Proteins against Avian Necrotic Enteritis and Impact on the Caecal Microbiota of Vaccinated Birds. Animals : An Open Access Journal From Mdpi. 13. PMID 37958078 DOI: 10.3390/ani13213323  0.484
2023 Dolbec D, Lehoux M, Okura M, Takamatsu D, Gottschalk M, Segura M. surface-antigen recognition by antibodies and bacterial elimination is influenced by capsular polysaccharide structure. Frontiers in Cellular and Infection Microbiology. 13: 1228496. PMID 37545852 DOI: 10.3389/fcimb.2023.1228496  0.483
2023 Pageaut H, Lacouture S, Lehoux M, Marois-Créhan C, Segura M, Gottschalk M. Interactions of and/or with Serotype 2 Using In Vitro Co-Infection Models with Swine Cells. Pathogens (Basel, Switzerland). 12. PMID 37513713 DOI: 10.3390/pathogens12070866  0.567
2023 Hatrongjit R, Boueroy P, Jenjaroenpun P, Wongsurawat T, Meekhanon N, Chopjitt P, Zheng H, Fittipaldi N, Chareonsudjai S, Segura M, Gottschalk M, Kerdsin A. Genomic characterization and virulence of Streptococcus suis serotype 4 clonal complex 94 recovered from human and swine samples. Plos One. 18: e0288840. PMID 37498866 DOI: 10.1371/journal.pone.0288840  0.517
2023 Heidarpanah S, Thibodeau A, Parreira VR, Quessy S, Segura M, Meniaï I, Gottschalk M, Gaudreau A, Juette T, Gaucher ML. Immunization of broiler chickens with five newly identified surface-exposed proteins unique to Clostridium perfringens causing necrotic enteritis. Scientific Reports. 13: 5254. PMID 37002317 DOI: 10.1038/s41598-023-32541-4  0.464
2023 Payen S, Rrodriguez JA, Segura M, Gottschalk M. Laminin-binding protein of Streptococcus suis serotype 2 influences zinc acquisition and cytokine responses. Veterinary Research. 54: 1. PMID 36604750 DOI: 10.1186/s13567-022-01128-8  0.566
2022 Kerdsin A, Segura M, Fittipaldi N, Gottschalk M. Sociocultural Factors Influencing Human Disease in Southeast Asia. Foods (Basel, Switzerland). 11. PMID 35563913 DOI: 10.3390/foods11091190  0.42
2021 Neila-Ibáñez C, Brogaard L, Pailler-García L, Martínez J, Segalés J, Segura M, Heegaard PMH, Aragon V. Piglet innate immune response to Streptococcus suis colonization is modulated by the virulence of the strain. Veterinary Research. 52: 145. PMID 34924012 DOI: 10.1186/s13567-021-01013-w  0.368
2021 Bleuzé M, Gottschalk M, Segura M. Neutrophils in Infection: From Host Defense to Pathology. Microorganisms. 9. PMID 34835517 DOI: 10.3390/microorganisms9112392  0.564
2021 Payen S, Roy D, Boa A, Okura M, Auger JP, Segura M, Gottschalk M. Role of Maturation of Lipoproteins in the Pathogenesis of the Infection Caused by Serotype 2. Microorganisms. 9. PMID 34835511 DOI: 10.3390/microorganisms9112386  0.585
2021 Obradovic MR, Corsaut L, Dolbec D, Gottschalk M, Segura M. Experimental evaluation of protection and immunogenicity of Streptococcus suis bacterin-based vaccines formulated with different commercial adjuvants in weaned piglets. Veterinary Research. 52: 133. PMID 34666827 DOI: 10.1186/s13567-021-01004-x  0.435
2021 Okura M, Auger JP, Shibahara T, Goyette-Desjardins G, Van Calsteren MR, Maruyama F, Kawai M, Osaki M, Segura M, Gottschalk M, Takamatsu D. Capsular polysaccharide switching in Streptococcus suis modulates host cell interactions and virulence. Scientific Reports. 11: 6513. PMID 33753801 DOI: 10.1038/s41598-021-85882-3  0.539
2021 Obradovic MR, Segura M, Segalés J, Gottschalk M. Review of the speculative role of co-infections in Streptococcus suis-associated diseases in pigs. Veterinary Research. 52: 49. PMID 33743838 DOI: 10.1186/s13567-021-00918-w  0.572
2021 Corsaut L, Martelet L, Goyette-Desjardins G, Beauchamp G, Denicourt M, Gottschalk M, Segura M. Immunogenicity study of a Streptococcus suis autogenous vaccine in preparturient sows and evaluation of passive maternal immunity in piglets. Bmc Veterinary Research. 17: 72. PMID 33546699 DOI: 10.1186/s12917-021-02774-4  0.426
2020 Segura M. Research: Progress and Challenges. Pathogens (Basel, Switzerland). 9. PMID 32867188 DOI: 10.3390/Pathogens9090707  0.384
2020 Goyette-Desjardins G, Auger JP, Dolbec D, Vinogradov E, Okura M, Takamatsu D, Van Calsteren MR, Gottschalk M, Segura M. Comparative study of immunogenic properties of purified capsular polysaccharides from serotypes 3, 7, 8, and 9: the serotype 3 polysaccharide induces an opsonizing IgG response. Infection and Immunity. PMID 32747605 DOI: 10.1128/IAI.00377-20  0.537
2020 Bleuzé M, Auger JP, Lavagna A, Gisch N, Gottschalk M, Segura M. In vitro characterization of granulocyte-colony stimulating factor (G-CSF) production by dendritic cells and macrophages during Streptococcus suis infection. Immunobiology. 225: 151979. PMID 32747024 DOI: 10.1016/J.Imbio.2020.151979  0.592
2020 Gauthier L, Babych M, Segura M, Bourgault S, Archambault D. Identification of a novel TLR5 agonist derived from the P97 protein of Mycoplasma hyopneumoniae. Immunobiology. 225: 151962. PMID 32747018 DOI: 10.1016/J.Imbio.2020.151962  0.352
2020 Corsaut L, Misener M, Canning P, Beauchamp G, Gottschalk M, Segura M. Field Study on the Immunological Response and Protective Effect of a Licensed Autogenous Vaccine to Control Infections in Post-Weaned Piglets. Vaccines. 8. PMID 32674276 DOI: 10.3390/Vaccines8030384  0.48
2020 Segura M, Aragon V, Brockmeier SL, Gebhart C, Greeff A, Kerdsin A, O'Dea MA, Okura M, Saléry M, Schultsz C, Valentin-Weigand P, Weinert LA, Wells JM, Gottschalk M. Update on Research and Prevention in the Era of Antimicrobial Restriction: 4th International Workshop on . Pathogens (Basel, Switzerland). 9. PMID 32422856 DOI: 10.3390/Pathogens9050374  0.571
2020 Lavagna A, Auger JP, Giradin SE, Gisch N, Segura M, Gottschalk M. Recognition of Lipoproteins by Toll-like Receptor 2 and DNA by the AIM2 Inflammasome Is Responsible for Production of Interleukin-1β by Virulent Suilysin-negative Serotype 2. Pathogens (Basel, Switzerland). 9. PMID 32098284 DOI: 10.3390/Pathogens9020147  0.549
2019 Auger JP, Rivest S, Benoit-Biancamano MO, Segura M, Gottschalk M. Inflammatory monocytes and neutrophils regulate -induced systemic inflammation and disease but are not critical for the development of central nervous system disease in a mouse model of infection. Infection and Immunity. PMID 31818962 DOI: 10.1128/Iai.00787-19  0.575
2019 Auger JP, Payen S, Roy D, Dumesnil A, Segura M, Gottschalk M. Interactions of Streptococcus suis serotype 9 with host cells and role of the capsular polysaccharide: Comparison with serotypes 2 and 14. Plos One. 14: e0223864. PMID 31600314 DOI: 10.1371/Journal.Pone.0223864  0.641
2019 Goyette-Desjardins G, Lacouture S, Auger JP, Roy R, Gottschalk M, Segura M. Characterization and Protective Activity of Monoclonal Antibodies Directed against Serotype 2 Capsular Polysaccharide Obtained Using a Glycoconjugate. Pathogens (Basel, Switzerland). 8. PMID 31500262 DOI: 10.3390/Pathogens8030139  0.513
2019 Lavagna A, Auger JP, Dumesnil A, Roy D, Girardin SE, Gisch N, Segura M, Gottschalk M. Interleukin-1 signaling induced by Streptococcus suis serotype 2 is strain-dependent and contributes to bacterial clearance and inflammation during systemic disease in a mouse model of infection. Veterinary Research. 50: 52. PMID 31262357 DOI: 10.1186/S13567-019-0670-Y  0.629
2019 Allard MJ, Giraud A, Segura M, Sebire G. Sex-specific maternofetal innate immune responses triggered by group B Streptococci. Scientific Reports. 9: 8587. PMID 31197179 DOI: 10.1038/S41598-019-45029-X  0.335
2019 Auger JP, Boa AC, Segura M, Gottschalk M. Antigen I/II Participates in the Interactions of Serotype 9 With Phagocytes and the Development of Systemic Disease. Frontiers in Cellular and Infection Microbiology. 9: 124. PMID 31069179 DOI: 10.3389/Fcimb.2019.00124  0.589
2019 Auger JP, Benoit-Biancamano MO, Bédard C, Segura M, Gottschalk M. Differential role of MyD88 signaling in Streptococcus suis serotype 2-induced systemic and central nervous system diseases. International Immunology. PMID 30944920 DOI: 10.1093/Intimm/Dxz033  0.601
2019 Fourour S, Marois-Créhan C, Martelet L, Fablet C, Kempf I, Gottschalk M, Segura M. Intra-Species and Inter-Species Differences in Cytokine Production by Porcine Antigen-Presenting Cells Stimulated by , , and . Pathogens (Basel, Switzerland). 8. PMID 30884861 DOI: 10.3390/Pathogens8010034  0.54
2019 Allard MJ, Brochu ME, Bergeron JD, Segura M, Sébire G. Causal role of group B Streptococcus-induced acute chorioamnionitis in intrauterine growth retardation and cerebral palsy-like impairments. Journal of Developmental Origins of Health and Disease. 1-8. PMID 30626456 DOI: 10.1017/S2040174418001083  0.315
2018 Goyette-Desjardins G, Vinogradov E, Okura M, Takamatsu D, Gottschalk M, Segura M. Structure determination of Streptococcus suis serotypes 7 and 8 capsular polysaccharides and assignment of functions of the cps locus genes involved in their biosynthesis. Carbohydrate Research. 473: 36-45. PMID 30605786 DOI: 10.1016/j.carres.2018.12.009  0.475
2018 Goyette-Desjardins G, Vinogradov E, Okura M, Takamatsu D, Gottschalk M, Segura M. Streptococcus suis serotype 3 and serotype 18 capsular polysaccharides contain di-N-acetyl-bacillosamine. Carbohydrate Research. 466: 18-29. PMID 30014879 DOI: 10.1016/j.carres.2018.07.003  0.457
2018 Auger JP, Dolbec D, Roy D, Segura M, Gottschalk M. Role of the Streptococcus suis serotype 2 capsular polysaccharide in the interactions with dendritic cells is strain-dependent but remains critical for virulence. Plos One. 13: e0200453. PMID 30001363 DOI: 10.1371/Journal.Pone.0200453  0.601
2018 Letendre C, Auger JP, Lemire P, Galbas T, Gottschalk M, Thibodeau J, Segura M. Serotype 2 Infection Impairs Interleukin-12 Production and the MHC-II-Restricted Antigen Presentation Capacity of Dendritic Cells. Frontiers in Immunology. 9: 1199. PMID 29899744 DOI: 10.3389/Fimmu.2018.01199  0.562
2018 Roy D, Takamatsu D, Okura M, Goyette-Desjardins G, Van Calsteren MR, Dumesnil A, Gottschalk M, Segura M. Capsular Sialyltransferase Specificity Mediates Different Phenotypes in and Group B . Frontiers in Microbiology. 9: 545. PMID 29666608 DOI: 10.3389/Fmicb.2018.00545  0.527
2018 Vanderstock JM, Lecours MP, Lavoie-Lamoureux A, Gottschalk M, Segura M, Lavoie JP, Jean D. Phagocytosis, bacterial killing, and cytokine activation of circulating blood neutrophils in horses with severe equine asthma and control horses. American Journal of Veterinary Research. 79: 455-464. PMID 29583047 DOI: 10.2460/Ajvr.79.4.455  0.509
2018 Mathieu-Denoncourt A, Letendre C, Auger JP, Segura M, Aragon V, Lacouture S, Gottschalk M. Limited Interactions between Streptococcus Suis and Haemophilus Parasuis in In Vitro Co-Infection Studies. Pathogens (Basel, Switzerland). 7. PMID 29316613 DOI: 10.3390/Pathogens7010007  0.598
2017 Valanparambil RM, Tam M, Gros PP, Auger JP, Segura M, Gros P, Jardim A, Geary TG, Ozato K, Stevenson MM. IRF-8 regulates expansion of myeloid-derived suppressor cells and Foxp3+ regulatory T cells and modulates Th2 immune responses to gastrointestinal nematode infection. Plos Pathogens. 13: e1006647. PMID 28968468 DOI: 10.1371/Journal.Ppat.1006647  0.378
2017 Auger JP, Santinón A, Roy D, Mossman K, Xu J, Segura M, Gottschalk M. Type I Interferon Induced by Streptococcus suis Serotype 2 is Strain-Dependent and May Be Beneficial for Host Survival. Frontiers in Immunology. 8: 1039. PMID 28894449 DOI: 10.3389/Fimmu.2017.01039  0.636
2017 Lemire P, Galbas T, Thibodeau J, Segura M. Natural Killer Cell Functions during the Innate Immune Response to Pathogenic Streptococci. Frontiers in Microbiology. 8: 1196. PMID 28706510 DOI: 10.3389/Fmicb.2017.01196  0.453
2017 Roy D, Athey TBT, Auger JP, Goyette-Desjardins G, Van Calsteren MR, Takamatsu D, Okura M, Teatero S, Alcorlo M, Hermoso JA, Segura M, Gottschalk M, Fittipaldi N. A single amino acid polymorphism in the glycosyltransferase CpsK defines four Streptococcus suis serotypes. Scientific Reports. 7: 4066. PMID 28642597 DOI: 10.1038/S41598-017-04403-3  0.516
2017 Calzas C, Taillardet M, Fourati IS, Roy D, Gottschalk M, Soudeyns H, Defrance T, Segura M. Evaluation of the Immunomodulatory Properties of Streptococcus suis and Group B Streptococcus Capsular Polysaccharides on the Humoral Response. Pathogens (Basel, Switzerland). 6. PMID 28425925 DOI: 10.3390/Pathogens6020016  0.584
2017 Martelet L, Lacouture S, Goyette-Desjardins G, Beauchamp G, Surprenant C, Gottschalk M, Segura M. Porcine Dendritic Cells as an In Vitro Model to Assess the Immunological Behaviour of Streptococcus suis Subunit Vaccine Formulations and the Polarizing Effect of Adjuvants. Pathogens (Basel, Switzerland). 6. PMID 28327531 DOI: 10.3390/Pathogens6010013  0.536
2017 Segura M, Fittipaldi N, Calzas C, Gottschalk M. Critical Streptococcus suis Virulence Factors: Are They All Really Critical? Trends in Microbiology. PMID 28274524 DOI: 10.1016/J.Tim.2017.02.005  0.572
2017 Zheng H, Qiu X, Roy D, Segura M, Du P, Xu J, Gottschalk M. Genotyping and investigating capsular polysaccharide synthesis gene loci of non-serotypeable Streptococcus suis isolated from diseased pigs in Canada. Veterinary Research. 48: 10. PMID 28219415 DOI: 10.1186/S13567-017-0417-6  0.558
2016 Lecours MP, Letendre C, Clarke D, Lemire P, Galbas T, Benoit-Biancamano MO, Thibodeau J, Gottschalk M, Segura M. Immune-responsiveness of CD4(+) T cells during Streptococcus suis serotype 2 infection. Scientific Reports. 6: 38061. PMID 27905502 DOI: 10.1038/Srep38061  0.582
2016 Segura M, Calzas C, Grenier D, Gottschalk M. Initial steps of the pathogenesis of the infection caused by Streptococcus suis: fighting against non-specific defenses. Febs Letters. PMID 27539145 DOI: 10.1002/1873-3468.12364  0.62
2016 Teatero S, Lemire P, Dewar K, Wasserscheid J, Calzas C, Mallo GV, Li A, Athey TB, Segura M, Fittipaldi N. Genomic Recombination Leading to Decreased Virulence of Group B Streptococcus in a Mouse Model of Adult Invasive Disease. Pathogens (Basel, Switzerland). 5. PMID 27527222 DOI: 10.3390/Pathogens5030054  0.432
2016 Vinogradov E, Goyette-Desjardins G, Okura M, Takamatsu D, Gottschalk M, Segura M. Structure determination of Streptococcus suis serotype 9 capsular polysaccharide and assignment of functions of the cps locus genes involved in its biosynthesis. Carbohydrate Research. 433: 25-30. PMID 27423880 DOI: 10.1016/J.Carres.2016.07.005  0.546
2016 Auger JP, Fittipaldi N, Benoit-Biancamano MO, Segura M, Gottschalk M. Virulence Studies of Different Sequence Types and Geographical Origins of Streptococcus suis Serotype 2 in a Mouse Model of Infection. Pathogens (Basel, Switzerland). 5. PMID 27409640 DOI: 10.3390/Pathogens5030048  0.574
2016 Roy D, Grenier D, Segura M, Mathieu-Denoncourt A, Gottschalk M. Recruitment of Factor H to the Streptococcus suis Cell Surface is Multifactorial. Pathogens (Basel, Switzerland). 5. PMID 27399785 DOI: 10.3390/Pathogens5030047  0.547
2016 Hathroubi S, Beaudry F, Provost C, Martelet L, Segura M, Gagnon CA, Jacques M. Impact of Actinobacillus pleuropneumoniae biofilm mode of growth on the lipid A structures and stimulation of immune cells. Innate Immunity. PMID 27226465 DOI: 10.1177/1753425916649676  0.394
2016 Auray G, Lachance C, Wang Y, Gagnon CA, Segura M, Gottschalk M. Transcriptional Analysis of PRRSV-Infected Porcine Dendritic Cell Response to Streptococcus suis Infection Reveals Up-Regulation of Inflammatory-Related Genes Expression. Plos One. 11: e0156019. PMID 27213692 DOI: 10.1371/Journal.Pone.0156019  0.618
2016 Goyette-Desjardins G, Calzas C, Shiao TC, Neubauer A, Kempker J, Roy R, Gottschalk M, Segura M. Protection Against Streptococcus suis Serotype 2 Infection Using a Capsular Polysaccharide Glycoconjugate Vaccine. Infection and Immunity. PMID 27113360 DOI: 10.1128/Iai.00139-16  0.541
2016 Price NL, Goyette-Desjardins G, Nothaft H, Valguarnera E, Szymanski CM, Segura M, Feldman MF. Glycoengineered Outer Membrane Vesicles: A Novel Platform for Bacterial Vaccines. Scientific Reports. 6: 24931. PMID 27103188 DOI: 10.1038/Srep24931  0.368
2016 Clarke D, Letendre C, Lecours MP, Lemire P, Galbas T, Thibodeau J, Segura M. Group B Streptococcus Induces a Robust IFN-γ Response by CD4(+) T Cells in an In Vitro and In Vivo Model. Journal of Immunology Research. 2016: 5290604. PMID 26989699 DOI: 10.1155/2016/5290604  0.373
2016 Van Calsteren MR, Goyette-Desjardins G, Gagnon F, Okura M, Takamatsu D, Roy R, Gottschalk M, Segura M. Explaining the serological characteristics of Streptococcus suis serotypes 1 and 1/2 from their capsular polysaccharide structure and biosynthesis. The Journal of Biological Chemistry. PMID 26912653 DOI: 10.1074/Jbc.M115.700716  0.492
2015 Auger JP, Christodoulides M, Segura M, Xu J, Gottschalk M. Interactions of Streptococcus suis serotype 2 with human meningeal cells and astrocytes. Bmc Research Notes. 8: 607. PMID 26502903 DOI: 10.1186/S13104-015-1581-2  0.569
2015 Segura M. Streptococcus suis vaccines: candidate antigens and progress. Expert Review of Vaccines. 14: 1587-608. PMID 26468755 DOI: 10.1586/14760584.2015.1101349  0.377
2015 Goyette-Desjardins G, Roy R, Segura M. Murine Whole-Blood Opsonophagocytosis Assay to Evaluate Protection by Antibodies Raised Against Encapsulated Extracellular Bacteria. Methods in Molecular Biology (Clifton, N.J.). 1331: 81-92. PMID 26169736 DOI: 10.1007/978-1-4939-2874-3_6  0.386
2015 Roy D, Auger JP, Segura M, Fittipaldi N, Takamatsu D, Okura M, Gottschalk M. Role of the capsular polysaccharide as a virulence factor for Streptococcus suis serotype 14. Canadian Journal of Veterinary Research = Revue Canadienne De Recherche VéTéRinaire. 79: 141-6. PMID 25852230  0.501
2015 Calzas C, Lemire P, Auray G, Gerdts V, Gottschalk M, Segura M. Antibody response specific to the capsular polysaccharide is impaired in Streptococcus suis serotype 2-infected animals. Infection and Immunity. 83: 441-53. PMID 25385801 DOI: 10.1128/Iai.02427-14  0.584
2014 Goyette-Desjardins G, Auger JP, Xu J, Segura M, Gottschalk M. Streptococcus suis, an important pig pathogen and emerging zoonotic agent-an update on the worldwide distribution based on serotyping and sequence typing. Emerging Microbes & Infections. 3: e45. PMID 26038745 DOI: 10.1038/Emi.2014.45  0.608
2014 Lemire P, Roy D, Fittipaldi N, Okura M, Takamatsu D, Bergman E, Segura M. Implication of TLR- but not of NOD2-signaling pathways in dendritic cell activation by group B Streptococcus serotypes III and V. Plos One. 9: e113940. PMID 25436906 DOI: 10.1371/Journal.Pone.0113940  0.39
2014 Valanparambil RM, Segura M, Tam M, Jardim A, Geary TG, Stevenson MM. Production and analysis of immunomodulatory excretory-secretory products from the mouse gastrointestinal nematode Heligmosomoides polygyrus bakeri. Nature Protocols. 9: 2740-54. PMID 25375989 DOI: 10.1038/Nprot.2014.184  0.433
2014 Segura M, Zheng H, de Greeff A, Gao GF, Grenier D, Jiang Y, Lu C, Maskell D, Oishi K, Okura M, Osawa R, Schultsz C, Schwerk C, Sekizaki T, Smith H, et al. Latest developments on Streptococcus suis: an emerging zoonotic pathogen: part 2. Future Microbiology. 9: 587-91. PMID 24957086 DOI: 10.2217/Fmb.14.15  0.599
2014 Segura M, Zheng H, de Greeff A, Gao GF, Grenier D, Jiang Y, Lu C, Maskell D, Oishi K, Okura M, Osawa R, Schultsz C, Schwerk C, Sekizaki T, Smith H, et al. Latest developments on Streptococcus suis: an emerging zoonotic pathogen: part 1. Future Microbiology. 9: 441-4. PMID 24810343 DOI: 10.2217/Fmb.14.14  0.518
2014 Dang Y, Lachance C, Wang Y, Gagnon CA, Savard C, Segura M, Grenier D, Gottschalk M. Transcriptional approach to study porcine tracheal epithelial cells individually or dually infected with swine influenza virus and Streptococcus suis. Bmc Veterinary Research. 10: 86. PMID 24708855 DOI: 10.1186/1746-6148-10-86  0.564
2014 Lachance C, Segura M, Dominguez-Punaro MC, Wojewodka G, De Sanctis JB, Radzioch D, Gottschalk M. Deregulated balance of omega-6 and omega-3 polyunsaturated fatty acids following infection by the zoonotic pathogen Streptococcus suis. Infection and Immunity. 82: 1778-85. PMID 24549326 DOI: 10.1128/Iai.01524-13  0.606
2014 Savard C, Pinilla V, Provost C, Segura M, Gagnon CA, Chorfi Y. In vitro effect of deoxynivalenol (DON) mycotoxin on porcine reproductive and respiratory syndrome virus replication. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 65: 219-26. PMID 24394488 DOI: 10.1016/J.Fct.2013.12.043  0.367
2014 Lemire P, Segura M. The NOD2 receptor modulates cytokine response but does not alter the clinical outcome of Group B Streptococcus-infected mice Receptors and Clinical Investigation. 1. DOI: 10.14800/Rci.55  0.409
2013 Lemire P, Calzas C, Segura M. The NOD2 receptor does not play a major role in the pathogenesis of Group B Streptococcus in mice. Microbial Pathogenesis. 65: 41-7. PMID 24107312 DOI: 10.1016/J.Micpath.2013.09.006  0.431
2013 Wang Y, Gagnon CA, Savard C, Music N, Srednik M, Segura M, Lachance C, Bellehumeur C, Gottschalk M. Capsular sialic acid of Streptococcus suis serotype 2 binds to swine influenza virus and enhances bacterial interactions with virus-infected tracheal epithelial cells. Infection and Immunity. 81: 4498-508. PMID 24082069 DOI: 10.1128/Iai.00818-13  0.585
2013 Calzas C, Goyette-Desjardins G, Lemire P, Gagnon F, Lachance C, Van Calsteren MR, Segura M. Group B Streptococcus and Streptococcus suis capsular polysaccharides induce chemokine production by dendritic cells via Toll-like receptor 2- and MyD88-dependent and -independent pathways. Infection and Immunity. 81: 3106-18. PMID 23774593 DOI: 10.1128/Iai.00113-13  0.421
2013 Lachance C, Segura M, Gerber PP, Xu J, Gottschalk M. Toll-like receptor 2-independent host innate immune response against an epidemic strain of Streptococcus suis that causes a toxic shock-like syndrome in humans. Plos One. 8: e65031. PMID 23724118 DOI: 10.1371/Journal.Pone.0065031  0.619
2013 Van Calsteren MR, Gagnon F, Calzas C, Goyette-Desjardins G, Okura M, Takamatsu D, Gottschalk M, Segura M. Structure determination of Streptococcus suis serotype 14 capsular polysaccharide. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 91: 49-58. PMID 23527632 DOI: 10.1139/bcb-2012-0036  0.415
2013 Lachance C, Gottschalk M, Gerber PP, Lemire P, Xu J, Segura M. Exacerbated type II interferon response drives hypervirulence and toxic shock by an emergent epidemic strain of Streptococcus suis. Infection and Immunity. 81: 1928-39. PMID 23509145 DOI: 10.1128/Iai.01317-12  0.623
2013 Zheng H, Sun H, Dominguez-Punaro Mde L, Bai X, Ji S, Segura M, Xu J. Evaluation of the pathogenesis of meningitis caused by Streptococcus suis sequence type 7 using the infection of BV2 microglial cells. Journal of Medical Microbiology. 62: 360-8. PMID 23222863 DOI: 10.1099/Jmm.0.046698-0  0.512
2012 Lecours MP, Segura M, Fittipaldi N, Rivest S, Gottschalk M. Immune receptors involved in Streptococcus suis recognition by dendritic cells. Plos One. 7: e44746. PMID 22984550 DOI: 10.1371/Journal.Pone.0044746  0.548
2012 Lemire P, Houde M, Segura M. Encapsulated group B Streptococcus modulates dendritic cell functions via lipid rafts and clathrin-mediated endocytosis. Cellular Microbiology. 14: 1707-19. PMID 22735044 DOI: 10.1111/J.1462-5822.2012.01830.X  0.376
2012 Lemire P, Houde M, Lecours MP, Fittipaldi N, Segura M. Role of capsular polysaccharide in Group B Streptococccus interactions with dendritic cells. Microbes and Infection / Institut Pasteur. 14: 1064-76. PMID 22683668 DOI: 10.1016/J.Micinf.2012.05.015  0.418
2012 Lecours MP, Fittipaldi N, Takamatsu D, Okura M, Segura M, Goyette-Desjardins G, Van Calsteren MR, Gottschalk M. Sialylation of Streptococcus suis serotype 2 is essential for capsule expression but is not responsible for the main capsular epitope. Microbes and Infection / Institut Pasteur. 14: 941-50. PMID 22521569 DOI: 10.1016/J.Micinf.2012.03.008  0.612
2012 Segura M. Fisher scientific award lecture - the capsular polysaccharides of Group B Streptococcus and Streptococcus suis differently modulate bacterial interactions with dendritic cells. Canadian Journal of Microbiology. 58: 249-60. PMID 22356626 DOI: 10.1139/W2012-003  0.495
2012 Fittipaldi N, Segura M, Grenier D, Gottschalk M. Virulence factors involved in the pathogenesis of the infection caused by the swine pathogen and zoonotic agent Streptococcus suis. Future Microbiology. 7: 259-79. PMID 22324994 DOI: 10.2217/Fmb.11.149  0.636
2012 Houde M, Gottschalk M, Gagnon F, Van Calsteren MR, Segura M. Streptococcus suis capsular polysaccharide inhibits phagocytosis through destabilization of lipid microdomains and prevents lactosylceramide-dependent recognition. Infection and Immunity. 80: 506-17. PMID 22124659 DOI: 10.1128/Iai.05734-11  0.618
2012 Zheng H, Luo X, Segura M, Sun H, Ye C, Gottschalk M, Xu J. The role of toll-like receptors in the pathogenesis of Streptococcus suis. Veterinary Microbiology. 156: 147-56. PMID 22055206 DOI: 10.1016/J.Vetmic.2011.10.014  0.617
2011 Moreno Y, Gros PP, Tam M, Segura M, Valanparambil R, Geary TG, Stevenson MM. Proteomic analysis of excretory-secretory products of Heligmosomoides polygyrus assessed with next-generation sequencing transcriptomic information. Plos Neglected Tropical Diseases. 5: e1370. PMID 22039562 DOI: 10.1371/Journal.Pntd.0001370  0.313
2011 Lecours MP, Gottschalk M, Houde M, Lemire P, Fittipaldi N, Segura M. Critical role for Streptococcus suis cell wall modifications and suilysin in resistance to complement-dependent killing by dendritic cells. The Journal of Infectious Diseases. 204: 919-29. PMID 21849289 DOI: 10.1093/Infdis/Jir415  0.578
2011 Lecours MP, Segura M, Lachance C, Mussa T, Surprenant C, Montoya M, Gottschalk M. Characterization of porcine dendritic cell response to Streptococcus suis. Veterinary Research. 42: 72. PMID 21635729 DOI: 10.1186/1297-9716-42-72  0.6
2011 Zheng X, Zheng H, Lan R, Ye C, Wang Y, Zhang J, Jing H, Chen C, Segura M, Gottschalk M, Xu J. Identification of genes and genomic islands correlated with high pathogenicity in Streptococcus suis using whole genome tiling microarrays. Plos One. 6: e17987. PMID 21479213 DOI: 10.1371/Journal.Pone.0017987  0.557
2011 Zheng H, Punaro MC, Segura M, Lachance C, Rivest S, Xu J, Houde M, Gottschalk M. Toll-like receptor 2 is partially involved in the activation of murine astrocytes by Streptococcus suis, an important zoonotic agent of meningitis. Journal of Neuroimmunology. 234: 71-83. PMID 21429596 DOI: 10.1016/J.Jneuroim.2011.02.005  0.588
2010 Domínguez-Punaro Mde L, Segura M, Contreras I, Lachance C, Houde M, Lecours MP, Olivier M, Gottschalk M. In vitro characterization of the microglial inflammatory response to Streptococcus suis, an important emerging zoonotic agent of meningitis. Infection and Immunity. 78: 5074-85. PMID 20876287 DOI: 10.1128/Iai.00698-10  0.623
2010 Gottschalk M, Dubreuil JD, Esgleas M, Harel J, Segura M. The alpha-enolase of Streptococcus suis: a previously well-known and well-characterized protein. The Journal of Infectious Diseases. 201: 1775-6; author reply. PMID 20429669 DOI: 10.1086/652417  0.432
2010 Gottschalk M, Xu J, Calzas C, Segura M. Streptococcus suis: a new emerging or an old neglected zoonotic pathogen? Future Microbiology. 5: 371-91. PMID 20210549 DOI: 10.2217/Fmb.10.2  0.58
2010 Gottschalk M, Xu J, Lecours M, Grenier D, Fittipaldi N, Segura M. Streptococcus suis Infections in Humans: What is the prognosis for Western countries? (Part I) Clinical Microbiology Newsletter. 32: 89-96. DOI: 10.1016/J.Clinmicnews.2010.05.005  0.597
2009 Vanier G, Segura M, Lecours MP, Grenier D, Gottschalk M. Porcine brain microvascular endothelial cell-derived interleukin-8 is first induced and then degraded by Streptococcus suis. Microbial Pathogenesis. 46: 135-43. PMID 19100324 DOI: 10.1016/J.Micpath.2008.11.004  0.576
2009 Segura M. Streptococcus suis: an emerging human threat. The Journal of Infectious Diseases. 199: 4-6. PMID 19016626 DOI: 10.1086/594371  0.472
2009 Vanier G, Fittipaldi N, Slater JD, de la Cruz Domínguez-Punaro M, Rycroft AN, Segura M, Maskell DJ, Gottschalk M. New putative virulence factors of Streptococcus suis involved in invasion of porcine brain microvascular endothelial cells. Microbial Pathogenesis. 46: 13-20. PMID 18984036 DOI: 10.1016/J.Micpath.2008.10.003  0.601
2008 Zheng H, Ye C, Segura M, Gottschalk M, Xu J. Mitogenic effect contributes to increased virulence of Streptococcus suis sequence type 7 to cause streptococcal toxic shock-like syndrome. Clinical and Experimental Immunology. 153: 385-91. PMID 18803762 DOI: 10.1111/J.1365-2249.2008.03722.X  0.554
2008 Domínguez-Punaro Mde L, Segura M, Radzioch D, Rivest S, Gottschalk M. Comparison of the susceptibilities of C57BL/6 and A/J mouse strains to Streptococcus suis serotype 2 infection. Infection and Immunity. 76: 3901-10. PMID 18573893 DOI: 10.1128/Iai.00350-08  0.585
2007 Gottschalk M, Segura M, Xu J. Streptococcus suis infections in humans: the Chinese experience and the situation in North America. Animal Health Research Reviews / Conference of Research Workers in Animal Diseases. 8: 29-45. PMID 17692141 DOI: 10.1017/S1466252307001247  0.596
2007 Domínguez-Punaro MC, Segura M, Plante MM, Lacouture S, Rivest S, Gottschalk M. Streptococcus suis serotype 2, an important swine and human pathogen, induces strong systemic and cerebral inflammatory responses in a mouse model of infection. Journal of Immunology (Baltimore, Md. : 1950). 179: 1842-54. PMID 17641051 DOI: 10.4049/Jimmunol.179.3.1842  0.555
2007 Vanier G, Segura M, Gottschalk M. Characterization of the invasion of porcine endothelial cells by Streptococcus suis serotype 2. Canadian Journal of Veterinary Research = Revue Canadienne De Recherche VéTéRinaire. 71: 81-9. PMID 17479770  0.513
2007 Graveline R, Segura M, Radzioch D, Gottschalk M. TLR2-dependent recognition of Streptococcus suis is modulated by the presence of capsular polysaccharide which modifies macrophage responsiveness. International Immunology. 19: 375-89. PMID 17307800 DOI: 10.1093/Intimm/Dxm003  0.539
2006 Ye C, Zhu X, Jing H, Du H, Segura M, Zheng H, Kan B, Wang L, Bai X, Zhou Y, Cui Z, Zhang S, Jin D, Sun N, Luo X, et al. Streptococcus suis sequence type 7 outbreak, Sichuan, China. Emerging Infectious Diseases. 12: 1203-8. PMID 16965698 DOI: 10.3201/Eid1208.060232  0.564
2006 Chabot-Roy G, Willson P, Segura M, Lacouture S, Gottschalk M. Phagocytosis and killing of Streptococcus suis by porcine neutrophils. Microbial Pathogenesis. 41: 21-32. PMID 16714092 DOI: 10.1016/J.Micpath.2006.04.001  0.645
2006 Segura M, Vanier G, Al-Numani D, Lacouture S, Olivier M, Gottschalk M. Proinflammatory cytokine and chemokine modulation by Streptococcus suis in a whole-blood culture system. Fems Immunology and Medical Microbiology. 47: 92-106. PMID 16706792 DOI: 10.1111/J.1574-695X.2006.00067.X  0.614
2005 Su Z, Segura M, Morgan K, Loredo-Osti JC, Stevenson MM. Impairment of protective immunity to blood-stage malaria by concurrent nematode infection. Infection and Immunity. 73: 3531-9. PMID 15908382 DOI: 10.1128/Iai.73.6.3531-3539.2005  0.396
2004 Segura M, Gottschalk M, Olivier M. Encapsulated Streptococcus suis inhibits activation of signaling pathways involved in phagocytosis. Infection and Immunity. 72: 5322-30. PMID 15322029 DOI: 10.1128/Iai.72.9.5322-5330.2004  0.481
2004 Vanier G, Segura M, Friedl P, Lacouture S, Gottschalk M. Invasion of porcine brain microvascular endothelial cells by Streptococcus suis serotype 2. Infection and Immunity. 72: 1441-9. PMID 14977949 DOI: 10.1128/Iai.72.3.1441-1449.2004  0.595
2004 Segura M, Gottschalk M. Extracellular virulence factors of streptococci associated with animal diseases. Frontiers in Bioscience : a Journal and Virtual Library. 9: 1157-88. PMID 14977535 DOI: 10.2741/1287  0.581
2003 Al-Numani D, Segura M, Doré M, Gottschalk M. Up-regulation of ICAM-1, CD11a/CD18 and CD11c/CD18 on human THP-1 monocytes stimulated by Streptococcus suis serotype 2. Clinical and Experimental Immunology. 133: 67-77. PMID 12823280 DOI: 10.1046/J.1365-2249.2003.02189.X  0.555
2003 Vadeboncoeur N, Segura M, Al-Numani D, Vanier G, Gottschalk M. Pro-inflammatory cytokine and chemokine release by human brain microvascular endothelial cells stimulated by Streptococcus suis serotype 2. Fems Immunology and Medical Microbiology. 35: 49-58. PMID 12589957 DOI: 10.1111/J.1574-695X.2003.Tb00648.X  0.579
2002 Segura M, Gottschalk M. Streptococcus suis interactions with the murine macrophage cell line J774: adhesion and cytotoxicity. Infection and Immunity. 70: 4312-22. PMID 12117940 DOI: 10.1128/Iai.70.8.4312-4322.2002  0.632
2002 Segura M, Vadeboncoeur N, Gottschalk M. CD14-dependent and -independent cytokine and chemokine production by human THP-1 monocytes stimulated by Streptococcus suis capsular type 2. Clinical and Experimental Immunology. 127: 243-54. PMID 11876746 DOI: 10.1046/J.1365-2249.2002.01768.X  0.561
2000 Gottschalk M, Segura M. The pathogenesis of the meningitis caused by Streptococcus suis: the unresolved questions. Veterinary Microbiology. 76: 259-272. PMID 10973700 DOI: 10.1016/S0378-1135(00)00250-9  0.637
2000 Lalonde M, Segura M, Lacouture S, Gottschalk M. Interactions between Streptococcus suis serotype 2 and different epithelial cell lines Microbiology. 146: 1913-1921. PMID 10931895 DOI: 10.1099/00221287-146-8-1913  0.626
1999 Segura M, Stankova J, Gottschalk M. Heat-killed Streptococcus suis capsular type 2 strains stimulate tumor necrosis factor alpha and interleukin-6 production by murine macrophages. Infection and Immunity. 67: 4646-54. PMID 10456911 DOI: 10.1128/Iai.67.9.4646-4654.1999  0.567
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