| Year |
Citation |
Score |
| 2018 |
Langlais D, Cencic R, Moradin N, Kennedy JM, Ayi K, Brown LE, Crandall I, Tarry MJ, Schmeing M, Kain KC, Porco JA, Pelletier J, Gros P. Rocaglates as dual-targeting agents for experimental cerebral malaria. Proceedings of the National Academy of Sciences of the United States of America. PMID 29463745 DOI: 10.1073/pnas.1713000115 |
0.32 |
|
| 2017 |
Fodil N, Moradin N, Leung V, Olivier JF, Radovanovic I, Jeyakumar T, Flores Molina M, McFarquhar A, Cayrol R, Bozec D, Shoukry NH, Kubo M, Dimitrieva J, Louis E, Theatre E, ... ... Gros P, et al. CCDC88B is required for pathogenesis of inflammatory bowel disease. Nature Communications. 8: 932. PMID 29030607 DOI: 10.1038/s41467-017-01381-y |
0.48 |
|
| 2017 |
Valanparambil RM, Tam M, Gros PP, Auger JP, Segura M, Gros P, Jardim A, Geary TG, Ozato K, Stevenson MM. IRF-8 regulates expansion of myeloid-derived suppressor cells and Foxp3+ regulatory T cells and modulates Th2 immune responses to gastrointestinal nematode infection. Plos Pathogens. 13: e1006647. PMID 28968468 DOI: 10.1371/journal.ppat.1006647 |
0.6 |
|
| 2017 |
Laroque A, Min-Oo G, Tam M, Ponka P, Stevenson MM, Gros P. The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria. Plos One. 12: e0177818. PMID 28542307 DOI: 10.1371/journal.pone.0177818 |
0.6 |
|
| 2016 |
Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, ... ... Gros P, et al. Erratum: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation. Nature Immunology. 17: 1479. PMID 27849203 DOI: 10.1038/ni1216-1479c |
0.48 |
|
| 2016 |
Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, ... ... Gros P, et al. USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation. Nature Immunology. PMID 27721430 DOI: 10.1038/ni.3581 |
1 |
|
| 2016 |
Moradin N, Torre S, Gauthier S, Tam M, Hawari J, Vandercruyssen K, De Spiegeleer B, Fortin A, Stevenson MM, Gros P. Cysteamine broadly improves the anti-plasmodial activity of artemisinins against murine blood stage and cerebral malaria. Malaria Journal. 15: 260. PMID 27150250 DOI: 10.1186/s12936-016-1317-3 |
1 |
|
| 2015 |
van Bruggen R, Gualtieri C, Iliescu A, Louicharoen Cheepsunthorn C, Mungkalasut P, Trape JF, Modiano D, Sodiomon Sirima B, Singhasivanon P, Lathrop M, Sakuntabhai A, Bureau JF, Gros P. Modulation of Malaria Phenotypes by Pyruvate Kinase (PKLR) Variants in a Thai Population. Plos One. 10: e0144555. PMID 26658699 DOI: 10.1371/journal.pone.0144555 |
1 |
|
| 2015 |
Van Der Kraak L, Gros P, Beauchemin N. Colitis-associated colon cancer: Is it in your genes? World Journal of Gastroenterology. 21: 11688-99. PMID 26556996 DOI: 10.3748/wjg.v21.i41.11688 |
1 |
|
| 2015 |
Leung V, Iliescu A, Jolicoeur C, Gravel M, Apuzzo S, Torban E, Cayouette M, Gros P. The planar cell polarity protein Vangl2 is required for retinal axon guidance. Developmental Neurobiology. PMID 25990804 DOI: 10.1002/dneu.22305 |
1 |
|
| 2015 |
Seo JH, Zilber Y, Babayeva S, Liu J, Kyriakopoulos P, De Marco P, Merello E, Capra V, Gros P, Torban E. Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans. Human Molecular Genetics. 24: 3893. PMID 25954026 DOI: 10.1093/hmg/ddv131 |
0.32 |
|
| 2015 |
Belle JI, Langlais D, Petrov JC, Pardo M, Jones RG, Gros P, Nijnik A. p53 mediates loss of hematopoietic stem cell function and lymphopenia in Mysm1 deficiency. Blood. 125: 2344-8. PMID 25710881 DOI: 10.1182/blood-2014-05-574111 |
1 |
|
| 2015 |
Zhang X, Bogunovic D, Payelle-Brogard B, Francois-Newton V, Speer SD, Yuan C, Volpi S, Li Z, Sanal O, Mansouri D, Tezcan I, Rice GI, Chen C, Mansouri N, Mahdaviani SA, ... ... Gros P, et al. Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation. Nature. 517: 89-93. PMID 25307056 DOI: 10.1038/nature13801 |
1 |
|
| 2015 |
Rocque BL, Babayeva S, Li J, Leung V, Nezvitsky L, Cybulsky AV, Gros P, Torban E. Deficiency of the planar cell polarity protein Vangl2 in podocytes affects glomerular morphogenesis and increases susceptibility to injury. Journal of the American Society of Nephrology : Jasn. 26: 576-86. PMID 25145929 DOI: 10.1681/ASN.2014040340 |
1 |
|
| 2014 |
Fodil N, Langlais D, Moussa P, Boivin GA, Di Pietrantonio T, Radovanovic I, Dumaine A, Blanchette M, Schurr E, Gros P, Vidal SM. Specific dysregulation of IFNγ production by natural killer cells confers susceptibility to viral infection. Plos Pathogens. 10: e1004511. PMID 25473962 DOI: 10.1371/journal.ppat.1004511 |
1 |
|
| 2014 |
Kennedy JM, Fodil N, Torre S, Bongfen SE, Olivier JF, Leung V, Langlais D, Meunier C, Berghout J, Langat P, Schwartzentruber J, Majewski J, Lathrop M, Vidal SM, Gros P. CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation. The Journal of Experimental Medicine. 211: 2519-35. PMID 25403443 DOI: 10.1084/jem.20140455 |
1 |
|
| 2014 |
Caignard G, Eva MM, van Bruggen R, Eveleigh R, Bourque G, Malo D, Gros P, Vidal SM. Mouse ENU Mutagenesis to Understand Immunity to Infection: Methods, Selected Examples, and Perspectives. Genes. 5: 887-925. PMID 25268389 DOI: 10.3390/genes5040887 |
1 |
|
| 2014 |
Salem S, Langlais D, Lefebvre F, Bourque G, Bigley V, Haniffa M, Casanova JL, Burk D, Berghuis A, Butler KM, Leahy TR, Hambleton S, Gros P. Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8(K108E) mutation. Blood. 124: 1894-904. PMID 25122610 DOI: 10.1182/blood-2014-04-570879 |
1 |
|
| 2014 |
Iliescu A, Gravel M, Horth C, Gros P. Independent mutations at Arg181 and Arg274 of Vangl proteins that are associated with neural tube defects in humans decrease protein stability and impair membrane targeting. Biochemistry. 53: 5356-64. PMID 25068569 DOI: 10.1021/bi500400g |
1 |
|
| 2014 |
Gros P, Belkaid Y. Editorial overview: Host pathogens. Current Opinion in Immunology. 29: iv-vi. PMID 25027097 DOI: 10.1016/j.coi.2014.06.008 |
1 |
|
| 2014 |
Radovanovic I, Leung V, Iliescu A, Bongfen SE, Mullick A, Langlais D, Gros P. Genetic control of susceptibility to Candida albicans in SM/J mice. Journal of Immunology (Baltimore, Md. : 1950). 193: 1290-300. PMID 24973457 DOI: 10.4049/jimmunol.1400783 |
1 |
|
| 2014 |
Salem S, Gao C, Li A, Wang H, Nguyen-Yamamoto L, Goltzman D, Henderson JE, Gros P. A novel role for interferon regulatory factor 1 (IRF1) in regulation of bone metabolism. Journal of Cellular and Molecular Medicine. 18: 1588-98. PMID 24954358 DOI: 10.1111/jcmm.12327 |
1 |
|
| 2014 |
Dauphinee SM, Richer E, Eva MM, McIntosh F, Paquet M, Dangoor D, Burkart C, Zhang DE, Gruenheid S, Gros P, Behr M, Malo D. Contribution of increased ISG15, ISGylation and deregulated type I IFN signaling in Usp18 mutant mice during the course of bacterial infections. Genes and Immunity. 15: 282-92. PMID 24807690 DOI: 10.1038/gene.2014.17 |
1 |
|
| 2014 |
Meadows DN, Pyzik M, Wu Q, Torre S, Gros P, Vidal SM, Rozen R. Increased resistance to malaria in mice with methylenetetrahydrofolate reductase (Mthfr) deficiency suggests a mechanism for selection of the MTHFR 677C>T (c.665C>T) variant. Human Mutation. 35: 594-600. PMID 24616178 DOI: 10.1002/humu.22533 |
1 |
|
| 2014 |
Iliescu A, Gros P. The intracellular carboxyl terminal domain of Vangl proteins contains plasma membrane targeting signals. Protein Science : a Publication of the Protein Society. 23: 337-43. PMID 24452931 DOI: 10.1002/pro.2432 |
1 |
|
| 2013 |
Byun M, Ma CS, Akçay A, Pedergnana V, Palendira U, Myoung J, Avery DT, Liu Y, Abhyankar A, Lorenzo L, Schmidt M, Lim HK, Cassar O, Migaud M, Rozenberg F, ... ... Gros P, et al. Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood. The Journal of Experimental Medicine. 210: 1743-59. PMID 23897980 DOI: 10.1084/jem.20130592 |
1 |
|
| 2013 |
Berghout J, Langlais D, Radovanovic I, Tam M, MacMicking JD, Stevenson MM, Gros P. Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria. Plos Pathogens. 9: e1003491. PMID 23853600 DOI: 10.1371/journal.ppat.1003491 |
1 |
|
| 2013 |
Meunier C, Van Der Kraak L, Turbide C, Groulx N, Labouba I, Cingolani P, Blanchette M, Yeretssian G, Mes-Masson AM, Saleh M, Beauchemin N, Gros P. Positional mapping and candidate gene analysis of the mouse Ccs3 locus that regulates differential susceptibility to carcinogen-induced colorectal cancer. Plos One. 8: e58733. PMID 23516545 DOI: 10.1371/journal.pone.0058733 |
1 |
|
| 2013 |
Salem S, Gros P. Genetic determinants of susceptibility to Mycobacterial infections: IRF8, a new kid on the block. Advances in Experimental Medicine and Biology. 783: 45-80. PMID 23468103 DOI: 10.1007/978-1-4614-6111-1_3 |
1 |
|
| 2012 |
Torban E, Iliescu A, Gros P. An expanding role of Vangl proteins in embryonic development. Current Topics in Developmental Biology. 101: 237-61. PMID 23140632 DOI: 10.1016/B978-0-12-394592-1.00005-3 |
1 |
|
| 2012 |
Idaghdour Y, Quinlan J, Goulet JP, Berghout J, Gbeha E, Bruat V, de Malliard T, Grenier JC, Gomez S, Gros P, Rahimy MC, Sanni A, Awadalla P. Evidence for additive and interaction effects of host genotype and infection in malaria. Proceedings of the National Academy of Sciences of the United States of America. 109: 16786-93. PMID 22949651 DOI: 10.1073/pnas.1204945109 |
1 |
|
| 2012 |
Bogunovic D, Byun M, Durfee LA, Abhyankar A, Sanal O, Mansouri D, Salem S, Radovanovic I, Grant AV, Adimi P, Mansouri N, Okada S, Bryant VL, Kong XF, Kreins A, ... ... Gros P, et al. Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency. Science (New York, N.Y.). 337: 1684-8. PMID 22859821 DOI: 10.1126/science.1224026 |
1 |
|
| 2012 |
Bongfen SE, Rodrigue-Gervais IG, Berghout J, Torre S, Cingolani P, Wiltshire SA, Leiva-Torres GA, Letourneau L, Sladek R, Blanchette M, Lathrop M, Behr MA, Gruenheid S, Vidal SM, Saleh M, ... Gros P, et al. An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria. Plos One. 7: e31012. PMID 22363534 DOI: 10.1371/journal.pone.0031012 |
1 |
|
| 2011 |
Ramirez-Aquino R, Radovanovic I, Fortin A, Sciutto-Conde E, Fragoso-González G, Gros P, Aguilar-Delfin I. Identification of loci controlling restriction of parasite growth in experimental Taenia crassiceps cysticercosis. Plos Neglected Tropical Diseases. 5: e1435. PMID 22206032 DOI: 10.1371/journal.pntd.0001435 |
1 |
|
| 2011 |
Seo JH, Zilber Y, Babayeva S, Liu J, Kyriakopoulos P, De Marco P, Merello E, Capra V, Gros P, Torban E. Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans. Human Molecular Genetics. 20: 4324-33. PMID 21840926 DOI: 10.1093/hmg/ddr359 |
1 |
|
| 2011 |
Fortier A, Faucher SP, Diallo K, Gros P. Global cellular changes induced by Legionella pneumophila infection of bone marrow-derived macrophages. Immunobiology. 216: 1274-85. PMID 21794945 DOI: 10.1016/j.imbio.2011.06.008 |
1 |
|
| 2011 |
Marquis JF, Kapoustina O, Langlais D, Ruddy R, Dufour CR, Kim BH, MacMicking JD, Giguère V, Gros P. Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis. Plos Genetics. 7: e1002097. PMID 21731497 DOI: 10.1371/journal.pgen.1002097 |
1 |
|
| 2011 |
Meunier C, Kwan T, Turbide C, Beauchemin N, Gros P. Genetic control of susceptibility to carcinogen-induced colorectal cancer in mice: the Ccs3 and Ccs5 loci regulate different aspects of tumorigenesis. Cell Cycle (Georgetown, Tex.). 10: 1739-49. PMID 21543896 |
0.88 |
|
| 2011 |
Radovanovic I, Mullick A, Gros P. Genetic control of susceptibility to infection with Candida albicans in mice. Plos One. 6: e18957. PMID 21533108 DOI: 10.1371/journal.pone.0018957 |
1 |
|
| 2011 |
Hambleton S, Salem S, Bustamante J, Bigley V, Boisson-Dupuis S, Azevedo J, Fortin A, Haniffa M, Ceron-Gutierrez L, Bacon CM, Menon G, Trouillet C, McDonald D, Carey P, Ginhoux F, ... ... Gros P, et al. IRF8 mutations and human dendritic-cell immunodeficiency. The New England Journal of Medicine. 365: 127-38. PMID 21524210 DOI: 10.1056/NEJMoa1100066 |
1 |
|
| 2011 |
Min-Oo G, Gros P. Genetic analysis in mice identifies cysteamine as a novel partner for artemisinin in the treatment of malaria. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 22: 486-94. PMID 21437649 DOI: 10.1007/s00335-011-9316-8 |
1 |
|
| 2011 |
Guyot MC, Bosoi CM, Kharfallah F, Reynolds A, Drapeau P, Justice M, Gros P, Kibar Z. A novel hypomorphic Looptail allele at the planar cell polarity Vangl2 gene. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 839-49. PMID 21404367 DOI: 10.1002/dvdy.22577 |
1 |
|
| 2011 |
Iliescu A, Gravel M, Horth C, Apuzzo S, Gros P. Transmembrane topology of mammalian planar cell polarity protein Vangl1. Biochemistry. 50: 2274-82. PMID 21291170 DOI: 10.1021/bi101767a |
1 |
|
| 2011 |
Iliescu A, Gravel M, Horth C, Kibar Z, Gros P. Loss of membrane targeting of Vangl proteins causes neural tube defects. Biochemistry. 50: 795-804. PMID 21142127 DOI: 10.1021/bi101286d |
1 |
|
| 2011 |
Longley R, Smith C, Fortin A, Berghout J, McMorran B, Burgio G, Foote S, Gros P. Host resistance to malaria: using mouse models to explore the host response. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 22: 32-42. PMID 21116636 DOI: 10.1007/s00335-010-9302-6 |
1 |
|
| 2010 |
Gruenheid S, Gros P. Forward genetic dissection of innate response to infection in inbred mouse strains: selected success stories. Clinical and Experimental Immunology. 162: 393-401. PMID 21070206 DOI: 10.1111/j.1365-2249.2010.04249.x |
1 |
|
| 2010 |
Min-Oo G, Fortin A, Poulin JF, Gros P. Cysteamine, the molecule used to treat cystinosis, potentiates the antimalarial efficacy of artemisinin. Antimicrobial Agents and Chemotherapy. 54: 3262-70. PMID 20479197 DOI: 10.1128/AAC.01719-09 |
1 |
|
| 2010 |
Murawski IJ, Maina RW, Malo D, Guay-Woodford LM, Gros P, Fujiwara M, Morgan K, Gupta IR. The C3H/HeJ inbred mouse is a model of vesico-ureteric reflux with a susceptibility locus on chromosome 12. Kidney International. 78: 269-78. PMID 20407478 DOI: 10.1038/ki.2010.110 |
1 |
|
| 2010 |
Stevenson MM, Gros P, Olivier M, Fortin A, Serghides L. Cerebral malaria: human versus mouse studies. Trends in Parasitology. 26: 274-5. PMID 20382077 DOI: 10.1016/j.pt.2010.03.008 |
1 |
|
| 2010 |
Gravel M, Iliescu A, Horth C, Apuzzo S, Gros P. Molecular and cellular mechanisms underlying neural tube defects in the loop-tail mutant mouse Biochemistry. 49: 3445-3455. PMID 20329788 DOI: 10.1021/bi902180m |
1 |
|
| 2010 |
Min-Oo G, Ayi K, Bongfen SE, Tam M, Radovanovic I, Gauthier S, Santiago H, Rothfuchs AG, Roffê E, Sher A, Mullick A, Fortin A, Stevenson MM, Kain KC, Gros P. Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium. Experimental Parasitology. 125: 315-24. PMID 20219464 DOI: 10.1016/j.exppara.2010.02.009 |
1 |
|
| 2010 |
Behr M, Schurr E, Gros P. TB: screening for responses to a vile visitor. Cell. 140: 615-8. PMID 20211131 DOI: 10.1016/j.cell.2010.02.030 |
0.32 |
|
| 2010 |
Reynolds A, McDearmid JR, Lachance S, De Marco P, Merello E, Capra V, Gros P, Drapeau P, Kibar Z. VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish. Mechanisms of Development. 127: 385-92. PMID 20043994 DOI: 10.1016/j.mod.2009.12.002 |
1 |
|
| 2010 |
Meunier C, Cai J, Fortin A, Kwan T, Marquis JF, Turbide C, Van Der Kraak L, Jothy S, Beauchemin N, Gros P. Characterization of a major colon cancer susceptibility locus (Ccs3) on mouse chromosome 3 Oncogene. 29: 647-661. PMID 19915610 DOI: 10.1038/onc.2009.369 |
1 |
|
| 2009 |
Schurr E, Gros P. A common genetic fingerprint in leprosy and Crohn's disease? The New England Journal of Medicine. 361: 2666-8. PMID 20018963 DOI: 10.1056/NEJMe0910690 |
1 |
|
| 2009 |
Ayi K, Liles WC, Gros P, Kain KC. Adenosine triphosphate depletion of erythrocytes simulates the phenotype associated with pyruvate kinase deficiency and confers protection against Plasmodium falciparum in vitro. The Journal of Infectious Diseases. 200: 1289-99. PMID 19743919 DOI: 10.1086/605843 |
1 |
|
| 2009 |
Fortier A, Doiron K, Saleh M, Grinstein S, Gros P. Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4. Infection and Immunity. 77: 4794-805. PMID 19720760 DOI: 10.1128/IAI.01546-08 |
0.4 |
|
| 2009 |
Czachorowski M, Lam-Yuk-Tseung S, Cellier M, Gros P. Transmembrane topology of the mammalian Slc11a2 iron transporter. Biochemistry. 48: 8422-34. PMID 19621945 DOI: 10.1021/bi900606y |
0.4 |
|
| 2009 |
Kibar Z, Bosoi CM, Kooistra M, Salem S, Finnell RH, De Marco P, Merello E, Bassuk AG, Capra V, Gros P. Novel mutations in VANGL1 in neural tube defects. Human Mutation. 30: E706-15. PMID 19319979 DOI: 10.1002/humu.21026 |
1 |
|
| 2009 |
Marquis JF, Lacourse R, Ryan L, North RJ, Gros P. Genetic and functional characterization of the mouse Trl3 locus in defense against tuberculosis. Journal of Immunology (Baltimore, Md. : 1950). 182: 3757-67. PMID 19265154 DOI: 10.4049/jimmunol.0802094 |
1 |
|
| 2009 |
Marquis JF, LaCourse R, Ryan L, North RJ, Gros P. Disseminated and rapidly fatal tuberculosis in mice bearing a defective allele at IFN regulatory factor 8. Journal of Immunology (Baltimore, Md. : 1950). 182: 3008-15. PMID 19234196 DOI: 10.4049/jimmunol.0800680 |
1 |
|
| 2008 |
Divangahi M, Mostowy S, Coulombe F, Kozak R, Guillot L, Veyrier F, Kobayashi KS, Flavell RA, Gros P, Behr MA. NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity. Journal of Immunology (Baltimore, Md. : 1950). 181: 7157-65. PMID 18981137 |
1 |
|
| 2008 |
Marquis JF, Gros P. Genetic analysis of resistance to infections in mice: A/J meets C57BL/6J Current Topics in Microbiology and Immunology. 321: 27-57. PMID 18727486 DOI: 10.1007/978-3-540-75203-5_2 |
1 |
|
| 2008 |
Zhang AS, Canonne-Hergaux F, Gruenheid S, Gros P, Ponka P. Use of Nramp2-transfected Chinese hamster ovary cells and reticulocytes from mk/mk mice to study iron transport mechanisms. Experimental Hematology. 36: 1227-35. PMID 18722041 DOI: 10.1016/j.exphem.2008.04.014 |
1 |
|
| 2008 |
Carrier I, Gros P. Investigating the role of the invariant carboxylate residues E552 and E1197 in the catalytic activity of Abcb1a (mouse Mdr3). The Febs Journal. 275: 3312-24. PMID 18489584 DOI: 10.1111/j.1742-4658.2008.06479.x |
1 |
|
| 2008 |
Patel SN, Berghout J, Lovegrove FE, Ayi K, Conroy A, Serghides L, Min-oo G, Gowda DC, Sarma JV, Rittirsch D, Ward PA, Liles WC, Gros P, Kain KC. C5 deficiency and C5a or C5aR blockade protects against cerebral malaria. The Journal of Experimental Medicine. 205: 1133-43. PMID 18426986 DOI: 10.1084/jem.20072248 |
1 |
|
| 2008 |
Ayi K, Min-Oo G, Serghides L, Crockett M, Kirby-Allen M, Quirt I, Gros P, Kain KC. Pyruvate kinase deficiency and malaria. The New England Journal of Medicine. 358: 1805-10. PMID 18420493 DOI: 10.1056/NEJMoa072464 |
1 |
|
| 2008 |
Valdez Y, Diehl GE, Vallance BA, Grassl GA, Guttman JA, Brown NF, Rosenberger CM, Littman DR, Gros P, Finlay BB. Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection. Cellular Microbiology. 10: 1646-61. PMID 18397382 DOI: 10.1111/j.1462-5822.2008.01155.x |
1 |
|
| 2008 |
Cai J, Damaraju VL, Groulx N, Mowles D, Peng Y, Robins MJ, Cass CE, Gros P. Two distinct molecular mechanisms underlying cytarabine resistance in human leukemic cells. Cancer Research. 68: 2349-57. PMID 18381442 DOI: 10.1158/0008-5472.CAN-07-5528 |
1 |
|
| 2008 |
Torban E, Patenaude AM, Leclerc S, Rakowiecki S, Gauthier S, Andelfinger G, Epstein DJ, Gros P. Genetic interaction between members of the Vangl family causes neural tube defects in mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 3449-54. PMID 18296642 DOI: 10.1073/pnas.0712126105 |
1 |
|
| 2008 |
Marquis JF, Nantel A, LaCourse R, Ryan L, North RJ, Gros P. Fibrotic response as a distinguishing feature of resistance and susceptibility to pulmonary infection with Mycobacterium tuberculosis in mice. Infection and Immunity. 76: 78-88. PMID 17938213 DOI: 10.1128/IAI.00369-07 |
1 |
|
| 2007 |
Roy MF, Riendeau N, Bédard C, Hélie P, Min-Oo G, Turcotte K, Gros P, Canonne-Hergaux F, Malo D. Pyruvate kinase deficiency confers susceptibility to Salmonella typhimurium infection in mice. The Journal of Experimental Medicine. 204: 2949-61. PMID 17998386 DOI: 10.1084/jem.20062606 |
1 |
|
| 2007 |
Turcotte K, Gauthier S, Malo D, Tam M, Stevenson MM, Gros P. Icsbp1/IRF-8 is required for innate and adaptive immune responses against intracellular pathogens. Journal of Immunology (Baltimore, Md. : 1950). 179: 2467-76. PMID 17675508 |
1 |
|
| 2007 |
Min-Oo G, Stevenson MM, Fortin A, Gros P. Genetic control of host-pathogen interactions in mice. Novartis Foundation Symposium. 281: 156-65; discussion 1. PMID 17534072 |
1 |
|
| 2007 |
Fortin A, Diez E, Henderson JE, Mogil JS, Gros P, Skamene E. The AcB/BcA recombinant congenic strains of mice: strategies for phenotype dissection, mapping and cloning of quantitative trait genes. Novartis Foundation Symposium. 281: 141-53; discussion 1. PMID 17534071 |
1 |
|
| 2007 |
Fortin A, Abel L, Casanova JL, Gros P. Host genetics of mycobacterial diseases in mice and men: forward genetic studies of BCG-osis and tuberculosis. Annual Review of Genomics and Human Genetics. 8: 163-92. PMID 17492906 DOI: 10.1146/annurev.genom.8.080706.092315 |
0.6 |
|
| 2007 |
Min-Oo G, Tam M, Stevenson MM, Gros P. Pyruvate kinase deficiency: correlation between enzyme activity, extent of hemolytic anemia and protection against malaria in independent mouse mutants. Blood Cells, Molecules & Diseases. 39: 63-9. PMID 17466543 DOI: 10.1016/j.bcmd.2007.03.003 |
1 |
|
| 2007 |
Kibar Z, Torban E, McDearmid JR, Reynolds A, Berghout J, Mathieu M, Kirillova I, De Marco P, Merello E, Hayes JM, Wallingford JB, Drapeau P, Capra V, Gros P. Mutations in VANGL1 associated with neural-tube defects. The New England Journal of Medicine. 356: 1432-7. PMID 17409324 DOI: 10.1056/NEJMoa060651 |
1 |
|
| 2007 |
Apuzzo S, Gros P. Cooperative interactions between the two DNA binding domains of Pax3: helix 2 of the paired domain is in the proximity of the amino terminus of the homeodomain. Biochemistry. 46: 2984-93. PMID 17323927 DOI: 10.1021/bi062107q |
1 |
|
| 2007 |
Min-Oo G, Fortin A, Pitari G, Tam M, Stevenson MM, Gros P. Complex genetic control of susceptibility to malaria: positional cloning of the Char9 locus. The Journal of Experimental Medicine. 204: 511-24. PMID 17312006 DOI: 10.1084/jem.20061252 |
1 |
|
| 2007 |
Marquis JF, Gros P. Intracellular Leishmania: your iron or mine? Trends in Microbiology. 15: 93-95. PMID 17257847 DOI: 10.1016/j.tim.2007.01.001 |
1 |
|
| 2007 |
Carrier I, Urbatsch IL, Senior AE, Gros P. Mutational analysis of conserved aromatic residues in the A-loop of the ABC transporter ABCB1A (mouse Mdr3). Febs Letters. 581: 301-8. PMID 17214987 DOI: 10.1016/j.febslet.2006.12.030 |
1 |
|
| 2006 |
Belley A, Callejo M, Arhin F, Dehbi M, Fadhil I, Liu J, McKay G, Srikumar R, Bauda P, Bergeron D, Ha N, Dubow M, Gros P, Pelletier J, Moeck G. Competition of bacteriophage polypeptides with native replicase proteins for binding to the DNA sliding clamp reveals a novel mechanism for DNA replication arrest in Staphylococcus aureus. Molecular Microbiology. 62: 1132-43. PMID 17010157 DOI: 10.1111/j.1365-2958.2006.05427.x |
1 |
|
| 2006 |
Shi L, Adkins JN, Coleman JR, Schepmoes AA, Dohnkova A, Mottaz HM, Norbeck AD, Purvine SO, Manes NP, Smallwood HS, Wang H, Forbes J, Gros P, Uzzau S, Rodland KD, et al. Proteomic analysis of Salmonella enterica serovar typhimurium isolated from RAW 264.7 macrophages: identification of a novel protein that contributes to the replication of serovar typhimurium inside macrophages. The Journal of Biological Chemistry. 281: 29131-40. PMID 16893888 DOI: 10.1074/jbc.M604640200 |
1 |
|
| 2006 |
Mullick A, Leon Z, Min-Oo G, Berghout J, Lo R, Daniels E, Gros P. Cardiac failure in C5-deficient A/J mice after Candida albicans infection. Infection and Immunity. 74: 4439-51. PMID 16861630 DOI: 10.1128/IAI.00159-06 |
0.6 |
|
| 2006 |
Arhin F, Bélanger O, Ciblat S, Dehbi M, Delorme D, Dietrich E, Dixit D, Lafontaine Y, Lehoux D, Liu J, McKay GA, Moeck G, Reddy R, Rose Y, Srikumar R, ... ... Gros P, et al. A new class of small molecule RNA polymerase inhibitors with activity against rifampicin-resistant Staphylococcus aureus. Bioorganic & Medicinal Chemistry. 14: 5812-32. PMID 16759869 DOI: 10.1016/j.bmc.2006.05.035 |
1 |
|
| 2006 |
Apuzzo S, Gros P. The paired domain of Pax3 contains a putative homeodomain interaction pocket defined by cysteine scanning mutagenesis. Biochemistry. 45: 7154-61. PMID 16752906 DOI: 10.1021/bi060009z |
1 |
|
| 2006 |
Tuite A, Gros P. The impact of genomics on the analysis of host resistance to infectious disease Microbes and Infection. 8: 1647-1653. PMID 16697229 DOI: 10.1016/j.micinf.2005.11.016 |
1 |
|
| 2006 |
Lam-Yuk-Tseung S, Gros P. Distinct targeting and recycling properties of two isoforms of the iron transporter DMT1 (NRAMP2, Slc11A2) Biochemistry. 45: 2294-2301. PMID 16475818 DOI: 10.1021/bi052307m |
1 |
|
| 2006 |
Kwan T, Liu J, Dubow M, Gros P, Pelletier J. Comparative genomic analysis of 18 Pseudomonas aeruginosa bacteriophages. Journal of Bacteriology. 188: 1184-7. PMID 16428425 DOI: 10.1128/JB.188.3.1184-1187.2006 |
0.88 |
|
| 2005 |
Min-Oo G, Gros P. Erythrocyte variants and the nature of their malaria protective effect Cellular Microbiology. 7: 753-763. PMID 15888079 DOI: 10.1111/j.1462-5822.2005.00524.x |
1 |
|
| 2005 |
Jabado N, Gros P. Tuberculosis: The genetics of vulnerability Nature. 434: 709-711. PMID 15815612 DOI: 10.1038/434709a |
1 |
|
| 2005 |
Kwan T, Liu J, DuBow M, Gros P, Pelletier J. The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages. Proceedings of the National Academy of Sciences of the United States of America. 102: 5174-9. PMID 15788529 DOI: 10.1073/pnas.0501140102 |
0.88 |
|
| 2004 |
Tuite A, Mullick A, Gros P. Genetic analysis of innate immunity in resistance to Candida albicans Genes and Immunity. 5: 576-587. PMID 15372070 DOI: 10.1038/sj.gene.6364130 |
1 |
|
| 2004 |
Apuzzo S, Abdelhakim A, Fortin AS, Gros P. Cross-talk between the paired domain and the homeodomain of Pax3: DNA binding by each domain causes a structural change in the other domain, supporting interdependence for DNA Binding. The Journal of Biological Chemistry. 279: 33601-12. PMID 15148315 DOI: 10.1074/jbc.M402949200 |
1 |
|
| 2004 |
Min-Oo G, Fortin A, Tam MF, Gros P, Stevenson MM. Phenotypic expression of pyruvate kinase deficiency and protection against malaria in a mouse model. Genes and Immunity. 5: 168-75. PMID 15029238 DOI: 10.1038/sj.gene.6364069 |
1 |
|
| 2004 |
Liu J, Dehbi M, Moeck G, Arhin F, Bauda P, Bergeron D, Callejo M, Ferretti V, Ha N, Kwan T, McCarty J, Srikumar R, Williams D, Wu JJ, Gros P, et al. Antimicrobial drug discovery through bacteriophage genomics. Nature Biotechnology. 22: 185-91. PMID 14716317 DOI: 10.1038/nbt932 |
0.88 |
|
| 2003 |
Min-Oo G, Fortin A, Tam MF, Nantel A, Stevenson MM, Gros P. Pyruvate kinase deficiency in mice protects against malaria. Nature Genetics. 35: 357-62. PMID 14595440 DOI: 10.1038/ng1260 |
1 |
|
| 2003 |
Forbes JR, Gros P. Iron, manganese, and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane. Blood. 102: 1884-92. PMID 12750164 DOI: 10.1182/blood-2003-02-0425 |
1 |
|
| 2003 |
Lam-Yuk-Tseung S, Gros P. Genetic control of susceptibility to bacterial infections in mouse models Cellular Microbiology. 5: 299-313. PMID 12713489 DOI: 10.1046/j.1462-5822.2003.00276.x |
1 |
|
| 2003 |
Cai J, Gros P. Overexpression, purification, and functional characterization of ATP-binding cassette transporters in the yeast, Pichia pastoris Biochimica Et Biophysica Acta - Biomembranes. 1610: 63-76. PMID 12586381 DOI: 10.1016/S0005-2736(02)00718-6 |
1 |
|
| 2002 |
Su Z, Fortin A, Gros P, Stevenson MM. Opsonin-independent phagocytosis: an effector mechanism against acute blood-stage Plasmodium chabaudi AS infection. The Journal of Infectious Diseases. 186: 1321-9. PMID 12402202 DOI: 10.1086/344576 |
1 |
|
| 2002 |
Apuzzo S, Gros P. Site-specific modification of single cysteine Pax 3 mutants reveals reciprocal regulation of DNA binding activity of the paired and homeo domain Biochemistry. 41: 12076-12085. PMID 12356307 DOI: 10.1021/bi0260583 |
1 |
|
| 2002 |
Fortin A, Stevenson MM, Gros P. Susceptibility to malaria as a complex trait: big pressure from a tiny creature. Human Molecular Genetics. 11: 2469-78. PMID 12351583 |
1 |
|
| 2002 |
Jabado N, Canonne-Hergaux F, Gruenheid S, Picard V, Gros P. Iron transporter Nramp2/DMT-1 is associated with the membrane of phagosomes in macrophages and Sertoli cells. Blood. 100: 2617-22. PMID 12239176 DOI: 10.1182/blood-2002-04-1182 |
1 |
|
| 2002 |
Canonne-Hergaux F, Gros P. Expression of the iron transporter DMT1 in kidney from normal and anemic mk mice Kidney International. 62: 147-156. PMID 12081573 DOI: 10.1046/j.1523-1755.2002.00405.x |
1 |
|
| 2002 |
Fortin A, Stevenson MM, Gros P. Complex genetic control of susceptibility to malaria in mice. Genes and Immunity. 3: 177-86. PMID 12058252 DOI: 10.1038/sj.gene.6363841 |
1 |
|
| 2002 |
Sebastiani G, Blais V, Sancho V, Vogel SN, Stevenson MM, Gros P, Lapointe JM, Rivest S, Malo D. Host immune response to Salmonella enterica serovar Typhimurium infection in mice derived from wild strains. Infection and Immunity. 70: 1997-2009. PMID 11895964 DOI: 10.1128/IAI.70.4.1997-2009.2002 |
1 |
|
| 2001 |
Fortin A, Cardon LR, Tam M, Skamene E, Stevenson MM, Gros P. Identification of a new malaria susceptibility locus (Char4) in recombinant congenic strains of mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 10793-8. PMID 11535821 DOI: 10.1073/pnas.191288998 |
1 |
|
| 2001 |
Forbes JR, Gros P. Divalent-metal transport by NRAMP proteins at the interface of host-pathogen interactions. Trends in Microbiology. 9: 397-403. PMID 11514223 DOI: 10.1016/S0966-842X(01)02098-4 |
1 |
|
| 2001 |
Fortin A, Diez E, Rochefort D, Laroche L, Malo D, Rouleau GA, Gros P, Skamene E. Recombinant congenic strains derived from A/J and C57BL/6J: a tool for genetic dissection of complex traits. Genomics. 74: 21-35. PMID 11374899 DOI: 10.1006/geno.2001.6528 |
1 |
|
| 2000 |
Mitsos LM, Cardon LR, Fortin A, Ryan L, LaCourse R, North RJ, Gros P. Genetic control of susceptibility to infection with Mycobacterium tuberculosis in mice. Genes and Immunity. 1: 467-77. PMID 11197687 DOI: 10.1038/sj.gene.6363712 |
0.6 |
|
| 2000 |
Fortin A, Penman M, Stevenson MM, Krieger M, Gros P. Identification and characterization of naturally occurring variants of the macrophage scavenger receptor (SR-A). Mammalian Genome : Official Journal of the International Mammalian Genome Society. 11: 779-85. PMID 10967138 DOI: 10.1007/s003350010131 |
1 |
|
| 2000 |
Kwan T, Loughrey H, Brault M, Gruenheid S, Urbatsch IL, Senior AE, Gros P. Functional analysis of a tryptophan-less P-glycoprotein: a tool for tryptophan insertion and fluorescence spectroscopy. Molecular Pharmacology. 58: 37-47. PMID 10860925 |
1 |
|
| 2000 |
Depatie C, Lee SH, Stafford A, Avner P, Belouchi A, Gros P, Vidal SM. Sequence-ready BAC contig, physical, and transcriptional map of a 2-Mb region overlapping the mouse chromosome 6 host-resistance locus Cmv1. Genomics. 66: 161-74. PMID 10860661 DOI: 10.1006/geno.2000.6186 |
1 |
|
| 2000 |
Julien M, Gros P. Nucleotide-induced conformational changes in P-glycoprotein and in nucleotide binding site mutants monitored by trypsin sensitivity Biochemistry. 39: 4559-4568. PMID 10758006 DOI: 10.1021/bi992744z |
1 |
|
| 2000 |
Sebastiani G, Leveque G, Larivière L, Laroche L, Skamene E, Gros P, Malo D. Cloning and characterization of the murine toll-like receptor 5 (Tlr5) gene: sequence and mRNA expression studies in Salmonella-susceptible MOLF/Ei mice. Genomics. 64: 230-40. PMID 10756091 DOI: 10.1006/geno.2000.6115 |
1 |
|
| 2000 |
Gruenheid S, Gros P. Genetic susceptibility to intracellular infections: Nramp1, macrophage function and divalent cations transport. Current Opinion in Microbiology. 3: 43-8. PMID 10679418 DOI: 10.1016/S1369-5274(99)00049-1 |
1 |
|
| 1999 |
Canonne-Hergaux F, Gruenheid S, Govoni G, Gros P. The Nramp1 protein and its role in resistance to infection and macrophage function. Proceedings of the Association of American Physicians. 111: 283-9. PMID 10417735 DOI: 10.1046/j.1525-1381.1999.99236.x |
1 |
|
| 1999 |
Canonne-Hergaux F, Gruenheid S, Ponka P, Gros P. Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron. Blood. 93: 4406-17. PMID 10361139 |
1 |
|
| 1999 |
Gruenheid S, Canonne-Hergaux F, Gauthier S, Hackam DJ, Grinstein S, Gros P. The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes. The Journal of Experimental Medicine. 189: 831-41. PMID 10049947 DOI: 10.1084/jem.189.5.831 |
1 |
|
| 1999 |
Gruenheid S, Skamene E, Gros P. Nramp1. A novel macrophage protein with a key function in resistance to intracellular pathogens Advances in Cellular and Molecular Biology of Membranes and Organelles. 5: 345-362. DOI: 10.1016/S1874-5172(99)80039-X |
1 |
|
| 1998 |
Gros P, Beaudet L, Urbatsch IL. Yeast as an expression system for the study of P-glycoprotein and other ABC transporters Acta Physiologica Scandinavica, Supplement. 163: 219-225. PMID 9789564 |
1 |
|
| 1998 |
Fortin AS, Underhill DA, Gros P. Helix 2 of the paired domain plays a key role in the regulation of DNA-binding by the Pax-3 homeodomain. Nucleic Acids Research. 26: 4574-81. PMID 9753723 DOI: 10.1093/nar/26.20.4574 |
1 |
|
| 1998 |
Senior AE, Gros P, Urbatsch IL. Residues in P-glycoprotein catalytic sites that react with the inhibitor 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole Archives of Biochemistry and Biophysics. 357: 121-125. PMID 9721190 DOI: 10.1006/abbi.1998.0778 |
1 |
|
| 1998 |
Govoni G, Gros P. Macrophage NRAMP1 and its role in resistance to microbial infections Inflammation Research. 47: 277-284. PMID 9719491 DOI: 10.1007/s000110050330 |
1 |
|
| 1998 |
Beaudet L, Gros P. Mutational analysis of P-glycoprotein in yeast Saccharomyces cerevisiae Methods in Enzymology. 292: 414-427. PMID 9711571 DOI: 10.1016/S0076-6879(98)92032-8 |
1 |
|
| 1998 |
Beaudet L, Urbatsch IL, Gros P. High-level expression of mouse Mdr3 P-glycoprotein in yeast Pichia pastoris and characterization of ATPase activity Methods in Enzymology. 292: 397-413. PMID 9711570 DOI: 10.1016/S0076-6879(98)92031-6 |
1 |
|
| 1998 |
Hackam DJ, Rotstein OD, Zhang W, Gruenheid S, Gros P, Grinstein S. Host resistance to intracellular infection: mutation of natural resistance-associated macrophage protein 1 (Nramp1) impairs phagosomal acidification. The Journal of Experimental Medicine. 188: 351-64. PMID 9670047 DOI: 10.1084/jem.188.2.351 |
1 |
|
| 1998 |
Hazlehurst LA, Gros P, Dalton WS. Chromosome mediated gene transfer of drug resistance to mitoxantrone. Anticancer Research. 18: 1005-10. PMID 9615755 |
1 |
|
| 1998 |
Kwan T, Gros P. Mutational analysis of the P-glycoprotein first intracellular loop and flanking transmembrane domains. Biochemistry. 37: 3337-50. PMID 9521654 DOI: 10.1021/bi972680x |
1 |
|
| 1998 |
Kast C, Gros P. Epitope insertion favors a six transmembrane domain model for the carboxy-terminal portion of the multidrug resistance-associated protein Biochemistry. 37: 2305-2313. PMID 9485377 DOI: 10.1021/bi972332v |
1 |
|
| 1998 |
Sebastiani G, Olien L, Gauthier S, Skamene E, Morgan K, Gros P, Malo D. Mapping of genetic modulators of natural resistance to infection with Salmonella typhimurium in wild-derived mice. Genomics. 47: 180-6. PMID 9479490 DOI: 10.1006/geno.1997.5116 |
1 |
|
| 1997 |
Fortin A, Belouchi A, Tam MF, Cardon L, Skamene E, Stevenson MM, Gros P. Genetic control of blood parasitaemia in mouse malaria maps to chromosome 8. Nature Genetics. 17: 382-3. PMID 9398835 DOI: 10.1038/ng1297-382 |
1 |
|
| 1997 |
Pinner E, Gruenheid S, Raymond M, Gros P. Functional complementation of the yeast divalent cation transporter family SMF by NRAMP2, a member of the mammalian natural resistance-associated macrophage protein family. The Journal of Biological Chemistry. 272: 28933-8. PMID 9360964 DOI: 10.1074/jbc.272.46.28933 |
1 |
|
| 1997 |
Vogan KJ, Gros P. The C-terminal subdomain makes an important contribution to the DNA binding activity of the Pax-3 paired domain Journal of Biological Chemistry. 272: 28289-28295. PMID 9353283 DOI: 10.1074/jbc.272.45.28289 |
1 |
|
| 1997 |
Fortin AS, Underhill DA, Gros P. Reciprocal effect of Waardenburg syndrome mutations on DNA binding by the Pax-3 paired domain and homeodomain. Human Molecular Genetics. 6: 1781-90. PMID 9302254 DOI: 10.1093/hmg/6.11.1781 |
1 |
|
| 1997 |
Alan Underhill D, Gros P. The paired-domain regulates DNA binding by the homeodomain within the intact Pax-3 protein Journal of Biological Chemistry. 272: 14175-14182. PMID 9162047 DOI: 10.1074/jbc.272.22.14175 |
1 |
|
| 1997 |
Belouchi A, Kwan T, Gros P. Cloning and characterization of the OsNramp family from Oryza sativa, a new family of membrane proteins possibly implicated in the transport of metal ions. Plant Molecular Biology. 33: 1085-92. PMID 9154989 DOI: 10.1023/A:1005723304911 |
1 |
|
| 1997 |
Gruenheid S, Pinner E, Desjardins M, Gros P. Natural resistance to infection with intracellular pathogens: the Nramp1 protein is recruited to the membrane of the phagosome. The Journal of Experimental Medicine. 185: 717-30. PMID 9034150 DOI: 10.1084/jem.185.4.717 |
1 |
|
| 1997 |
Depatie C, Muise E, Lepage P, Gros P, Vidal SM. High-resolution linkage map in the proximity of the host resistance locus Cmv1. Genomics. 39: 154-63. PMID 9027502 DOI: 10.1006/geno.1996.4498 |
1 |
|
| 1997 |
Cellier M, Gros P. The NRAMP1 gene: Resistance to intracellular infections and antimicrobial activity of phagocytes Medecine/Sciences. 13: 501-508. |
1 |
|
| 1996 |
Vogan KJ, Underhill DA, Gros P. An alternative splicing event in the Pax-3 paired domain identifies the linker region as a key determinant of paired domain DNA-binding activity Molecular and Cellular Biology. 16: 6677-6686. PMID 8943322 |
1 |
|
| 1996 |
Cellier K, Belouchi A, Gros P. Resistance to intracellular infections: Comparative genomic analysis of Nramp Trends in Genetics. 12: 201-204. PMID 8928221 DOI: 10.1016/0168-9525(96)30042-5 |
1 |
|
| 1996 |
Qureshi ST, Larivière L, Sebastiani G, Clermont S, Skamene E, Gros P, Malo D. A high-resolution map in the chromosomal region surrounding the Lps locus. Genomics. 31: 283-94. PMID 8838309 DOI: 10.1006/geno.1996.0050 |
1 |
|
| 1996 |
Jones JM, Ranscht B, Berglund EO, Gruenheid S, Gros P, Meisler MH. Close linkage of three neuronal genes on distal mouse chromosome 15. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 7: 696-7. PMID 8703126 |
1 |
|
| 1996 |
Hanna M, Brault M, Kwan T, Kast C, Gros P. Mutagenesis of transmembrane domain 11 of P-glycoprotein by alanine scanning. Biochemistry. 35: 3625-35. PMID 8639515 DOI: 10.1021/bi951333p |
1 |
|
| 1996 |
Gros P, Hanna M. Chapter 7 The P-glycoprotein family and multidrug resistance: An overview Handbook of Biological Physics. 2: 137-163. DOI: 10.1016/S1383-8121(96)80048-0 |
1 |
|
| 1995 |
Belouchi A, Cellier M, Kwan T, Saini HS, Leroux G, Gros P. The macrophage-specific membrane protein Nramp controlling natural resistance to infections in mice has homologues expressed in the root system of plants. Plant Molecular Biology. 29: 1181-96. PMID 8616217 DOI: 10.1007/BF00020461 |
1 |
|
| 1995 |
Gruenheid S, Cellier M, Vidal S, Gros P. Identification and characterization of a second mouse Nramp gene. Genomics. 25: 514-25. PMID 7789986 DOI: 10.1016/0888-7543(95)80053-O |
1 |
|
| 1995 |
Shustik C, Dalton W, Gros P. P-glycoprotein-mediated multidrug resistance in tumor cells: biochemistry, clinical relevance and modulation. Molecular Aspects of Medicine. 16: 1-78. PMID 7783568 DOI: 10.1016/0098-2997(94)00040-A |
1 |
|
| 1995 |
Sebastiani G, Durocher D, Gros P, Nemer M, Malo D. Localization of the Catf1 transcription factor gene to mouse chromosome 19. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 6: 147-8. PMID 7767002 DOI: 10.1007/BF00303264 |
1 |
|
| 1995 |
Underhill DA, Vogan KJ, Gros P. Analysis of the mouse Splotch-delayed mutation indicates that the Pax-3 paired domain can influence homeodomain DNA-binding activity Proceedings of the National Academy of Sciences of the United States of America. 92: 3692-3696. PMID 7731966 |
1 |
|
| 1995 |
Vidal S, Tremblay ML, Govoni G, Gauthier S, Sebastiani G, Malo D, Skamene E, Olivier M, Jothy S, Gros P. The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene. The Journal of Experimental Medicine. 182: 655-66. PMID 7650477 DOI: 10.1084/jem.182.3.655 |
1 |
|
| 1995 |
Lepage P, Underhill DA, Gros P. Activation of a MMTV/mdr3 Fusion Transcript from a Cryptic Viral Promoter Is Stimulated by mdr-Derived Sequences Located in Intron I Virology. 210: 244-253. PMID 7618265 DOI: 10.1006/viro.1995.1341 |
1 |
|
| 1995 |
Beaudet L, Gros P. Functional dissection of p-glycoprotein nucleotide-binding domains in chimeric and mutant proteins: Modulation of drug resistance profiles Journal of Biological Chemistry. 270: 17159-17170. PMID 7615512 DOI: 10.1074/jbc.270.29.17159 |
1 |
|
| 1995 |
Mullick A, Trasler D, Gros P. High-resolution linkage map in the vicinity of the Lp locus Genomics. 26: 479-488. PMID 7607671 DOI: 10.1016/0888-7543(95)80166-J |
1 |
|
| 1995 |
Ruetz S, Gros P. Enhancement of Mdr2-mediated phosphatidylcholine translocation by the bile salt taurocholate: Implications for hepatic bile formation Journal of Biological Chemistry. 270: 25388-25395. PMID 7592705 |
1 |
|
| 1995 |
Vidal S, Gros P, Skamene E. Natural resistance to infection with intracellular parasites: Molecular genetics identifies Nramp1 as the Bcg/Ity/Lsh locus Journal of Leukocyte Biology. 58: 382-390. PMID 7561513 |
1 |
|
| 1995 |
Cellier M, Privé G, Belouchi A, Kwan T, Rodrigues V, Chia W, Gros P. Nramp defines a family of membrane proteins Proceedings of the National Academy of Sciences of the United States of America. 92: 10089-10093. PMID 7479731 DOI: 10.1073/pnas.92.22.10089 |
1 |
|
| 1995 |
Gros P. Human (MDR1) and mouse (mdr1,mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators Biochemistry®. 34: 32-39. |
1 |
|
| 1995 |
Lepage P, Gros P. P glycoprotein: From multidrug resistance to lipid transport Medecine/Sciences. 11: 357-366. |
1 |
|
| 1994 |
Cellier M, Govoni G, Vidal S, Kwan T, Groulx N, Liu J, Sanchez F, Skamene E, Schurr E, Gros P. Human natural resistance-associated macrophage protein: cDNA cloning, chromosomal mapping, genomic organization, and tissue-specific expression. The Journal of Experimental Medicine. 180: 1741-52. PMID 7964458 DOI: 10.1084/jem.180.5.1741 |
1 |
|
| 1994 |
Ruetz S, Gros P. A mechanism for P-glycoprotein action in multidrug resistance: are we there yet? Trends in Pharmacological Sciences. 15: 260-263. PMID 7940990 DOI: 10.1016/0165-6147(94)90322-0 |
1 |
|
| 1994 |
Buschman E, Gros P. The Inability of the Mouse mdr2 Gene to Confer Multidrug Resistance Is Linked to Reduced Drug Binding to the Protein Cancer Research. 54: 4892-4898. PMID 7915194 |
1 |
|
| 1994 |
Ruetz S, Gros P. Phosphatidylcholine translocase: A physiological role for the mdr2 gene Cell. 77: 1071-1081. PMID 7912658 DOI: 10.1016/0092-8674(94)90446-4 |
1 |
|
| 1994 |
Ruetz S, Gros P. Functional expression of P-glycoproteins in secretory vesicles Journal of Biological Chemistry. 269: 12277-12284. PMID 7909318 |
1 |
|
| 1994 |
Buschman E, Lepage P, Gros P. P-glycoprotein homologues Cancer Treatment and Research. 73: 17-39. PMID 7536017 |
1 |
|
| 1993 |
Lepage P, Nepveu A, Raymond M, Gros P. Transcriptional Activation of the Mouse mdr3 Gene Coincides with the Appearance of Novel Transcription Initiation Sites in Multidrug-resistant P388 Tumor Cells Cancer Research. 53: 1657-1664. PMID 8453638 |
1 |
|
| 1993 |
Lepage P, Devault A, Gros P. Activation of the mouse mdr3 gene by insertion of retroviruses in multidrug-resistant P388 tumor cells Molecular and Cellular Biology. 13: 7380-7392. PMID 8246958 |
1 |
|
| 1993 |
Bibi E, Gros P, Kaback HR. Functional expression of mouse mdr1 in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 90: 9209-9213. PMID 8105473 |
1 |
|
| 1993 |
Gros P, Buschman E. The mouse multidrug resistance gene family: Structural and functional analysis International Review of Cytology. 137: 169-197. PMID 8098020 |
1 |
|
| 1993 |
Ruetz S, Raymond M, Gros P. Functional expression of P-glycoprotein encoded by the mouse mdr3 gene in yeast cells Proceedings of the National Academy of Sciences of the United States of America. 90: 11588-11592. PMID 7903452 |
1 |
|
| 1993 |
Lepage P, Gros P. Structural and functional aspects of P-glycoproteins and related transport proteins Current Opinion in Nephrology and Hypertension. 2: 735-743. PMID 7522912 |
1 |
|
| 1993 |
Gros P, Buschman E. The multidrug resistance transport protein: Identification of functional domains Journal of General Physiology. 101: 95-117. |
1 |
|
| 1992 |
Dhir R, Gros P. Functional analysis of chimeric proteins constructed by exchanging homologous domains of two P-glycoproteins conferring distinct drug cesistance profiles Biochemistry. 31: 6103-6110. PMID 1352702 |
1 |
|
| 1991 |
Buschman E, Gros P. Functional Analysis of Chimeric Genes Obtained by Exchanging Homologous Domains of the Mouse mdr1 and mdr2 Genes Molecular and Cellular Biology. 11: 595-603. PMID 1990275 |
1 |
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| 1991 |
Shustik C, Groulx N, Gros P. Analysis of multidrug resistance (MDR-1) gene expression in chronic lymphocytic leukaemia (CLL). British Journal of Haematology. 79: 50-6. PMID 1911388 |
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| 1991 |
Schurr E, Skamene E, Gros P. Mapping of the gene coding for the muscle protein nebulin (Neb) to the proximal region of mouse chromosome 2 Cytogenetic and Genome Research. 57: 214-216. PMID 1683831 DOI: 10.1159/000133150 |
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| 1991 |
Epstein DJ, Vekemans M, Gros P. splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3 Cell. 67: 767-774. PMID 1682057 DOI: 10.1016/0092-8674(91)90071-6 |
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| 1991 |
Gros P, Shustik C. Multidrug resistance: A novel class of membrane-associated transport proteins is identified Cancer Investigation. 9: 563-569. PMID 1682020 DOI: 10.3109/07357909109018954 |
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| 1990 |
Raymond M, Gros P. Cell-specific activity of as-acting regulatory elements in the promoter of the mouse multidrug resistance gene mdrl Molecular and Cellular Biology. 10: 6036-6040. PMID 2248681 |
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| 1990 |
Dhir R, Buschman E, Gros P. Structural and functional characterization of the mouse multidrug resistance gene family Bulletin Du Cancer. 77: 1125-1129. PMID 1980424 |
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| 1990 |
Devault A, Gros P. Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities Molecular and Cellular Biology. 10: 1652-1663. PMID 1969610 |
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| 1989 |
Hammond JR, Johnstone RM, Gros P. Enhanced efflux of [3H]vinblastine from Chinese hamster ovary cells transfected with a full-length complementary DNA clone for the mdr1 gene. Cancer Research. 49: 3867-71. PMID 2736530 |
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| 1989 |
Gros P, Malo D. A reverse genetics approach to Bcg/Ity/Lsh gene cloning Research in Immunology. 140: 774-777. PMID 2696049 DOI: 10.1016/0923-2494(89)90031-X |
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| 1989 |
Azzaria M, Schurr E, Gros P. Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance Molecular and Cellular Biology. 9: 5289-5297. PMID 2573836 |
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| 1988 |
Croop JM, Gros P, Housman DE. Genetics of multidrug resistance. The Journal of Clinical Investigation. 81: 1303-9. PMID 3284909 DOI: 10.1172/JCI113455 |
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| 1988 |
Lemontt JF, Azzaria M, Gros P. Increased mdr Gene Expression and Decreased Drug Accumulation in Multidrug-resistant Human Melanoma Cells Cancer Research. 48: 6348-6353. PMID 3180053 |
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| 1986 |
Gros P, Croop J, Housman D. Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins. Cell. 47: 371-80. PMID 3768958 DOI: 10.1016/0092-8674(86)90594-5 |
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| 1984 |
Heinrich G, Gros P, Habener JF. Glucagon gene sequence. Four of six exons encode separate functional domains of rat pre-proglucagon. The Journal of Biological Chemistry. 259: 14082-7. PMID 6094539 |
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| 1983 |
Gros P, Skamene E, Forget A. Cellular mechanisms of genetically controlled host resistance to Mycobacterium bovis (BCG) Journal of Immunology. 131: 1966-1972. PMID 6311901 |
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| 1983 |
Skamene E, Gros P. Role of macrophages in resistance against infectious diseases Clinics in Immunology and Allergy. 3: 539-560. |
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| 1981 |
Gros P, Skamene E, Forget A. Genetic control of natural resistance to Mycobacterium bovis (BCG) in mice Journal of Immunology. 127: 2417-2421. PMID 6795274 |
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