Philippe Gros - Publications

McGill University, Montreal, QC, Canada 
Immunology, Microbiology Biology

194 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Langlais D, Cencic R, Moradin N, Kennedy JM, Ayi K, Brown LE, Crandall I, Tarry MJ, Schmeing M, Kain KC, Porco JA, Pelletier J, Gros P. Rocaglates as dual-targeting agents for experimental cerebral malaria. Proceedings of the National Academy of Sciences of the United States of America. PMID 29463745 DOI: 10.1073/pnas.1713000115  0.32
2017 Fodil N, Moradin N, Leung V, Olivier JF, Radovanovic I, Jeyakumar T, Flores Molina M, McFarquhar A, Cayrol R, Bozec D, Shoukry NH, Kubo M, Dimitrieva J, Louis E, Theatre E, ... ... Gros P, et al. CCDC88B is required for pathogenesis of inflammatory bowel disease. Nature Communications. 8: 932. PMID 29030607 DOI: 10.1038/s41467-017-01381-y  0.48
2017 Valanparambil RM, Tam M, Gros PP, Auger JP, Segura M, Gros P, Jardim A, Geary TG, Ozato K, Stevenson MM. IRF-8 regulates expansion of myeloid-derived suppressor cells and Foxp3+ regulatory T cells and modulates Th2 immune responses to gastrointestinal nematode infection. Plos Pathogens. 13: e1006647. PMID 28968468 DOI: 10.1371/journal.ppat.1006647  0.6
2017 Laroque A, Min-Oo G, Tam M, Ponka P, Stevenson MM, Gros P. The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria. Plos One. 12: e0177818. PMID 28542307 DOI: 10.1371/journal.pone.0177818  0.6
2016 Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, ... ... Gros P, et al. Erratum: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation. Nature Immunology. 17: 1479. PMID 27849203 DOI: 10.1038/ni1216-1479c  0.48
2016 Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, ... ... Gros P, et al. USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation. Nature Immunology. PMID 27721430 DOI: 10.1038/ni.3581  1
2016 Moradin N, Torre S, Gauthier S, Tam M, Hawari J, Vandercruyssen K, De Spiegeleer B, Fortin A, Stevenson MM, Gros P. Cysteamine broadly improves the anti-plasmodial activity of artemisinins against murine blood stage and cerebral malaria. Malaria Journal. 15: 260. PMID 27150250 DOI: 10.1186/s12936-016-1317-3  1
2015 van Bruggen R, Gualtieri C, Iliescu A, Louicharoen Cheepsunthorn C, Mungkalasut P, Trape JF, Modiano D, Sodiomon Sirima B, Singhasivanon P, Lathrop M, Sakuntabhai A, Bureau JF, Gros P. Modulation of Malaria Phenotypes by Pyruvate Kinase (PKLR) Variants in a Thai Population. Plos One. 10: e0144555. PMID 26658699 DOI: 10.1371/journal.pone.0144555  1
2015 Van Der Kraak L, Gros P, Beauchemin N. Colitis-associated colon cancer: Is it in your genes? World Journal of Gastroenterology. 21: 11688-99. PMID 26556996 DOI: 10.3748/wjg.v21.i41.11688  1
2015 Leung V, Iliescu A, Jolicoeur C, Gravel M, Apuzzo S, Torban E, Cayouette M, Gros P. The planar cell polarity protein Vangl2 is required for retinal axon guidance. Developmental Neurobiology. PMID 25990804 DOI: 10.1002/dneu.22305  1
2015 Seo JH, Zilber Y, Babayeva S, Liu J, Kyriakopoulos P, De Marco P, Merello E, Capra V, Gros P, Torban E. Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans. Human Molecular Genetics. 24: 3893. PMID 25954026 DOI: 10.1093/hmg/ddv131  0.32
2015 Belle JI, Langlais D, Petrov JC, Pardo M, Jones RG, Gros P, Nijnik A. p53 mediates loss of hematopoietic stem cell function and lymphopenia in Mysm1 deficiency. Blood. 125: 2344-8. PMID 25710881 DOI: 10.1182/blood-2014-05-574111  1
2015 Zhang X, Bogunovic D, Payelle-Brogard B, Francois-Newton V, Speer SD, Yuan C, Volpi S, Li Z, Sanal O, Mansouri D, Tezcan I, Rice GI, Chen C, Mansouri N, Mahdaviani SA, ... ... Gros P, et al. Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation. Nature. 517: 89-93. PMID 25307056 DOI: 10.1038/nature13801  1
2015 Rocque BL, Babayeva S, Li J, Leung V, Nezvitsky L, Cybulsky AV, Gros P, Torban E. Deficiency of the planar cell polarity protein Vangl2 in podocytes affects glomerular morphogenesis and increases susceptibility to injury. Journal of the American Society of Nephrology : Jasn. 26: 576-86. PMID 25145929 DOI: 10.1681/ASN.2014040340  1
2014 Fodil N, Langlais D, Moussa P, Boivin GA, Di Pietrantonio T, Radovanovic I, Dumaine A, Blanchette M, Schurr E, Gros P, Vidal SM. Specific dysregulation of IFNγ production by natural killer cells confers susceptibility to viral infection. Plos Pathogens. 10: e1004511. PMID 25473962 DOI: 10.1371/journal.ppat.1004511  1
2014 Kennedy JM, Fodil N, Torre S, Bongfen SE, Olivier JF, Leung V, Langlais D, Meunier C, Berghout J, Langat P, Schwartzentruber J, Majewski J, Lathrop M, Vidal SM, Gros P. CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation. The Journal of Experimental Medicine. 211: 2519-35. PMID 25403443 DOI: 10.1084/jem.20140455  1
2014 Caignard G, Eva MM, van Bruggen R, Eveleigh R, Bourque G, Malo D, Gros P, Vidal SM. Mouse ENU Mutagenesis to Understand Immunity to Infection: Methods, Selected Examples, and Perspectives. Genes. 5: 887-925. PMID 25268389 DOI: 10.3390/genes5040887  1
2014 Salem S, Langlais D, Lefebvre F, Bourque G, Bigley V, Haniffa M, Casanova JL, Burk D, Berghuis A, Butler KM, Leahy TR, Hambleton S, Gros P. Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8(K108E) mutation. Blood. 124: 1894-904. PMID 25122610 DOI: 10.1182/blood-2014-04-570879  1
2014 Iliescu A, Gravel M, Horth C, Gros P. Independent mutations at Arg181 and Arg274 of Vangl proteins that are associated with neural tube defects in humans decrease protein stability and impair membrane targeting. Biochemistry. 53: 5356-64. PMID 25068569 DOI: 10.1021/bi500400g  1
2014 Gros P, Belkaid Y. Editorial overview: Host pathogens. Current Opinion in Immunology. 29: iv-vi. PMID 25027097 DOI: 10.1016/j.coi.2014.06.008  1
2014 Radovanovic I, Leung V, Iliescu A, Bongfen SE, Mullick A, Langlais D, Gros P. Genetic control of susceptibility to Candida albicans in SM/J mice. Journal of Immunology (Baltimore, Md. : 1950). 193: 1290-300. PMID 24973457 DOI: 10.4049/jimmunol.1400783  1
2014 Salem S, Gao C, Li A, Wang H, Nguyen-Yamamoto L, Goltzman D, Henderson JE, Gros P. A novel role for interferon regulatory factor 1 (IRF1) in regulation of bone metabolism. Journal of Cellular and Molecular Medicine. 18: 1588-98. PMID 24954358 DOI: 10.1111/jcmm.12327  1
2014 Dauphinee SM, Richer E, Eva MM, McIntosh F, Paquet M, Dangoor D, Burkart C, Zhang DE, Gruenheid S, Gros P, Behr M, Malo D. Contribution of increased ISG15, ISGylation and deregulated type I IFN signaling in Usp18 mutant mice during the course of bacterial infections. Genes and Immunity. 15: 282-92. PMID 24807690 DOI: 10.1038/gene.2014.17  1
2014 Meadows DN, Pyzik M, Wu Q, Torre S, Gros P, Vidal SM, Rozen R. Increased resistance to malaria in mice with methylenetetrahydrofolate reductase (Mthfr) deficiency suggests a mechanism for selection of the MTHFR 677C>T (c.665C>T) variant. Human Mutation. 35: 594-600. PMID 24616178 DOI: 10.1002/humu.22533  1
2014 Iliescu A, Gros P. The intracellular carboxyl terminal domain of Vangl proteins contains plasma membrane targeting signals. Protein Science : a Publication of the Protein Society. 23: 337-43. PMID 24452931 DOI: 10.1002/pro.2432  1
2013 Byun M, Ma CS, Akçay A, Pedergnana V, Palendira U, Myoung J, Avery DT, Liu Y, Abhyankar A, Lorenzo L, Schmidt M, Lim HK, Cassar O, Migaud M, Rozenberg F, ... ... Gros P, et al. Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood. The Journal of Experimental Medicine. 210: 1743-59. PMID 23897980 DOI: 10.1084/jem.20130592  1
2013 Berghout J, Langlais D, Radovanovic I, Tam M, MacMicking JD, Stevenson MM, Gros P. Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria. Plos Pathogens. 9: e1003491. PMID 23853600 DOI: 10.1371/journal.ppat.1003491  1
2013 Meunier C, Van Der Kraak L, Turbide C, Groulx N, Labouba I, Cingolani P, Blanchette M, Yeretssian G, Mes-Masson AM, Saleh M, Beauchemin N, Gros P. Positional mapping and candidate gene analysis of the mouse Ccs3 locus that regulates differential susceptibility to carcinogen-induced colorectal cancer. Plos One. 8: e58733. PMID 23516545 DOI: 10.1371/journal.pone.0058733  1
2013 Salem S, Gros P. Genetic determinants of susceptibility to Mycobacterial infections: IRF8, a new kid on the block. Advances in Experimental Medicine and Biology. 783: 45-80. PMID 23468103 DOI: 10.1007/978-1-4614-6111-1_3  1
2012 Torban E, Iliescu A, Gros P. An expanding role of Vangl proteins in embryonic development. Current Topics in Developmental Biology. 101: 237-61. PMID 23140632 DOI: 10.1016/B978-0-12-394592-1.00005-3  1
2012 Idaghdour Y, Quinlan J, Goulet JP, Berghout J, Gbeha E, Bruat V, de Malliard T, Grenier JC, Gomez S, Gros P, Rahimy MC, Sanni A, Awadalla P. Evidence for additive and interaction effects of host genotype and infection in malaria. Proceedings of the National Academy of Sciences of the United States of America. 109: 16786-93. PMID 22949651 DOI: 10.1073/pnas.1204945109  1
2012 Bogunovic D, Byun M, Durfee LA, Abhyankar A, Sanal O, Mansouri D, Salem S, Radovanovic I, Grant AV, Adimi P, Mansouri N, Okada S, Bryant VL, Kong XF, Kreins A, ... ... Gros P, et al. Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency. Science (New York, N.Y.). 337: 1684-8. PMID 22859821 DOI: 10.1126/science.1224026  1
2012 Bongfen SE, Rodrigue-Gervais IG, Berghout J, Torre S, Cingolani P, Wiltshire SA, Leiva-Torres GA, Letourneau L, Sladek R, Blanchette M, Lathrop M, Behr MA, Gruenheid S, Vidal SM, Saleh M, ... Gros P, et al. An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria. Plos One. 7: e31012. PMID 22363534 DOI: 10.1371/journal.pone.0031012  1
2011 Ramirez-Aquino R, Radovanovic I, Fortin A, Sciutto-Conde E, Fragoso-González G, Gros P, Aguilar-Delfin I. Identification of loci controlling restriction of parasite growth in experimental Taenia crassiceps cysticercosis. Plos Neglected Tropical Diseases. 5: e1435. PMID 22206032 DOI: 10.1371/journal.pntd.0001435  1
2011 Seo JH, Zilber Y, Babayeva S, Liu J, Kyriakopoulos P, De Marco P, Merello E, Capra V, Gros P, Torban E. Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans. Human Molecular Genetics. 20: 4324-33. PMID 21840926 DOI: 10.1093/hmg/ddr359  1
2011 Fortier A, Faucher SP, Diallo K, Gros P. Global cellular changes induced by Legionella pneumophila infection of bone marrow-derived macrophages. Immunobiology. 216: 1274-85. PMID 21794945 DOI: 10.1016/j.imbio.2011.06.008  1
2011 Marquis JF, Kapoustina O, Langlais D, Ruddy R, Dufour CR, Kim BH, MacMicking JD, Giguère V, Gros P. Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis. Plos Genetics. 7: e1002097. PMID 21731497 DOI: 10.1371/journal.pgen.1002097  1
2011 Meunier C, Kwan T, Turbide C, Beauchemin N, Gros P. Genetic control of susceptibility to carcinogen-induced colorectal cancer in mice: the Ccs3 and Ccs5 loci regulate different aspects of tumorigenesis. Cell Cycle (Georgetown, Tex.). 10: 1739-49. PMID 21543896  0.88
2011 Radovanovic I, Mullick A, Gros P. Genetic control of susceptibility to infection with Candida albicans in mice. Plos One. 6: e18957. PMID 21533108 DOI: 10.1371/journal.pone.0018957  1
2011 Hambleton S, Salem S, Bustamante J, Bigley V, Boisson-Dupuis S, Azevedo J, Fortin A, Haniffa M, Ceron-Gutierrez L, Bacon CM, Menon G, Trouillet C, McDonald D, Carey P, Ginhoux F, ... ... Gros P, et al. IRF8 mutations and human dendritic-cell immunodeficiency. The New England Journal of Medicine. 365: 127-38. PMID 21524210 DOI: 10.1056/NEJMoa1100066  1
2011 Min-Oo G, Gros P. Genetic analysis in mice identifies cysteamine as a novel partner for artemisinin in the treatment of malaria. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 22: 486-94. PMID 21437649 DOI: 10.1007/s00335-011-9316-8  1
2011 Guyot MC, Bosoi CM, Kharfallah F, Reynolds A, Drapeau P, Justice M, Gros P, Kibar Z. A novel hypomorphic Looptail allele at the planar cell polarity Vangl2 gene. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 839-49. PMID 21404367 DOI: 10.1002/dvdy.22577  1
2011 Iliescu A, Gravel M, Horth C, Apuzzo S, Gros P. Transmembrane topology of mammalian planar cell polarity protein Vangl1. Biochemistry. 50: 2274-82. PMID 21291170 DOI: 10.1021/bi101767a  1
2011 Iliescu A, Gravel M, Horth C, Kibar Z, Gros P. Loss of membrane targeting of Vangl proteins causes neural tube defects. Biochemistry. 50: 795-804. PMID 21142127 DOI: 10.1021/bi101286d  1
2011 Longley R, Smith C, Fortin A, Berghout J, McMorran B, Burgio G, Foote S, Gros P. Host resistance to malaria: using mouse models to explore the host response. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 22: 32-42. PMID 21116636 DOI: 10.1007/s00335-010-9302-6  1
2010 Gruenheid S, Gros P. Forward genetic dissection of innate response to infection in inbred mouse strains: selected success stories. Clinical and Experimental Immunology. 162: 393-401. PMID 21070206 DOI: 10.1111/j.1365-2249.2010.04249.x  1
2010 Min-Oo G, Fortin A, Poulin JF, Gros P. Cysteamine, the molecule used to treat cystinosis, potentiates the antimalarial efficacy of artemisinin. Antimicrobial Agents and Chemotherapy. 54: 3262-70. PMID 20479197 DOI: 10.1128/AAC.01719-09  1
2010 Murawski IJ, Maina RW, Malo D, Guay-Woodford LM, Gros P, Fujiwara M, Morgan K, Gupta IR. The C3H/HeJ inbred mouse is a model of vesico-ureteric reflux with a susceptibility locus on chromosome 12. Kidney International. 78: 269-78. PMID 20407478 DOI: 10.1038/ki.2010.110  1
2010 Stevenson MM, Gros P, Olivier M, Fortin A, Serghides L. Cerebral malaria: human versus mouse studies. Trends in Parasitology. 26: 274-5. PMID 20382077 DOI: 10.1016/  1
2010 Gravel M, Iliescu A, Horth C, Apuzzo S, Gros P. Molecular and cellular mechanisms underlying neural tube defects in the loop-tail mutant mouse Biochemistry. 49: 3445-3455. PMID 20329788 DOI: 10.1021/bi902180m  1
2010 Min-Oo G, Ayi K, Bongfen SE, Tam M, Radovanovic I, Gauthier S, Santiago H, Rothfuchs AG, Roffê E, Sher A, Mullick A, Fortin A, Stevenson MM, Kain KC, Gros P. Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium. Experimental Parasitology. 125: 315-24. PMID 20219464 DOI: 10.1016/j.exppara.2010.02.009  1
2010 Behr M, Schurr E, Gros P. TB: screening for responses to a vile visitor. Cell. 140: 615-8. PMID 20211131 DOI: 10.1016/j.cell.2010.02.030  0.32
2010 Reynolds A, McDearmid JR, Lachance S, De Marco P, Merello E, Capra V, Gros P, Drapeau P, Kibar Z. VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish. Mechanisms of Development. 127: 385-92. PMID 20043994 DOI: 10.1016/j.mod.2009.12.002  1
2010 Meunier C, Cai J, Fortin A, Kwan T, Marquis JF, Turbide C, Van Der Kraak L, Jothy S, Beauchemin N, Gros P. Characterization of a major colon cancer susceptibility locus (Ccs3) on mouse chromosome 3 Oncogene. 29: 647-661. PMID 19915610 DOI: 10.1038/onc.2009.369  1
2009 Schurr E, Gros P. A common genetic fingerprint in leprosy and Crohn's disease? The New England Journal of Medicine. 361: 2666-8. PMID 20018963 DOI: 10.1056/NEJMe0910690  1
2009 Ayi K, Liles WC, Gros P, Kain KC. Adenosine triphosphate depletion of erythrocytes simulates the phenotype associated with pyruvate kinase deficiency and confers protection against Plasmodium falciparum in vitro. The Journal of Infectious Diseases. 200: 1289-99. PMID 19743919 DOI: 10.1086/605843  1
2009 Fortier A, Doiron K, Saleh M, Grinstein S, Gros P. Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4. Infection and Immunity. 77: 4794-805. PMID 19720760 DOI: 10.1128/IAI.01546-08  0.4
2009 Czachorowski M, Lam-Yuk-Tseung S, Cellier M, Gros P. Transmembrane topology of the mammalian Slc11a2 iron transporter. Biochemistry. 48: 8422-34. PMID 19621945 DOI: 10.1021/bi900606y  0.4
2009 Kibar Z, Bosoi CM, Kooistra M, Salem S, Finnell RH, De Marco P, Merello E, Bassuk AG, Capra V, Gros P. Novel mutations in VANGL1 in neural tube defects. Human Mutation. 30: E706-15. PMID 19319979 DOI: 10.1002/humu.21026  1
2009 Marquis JF, Lacourse R, Ryan L, North RJ, Gros P. Genetic and functional characterization of the mouse Trl3 locus in defense against tuberculosis. Journal of Immunology (Baltimore, Md. : 1950). 182: 3757-67. PMID 19265154 DOI: 10.4049/jimmunol.0802094  1
2009 Marquis JF, LaCourse R, Ryan L, North RJ, Gros P. Disseminated and rapidly fatal tuberculosis in mice bearing a defective allele at IFN regulatory factor 8. Journal of Immunology (Baltimore, Md. : 1950). 182: 3008-15. PMID 19234196 DOI: 10.4049/jimmunol.0800680  1
2008 Divangahi M, Mostowy S, Coulombe F, Kozak R, Guillot L, Veyrier F, Kobayashi KS, Flavell RA, Gros P, Behr MA. NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity. Journal of Immunology (Baltimore, Md. : 1950). 181: 7157-65. PMID 18981137  1
2008 Marquis JF, Gros P. Genetic analysis of resistance to infections in mice: A/J meets C57BL/6J Current Topics in Microbiology and Immunology. 321: 27-57. PMID 18727486 DOI: 10.1007/978-3-540-75203-5_2  1
2008 Zhang AS, Canonne-Hergaux F, Gruenheid S, Gros P, Ponka P. Use of Nramp2-transfected Chinese hamster ovary cells and reticulocytes from mk/mk mice to study iron transport mechanisms. Experimental Hematology. 36: 1227-35. PMID 18722041 DOI: 10.1016/j.exphem.2008.04.014  1
2008 Carrier I, Gros P. Investigating the role of the invariant carboxylate residues E552 and E1197 in the catalytic activity of Abcb1a (mouse Mdr3). The Febs Journal. 275: 3312-24. PMID 18489584 DOI: 10.1111/j.1742-4658.2008.06479.x  1
2008 Patel SN, Berghout J, Lovegrove FE, Ayi K, Conroy A, Serghides L, Min-oo G, Gowda DC, Sarma JV, Rittirsch D, Ward PA, Liles WC, Gros P, Kain KC. C5 deficiency and C5a or C5aR blockade protects against cerebral malaria. The Journal of Experimental Medicine. 205: 1133-43. PMID 18426986 DOI: 10.1084/jem.20072248  1
2008 Ayi K, Min-Oo G, Serghides L, Crockett M, Kirby-Allen M, Quirt I, Gros P, Kain KC. Pyruvate kinase deficiency and malaria. The New England Journal of Medicine. 358: 1805-10. PMID 18420493 DOI: 10.1056/NEJMoa072464  1
2008 Valdez Y, Diehl GE, Vallance BA, Grassl GA, Guttman JA, Brown NF, Rosenberger CM, Littman DR, Gros P, Finlay BB. Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection. Cellular Microbiology. 10: 1646-61. PMID 18397382 DOI: 10.1111/j.1462-5822.2008.01155.x  1
2008 Cai J, Damaraju VL, Groulx N, Mowles D, Peng Y, Robins MJ, Cass CE, Gros P. Two distinct molecular mechanisms underlying cytarabine resistance in human leukemic cells. Cancer Research. 68: 2349-57. PMID 18381442 DOI: 10.1158/0008-5472.CAN-07-5528  1
2008 Torban E, Patenaude AM, Leclerc S, Rakowiecki S, Gauthier S, Andelfinger G, Epstein DJ, Gros P. Genetic interaction between members of the Vangl family causes neural tube defects in mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 3449-54. PMID 18296642 DOI: 10.1073/pnas.0712126105  1
2008 Marquis JF, Nantel A, LaCourse R, Ryan L, North RJ, Gros P. Fibrotic response as a distinguishing feature of resistance and susceptibility to pulmonary infection with Mycobacterium tuberculosis in mice. Infection and Immunity. 76: 78-88. PMID 17938213 DOI: 10.1128/IAI.00369-07  1
2007 Roy MF, Riendeau N, Bédard C, Hélie P, Min-Oo G, Turcotte K, Gros P, Canonne-Hergaux F, Malo D. Pyruvate kinase deficiency confers susceptibility to Salmonella typhimurium infection in mice. The Journal of Experimental Medicine. 204: 2949-61. PMID 17998386 DOI: 10.1084/jem.20062606  1
2007 Turcotte K, Gauthier S, Malo D, Tam M, Stevenson MM, Gros P. Icsbp1/IRF-8 is required for innate and adaptive immune responses against intracellular pathogens. Journal of Immunology (Baltimore, Md. : 1950). 179: 2467-76. PMID 17675508  1
2007 Min-Oo G, Stevenson MM, Fortin A, Gros P. Genetic control of host-pathogen interactions in mice. Novartis Foundation Symposium. 281: 156-65; discussion 1. PMID 17534072  1
2007 Fortin A, Diez E, Henderson JE, Mogil JS, Gros P, Skamene E. The AcB/BcA recombinant congenic strains of mice: strategies for phenotype dissection, mapping and cloning of quantitative trait genes. Novartis Foundation Symposium. 281: 141-53; discussion 1. PMID 17534071  1
2007 Fortin A, Abel L, Casanova JL, Gros P. Host genetics of mycobacterial diseases in mice and men: forward genetic studies of BCG-osis and tuberculosis. Annual Review of Genomics and Human Genetics. 8: 163-92. PMID 17492906 DOI: 10.1146/annurev.genom.8.080706.092315  0.6
2007 Min-Oo G, Tam M, Stevenson MM, Gros P. Pyruvate kinase deficiency: correlation between enzyme activity, extent of hemolytic anemia and protection against malaria in independent mouse mutants. Blood Cells, Molecules & Diseases. 39: 63-9. PMID 17466543 DOI: 10.1016/j.bcmd.2007.03.003  1
2007 Kibar Z, Torban E, McDearmid JR, Reynolds A, Berghout J, Mathieu M, Kirillova I, De Marco P, Merello E, Hayes JM, Wallingford JB, Drapeau P, Capra V, Gros P. Mutations in VANGL1 associated with neural-tube defects. The New England Journal of Medicine. 356: 1432-7. PMID 17409324 DOI: 10.1056/NEJMoa060651  1
2007 Apuzzo S, Gros P. Cooperative interactions between the two DNA binding domains of Pax3: helix 2 of the paired domain is in the proximity of the amino terminus of the homeodomain. Biochemistry. 46: 2984-93. PMID 17323927 DOI: 10.1021/bi062107q  1
2007 Min-Oo G, Fortin A, Pitari G, Tam M, Stevenson MM, Gros P. Complex genetic control of susceptibility to malaria: positional cloning of the Char9 locus. The Journal of Experimental Medicine. 204: 511-24. PMID 17312006 DOI: 10.1084/jem.20061252  1
2007 Marquis JF, Gros P. Intracellular Leishmania: your iron or mine? Trends in Microbiology. 15: 93-95. PMID 17257847 DOI: 10.1016/j.tim.2007.01.001  1
2007 Carrier I, Urbatsch IL, Senior AE, Gros P. Mutational analysis of conserved aromatic residues in the A-loop of the ABC transporter ABCB1A (mouse Mdr3). Febs Letters. 581: 301-8. PMID 17214987 DOI: 10.1016/j.febslet.2006.12.030  1
2006 Belley A, Callejo M, Arhin F, Dehbi M, Fadhil I, Liu J, McKay G, Srikumar R, Bauda P, Bergeron D, Ha N, Dubow M, Gros P, Pelletier J, Moeck G. Competition of bacteriophage polypeptides with native replicase proteins for binding to the DNA sliding clamp reveals a novel mechanism for DNA replication arrest in Staphylococcus aureus. Molecular Microbiology. 62: 1132-43. PMID 17010157 DOI: 10.1111/j.1365-2958.2006.05427.x  1
2006 Shi L, Adkins JN, Coleman JR, Schepmoes AA, Dohnkova A, Mottaz HM, Norbeck AD, Purvine SO, Manes NP, Smallwood HS, Wang H, Forbes J, Gros P, Uzzau S, Rodland KD, et al. Proteomic analysis of Salmonella enterica serovar typhimurium isolated from RAW 264.7 macrophages: identification of a novel protein that contributes to the replication of serovar typhimurium inside macrophages. The Journal of Biological Chemistry. 281: 29131-40. PMID 16893888 DOI: 10.1074/jbc.M604640200  1
2006 Mullick A, Leon Z, Min-Oo G, Berghout J, Lo R, Daniels E, Gros P. Cardiac failure in C5-deficient A/J mice after Candida albicans infection. Infection and Immunity. 74: 4439-51. PMID 16861630 DOI: 10.1128/IAI.00159-06  0.6
2006 Arhin F, Bélanger O, Ciblat S, Dehbi M, Delorme D, Dietrich E, Dixit D, Lafontaine Y, Lehoux D, Liu J, McKay GA, Moeck G, Reddy R, Rose Y, Srikumar R, ... ... Gros P, et al. A new class of small molecule RNA polymerase inhibitors with activity against rifampicin-resistant Staphylococcus aureus. Bioorganic & Medicinal Chemistry. 14: 5812-32. PMID 16759869 DOI: 10.1016/j.bmc.2006.05.035  1
2006 Apuzzo S, Gros P. The paired domain of Pax3 contains a putative homeodomain interaction pocket defined by cysteine scanning mutagenesis. Biochemistry. 45: 7154-61. PMID 16752906 DOI: 10.1021/bi060009z  1
2006 Tuite A, Gros P. The impact of genomics on the analysis of host resistance to infectious disease Microbes and Infection. 8: 1647-1653. PMID 16697229 DOI: 10.1016/j.micinf.2005.11.016  1
2006 Lam-Yuk-Tseung S, Gros P. Distinct targeting and recycling properties of two isoforms of the iron transporter DMT1 (NRAMP2, Slc11A2) Biochemistry. 45: 2294-2301. PMID 16475818 DOI: 10.1021/bi052307m  1
2006 Kwan T, Liu J, Dubow M, Gros P, Pelletier J. Comparative genomic analysis of 18 Pseudomonas aeruginosa bacteriophages. Journal of Bacteriology. 188: 1184-7. PMID 16428425 DOI: 10.1128/JB.188.3.1184-1187.2006  0.88
2005 Min-Oo G, Gros P. Erythrocyte variants and the nature of their malaria protective effect Cellular Microbiology. 7: 753-763. PMID 15888079 DOI: 10.1111/j.1462-5822.2005.00524.x  1
2005 Jabado N, Gros P. Tuberculosis: The genetics of vulnerability Nature. 434: 709-711. PMID 15815612 DOI: 10.1038/434709a  1
2005 Kwan T, Liu J, DuBow M, Gros P, Pelletier J. The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages. Proceedings of the National Academy of Sciences of the United States of America. 102: 5174-9. PMID 15788529 DOI: 10.1073/pnas.0501140102  0.88
2004 Tuite A, Mullick A, Gros P. Genetic analysis of innate immunity in resistance to Candida albicans Genes and Immunity. 5: 576-587. PMID 15372070 DOI: 10.1038/sj.gene.6364130  1
2004 Apuzzo S, Abdelhakim A, Fortin AS, Gros P. Cross-talk between the paired domain and the homeodomain of Pax3: DNA binding by each domain causes a structural change in the other domain, supporting interdependence for DNA Binding. The Journal of Biological Chemistry. 279: 33601-12. PMID 15148315 DOI: 10.1074/jbc.M402949200  1
2004 Min-Oo G, Fortin A, Tam MF, Gros P, Stevenson MM. Phenotypic expression of pyruvate kinase deficiency and protection against malaria in a mouse model. Genes and Immunity. 5: 168-75. PMID 15029238 DOI: 10.1038/sj.gene.6364069  1
2004 Liu J, Dehbi M, Moeck G, Arhin F, Bauda P, Bergeron D, Callejo M, Ferretti V, Ha N, Kwan T, McCarty J, Srikumar R, Williams D, Wu JJ, Gros P, et al. Antimicrobial drug discovery through bacteriophage genomics. Nature Biotechnology. 22: 185-91. PMID 14716317 DOI: 10.1038/nbt932  0.88
2003 Min-Oo G, Fortin A, Tam MF, Nantel A, Stevenson MM, Gros P. Pyruvate kinase deficiency in mice protects against malaria. Nature Genetics. 35: 357-62. PMID 14595440 DOI: 10.1038/ng1260  1
2003 Forbes JR, Gros P. Iron, manganese, and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane. Blood. 102: 1884-92. PMID 12750164 DOI: 10.1182/blood-2003-02-0425  1
2003 Lam-Yuk-Tseung S, Gros P. Genetic control of susceptibility to bacterial infections in mouse models Cellular Microbiology. 5: 299-313. PMID 12713489 DOI: 10.1046/j.1462-5822.2003.00276.x  1
2003 Cai J, Gros P. Overexpression, purification, and functional characterization of ATP-binding cassette transporters in the yeast, Pichia pastoris Biochimica Et Biophysica Acta - Biomembranes. 1610: 63-76. PMID 12586381 DOI: 10.1016/S0005-2736(02)00718-6  1
2002 Su Z, Fortin A, Gros P, Stevenson MM. Opsonin-independent phagocytosis: an effector mechanism against acute blood-stage Plasmodium chabaudi AS infection. The Journal of Infectious Diseases. 186: 1321-9. PMID 12402202 DOI: 10.1086/344576  1
2002 Apuzzo S, Gros P. Site-specific modification of single cysteine Pax 3 mutants reveals reciprocal regulation of DNA binding activity of the paired and homeo domain Biochemistry. 41: 12076-12085. PMID 12356307 DOI: 10.1021/bi0260583  1
2002 Fortin A, Stevenson MM, Gros P. Susceptibility to malaria as a complex trait: big pressure from a tiny creature. Human Molecular Genetics. 11: 2469-78. PMID 12351583  1
2002 Jabado N, Canonne-Hergaux F, Gruenheid S, Picard V, Gros P. Iron transporter Nramp2/DMT-1 is associated with the membrane of phagosomes in macrophages and Sertoli cells. Blood. 100: 2617-22. PMID 12239176 DOI: 10.1182/blood-2002-04-1182  1
2002 Canonne-Hergaux F, Gros P. Expression of the iron transporter DMT1 in kidney from normal and anemic mk mice Kidney International. 62: 147-156. PMID 12081573 DOI: 10.1046/j.1523-1755.2002.00405.x  1
2002 Fortin A, Stevenson MM, Gros P. Complex genetic control of susceptibility to malaria in mice. Genes and Immunity. 3: 177-86. PMID 12058252 DOI: 10.1038/sj.gene.6363841  1
2002 Sebastiani G, Blais V, Sancho V, Vogel SN, Stevenson MM, Gros P, Lapointe JM, Rivest S, Malo D. Host immune response to Salmonella enterica serovar Typhimurium infection in mice derived from wild strains. Infection and Immunity. 70: 1997-2009. PMID 11895964 DOI: 10.1128/IAI.70.4.1997-2009.2002  1
2001 Fortin A, Cardon LR, Tam M, Skamene E, Stevenson MM, Gros P. Identification of a new malaria susceptibility locus (Char4) in recombinant congenic strains of mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 10793-8. PMID 11535821 DOI: 10.1073/pnas.191288998  1
2001 Forbes JR, Gros P. Divalent-metal transport by NRAMP proteins at the interface of host-pathogen interactions. Trends in Microbiology. 9: 397-403. PMID 11514223 DOI: 10.1016/S0966-842X(01)02098-4  1
2001 Fortin A, Diez E, Rochefort D, Laroche L, Malo D, Rouleau GA, Gros P, Skamene E. Recombinant congenic strains derived from A/J and C57BL/6J: a tool for genetic dissection of complex traits. Genomics. 74: 21-35. PMID 11374899 DOI: 10.1006/geno.2001.6528  1
2000 Mitsos LM, Cardon LR, Fortin A, Ryan L, LaCourse R, North RJ, Gros P. Genetic control of susceptibility to infection with Mycobacterium tuberculosis in mice. Genes and Immunity. 1: 467-77. PMID 11197687 DOI: 10.1038/sj.gene.6363712  0.6
2000 Fortin A, Penman M, Stevenson MM, Krieger M, Gros P. Identification and characterization of naturally occurring variants of the macrophage scavenger receptor (SR-A). Mammalian Genome : Official Journal of the International Mammalian Genome Society. 11: 779-85. PMID 10967138 DOI: 10.1007/s003350010131  1
2000 Kwan T, Loughrey H, Brault M, Gruenheid S, Urbatsch IL, Senior AE, Gros P. Functional analysis of a tryptophan-less P-glycoprotein: a tool for tryptophan insertion and fluorescence spectroscopy. Molecular Pharmacology. 58: 37-47. PMID 10860925  1
2000 Depatie C, Lee SH, Stafford A, Avner P, Belouchi A, Gros P, Vidal SM. Sequence-ready BAC contig, physical, and transcriptional map of a 2-Mb region overlapping the mouse chromosome 6 host-resistance locus Cmv1. Genomics. 66: 161-74. PMID 10860661 DOI: 10.1006/geno.2000.6186  1
2000 Julien M, Gros P. Nucleotide-induced conformational changes in P-glycoprotein and in nucleotide binding site mutants monitored by trypsin sensitivity Biochemistry. 39: 4559-4568. PMID 10758006 DOI: 10.1021/bi992744z  1
2000 Sebastiani G, Leveque G, Larivière L, Laroche L, Skamene E, Gros P, Malo D. Cloning and characterization of the murine toll-like receptor 5 (Tlr5) gene: sequence and mRNA expression studies in Salmonella-susceptible MOLF/Ei mice. Genomics. 64: 230-40. PMID 10756091 DOI: 10.1006/geno.2000.6115  1
2000 Gruenheid S, Gros P. Genetic susceptibility to intracellular infections: Nramp1, macrophage function and divalent cations transport. Current Opinion in Microbiology. 3: 43-8. PMID 10679418 DOI: 10.1016/S1369-5274(99)00049-1  1
1999 Canonne-Hergaux F, Gruenheid S, Govoni G, Gros P. The Nramp1 protein and its role in resistance to infection and macrophage function. Proceedings of the Association of American Physicians. 111: 283-9. PMID 10417735 DOI: 10.1046/j.1525-1381.1999.99236.x  1
1999 Canonne-Hergaux F, Gruenheid S, Ponka P, Gros P. Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron. Blood. 93: 4406-17. PMID 10361139  1
1999 Gruenheid S, Canonne-Hergaux F, Gauthier S, Hackam DJ, Grinstein S, Gros P. The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes. The Journal of Experimental Medicine. 189: 831-41. PMID 10049947 DOI: 10.1084/jem.189.5.831  1
1999 Gruenheid S, Skamene E, Gros P. Nramp1. A novel macrophage protein with a key function in resistance to intracellular pathogens Advances in Cellular and Molecular Biology of Membranes and Organelles. 5: 345-362. DOI: 10.1016/S1874-5172(99)80039-X  1
1998 Gros P, Beaudet L, Urbatsch IL. Yeast as an expression system for the study of P-glycoprotein and other ABC transporters Acta Physiologica Scandinavica, Supplement. 163: 219-225. PMID 9789564  1
1998 Fortin AS, Underhill DA, Gros P. Helix 2 of the paired domain plays a key role in the regulation of DNA-binding by the Pax-3 homeodomain. Nucleic Acids Research. 26: 4574-81. PMID 9753723 DOI: 10.1093/nar/26.20.4574  1
1998 Senior AE, Gros P, Urbatsch IL. Residues in P-glycoprotein catalytic sites that react with the inhibitor 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole Archives of Biochemistry and Biophysics. 357: 121-125. PMID 9721190 DOI: 10.1006/abbi.1998.0778  1
1998 Govoni G, Gros P. Macrophage NRAMP1 and its role in resistance to microbial infections Inflammation Research. 47: 277-284. PMID 9719491 DOI: 10.1007/s000110050330  1
1998 Beaudet L, Gros P. Mutational analysis of P-glycoprotein in yeast Saccharomyces cerevisiae Methods in Enzymology. 292: 414-427. PMID 9711571 DOI: 10.1016/S0076-6879(98)92032-8  1
1998 Beaudet L, Urbatsch IL, Gros P. High-level expression of mouse Mdr3 P-glycoprotein in yeast Pichia pastoris and characterization of ATPase activity Methods in Enzymology. 292: 397-413. PMID 9711570 DOI: 10.1016/S0076-6879(98)92031-6  1
1998 Hackam DJ, Rotstein OD, Zhang W, Gruenheid S, Gros P, Grinstein S. Host resistance to intracellular infection: mutation of natural resistance-associated macrophage protein 1 (Nramp1) impairs phagosomal acidification. The Journal of Experimental Medicine. 188: 351-64. PMID 9670047 DOI: 10.1084/jem.188.2.351  1
1998 Hazlehurst LA, Gros P, Dalton WS. Chromosome mediated gene transfer of drug resistance to mitoxantrone. Anticancer Research. 18: 1005-10. PMID 9615755  1
1998 Kwan T, Gros P. Mutational analysis of the P-glycoprotein first intracellular loop and flanking transmembrane domains. Biochemistry. 37: 3337-50. PMID 9521654 DOI: 10.1021/bi972680x  1
1998 Kast C, Gros P. Epitope insertion favors a six transmembrane domain model for the carboxy-terminal portion of the multidrug resistance-associated protein Biochemistry. 37: 2305-2313. PMID 9485377 DOI: 10.1021/bi972332v  1
1998 Sebastiani G, Olien L, Gauthier S, Skamene E, Morgan K, Gros P, Malo D. Mapping of genetic modulators of natural resistance to infection with Salmonella typhimurium in wild-derived mice. Genomics. 47: 180-6. PMID 9479490 DOI: 10.1006/geno.1997.5116  1
1997 Fortin A, Belouchi A, Tam MF, Cardon L, Skamene E, Stevenson MM, Gros P. Genetic control of blood parasitaemia in mouse malaria maps to chromosome 8. Nature Genetics. 17: 382-3. PMID 9398835 DOI: 10.1038/ng1297-382  1
1997 Pinner E, Gruenheid S, Raymond M, Gros P. Functional complementation of the yeast divalent cation transporter family SMF by NRAMP2, a member of the mammalian natural resistance-associated macrophage protein family. The Journal of Biological Chemistry. 272: 28933-8. PMID 9360964 DOI: 10.1074/jbc.272.46.28933  1
1997 Vogan KJ, Gros P. The C-terminal subdomain makes an important contribution to the DNA binding activity of the Pax-3 paired domain Journal of Biological Chemistry. 272: 28289-28295. PMID 9353283 DOI: 10.1074/jbc.272.45.28289  1
1997 Fortin AS, Underhill DA, Gros P. Reciprocal effect of Waardenburg syndrome mutations on DNA binding by the Pax-3 paired domain and homeodomain. Human Molecular Genetics. 6: 1781-90. PMID 9302254 DOI: 10.1093/hmg/6.11.1781  1
1997 Alan Underhill D, Gros P. The paired-domain regulates DNA binding by the homeodomain within the intact Pax-3 protein Journal of Biological Chemistry. 272: 14175-14182. PMID 9162047 DOI: 10.1074/jbc.272.22.14175  1
1997 Belouchi A, Kwan T, Gros P. Cloning and characterization of the OsNramp family from Oryza sativa, a new family of membrane proteins possibly implicated in the transport of metal ions. Plant Molecular Biology. 33: 1085-92. PMID 9154989 DOI: 10.1023/A:1005723304911  1
1997 Gruenheid S, Pinner E, Desjardins M, Gros P. Natural resistance to infection with intracellular pathogens: the Nramp1 protein is recruited to the membrane of the phagosome. The Journal of Experimental Medicine. 185: 717-30. PMID 9034150 DOI: 10.1084/jem.185.4.717  1
1997 Depatie C, Muise E, Lepage P, Gros P, Vidal SM. High-resolution linkage map in the proximity of the host resistance locus Cmv1. Genomics. 39: 154-63. PMID 9027502 DOI: 10.1006/geno.1996.4498  1
1997 Cellier M, Gros P. The NRAMP1 gene: Resistance to intracellular infections and antimicrobial activity of phagocytes Medecine/Sciences. 13: 501-508.  1
1996 Vogan KJ, Underhill DA, Gros P. An alternative splicing event in the Pax-3 paired domain identifies the linker region as a key determinant of paired domain DNA-binding activity Molecular and Cellular Biology. 16: 6677-6686. PMID 8943322  1
1996 Cellier K, Belouchi A, Gros P. Resistance to intracellular infections: Comparative genomic analysis of Nramp Trends in Genetics. 12: 201-204. PMID 8928221 DOI: 10.1016/0168-9525(96)30042-5  1
1996 Qureshi ST, Larivière L, Sebastiani G, Clermont S, Skamene E, Gros P, Malo D. A high-resolution map in the chromosomal region surrounding the Lps locus. Genomics. 31: 283-94. PMID 8838309 DOI: 10.1006/geno.1996.0050  1
1996 Jones JM, Ranscht B, Berglund EO, Gruenheid S, Gros P, Meisler MH. Close linkage of three neuronal genes on distal mouse chromosome 15. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 7: 696-7. PMID 8703126  1
1996 Hanna M, Brault M, Kwan T, Kast C, Gros P. Mutagenesis of transmembrane domain 11 of P-glycoprotein by alanine scanning. Biochemistry. 35: 3625-35. PMID 8639515 DOI: 10.1021/bi951333p  1
1996 Gros P, Hanna M. Chapter 7 The P-glycoprotein family and multidrug resistance: An overview Handbook of Biological Physics. 2: 137-163. DOI: 10.1016/S1383-8121(96)80048-0  1
1995 Belouchi A, Cellier M, Kwan T, Saini HS, Leroux G, Gros P. The macrophage-specific membrane protein Nramp controlling natural resistance to infections in mice has homologues expressed in the root system of plants. Plant Molecular Biology. 29: 1181-96. PMID 8616217 DOI: 10.1007/BF00020461  1
1995 Gruenheid S, Cellier M, Vidal S, Gros P. Identification and characterization of a second mouse Nramp gene. Genomics. 25: 514-25. PMID 7789986 DOI: 10.1016/0888-7543(95)80053-O  1
1995 Shustik C, Dalton W, Gros P. P-glycoprotein-mediated multidrug resistance in tumor cells: biochemistry, clinical relevance and modulation. Molecular Aspects of Medicine. 16: 1-78. PMID 7783568 DOI: 10.1016/0098-2997(94)00040-A  1
1995 Sebastiani G, Durocher D, Gros P, Nemer M, Malo D. Localization of the Catf1 transcription factor gene to mouse chromosome 19. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 6: 147-8. PMID 7767002 DOI: 10.1007/BF00303264  1
1995 Underhill DA, Vogan KJ, Gros P. Analysis of the mouse Splotch-delayed mutation indicates that the Pax-3 paired domain can influence homeodomain DNA-binding activity Proceedings of the National Academy of Sciences of the United States of America. 92: 3692-3696. PMID 7731966  1
1995 Vidal S, Tremblay ML, Govoni G, Gauthier S, Sebastiani G, Malo D, Skamene E, Olivier M, Jothy S, Gros P. The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene. The Journal of Experimental Medicine. 182: 655-66. PMID 7650477 DOI: 10.1084/jem.182.3.655  1
1995 Lepage P, Underhill DA, Gros P. Activation of a MMTV/mdr3 Fusion Transcript from a Cryptic Viral Promoter Is Stimulated by mdr-Derived Sequences Located in Intron I Virology. 210: 244-253. PMID 7618265 DOI: 10.1006/viro.1995.1341  1
1995 Beaudet L, Gros P. Functional dissection of p-glycoprotein nucleotide-binding domains in chimeric and mutant proteins: Modulation of drug resistance profiles Journal of Biological Chemistry. 270: 17159-17170. PMID 7615512 DOI: 10.1074/jbc.270.29.17159  1
1995 Mullick A, Trasler D, Gros P. High-resolution linkage map in the vicinity of the Lp locus Genomics. 26: 479-488. PMID 7607671 DOI: 10.1016/0888-7543(95)80166-J  1
1995 Ruetz S, Gros P. Enhancement of Mdr2-mediated phosphatidylcholine translocation by the bile salt taurocholate: Implications for hepatic bile formation Journal of Biological Chemistry. 270: 25388-25395. PMID 7592705  1
1995 Vidal S, Gros P, Skamene E. Natural resistance to infection with intracellular parasites: Molecular genetics identifies Nramp1 as the Bcg/Ity/Lsh locus Journal of Leukocyte Biology. 58: 382-390. PMID 7561513  1
1995 Cellier M, Privé G, Belouchi A, Kwan T, Rodrigues V, Chia W, Gros P. Nramp defines a family of membrane proteins Proceedings of the National Academy of Sciences of the United States of America. 92: 10089-10093. PMID 7479731 DOI: 10.1073/pnas.92.22.10089  1
1995 Gros P. Human (MDR1) and mouse (mdr1,mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators Biochemistry®. 34: 32-39.  1
1995 Lepage P, Gros P. P glycoprotein: From multidrug resistance to lipid transport Medecine/Sciences. 11: 357-366.  1
1994 Cellier M, Govoni G, Vidal S, Kwan T, Groulx N, Liu J, Sanchez F, Skamene E, Schurr E, Gros P. Human natural resistance-associated macrophage protein: cDNA cloning, chromosomal mapping, genomic organization, and tissue-specific expression. The Journal of Experimental Medicine. 180: 1741-52. PMID 7964458 DOI: 10.1084/jem.180.5.1741  1
1994 Ruetz S, Gros P. A mechanism for P-glycoprotein action in multidrug resistance: are we there yet? Trends in Pharmacological Sciences. 15: 260-263. PMID 7940990 DOI: 10.1016/0165-6147(94)90322-0  1
1994 Buschman E, Gros P. The Inability of the Mouse mdr2 Gene to Confer Multidrug Resistance Is Linked to Reduced Drug Binding to the Protein Cancer Research. 54: 4892-4898. PMID 7915194  1
1994 Ruetz S, Gros P. Phosphatidylcholine translocase: A physiological role for the mdr2 gene Cell. 77: 1071-1081. PMID 7912658 DOI: 10.1016/0092-8674(94)90446-4  1
1994 Ruetz S, Gros P. Functional expression of P-glycoproteins in secretory vesicles Journal of Biological Chemistry. 269: 12277-12284. PMID 7909318  1
1994 Buschman E, Lepage P, Gros P. P-glycoprotein homologues Cancer Treatment and Research. 73: 17-39. PMID 7536017  1
1993 Lepage P, Nepveu A, Raymond M, Gros P. Transcriptional Activation of the Mouse mdr3 Gene Coincides with the Appearance of Novel Transcription Initiation Sites in Multidrug-resistant P388 Tumor Cells Cancer Research. 53: 1657-1664. PMID 8453638  1
1993 Lepage P, Devault A, Gros P. Activation of the mouse mdr3 gene by insertion of retroviruses in multidrug-resistant P388 tumor cells Molecular and Cellular Biology. 13: 7380-7392. PMID 8246958  1
1993 Bibi E, Gros P, Kaback HR. Functional expression of mouse mdr1 in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 90: 9209-9213. PMID 8105473  1
1993 Gros P, Buschman E. The mouse multidrug resistance gene family: Structural and functional analysis International Review of Cytology. 137: 169-197. PMID 8098020  1
1993 Ruetz S, Raymond M, Gros P. Functional expression of P-glycoprotein encoded by the mouse mdr3 gene in yeast cells Proceedings of the National Academy of Sciences of the United States of America. 90: 11588-11592. PMID 7903452  1
1993 Lepage P, Gros P. Structural and functional aspects of P-glycoproteins and related transport proteins Current Opinion in Nephrology and Hypertension. 2: 735-743. PMID 7522912  1
1993 Gros P, Buschman E. The multidrug resistance transport protein: Identification of functional domains Journal of General Physiology. 101: 95-117.  1
1992 Dhir R, Gros P. Functional analysis of chimeric proteins constructed by exchanging homologous domains of two P-glycoproteins conferring distinct drug cesistance profiles Biochemistry. 31: 6103-6110. PMID 1352702  1
1991 Buschman E, Gros P. Functional Analysis of Chimeric Genes Obtained by Exchanging Homologous Domains of the Mouse mdr1 and mdr2 Genes Molecular and Cellular Biology. 11: 595-603. PMID 1990275  1
1991 Shustik C, Groulx N, Gros P. Analysis of multidrug resistance (MDR-1) gene expression in chronic lymphocytic leukaemia (CLL). British Journal of Haematology. 79: 50-6. PMID 1911388  1
1991 Schurr E, Skamene E, Gros P. Mapping of the gene coding for the muscle protein nebulin (Neb) to the proximal region of mouse chromosome 2 Cytogenetic and Genome Research. 57: 214-216. PMID 1683831 DOI: 10.1159/000133150  1
1991 Epstein DJ, Vekemans M, Gros P. splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3 Cell. 67: 767-774. PMID 1682057 DOI: 10.1016/0092-8674(91)90071-6  1
1991 Gros P, Shustik C. Multidrug resistance: A novel class of membrane-associated transport proteins is identified Cancer Investigation. 9: 563-569. PMID 1682020 DOI: 10.3109/07357909109018954  1
1990 Raymond M, Gros P. Cell-specific activity of as-acting regulatory elements in the promoter of the mouse multidrug resistance gene mdrl Molecular and Cellular Biology. 10: 6036-6040. PMID 2248681  1
1990 Dhir R, Buschman E, Gros P. Structural and functional characterization of the mouse multidrug resistance gene family Bulletin Du Cancer. 77: 1125-1129. PMID 1980424  1
1990 Devault A, Gros P. Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities Molecular and Cellular Biology. 10: 1652-1663. PMID 1969610  1
1989 Hammond JR, Johnstone RM, Gros P. Enhanced efflux of [3H]vinblastine from Chinese hamster ovary cells transfected with a full-length complementary DNA clone for the mdr1 gene. Cancer Research. 49: 3867-71. PMID 2736530  1
1989 Gros P, Malo D. A reverse genetics approach to Bcg/Ity/Lsh gene cloning Research in Immunology. 140: 774-777. PMID 2696049 DOI: 10.1016/0923-2494(89)90031-X  1
1989 Azzaria M, Schurr E, Gros P. Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance Molecular and Cellular Biology. 9: 5289-5297. PMID 2573836  1
1988 Croop JM, Gros P, Housman DE. Genetics of multidrug resistance. The Journal of Clinical Investigation. 81: 1303-9. PMID 3284909 DOI: 10.1172/JCI113455  1
1988 Lemontt JF, Azzaria M, Gros P. Increased mdr Gene Expression and Decreased Drug Accumulation in Multidrug-resistant Human Melanoma Cells Cancer Research. 48: 6348-6353. PMID 3180053  1
1986 Gros P, Croop J, Housman D. Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins. Cell. 47: 371-80. PMID 3768958 DOI: 10.1016/0092-8674(86)90594-5  1
1984 Heinrich G, Gros P, Habener JF. Glucagon gene sequence. Four of six exons encode separate functional domains of rat pre-proglucagon. The Journal of Biological Chemistry. 259: 14082-7. PMID 6094539  1
1983 Gros P, Skamene E, Forget A. Cellular mechanisms of genetically controlled host resistance to Mycobacterium bovis (BCG) Journal of Immunology. 131: 1966-1972. PMID 6311901  1
1983 Skamene E, Gros P. Role of macrophages in resistance against infectious diseases Clinics in Immunology and Allergy. 3: 539-560.  1
1981 Gros P, Skamene E, Forget A. Genetic control of natural resistance to Mycobacterium bovis (BCG) in mice Journal of Immunology. 127: 2417-2421. PMID 6795274  1
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