Samantha Gruenheid, Ph.D. - Publications

Affiliations: 
2000 McGill University, Montreal, QC, Canada 
Area:
Molecular Biology, Biochemistry

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Kang E, Yousefi M, Gruenheid S. R-Spondins Are Expressed by the Intestinal Stroma and are Differentially Regulated during Citrobacter rodentium- and DSS-Induced Colitis in Mice. Plos One. 11: e0152859. PMID 27046199 DOI: 10.1371/journal.pone.0152859  0.4
2015 Brannon JR, Thomassin JL, Gruenheid S, Le Moual H. Antimicrobial Peptide Conformation as a Structural Determinant of Omptin Protease Specificity. Journal of Bacteriology. 197: 3583-91. PMID 26350132 DOI: 10.1128/JB.00469-15  0.4
2015 Brannon JR, Burk DL, Leclerc JM, Thomassin JL, Portt A, Berghuis AM, Gruenheid S, Le Moual H. Inhibition of outer membrane proteases of the omptin family by aprotinin. Infection and Immunity. 83: 2300-11. PMID 25824836 DOI: 10.1128/IAI.00136-15  0.4
2015 Cloutier M, Gauthier C, Fortin JS, Genève L, Kim K, Gruenheid S, Kim J, Thibodeau J. ER egress of invariant chain isoform p35 requires direct binding to MHCII molecules and is inhibited by the NleA virulence factor of enterohaemorrhagic Escherichia coli. Human Immunology. 76: 292-6. PMID 25731712 DOI: 10.1016/j.humimm.2015.02.002  0.4
2015 Thomassin JL, Giannakopoulou N, Zhu L, Gross J, Salmon K, Leclerc JM, Daigle F, Le Moual H, Gruenheid S. The CpxRA two-component system is essential for Citrobacter rodentium virulence. Infection and Immunity. 83: 1919-28. PMID 25712925 DOI: 10.1128/IAI.00194-15  0.4
2014 Premjani V, Tilley D, Gruenheid S, Le Moual H, Samis JA. Enterohemorrhagic Escherichia coli OmpT regulates outer membrane vesicle biogenesis. Fems Microbiology Letters. 355: 185-92. PMID 24813639 DOI: 10.1111/1574-6968.12463  0.4
2014 Dauphinee SM, Richer E, Eva MM, McIntosh F, Paquet M, Dangoor D, Burkart C, Zhang DE, Gruenheid S, Gros P, Behr M, Malo D. Contribution of increased ISG15, ISGylation and deregulated type I IFN signaling in Usp18 mutant mice during the course of bacterial infections. Genes and Immunity. 15: 282-92. PMID 24807690 DOI: 10.1038/gene.2014.17  0.4
2013 Thomassin JL, Lee MJ, Brannon JR, Sheppard DC, Gruenheid S, Le Moual H. Both group 4 capsule and lipopolysaccharide O-antigen contribute to enteropathogenic Escherichia coli resistance to human α-defensin 5. Plos One. 8: e82475. PMID 24324796 DOI: 10.1371/journal.pone.0082475  0.4
2013 Papapietro O, Gruenheid S. [Rspo2 controls C. rodentium infection outcome in mice]. MéDecine Sciences : M/S. 29: 688-90. PMID 24005619 DOI: 10.1051/medsci/2013298003  0.4
2013 Thanabalasuriar A, Kim J, Gruenheid S. The inhibition of COPII trafficking is important for intestinal epithelial tight junction disruption during enteropathogenic Escherichia coli and Citrobacter rodentium infection. Microbes and Infection / Institut Pasteur. 15: 738-44. PMID 23747681 DOI: 10.1016/j.micinf.2013.05.001  0.4
2013 Brannon JR, Thomassin JL, Desloges I, Gruenheid S, Le Moual H. Role of uropathogenic Escherichia coli OmpT in the resistance against human cathelicidin LL-37. Fems Microbiology Letters. 345: 64-71. PMID 23710656 DOI: 10.1111/1574-6968.12185  0.4
2013 Papapietro O, Teatero S, Thanabalasuriar A, Yuki KE, Diez E, Zhu L, Kang E, Dhillon S, Muise AM, Durocher Y, Marcinkiewicz MM, Malo D, Gruenheid S. R-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea. Nature Communications. 4: 1898. PMID 23695692 DOI: 10.1038/ncomms2816  0.4
2013 Comery R, Thanabalasuriar A, Garneau P, Portt A, Boerlin P, Reid-Smith RJ, Harel J, Manges AR, Gruenheid S. Identification of potentially diarrheagenic atypical enteropathogenic Escherichia coli strains present in Canadian food animals at slaughter and in retail meats. Applied and Environmental Microbiology. 79: 3892-6. PMID 23584785 DOI: 10.1128/AEM.00182-13  0.4
2012 Thomassin JL, Brannon JR, Kaiser J, Gruenheid S, Le Moual H. Enterohemorrhagic and enteropathogenic Escherichia coli evolved different strategies to resist antimicrobial peptides. Gut Microbes. 3: 556-61. PMID 22895086 DOI: 10.4161/gmic.21656  0.4
2012 Thanabalasuriar A, Bergeron J, Gillingham A, Mimee M, Thomassin JL, Strynadka N, Kim J, Gruenheid S. Sec24 interaction is essential for localization and virulence-associated function of the bacterial effector protein NleA. Cellular Microbiology. 14: 1206-18. PMID 22432415 DOI: 10.1111/j.1462-5822.2012.01789.x  0.4
2012 Bongfen SE, Rodrigue-Gervais IG, Berghout J, Torre S, Cingolani P, Wiltshire SA, Leiva-Torres GA, Letourneau L, Sladek R, Blanchette M, Lathrop M, Behr MA, Gruenheid S, Vidal SM, Saleh M, et al. An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria. Plos One. 7: e31012. PMID 22363534 DOI: 10.1371/journal.pone.0031012  0.4
2012 Gruenheid S, Le Moual H. Resistance to antimicrobial peptides in Gram-negative bacteria. Fems Microbiology Letters. 330: 81-9. PMID 22339775 DOI: 10.1111/j.1574-6968.2012.02528.x  0.4
2012 Thomassin JL, Brannon JR, Gibbs BF, Gruenheid S, Le Moual H. OmpT outer membrane proteases of enterohemorrhagic and enteropathogenic Escherichia coli contribute differently to the degradation of human LL-37. Infection and Immunity. 80: 483-92. PMID 22144482 DOI: 10.1128/IAI.05674-11  0.4
2011 Harmidy K, Tufenkji N, Gruenheid S. Perturbation of host cell cytoskeleton by cranberry proanthocyanidins and their effect on enteric infections. Plos One. 6: e27267. PMID 22076143 DOI: 10.1371/journal.pone.0027267  0.4
2011 Teatero SA, Thomassin JL, Zhu L, Diez E, Malo D, Gruenheid S. The Cri1 locus is the common genetic cause of susceptibility to Citrobacter rodentium infection in C3H and FVB mouse strains. Gut Microbes. 2: 173-7. PMID 21804358  0.4
2011 Diez E, Zhu L, Teatero SA, Paquet M, Roy MF, Loredo-Osti JC, Malo D, Gruenheid S. Identification and characterization of Cri1, a locus controlling mortality during Citrobacter rodentium infection in mice. Genes and Immunity. 12: 280-90. PMID 21326319 DOI: 10.1038/gene.2010.76  0.4
2011 Huang J, Birmingham CL, Shahnazari S, Shiu J, Zheng YT, Smith AC, Campellone KG, Heo WD, Gruenheid S, Meyer T, Welch MD, Ktistakis NT, Kim PK, Klionsky DJ, Brumell JH. Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase. Autophagy. 7: 17-26. PMID 20980813 DOI: 10.4161/auto.7.1.13840  0.4
2010 Thanabalasuriar A, Koutsouris A, Hecht G, Gruenheid S. The bacterial virulence factor NleA's involvement in intestinal tight junction disruption during enteropathogenic E. coli infection is independent of its putative PDZ binding domain. Gut Microbes. 1: 114-118. PMID 21326920 DOI: 10.4161/gmic.1.2.11685  0.4
2010 Gruenheid S, Gros P. Forward genetic dissection of innate response to infection in inbred mouse strains: selected success stories. Clinical and Experimental Immunology. 162: 393-401. PMID 21070206 DOI: 10.1111/j.1365-2249.2010.04249.x  0.4
2010 Thanabalasuriar A, Koutsouris A, Weflen A, Mimee M, Hecht G, Gruenheid S. The bacterial virulence factor NleA is required for the disruption of intestinal tight junctions by enteropathogenic Escherichia coli. Cellular Microbiology. 12: 31-41. PMID 19712078 DOI: 10.1111/j.1462-5822.2009.01376.x  0.4
2009 Le Sage V, Zhu L, Lepage C, Portt A, Viau C, Daigle F, Gruenheid S, Le Moual H. An outer membrane protease of the omptin family prevents activation of the Citrobacter rodentium PhoPQ two-component system by antimicrobial peptides. Molecular Microbiology. 74: 98-111. PMID 19708916 DOI: 10.1111/j.1365-2958.2009.06854.x  0.4
2008 Zhang AS, Canonne-Hergaux F, Gruenheid S, Gros P, Ponka P. Use of Nramp2-transfected Chinese hamster ovary cells and reticulocytes from mk/mk mice to study iron transport mechanisms. Experimental Hematology. 36: 1227-35. PMID 18722041 DOI: 10.1016/j.exphem.2008.04.014  0.4
2008 LeBlanc PM, Yeretssian G, Rutherford N, Doiron K, Nadiri A, Zhu L, Green DR, Gruenheid S, Saleh M. Caspase-12 modulates NOD signaling and regulates antimicrobial peptide production and mucosal immunity. Cell Host & Microbe. 3: 146-57. PMID 18329614 DOI: 10.1016/j.chom.2008.02.004  0.4
2008 Echtenkamp F, Deng W, Wickham ME, Vazquez A, Puente JL, Thanabalasuriar A, Gruenheid S, Finlay BB, Hardwidge PR. Characterization of the NleF effector protein from attaching and effacing bacterial pathogens. Fems Microbiology Letters. 281: 98-107. PMID 18279332 DOI: 10.1111/j.1574-6968.2008.01088.x  0.4
2008 Coombes BK, Wickham ME, Mascarenhas M, Gruenheid S, Finlay BB, Karmali MA. Molecular analysis as an aid to assess the public health risk of non-O157 Shiga toxin-producing Escherichia coli strains. Applied and Environmental Microbiology. 74: 2153-60. PMID 18245257 DOI: 10.1128/AEM.02566-07  0.4
2008 Blasutig IM, New LA, Thanabalasuriar A, Dayarathna TK, Goudreault M, Quaggin SE, Li SS, Gruenheid S, Jones N, Pawson T. Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization. Molecular and Cellular Biology. 28: 2035-46. PMID 18212058 DOI: 10.1128/MCB.01770-07  0.4
2007 Kim J, Thanabalasuriar A, Chaworth-Musters T, Fromme JC, Frey EA, Lario PI, Metalnikov P, Rizg K, Thomas NA, Lee SF, Hartland EL, Hardwidge PR, Pawson T, Strynadka NC, Finlay BB, ... ... Gruenheid S, et al. The bacterial virulence factor NleA inhibits cellular protein secretion by disrupting mammalian COPII function. Cell Host & Microbe. 2: 160-71. PMID 18005731 DOI: 10.1016/j.chom.2007.07.010  0.4
2005 Deng W, Li Y, Hardwidge PR, Frey EA, Pfuetzner RA, Lee S, Gruenheid S, Strynakda NC, Puente JL, Finlay BB. Regulation of type III secretion hierarchy of translocators and effectors in attaching and effacing bacterial pathogens. Infection and Immunity. 73: 2135-46. PMID 15784556 DOI: 10.1128/IAI.73.4.2135-2146.2005  0.4
2004 Deng W, Puente JL, Gruenheid S, Li Y, Vallance BA, Vázquez A, Barba J, Ibarra JA, O'Donnell P, Metalnikov P, Ashman K, Lee S, Goode D, Pawson T, Finlay BB. Dissecting virulence: systematic and functional analyses of a pathogenicity island. Proceedings of the National Academy of Sciences of the United States of America. 101: 3597-602. PMID 14988506 DOI: 10.1073/pnas.0400326101  0.4
2004 Gruenheid S, Sekirov I, Thomas NA, Deng W, O'Donnell P, Goode D, Li Y, Frey EA, Brown NF, Metalnikov P, Pawson T, Ashman K, Finlay BB. Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7. Molecular Microbiology. 51: 1233-49. PMID 14982621 DOI: 10.1046/j.1365-2958.2003.03911.x  0.4
2004 Vallance BA, Khan MA, Deng W, Gruenheid S, Finlay BB. Modeling enteropathogenic and enterohemorrhagic E. coli infections and disease Drug Discovery Today: Disease Models. 1: 73-79. DOI: 10.1016/j.ddmod.2004.04.001  0.4
2003 Gruenheid S, Finlay BB. Microbial pathogenesis and cytoskeletal function. Nature. 422: 775-81. PMID 12700772 DOI: 10.1038/nature01603  0.4
2002 Jabado N, Canonne-Hergaux F, Gruenheid S, Picard V, Gros P. Iron transporter Nramp2/DMT-1 is associated with the membrane of phagosomes in macrophages and Sertoli cells. Blood. 100: 2617-22. PMID 12239176 DOI: 10.1182/blood-2002-04-1182  0.4
2002 Zaharik ML, Gruenheid S, Perrin AJ, Finlay BB. Delivery of dangerous goods: type III secretion in enteric pathogens. International Journal of Medical Microbiology : Ijmm. 291: 593-603. PMID 12008913 DOI: 10.1078/1438-4221-00179  0.4
2001 Gruenheid S, DeVinney R, Bladt F, Goosney D, Gelkop S, Gish GD, Pawson T, Finlay BB. Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells Nature Cell Biology. 3: 856-859. PMID 11533668 DOI: 10.1038/ncb0901-856  0.4
2000 Gruenheid S, Finlay BB. Crowd control: Quorum sensing in pathogenic E. coli Trends in Microbiology. 8: 442-443. PMID 11044672 DOI: 10.1016/S0966-842X(00)01818-7  0.4
2000 Goosney DL, Gruenheid S, Finlay BB. Gut feelings: Enteropathogenic E. coli (EPEC) interactions with the host Annual Review of Cell and Developmental Biology. 16: 173-189. PMID 11031234 DOI: 10.1146/annurev.cellbio.16.1.173  0.4
2000 Kwan T, Loughrey H, Brault M, Gruenheid S, Urbatsch IL, Senior AE, Gros P. Functional analysis of a tryptophan-less P-glycoprotein: a tool for tryptophan insertion and fluorescence spectroscopy. Molecular Pharmacology. 58: 37-47. PMID 10860925  0.4
2000 Gruenheid S, Gros P. Genetic susceptibility to intracellular infections: Nramp1, macrophage function and divalent cations transport. Current Opinion in Microbiology. 3: 43-8. PMID 10679418 DOI: 10.1016/S1369-5274(99)00049-1  0.4
1999 Canonne-Hergaux F, Gruenheid S, Govoni G, Gros P. The Nramp1 protein and its role in resistance to infection and macrophage function. Proceedings of the Association of American Physicians. 111: 283-9. PMID 10417735 DOI: 10.1046/j.1525-1381.1999.99236.x  0.4
1999 Canonne-Hergaux F, Gruenheid S, Ponka P, Gros P. Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron. Blood. 93: 4406-17. PMID 10361139  0.4
1999 Gruenheid S, Canonne-Hergaux F, Gauthier S, Hackam DJ, Grinstein S, Gros P. The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes. The Journal of Experimental Medicine. 189: 831-41. PMID 10049947 DOI: 10.1084/jem.189.5.831  0.4
1999 Gruenheid S, Skamene E, Gros P. Nramp1. A novel macrophage protein with a key function in resistance to intracellular pathogens Advances in Cellular and Molecular Biology of Membranes and Organelles. 5: 345-362. DOI: 10.1016/S1874-5172(99)80039-X  0.4
1998 Hackam DJ, Rotstein OD, Zhang W, Gruenheid S, Gros P, Grinstein S. Host resistance to intracellular infection: mutation of natural resistance-associated macrophage protein 1 (Nramp1) impairs phagosomal acidification. The Journal of Experimental Medicine. 188: 351-64. PMID 9670047 DOI: 10.1084/jem.188.2.351  0.4
1997 Pinner E, Gruenheid S, Raymond M, Gros P. Functional complementation of the yeast divalent cation transporter family SMF by NRAMP2, a member of the mammalian natural resistance-associated macrophage protein family. The Journal of Biological Chemistry. 272: 28933-8. PMID 9360964 DOI: 10.1074/jbc.272.46.28933  0.4
1997 Gruenheid S, Pinner E, Desjardins M, Gros P. Natural resistance to infection with intracellular pathogens: the Nramp1 protein is recruited to the membrane of the phagosome. The Journal of Experimental Medicine. 185: 717-30. PMID 9034150 DOI: 10.1084/jem.185.4.717  0.4
1996 Jones JM, Ranscht B, Berglund EO, Gruenheid S, Gros P, Meisler MH. Close linkage of three neuronal genes on distal mouse chromosome 15. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 7: 696-7. PMID 8703126  0.4
1995 Gruenheid S, Cellier M, Vidal S, Gros P. Identification and characterization of a second mouse Nramp gene. Genomics. 25: 514-25. PMID 7789986 DOI: 10.1016/0888-7543(95)80053-O  0.4
1993 Gruenheid S, Gatzke L, Meadows H, Tufaro F. Herpes simplex virus infection and propagation in a mouse L cell mutant lacking heparan sulfate proteoglycans Journal of Virology. 67: 93-100. PMID 8380101  0.4
1992 Michaelis C, Banfield BW, Gruenheid S, Tsang Y, Lippe R, Jefferies WA, Wattenberg BW, Tufaro F. Toxin resistance and reduced secretion in a mouse L-cell mutant defective in herpes virus propagation Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 70: 1209-1217. PMID 1338412  0.4
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