| Year |
Citation |
Score |
| 2024 |
Speaks S, McFadden MI, Zani A, Solstad A, Leumi S, Roettger JE, Kenney AD, Bone H, Zhang L, Denz PJ, Eddy AC, Amer AO, Robinson RT, Cai C, Ma J, et al. Gasdermin D promotes influenza virus-induced mortality through neutrophil amplification of inflammation. Nature Communications. 15: 2751. PMID 38553499 DOI: 10.1038/s41467-024-47067-0 |
0.304 |
|
| 2023 |
Speaks S, Zani A, Solstad A, Kenney A, Zhang L, Eddy AC, Amer AO, Robinson R, Cai C, Ma J, Hemann EA, Forero A, Yount JS. Loss of Gasdermin D is protective against influenza virus-induced inflammation and mortality. Biorxiv : the Preprint Server For Biology. PMID 36945485 DOI: 10.1101/2023.03.08.531787 |
0.301 |
|
| 2022 |
Eltobgy MM, Zani A, Kenney AD, Estfanous S, Kim E, Badr A, Carafice C, Daily K, Whitham O, Pietrzak M, Webb A, Kawahara J, Eddy AC, Denz P, Lu M, ... ... Amer AO, et al. Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and immunothrombosis. Proceedings of the National Academy of Sciences of the United States of America. 119: e2202012119. PMID 35588457 DOI: 10.1073/pnas.2202012119 |
0.395 |
|
| 2022 |
Badr A, Eltobgy M, Krause K, Hamilton K, Estfanous S, Daily KP, Abu Khweek A, Hegazi A, Anne MNK, Carafice C, Robledo-Avila F, Saqr Y, Zhang X, Bonfield TL, Gavrilin MA, ... ... Amer AO, et al. CFTR Modulators Restore Acidification of Autophago-Lysosomes and Bacterial Clearance in Cystic Fibrosis Macrophages. Frontiers in Cellular and Infection Microbiology. 12: 819554. PMID 35252032 DOI: 10.3389/fcimb.2022.819554 |
0.311 |
|
| 2021 |
Abu Khweek A, Joldrichsen MR, Kim E, Attia Z, Krause K, Daily K, Estfanous S, Hamilton K, Badr A, Anne MNK, Eltobgy M, Corps KN, Carafice C, Zhang X, Gavrilin MA, ... ... Amer AO, et al. Caspase-11 regulates lung inflammation in response to house dust mites. Cellular Immunology. 370: 104425. PMID 34800762 DOI: 10.1016/j.cellimm.2021.104425 |
0.338 |
|
| 2021 |
Azari S, Johnson LJ, Webb A, Kozlowski SM, Zhang X, Rood K, Amer A, Seveau S. Hofbauer Cells Spread Listeria monocytogenes among Placental Cells and Undergo Pro-Inflammatory Reprogramming while Retaining Production of Tolerogenic Factors. Mbio. e0184921. PMID 34399615 DOI: 10.1128/mBio.01849-21 |
0.367 |
|
| 2021 |
Estfanous S, Krause K, Anne MNK, Eltobgy M, Caution K, Abu Khweek A, Hamilton K, Badr A, Daily K, Carafice C, Baetzhold D, Zhang X, Li T, Wen H, Gavrilin MA, ... ... Amer AO, et al. Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo. Scientific Reports. 11: 855. PMID 33441602 DOI: 10.1038/s41598-020-79201-5 |
0.423 |
|
| 2020 |
Hamilton K, Krause K, Badr A, Daily K, Estfanous S, Eltobgy M, Khweek AA, Anne MNK, Carafice C, Baetzhold D, Tonniges JR, Zhang X, Gavrilin MA, Parinandi NL, Amer AO. Defective immunometabolism pathways in cystic fibrosis macrophages. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 33208300 DOI: 10.1016/j.jcf.2020.10.006 |
0.328 |
|
| 2020 |
Abu Khweek A, Amer AO. Pyroptotic and non-pyroptotic effector functions of caspase-11. Immunological Reviews. e12910. PMID 32737894 DOI: 10.1111/imr.12910 |
0.383 |
|
| 2019 |
Caution K, Young N, Robledo-Avila F, Krause K, Abu Khweek A, Hamilton K, Badr A, Vaidya A, Daily K, Gosu H, Anne MNK, Eltobgy M, Dakhlallah D, Argwal S, Estfanous S, ... ... Amer AO, et al. Caspase-11 Mediates Neutrophil Chemotaxis and Extracellular Trap Formation During Acute Gouty Arthritis Through Alteration of Cofilin Phosphorylation. Frontiers in Immunology. 10: 2519. PMID 31803174 DOI: 10.3389/fimmu.2019.02519 |
0.378 |
|
| 2019 |
Krause K, Daily K, Estfanous S, Hamilton K, Badr A, Abu Khweek A, Hegazi R, Anne MN, Klamer B, Zhang X, Gavrilin MA, Pancholi V, Amer AO. Caspase-11 counteracts mitochondrial ROS-mediated clearance of Staphylococcus aureus in macrophages. Embo Reports. e48109. PMID 31637841 DOI: 10.15252/Embr.201948109 |
0.309 |
|
| 2019 |
Caution K, Pan A, Krause K, Badr A, Hamilton K, Vaidya A, Gosu H, Daily K, Estfanous S, Gavrilin MA, Drew ME, Cormet-Boyaka E, Chen X, Frankhouser DE, Bundschuh R, ... ... Amer AO, et al. Methylomic correlates of autophagy activity in cystic fibrosis. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 30737168 DOI: 10.1016/J.Jcf.2019.01.011 |
0.337 |
|
| 2018 |
Krause K, Caution K, Badr A, Hamilton K, Saleh A, Patel K, Seveau S, Hall-Stoodley L, Hegazi R, Zhang X, Gavrilin MA, Amer AO. CASP4/caspase-11 promotes autophagosome formation in response to bacterial infection. Autophagy. 1-15. PMID 30165781 DOI: 10.1080/15548627.2018.1491494 |
0.453 |
|
| 2018 |
Robledo-Avila FH, Ruiz-Rosado JD, Brockman KL, Kopp BT, Amer AO, McCoy K, Bakaletz LO, Partida-Sanchez S. Dysregulated Calcium Homeostasis in Cystic Fibrosis Neutrophils Leads to Deficient Antimicrobial Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 30120123 DOI: 10.4049/Jimmunol.1800076 |
0.32 |
|
| 2018 |
Liu F, Krause K, Amer A, Hall-Stoodley L, Reilly J, Nichols A. EPS1.05 CAT-5571 restores autophagy, a fundamental defect in cystic fibrosis, and is a potential new treatment for people with cystic fibrosis Journal of Cystic Fibrosis. 17: S38. DOI: 10.1016/S1569-1993(18)30236-4 |
0.304 |
|
| 2017 |
Seveau S, Turner J, Gavrilin MA, Torrelles JB, Hall-Stoodley L, Yount J, Amer AO. Checks and Balances between Autophagy and the Inflammasomes during Infection. Journal of Molecular Biology. PMID 29162504 DOI: 10.1016/J.Jmb.2017.11.006 |
0.358 |
|
| 2017 |
Shrestha CL, Assani KD, Rinehardt H, Albastroiu F, Zhang S, Shell R, Amer AO, Schlesinger LS, Kopp BT. Cysteamine-mediated clearance of antibiotic-resistant pathogens in human cystic fibrosis macrophages. Plos One. 12: e0186169. PMID 28982193 DOI: 10.1371/Journal.Pone.0186169 |
0.452 |
|
| 2016 |
Krause K, Amer AO. Caspase Exploitation by Legionella pneumophila. Frontiers in Microbiology. 7: 515. PMID 27148204 DOI: 10.3389/fmicb.2016.00515 |
0.47 |
|
| 2016 |
Abu Khweek A, Kanneganti A, C Guttridge D D, Amer AO. The Sphingosine-1-Phosphate Lyase (LegS2) Contributes to the Restriction of Legionella pneumophila in Murine Macrophages. Plos One. 11: e0146410. PMID 26741365 DOI: 10.1371/journal.pone.0146410 |
0.476 |
|
| 2015 |
Abdelaziz DH, Khalil H, Cormet-Boyaka E, Amer AO. The cooperation between the autophagy machinery and the inflammasome to implement an appropriate innate immune response: do they regulate each other? Immunological Reviews. 265: 194-204. PMID 25879294 DOI: 10.1111/imr.12288 |
0.315 |
|
| 2014 |
Assani K, Tazi MF, Amer AO, Kopp BT. IFN-γ stimulates autophagy-mediated clearance of Burkholderia cenocepacia in human cystic fibrosis macrophages. Plos One. 9: e96681. PMID 24798083 DOI: 10.1371/Journal.Pone.0096681 |
0.385 |
|
| 2013 |
Novotny LA, Amer AO, Brockson ME, Goodman SD, Bakaletz LO. Structural stability of Burkholderia cenocepacia biofilms is reliant on eDNA structure and presence of a bacterial nucleic acid binding protein. Plos One. 8: e67629. PMID 23799151 DOI: 10.1371/journal.pone.0067629 |
0.31 |
|
| 2013 |
Abu Khweek A, Fernández Dávila NS, Caution K, Akhter A, Abdulrahman BA, Tazi M, Hassan H, Novotny LA, Bakaletz LO, Amer AO. Biofilm-derived Legionella pneumophila evades the innate immune response in macrophages. Frontiers in Cellular and Infection Microbiology. 3: 18. PMID 23750338 DOI: 10.3389/Fcimb.2013.00018 |
0.746 |
|
| 2013 |
Aeffner F, Abdulrahman B, Hickman-Davis JM, Janssen PM, Amer A, Bedwell DM, Sorscher EJ, Davis IC. Heterozygosity for the F508del mutation in the cystic fibrosis transmembrane conductance regulator anion channel attenuates influenza severity. The Journal of Infectious Diseases. 208: 780-9. PMID 23749967 DOI: 10.1093/Infdis/Jit251 |
0.679 |
|
| 2013 |
Khweek AA, Caution K, Akhter A, Abdulrahman BA, Tazi M, Hassan H, Majumdar N, Doran A, Guirado E, Schlesinger LS, Shuman H, Amer AO. A bacterial protein promotes the recognition of the Legionella pneumophila vacuole by autophagy. European Journal of Immunology. 43: 1333-44. PMID 23420491 DOI: 10.1002/Eji.201242835 |
0.723 |
|
| 2013 |
Abdulrahman BA, Khweek AA, Akhter A, Caution K, Tazi M, Hassan H, Zhang Y, Rowland PD, Malhotra S, Aeffner F, Davis IC, Valvano MA, Amer AO. Depletion of the ubiquitin-binding adaptor molecule SQSTM1/p62 from macrophages harboring cftr ΔF508 mutation improves the delivery of Burkholderia cenocepacia to the autophagic machinery. The Journal of Biological Chemistry. 288: 2049-58. PMID 23148214 DOI: 10.1074/Jbc.M112.411728 |
0.736 |
|
| 2012 |
Rosales-Reyes R, Aubert DF, Tolman JS, Amer AO, Valvano MA. Burkholderia cenocepacia type VI secretion system mediates escape of type II secreted proteins into the cytoplasm of infected macrophages. Plos One. 7: e41726. PMID 22848580 DOI: 10.1371/journal.pone.0041726 |
0.425 |
|
| 2012 |
Kopp BT, Abdulrahman BA, Khweek AA, Kumar SB, Akhter A, Montione R, Tazi MF, Caution K, McCoy K, Amer AO. Exaggerated inflammatory responses mediated by Burkholderia cenocepacia in human macrophages derived from Cystic fibrosis patients. Biochemical and Biophysical Research Communications. 424: 221-7. PMID 22728038 DOI: 10.1016/J.Bbrc.2012.06.066 |
0.739 |
|
| 2012 |
Akhter A, Caution K, Abu Khweek A, Tazi M, Abdulrahman BA, Abdelaziz DH, Voss OH, Doseff AI, Hassan H, Azad AK, Schlesinger LS, Wewers MD, Gavrilin MA, Amer AO. Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization. Immunity. 37: 35-47. PMID 22658523 DOI: 10.1016/J.Immuni.2012.05.001 |
0.749 |
|
| 2012 |
Gavrilin MA, Abdelaziz DH, Mostafa M, Abdulrahman BA, Grandhi J, Akhter A, Abu Khweek A, Aubert DF, Valvano MA, Wewers MD, Amer AO. Activation of the pyrin inflammasome by intracellular Burkholderia cenocepacia. Journal of Immunology (Baltimore, Md. : 1950). 188: 3469-77. PMID 22368275 DOI: 10.4049/Jimmunol.1102272 |
0.739 |
|
| 2011 |
Hassan H, Amer AO. Cell intrinsic roles of apoptosis-associated speck-like protein in regulating innate and adaptive immune responses. Thescientificworldjournal. 11: 2418-23. PMID 22194672 DOI: 10.1100/2011/429192 |
0.387 |
|
| 2011 |
Anand PK, Tait SW, Lamkanfi M, Amer AO, Nunez G, Pagès G, Pouysségur J, McGargill MA, Green DR, Kanneganti TD. TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation. The Journal of Biological Chemistry. 286: 42981-91. PMID 22033934 DOI: 10.1074/Jbc.M111.310599 |
0.405 |
|
| 2011 |
Abdulrahman BA, Khweek AA, Akhter A, Caution K, Kotrange S, Abdelaziz DH, Newland C, Rosales-Reyes R, Kopp B, McCoy K, Montione R, Schlesinger LS, Gavrilin MA, Wewers MD, Valvano MA, ... Amer AO, et al. Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis. Autophagy. 7: 1359-70. PMID 21997369 DOI: 10.4161/Auto.7.11.17660 |
0.747 |
|
| 2011 |
Abdelaziz DH, Gavrilin MA, Akhter A, Caution K, Kotrange S, Khweek AA, Abdulrahman BA, Hassan ZA, El-Sharkawi FZ, Bedi SS, Ladner K, Gonzalez-Mejia ME, Doseff AI, Mostafa M, Kanneganti TD, ... ... Amer AO, et al. Asc-dependent and independent mechanisms contribute to restriction of legionella pneumophila infection in murine macrophages. Frontiers in Microbiology. 2: 18. PMID 21713115 DOI: 10.3389/Fmicb.2011.00018 |
0.763 |
|
| 2011 |
Amer AO. The inflammasome. Frontiers in Microbiology. 2: 4. PMID 21713058 DOI: 10.3389/fmicb.2011.00004 |
0.333 |
|
| 2011 |
Kotrange S, Kopp B, Akhter A, Abdelaziz D, Abu Khweek A, Caution K, Abdulrahman B, Wewers MD, McCoy K, Marsh C, Loutet SA, Ortega X, Valvano MA, Amer AO. Burkholderia cenocepacia O polysaccharide chain contributes to caspase-1-dependent IL-1beta production in macrophages. Journal of Leukocyte Biology. 89: 481-8. PMID 21178113 DOI: 10.1189/Jlb.0910513 |
0.744 |
|
| 2011 |
Abdelaziz DH, Gavrilin MA, Akhter A, Caution K, Kotrange S, Khweek AA, Abdulrahman BA, Grandhi J, Hassan ZA, Marsh C, Wewers MD, Amer AO. Apoptosis-associated speck-like protein (ASC) controls Legionella pneumophila infection in human monocytes. The Journal of Biological Chemistry. 286: 3203-8. PMID 21097506 DOI: 10.1074/jbc.M110.197681 |
0.755 |
|
| 2010 |
Khweek AA, Amer A. Replication of Legionella Pneumophila in Human Cells: Why are We Susceptible? Frontiers in Microbiology. 1: 133. PMID 21687775 DOI: 10.3389/Fmicb.2010.00133 |
0.427 |
|
| 2010 |
Lamkanfi M, Sarkar A, Vande Walle L, Vitari AC, Amer AO, Wewers MD, Tracey KJ, Kanneganti TD, Dixit VM. Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia. Journal of Immunology (Baltimore, Md. : 1950). 185: 4385-92. PMID 20802146 DOI: 10.4049/Jimmunol.1000803 |
0.365 |
|
| 2010 |
Butchar JP, Mehta P, Justiniano SE, Guenterberg KD, Kondadasula SV, Mo X, Chemudupati M, Kanneganti TD, Amer A, Muthusamy N, Jarjoura D, Marsh CB, Carson WE, Byrd JC, Tridandapani S. Reciprocal regulation of activating and inhibitory Fc{gamma} receptors by TLR7/8 activation: implications for tumor immunotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 2065-75. PMID 20332325 DOI: 10.1158/1078-0432.Ccr-09-2591 |
0.304 |
|
| 2010 |
Abdelaziz DH, Amr K, Amer AO. Nlrc4/Ipaf/CLAN/CARD12: more than a flagellin sensor. The International Journal of Biochemistry & Cell Biology. 42: 789-91. PMID 20067841 DOI: 10.1016/j.biocel.2010.01.003 |
0.35 |
|
| 2009 |
Rajaram MV, Butchar JP, Parsa KV, Cremer TJ, Amer A, Schlesinger LS, Tridandapani S. Akt and SHIP modulate Francisella escape from the phagosome and induction of the Fas-mediated death pathway. Plos One. 4: e7919. PMID 19936232 DOI: 10.1371/Journal.Pone.0007919 |
0.337 |
|
| 2009 |
Akhter A, Gavrilin MA, Frantz L, Washington S, Ditty C, Limoli D, Day C, Sarkar A, Newland C, Butchar J, Marsh CB, Wewers MD, Tridandapani S, Kanneganti TD, Amer AO. Caspase-7 activation by the Nlrc4/Ipaf inflammasome restricts Legionella pneumophila infection. Plos Pathogens. 5: e1000361. PMID 19343209 DOI: 10.1371/Journal.Ppat.1000361 |
0.49 |
|
| 2009 |
Butchar JP, Mehta P, Justiniano SE, Guenterberg KD, Kanneganti T, Amer A, Muthusamy N, Jarjoura D, Marsh CB, Carson WE, Byrd JC, Tridandapani S. TLR7/8 Differentially Regulates Fcγ Receptor Expression and Function. Blood. 114: 3594-3594. DOI: 10.1182/Blood.V114.22.3594.3594 |
0.32 |
|
| 2007 |
Valdivia-Arenas MA, Amer A, Henning LN, Wewers MD, Schlesinger LS. Lung infections and innate host defense. Drug Discovery Today: Disease Mechanisms. 4: 73-81. PMID 18592001 DOI: 10.1016/J.Ddmec.2007.10.003 |
0.374 |
|
| 2007 |
Lamkanfi M, Amer A, Kanneganti TD, Muñoz-Planillo R, Chen G, Vandenabeele P, Fortier A, Gros P, Núñez G. The Nod-like receptor family member Naip5/Birc1e restricts Legionella pneumophila growth independently of caspase-1 activation. Journal of Immunology (Baltimore, Md. : 1950). 178: 8022-7. PMID 17548639 DOI: 10.4049/Jimmunol.178.12.8022 |
0.528 |
|
| 2006 |
Kanneganti TD, Body-Malapel M, Amer A, Park JH, Whitfield J, Franchi L, Taraporewala ZF, Miller D, Patton JT, Inohara N, Núñez G. Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA Journal of Biological Chemistry. 281: 36560-36568. PMID 17008311 DOI: 10.1074/Jbc.M607594200 |
0.474 |
|
| 2006 |
Amer A, Franchi L, Kanneganti TD, Body-Malapel M, Ozören N, Brady G, Meshinchi S, Jagirdar R, Gewirtz A, Akira S, Núñez G. Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf. The Journal of Biological Chemistry. 281: 35217-23. PMID 16984919 DOI: 10.1074/Jbc.M604933200 |
0.55 |
|
| 2006 |
Franchi L, McDonald C, Kanneganti TD, Amer A, Núñez G. Nucleotide-binding oligomerization domain-like receptors: intracellular pattern recognition molecules for pathogen detection and host defense. Journal of Immunology (Baltimore, Md. : 1950). 177: 3507-13. PMID 16951308 DOI: 10.4049/Jimmunol.177.6.3507 |
0.375 |
|
| 2006 |
Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozören N, Jagirdar R, Inohara N, Vandenabeele P, Bertin J, Coyle A, Grant EP, Núñez G. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nature Immunology. 7: 576-82. PMID 16648852 DOI: 10.1038/Ni1346 |
0.528 |
|
| 2006 |
Kanneganti TD, Ozören N, Body-Malapel M, Amer A, Park JH, Franchi L, Whitfield J, Barchet W, Colonna M, Vandenabeele P, Bertin J, Coyle A, Grant EP, Akira S, Núñez G. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature. 440: 233-6. PMID 16407888 DOI: 10.1038/Nature04517 |
0.432 |
|
| 2005 |
Amer AO, Byrne BG, Swanson MS. Macrophages rapidly transfer pathogens from lipid raft vacuoles to autophagosomes. Autophagy. 1: 53-8. PMID 16874021 DOI: 10.4161/Auto.1.1.1589 |
0.378 |
|
| 2005 |
Amer AO, Swanson MS. Autophagy is an immediate macrophage response to Legionella pneumophila. Cellular Microbiology. 7: 765-78. PMID 15888080 DOI: 10.1111/J.1462-5822.2005.00509.X |
0.386 |
|
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