Nancy C. Andrews - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Molecular Biology, Genetics, Cell Biology

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tybl E, Gunshin H, Gupta S, Barrientos T, Bonadonna M, Celma Nos F, Palais G, Karim Z, Sanchez M, Andrews NC, Galy B. Control of Systemic Iron Homeostasis by the 3' Iron-Responsive Element of Divalent Metal Transporter 1 in Mice. Hemasphere. 4: e459. PMID 33062942 DOI: 10.1097/HS9.0000000000000459  0.536
2016 Parsons SK, Fleming MD, Nathan DG, Andrews NC. Iron Deficiency Anemia Associated with an Error of Iron Metabolism in Two Siblings: A Thirty Year Follow Up. Hematology (Amsterdam, Netherlands). 1: 65-73. PMID 27406301 DOI: 10.1080/10245332.1996.11746287  0.571
2016 Matak P, Matak A, Moustafa S, Aryal DK, Benner EJ, Wetsel W, Andrews NC. Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 26929359 DOI: 10.1073/Pnas.1519473113  0.586
2015 Barrientos T, Laothamatas I, Koves TR, Soderblom EJ, Bryan M, Moseley MA, Muoio DM, Andrews NC. Metabolic Catastrophe in Mice Lacking Transferrin Receptor in Muscle. Ebiomedicine. 2: 1705-17. PMID 26870796 DOI: 10.1016/J.Ebiom.2015.09.041  0.57
2015 Jabara HH, Boyden SE, Chou J, Ramesh N, Massaad MJ, Benson H, Bainter W, Fraulino D, Rahimov F, Sieff C, Liu ZJ, Alshemmari SH, Al-Ramadi BK, Al-Dhekri H, Arnaout R, ... ... Andrews NC, et al. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency. Nature Genetics. PMID 26642240 DOI: 10.1038/Ng.3465  0.468
2015 Xu W, Barrientos T, Mao L, Rockman HA, Sauve AA, Andrews NC. Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart. Cell Reports. 13: 533-45. PMID 26456827 DOI: 10.1016/J.Celrep.2015.09.023  0.571
2015 Chen AC, Donovan A, Ned-Sykes R, Andrews NC. Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26324903 DOI: 10.1073/Pnas.1511701112  0.651
2015 Andrews NC. Hungry irony Journal of Clinical Investigation. 125: 3422-3423. PMID 26301806 DOI: 10.1172/JCI83193  0.595
2013 Xu W, Barrientos T, Andrews NC. Iron and copper in mitochondrial diseases. Cell Metabolism. 17: 319-28. PMID 23473029 DOI: 10.1016/J.Cmet.2013.02.004  0.323
2012 Hansen JB, Tonnesen MF, Madsen AN, Hagedorn PH, Friberg J, Grunnet LG, Heller RS, Nielsen AØ, Størling J, Baeyens L, Anker-Kitai L, Qvortrup K, Bouwens L, Efrat S, Aalund M, ... Andrews NC, et al. Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic β cell fate in response to cytokines. Cell Metabolism. 16: 449-61. PMID 23000401 DOI: 10.1016/J.Cmet.2012.09.001  0.58
2012 Prince OD, Langdon JM, Layman AJ, Prince IC, Sabogal M, Mak HH, Berger AE, Cheadle C, Chrest FJ, Yu Q, Andrews NC, Xue QL, Civin CI, Walston JD, Roy CN. Late stage erythroid precursor production is impaired in mice with chronic inflammation. Haematologica. 97: 1648-56. PMID 22581006 DOI: 10.3324/Haematol.2011.053397  0.588
2012 Andrews NC. Closing the iron gate New England Journal of Medicine. 366: 376-377. PMID 22276828 DOI: 10.1056/Nejmcibr1112780  0.643
2012 Roberts KA, Abraira VE, Tucker AF, Goodrich LV, Andrews NC. Mutation of Rubie, a novel long non-coding RNA located upstream of Bmp4, causes vestibular malformation in mice. Plos One. 7: e29495. PMID 22253730 DOI: 10.1371/Journal.Pone.0029495  0.362
2012 Stagg DB, Gardenghi S, Rivella S, Andrews NC, Finberg KE. Genetic Loss of Tmprss6 Increases Effective Erythropoiesis in a Mouse Model of β-Thalassemia Blood. 120: 482-482. DOI: 10.1182/Blood.V120.21.482.482  0.779
2011 Andrews NC. An iron-clad role for proteasomal degradation. Cell Metabolism. 14: 281-2. PMID 21907132 DOI: 10.1016/J.Cmet.2011.08.001  0.634
2011 Chen W, Huang FW, de Renshaw TB, Andrews NC. Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis. Blood. 117: 6319-25. PMID 21493799 DOI: 10.1182/Blood-2010-12-327957  0.761
2011 Finberg KE, Whittlesey RL, Andrews NC. Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice. Blood. 117: 4590-9. PMID 21355094 DOI: 10.1182/Blood-2010-10-315507  0.834
2011 Bartnikas TB, Andrews NC, Fleming MD. Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice. Blood. 117: 630-7. PMID 20956801 DOI: 10.1182/Blood-2010-05-287359  0.638
2010 Gardenghi S, Ramos P, Marongiu MF, Melchiori L, Breda L, Guy E, Muirhead K, Rao N, Roy CN, Andrews NC, Nemeth E, Follenzi A, An X, Mohandas N, Ginzburg Y, et al. Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice. The Journal of Clinical Investigation. 120: 4466-77. PMID 21099112 DOI: 10.1172/Jci41717  0.69
2010 Schmidt PJ, Andrews NC, Fleming MD. Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin. Blood. 116: 5679-87. PMID 20837779 DOI: 10.1182/Blood-2010-04-277954  0.603
2010 Andrews NC. Ferrit(in)ing out new mechanisms in iron homeostasis. Cell Metabolism. 12: 203-4. PMID 20816083 DOI: 10.1016/J.Cmet.2010.08.011  0.664
2010 Finberg KE, Whittlesey RL, Fleming MD, Andrews NC. Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis. Blood. 115: 3817-26. PMID 20200349 DOI: 10.1182/Blood-2009-05-224808  0.843
2010 Ferrucci L, Semba RD, Guralnik JM, Ershler WB, Bandinelli S, Patel KV, Sun K, Woodman RC, Andrews NC, Cotter RJ, Ganz T, Nemeth E, Longo DL. Proinflammatory state, hepcidin, and anemia in older persons. Blood. 115: 3810-6. PMID 20081092 DOI: 10.1182/Blood-2009-02-201087  0.558
2010 Wehbe RM, Whittlesey RL, Andrews NC, Finberg KE. The Serine Protease Tmprss6 Regulates Hepcidin Expression, but Its Loss Does Not Cause Systemic Iron Deficiency In the Fetal and Neonatal Periods Blood. 116: 4258-4258. DOI: 10.1182/Blood.V116.21.4258.4258  0.834
2010 Finberg KE, Whittlesey RL, Rivella S, Andrews NC. Tmprss6, An Inhibitor of Hepatic Bmp/Smad Signaling, Is Required for Hepcidin Suppression and Iron Loading In a Mouse Model of β-Thalassemia Blood. 116: 164-164. DOI: 10.1182/Blood.V116.21.164.164  0.818
2010 Gardenghi S, Ramos P, Roy CN, Andrews NC, Nemeth E, An X, Narla M, Ginzburg Y, Rachmilewitz EA, Giardina P, Grady RW, Rivella S. Hepcidin as a Therapeutic Tool to Limit Iron Overload and Improve Anemia In β-Thalassemia Blood. 116: 1009-1009. DOI: 10.1182/Blood.V116.21.1009.1009  0.63
2010 Andrews NC. Ferrit(in)ing out new mechanisms in iron homeostasis Cell Metabolism. 12: 203-204. DOI: 10.1016/j.cmet.2010.08.011  0.599
2010 Andrews NC, Ganz T. The Molecular Basis of Iron Metabolism Molecular Hematology: Third Edition. 169-178. DOI: 10.1002/9781444318531.ch14  0.467
2009 Andrews NC. Genes determining blood cell traits Nature Genetics. 41: 1161-1162. PMID 19862006 DOI: 10.1038/Ng1109-1161  0.419
2009 Andrews NC. ABCs of erythroid mitochondrial iron uptake Proceedings of the National Academy of Sciences of the United States of America. 106: 16012-16013. PMID 19805253 DOI: 10.1073/Pnas.0909137106  0.441
2009 Carlson ES, Tkac I, Magid R, O'Connor MB, Andrews NC, Schallert T, Gunshin H, Georgieff MK, Petryk A. Iron is essential for neuron development and memory function in mouse hippocampus. The Journal of Nutrition. 139: 672-9. PMID 19211831 DOI: 10.3945/Jn.108.096354  0.564
2009 Li JY, Paragas N, Ned RM, Qiu A, Viltard M, Leete T, Drexler IR, Chen X, Sanna-Cherchi S, Mohammed F, Williams D, Lin CS, Schmidt-Ott KM, Andrews NC, Barasch J. Scara5 is a ferritin receptor mediating non-transferrin iron delivery. Developmental Cell. 16: 35-46. PMID 19154717 DOI: 10.1016/J.Devcel.2008.12.002  0.839
2008 Jin J, Desai BN, Navarro B, Donovan A, Andrews NC, Clapham DE. Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis. Science (New York, N.Y.). 322: 756-60. PMID 18974357 DOI: 10.1126/Science.1163493  0.328
2008 Andrews NC. Forging a field: The golden age of iron biology Blood. 112: 219-230. PMID 18606887 DOI: 10.1182/Blood-2007-12-077388  0.582
2008 Zhu BM, McLaughlin SK, Na R, Liu J, Cui Y, Martin C, Kimura A, Robinson GW, Andrews NC, Hennighausen L. Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression. Blood. 112: 2071-80. PMID 18552213 DOI: 10.1182/Blood-2007-12-127480  0.612
2008 Finberg KE, Heeney MM, Campagna DR, Aydinok Y, Pearson HA, Hartman KR, Mayo MM, Samuel SM, Strouse JJ, Markianos K, Andrews NC, Fleming MD. Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA). Nature Genetics. 40: 569-71. PMID 18408718 DOI: 10.1038/Ng.130  0.833
2008 Liu S, Suragani RN, Han A, Zhao W, Andrews NC, Chen JJ. Deficiency of heme-regulated eIF2alpha kinase decreases hepcidin expression and splenic iron in HFE-/- mice. Haematologica. 93: 753-6. PMID 18367482 DOI: 10.3324/Haematol.12175  0.656
2008 Schmidt PJ, Toran PT, Giannetti AM, Bjorkman PJ, Andrews NC. The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression. Cell Metabolism. 7: 205-14. PMID 18316026 DOI: 10.1016/J.Cmet.2007.11.016  0.654
2008 Wrighting DM, Andrews NC. Iron homeostasis and erythropoiesis. Current Topics in Developmental Biology. 82: 141-67. PMID 18282520 DOI: 10.1016/S0070-2153(07)00006-3  0.87
2008 Prince OD, Prince IC, Walston J, Andrews NC, Civin CI, Roy CN. Inhibited Maturation of Ter119+CD71+ Erythroid Precursors in Mice with Chronic Sterile Abscess. Blood. 112: 3844-3844. DOI: 10.1182/Blood.V112.11.3844.3844  0.585
2008 Gardenghi S, Marongiu MF, Muirhead K, Ramos P, Roy CN, Andrews NC, Nemeth E, Follenzi A, Rachmilewitz E, Giardina P, Grady RW, Rivella S. Increased Hepcidin Expression in Mice Affected by β-Thalassemia Reduces Iron Overload with No Effect on Anemia Blood. 112: 128-128. DOI: 10.1182/BLOOD.V112.11.128.128  0.573
2007 Liu S, Suragani RN, Wang F, Han A, Zhao W, Andrews NC, Chen JJ. The function of heme-regulated eIF2alpha kinase in murine iron homeostasis and macrophage maturation. The Journal of Clinical Investigation. 117: 3296-305. PMID 17932563 DOI: 10.1172/Jci32084  0.665
2007 Wang F, Paradkar PN, Custodio AO, McVey Ward D, Fleming MD, Campagna D, Roberts KA, Boyartchuk V, Dietrich WF, Kaplan J, Andrews NC. Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice. Nature Genetics. 39: 1025-32. PMID 17632513 DOI: 10.1038/Ng2059  0.859
2007 Babitt JL, Huang FW, Xia Y, Sidis Y, Andrews NC, Lin HY. Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. The Journal of Clinical Investigation. 117: 1933-9. PMID 17607365 DOI: 10.1172/Jci31342  0.814
2007 Wang F, Lothrop AP, James NG, Griffiths TA, Lambert LA, Leverence R, Kaltashov IA, Andrews NC, MacGillivray RT, Mason AB. A novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydrase. The Biochemical Journal. 406: 85-95. PMID 17511619 DOI: 10.1042/Bj20070384  0.57
2007 Gardenghi S, Marongiu MF, Ramos P, Guy E, Breda L, Chadburn A, Liu Y, Amariglio N, Rechavi G, Rachmilewitz EA, Breuer W, Cabantchik ZI, Wrighting DM, Andrews NC, de Sousa M, et al. Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin. Blood. 109: 5027-35. PMID 17299088 DOI: 10.1182/Blood-2006-09-048868  0.866
2007 Radoshitzky SR, Abraham J, Spiropoulou CF, Kuhn JH, Nguyen D, Li W, Nagel J, Schmidt PJ, Nunberg JH, Andrews NC, Farzan M, Choe H. Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses. Nature. 446: 92-6. PMID 17287727 DOI: 10.1038/Nature05539  0.358
2007 Roy CN, Mak HH, Akpan I, Losyev G, Zurakowski D, Andrews NC. Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammation. Blood. 109: 4038-44. PMID 17218383 DOI: 10.1182/Blood-2006-10-051755  0.643
2007 Andrews NC, Schmidt PJ. Iron homeostasis. Annual Review of Physiology. 69: 69-85. PMID 17014365 DOI: 10.1146/annurev.physiol.69.031905.164337  0.582
2007 Andrews NC. Of mice and iron: Ferroportin disease Blood. 109: 4115. DOI: 10.1182/Blood-2007-02-075739  0.461
2006 Goswami T, Andrews NC. Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing. The Journal of Biological Chemistry. 281: 28494-8. PMID 16893896 DOI: 10.1074/Jbc.C600197200  0.629
2006 Wrighting DM, Andrews NC. Interleukin-6 induces hepcidin expression through STAT3. Blood. 108: 3204-9. PMID 16835372 DOI: 10.1182/Blood-2006-06-027631  0.841
2006 Babitt JL, Huang FW, Wrighting DM, Xia Y, Sidis Y, Samad TA, Campagna JA, Chung RT, Schneyer AL, Woolf CJ, Andrews NC, Lin HY. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nature Genetics. 38: 531-9. PMID 16604073 DOI: 10.1038/Ng1777  0.842
2006 Donovan A, Roy CN, Andrews NC. The ins and outs of iron homeostasis. Physiology (Bethesda, Md.). 21: 115-23. PMID 16565477 DOI: 10.1152/Physiol.00052.2005  0.648
2006 Viatte L, Nicolas G, Lou DQ, Bennoun M, Lesbordes-Brion JC, Canonne-Hergaux F, Schönig K, Bujard H, Kahn A, Andrews NC, Vaulont S. Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice. Blood. 107: 2952-8. PMID 16339398 DOI: 10.1182/Blood-2005-10-4071  0.696
2006 Schmidt PJ, Huang FW, Wrighting DM, Toran PT, Andrews NC. Hepcidin Expression Is Regulated by a Complex of Hemochromatosis-Associated Proteins. Blood. 108: 267-267. DOI: 10.1182/Blood.V108.11.267.267  0.842
2006 Andrews NC. Iron Absorption Physiology of the Gastrointestinal Tract. 2: 1983-1992. DOI: 10.1016/B978-012088394-3/50081-7  0.559
2005 Adams BD, Lazova R, Andrews NC, Milstone LM. Iron in skin of mice with three etiologies of systemic iron overload. The Journal of Investigative Dermatology. 125: 1200-5. PMID 16354190 DOI: 10.1111/J.0022-202X.2005.23949.X  0.66
2005 Andrews NC. Understanding heme transport New England Journal of Medicine. 353: 2508-2509. PMID 16339100 DOI: 10.1056/Nejmcibr053987  0.354
2005 Lim JE, Jin O, Bennett C, Morgan K, Wang F, Trenor CC, Fleming MD, Andrews NC. A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice. Nature Genetics. 37: 1270-3. PMID 16227995 DOI: 10.1038/Ng1659  0.866
2005 Gunshin H, Jin J, Fujiwara Y, Andrews NC, Mims M, Prchal J. Analysis of the E399D mutation in SLC11A2 (mutiple letters) Blood. 106: 2221-2222. PMID 16140868 DOI: 10.1182/Blood-2005-03-1192  0.602
2005 Huang FW, Pinkus JL, Pinkus GS, Fleming MD, Andrews NC. A mouse model of juvenile hemochromatosis. The Journal of Clinical Investigation. 115: 2187-91. PMID 16075059 DOI: 10.1172/Jci25049  0.83
2005 Donovan A, Lima CA, Pinkus JL, Pinkus GS, Zon LI, Robine S, Andrews NC. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metabolism. 1: 191-200. PMID 16054062 DOI: 10.1016/J.Cmet.2005.01.003  0.683
2005 Gunshin H, Starr CN, Direnzo C, Fleming MD, Jin J, Greer EL, Sellers VM, Galica SM, Andrews NC. Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice. Blood. 106: 2879-83. PMID 15961514 DOI: 10.1182/Blood-2005-02-0716  0.674
2005 Gunshin H, Fujiwara Y, Custodio AO, Direnzo C, Robine S, Andrews NC. Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver. The Journal of Clinical Investigation. 115: 1258-66. PMID 15849611 DOI: 10.1172/Jci24356  0.863
2005 Andrews NC. Molecular control of iron metabolism Best Practice and Research: Clinical Haematology. 18: 159-169. PMID 15737882 DOI: 10.1016/J.Beha.2004.10.004  0.587
2005 Roy CN, Andrews NC. Anemia of inflammation: the hepcidin link. Current Opinion in Hematology. 12: 107-11. PMID 15725899 DOI: 10.1097/00062752-200503000-00001  0.473
2005 Tolosano E, Fagoonee S, Garuti C, Valli L, Andrews NC, Altruda F, Pietrangelo A. Haptoglobin modifies the hemochromatosis phenotype in mice. Blood. 105: 3353-5. PMID 15613548 DOI: 10.1182/Blood-2004-07-2814  0.647
2005 Lim JE, Morgan K, Wang F, Fleming MD, Andrews NC. A Mutation in Sec15l1 Disrupts the Transferrin Cycle and Causes Anemia in Hemoglobin Deficit (hbd) Mice. Blood. 106: 513-513. DOI: 10.1182/Blood.V106.11.513.513  0.865
2005 Huang FW, Babitt JL, Wrighting DM, Samad TA, Xia Y, Sidis Y, Campagna JA, Chung RT, Schneyer AL, Woolf CJ, Andrews NC, Lin HY. Hemojuvelin Acts as a Bone Morphogenetic Protein Co-Receptor To Regulate Hepcidin Expression. Blood. 106: 511-511. DOI: 10.1182/Blood.V106.11.511.511  0.832
2004 Andrews NC. Pathophysiologic mechanisms of anemia of chronic disease Postgraduate Medicine. 116: 17-22. PMID 19667680 DOI: 10.3810/Pgm.11.2004.Suppl36.250  0.466
2004 Andrews NC. Probing the iron pool. Focus on "Detection of intracellular iron by its regulatory effect" American Journal of Physiology - Cell Physiology. 287. PMID 15525686 DOI: 10.1152/Ajpcell.00435.2004  0.659
2004 Heeney MM, Andrews NC. Iron homeostasis and inherited iron overload disorders: an overview. Hematology/Oncology Clinics of North America. 18: 1379-403, ix. PMID 15511621 DOI: 10.1016/J.Hoc.2004.06.018  0.671
2004 Donovan A, Andrews NC. The molecular regulation of iron metabolism Hematology Journal. 5: 373-380. PMID 15448662 DOI: 10.1038/Sj.Thj.6200540  0.664
2004 Macedo MF, de Sousa M, Ned RM, Mascarenhas C, Andrews NC, Correia-Neves M. Transferrin is required for early T-cell differentiation. Immunology. 112: 543-9. PMID 15270724 DOI: 10.1111/J.1365-2567.2004.01915.X  0.755
2004 Huang FW, Rubio-Aliaga I, Kushner JP, Andrews NC, Fleming MD. Identification of a novel mutation (C321X) in HJV. Blood. 104: 2176-7. PMID 15138164 DOI: 10.1182/Blood-2004-01-0400  0.725
2004 Andrews NC. Anemia of inflammation: The cytokine-hepcidin link Journal of Clinical Investigation. 113: 1251-1253. PMID 15124013 DOI: 10.1172/Jci21441  0.396
2004 Hentze MW, Muckenthaler MU, Andrews NC. Balancing acts: molecular control of mammalian iron metabolism. Cell. 117: 285-97. PMID 15109490 DOI: 10.1016/S0092-8674(04)00343-5  0.654
2004 Roy CN, Custodio AO, de Graaf J, Schneider S, Akpan I, Montross LK, Sanchez M, Gaudino A, Hentze MW, Andrews NC, Muckenthaler MU. An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice. Nature Genetics. 36: 481-5. PMID 15098034 DOI: 10.1038/Ng1350  0.862
2004 Derjuga A, Gourley TS, Holm TM, Heng HH, Shivdasani RA, Ahmed R, Andrews NC, Blank V. Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus. Molecular and Cellular Biology. 24: 3286-94. PMID 15060151 DOI: 10.1128/Mcb.24.8.3286-3294.2004  0.392
2004 Xu H, Jin J, DeFelice LJ, Andrews NC, Clapham DE. A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway. Plos Biology. 2: E50. PMID 15024413 DOI: 10.1371/Journal.Pbio.0020050  0.556
2004 Miranda CJ, Makui H, Andrews NC, Santos MM. Contributions of beta2-microglobulin-dependent molecules and lymphocytes to iron regulation: insights from HfeRag1(-/-) and beta2mRag1(-/-) double knock-out mice. Blood. 103: 2847-9. PMID 14656877 DOI: 10.1182/Blood-2003-09-3300  0.644
2004 Nicolas G, Andrews NC, Kahn A, Vaulont S. Hepcidin, a candidate modifier of the hemochromatosis phenotype in mice. Blood. 103: 2841-3. PMID 14656876 DOI: 10.1182/Blood-2003-09-3358  0.652
2004 Gunshin H, Fujiwara Y, Custodio AO, DiRenzo C, Robine S, Andrews NC. Iron Metabolism in the Mice with Targeted Mutations of the DMT1 Gene . Blood. 104: 50-50. DOI: 10.1182/Blood.V104.11.50.50  0.845
2004 Semrin G, Andrews NC, Bousvaros A, Grand R, Zholudev A, Saunders A, Weinstien D. P0726 IMPAIRED INTESTINAL IRON ABSORPTION IN CROHN???S DISEASE CORRELATES WITH DISEASE ACTIVITY AND INFLAMMATORY CYTOKINES Journal of Pediatric Gastroenterology and Nutrition. 39: S333. DOI: 10.1097/00005176-200406001-00850  0.328
2003 Ned RM, Swat W, Andrews NC. Transferrin receptor 1 is differentially required in lymphocyte development. Blood. 102: 3711-8. PMID 12881306 DOI: 10.1182/Blood-2003-04-1086  0.794
2003 Santos MM, Miranda CJ, Levy JE, Montross LK, Cossée M, Sequeiros J, Andrews N, Koenig M, Pandolfo M. Iron metabolism in mice with partial frataxin deficiency The Cerebellum. 2: 146-153. PMID 12880182 DOI: 10.1080/14734220309408  0.676
2003 Miranda CJ, Makui H, Soares RJ, Bilodeau M, Mui J, Vali H, Bertrand R, Andrews NC, Santos MM. Hfe deficiency increases susceptibility to cardiotoxicity and exacerbates changes in iron metabolism induced by doxorubicin. Blood. 102: 2574-80. PMID 12805055 DOI: 10.1182/Blood-2003-03-0869  0.628
2003 Muckenthaler M, Roy CN, Custodio AO, Miñana B, deGraaf J, Montross LK, Andrews NC, Hentze MW. Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis. Nature Genetics. 34: 102-7. PMID 12704390 DOI: 10.1038/Ng1152  0.863
2003 Nicolas G, Viatte L, Lou DQ, Bennoun M, Beaumont C, Kahn A, Andrews NC, Vaulont S. Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis. Nature Genetics. 34: 97-101. PMID 12704388 DOI: 10.1038/Ng1150  0.697
2003 Roy CN, Weinstein DA, Andrews NC. 2002 E. Mead Johnson Award for Research in Pediatrics Lecture: the molecular biology of the anemia of chronic disease: a hypothesis. Pediatric Research. 53: 507-12. PMID 12595602 DOI: 10.1203/01.Pdr.0000049513.67410.2D  0.462
2003 Andrews NC. Animal models of hereditary iron transport disorders Advances in Experimental Medicine and Biology. 509: 1-17. PMID 12572986 DOI: 10.1007/978-1-4615-0593-8_1  0.632
2003 Andrews NC, Roy CN. Forging iron links Blood. 101: 2450-2450. DOI: 10.1182/Blood-2003-01-0278  0.662
2002 Weinstein DA, Roy CN, Fleming MD, Loda MF, Wolfsdorf JI, Andrews NC. Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood. 100: 3776-81. PMID 12393428 DOI: 10.1182/Blood-2002-04-1260  0.615
2002 Andrews NC. A genetic view of iron homeostasis Seminars in Hematology. 39: 227-234. PMID 12382197 DOI: 10.1053/Shem.2002.35632  0.658
2002 Ajioka RS, Levy JE, Andrews NC, Kushner JP. Regulation of iron absorption in Hfe mutant mice. Blood. 100: 1465-9. PMID 12149232 DOI: 10.1182/Blood-2001-11-0037  0.686
2002 Andrews NC. Metal transporters and disease Current Opinion in Chemical Biology. 6: 181-186. PMID 12039002 DOI: 10.1016/S1367-5931(02)00307-1  0.378
2002 Holm TM, Braun A, Trigatti BL, Brugnara C, Sakamoto M, Krieger M, Andrews NC. Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI. Blood. 99: 1817-24. PMID 11861300 DOI: 10.1182/Blood.V99.5.1817  0.308
2002 Roy CN, Andrews NC. Recent advances in disorders of iron metabolism: mutations, mechanisms and modifiers. Human Molecular Genetics. 10: 2181-6. PMID 11673399 DOI: 10.1093/Hmg/10.20.2181  0.66
2001 Gunshin H, Allerson CR, Polycarpou-Schwarz M, Rofts A, Rogers JT, Kishi F, Hentze MW, Rouault TA, Andrews NC, Hediger MA. Iron-dependent regulation of the divalent metal ion transporter. Febs Letters. 509: 309-16. PMID 11741608 DOI: 10.1016/S0014-5793(01)03189-1  0.614
2001 Montosi G, Donovan A, Totaro A, Garuti C, Pignatti E, Cassanelli S, Trenor CC, Gasparini P, Andrews NC, Pietrangelo A. Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. The Journal of Clinical Investigation. 108: 619-23. PMID 11518736 DOI: 10.1172/Jci13468  0.612
2001 Andrews NC. Mining copper transport genes Proceedings of the National Academy of Sciences of the United States of America. 98: 6543-6545. PMID 11390990 DOI: 10.1073/Pnas.131192498  0.329
2001 Knutson MD, Levy JE, Andrews NC, Wessling-Resnick M. Expression of stimulator of Fe transport is not enhanced in Hfe knockout mice. The Journal of Nutrition. 131: 1459-64. PMID 11340100 DOI: 10.1093/Jn/131.5.1459  0.616
2001 Fleming MD, Campagna DR, Haslett JN, Trenor CC, Andrews NC. A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice. Genes & Development. 15: 652-7. PMID 11274051 DOI: 10.1101/Gad.873001  0.517
2001 Sinclair PR, Gorman N, Walton HS, Bement WJ, Sinclair JF, Gerhard GS, Szakacs JG, Andrews NC, Levy JE. Uroporphyria in Hfe mutant mice given 5-aminolevulinate: a new model of Fe-mediated porphyria cutanea tarda. Hepatology (Baltimore, Md.). 33: 406-12. PMID 11172342 DOI: 10.1053/Jhep.2001.21409  0.605
2001 Canonne-Hergaux F, Levy JE, Fleming MD, Montross LK, Andrews NC, Gros P. Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders. Blood. 97: 1138-40. PMID 11159549 DOI: 10.1182/Blood.V97.4.1138  0.709
2001 Andrews NC. Ferreting out the dynamics of ferritin expression Blood. 98: 503-504. DOI: 10.1182/Blood.V98.3.503B  0.431
2001 Phillips JD, Jackson LK, Bunting M, Franklin MR, Thomas KR, Levy JE, Andrews NC, Kushner JP. A mouse model of familial porphyria cutanea tarda Proceedings of the National Academy of Sciences. 98: 259-264. DOI: 10.1073/Pnas.98.1.259  0.412
2000 Andrews NC. Iron metabolism: Iron deficiency and iron overload Annual Review of Genomics and Human Genetics. 1: 75-98. PMID 11701625 DOI: 10.1146/Annurev.Genom.1.1.75  0.666
2000 Andrews NC. Iron homeostasis: Insights from genetics and animal models Nature Reviews Genetics. 1: 208-217. PMID 11252750 DOI: 10.1038/35042073  0.661
2000 Andrews NC. Inherited iron overload disorders Current Opinion in Pediatrics. 12: 596-602. PMID 11106282 DOI: 10.1097/00008480-200012000-00015  0.636
2000 West AP, Bennett MJ, Sellers VM, Andrews NC, Enns CA, Bjorkman PJ. Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE. The Journal of Biological Chemistry. 275: 38135-8. PMID 11027676 DOI: 10.1074/Jbc.C000664200  0.554
2000 Andrews NC. Intestinal iron absorption: Current concepts circa 2000 Digestive and Liver Disease. 32: 56-61. PMID 10975756 DOI: 10.1016/S1590-8658(00)80045-6  0.655
2000 Levy JE, Montross LK, Andrews NC. Genes that modify the hemochromatosis phenotype in mice. The Journal of Clinical Investigation. 105: 1209-16. PMID 10791995 DOI: 10.1172/Jci9635  0.701
2000 Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, ... ... Andrews NC, et al. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature. 403: 776-81. PMID 10693807 DOI: 10.1038/35001596  0.673
2000 Trenor CC, Campagna DR, Sellers VM, Andrews NC, Fleming MD. The molecular defect in hypotransferrinemic mice Blood. 96: 1113-1118. DOI: 10.1182/Blood.V96.3.1113.015K03_1113_1118  0.586
2000 Trenor CC, Campagna DR, Sellers VM, Andrews NC, Fleming MD. The molecular defect in hypotransferrinemic mice Blood. 96: 1113-1118. DOI: 10.1182/blood.v96.3.1113  0.506
2000 Canonne-Hergaux F, Fleming MD, Levy JE, Gauthier S, Ralph T, Picard V, Andrews NC, Gros P. The Nramp2/DMT1 iron transporter is induced in the duodenum of microcytic anemia mk mice but is not properly targeted to the intestinal brush border. Blood. 96: 3964-3970. DOI: 10.1182/Blood.V96.12.3964.H8003964_3964_3970  0.576
2000 Andrews NC. Iron metabolism and absorption Reviews in Clinical and Experimental Hematology. 4: 283-301. DOI: 10.1046/J.1468-0734.2000.00021.X  0.645
1999 Andrews NC. Disorders of iron metabolism New England Journal of Medicine. 341: 1986-1995. PMID 10607817 DOI: 10.1056/Nejm199912233412607  0.608
1999 Andrews NC. The iron transporter DMT1 International Journal of Biochemistry and Cell Biology. 31: 991-994. PMID 10582331 DOI: 10.1016/S1357-2725(99)00065-5  0.655
1999 Andrews NC, Fleming MD. Commentary on: ferrokinetics in the syndrome of familial hypoferremic microcytic anemia with iron malabsorption. Journal of Pediatric Hematology/Oncology. 21: 353-5. PMID 10524446 DOI: 10.1097/00043426-199909000-00004  0.449
1999 Andrews NC, Fleming MD, Gunshin H. Iron transport across biologic membranes. Nutrition Reviews. 57: 114-23. PMID 10228348 DOI: 10.1111/J.1753-4887.1999.Tb06934.X  0.614
1999 Levy JE, Jin O, Fujiwara Y, Kuo F, Andrews N. Transferrin receptor is necessary for development of erythrocytes and the nervous system Nature Genetics. 21: 396-399. PMID 10192390 DOI: 10.1038/7727  0.68
1999 Andrews NC, Fleming MD, Levy JE. Molecular insights into mechanisms of iron transport. Current Opinion in Hematology. 6: 61-4. PMID 10088633 DOI: 10.1097/00062752-199903000-00001  0.64
1999 Levy JE, Montross LK, Cohen DE, Fleming MD, Andrews NC. The C282Y Mutation Causing Hereditary Hemochromatosis Does Not Produce a Null Allele Blood. 94: 9-11. DOI: 10.1182/Blood.V94.1.9.413A43_9_11  0.447
1998 Fleming MD, Andrews NC. Mammalian iron transport: an unexpected link between metal homeostasis and host defense. The Journal of Laboratory and Clinical Medicine. 132: 464-8. PMID 9851735 DOI: 10.1016/S0022-2143(98)90123-8  0.637
1998 Andrews NC. Molecules in focus the NF-E2 transcription factor International Journal of Biochemistry and Cell Biology. 30: 429-432. PMID 9675875 DOI: 10.1016/S1357-2725(97)00135-0  0.321
1998 Fleming MD, Romano MA, Su MA, Garrick LM, Garrick MD, Andrews NC. Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proceedings of the National Academy of Sciences of the United States of America. 95: 1148-53. PMID 9448300 DOI: 10.1073/Pnas.95.3.1148  0.556
1998 Su MA, Fleming MD, Trenor CC, Andrews NC. Nramp2 Transports Ferrous Iron, and is Defective in mk Mice and b Rats • 800 Pediatric Research. 43: 139-139. DOI: 10.1203/00006450-199804001-00821  0.538
1998 Su MA, Trenor CC, Fleming JC, Fleming MD, Andrews NC. The G185R Mutation Disrupts Function of the Iron Transporter Nramp2 Blood. 92: 2157-2163. DOI: 10.1182/Blood.V92.6.2157.418K16_2157_2163  0.62
1998 Andrews NC, Levy JE. Iron Is Hot: An Update on the Pathophysiology of Hemochromatosis Blood. 92: 1845-1851. DOI: 10.1182/Blood.V92.6.1845.418K35_1845_1851  0.656
1998 Andrews NC, Levy JE. Iron Is Hot: An Update on the Pathophysiology of Hemochromatosis Blood. 92: 1845-1851. DOI: 10.1182/BLOOD.V92.6.1845.418K35_1845_1851  0.59
1997 Fleming MD, Trenor CC, Su MA, Foernzler D, Beier DR, Dietrich WF, Andrews NC. Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene. Nature Genetics. 16: 383-6. PMID 9241278 DOI: 10.1038/Ng0897-383  0.659
1994 Lim KC, Ishihara H, Riddle RD, Yang Z, Andrews N, Yamamoto M, Engel JD. Structure and regulation of the chicken erythroid δ-aminolevulinate synthase gene Nucleic Acids Research. 22: 1226-1233. PMID 8165137 DOI: 10.1093/Nar/22.7.1226  0.396
1994 Peters LL, Andrews NC, Eicher EM, Davidson MB, Orkin SH, Lux SE. Correction: Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2 Nature. 371: 358-358. DOI: 10.1038/371358B0  0.387
1993 Peters LL, Andrews NC, Eicher EM, Davidson MB, Orkin SH, Lux SE. Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2. Nature. 362: 768-770. PMID 8469289 DOI: 10.1038/362768A0  0.417
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