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Gerard Evan - Publications

Affiliations: 
Biomedical Sciences University of California, San Francisco, San Francisco, CA 
Area:
Neuroscience Biology
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61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Dhillon P, Evan G. In conversation with Gerard Evan. The Febs Journal. 286: 4824-4831. PMID 31860788 DOI: 10.1111/Febs.15121  0.375
2019 Propper D, Han H, Hoff DV, Borazanci E, Reya T, Ghergurovich J, Pshenichnaya I, Antal C, Condjella R, Sharma S, O'Dwyer P, Littlewood T, Patel H, Saluja A, Velagapudi M, ... ... Evan G, et al. Abstract CT165: Phase II open label trial of minnelide™ in patients with chemotherapy refractory metastatic pancreatic cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Ct165  0.354
2017 Azzarelli R, Hurley C, Sznurkowska MK, Rulands S, Hardwick L, Gamper I, Ali F, McCracken L, Hindley C, McDuff F, Nestorowa S, Kemp R, Jones K, Göttgens B, Huch M, ... Evan G, et al. Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation. Developmental Cell. PMID 28457793 DOI: 10.1016/J.Devcel.2017.04.004  0.332
2016 Jung LA, Gebhardt A, Koelmel W, Ade CP, Walz S, Kuper J, von Eyss B, Letschert S, Redel C, d'Artista L, Biankin A, Zender L, Sauer M, Wolf E, Evan G, et al. OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors. Oncogene. PMID 27748763 DOI: 10.1038/Onc.2016.354  0.36
2015 Brindle NR, Joyce JA, Rostker F, Lawlor ER, Swigart-Brown L, Evan G, Hanahan D, Shchors K. Deficiency for the cysteine protease cathepsin L impairs Myc-induced tumorigenesis in a mouse model of pancreatic neuroendocrine cancer. Plos One. 10: e0120348. PMID 25927437 DOI: 10.1371/Journal.Pone.0120348  0.307
2015 Correia L, Farah H, Rassl D, Rintoul R, Sethi T, Littlewood T, Evan G, McCaughan F. S102 SOX2 initiates carcinogenesis in a novel organotypic model of bronchial dysplasia Thorax. 70. DOI: 10.1136/Thoraxjnl-2015-207770.108  0.33
2014 Muthalagu N, Junttila MR, Wiese KE, Wolf E, Morton J, Bauer B, Evan GI, Eilers M, Murphy DJ. BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues. Cell Reports. 8: 1347-53. PMID 25176652 DOI: 10.1016/J.Celrep.2014.07.057  0.331
2014 Grayson AR, Walsh EM, Cameron MJ, Godec J, Ashworth T, Ambrose JM, Aserlind AB, Wang H, Evan GI, Kluk MJ, Bradner JE, Aster JC, French CA. MYC, a downstream target of BRD-NUT, is necessary and sufficient for the blockade of differentiation in NUT midline carcinoma Oncogene. 33: 1736-1742. PMID 23604113 DOI: 10.1038/Onc.2013.126  0.384
2013 Farkas C, Martins CP, Escobar D, Hepp MI, Castro AF, Evan G, Gutiérrez JL, Warren R, Donner DB, Pincheira R. Wild type p53 transcriptionally represses the SALL2 transcription factor under genotoxic stress. Plos One. 8: e73817. PMID 24040083 DOI: 10.1371/Journal.Pone.0073817  0.337
2013 Walsh EM, Grayson AR, Cameron MJ, Godec J, Ashworth T, Aserlind AB, Wang H, Evan G, Kluk MJ, Bradner JE, Aster JC, French CA. Abstract B39: MYC, a downstream target of BRD-NUT, is necessary and sufficient for the blockade of differentiation in NUT midline carcinoma Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-B39  0.389
2012 Evan G. Cancer. Taking a back door to target Myc. Science (New York, N.Y.). 335: 293-4. PMID 22267799 DOI: 10.1126/Science.1217819  0.415
2010 Soucek L, Evan GI. The ups and downs of Myc biology. Current Opinion in Genetics & Development. 20: 91-5. PMID 19962879 DOI: 10.1016/j.gde.2009.11.001  0.334
2009 Radziszewska A, Schroer SA, Choi D, Tajmir P, Radulovich N, Ho JC, Wang L, Liadis N, Hakem R, Tsao MS, Penn LZ, Evan GI, Woo M. Absence of caspase-3 protects pancreatic {beta}-cells from c-Myc-induced apoptosis without leading to tumor formation. The Journal of Biological Chemistry. 284: 10947-56. PMID 19213729 DOI: 10.1074/Jbc.M806960200  0.324
2007 Abayasiriwardana KS, Barbone D, Kim KU, Vivo C, Lee KK, Dansen TB, Hunt AE, Evan GI, Broaddus VC. Malignant mesothelioma cells are rapidly sensitized to TRAIL-induced apoptosis by low-dose anisomycin via Bim. Molecular Cancer Therapeutics. 6: 2766-76. PMID 17938269 DOI: 10.1158/1535-7163.MCT-07-0278  0.305
2007 Amaravadi RK, Yu D, Lum JJ, Bui T, Christophorou MA, Evan GI, Thomas-Tikhonenko A, Thompson CB. Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. The Journal of Clinical Investigation. 117: 326-36. PMID 17235397 DOI: 10.1172/Jci28833  0.309
2006 Flores I, Evan G, Blasco MA. Genetic analysis of myc and telomerase interactions in vivo. Molecular and Cellular Biology. 26: 6130-8. PMID 16880523 DOI: 10.1128/Mcb.00543-06  0.317
2006 Dansen TB, Whitfield J, Rostker F, Brown-Swigart L, Evan GI. Specific requirement for Bax, not Bak, in Myc-induced apoptosis and tumor suppression in vivo. The Journal of Biological Chemistry. 281: 10890-5. PMID 16464852 DOI: 10.1074/jbc.M513655200  0.307
2004 Lowe SW, Cepero E, Evan G. Intrinsic tumour suppression. Nature. 432: 307-15. PMID 15549092 DOI: 10.1038/Nature03098  0.352
2004 Vyas S, Juin P, Hancock D, Suzuki Y, Takahashi R, Triller A, Evan G. Differentiation-dependent sensitivity to apoptogenic factors in PC12 cells. The Journal of Biological Chemistry. 279: 30983-93. PMID 15133027 DOI: 10.1074/Jbc.M400692200  0.423
2004 Murphy DJ, Swigart LB, Israel MA, Evan GI. Id2 is dispensable for Myc-induced epidermal neoplasia. Molecular and Cellular Biology. 24: 2083-90. PMID 14966287 DOI: 10.1128/Mcb.24.5.2083-2090.2004  0.322
2004 Werb Z, Evan G. Oncogenes and cell proliferation: Maintenance of genome integrity, tumor stem cells, and the somatic microenvironment Current Opinion in Genetics and Development. 14: 1-3. DOI: 10.1016/J.Gde.2003.12.004  0.306
2003 Kanazawa S, Soucek L, Evan G, Okamoto T, Peterlin BM. c-Myc recruits P-TEFb for transcription, cellular proliferation and apoptosis. Oncogene. 22: 5707-11. PMID 12944920 DOI: 10.1038/Sj.Onc.1206800  0.388
2003 Iaccarino I, Hancock D, Evan G, Downward J. c-Myc induces cytochrome c release in Rat1 fibroblasts by increasing outer mitochondrial membrane permeability in a Bid-dependent manner. Cell Death & Differentiation. 10: 599-608. PMID 12728258 DOI: 10.1038/Sj.Cdd.4401211  0.374
2003 Moreau C, Cartron PF, Hunt A, Meflah K, Green DR, Evan G, Vallette FM, Juin P. Minimal BH3 peptides promote cell death by antagonizing anti-apoptotic proteins. The Journal of Biological Chemistry. 278: 19426-35. PMID 12642586 DOI: 10.1074/Jbc.M209472200  0.341
2002 Pelengaris S, Khan M, Evan G. c-MYC: more than just a matter of life and death. Nature Reviews. Cancer. 2: 764-76. PMID 12360279 DOI: 10.1038/Nrc904  0.369
2002 Vyas S, Biguet NF, Michel PP, Monaco L, Foulkes NS, Evan GI, Sassone-Corsi P, Agid Y. Molecular mechanisms of neuronal cell death: implications for nuclear factors responding to cAMP and phorbol esters. Molecular and Cellular Neurosciences. 21: 1-14. PMID 12359147 DOI: 10.1006/mcne.2002.1170  0.323
2002 Klefstrom J, Verschuren EW, Evan G. c-Myc augments the apoptotic activity of cytosolic death receptor signaling proteins by engaging the mitochondrial apoptotic pathway. The Journal of Biological Chemistry. 277: 43224-32. PMID 12202489 DOI: 10.1074/Jbc.M206967200  0.406
2002 Juin P, Hunt A, Littlewood T, Griffiths B, Swigart LB, Korsmeyer S, Evan G. c-Myc functionally cooperates with Bax to induce apoptosis. Molecular and Cellular Biology. 22: 6158-69. PMID 12167710 DOI: 10.1128/Mcb.22.17.6158-6169.2002  0.397
2002 Soucek L, Evan G. Myc-Is this the oncogene from Hell? Cancer Cell. 1: 406-8. PMID 12124167 DOI: 10.1016/S1535-6108(02)00077-6  0.322
2002 You Z, Saims D, Chen S, Zhang Z, Guttridge DC, Guan KL, MacDougald OA, Brown AM, Evan G, Kitajewski J, Wang CY. Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis. The Journal of Cell Biology. 157: 429-40. PMID 11980918 DOI: 10.1083/Jcb.200201110  0.399
2002 Zornig M, Hueber AO, Baum W, Evan G. Apoptosis regulators and their role in tumorigenesis. American Journal of Ophthalmology. 133: 301-302. DOI: 10.1016/S0002-9394(01)01388-5  0.353
2001 Evan G. The Relevance of Oncogene-Induced Apoptosis in Cancer. Thescientificworldjournal. 1: 89. PMID 30147559 DOI: 10.1100/Tsw.2001.206  0.445
2001 Zörnig M, Hueber A, Baum W, Evan G. Apoptosis regulators and their role in tumorigenesis. Biochimica Et Biophysica Acta. 1551: F1-37. PMID 11591448 DOI: 10.1016/S0304-419X(01)00031-2  0.384
2001 Hunt A, Evan G. Till Death Us Do Part Science. 293: 1784-1785. DOI: 10.1126/Science.11546862  0.339
2001 Evan G. Oncogenes, apoptosis and cancer, with special emphasis on p53 and c-Myc Biochemical Society Transactions. 29. DOI: 10.1042/Bst029A094C  0.392
2000 Lindsten T, Ross AJ, King A, Zong WX, Rathmell JC, Shiels HA, Ulrich E, Waymire KG, Mahar P, Frauwirth K, Chen Y, Wei M, Eng VM, Adelman DM, Simon MC, ... ... Evan G, et al. The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. Molecular Cell. 6: 1389-99. PMID 11163212 DOI: 10.1016/S1097-2765(00)00136-2  0.307
2000 Meier P, Finch A, Evan G. Apoptosis in development Nature. 407: 796-801. PMID 11048731 DOI: 10.1038/35037734  0.343
2000 Juin P, Evan G. Caspase 8: the killer you can't live without. Nature Medicine. 6: 498-500. PMID 10802696 DOI: 10.1038/74966  0.405
2000 Hueber AO, Zörnig M, Bernard AM, Chautan M, Evan G. A dominant negative Fas-associated death domain protein mutant inhibits proliferation and leads to impaired calcium mobilization in both T-cells and fibroblasts. The Journal of Biological Chemistry. 275: 10453-62. PMID 10744735 DOI: 10.1074/Jbc.275.14.10453  0.379
2000 Blyth K, Stewart M, Bell M, James C, Evan G, Neil JC, Cameron ER. Sensitivity to myc-induced apoptosis is retained in spontaneous and transplanted lymphomas of CD2-mycERTM mice Oncogene. 19: 773-782. PMID 10698495 DOI: 10.1038/Sj.Onc.1203321  0.363
2000 Evan G. Using Animal Models to Study Apoptosis and Cancer Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A012C  0.34
2000 Diffley JFX, Evan G. Oncogenes and cell proliferation. Cell cycle, genome integrity and cancer - A millennial view. Editorial overview Current Opinion in Genetics and Development. 10: 13-16. DOI: 10.1016/S0959-437X(99)00053-2  0.342
1999 Juin P, Hueber A, Littlewood T, Evan G. c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release Genes & Development. 13: 1367-1381. PMID 10364155 DOI: 10.1101/Gad.13.11.1367  0.383
1999 Pelengaris S, Littlewood T, Khan M, Elia G, Evan G. Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion. Molecular Cell. 3: 565-577. PMID 10360173 DOI: 10.1016/S1097-2765(00)80350-0  0.384
1998 Meier P, Evan G. Dying like flies Cell. 95: 295-298. PMID 9814699 DOI: 10.1016/S0092-8674(00)81760-2  0.347
1998 Evan G, Littlewood T. A Matter of Life and Cell Death Science. 281: 1317-1322. PMID 9721090 DOI: 10.1126/Science.281.5381.1317  0.387
1998 Zörnig M, Hueber A, Evan G. p53-dependent impairment of T-cell proliferation in FADD dominant-negative transgenic mice Current Biology. 8: 467-470. PMID 9550704 DOI: 10.1016/S0960-9822(98)70182-4  0.376
1998 Ulrich E, Duwel A, Kauffmann-Zeh A, Gilbert C, Lyon D, Rudkin B, Evan G, Martin-Zanca D. Specific TrkA survival signals interfere with different apoptotic pathways Oncogene. 16: 825-832. PMID 9484773 DOI: 10.1038/Sj.Onc.1201842  0.38
1997 Evan G. Cancer--a matter of life and cell death. International Journal of Cancer. 71: 709-711. PMID 9180133 DOI: 10.1002/(Sici)1097-0215(19970529)71:5<709::Aid-Ijc2>3.0.Co;2-V  0.331
1997 Ink B, Zörnig M, Baum B, Hajibagheri N, James C, Chittenden T, Evan G. Human Bak induces cell death in Schizosaccharomyces pombe with morphological changes similar to those with apoptosis in mammalian cells. Molecular and Cellular Biology. 17: 2468-74. PMID 9111315 DOI: 10.1128/Mcb.17.5.2468  0.404
1997 Kauffmann-Zeh A, Rodriguez-Viciana P, Ulrich E, Gilbert C, Coffer P, Downward J, Evan G. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB Nature. 385: 544-548. PMID 9020362 DOI: 10.1038/385544A0  0.37
1996 Littlewood T, McCarthy N, Whyte M, Pelengaris S, James C, Evan G. Controllable genetic manipulation of apoptosis of cells in culture. Cytotechnology. 22: 157-167. PMID 22358926 DOI: 10.1007/Bf00353935  0.459
1996 Zoernig M, Ink B, Baum B, Evan G. Induced Expression Of The Human Bcl-2 Homologue Bak In S. Pombe Leads To Growth Arrest And Cell Death - A Genetic System For Identifying Apoptosis Inhibiting Genes Biochemical Society Transactions. 24. DOI: 10.1042/Bst024599Sb  0.389
1994 Evan G, Harrington E, Fanidi A, Land H, Amati B, Bennett M. Integrated control of cell proliferation and cell death by the c-myc oncogene. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 345: 269-75. PMID 7846125 DOI: 10.1098/Rstb.1994.0105  0.468
1994 Fanidi A, Evan G. Applications of apoptosis: Making death pay Trends in Biotechnology. 12: 219-221. PMID 7765068 DOI: 10.1016/0167-7799(94)90119-8  0.312
1992 Lee SW, Purushotham KR, Littlewood T, Evan G, Zelles T, Blazsek J, Nakagawa Y, Humphreys-Beher MG. Down-regulation of cellular proto-oncogenes during inhibition of rat parotid acinar cell proliferation. Biochimica Et Biophysica Acta. 1135: 115-122. PMID 1616931 DOI: 10.1016/0167-4889(92)90126-V  0.34
1987 Sikora K, Chan S, Evan G, Gabra H, Markham N, Stewart J, Watson J. c-myc oncogene expression in colorectal cancer. Cancer. 59: 1289-1295. PMID 3545431 DOI: 10.1002/1097-0142(19870401)59:7<1289::Aid-Cncr2820590710>3.0.Co;2-O  0.342
1987 Chan S, Gabra H, Hill F, Evan G, Sikora K. A novel tumour marker related to the c-myc oncogene product. Molecular and Cellular Probes. 1: 73-82. PMID 3331171 DOI: 10.1016/0890-8508(87)90008-9  0.308
1987 Hunt SP, Pini A, Evan G. Induction of c-fos-like protein in spinal cord neurons following sensory stimulation. Nature. 328: 632-4. PMID 3112583 DOI: 10.1038/328632A0  0.328
1987 Sikora K, Evan G, Watson J. Oncogenes and germ cell tumours International Journal of Andrology. 10: 57-67. PMID 2438233 DOI: 10.1111/J.1365-2605.1987.Tb00166.X  0.334
1986 Evan G. Growth factors, receptors and oncogenes Trends in Genetics. 2: 2-3. DOI: 10.1016/0168-9525(86)90151-4  0.34
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