Year |
Citation |
Score |
2002 |
Cha S, Nagashima H, Peck AB, Humphreys-Beher MG. IDD3 and IDD5 alleles from nod mice mediate Sjögren's syndrome-like autoimmunity. Advances in Experimental Medicine and Biology. 506: 1035-9. PMID 12614028 DOI: 10.1007/978-1-4615-0717-8_146 |
0.63 |
|
2002 |
Humphreys-Beher MG, Brayer J, Cha S, Nagashima H, Diggs S, Peck AB. Immunogenetics of autoimmune exocrinopathy in the nod mouse: more than meets the eye. Advances in Experimental Medicine and Biology. 506: 999-1007. PMID 12614023 DOI: 10.1007/978-1-4615-0717-8_141 |
0.618 |
|
2002 |
Cha S, Nagashima H, Brown VB, Peck AB, Humphreys-Beher MG. Two NOD Idd-associated intervals contribute synergistically to the development of autoimmune exocrinopathy (Sjögren's syndrome) on a healthy murine background. Arthritis and Rheumatism. 46: 1390-8. PMID 12115247 DOI: 10.1002/Art.10258 |
0.658 |
|
2002 |
Cha S, Peck AB, Humphreys-Beher MG. Progress in understanding autoimmune exocrinopathy using the non-obese diabetic mouse: an update. Critical Reviews in Oral Biology and Medicine : An Official Publication of the American Association of Oral Biologists. 13: 5-16. PMID 12097234 DOI: 10.1177/154411130201300103 |
0.675 |
|
2002 |
Johansson AC, Nakken B, Sundler M, Lindqvist AK, Johannesson M, Alarcón-Riquelme M, Bolstad AI, Humphreys-Beher MG, Jonsson R, Skarstein K, Holmdahl R. The genetic control of sialadenitis versus arthritis in a NOD.QxB10.Q F2 cross. European Journal of Immunology. 32: 243-50. PMID 11782015 DOI: 10.1002/1521-4141(200201)32:1<243::Aid-Immu243>3.0.Co;2-X |
0.367 |
|
2001 |
Cha S, van Blockland SC, Versnel MA, Homo-Delarche F, Nagashima H, Brayer J, Peck AB, Humphreys-Beher MG. Abnormal organogenesis in salivary gland development may initiate adult onset of autoimmune exocrinopathy. Experimental and Clinical Immunogenetics. 18: 143-60. PMID 11549844 DOI: 10.1159/000049194 |
0.647 |
|
2001 |
Nagy A, Nagashima H, Cha S, Oxford GE, Zelles T, Peck AB, Humphreys-Beher MG. Reduced oral wound healing in the NOD mouse model for type 1 autoimmune diabetes and its reversal by epidermal growth factor supplementation. Diabetes. 50: 2100-4. PMID 11522677 DOI: 10.2337/Diabetes.50.9.2100 |
0.651 |
|
2001 |
Brayer JB, Cha S, Nagashima H, Yasunari U, Lindberg A, Diggs S, Martinez J, Goa J, Humphreys-Beher MG, Peck AB. IL-4-dependent effector phase in autoimmune exocrinopathy as defined by the NOD.IL-4-gene knockout mouse model of Sjögren's syndrome. Scandinavian Journal of Immunology. 54: 133-40. PMID 11439159 DOI: 10.1046/J.1365-3083.2001.00958.X |
0.62 |
|
2001 |
Clarke MY, Brayer J, Heintz K, Nagashima H, Cha S, Oxford GE, Nanni JM, Peck AB, Zelles T, Humphreys-Beher MG. Differential absorption and distribution of epidermal growth factor and insulin-like growth factor in diabetic NOD mice. Journal of Diabetes and Its Complications. 15: 103-11. PMID 11274907 DOI: 10.1016/S1056-8727(00)00136-7 |
0.656 |
|
2001 |
Masago R, Aiba-Masago S, Talal N, Zuluaga FJ, Al-Hashimi I, Moody M, Lau CA, Peck AB, Brayer J, Humphreys-Beher MG, Dang H. Elevated proapoptotic Bax and caspase 3 activation in the NOD.scid model of Sjögren's syndrome. Arthritis and Rheumatism. 44: 693-702. PMID 11263785 DOI: 10.1002/1529-0131(200103)44:3<693::Aid-Anr119>3.0.Co;2-7 |
0.348 |
|
2001 |
Nakagawa Y, Ishii H, Saito T, Wakui T, Sato T, Ishibashii K, Humphreys-Beher MG. Effects of chronic administration of pilocarpine on saliva secretion in streptozotocin-induced diabetic mice Oral Therapeutics and Pharmacology. 20: 96-103. DOI: 10.11263/Jsotp1982.20.96 |
0.411 |
|
2000 |
Koller MM, Maeda N, Scarpace PJ, Humphreys-Beher MG. Desipramine changes salivary gland function, oral microbiota, and oral health in rats European Journal of Pharmacology. 408: 91-98. PMID 11070187 DOI: 10.1016/S0014-2999(00)00770-6 |
0.31 |
|
2000 |
Nguyen KH, Brayer J, Cha S, Diggs S, Yasunari U, Hilal G, Peck AB, Humphreys-Beher MG. Evidence for antimuscarinic acetylcholine receptor antibody-mediated secretory dysfunction in nod mice. Arthritis and Rheumatism. 43: 2297-306. PMID 11037890 DOI: 10.1002/1529-0131(200010)43:10<2297::Aid-Anr18>3.0.Co;2-X |
0.644 |
|
2000 |
Oxford GE, Tayari L, Barfoot MD, Peck AB, Tanaka Y, Humphreys-Beher MG. Salivary EGF levels reduced in diabetic patients. Journal of Diabetes and Its Complications. 14: 140-5. PMID 10989322 DOI: 10.1016/S1056-8727(00)00073-8 |
0.36 |
|
2000 |
Brayer J, Lowry J, Cha S, Robinson CP, Yamachika S, Peck AB, Humphreys-Beher MG. Alleles from chromosomes 1 and 3 of NOD mice combine to influence Sjögren's syndrome-like autoimmune exocrinopathy. The Journal of Rheumatology. 27: 1896-904. PMID 10955330 |
0.641 |
|
1999 |
Humphreys-Beher MG, Peck AB, Dang H, Talal N. The role of apoptosis in the initiation of the autoimmune response in Sjögren's syndrome. Clinical and Experimental Immunology. 116: 383-387. PMID 10361223 DOI: 10.1046/J.1365-2249.1999.00888.X |
0.305 |
|
1999 |
Humphreys-Beher MG, Brayer J, Yamachika S, Peck AB, Jonsson R. An alternative perspective to the immune response in autoimmune exocrinopathy: induction of functional quiescence rather than destructive autoaggression. Scandinavian Journal of Immunology. 49: 7-10. PMID 10023850 DOI: 10.1046/J.1365-3083.1999.00490.X |
0.354 |
|
1999 |
Humphreys-Beher MG, Peck AB. New concepts for the development of autoimmune exocrinopathy derived from studies with the NOD mouse model Archives of Oral Biology. 44: S21-S25. DOI: 10.1016/S0003-9969(99)90008-0 |
0.49 |
|
1998 |
Robinson CP, Brayer J, Yamachika S, Esch TR, Peck AB, Stewart CA, Peen E, Jonsson R, Humphreys-Beher MG. Transfer of human serum IgG to nonobese diabetic Igmu null mice reveals a role for autoantibodies in the loss of secretory function of exocrine tissues in Sjögren's syndrome. Proceedings of the National Academy of Sciences of the United States of America. 95: 7538-43. PMID 9636185 DOI: 10.1073/Pnas.95.13.7538 |
0.485 |
|
1998 |
Robinson CP, Cornelius J, Bounous DI, Yamamoto H, Humphreys-Beher MG, Peck AB. Infiltrating lymphocyte populations and cytokine production in the salivary and lacrimal glands of autoimmune NOD mice. Advances in Experimental Medicine and Biology. 438: 493-7. PMID 9634926 DOI: 10.1007/978-1-4615-5359-5_68 |
0.416 |
|
1998 |
Robinson CP, Cornelius J, Bounous DE, Yamamoto H, Humphreys-Beher MG, Peck AB. Characterization of the changing lymphocyte populations and cytokine expression in the exocrine tissues of autoimmune NOD mice. Autoimmunity. 27: 29-44. PMID 9482205 DOI: 10.3109/08916939809008035 |
0.33 |
|
1998 |
Robinson CP, Yamachika S, Bounous DI, Brayer J, Jonsson R, Holmdahl R, Peck AB, Humphreys-Beher MG. A novel NOD-derived murine model of primary Sjögren's syndrome. Arthritis and Rheumatism. 41: 150-6. PMID 9433880 DOI: 10.1002/1529-0131(199801)41:1<150::Aid-Art18>3.0.Co;2-T |
0.436 |
|
1998 |
Zeng T, Yamamoto H, Bowen E, Broverman RL, Nguyen KH, Humphreys-Beher MG. Cell cycle control in isoproterenol-induced murine salivary acinar cell proliferation. Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology. 115: 271-9. PMID 9375366 DOI: 10.1016/S0742-8413(96)00140-5 |
0.301 |
|
1997 |
Maeda N, Okamoto M, Nakagawa Y, Fujita H, Humphreys-Beher MG. Effects of chronic isoproterenol treatment or submandibular and sublingual ablation on microflora of mouse tooth surfaces. Microbiology and Immunology. 41: 513-7. PMID 9272696 DOI: 10.1111/J.1348-0421.1997.Tb01886.X |
0.348 |
|
1997 |
Robinson CP, Yamachika S, Alford CE, Cooper C, Pichardo EL, Shah N, Peck AB, Humphreys-Beher MG. Elevated levels of cysteine protease activity in saliva and salivary glands of the nonobese diabetic (NOD) mouse model for Sjögren syndrome. Proceedings of the National Academy of Sciences of the United States of America. 94: 5767-71. PMID 9159148 DOI: 10.1073/Pnas.94.11.5767 |
0.451 |
|
1997 |
Robinson CP, Bounous DI, Alford CE, Nguyen KH, Nanni JM, Peck AB, Humphreys-Beher MG. PSP expression in murine lacrimal glands and function as a bacteria binding protein in exocrine secretions. The American Journal of Physiology. 272: G863-71. PMID 9142919 DOI: 10.1152/Ajpgi.1997.272.4.G863 |
0.433 |
|
1997 |
Nakagawa Y, Oxford GE, Ishibashi K, Yamamoto H, Maeda N, Bowen E, Brayer J, Humphreys-Beher MG. Gastrointestinal absorption of insulin-like growth factor in the mouse in the absence of salivary insulin-like growth factor binding protein. Biochemical Pharmacology. 53: 233-40. PMID 9037256 DOI: 10.1016/S0006-2952(96)00733-2 |
0.415 |
|
1997 |
Yamamoto H, Ishibashi K, Nakagawa Y, Maeda N, Zeng T, Robinson CP, Oxford GE, Chegini N, Humphreys-Beher MG. Detection of alterations in the levels of neuropeptides and salivary gland responses in the non-obese diabetic mouse model for autoimmune sialoadenitis. Scandinavian Journal of Immunology. 45: 55-61. PMID 9010501 DOI: 10.1046/j.1365-3083.1997.d01-375.x |
0.329 |
|
1996 |
Humphreys-Beher MG. Animal models for autoimmune disease-associated xerostomia and xerophthalmia. Advances in Dental Research. 10: 73-5. PMID 8934930 DOI: 10.1177/08959374960100011501 |
0.417 |
|
1996 |
Bu R, Purushotham KR, Kerr M, Tao Z, Jonsson R, Olofsson J, Humphreys-Beher MG. Alterations in the level of phosphotyrosine signal transduction constituents in human parotid tumors. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 211: 257-64. PMID 8633106 DOI: 10.3181/00379727-211-43969 |
0.304 |
|
1996 |
Robinson CP, Yamamoto H, Peck AB, Humphreys-Beher MG. Genetically programmed development of salivary gland abnormalities in the NOD (nonobese diabetic)-scid mouse in the absence of detectable lymphocytic infiltration: a potential trigger for sialoadenitis of NOD mice. Clinical Immunology and Immunopathology. 79: 50-9. PMID 8612351 DOI: 10.1006/Clin.1996.0050 |
0.457 |
|
1996 |
Purushotham KR, Wang P, Humphreys-Beher MG. Effect of vanadate on amylase secretion and protein tyrosine phosphatase activity in the rat parotid gland. Molecular and Cellular Biochemistry. 152: 87-94. PMID 8609916 DOI: 10.1007/Bf01076467 |
0.33 |
|
1996 |
Yamamoto H, Sims NE, Macauley SP, Nguyen KH, Nakagawa Y, Humphreys-Beher MG. Alterations in the secretory response of non-obese diabetic (NOD) mice to muscarinic receptor stimulation. Clinical Immunology and Immunopathology. 78: 245-55. PMID 8605700 DOI: 10.1006/Clin.1996.0036 |
0.438 |
|
1996 |
Purushotham KR, Offenmüller K, Bui AT, Zelles T, Blazsek J, Schultz GS, Humphreys-Beher MG. Absorption of epidermal growth factor occurs through the gastrointestinal tract and oral cavity in adult rats. The American Journal of Physiology. 269: G867-73. PMID 8572218 DOI: 10.1152/Ajpgi.1995.269.6.G867 |
0.313 |
|
1995 |
Hu Y, Humphreys-Beher MG. Decreased levels of adenylate cyclase contribute to the down-regulation of beta-adrenergic signal transduction in the salivary glands of the non-obese diabetic (NOD) mouse. Autoimmunity. 21: 137-142. PMID 8679903 DOI: 10.3109/08916939508993362 |
0.397 |
|
1995 |
Wang PL, Purushotham KR, Humphreys-Beher MG. Activation of SH2-containing proteins by insulin in proliferating mouse parotid gland acinar cells. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 207: 317-23. PMID 7800688 DOI: 10.3181/00379727-207-43822 |
0.339 |
|
1995 |
Kerr M, Lee A, Wang PL, Purushotham KR, Chegini N, Yamamoto H, Humphreys-Beher MG. Detection of insulin and insulin-like growth factors I and II in saliva and potential synthesis in the salivary glands of mice. Effects of type 1 diabetes mellitus. Biochemical Pharmacology. 49: 1521-31. PMID 7763295 DOI: 10.1016/0006-2952(95)00017-T |
0.372 |
|
1995 |
Purushotham KR, Zelles T, Blazsek J, Wang P, Paul GA, Kerr M, Humphreys-Beher MG. Effect of EGF on rat parotid gland secretory function. Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology. 110: 7-14. PMID 7538411 DOI: 10.1016/0742-8413(94)00083-M |
0.319 |
|
1994 |
Humphreys-Beher MG, Macauley SP, Chegini N, Setten Gv, Purushotham K, Stewart C, Wheeler TT, Schultz GS. Characterization of the synthesis and secretion of transforming growth factor-alpha from salivary glands and saliva. Endocrinology. 134: 963-970. PMID 8299590 DOI: 10.1210/Endo.134.2.8299590 |
0.316 |
|
1994 |
Wang PL, Purushotham KR, Humphreys-Beher MG. Effect of chronic insulin administration on mouse parotid and submandibular gland function. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 205: 353-61. PMID 8171060 DOI: 10.3181/00379727-205-43718 |
0.362 |
|
1994 |
Hu Y, Purushotham KR, Wang P, Dawson R, Humphreys-Beher MG. Downregulation of beta-adrenergic receptors and signal transduction response in salivary glands of NOD mice. The American Journal of Physiology. 266: G433-43. PMID 8166282 DOI: 10.1152/Ajpgi.1994.266.3.G433 |
0.367 |
|
1994 |
Kerr M, Fischer JE, Purushotham KR, Gao D, Nakagawa Y, Maeda N, Ghanta V, Hiramato R, Chegini N, Humphreys-Beher MG. Characterization of the synthesis and expression of the GTA-kinase from transformed and normal rodent cells Biochimica Et Biophysica Acta. 1218: 375-387. PMID 8049264 DOI: 10.1016/0167-4781(94)90191-0 |
0.318 |
|
1994 |
Purushotham KR, Paul GA, Wang P, Humphreys-Beher MG. Characterization of an SH2 containing protein tyrosine phosphatase in rat parotid gland acinar cells. Life Sciences. 54: 1185-94. PMID 7512184 DOI: 10.1016/0024-3205(94)00840-X |
0.322 |
|
1993 |
Purushotham KR, Nakagawa Y, Kurian P, Patel R, Crews FT, Humphreys-Beher MG. Activation of phosphatidylinositol 3-kinase and phosphatidylinositol 4-kinase during rat parotid acinar cell proliferation. Biochimica Et Biophysica Acta. 1178: 40-8. PMID 8392376 DOI: 10.1016/0167-4889(93)90107-Z |
0.316 |
|
1993 |
Humphreys-Beher MG, Brinkley L, Purushotham KR, Wang P, Nakagawa Y, Dusek D, Kerr M, Chegini N, Chan EKL. Characterization of Antinuclear Autoantibodies Present in the Serum from Nonobese Diabetic (NOD) Mice Clinical Immunology and Immunopathology. 68: 350-356. PMID 8370186 DOI: 10.1006/Clin.1993.1137 |
0.446 |
|
1993 |
Purushotham KR, Wang PL, Dolce C, Zelles T, Blazsek J, Humphreys-Beher MG. Effects of surgical ovariectomy on rat salivary gland function. Archives of Oral Biology. 38: 779-84. PMID 7694568 DOI: 10.1016/0003-9969(93)90074-V |
0.322 |
|
1992 |
Maeda N, Purushotham KR, Koller MM, Humphreys-Beher MG. Regulation of cell-surface galactosyltransferase in isoproterenol-treated mouse parotid glands. Archives of Oral Biology. 36: 491-5. PMID 1776922 DOI: 10.1016/0003-9969(91)90141-G |
0.349 |
|
1992 |
Nakagawa Y, Gammichia J, Purushotham KR, Schneyer CA, Humphreys-Beher MG. Epidermal growth factor activation of rat parotid gland adenylate cyclase and mediation by a GTP-binding regulatory protein. Biochemical Pharmacology. 42: 2333-40. PMID 1662511 DOI: 10.1016/0006-2952(91)90238-Z |
0.33 |
|
1992 |
Purushotham KR, Dunn WA, Schneyer CA, Humphreys-Beher MG. A novel mechanism for isoprenaline-stimulated proliferation of rat parotid acinar cells involving the epidermal growth factor receptor and cell surface galactosyltransferase. The Biochemical Journal. 767-76. PMID 1622394 DOI: 10.1042/Bj2840767 |
0.341 |
|
1992 |
Lee SW, Purushotham KR, Littlewood T, Evan G, Zelles T, Blazsek J, Nakagawa Y, Humphreys-Beher MG. Down-regulation of cellular proto-oncogenes during inhibition of rat parotid acinar cell proliferation. Biochimica Et Biophysica Acta. 1135: 115-122. PMID 1616931 DOI: 10.1016/0167-4889(92)90126-V |
0.331 |
|
1992 |
Schneyer CA, Humphreys-Beher M, Hall HD. Nerve growth factor effects on inhibition by submandibular gland ablation or autonomic denervation of activity-induced parotid growth. Journal of the Autonomic Nervous System. 37: 137-44. PMID 1607599 DOI: 10.1016/0165-1838(92)90242-9 |
0.309 |
|
1992 |
Hu Y, Nakagawa Y, Purushotham KR, Humphreys-Beher MG. Functional changes in salivary glands of autoimmune disease-prone NOD mice. The American Journal of Physiology. 263: E607-14. PMID 1415679 DOI: 10.1152/ajpendo.1992.263.4.E607 |
0.348 |
|
1992 |
Nakagawa Y, Purushotham KR, Wang P, Fischer JE, Dunn WA, Schneyer CA, Humphreys-Beher MG. Alterations in the subcellular distribution of p21ras-GTPase activating protein in proliferating rat acinar cells. Biochemical and Biophysical Research Communications. 187: 1172-1179. PMID 1382416 DOI: 10.1016/0006-291X(92)91320-P |
0.306 |
|
1992 |
Schneyer CA, Hall HD, Humphreys-Beher MG. Effects of nerve growth factor on cyclocytidine-induced growth responses of sympathectomized parotid or parotid of partially desalivated rat. Journal of the Autonomic Nervous System. 38: 29-35. PMID 1375237 DOI: 10.1016/0165-1838(92)90213-Z |
0.312 |
|
1991 |
Purushotham KR, Zelles T, Humphreys-Beher MG. Role of protein phosphorylation and inositol phospholipid turnover in rat parotid gland proliferation. Molecular and Cellular Biochemistry. 102: 19-33. PMID 1904983 DOI: 10.1007/Bf00232155 |
0.333 |
|
1990 |
Schneyer CA, Humphreys-Beher MG. Nerve growth factor-induced increase in [3H]thymidine incorporation into pancreas of young rats and its partial blockade by propranolol or partial sialoadenectomy. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 194: 204-8. PMID 2162538 DOI: 10.3181/00379727-194-43079 |
0.308 |
|
1990 |
Humphreys-Beher MG, Maeda N, Purushotham KR, Morgan A, Cassisi N. Increased expression of the enzyme β1-4-galactosyltransferase is associated with human parotid neoplasms Experimental Biology and Medicine. 193: 293-300. PMID 2157218 DOI: 10.3181/00379727-193-43038 |
0.304 |
|
1990 |
Humphreys-Beher MG, Zelles T, Maeda N, Purushotham KR, Cassisi N, Schneyer CA. Cell-surface galactosyltransferase acts as a modulator of rat and human acinar cell proliferation. Advances in Dental Research. 4: 45-60. PMID 2119592 DOI: 10.1177/08959374900040010801 |
0.361 |
|
1990 |
Humphreys-Beher MG, Zelles T, Maeda N, Purushotham KR, Schneyer CA. Cell surface galactosyltransferase acts as a general modulator of rat acinar cell proliferation. Molecular and Cellular Biochemistry. 95: 1-11. PMID 2114524 DOI: 10.1007/Bf00219524 |
0.371 |
|
1990 |
Schneyer CA, Humphreys-Beher MG. Nerve growth factor-induced increase in [3H]thymidine incorporation into parotid and submandibular glands of young rats and its partial blockade by propranolol or partial sialoadenectomy. Biochemical Pharmacology. 39: 1679-86. PMID 2111703 DOI: 10.1016/0006-2952(90)90111-W |
0.347 |
|
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