| Year |
Citation |
Score |
| 2020 |
Kessel D, Reiners JJ. Photodynamic therapy: autophagy and mitophagy, apoptosis and paraptosis. Autophagy. 16: 2098-2101. PMID 32584644 DOI: 10.1080/15548627.2020.1783823 |
0.344 |
|
| 2017 |
Kessel D, Reiners JJ. Effects of Combined Lysosomal and Mitochondrial Photodamage in a Non-small-Cell Lung Cancer Cell Line: The Role of Paraptosis. Photochemistry and Photobiology. 93: 1502-1508. PMID 28696570 DOI: 10.1111/Php.12805 |
0.419 |
|
| 2016 |
Wang J, Zhou JY, Kho D, Reiners JJ, Wu GS. Role for DUSP1 (dual specificity phosphatase 1) in the regulation of autophagy. Autophagy. 0. PMID 27459239 DOI: 10.1080/15548627.2016.1203483 |
0.402 |
|
| 2016 |
Joiakim A, Mathieu PA, Shelp C, Boerner J, Reiners JJ. Epidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A Cells. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 44: 665-71. PMID 26953171 DOI: 10.1124/Dmd.115.066274 |
0.366 |
|
| 2015 |
Kessel D, Reiners JJ. Promotion of Proapoptotic Signals by Lysosomal Photodamage. Photochemistry and Photobiology. 91: 931-6. PMID 25873082 DOI: 10.1111/Php.12456 |
0.389 |
|
| 2014 |
Kessel D, Reiners JJ. Enhanced efficacy of photodynamic therapy via a sequential targeting protocol. Photochemistry and Photobiology. 90: 889-95. PMID 24617972 DOI: 10.1111/Php.12270 |
0.32 |
|
| 2012 |
Kessel D, Reiners J. Light-Activated Pharmaceuticals: Mechanisms and Detection. Israel Journal of Chemistry. 52: 674-680. PMID 23990688 DOI: 10.1002/Ijch.201100059 |
0.302 |
|
| 2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Reiners JJ, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.304 |
|
| 2012 |
Kessel DH, Price M, Reiners JJ. ATG7 deficiency suppresses apoptosis and cell death induced by lysosomal photodamage. Autophagy. 8: 1333-41. PMID 22889762 DOI: 10.4161/Auto.20792 |
0.436 |
|
| 2012 |
Elliott A, Joiakim A, Mathieu PA, Duniec-Dmuchowski Z, Kocarek TA, Reiners JJ. p-Anilinoaniline enhancement of dioxin-induced CYP1A1 transcription and aryl hydrocarbon receptor occupancy of CYP1A1 promoter: role of the cell cycle. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 1032-40. PMID 22344700 DOI: 10.1124/Dmd.111.042549 |
0.409 |
|
| 2011 |
Wojtkowiak JW, Sane KM, Kleinman M, Sloane BF, Reiners JJ, Mattingly RR. Aborted autophagy and nonapoptotic death induced by farnesyl transferase inhibitor and lovastatin. The Journal of Pharmacology and Experimental Therapeutics. 337: 65-74. PMID 21228063 DOI: 10.1124/Jpet.110.174573 |
0.417 |
|
| 2011 |
Kessel D, Price M, Caruso J, Reiners J. Effects of photodynamic therapy on the endocytic pathway. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 10: 491-8. PMID 21125114 DOI: 10.1039/C0Pp00276C |
0.362 |
|
| 2011 |
Reiners JJ, Kleinman M, Kessel D, Mathieu PA, Caruso JA. Nonesterified cholesterol content of lysosomes modulates susceptibility to oxidant-induced permeabilization. Free Radical Biology & Medicine. 50: 281-94. PMID 21074609 DOI: 10.1016/J.Freeradbiomed.2010.11.006 |
0.345 |
|
| 2010 |
Kraniak JM, Sun D, Mattingly RR, Reiners JJ, Tainsky MA. The role of neurofibromin in N-Ras mediated AP-1 regulation in malignant peripheral nerve sheath tumors. Molecular and Cellular Biochemistry. 344: 267-76. PMID 20680410 DOI: 10.1007/S11010-010-0551-1 |
0.322 |
|
| 2010 |
Sane KM, Mynderse M, Lalonde DT, Dean IS, Wojtkowiak JW, Fouad F, Borch RF, Reiners JJ, Gibbs RA, Mattingly RR. A novel geranylgeranyl transferase inhibitor in combination with lovastatin inhibits proliferation and induces autophagy in STS-26T MPNST cells. The Journal of Pharmacology and Experimental Therapeutics. 333: 23-33. PMID 20086055 DOI: 10.1124/Jpet.109.160192 |
0.41 |
|
| 2010 |
Reiners JJ, Agostinis P, Berg K, Oleinick NL, Kessel D. Assessing autophagy in the context of photodynamic therapy. Autophagy. 6: 7-18. PMID 19855190 DOI: 10.4161/Auto.6.1.10220 |
0.422 |
|
| 2009 |
Reiners JJ, Kleinman M, Joiakim A, Mathieu PA. The chemotherapeutic agents XK469 (2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid) and SH80 (2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy}propionic acid) inhibit cytokinesis and promote polyploidy and induce senescence. The Journal of Pharmacology and Experimental Therapeutics. 328: 796-806. PMID 19066341 DOI: 10.1124/Jpet.108.144808 |
0.434 |
|
| 2008 |
Dilworth JT, Wojtkowiak JW, Mathieu P, Tainsky MA, Reiners JJ, Mattingly RR, Hancock CN. Suppression of proliferation of two independent NF1 malignant peripheral nerve sheath tumor cell lines by the pan-ErbB inhibitor CI-1033. Cancer Biology & Therapy. 7: 1938-46. PMID 18927496 DOI: 10.4161/Cbt.7.12.6942 |
0.323 |
|
| 2008 |
Elliott A, Reiners JJ. Suppression of autophagy enhances the cytotoxicity of the DNA-damaging aromatic amine p-anilinoaniline. Toxicology and Applied Pharmacology. 232: 169-79. PMID 18655802 DOI: 10.1016/J.Taap.2008.06.017 |
0.436 |
|
| 2008 |
Kessel D, Price M, Reiners JJ. The Bcl-2 antagonist HA14-1 forms a fluorescent albumin complex that can be mistaken for several oxidized ROS probes. Photochemistry and Photobiology. 84: 1272-6. PMID 18513234 DOI: 10.1111/J.1751-1097.2008.00371.X |
0.308 |
|
| 2008 |
Wojtkowiak JW, Fouad F, LaLonde DT, Kleinman MD, Gibbs RA, Reiners JJ, Borch RF, Mattingly RR. Induction of apoptosis in neurofibromatosis type 1 malignant peripheral nerve sheath tumor cell lines by a combination of novel farnesyl transferase inhibitors and lovastatin. The Journal of Pharmacology and Experimental Therapeutics. 326: 1-11. PMID 18367665 DOI: 10.1124/Jpet.107.135830 |
0.37 |
|
| 2007 |
Kessel D, Reiners JJ. Apoptosis and autophagy after mitochondrial or endoplasmic reticulum photodamage. Photochemistry and Photobiology. 83: 1024-8. PMID 17880495 DOI: 10.1111/J.1751-1097.2007.00088.X |
0.385 |
|
| 2007 |
Clark MK, Scott SA, Wojtkowiak J, Chirco R, Mathieu P, Reiners JJ, Mattingly RR, Borch RF, Gibbs RA. Synthesis, biochemical, and cellular evaluation of farnesyl monophosphate prodrugs as farnesyltransferase inhibitors. Journal of Medicinal Chemistry. 50: 3274-82. PMID 17555307 DOI: 10.1021/Jm0701829 |
0.357 |
|
| 2007 |
Kessel D, Reiners JJ, Hazeldine ST, Polin L, Horwitz JP. The role of autophagy in the death of L1210 leukemia cells initiated by the new antitumor agents, XK469 and SH80. Molecular Cancer Therapeutics. 6: 370-9. PMID 17237296 DOI: 10.1158/1535-7163.Mct-05-0386 |
0.429 |
|
| 2007 |
Kessel D, Reiners JJ. Initiation of apoptosis and autophagy by the Bcl-2 antagonist HA14-1 Cancer Letters. 249: 294-299. PMID 17055152 DOI: 10.1016/J.Canlet.2006.09.009 |
0.421 |
|
| 2006 |
Caruso JA, Reiners JJ. Proteolysis of HIP during apoptosis occurs within a region similar to the BID loop. Apoptosis : An International Journal On Programmed Cell Death. 11: 1877-85. PMID 17013759 DOI: 10.1007/S10495-006-0083-Z |
0.345 |
|
| 2006 |
Kessel D, Vicente MGH, Reiners JJ. Initiation of apoptosis and autophagy by photodynamic therapy Autophagy. 2: 289-290. PMID 16921269 DOI: 10.4161/Auto.2792 |
0.43 |
|
| 2006 |
Dilworth JT, Kraniak JM, Wojtkowiak JW, Gibbs RA, Borch RF, Tainsky MA, Reiners JJ, Mattingly RR. Molecular targets for emerging anti-tumor therapies for neurofibromatosis type 1. Biochemical Pharmacology. 72: 1485-92. PMID 16797490 DOI: 10.1016/J.Bcp.2006.04.010 |
0.304 |
|
| 2006 |
Kessel D, Vicente MG, Reiners JJ. Initiation of apoptosis and autophagy by photodynamic therapy. Lasers in Surgery and Medicine. 38: 482-8. PMID 16615135 DOI: 10.1002/Lsm.20334 |
0.322 |
|
| 2006 |
Caruso JA, Mathieu PA, Joiakim A, Zhang H, Reiners JJ. Aryl hydrocarbon receptor modulation of tumor necrosis factor-alpha-induced apoptosis and lysosomal disruption in a hepatoma model that is caspase-8-independent. The Journal of Biological Chemistry. 281: 10954-67. PMID 16446372 DOI: 10.1074/Jbc.M508383200 |
0.451 |
|
| 2006 |
Mattingly RR, Kraniak JM, Dilworth JT, Mathieu P, Bealmear B, Nowak JE, Benjamins JA, Tainsky MA, Reiners JJ. The mitogen-activated protein kinase/extracellular signal-regulated kinase kinase inhibitor PD184352 (CI-1040) selectively induces apoptosis in malignant schwannoma cell lines. The Journal of Pharmacology and Experimental Therapeutics. 316: 456-65. PMID 16239399 DOI: 10.1124/Jpet.105.091454 |
0.361 |
|
| 2006 |
Kessel D, Reiners JJ. Cell death pathways associated with PDT Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6139. DOI: 10.1117/12.639925 |
0.41 |
|
| 2005 |
Caruso JA, Mathieu PA, Reiners JJ. Sphingomyelins suppress the targeted disruption of lysosomes/endosomes by the photosensitizer NPe6 during photodynamic therapy. The Biochemical Journal. 392: 325-34. PMID 15943580 DOI: 10.1042/Bj20050313 |
0.364 |
|
| 2005 |
Reiners JJ, Kessel D. Susceptibility of myelomonocytic leukemia U937 cells to the induction of apoptosis by the non-peptidic Bcl-2 ligand HA14-1 is cell cycle phase-dependent Cancer Letters. 221: 153-163. PMID 15808401 DOI: 10.1016/J.Canlet.2004.09.012 |
0.388 |
|
| 2004 |
Joiakim A, Mathieu PA, Elliott AA, Reiners JJ. Superinduction of CYP1A1 in MCF10A cultures by cycloheximide, anisomycin, and puromycin: a process independent of effects on protein translation and unrelated to suppression of aryl hydrocarbon receptor proteolysis by the proteasome. Molecular Pharmacology. 66: 936-47. PMID 15385644 DOI: 10.1124/Mol.66.4 |
0.398 |
|
| 2004 |
Wang G, Chuang L, Zhang X, Colton S, Dombkowski A, Reiners J, Diakiw A, Xu XS. The initiative role of XPC protein in cisplatin DNA damaging treatment‐mediated cell cycle regulation Nucleic Acids Research. 32: 2231-2240. PMID 15107491 DOI: 10.1093/Nar/Gkh541 |
0.342 |
|
| 2004 |
Caruso JA, Mathieu PA, Joiakim A, Leeson B, Kessel D, Sloane BF, Reiners JJ. Differential susceptibilities of murine hepatoma 1c1c7 and Tao cells to the lysosomal photosensitizer NPe6: influence of aryl hydrocarbon receptor on lysosomal fragility and protease contents. Molecular Pharmacology. 65: 1016-28. PMID 15044632 DOI: 10.1124/Mol.65.4.1016 |
0.451 |
|
| 2003 |
Joiakim A, Mathieu PA, Palermo C, Gasiewicz TA, Reiners JJ. The Jun N-terminal kinase inhibitor SP600125 is a ligand and antagonist of the aryl hydrocarbon receptor. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 1279-82. PMID 14570754 DOI: 10.1124/Dmd.31.11.1279 |
0.314 |
|
| 2003 |
Castelli M, Reiners J, Kessel D. Promotion of PDT Efficacy by Bile Acids Proceedings of Spie - the International Society For Optical Engineering. 4952: 10-16. DOI: 10.1117/12.473615 |
0.393 |
|
| 2002 |
Kessel D, Reiners JJ. Apoptotic response to photodynamic therapy versus the Bcl-2 antagonist HA14-1 Photochemistry and Photobiology. 76: 314-319. PMID 12403453 DOI: 10.1562/0031-8655(2002)076<0314:Artptv>2.0.Co;2 |
0.37 |
|
| 2002 |
Mattingly RR, Gibbs RA, Menard RE, Reiners JJ. Potent suppression of proliferation of a10 vascular smooth muscle cells by combined treatment with lovastatin and 3-allylfarnesol, an inhibitor of protein farnesyltransferase. The Journal of Pharmacology and Experimental Therapeutics. 303: 74-81. PMID 12235235 DOI: 10.1124/Jpet.102.036061 |
0.338 |
|
| 2002 |
States JC, Reiners JJ, Pounds JG, Kaplan DJ, Beauerle BD, McNeely SC, Mathieu P, McCabe MJ. Arsenite disrupts mitosis and induces apoptosis in SV40-transformed human skin fibroblasts. Toxicology and Applied Pharmacology. 180: 83-91. PMID 11969375 DOI: 10.1006/Taap.2002.9376 |
0.397 |
|
| 2002 |
Guo M, Mathieu PA, Linebaugh B, Sloane BF, Reiners JJ. Phorbol ester activation of a proteolytic cascade capable of activating latent transforming growth factor-betaL a process initiated by the exocytosis of cathepsin B. The Journal of Biological Chemistry. 277: 14829-37. PMID 11815600 DOI: 10.1074/Jbc.M108180200 |
0.336 |
|
| 2002 |
Guo M, Joiakim A, Dudley DT, Reiners JJ. Suppression of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated CYP1A1 and CYP1B1 induction by 12-O-tetradecanoylphorbol-13-acetate: role of transforming growth factor beta and mitogen-activated protein kinases. Biochemical Pharmacology. 62: 1449-57. PMID 11728381 DOI: 10.1016/S0006-2952(01)00801-2 |
0.395 |
|
| 2002 |
States JC, Reiners JJ, Pounds JG, Kaplan DJ, Beauerle BD, McNeely SC, Mathieu P, McCabe MJ. Erratum: Arsenite disrupts mitosis and induces apoptosis in SV40-transformed human skin fibroblasts (Toxicology and Applied Pharmacology (2002) 180; 2 (83-91)) Toxicology and Applied Pharmacology. 183. DOI: 10.1016/S0041-008X(02)99491-3 |
0.323 |
|
| 2001 |
McCabe MJ, Singh KP, Reiners JJ. Low Level Lead Exposure in Vitro Stimulates the Proliferation and Expansion of Alloantigen-Reactive CD4high T Cells Toxicology and Applied Pharmacology. 177: 219-231. PMID 11749121 DOI: 10.1006/Taap.2001.9307 |
0.339 |
|
| 2001 |
Caruso JA, Reiners JJ, Emond J, Shultz T, Tainsky MA, Alaoui-Jamali M, Batist G. Genetic alteration of chromosome 8 is a common feature of human mammary epithelial cell lines transformed in vitro with benzo[a]pyrene. Mutation Research. 473: 85-99. PMID 11166028 DOI: 10.1016/S0027-5107(00)00140-8 |
0.323 |
|
| 2000 |
Guo M, Joiakim A, Reiners JJ. Suppression of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated aryl hydrocarbon receptor transformation and CYP1A1 induction by the phosphatidylinositol 3-kinase inhibitor 2-(4-morpholinyl)-8-phenyl-4H-1- benzopyran-4-one (LY294002). Biochemical Pharmacology. 60: 635-42. PMID 10927021 DOI: 10.1016/S0006-2952(00)00379-8 |
0.366 |
|
| 2000 |
Reiners JJ, Mathieu P, Okafor C, Putt DA, Lash LH. Depletion of cellular glutathione by conditions used for the passaging of adherent cultured cells. Toxicology Letters. 115: 153-63. PMID 10802391 DOI: 10.1016/S0378-4274(00)00189-2 |
0.354 |
|
| 2000 |
Kessel D, Luo Y, Mathieu P, Reiners JJ. Determinants of the apoptotic response to lysosomal photodamage Photochemistry and Photobiology. 71: 196-200. PMID 10687394 DOI: 10.1562/0031-8655(2000)071<0196:Dotart>2.0.Co;2 |
0.39 |
|
| 2000 |
Guo M, Reiners JJ. Phorbol ester-induced production of cytostatic factors by normal and oncogenic Ha- ras -transformed human breast cell lines Carcinogenesis. 21: 1303-1312. DOI: 10.1093/Carcin/21.7.1303 |
0.367 |
|
| 1999 |
Reiners JJ, Clift R, Mathieu P. Suppression of cell cycle progression by flavonoids: dependence on the aryl hydrocarbon receptor. Carcinogenesis. 20: 1561-6. PMID 10426807 DOI: 10.1093/Carcin/20.8.1561 |
0.368 |
|
| 1999 |
Reiners JJ, Clift RE. Aryl hydrocarbon receptor regulation of ceramide-induced apoptosis in murine hepatoma 1c1c7 cells. A function independent of aryl hydrocarbon receptor nuclear translocator. The Journal of Biological Chemistry. 274: 2502-10. PMID 9891021 DOI: 10.1074/Jbc.274.4.2502 |
0.437 |
|
| 1998 |
Reiners JJ, Jones CL, Hong N, Myrand SP. Differential induction of Cyp1a1, Cyp1b1, Ahd4, and Nmo1 in murine skin tumors and adjacent normal epidermis by ligands of the aryl hydrocarbon receptor. Molecular Carcinogenesis. 21: 135-146. PMID 9496914 DOI: 10.1002/(Sici)1098-2744(199802)21:2<135::Aid-Mc8>3.0.Co;2-M |
0.318 |
|
| 1997 |
Jones CL, Reiners JJ. Differentiation status of cultured murine keratinocytes modulates induction of genes responsive to 2,3,7,8-tetrachlorodibenzo-p-dioxin Archives of Biochemistry and Biophysics. 347: 163-173. PMID 9367521 DOI: 10.1006/Abbi.1997.0350 |
0.351 |
|
| 1997 |
Reiners JJ, Jones CL, Hong N, Clift RE, Elferink C. Downregulation of aryl hydrocarbon receptor function and cytochrome p450 1A1 induction by expression of Ha-ras oncogenes Molecular Carcinogenesis. 19: 91-100. PMID 9210956 DOI: 10.1002/(Sici)1098-2744(199707)19:2<91::Aid-Mc4>3.0.Co;2-O |
0.364 |
|
| 1996 |
Singh KP, Yoon HL, Ratner S, Reiners JJ. Modulation of the development of humoral immunity by topically applied acetone, ethanol, and 12-O-tetradecanoylphorbol-13-acetate. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 33: 129-39. PMID 8812255 DOI: 10.1006/Faat.1996.0150 |
0.309 |
|
| 1994 |
Quan T, Reiners JJ, Bell AO, Hong N, States JC. Cytotoxicity and genotoxicity of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol in CYP1A1-expressing human fibroblasts quantitatively correlate with CYP1A1 expression level. Carcinogenesis. 15: 1827-1832. PMID 7923575 DOI: 10.1093/Carcin/15.9.1827 |
0.357 |
|
| 1993 |
Reiners JJ, Scholler A, Bischer P, Cantu AR, Pavone A. Suppression of Cytochrome P450 Cyp1A-1 Induction in Murine Hepatoma 1c1c7-Cells by 12-O-Tetradecanoylphorbol-13-Acetate and Inhibitors of Protein Kinase C Archives of Biochemistry and Biophysics. 301: 449-454. PMID 7681664 DOI: 10.1006/Abbi.1993.1170 |
0.367 |
|
| 1986 |
Fischer SM, Reiners JJ. 7,8-Benzoflavone: an inhibitor of prostaglandin synthesis and ornithine decarboxylase in murine epidermal cultures. Carcinogenesis. 7: 933-935. PMID 3458547 DOI: 10.1093/Carcin/7.6.933 |
0.347 |
|
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