David Langlais, Ph.D. - Publications

Affiliations: 
2011 Université de Montréal, Montréal, Canada 
Area:
Molecular Biology

34/63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Liang Y, Wang H, Seija N, Lin YH, Tung LT, Di Noia JM, Langlais D, Nijnik A. B-cell intrinsic regulation of antibody mediated immunity by histone H2A deubiquitinase BAP1. Frontiers in Immunology. 15: 1353138. PMID 38529289 DOI: 10.3389/fimmu.2024.1353138  0.307
2023 Wang H, Langlais D, Nijnik A. Histone H2A deubiquitinases in the transcriptional programs of development and hematopoiesis: a consolidated analysis. The International Journal of Biochemistry & Cell Biology. 157: 106384. PMID 36738766 DOI: 10.1016/j.biocel.2023.106384  0.359
2021 Mancini M, Charbonneau B, Langlais D, Vidal SM. The c-Rel transcription factor limits early interferon and neuroinflammatory responses to prevent herpes simplex encephalitis onset in mice. Scientific Reports. 11: 21171. PMID 34707143 DOI: 10.1038/s41598-021-00391-7  0.323
2021 Lin YH, Wang H, Fiore A, Förster M, Tung LT, Belle JI, Robert F, Pelletier J, Langlais D, Nijnik A. Loss of MYSM1 inhibits the oncogenic activity of cMYC in B cell lymphoma. Journal of Cellular and Molecular Medicine. PMID 34114734 DOI: 10.1111/jcmm.16554  0.33
2020 Belle JI, Wang H, Fiore A, Petrov JC, Lin YH, Feng CH, Nguyen TTM, Tung J, Campeau PM, Behrends U, Brunet T, Leszinski GS, Gros P, Langlais D, Nijnik A. MYSM1 maintains ribosomal protein gene expression in hematopoietic stem cells to prevent hematopoietic dysfunction. Jci Insight. 5. PMID 32641579 DOI: 10.1172/Jci.Insight.125690  0.464
2020 Fiore A, Liang Y, Lin YH, Tung J, Wang H, Langlais D, Nijnik A. Deubiquitinase MYSM1 in the Hematopoietic System and beyond: A Current Review. International Journal of Molecular Sciences. 21. PMID 32344625 DOI: 10.3390/Ijms21083007  0.436
2019 Jeyakumar T, Fodil N, Van Der Kraak L, Meunier C, Cayrol R, McGregor K, Langlais D, Greenwood CMT, Beauchemin N, Gros P. Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal Cancer. Scientific Reports. 9: 18897. PMID 31827213 DOI: 10.1038/S41598-019-55378-2  0.368
2019 Kennedy JM, Georges A, Bassenden AV, Vidal SM, Berghuis AM, Taniuchi I, Majewski J, Lathrop M, Behr MA, Langlais D, Gros P. ZBTB7B (ThPOK) IS REQUIRED FOR PATHOGENESIS OF CEREBRAL MALARIA AND PROTECTION AGAINST PULMONARY TUBERCULOSIS. Infection and Immunity. PMID 31792077 DOI: 10.1128/Iai.00845-19  0.441
2019 Lin YH, Forster M, Liang Y, Yu M, Wang H, Robert F, Langlais D, Pelletier J, Clare S, Nijnik A. USP44 is dispensable for normal hematopoietic stem cell function, lymphocyte development, and B cell mediated immune response in a mouse model. Experimental Hematology. PMID 30639577 DOI: 10.1016/J.Exphem.2019.01.001  0.43
2018 Kong XF, Martinez-Barricarte R, Kennedy J, Mele F, Lazarov T, Deenick EK, Ma CS, Breton G, Lucero KB, Langlais D, Bousfiha A, Aytekin C, Markle J, Trouillet C, Jabot-Hanin F, et al. Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency. Nature Immunology. PMID 30127434 DOI: 10.1038/S41590-018-0178-Z  0.36
2018 Torre S, Langlais D, Gros P. Genetic analysis of cerebral malaria in the mouse model infected with Plasmodium berghei. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 29922917 DOI: 10.1007/S00335-018-9752-9  0.306
2018 Langlais D, Cencic R, Moradin N, Kennedy JM, Ayi K, Brown LE, Crandall I, Tarry MJ, Schmeing M, Kain KC, Porco JA, Pelletier J, Gros P. Rocaglates as dual-targeting agents for experimental cerebral malaria. Proceedings of the National Academy of Sciences of the United States of America. PMID 29463745 DOI: 10.1073/Pnas.1713000115  0.317
2017 Rojo R, Pridans C, Langlais D, Hume DA. Transcriptional mechanisms that control expression of the macrophage colony-stimulating factor receptor locus. Clinical Science (London, England : 1979). 131: 2161-2182. PMID 28760770 DOI: 10.1042/Cs20170238  0.452
2016 Sheth R, Barozzi I, Langlais D, Osterwalder M, Nemec S, Carlson HL, Stadler HS, Visel A, Drouin J, Kmita M. Distal Limb Patterning Requires Modulation of cis-Regulatory Activities by HOX13. Cell Reports. 17: 2913-2926. PMID 27974206 DOI: 10.1016/J.Celrep.2016.11.039  0.586
2016 Langlais D, Fodil N, Gros P. Genetics of Infectious and Inflammatory Diseases: Overlapping Discoveries from Association and Exome-Sequencing Studies. Annual Review of Immunology. PMID 27912315 DOI: 10.1146/Annurev-Immunol-051116-052442  0.432
2016 Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, et al. USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation. Nature Immunology. PMID 27721430 DOI: 10.1038/Ni.3581  0.425
2016 Langlais D, Barreiro LB, Gros P. The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation. The Journal of Experimental Medicine. PMID 27001747 DOI: 10.1084/Jem.20151764  0.471
2016 Fodil N, Langlais D, Gros P. Primary Immunodeficiencies and Inflammatory Disease: A Growing Genetic Intersection. Trends in Immunology. 37: 126-40. PMID 26791050 DOI: 10.1016/J.It.2015.12.006  0.382
2016 Belle JI, Petrov JC, Langlais D, Robert F, Cencic R, Shen S, Pelletier J, Gros P, Nijnik A. Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance. Cell Death and Differentiation. PMID 26768662 DOI: 10.1038/Cdd.2015.140  0.368
2016 Roussel-Gervais A, Couture C, Langlais D, Takayasu S, Balsalobre A, Rueda BR, Zukerberg LR, Figarella-Branger D, Brue T, Drouin J. The Cables1 Gene in Glucocorticoid Regulation of Pituitary Corticotrope Growth and Cushing Disease. The Journal of Clinical Endocrinology and Metabolism. 101: 513-22. PMID 26695862 DOI: 10.1210/Jc.2015-3324  0.545
2015 Belle JI, Langlais D, Petrov JC, Pardo M, Jones RG, Gros P, Nijnik A. p53 mediates loss of hematopoietic stem cell function and lymphopenia in Mysm1 deficiency. Blood. 125: 2344-8. PMID 25710881 DOI: 10.1182/Blood-2014-05-574111  0.388
2014 Fodil N, Langlais D, Moussa P, Boivin GA, Di Pietrantonio T, Radovanovic I, Dumaine A, Blanchette M, Schurr E, Gros P, Vidal SM. Specific dysregulation of IFNγ production by natural killer cells confers susceptibility to viral infection. Plos Pathogens. 10: e1004511. PMID 25473962 DOI: 10.1371/Journal.Ppat.1004511  0.393
2014 Kennedy JM, Fodil N, Torre S, Bongfen SE, Olivier JF, Leung V, Langlais D, Meunier C, Berghout J, Langat P, Schwartzentruber J, Majewski J, Lathrop M, Vidal SM, Gros P. CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation. The Journal of Experimental Medicine. 211: 2519-35. PMID 25403443 DOI: 10.1084/Jem.20140455  0.453
2014 Salem S, Langlais D, Lefebvre F, Bourque G, Bigley V, Haniffa M, Casanova JL, Burk D, Berghuis A, Butler KM, Leahy TR, Hambleton S, Gros P. Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8(K108E) mutation. Blood. 124: 1894-904. PMID 25122610 DOI: 10.1182/Blood-2014-04-570879  0.38
2014 Radovanovic I, Leung V, Iliescu A, Bongfen SE, Mullick A, Langlais D, Gros P. Genetic control of susceptibility to Candida albicans in SM/J mice. Journal of Immunology (Baltimore, Md. : 1950). 193: 1290-300. PMID 24973457 DOI: 10.4049/Jimmunol.1400783  0.379
2013 Berlivet S, Paquette D, Dumouchel A, Langlais D, Dostie J, Kmita M. Clustering of tissue-specific sub-TADs accompanies the regulation of HoxA genes in developing limbs. Plos Genetics. 9: e1004018. PMID 24385922 DOI: 10.1371/Journal.Pgen.1004018  0.421
2013 Praktiknjo SD, Llamas B, Scott-Boyer MP, Picard S, Robert F, Langlais D, Haibe-Kains B, Faubert D, Silversides DW, Deschepper CF. Novel effects of chromosome Y on cardiac regulation, chromatin remodeling, and neonatal programming in male mice. Endocrinology. 154: 4746-56. PMID 24105479 DOI: 10.1210/En.2013-1699  0.343
2013 Berghout J, Langlais D, Radovanovic I, Tam M, MacMicking JD, Stevenson MM, Gros P. Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria. Plos Pathogens. 9: e1003491. PMID 23853600 DOI: 10.1371/Journal.Ppat.1003491  0.513
2013 Langlais D, Couture C, Kmita M, Drouin J. Adult pituitary cell maintenance: lineage-specific contribution of self-duplication. Molecular Endocrinology (Baltimore, Md.). 27: 1103-12. PMID 23754801 DOI: 10.1210/Me.2012-1407  0.542
2013 Langlais D, Gros P. 155 Cytokine. 63: 279. DOI: 10.1016/J.Cyto.2013.06.158  0.478
2012 Langlais D, Couture C, Balsalobre A, Drouin J. The Stat3/GR interaction code: predictive value of direct/indirect DNA recruitment for transcription outcome. Molecular Cell. 47: 38-49. PMID 22633955 DOI: 10.1016/J.Molcel.2012.04.021  0.586
2011 Marquis JF, Kapoustina O, Langlais D, Ruddy R, Dufour CR, Kim BH, MacMicking JD, Giguère V, Gros P. Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis. Plos Genetics. 7: e1002097. PMID 21731497 DOI: 10.1371/Journal.Pgen.1002097  0.469
2011 Langlais D, Couture C, Sylvain-Drolet G, Drouin J. A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells. Molecular Endocrinology (Baltimore, Md.). 25: 348-59. PMID 21193556 DOI: 10.1210/Me.2010-0422  0.622
2008 Langlais D, Couture C, Balsalobre A, Drouin J. Regulatory network analyses reveal genome-wide potentiation of LIF signaling by glucocorticoids and define an innate cell defense response. Plos Genetics. 4: e1000224. PMID 18927629 DOI: 10.1371/Journal.Pgen.1000224  0.601
Low-probability matches (unlikely to be authored by this person)
2021 Lin YH, Liang Y, Wang H, Tung LT, Förster M, Subramani PG, Di Noia JM, Clare S, Langlais D, Nijnik A. Regulation of B Lymphocyte Development by Histone H2A Deubiquitinase BAP1. Frontiers in Immunology. 12: 626418. PMID 33912157 DOI: 10.3389/fimmu.2021.626418  0.299
2016 Van Der Kraak L, Langlais D, Jothy S, Beauchemin N, Gros P. Mapping hyper-susceptibility to colitis-associated colorectal cancer in FVB/NJ mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 26979842 DOI: 10.1007/S00335-016-9625-Z  0.298
2024 Mousa M, Liang Y, Tung LT, Wang H, Krawczyk C, Langlais D, Nijnik A. Chromatin-binding deubiquitinase MYSM1 acts in haematopoietic progenitors to control dendritic cell development and to program dendritic cell responses to microbial stimulation. Immunology. PMID 38316548 DOI: 10.1111/imm.13758  0.275
2024 Olivier JF, Langlais D, Jeyakumar T, Polyak MJ, Galarneau L, Cayrol R, Jiang H, Molloy KR, Xu G, Suzuki H, LaCava J, Gros P, Fodil N. CCDC88B interacts with RASAL3 and ARHGEF2 and regulates dendritic cell function in neuroinflammation and colitis. Communications Biology. 7: 77. PMID 38200184 DOI: 10.1038/s42003-023-05751-9  0.273
2021 Tung LT, Wang H, Belle JI, Petrov JC, Langlais D, Nijnik A. p53-dependent induction of P2X7 on hematopoietic stem and progenitor cells regulates hematopoietic response to genotoxic stress. Cell Death & Disease. 12: 923. PMID 34625535 DOI: 10.1038/s41419-021-04202-9  0.257
2021 Ramendra R, Mancini M, Ayala JM, Tung LT, Isnard S, Lin J, Routy JP, Nijnik A, Langlais D. Glutathione Metabolism Is a Regulator of the Acute Inflammatory Response of Monocytes to (1→3)-β-D-Glucan. Frontiers in Immunology. 12: 694152. PMID 34858388 DOI: 10.3389/fimmu.2021.694152  0.25
2021 Shen L, Pugsley L, Cencic R, Wang H, Robert F, Naineni SK, Sahni A, Morin G, Zhang W, Nijnik A, Porco JA, Langlais D, Huang S, Pelletier J. A forward genetic screen identifies modifiers of rocaglate responsiveness. Scientific Reports. 11: 18516. PMID 34531456 DOI: 10.1038/s41598-021-97765-8  0.244
2021 Mindt BC, Krisna SS, Duerr CU, Mancini M, Richer L, Vidal SM, Gerondakis S, Langlais D, Fritz JH. The NF-κB Transcription Factor c-Rel Modulates Group 2 Innate Lymphoid Cell Effector Functions and Drives Allergic Airway Inflammation. Frontiers in Immunology. 12: 664218. PMID 34867937 DOI: 10.3389/fimmu.2021.664218  0.237
2021 Rogers D, Sood A, Wang H, van Beek JJP, Rademaker TJ, Artusa P, Schneider C, Shen C, Wong DC, Bhagrath A, Lebel MÈ, Condotta SA, Richer MJ, Martins AJ, Tsang JS, ... ... Langlais D, et al. Pre-existing chromatin accessibility and gene expression differences among naive CD4 T cells influence effector potential. Cell Reports. 37: 110064. PMID 34852223 DOI: 10.1016/j.celrep.2021.110064  0.231
2023 Al-Aubodah TA, Aoudjit L, Pascale G, Perinpanayagam MA, Langlais D, Bitzan M, Samuel SM, Piccirillo CA, Takano T. The extrafollicular B cell response is a hallmark of childhood idiopathic nephrotic syndrome. Nature Communications. 14: 7682. PMID 37996443 DOI: 10.1038/s41467-023-43504-8  0.229
2021 Lévy R, Langlais D, Béziat V, Rapaport F, Rao G, Lazarov T, Bourgey M, Zhou YJ, Briand C, Moriya K, Ailal F, Avery DT, Markle J, Lim AI, Ogishi M, et al. Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents. The Journal of Clinical Investigation. 131. PMID 34623332 DOI: 10.1172/JCI150143  0.227
2019 Jeyakumar T, Fodil N, Van Der Kraak L, Meunier C, Cayrol R, McGregor K, Langlais D, Greenwood C, Beauchemin N, Gros P. P145 INACTIVATION OF IRF1 CAUSES SUSCEPTIBILITY TO COLITIS-ASSOCIATED COLORECTAL CANCER Gastroenterology. 156: S96. DOI: 10.1053/J.Gastro.2019.01.224  0.222
2016 Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, et al. Erratum: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation. Nature Immunology. 17: 1479. PMID 27849203 DOI: 10.1038/ni1216-1479c  0.218
2021 Chan A, Ayala JM, Alvarez F, Piccirillo C, Dong G, Langlais D, Olivier M. The role of Leishmania GP63 in the modulation of innate inflammatory response to Leishmania major infection. Plos One. 16: e0262158. PMID 34972189 DOI: 10.1371/journal.pone.0262158  0.218
2023 Vialard F, Allaeys I, Dong G, Phan MP, Singh U, Hébert MJ, Dieudé M, Langlais D, Boilard E, Labbé DP, Olivier M. Thermoneutrality and severe malaria: investigating the effect of warmer environmental temperatures on the inflammatory response and disease progression. Frontiers in Immunology. 14: 1128466. PMID 37350957 DOI: 10.3389/fimmu.2023.1128466  0.197
2024 Materna M, Delmonte OM, Bosticardo M, Momenilandi M, Conrey PE, Charmeteau-De Muylder B, Bravetti C, Bellworthy R, Cederholm A, Staels F, Ganoza CA, Darko S, Sayed S, Le Floc'h C, Ogishi M, ... ... Langlais D, et al. The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants. Science (New York, N.Y.). 383: eadh4059. PMID 38422122 DOI: 10.1126/science.adh4059  0.185
2022 Lévy R, Gothe F, Momenilandi M, Magg T, Materna M, Peters P, Raedler J, Philippot Q, Rack-Hoch AL, Langlais D, Bourgey M, Lanz AL, Ogishi M, Rosain J, Martin E, et al. Human CARMIL2 deficiency underlies a broader immunological and clinical phenotype than CD28 deficiency. The Journal of Experimental Medicine. 220. PMID 36515678 DOI: 10.1084/jem.20220275  0.182
2020 Yang R, Mele F, Worley L, Langlais D, Rosain J, Benhsaien I, Elarabi H, Croft CA, Doisne JM, Zhang P, Weisshaar M, Jarrossay D, Latorre D, Shen Y, Han J, et al. Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria. Cell. PMID 33296702 DOI: 10.1016/j.cell.2020.10.046  0.172
2022 Psaroudis RT, Singh U, Lora M, Jeon P, Boursiquot A, Stochaj U, Langlais D, Colmegna I. CD26 is a senescence marker associated with reduced immunopotency of human adipose tissue-derived multipotent mesenchymal stromal cells. Stem Cell Research & Therapy. 13: 358. PMID 35883188 DOI: 10.1186/s13287-022-03026-4  0.17
2022 Douanne N, Dong G, Amin A, Bernardo L, Blanchette M, Langlais D, Olivier M, Fernandez-Prada C. Leishmania parasites exchange drug-resistance genes through extracellular vesicles. Cell Reports. 40: 111121. PMID 35858561 DOI: 10.1016/j.celrep.2022.111121  0.161
2022 Butler-Laporte G, Povysil G, Kosmicki JA, Cirulli ET, Drivas T, Furini S, Saad C, Schmidt A, Olszewski P, Korotko U, Quinodoz M, Çelik E, Kundu K, Walter K, Jung J, ... ... Langlais D, et al. Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative. Plos Genetics. 18: e1010367. PMID 36327219 DOI: 10.1371/journal.pgen.1010367  0.158
2021 Ogishi M, Yang R, Aytekin C, Langlais D, Bourgey M, Khan T, Ali FA, Rahman M, Delmonte OM, Chrabieh M, Zhang P, Gruber C, Pelham SJ, Spaan AN, Rosain J, et al. Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child. Nature Medicine. PMID 34183838 DOI: 10.1038/s41591-021-01388-5  0.151
2023 Rosain J, Neehus AL, Manry J, Yang R, Le Pen J, Daher W, Liu Z, Chan YH, Tahuil N, Türel Ö, Bourgey M, Ogishi M, Doisne JM, Izquierdo HM, Shirasaki T, ... ... Langlais D, et al. Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria. Cell. 186: 621-645.e33. PMID 36736301 DOI: 10.1016/j.cell.2022.12.038  0.146
2021 Béziat V, Rapaport F, Hu J, Titeux M, Bonnet des Claustres M, Bourgey M, Griffin H, Bandet É, Ma CS, Sherkat R, Rokni-Zadeh H, Louis DM, Changi-Ashtiani M, Delmonte OM, Fukushima T, ... ... Langlais D, et al. Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy. Cell. PMID 34214472 DOI: 10.1016/j.cell.2021.06.004  0.135
2024 Guérin A, Moncada-Vélez M, Jackson K, Ogishi M, Rosain J, Mancini M, Langlais D, Nunez A, Webster S, Goyette J, Khan T, Marr N, Avery DT, Rao G, Waterboer T, et al. Helper T cell immunity in humans with inherited CD4 deficiency. The Journal of Experimental Medicine. 221. PMID 38557723 DOI: 10.1084/jem.20231044  0.12
2022 Farge D, Loisel S, Resche-Rigon M, Lansiaux P, Colmegna I, Langlais D, Charles C, Pugnet G, Maria ATJ, Chatelus E, Martin T, Hachulla E, Kheav VD, Lambert NC, Wang H, et al. Safety and preliminary efficacy of allogeneic bone marrow-derived multipotent mesenchymal stromal cells for systemic sclerosis: a single-centre, open-label, dose-escalation, proof-of-concept, phase 1/2 study. The Lancet. Rheumatology. 4: e91-e104. PMID 38288741 DOI: 10.1016/S2665-9913(21)00326-X  0.12
2022 Fava VM, Bourgey M, Nawarathna PM, Orlova M, Cassart P, Vinh DC, Cheng MP, Bourque G, Schurr E, Langlais D. A systems biology approach identifies candidate drugs to reduce mortality in severely ill patients with COVID-19. Science Advances. 8: eabm2510. PMID 35648852 DOI: 10.1126/sciadv.abm2510  0.102
2023 Ibarra-Meneses AV, Amin A, Dong G, Olivier M, Langlais D, Fernandez-Prada C. Identification and analysis of the DNA content of small extracellular vesicles isolated from Leishmania parasites. Star Protocols. 4: 102248. PMID 37087735 DOI: 10.1016/j.xpro.2023.102248  0.082
2015 Degnan JR, Böhlke JK, Pelham K, Langlais DM, Walsh GJ. Identification of Groundwater Nitrate Contamination from Explosives Used in Road Construction: Isotopic, Chemical, and Hydrologic Evidence. Environmental Science & Technology. PMID 26709616 DOI: 10.1021/acs.est.5b03671  0.01
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