| Year |
Citation |
Score |
| 2021 |
Galli LM, Anderson MO, Gabriel Fraley J, Sanchez L, Bueno R, Hernandez DN, Maddox EU, Lingappa VR, Burrus LW. Determination of the membrane topology of PORCN, an O-acyl transferase that modifies Wnt signalling proteins. Open Biology. 11: 200400. PMID 34186010 DOI: 10.1098/rsob.200400 |
0.397 |
|
| 2020 |
Marreiros R, Müller-Schiffmann A, Trossbach SV, Prikulis I, Hänsch S, Weidtkamp-Peters S, Moreira AR, Sahu S, Soloviev I, Selvarajah S, Lingappa VR, Korth C. Disruption of cellular proteostasis by H1N1 influenza A virus causes α-synuclein aggregation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32152117 DOI: 10.1073/Pnas.1906466117 |
0.307 |
|
| 2014 |
Marreiros R, Müller-Schiffmann A, Bader V, Selvarajah S, Dey D, Lingappa VR, Korth C. Viral capsid assembly as a model for protein aggregation diseases: Active processes catalyzed by cellular assembly machines comprising novel drug targets. Virus Research. PMID 25451064 DOI: 10.1016/J.Virusres.2014.10.003 |
0.342 |
|
| 2013 |
Lingappa UF, Wu X, Macieik A, Yu SF, Atuegbu A, Corpuz M, Francis J, Nichols C, Calayag A, Shi H, Ellison JA, Harrell EK, Asundi V, Lingappa JR, Prasad MD, ... ... Lingappa VR, et al. Host-rabies virus protein-protein interactions as druggable antiviral targets. Proceedings of the National Academy of Sciences of the United States of America. 110: E861-8. PMID 23404707 DOI: 10.1073/Pnas.1210198110 |
0.377 |
|
| 2013 |
Lingappa VR, Hurt CR, Garvey E. Capsid assembly as a point of intervention for novel anti-viral therapeutics. Current Pharmaceutical Biotechnology. 14: 513-23. PMID 22429134 DOI: 10.2174/13892010113149990201 |
0.331 |
|
| 2012 |
Choi SY, Fogelgren B, Zuo X, Huang L, McKenna S, Lingappa VR, Lipschutz JH. Exocyst Sec10 is involved in basolateral protein translation and translocation in the endoplasmic reticulum. Nephron. Experimental Nephrology. 120: e134-40. PMID 23037926 DOI: 10.1159/000342366 |
0.493 |
|
| 2010 |
Lingappa VR, Harrell E, Copeland K, Prasad MD, Asundi V, Hahner N, Francis J, Dey D, Welsh J, Macieik A, Lingappa JR, Kelleher C, Hurt CR, Hansen W. Cell-Free Protein Synthesizing Systems As Tools for Discovery of Drugs Inhibiting Viral Capsid Assembly Antiviral Research. 86: A61. DOI: 10.1016/J.Antiviral.2010.02.453 |
0.318 |
|
| 2010 |
Copeland K, Hansen W, Asundi V, Hong S, Chamberlin J, Dey D, Broce S, Himmel H, Decloutte C, Ram S, Steffen I, Pöhlmann S, Lingappa JR, Hurt CR, Lingappa VR. Protein–Protein Interactions Occurring During HIV Capsid Assembly in a Cell-free Protein Synthesizing System Antiviral Research. 86: A22. DOI: 10.1016/J.Antiviral.2010.02.339 |
0.313 |
|
| 2007 |
Ott CM, Akhavan A, Lingappa VR. Specific features of the prion protein transmembrane domain regulate nascent chain orientation. The Journal of Biological Chemistry. 282: 11163-71. PMID 17276986 DOI: 10.1074/Jbc.M607660200 |
0.672 |
|
| 2004 |
Ott CM, Lingappa VR. Signal sequences influence membrane integration of the prion protein. Biochemistry. 43: 11973-82. PMID 15379537 DOI: 10.1021/Bi049156S |
0.723 |
|
| 2003 |
Rutkowski DT, Ott CM, Polansky JR, Lingappa VR. Signal sequences initiate the pathway of maturation in the endoplasmic reticulum lumen. The Journal of Biological Chemistry. 278: 30365-72. PMID 12771148 DOI: 10.1074/Jbc.M302117200 |
0.774 |
|
| 2003 |
Lipschutz JH, Lingappa VR, Mostov KE. The exocyst affects protein synthesis by acting on the translocation machinery of the endoplasmic reticulum. The Journal of Biological Chemistry. 278: 20954-60. PMID 12665531 DOI: 10.1074/Jbc.M213210200 |
0.633 |
|
| 2002 |
Bose HS, Lingappa VR, Miller WL. The steroidogenic acute regulatory protein, StAR, works only at the outer mitochondrial membrane. Endocrine Research. 28: 295-308. PMID 12530629 DOI: 10.1081/Erc-120016800 |
0.352 |
|
| 2002 |
Lingappa VR, Rutkowski DT, Hegde RS, Andersen OS. Conformational control through translocational regulation: a new view of secretory and membrane protein folding. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 24: 741-8. PMID 12210535 DOI: 10.1002/Bies.10130 |
0.785 |
|
| 2002 |
Bose HS, Lingappa VR, Miller WL. Rapid regulation of steroidogenesis by mitochondrial protein import. Nature. 417: 87-91. PMID 11986670 DOI: 10.1038/417087A |
0.402 |
|
| 2002 |
Ott CM, Lingappa VR. Integral membrane protein biosynthesis: why topology is hard to predict. Journal of Cell Science. 115: 2003-9. PMID 11973342 |
0.707 |
|
| 2001 |
Rutkowski DT, Lingappa VR, Hegde RS. Substrate-specific regulation of the ribosome- translocon junction by N-terminal signal sequences. Proceedings of the National Academy of Sciences of the United States of America. 98: 7823-8. PMID 11416167 DOI: 10.1073/Pnas.141125098 |
0.78 |
|
| 1999 |
Hegde RS, Tremblay P, Groth D, DeArmond SJ, Prusiner SB, Lingappa VR. Transmissible and genetic prion diseases share a common pathway of neurodegeneration. Nature. 402: 822-6. PMID 10617204 DOI: 10.1038/45574 |
0.564 |
|
| 1999 |
Hegde RS, Lingappa VR. Regulation of protein biogenesis at the endoplasmic reticulum membrane. Trends in Cell Biology. 9: 132-7. PMID 10203789 DOI: 10.1016/S0962-8924(99)01504-4 |
0.698 |
|
| 1998 |
Hegde RS, Voigt S, Lingappa VR. Regulation of protein topology by trans-acting factors at the endoplasmic reticulum. Molecular Cell. 2: 85-91. PMID 9702194 DOI: 10.1016/S1097-2765(00)80116-1 |
0.685 |
|
| 1998 |
Rusiñol AE, Hegde RS, Chuck SL, Lingappa VR, Vance JE. Translocational pausing of apolipoprotein B can be regulated by membrane lipid composition. Journal of Lipid Research. 39: 1287-94. PMID 9643361 |
0.341 |
|
| 1998 |
Hegde RS, Voigt S, Rapoport TA, Lingappa VR. TRAM regulates the exposure of nascent secretory proteins to the cytosol during translocation into the endoplasmic reticulum. Cell. 92: 621-31. PMID 9506517 DOI: 10.1016/S0092-8674(00)81130-7 |
0.691 |
|
| 1998 |
Hegde RS, Mastrianni JA, Scott MR, DeFea KA, Tremblay P, Torchia M, DeArmond SJ, Prusiner SB, Lingappa VR. A transmembrane form of the prion protein in neurodegenerative disease. Science (New York, N.Y.). 279: 827-34. PMID 9452375 DOI: 10.1126/Science.279.5352.827 |
0.612 |
|
| 1997 |
Hegde RS, Lingappa VR. Membrane protein biogenesis: regulated complexity at the endoplasmic reticulum. Cell. 91: 575-82. PMID 9393851 DOI: 10.1016/S0092-8674(00)80445-6 |
0.669 |
|
| 1997 |
Kivlen MH, Dorsey CA, Lingappa VR, Hegde RS. Asymmetric distribution of pause transfer sequences in apolipoprotein B-100. Journal of Lipid Research. 38: 1149-62. PMID 9215543 |
0.366 |
|
| 1996 |
Hegde RS, Lingappa VR. Sequence-specific alteration of the ribosome-membrane junction exposes nascent secretory proteins to the cytosol. Cell. 85: 217-28. PMID 8612274 DOI: 10.1016/S0092-8674(00)81098-3 |
0.692 |
|
| 1994 |
Nakahara DH, Lingappa VR, Chuck SL. Translocational pausing is a common step in the biogenesis of unconventional integral membrane and secretory proteins. The Journal of Biological Chemistry. 269: 7617-22. PMID 8125986 |
0.499 |
|
| 1994 |
De Fea KA, Nakahara DH, Calayag MC, Yost CS, Mirels LF, Prusiner SB, Lingappa VR. Determinants of carboxyl-terminal domain translocation during prion protein biogenesis. The Journal of Biological Chemistry. 269: 16810-20. PMID 7911469 |
0.511 |
|
| 1994 |
Skach WR, Lingappa VR. Transmembrane orientation and topogenesis of the third and fourth membrane-spanning regions of human P-glycoprotein (MDR1). Cancer Research. 54: 3202-9. PMID 7911395 |
0.689 |
|
| 1994 |
Lingappa JR, Martin RL, Wong ML, Ganem D, Welch WJ, Lingappa VR. A eukaryotic cytosolic chaperonin is associated with a high molecular weight intermediate in the assembly of hepatitis B virus capsid, a multimeric particle. The Journal of Cell Biology. 125: 99-111. PMID 7908022 DOI: 10.1083/Jcb.125.1.99 |
0.327 |
|
| 1994 |
Skach WR, Shi LB, Calayag MC, Frigeri A, Lingappa VR, Verkman AS. Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum. The Journal of Cell Biology. 125: 803-15. PMID 7514605 DOI: 10.1083/Jcb.125.4.803 |
0.735 |
|
| 1994 |
Rusin˜ol A, Chuck S, Lingappa V, Vance J. Regulation of translocation of apolipoprotein B across the ER membrane by a ‘pause-transfer’ sequence and membrane lipid composition Atherosclerosis. 109: 137-138. DOI: 10.1016/0021-9150(94)93561-0 |
0.337 |
|
| 1993 |
Chuck SL, Lingappa VR. Analysis of a pause transfer sequence from apolipoprotein B. The Journal of Biological Chemistry. 268: 22794-801. PMID 8226789 |
0.307 |
|
| 1993 |
Skach WR, Calayag MC, Lingappa VR. Evidence for an alternate model of human P-glycoprotein structure and biogenesis. The Journal of Biological Chemistry. 268: 6903-8. PMID 8096508 |
0.651 |
|
| 1993 |
Skach WR, Lingappa VR. Amino-terminal assembly of human P-glycoprotein at the endoplasmic reticulum is directed by cooperative actions of two internal sequences. The Journal of Biological Chemistry. 268: 23552-61. PMID 7901209 |
0.73 |
|
| 1992 |
Chuck SL, Lingappa VR. Pause transfer: a topogenic sequence in apolipoprotein B mediates stopping and restarting of translocation. Cell. 68: 9-21. PMID 1370657 DOI: 10.1016/0092-8674(92)90202-N |
0.371 |
|
| 1992 |
Hasegawa H, Skach W, Baker O, Calayag MC, Lingappa V, Verkman AS. A multifunctional aqueous channel formed by CFTR. Science (New York, N.Y.). 258: 1477-9. PMID 1279809 DOI: 10.1126/Science.1279809 |
0.592 |
|
| 1991 |
Frey BM, Frey FJ, Lingappa VR, Trachsel H. Expression of human recombinant lipocortin I in a wheat-germ cell-free system and Xenopus oocytes. Lipocortin is not secreted. The Biochemical Journal. 275: 219-25. PMID 1826832 |
0.466 |
|
| 1991 |
Lingappa VR. Control of protein topology at the endoplasmic reticulum. Cell Biophysics. 19: 1-15. PMID 1726880 DOI: 10.1007/BF02989874 |
0.439 |
|
| 1991 |
Lingappa VR. More than just a channel: provocative new features of protein traffic across the ER membrane. Cell. 65: 527-30. PMID 1709589 DOI: 10.1016/0092-8674(91)90081-9 |
0.532 |
|
| 1990 |
Chuck SL, Yao Z, Blackhart BD, McCarthy BJ, Lingappa VR. New variation on the translocation of proteins during early biogenesis of apolipoprotein B. Nature. 346: 382-5. PMID 2374610 DOI: 10.1038/346382A0 |
0.439 |
|
| 1990 |
Eble BE, Lingappa VR, Ganem D. The N-terminal (pre-S2) domain of a hepatitis B virus surface glycoprotein is translocated across membranes by downstream signal sequences. Journal of Virology. 64: 1414-9. PMID 2304150 DOI: 10.1128/Jvi.64.3.1414-1419.1990 |
0.425 |
|
| 1990 |
Lopez CD, Yost CS, Prusiner SB, Myers RM, Lingappa VR. Unusual topogenic sequence directs prion protein biogenesis. Science (New York, N.Y.). 248: 226-9. PMID 1970195 DOI: 10.1126/Science.1970195 |
0.507 |
|
| 1990 |
Yost CS, Lopez CD, Prusiner SB, Myers RM, Lingappa VR. Non-hydrophobic extracytoplasmic determinant of stop transfer in the prion protein. Nature. 343: 669-72. PMID 1968226 DOI: 10.1038/343669A0 |
0.528 |
|
| 1989 |
Andrews DW, Lauffer L, Walter P, Lingappa VR. Evidence for a two-step mechanism involved in assembly of functional signal recognition particle receptor. The Journal of Cell Biology. 108: 797-810. PMID 2537835 DOI: 10.1083/Jcb.108.3.797 |
0.592 |
|
| 1988 |
Simon K, Lingappa VR, Ganem D. A block to the intracellular transport and assembly of hepatitis B surface antigen polypeptides in Xenopus oocytes. Virology. 166: 76-81. PMID 3413987 DOI: 10.1016/0042-6822(88)90148-1 |
0.313 |
|
| 1988 |
Simon K, Lingappa VR, Ganem D. Secreted hepatitis B surface antigen polypeptides are derived from a transmembrane precursor. The Journal of Cell Biology. 107: 2163-8. PMID 3198683 DOI: 10.1083/Jcb.107.6.2163 |
0.421 |
|
| 1988 |
Andrews DW, Perara E, Lesser C, Lingappa VR. Sequences beyond the cleavage site influence signal peptide function. The Journal of Biological Chemistry. 263: 15791-8. PMID 3170612 |
0.414 |
|
| 1988 |
Rothman RE, Andrews DW, Calayag MC, Lingappa VR. Construction of defined polytopic integral transmembrane proteins. The role of signal and stop transfer sequence permutations. The Journal of Biological Chemistry. 263: 10470-80. PMID 2839492 |
0.478 |
|
| 1987 |
Eble BE, MacRae DR, Lingappa VR, Ganem D. Multiple topogenic sequences determine the transmembrane orientation of the hepatitis B surface antigen. Molecular and Cellular Biology. 7: 3591-601. PMID 3683395 DOI: 10.1128/Mcb.7.10.3591 |
0.446 |
|
| 1987 |
Simon K, Perara E, Lingappa VR. Translocation of globin fusion proteins across the endoplasmic reticulum membrane in Xenopus laevis oocytes. The Journal of Cell Biology. 104: 1165-72. PMID 3553206 DOI: 10.1083/Jcb.104.5.1165 |
0.514 |
|
| 1987 |
Hay B, Barry RA, Lieberburg I, Prusiner SB, Lingappa VR. Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein [published errratum appears in Mol Cell Biol 1987 May;7(5):2035]. Molecular and Cellular Biology. 7: 914-20. PMID 3547085 DOI: 10.1128/Mcb.7.2.914 |
0.493 |
|
| 1987 |
Hay B, Prusiner SB, Lingappa VR. Evidence for a secretory form of the cellular prion protein. Biochemistry. 26: 8110-5. PMID 3126796 DOI: 10.1021/Bi00399A014 |
0.493 |
|
| 1986 |
Perara E, Rothman RE, Lingappa VR. Uncoupling translocation from translation: implications for transport of proteins across membranes. Science (New York, N.Y.). 232: 348-52. PMID 3961485 |
0.42 |
|
| 1986 |
Mize NK, Andrews DW, Lingappa VR. A stop transfer sequence recognizes receptors for nascent chain translocation across the endoplasmic reticulum membrane. Cell. 47: 711-9. PMID 3096576 DOI: 10.1016/0092-8674(86)90514-3 |
0.553 |
|
| 1986 |
Walter P, Lingappa VR. Mechanism of protein translocation across the endoplasmic reticulum membrane. Annual Review of Cell Biology. 2: 499-516. PMID 3030381 DOI: 10.1146/Annurev.Cb.02.110186.002435 |
0.572 |
|
| 1986 |
Eble BE, Lingappa VR, Ganem D. Hepatitis B surface antigen: an unusual secreted protein initially synthesized as a transmembrane polypeptide. Molecular and Cellular Biology. 6: 1454-63. PMID 3023891 DOI: 10.1128/Mcb.6.5.1454 |
0.435 |
|
| 1986 |
Bray PF, Rosa JP, Lingappa VR, Kan YW, McEver RP, Shuman MA. Biogenesis of the platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa. Proceedings of the National Academy of Sciences of the United States of America. 83: 1480-4. PMID 3006053 DOI: 10.1073/Pnas.83.5.1480 |
0.395 |
|
| 1985 |
Perara E, Lingappa VR. A former amino terminal signal sequence engineered to an internal location directs translocation of both flanking protein domains. The Journal of Cell Biology. 101: 2292-301. PMID 3864782 |
0.483 |
|
| 1984 |
Lingappa VR, Chaidez J, Yost CS, Hedgpeth J. Determinants for protein localization: beta-lactamase signal sequence directs globin across microsomal membranes. Proceedings of the National Academy of Sciences of the United States of America. 81: 456-60. PMID 6607473 DOI: 10.1073/Pnas.81.2.456 |
0.431 |
|
| 1983 |
Yost CS, Hedgpeth J, Lingappa VR. A stop transfer sequence confers predictable transmembrane orientation to a previously secreted protein in cell-free systems. Cell. 34: 759-66. PMID 6313206 DOI: 10.1016/0092-8674(83)90532-9 |
0.577 |
|
| 1980 |
Lingappa VR, Blobel G. Early events in the biosynthesis of secretory and membrane proteins: the signal hypothesis. Recent Progress in Hormone Research. 36: 451-75. PMID 6997945 DOI: 10.1016/B978-0-12-571136-4.50018-8 |
0.656 |
|
| 1980 |
Lingappa VR, Lingappa JR, Blobel G. Signal sequences for early events in protein secretion and membrane assembly. Annals of the New York Academy of Sciences. 343: 356-61. PMID 6994554 DOI: 10.1111/J.1749-6632.1980.Tb47264.X |
0.683 |
|
| 1980 |
McCune JM, Lingappa VR, Fu SM, Blobel G, Kunkel HG. Biogenesis of membrane-bound and secreted immunoglobulins. I. Two distinct translation products of human mu-chain, with identical N-termini and different C-termini. The Journal of Experimental Medicine. 152: 463-8. PMID 6772735 DOI: 10.1084/Jem.152.2.463 |
0.513 |
|
| 1979 |
Blobel G, Walter P, Chang CN, Goldman BM, Erickson AH, Lingappa VR. Translocation of proteins across membranes: the signal hypothesis and beyond. Symposia of the Society For Experimental Biology. 33: 9-36. PMID 524275 |
0.694 |
|
| 1979 |
Lingappa VR, Lingappa JR, Blobel G. Chicken ovalbumin contains an internal signal sequence. Nature. 281: 117-21. PMID 471058 DOI: 10.1038/281117A0 |
0.628 |
|
| 1979 |
Walter P, Jackson RC, Marcus MM, Lingappa VR, Blobel G. Tryptic dissection and reconstitution of translocation activity for nascent presecretory proteins across microsomal membranes. Proceedings of the National Academy of Sciences of the United States of America. 76: 1795-9. PMID 109833 DOI: 10.1073/Pnas.76.4.1795 |
0.689 |
|
| 1979 |
Lingappa VR, Cunningham BA, Jazwinski SM, Hopp TP, Blobel G, Edelman GM. Cell-free synthesis and segregation of beta 2-microglobulin. Proceedings of the National Academy of Sciences of the United States of America. 76: 3651-5. PMID 91168 DOI: 10.1073/Pnas.76.8.3651 |
0.594 |
|
| 1978 |
Lingappa VR, Shields D, Woo SL, Blobel G. Nascent chicken ovalbumin contains the functional equivalent of a signal sequence. The Journal of Cell Biology. 79: 567-72. PMID 569160 DOI: 10.1083/Jcb.79.2.567 |
0.629 |
|
| 1978 |
Lingappa VR, Lingappa JR, Prasad R, Ebner KE, Blobel G. Coupled cell-free synthesis, segregation, and core glycosylation of a secretory protein. Proceedings of the National Academy of Sciences of the United States of America. 75: 2338-42. PMID 276877 DOI: 10.1073/Pnas.75.5.2338 |
0.594 |
|
| 1978 |
Lingappa VR, Katz FN, Lodish HF, Blobel G. A signal sequence for the insertion of a transmembrane glycoprotein. Similarities to the signals of secretory proteins in primary structure and function. The Journal of Biological Chemistry. 253: 8667-70. PMID 214427 |
0.67 |
|
| 1977 |
Lingappa VR, Devillers-Thiery A, Blobel G. Nascent prehormones are intermediates in the biosynthesis of authentic bovine pituitary growth hormone and prolactin. Proceedings of the National Academy of Sciences of the United States of America. 74: 2432-6. PMID 267936 DOI: 10.1073/Pnas.74.6.2432 |
0.565 |
|
| 1977 |
Katz FN, Rothman JE, Lingappa VR, Blobel G, Lodish HF. Membrane assembly in vitro: synthesis, glycosylation, and asymmetric insertion of a transmembrane protein. Proceedings of the National Academy of Sciences of the United States of America. 74: 3278-82. PMID 198778 DOI: 10.1073/Pnas.74.8.3278 |
0.642 |
|
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