Year |
Citation |
Score |
2022 |
Kim G, Nakayama L, Blum JA, Akiyama T, Boeynaems S, Chakraborty M, Couthouis J, Tassoni-Tsuchida E, Rodriguez CM, Bassik MC, Gitler AD. Genome-wide CRISPR screen reveals v-ATPase as a drug target to lower levels of ALS protein ataxin-2. Cell Reports. 41: 111508. PMID 36288714 DOI: 10.1016/j.celrep.2022.111508 |
0.305 |
|
2022 |
Vest RT, Chou CC, Zhang H, Haney MS, Li L, Laqtom NN, Chang B, Shuken S, Nguyen A, Yerra L, Yang AC, Green C, Tanga M, Abu-Remaileh M, Bassik MC, et al. Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 119: e2121609119. PMID 35259016 DOI: 10.1073/pnas.2121609119 |
0.711 |
|
2020 |
Marschallinger J, Iram T, Zardeneta M, Lee SE, Lehallier B, Haney MS, Pluvinage JV, Mathur V, Hahn O, Morgens DW, Kim J, Tevini J, Felder TK, Wolinski H, Bertozzi CR, ... Bassik MC, et al. Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain. Nature Neuroscience. PMID 32719564 DOI: 10.1038/s41593-020-0682-y |
0.661 |
|
2020 |
Marschallinger J, Iram T, Zardeneta M, Lee SE, Lehallier B, Haney MS, Pluvinage JV, Mathur V, Hahn O, Morgens DW, Kim J, Tevini J, Felder TK, Wolinski H, Bertozzi CR, ... Bassik MC, et al. Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain. Nature Neuroscience. PMID 32005940 DOI: 10.1038/S41593-020-0595-9 |
0.661 |
|
2020 |
Marschallinger J, Iram T, Zardeneta M, Lee SE, Lehallier B, Haney MS, Pluvinage JV, Mathur V, Hahn O, Morgens DW, Kim J, Tevini J, Felder TK, Wolinski H, Bertozzi CR, ... Bassik MC, et al. Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain. Nature Neuroscience. PMID 31959936 DOI: 10.1038/S41593-019-0566-1 |
0.707 |
|
2020 |
Wojcicki A, Chae H, Han K, Youn M, Wilkes MC, Lacayo NJ, Bassik M, Sakamoto KM. Genetic Modulators of Niclosamide Sensitivity and Resistance in Acute Myeloid Leukemia Blood. 136: 29-29. DOI: 10.1182/BLOOD-2020-137340 |
0.346 |
|
2020 |
Kostyrko K, Kelly M, Han K, Jeng E, Morgens D, Bassik M, Jackson P, Sweet-Cordero A. Abstract PR07: Combinatorial knockout of Rap1GDS1 and RhoA leads to lethality in KRAS-driven non-small cell lung cancer Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Ras18-Pr07 |
0.411 |
|
2019 |
Chai N, Haney MS, Couthouis J, Morgens DW, Benjamin A, Wu K, Ousey J, Fang S, Finer S, Bassik MC, Gitler AD. Genome-wide synthetic lethal CRISPR screen identifies FIS1 as a genetic interactor of ALS-linked C9ORF72. Brain Research. 146601. PMID 31843624 DOI: 10.1016/J.Brainres.2019.146601 |
0.662 |
|
2019 |
Cheng W, Wang S, Zhang Z, Morgens DW, Hayes LR, Lee S, Portz B, Xie Y, Nguyen BV, Haney MS, Yan S, Dong D, Coyne AN, Yang J, Xian F, ... ... Bassik MC, et al. CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation. Neuron. PMID 31587919 DOI: 10.1016/J.Neuron.2019.09.003 |
0.635 |
|
2019 |
Prolo LM, Li A, Owen SF, Parker JJ, Foshay K, Nitta RT, Morgens DW, Bolin S, Wilson CM, Vega L JCM, Luo EJ, Nwagbo G, Waziri A, Li G, Reimer RJ, ... Bassik MC, et al. Targeted genomic CRISPR-Cas9 screen identifies MAP4K4 as essential for glioblastoma invasion. Scientific Reports. 9: 14020. PMID 31570734 DOI: 10.1038/s41598-019-50160-w |
0.32 |
|
2019 |
Li J, Khankan RR, Caneda C, Godoy MI, Haney MS, Krawczyk MC, Bassik MC, Sloan SA, Zhang Y. Astrocyte-to-astrocyte contact and a positive feedback loop of growth factor signaling regulate astrocyte maturation. Glia. PMID 31033049 DOI: 10.1002/Glia.23630 |
0.614 |
|
2019 |
Pluvinage JV, Haney MS, Smith BAH, Sun J, Iram T, Bonanno L, Li L, Lee DP, Morgens DW, Yang AC, Shuken SR, Gate D, Scott M, Khatri P, Luo J, ... ... Bassik MC, et al. CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. Nature. PMID 30944478 DOI: 10.1038/S41586-019-1088-4 |
0.684 |
|
2019 |
Kelly MR, Han K, Kostyrko K, Jeng EE, Mooney N, Sweet-Cordero A, Bassik M, Jackson PK. Abstract 959: Proteomic and genetic interaction mapping of the Ras pathway reveals new effectors and vulnerabilities Cancer Research. 79: 959-959. DOI: 10.1158/1538-7445.Am2019-959 |
0.306 |
|
2018 |
Haney MS, Bohlen CJ, Morgens DW, Ousey JA, Barkal AA, Tsui CK, Ego BK, Levin R, Kamber RA, Collins H, Tucker A, Li A, Vorselen D, Labitigan L, Crane E, ... ... Bassik MC, et al. Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens. Nature Genetics. PMID 30397336 DOI: 10.1038/S41588-018-0254-1 |
0.66 |
|
2018 |
Duque-Afonso J, Lin CH, Han K, Morgens DW, Jeng EE, Weng Z, Jeong J, Wong SHK, Zhu L, Wei MC, Chae HD, Schrappe M, Cario G, Duyster J, Sakamoto KM, ... Bassik MC, et al. CBP modulates sensitivity to dasatinib in pre-BCR+ acute lymphoblastic leukemia. Cancer Research. PMID 30262461 DOI: 10.1158/0008-5472.Can-18-1703 |
0.633 |
|
2018 |
Kramer NJ, Haney MS, Morgens DW, Jovičić A, Couthouis J, Li A, Ousey J, Ma R, Bieri G, Tsui CK, Shi Y, Hertz NT, Tessier-Lavigne M, Ichida JK, Bassik MC, et al. CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. Nature Genetics. PMID 29507424 DOI: 10.1038/S41588-018-0070-7 |
0.657 |
|
2018 |
Shukla N, Salahudeen AA, de la O S, Hart DJ, Taylor G, Zhu J, Yuki K, Seoane J, Ma Z, Ding J, Han K, Morgens D, Bassik M, Curtis C, Kuo CJ. Identification and validation of a novel drug target in an organoid model of esophageal cancer. Journal of Clinical Oncology. 36: 46-46. DOI: 10.1200/Jco.2018.36.4_Suppl.46 |
0.35 |
|
2018 |
Kelly MR, Han K, Mooney N, Jeng E, Kostyrko K, Sweet-Cordero A, Bassik M, Jackson PK. Abstract PR12: A combined protein-protein interaction and genetic interaction map defines new and critical Kras effectors in non-small cell lung cancer Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-Pr12 |
0.405 |
|
2017 |
Morgens DW, Wainberg M, Boyle EA, Ursu O, Araya CL, Tsui CK, Haney MS, Hess GT, Han K, Jeng EE, Li A, Snyder MP, Greenleaf WJ, Kundaje A, Bassik MC. Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens. Nature Communications. 8: 15178. PMID 28474669 DOI: 10.1038/Ncomms15178 |
0.652 |
|
2017 |
Hart DJ, Salahudeen AA, O Sdl, Han K, Morgens D, Bassik M, Kuo CJ. Rapid characterization of candidate loss of function genes in primary organoid culture. Journal of Clinical Oncology. 35: 77-77. DOI: 10.1200/Jco.2017.35.4_Suppl.77 |
0.321 |
|
2017 |
Han K, Jeng E, Hess G, Morgens D, Li A, Bassik M. Abstract PR04: A CRISPR-based genetic interaction map identifies synergistic drug combinations for cancer Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-Pr04 |
0.336 |
|
2017 |
Prolo LM, Li A, Morgens D, Reimer R, Bassik M, Grant GA. 137 Novel Genome-wide CRISPR Screen for Glioblastoma Invasion Neurosurgery. 64: 232-232. DOI: 10.1093/Neuros/Nyx417.137 |
0.407 |
|
2016 |
Duque-Afonso J, Lin CH, Han K, Wei MC, Feng J, Kurzer J, Schneidawind C, Wong SH, Bassik MC, Cleary ML. E2A-PBX1 remodels oncogenic signaling networks in B-cell precursor acute lymphoid leukemia. Cancer Research. PMID 27758892 DOI: 10.1158/0008-5472.Can-16-1899 |
0.638 |
|
2015 |
Kampmann M, Horlbeck MA, Chen Y, Tsai JC, Bassik MC, Gilbert LA, Villalta JE, Kwon SC, Chang H, Kim VN, Weissman JS. Next-generation libraries for robust RNA interference-based genome-wide screens. Proceedings of the National Academy of Sciences of the United States of America. 112: E3384-91. PMID 26080438 DOI: 10.1073/Pnas.1508821112 |
0.311 |
|
2015 |
Duque-Afonso J, Wei MC, Lin C, Feng J, Buechele C, Wong SH, Bassik MC, Cleary ML. Oncogenic Role for the Lck/ZAP70/PLCG2 Signaling Pathway in Pre-B-ALL Pathogenesis Blood. 126: 810-810. DOI: 10.1182/Blood.V126.23.810.810 |
0.639 |
|
2014 |
Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS. Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Cell. 159: 647-61. PMID 25307932 DOI: 10.1016/J.Cell.2014.09.029 |
0.326 |
|
2014 |
van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, Hoeben RC, LeProust EM, Chen S, Hoelen H, Ressing ME, Patena W, Weissman JS, McManus MT, Wiertz EJ, et al. A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation. Nature Communications. 5: 3832. PMID 24807418 DOI: 10.1038/Ncomms4832 |
0.682 |
|
2013 |
Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML. Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens. Chemistry & Biology. 20: 1352-63. PMID 24183972 DOI: 10.1016/J.Chembiol.2013.09.014 |
0.72 |
|
2013 |
Kampmann M, Bassik MC, Weissman JS. Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E2317-26. PMID 23739767 DOI: 10.1073/Pnas.1307002110 |
0.304 |
|
2013 |
Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell. 152: 909-22. PMID 23394947 DOI: 10.1016/J.Cell.2013.01.030 |
0.688 |
|
2013 |
Wei MC, Matheny CJ, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley D, Rau RE, Brown P, McManus MT, Weissman JS, Cleary ML. Next-Generation NAMPT Inhibitors For ALL Identified By Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens Blood. 122: 171-171. DOI: 10.1182/Blood.V122.21.171.171 |
0.733 |
|
2013 |
Acosta-Alvear D, Kampmann M, Bassik MC, Lee CP, Cho MY, Aftab BT, Li X, Gestwicki JE, Shuman MA, Weissman JS, Walter P. Abstract C01: Systematic blueprinting of genetic vulnerabilities using ultra-complex shRNA libraries identifies genes synergizing with proteasome inhibition or blockade of IRE1 in multiple myeloma cells Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-C01 |
0.328 |
|
2013 |
Kampmann M, Acosta-Alvear D, Bassik MC, Chen Y, Walter P, Weissman JS. Abstract PR06: Systematic genetic interaction maps reveal synthetic-lethal vulnerabilities in leukemia and multiple myeloma Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-Pr06 |
0.3 |
|
2013 |
Acosta-Alvear D, Kampmann M, Bassik MC, Lee CP, Shuman MA, Weissman JS, Walter P. Abstract A08: Systematic identification of genetic vulnerabilities synergizing with proteasome and IRE1 inhibition in multiple myeloma cells using ultra-complex shRNA libraries Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-A08 |
0.311 |
|
2013 |
He C, Bassik MC, Moresi V, Sun K, Wei Y, Zou Z, An Z, Loh J, Fisher J, Sun Q, Korsmeyer S, Packer M, May HI, Hill JA, Virgin HW, et al. Erratum: Corrigendum: Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis Nature. 503: 146-146. DOI: 10.1038/Nature12747 |
0.404 |
|
2012 |
He C, Bassik MC, Moresi V, Sun K, Wei Y, Zou Z, An Z, Loh J, Fisher J, Sun Q, Korsmeyer S, Packer M, May HI, Hill JA, Virgin HW, et al. Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature. 481: 511-5. PMID 22258505 DOI: 10.1038/Nature10758 |
0.44 |
|
2009 |
Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT. Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nature Methods. 6: 443-5. PMID 19448642 DOI: 10.1038/Nmeth.1330 |
0.732 |
|
2008 |
Wei Y, Pattingre S, Sinha S, Bassik M, Levine B. JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy Molecular Cell. 30: 678-688. PMID 18570871 DOI: 10.1016/J.Molcel.2008.06.001 |
0.328 |
|
2006 |
Lin SS, Bassik MC, Suh H, Nishino M, Arroyo JD, Hahn WC, Korsmeyer SJ, Roberts TM. PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum Journal of Biological Chemistry. 281: 23003-23012. PMID 16717086 DOI: 10.1074/Jbc.M602648200 |
0.476 |
|
2006 |
Hetz C, Bernasconi P, Fisher J, Lee AH, Bassik MC, Antonsson B, Brandt GS, Iwakoshi NN, Schrinzel A, Glimcher LH, Korsmeyer SJ. Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1α Science. 312: 572-576. PMID 16645094 DOI: 10.1126/Science.1123480 |
0.479 |
|
2005 |
Oakes SA, Scorrano L, Opferman JT, Bassik MC, Nishino M, Pozzan T, Korsmeyer SJ. Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America. 102: 105-10. PMID 15613488 DOI: 10.1073/Pnas.0408352102 |
0.431 |
|
2004 |
Bassik MC, Scorrano L, Oakes SA, Pozzan T, Korsmeyer SJ. Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis. The Embo Journal. 23: 1207-16. PMID 15010700 DOI: 10.1038/Sj.Emboj.7600104 |
0.432 |
|
2002 |
Letai A, Bassik MC, Walensky LD, Sorcinelli MD, Weiler S, Korsmeyer SJ. Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics Cancer Cell. 2: 183-192. PMID 12242151 DOI: 10.1016/S1535-6108(02)00127-7 |
0.431 |
|
2000 |
Gross A, Pilcher K, Blachly-Dyson E, Basso E, Jockel J, Bassik MC, Korsmeyer SJ, Forte M. Biochemical and genetic analysis of the mitochondrial response of yeast to BAX and BCL-X(L) Molecular and Cellular Biology. 20: 3125-3136. PMID 10757797 DOI: 10.1128/Mcb.20.9.3125-3136.2000 |
0.453 |
|
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