Laura Finzi, Ph.D. - Publications

Affiliations: 
Emory University, Atlanta, GA 

89 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Qian J, Wang B, Artsimovitch I, Dunlap D, Finzi L. Force and the α-C-terminal domains bias RNA polymerase recycling. Nature Communications. 15: 7520. PMID 39214958 DOI: 10.1038/s41467-024-51603-3  0.341
2023 Collette D, Dunlap D, Finzi L. Macromolecular Crowding and DNA: Bridging the Gap between In Vitro and In Vivo. International Journal of Molecular Sciences. 24. PMID 38139331 DOI: 10.3390/ijms242417502  0.436
2023 Qian J, Collette D, Finzi L, Dunlap D. Detecting DNA Loops Using Tethered Particle Motion. Methods in Molecular Biology (Clifton, N.J.). 2694: 451-466. PMID 37824017 DOI: 10.1007/978-1-0716-3377-9_21  0.393
2023 Qian J, Cartee AG, Dunlap D, Artsimovitch I, Finzi L. Transcription Through Roadblock Systems Reveals A Hybrid Transit Mechanism. Biorxiv : the Preprint Server For Biology. PMID 36711567 DOI: 10.1101/2023.01.04.522798  0.344
2022 Lu Y, Voros Z, Borjas G, Hendrickson C, Shearwin K, Dunlap D, Finzi L. RNA polymerase efficiently transcribes DNA-scaffolded, cooperative bacteriophage repressor complexes. Febs Letters. PMID 35819073 DOI: 10.1002/1873-3468.14447  0.491
2022 Xu W, Yan Y, Artsimovitch I, Dunlap D, Finzi L. Positive supercoiling favors transcription elongation through lac repressor-mediated DNA loops. Nucleic Acids Research. PMID 35188572 DOI: 10.1093/nar/gkac093  0.431
2021 Yan Y, Xu W, Kumar S, Zhang A, Leng F, Dunlap D, Finzi L. Negative DNA supercoiling makes protein-mediated looping deterministic and ergodic within the bacterial doubling time. Nucleic Acids Research. PMID 34723343 DOI: 10.1093/nar/gkab946  0.433
2021 Qian J, Xu W, Dunlap D, Finzi L. Single-molecule insights into torsion and roadblocks in bacterial transcript elongation. Transcription. 1-13. PMID 34719335 DOI: 10.1080/21541264.2021.1997315  0.437
2021 Salerno D, Marrano CA, Cassina V, Cristofalo M, Shao Q, Finzi L, Mantegazza F, Dunlap D. Nanomechanics of negatively supercoiled diaminopurine-substituted DNA. Nucleic Acids Research. PMID 34718727 DOI: 10.1093/nar/gkab982  0.619
2021 Xu W, Dunlap D, Finzi L. Energetics of twisted DNA topologies. Biophysical Journal. PMID 33974883 DOI: 10.1016/j.bpj.2021.05.002  0.491
2020 Qian J, Dunlap D, Finzi L. Basic mechanisms and kinetics of pause-interspersed transcript elongation. Nucleic Acids Research. PMID 33330935 DOI: 10.1093/nar/gkaa1182  0.302
2020 Yan Y, Xu W, Qian J, Artsimovitch I, Dunlap D, Finzi L. Transcriptional Obstacles Modify Repetitive Elongation Biophysical Journal. 118: 74a. DOI: 10.1016/J.Bpj.2019.11.579  0.325
2019 Yan Y, Finzi L, Dunlap DD. Supercoiling Makes Protein-Mediated Looping of DNA Tethers Deterministic Biophysical Journal. 116: 319a. DOI: 10.1016/J.Bpj.2018.11.1732  0.556
2019 Xu W, Yan Y, Dunlap DD, Finzi L. Loops Enhance Transcriptional Roadblocks Biophysical Journal. 116: 211a. DOI: 10.1016/J.Bpj.2018.11.1164  0.333
2018 Sarkar-Banerjee S, Goyal S, Gao N, Mack J, Thompson B, Dunlap D, Chattopadhyay K, Finzi L. Specifically bound lambda repressor dimers promote adjacent non-specific binding. Plos One. 13: e0194930. PMID 29608611 DOI: 10.1371/Journal.Pone.0194930  0.491
2018 Yan Y, Ding Y, Leng F, Dunlap D, Finzi L. Protein-mediated loops in supercoiled DNA create large topological domains. Nucleic Acids Research. PMID 29538766 DOI: 10.1093/Nar/Gky153  0.538
2018 Yan Y, Leng F, Finzi L, Dunlap D. Protein-mediated looping of DNA under tension requires supercoiling. Nucleic Acids Research. PMID 29365152 DOI: 10.1093/Nar/Gky021  0.587
2018 Kovari DT, Yan Y, Finzi L, Dunlap D. Tethered Particle Motion: An Easy Technique for Probing DNA Topology and Interactions with Transcription Factors. Methods in Molecular Biology (Clifton, N.J.). 1665: 317-340. PMID 28940077 DOI: 10.1007/978-1-4939-7271-5_17  0.486
2018 Kovari DT, Cristofalo M, Corti R, Salerno D, Cassina V, Lee Y, Malla G, Finzi L, Mantegazza F, Dunlap D. Experimentally Motivated Sequence-Dependent Models of Melting and Overstretching for Diaminopurine-Substituted DNA Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.524  0.469
2018 Vörös Z, Hendrickson CR, Dunlap D, Finzi L. Roadblocks by Protein-Mediated DNA Loops Biophysical Journal. 114: 249a. DOI: 10.1016/J.Bpj.2017.11.1385  0.562
2018 Finzi L. Protein-Mediated Loops in Supercoiled DNA Generate Large, Dynamic Topological Domains Biophysical Journal. 114: 12a-13a. DOI: 10.1016/J.Bpj.2017.11.112  0.481
2017 Vörös Z, Yan Y, Kovari DT, Finzi L, Dunlap D. Proteins mediating DNA loops effectively block transcription. Protein Science : a Publication of the Protein Society. PMID 28295806 DOI: 10.1002/Pro.3156  0.564
2017 Ucuncuoglu S, Schneider DA, Weeks ER, Dunlap D, Finzi L. Multiplexed, Tethered Particle Microscopy for Studies of DNA-Enzyme Dynamics. Methods in Enzymology. 582: 415-435. PMID 28062044 DOI: 10.1016/Bs.Mie.2016.08.008  0.593
2017 Kovari DT, Weeks E, Dunlap D, Finzi L. Tuning Up Tethered Particle Motion Biophysical Journal. 112: 70a. DOI: 10.1016/J.Bpj.2016.11.421  0.496
2017 Vörös Z, Dunlap D, Finzi L. Transcription Past Loop Forming Repressor Proteins Biophysical Journal. 112: 212a. DOI: 10.1016/J.Bpj.2016.11.1169  0.443
2016 Finzi L, Olson WK. The emerging role of DNA supercoiling as a dynamic player in genomic structure and function. Biophysical Reviews. 8: 1-3. PMID 28510213 DOI: 10.1007/S12551-016-0214-X  0.432
2016 Finzi L, Dunlap D. Supercoiling biases the formation of loops involved in gene regulation. Biophysical Reviews. 8: 65-74. PMID 28510212 DOI: 10.1007/S12551-016-0211-0  0.604
2016 Ucuncuoglu S, Engel KL, Purohit PK, Dunlap DD, Schneider DA, Finzi L. Direct Characterization of Transcription Elongation by RNA Polymerase I. Plos One. 11: e0159527. PMID 27455049 DOI: 10.1371/Journal.Pone.0159527  0.374
2016 Yan Y, Leng F, Dunlap DD, Finzi L. HU Protein and DNA Supercoiling Dramatically Enhance Lac-Repressor-Mediated DNA Looping Biophysical Journal. 110: 236a. DOI: 10.1016/J.Bpj.2015.11.1302  0.582
2016 Kovari DT, Cristofalo M, Dunlap D, Finzi L. The Overstretching Transition of Diaminopurine Substituted Triply Hydrogen-Bonded DNA Biophysical Journal. 110: 183a-184a. DOI: 10.1016/J.Bpj.2015.11.1023  0.568
2015 Fernández-Sierra M, Shao Q, Fountain C, Finzi L, Dunlap D. E. coli Gyrase Fails to Negatively Supercoil Diaminopurine-Substituted DNA. Journal of Molecular Biology. 427: 2305-18. PMID 25902201 DOI: 10.1016/J.Jmb.2015.04.006  0.674
2015 Yan Y, Kumar S, Finzi L, Dunlap DD. The Effect of HU Protein on Lac-Repressor-Mediated DNA Looping Biophysical Journal. 108: 74a-75a. DOI: 10.1016/J.Bpj.2014.11.441  0.583
2015 Ucuncuoglu S, Schneider DA, Dunlap DD, Finzi L. A Single Molecule Perspective of Elongation by RNA Polymerase I Biophysical Journal. 108: 508a. DOI: 10.1016/J.Bpj.2014.11.2779  0.44
2014 Ding Y, Manzo C, Fulcrand G, Leng F, Dunlap D, Finzi L. DNA supercoiling: a regulatory signal for the λ repressor. Proceedings of the National Academy of Sciences of the United States of America. 111: 15402-7. PMID 25319264 DOI: 10.1073/Pnas.1320644111  0.611
2014 Kumar S, Manzo C, Zurla C, Ucuncuoglu S, Finzi L, Dunlap D. Enhanced tethered-particle motion analysis reveals viscous effects Biophysical Journal. 106: 399-409. PMID 24461015 DOI: 10.1016/J.Bpj.2013.11.4501  0.386
2014 Ding Y, Manzo C, Fulcrand G, Leng F, Dunlap D, Finzi L. DNA supercoiling: A regulatory signal for the λ repressor Proceedings of the National Academy of Sciences of the United States of America. 111: 15402-15407. DOI: 10.1073/pnas.1320644111  0.434
2014 Ucuncuoglu S, Schneider DA, Dunlap DD, Finzi L. Single Molecule Investigation of RNA Polymerase I using Multiplexed Tethered Particle Motion Biophysical Journal. 106: 489a. DOI: 10.1016/J.Bpj.2013.11.4482  0.469
2014 Shao Q, Fernandez M, Owino S, Lee Y, Finzi L, Dunlap D. Diaminopurine-Substitution Modify DNA Elasticity and Favors L-Helices Biophysical Journal. 106: 66a. DOI: 10.1016/J.Bpj.2013.11.443  0.498
2014 Finzi L. Genetic Switches and Transcriptional Regulation: Insights from Single Molecules Biophysical Journal. 106: 626a. DOI: 10.1016/J.Bpj.2013.11.3465  0.513
2014 Ding Y, Jurchenko C, Dunlap D, Finzi L, Salaita K. A Combined Single Molecule FRET/Magnetic Tweezers Instrument to Calibrate Molecular Tension - Based Fluorescence Probes Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.1152  0.304
2013 Mendes MA, Guerra RF, Berns MC, Manzo C, Masiero S, Finzi L, Kater MM, Colombo L. MADS domain transcription factors mediate short-range DNA looping that is essential for target gene expression in Arabidopsis Plant Cell. 25: 2560-2572. PMID 23847151 DOI: 10.1105/Tpc.112.108688  0.38
2013 Gao N, Shearwin K, Mack J, Finzi L, Dunlap D. Purification of bacteriophage lambda repressor Protein Expression and Purification. 91: 30-36. PMID 23831434 DOI: 10.1016/J.Pep.2013.06.013  0.394
2013 Wang H, Dodd IB, Dunlap DD, Shearwin KE, Finzi L. Single molecule analysis of DNA wrapping and looping by a circular 14mer wheel of the bacteriophage 186 CI repressor Nucleic Acids Research. 41: 5746-5756. PMID 23620280 DOI: 10.1093/Nar/Gkt298  0.689
2013 Fernández-Sierra M, Fountain CH, Finzi L, Dunlap DD. Single-Molecule Assessment of DNA Supercoiling and Relaxation by S. Typhimurium and E. Coli DNA Gyrases Biophysical Journal. 104: 165a. DOI: 10.1016/J.Bpj.2012.11.928  0.54
2013 Ucuncuoglu S, Schneider DA, Finzi L. Single Molecule Characterization of RNA Polymerase I: Force Free Kinetic Measurements Biophysical Journal. 104: 585a. DOI: 10.1016/J.Bpj.2012.11.3254  0.385
2013 Ding Y, Manzo C, Dunlap D, Finzi L. DNA supercoiling affects Stability of Genetic Switch Biophysical Journal. 104: 261a-262a. DOI: 10.1016/J.Bpj.2012.11.1469  0.592
2012 Shao Q, Goyal S, Finzi L, Dunlap D. Physiological levels of salt and polyamines favor writhe and limit twist in DNA. Macromolecules. 45: 3188-3196. PMID 23526178 DOI: 10.1021/Ma300211T  0.678
2012 Manzo C, Zurla C, Dunlap DD, Finzi L. The effect of nonspecific binding of lambda repressor on DNA looping dynamics Biophysical Journal. 103: 1753-1761. PMID 23083719 DOI: 10.1016/J.Bpj.2012.09.006  0.488
2012 Goyal S, Fountain C, Dunlap D, Family F, Finzi L. Stretching DNA to quantify nonspecific protein binding. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 86: 011905. PMID 23005450 DOI: 10.1103/Physreve.86.011905  0.567
2012 Goyal S, Fountain C, Dunlap D, Family F, Finzi L. Stretching DNA to quantify nonspecific protein binding Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. 86. DOI: 10.1103/PhysRevE.86.011905  0.438
2012 Shao Q, Goyal S, Finzi L, Dunlap D. Physiological levels of salt and polyamines favor writhe and limit twist in DNA Macromolecules. 45: 3188-3196. DOI: 10.1021/ma300211t  0.443
2012 Ding Y, Manzo C, Dunlap D, Finzi L. The Effects of Tension and Supercoiling on Protein-Mediated DNA Looping Biophysical Journal. 102: 73a. DOI: 10.1016/J.Bpj.2011.11.426  0.593
2012 Wang H, Dodd IB, Keith S, Dunlap D, Finzi L. Automated DNA Tracing on AFM Images Helps the Study of 186 Repressor-DNA Interactions Biophysical Journal. 102: 601a-602a. DOI: 10.1016/J.Bpj.2011.11.3276  0.69
2012 Kumar S, Zurla C, Goyal S, Finzi L, Dunlap D. Effects of Viscosity on Tethered Particle Motion (TPM) Experiments Biophysical Journal. 102: 3-3. DOI: 10.1016/J.Bpj.2011.11.2099  0.571
2012 Shao Q, Finzi L, Dunlap D. Triple Hydrogen Bonds in DNA Modify the Transition from Right- to Left- Handed Forms Biophysical Journal. 102: 274a-275a. DOI: 10.1016/J.Bpj.2011.11.1513  0.653
2011 Dunlap D, Zurla C, Manzo C, Finzi L. Probing DNA topology using tethered particle motion Methods in Molecular Biology. 783: 295-313. PMID 21909895 DOI: 10.1007/978-1-61779-282-3_16  0.573
2011 Lewis D, Le P, Zurla C, Finzi L, Adhya S. Multilevel autoregulation of λ repressor protein CI by DNA looping in vitro Proceedings of the National Academy of Sciences of the United States of America. 108: 14807-14812. PMID 21873207 DOI: 10.1073/Pnas.1111221108  0.572
2011 Shao Q, Goyal S, Finzi L, Dunlap DD. Probing DNA Stiffness with Magnetic Tweezers Biophysical Journal. 100: 75a. DOI: 10.1016/J.Bpj.2010.12.616  0.678
2011 Finzi L, Manzo C, Zurla C, Adhya S, Dunlap DD. Kinetic Studies of Lambda Repressor-Mediated DNA Looping Suggest Physiological Role for Non-Specific Binding Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.587  0.52
2011 Goyal S, Fountain C, Dunlap D, Family F, Finzi L. Stretching DNA to Quantify Non-Specific Binding by the Lambda Repressor (ci) Biophysical Journal. 100: 70a. DOI: 10.1016/J.Bpj.2010.12.585  0.522
2011 Wang H, Dodd I, Shearwin K, Dunlap D, Finzi L. The 186 Bacteriophage Repressor as a Model System to Study Nucleosome Repositioning by Single Molecule Microscopy Biophysical Journal. 100: 230a. DOI: 10.1016/J.Bpj.2010.12.1471  0.667
2011 Shao Q, Dunlap D, Finzi L. Dynamics of DNA Supercoil Relaxation by Type II Topoisomerases Biophysical Journal. 100: 192a. DOI: 10.1016/J.Bpj.2010.12.1264  0.644
2010 Liebesny P, Goyal S, Dunlap D, Family F, Finzi L. Determination of the number of proteins bound non-specifically to DNA Journal of Physics Condensed Matter. 22. PMID 21386587 DOI: 10.1088/0953-8984/22/41/414104  0.591
2010 Manzo C, Finzi L. Quantitative Analysis of DNA-Looping Kinetics from Tethered Particle Motion Experiments Methods in Enzymology. 475: 199-220. PMID 20627159 DOI: 10.1016/S0076-6879(10)75009-6  0.475
2010 Finzi L, Dunlap DD. Single-molecule approaches to probe the structure, kinetics, and thermodynamics of nucleoprotein complexes that regulate transcription Journal of Biological Chemistry. 285: 18973-18978. PMID 20382734 DOI: 10.1074/Jbc.R109.062612  0.562
2010 Finzi L, Manzo C, Zurla C, Dunlap DD. Complex Kinetics of the λ Repressor-Mediated DNA Loop Biophysical Journal. 98: 75a. DOI: 10.1016/J.Bpj.2009.12.423  0.558
2010 Wang H, Dodd IB, Shearwin K, Dunlap D, Finzi L. Coliphage 186 Genetic Switch: A Single Molecule Study Biophysical Journal. 98: 71a. DOI: 10.1016/J.Bpj.2009.12.403  0.72
2010 Shao Q, Finzi L, Dunlap D. Dynamic Investigation of DNA Bending and Wrapping By Type II Topoisomerases Biophysical Journal. 98: 70a-71a. DOI: 10.1016/J.Bpj.2009.12.401  0.643
2010 Wang H, Finzi L, Lewis DA, Dunlap DD. AFM Studies of DNA Loops Secured by Lambda Repressor Proteins Biophysical Journal. 98: 662a. DOI: 10.1016/J.Bpj.2009.12.3632  0.652
2009 Wang H, Finzi L, Lewis DEA, Dunlap D. AFM studies of λ repressor oligomers securing DNA loops Current Pharmaceutical Biotechnology. 10: 494-501. PMID 19689317 DOI: 10.2174/138920109788922155  0.611
2009 Zurla C, Manzo C, Dunlap D, Lewis DEA, Adhya S, Finzi L. Direct demonstration and quantification of long-range DNA looping by the λ bacteriophage repressor Nucleic Acids Research. 37: 2789-2795. PMID 19276206 DOI: 10.1093/Nar/Gkp134  0.513
2009 Finzi L, Zurla C, Manzo C, Dunlap D. Elucidation of the Mechanism of an Epigenetic Switch by Single-molecule Assays Biophysical Journal. 96: 343a. DOI: 10.1016/J.Bpj.2008.12.1724  0.542
2008 Lia G, Indrieri M, Owen-Hughes T, Finzi L, Podesta A, Milani P, Dunlap D. ATP-dependent looping of DNA by ISWI Journal of Biophotonics. 1: 280-286. PMID 19343651 DOI: 10.1002/Jbio.200810027  0.518
2008 Lia G, Semsey S, Lewis DEA, Adhya S, Bensimon D, Dunlap D, Finzi L. The antiparallel loops in gal DNA Nucleic Acids Research. 36: 4204-4210. PMID 18573800 DOI: 10.1093/Nar/Gkn389  0.587
2007 Zurla C, Samuely T, Bertoni G, Valle F, Dietler G, Finzi L, Dunlap DD. Integration host factor alters LacI-induced DNA looping Biophysical Chemistry. 128: 245-252. PMID 17543441 DOI: 10.1016/J.Bpc.2007.04.012  0.599
2007 Guerra RF, Imperadori L, Mantovani R, Dunlap DD, Finzi L. DNA compaction by the nuclear factor-Y Biophysical Journal. 93: 176-182. PMID 17434933 DOI: 10.1529/Biophysj.106.099929  0.444
2007 Beausang JF, Zurla C, Manzo C, Dunlap D, Finzi L, Nelson PC. DNA looping kinetics analyzed using diffusive hidden Markov model. Biophysical Journal. 92: L64-6. PMID 17277177 DOI: 10.1529/Biophysj.107.104828  0.433
2006 Nelson PC, Zurla C, Brogioli D, Beausang JF, Finzi L, Dunlap D. Tethered particle motion as a diagnostic of DNA tether length. The Journal of Physical Chemistry. B. 110: 17260-7. PMID 16928025 DOI: 10.1021/Jp0630673  0.485
2006 Zurla C, Franzini A, Galli G, Dunlap DD, Lewis DEA, Adhya S, Finzi L. Novel tethered particle motion analysis of CI protein-mediated DNA looping in the regulation of bacteriophage lambda Journal of Physics Condensed Matter. 18: S225-S234. DOI: 10.1088/0953-8984/18/14/S07  0.506
2005 Podestà A, Indrieri M, Brogioli D, Manning GS, Milani P, Guerra R, Finzi L, Dunlap D. Positively charged surfaces increase the flexibility of DNA Biophysical Journal. 89: 2558-2563. PMID 16040760 DOI: 10.1529/Biophysj.105.064667  0.564
2005 Kooiker M, Airoldi CA, Losa A, Manzotti PS, Finzi L, Kater MM, Colombo L. Basic Pentacysteine1, a GA binding protein that induces conformational changes in the regulatory region of the homeotic Arabidopsis gene Seedstick Plant Cell. 17: 722-729. PMID 15722463 DOI: 10.1105/Tpc.104.030130  0.324
2004 Podestà A, Imperadori L, Colnaghi W, Finzi L, Milani P, Dunlap D. Atomic force microscopy study of DNA deposited on poly L-ornithine-coated mica Journal of Microscopy. 215: 236-240. PMID 15312188 DOI: 10.1111/J.0022-2720.2004.01372.X  0.538
2003 Finzi L, Dunlap D. Single-Molecule Studies of DNA Architectural Changes Induced by Regulatory Proteins Methods in Enzymology. 370: 369-378. PMID 14712660 DOI: 10.1016/S0076-6879(03)70032-9  0.527
2003 Lia G, Bensimon D, Croquette V, Allemand JF, Dunlap D, Lewis DEA, Adhya S, Finzi L. Supercoiling and denaturation in Gal repressor/heat unstable nucleoid protein (HU)-mediated DNA looping Proceedings of the National Academy of Sciences of the United States of America. 100: 11373-11377. PMID 14500788 DOI: 10.1073/Pnas.2034851100  0.638
1999 Boggia R, Fanciullo M, Finzi L, Incani O, Mosti L. DNA-psoralens molecular recognition using molecular dynamics Farmaco. 54: 202-212. DOI: 10.1016/S0014-827X(99)00012-9  0.345
1995 Finzi L, Gelles J. Measurement of lactose repressor-mediated loop formation and breakdown in single DNA molecules. Science (New York, N.Y.). 267: 378-80. PMID 7824935 DOI: 10.1126/Science.7824935  0.709
1995 Gelles J, Yin H, Finzi L, Wong OK, Landick R. Single-molecule kinetic studies on DNA transcription and transcriptional regulation. Biophysical Journal. 68: 73S. PMID 7787108  0.765
1992 Smith SB, Finzi L, Bustamante C. Direct mechanical measurements of the elasticity of single DNA molecules by using magnetic beads Science. 258: 1122-1126. PMID 1439819 DOI: 10.1126/Science.1439819  0.52
1991 Bustamante C, Finzi L, Sebring PE, Smith SB. Manipulation of single-DNA molecules and measurements of their elastic properties under an optical microscope Proceedings of Spie - the International Society For Optical Engineering. 1435: 179-187.  0.349
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