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Xiao Tian - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
Aging, neurobiology, epigenetics
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2025 Miller KN, Li B, Pierce-Hoffman HR, Patel S, Lei X, Rajesh A, Teneche MG, Havas AP, Gandhi A, Macip CC, Lyu J, Victorelli SG, Woo SH, Lagnado AB, LaPorta MA, ... ... Tian X, et al. p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells. Nature Communications. 16: 2229. PMID 40044657 DOI: 10.1038/s41467-025-57229-3  0.673
2024 Firsanov D, Zacher M, Tian X, Sformo TL, Zhao Y, Tombline G, Lu JY, Zheng Z, Perelli L, Gurreri E, Zhang L, Guo J, Korotkov A, Volobaev V, Biashad SA, et al. DNA repair and anti-cancer mechanisms in the long-lived bowhead whale. Biorxiv : the Preprint Server For Biology. PMID 39574710 DOI: 10.1101/2023.05.07.539748  0.705
2024 Kane AE, Chellappa K, Schultz MB, Arnold M, Li J, Amorim J, Diener C, Zhu D, Mitchell SJ, Griffin P, Tian X, Petty C, Conway R, Walsh K, Shelerud L, et al. Long-term NMN treatment increases lifespan and healthspan in mice in a sex dependent manner. Biorxiv : the Preprint Server For Biology. PMID 38979132 DOI: 10.1101/2024.06.21.599604  0.405
2024 Yang JH, Hayano M, Griffin PT, Amorim JA, Bonkowski MS, Apostolides JK, Salfati EL, Blanchette M, Munding EM, Bhakta M, Chew YC, Guo W, Yang X, Maybury-Lewis S, Tian X, et al. Loss of epigenetic information as a cause of mammalian aging. Cell. 187: 1312-1313. PMID 38428398 DOI: 10.1016/j.cell.2024.01.049  0.56
2024 Griffin PT, Kane AE, Trapp A, Li J, Arnold M, Poganik JR, Conway RJ, McNamara MS, Meer MV, Hoffman N, Amorim JA, Tian X, MacArthur MR, Mitchell SJ, Mueller AL, et al. TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction. Nature Aging. PMID 38200273 DOI: 10.1038/s43587-023-00555-2  0.412
2023 Lu YR, Tian X, Sinclair DA. The Information Theory of Aging. Nature Aging. 3: 1486-1499. PMID 38102202 DOI: 10.1038/s43587-023-00527-6  0.434
2023 Tian X, Sinclair DA. Restricting mealtime ameliorates neurodegeneration. Cell Metabolism. 35: 1673-1674. PMID 37793341 DOI: 10.1016/j.cmet.2023.09.006  0.32
2023 Zhang Z, Tian X, Lu JY, Boit K, Ablaeva J, Zakusilo FT, Emmrich S, Firsanov D, Rydkina E, Biashad SA, Lu Q, Tyshkovskiy A, Gladyshev VN, Horvath S, Seluanov A, et al. Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice. Nature. PMID 37612507 DOI: 10.1038/s41586-023-06463-0  0.675
2023 Yang JH, Petty CA, Dixon-McDougall T, Lopez MV, Tyshkovskiy A, Maybury-Lewis S, Tian X, Ibrahim N, Chen Z, Griffin PT, Arnold M, Li J, Martinez OA, Behn A, Rogers-Hammond R, et al. Chemically induced reprogramming to reverse cellular aging. Aging. 15. PMID 37437248 DOI: 10.18632/aging.204896  0.479
2023 Yang JH, Hayano M, Griffin PT, Amorim JA, Bonkowski MS, Apostolides JK, Salfati EL, Blanchette M, Munding EM, Bhakta M, Chew YC, Guo W, Yang X, Maybury-Lewis S, Tian X, et al. Loss of epigenetic information as a cause of mammalian aging. Cell. PMID 36638792 DOI: 10.1016/j.cell.2022.12.027  0.613
2021 Zhang L, Dong X, Tian X, Lee M, Ablaeva J, Firsanov D, Lee SG, Maslov AY, Gladyshev VN, Seluanov A, Gorbunova V, Vijg J. Maintenance of genome sequence integrity in long- and short-lived rodent species. Science Advances. 7: eabj3284. PMID 34705500 DOI: 10.1126/sciadv.abj3284  0.607
2021 Buffenstein R, Amoroso V, Andziak B, Avdieiev S, Azpurua J, Barker AJ, Bennett NC, Brieño-Enríquez MA, Bronner GN, Coen C, Delaney MA, Dengler-Crish CM, Edrey YH, Faulkes CG, Frankel D, ... ... Tian X, et al. The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole-rat biology. Biological Reviews of the Cambridge Philosophical Society. PMID 34476892 DOI: 10.1111/brv.12791  0.724
2020 Lu Y, Brommer B, Tian X, Krishnan A, Meer M, Wang C, Vera DL, Zeng Q, Yu D, Bonkowski MS, Yang JH, Zhou S, Hoffmann EM, Karg MM, Schultz MB, et al. Reprogramming to recover youthful epigenetic information and restore vision. Nature. 588: 124-129. PMID 33268865 DOI: 10.1038/s41586-020-2975-4  0.444
2020 Zhou X, Dou Q, Fan G, Zhang Q, Sanderford M, Kaya A, Johnson J, Karlsson EK, Tian X, Mikhalchenko A, Kumar S, Seluanov A, Zhang ZD, Gorbunova V, Liu X, et al. Beaver and Naked Mole Rat Genomes Reveal Common Paths to Longevity. Cell Reports. 32: 107949. PMID 32726638 DOI: 10.1016/J.Celrep.2020.107949  0.653
2020 Zhao J, Tian X, Zhu Y, Zhang Z, Rydkina E, Yuan Y, Zhang H, Roy B, Cornwell A, Nevo E, Shang X, Huang R, Kristiansen K, Seluanov A, Fang X, et al. Reply to: Transformation of naked mole-rat cells. Nature. 583: E8-E13. PMID 32612220 DOI: 10.1038/S41586-020-2411-9  0.637
2019 Chen Y, Zhang H, Xu Z, Tang H, Geng A, Cai B, Su T, Shi J, Jiang C, Tian X, Seluanov A, Huang J, Wan X, Jiang Y, Gorbunova V, et al. A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites. Nucleic Acids Research. PMID 31291457 DOI: 10.1093/Nar/Gkz592  0.73
2019 Katagi H, Louis N, Unruh D, Sasaki T, He X, Zhang A, Ma Q, Piunti A, Shimazu Y, Lamano JB, Carcaboso AM, Tian X, Seluanov A, Gorbunova V, Laurie KL, et al. Radiosensitization by Histone H3 Demethylase Inhibition in Diffuse Intrinsic Pontine Glioma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31227500 DOI: 10.1158/1078-0432.Ccr-18-3890  0.599
2019 Tian X, Firsanov D, Zhang Z, Cheng Y, Luo L, Tombline G, Tan R, Simon M, Henderson S, Steffan J, Goldfarb A, Tam J, Zheng K, Cornwell A, Johnson A, et al. SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. Cell. 177: 622-638.e22. PMID 31002797 DOI: 10.1016/J.Cell.2019.03.043  0.745
2018 Zhao Y, Tyshkovskiy A, Muñoz-Espín D, Tian X, Serrano M, de Magalhaes JP, Nevo E, Gladyshev VN, Seluanov A, Gorbunova V. Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence. Proceedings of the National Academy of Sciences of the United States of America. PMID 29432174 DOI: 10.1073/Pnas.1721160115  0.696
2018 Tian X, Doerig K, Park R, Can Ran Qin A, Hwang C, Neary A, Gilbert M, Seluanov A, Gorbunova V. Evolution of telomere maintenance and tumour suppressor mechanisms across mammals. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29335367 DOI: 10.1098/Rstb.2016.0443  0.633
2017 Tan L, Ke Z, Tombline G, Macoretta N, Hayes K, Tian X, Lv R, Ablaeva J, Gilbert M, Bhanu NV, Yuan ZF, Garcia BA, Shi YG, Shi Y, Seluanov A, et al. Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming. Stem Cell Reports. PMID 29107597 DOI: 10.1016/J.Stemcr.2017.10.001  0.658
2017 Tian X, Seluanov A, Gorbunova V. Molecular Mechanisms Determining Lifespan in Short- and Long-Lived Species. Trends in Endocrinology and Metabolism: Tem. PMID 28888702 DOI: 10.1016/J.Tem.2017.07.004  0.646
2017 Tian X, Seluanov A, Gorbunova V. Beyond Making Ends Meet: DNA-PK, Metabolism, and Aging. Cell Metabolism. 25: 991-992. PMID 28467943 DOI: 10.1016/J.Cmet.2017.04.022  0.648
2016 Patrick A, Seluanov M, Hwang C, Tam J, Khan T, Morgenstern A, Wiener L, Vazquez JM, Zafar H, Wen R, Muratkalyeva M, Doerig K, Zagorulya M, Cole L, Catalano S, ... ... Tian X, et al. Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan. Aging. PMID 27163160  0.637
2015 Tian X, Azpurua J, Ke Z, Augereau A, Zhang ZD, Vijg J, Gladyshev VN, Gorbunova V, Seluanov A. INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform. Proceedings of the National Academy of Sciences of the United States of America. 112: 1053-8. PMID 25550505 DOI: 10.1073/Pnas.1418203112  0.758
2014 Vaidya A, Mao Z, Tian X, Spencer B, Seluanov A, Gorbunova V. Knock-in reporter mice demonstrate that DNA repair by non-homologous end joining declines with age. Plos Genetics. 10: e1004511. PMID 25033455 DOI: 10.1371/Journal.Pgen.1004511  0.744
2014 Cao Y, Xu Y, Zhang L, Li Z, Jiang Y, Tian X, Seluanov A, Gorbunova V, Mao Z. Utilization of Rad51C promoter for transcriptional targeting of cancer cells. Oncotarget. 5: 1805-11. PMID 24742710 DOI: 10.18632/Oncotarget.1792  0.728
2013 Tian X, Azpurua J, Hine C, Vaidya A, Myakishev-Rempel M, Ablaeva J, Mao Z, Nevo E, Gorbunova V, Seluanov A. High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat. Nature. 499: 346-9. PMID 23783513 DOI: 10.1038/Nature12234  0.729
2012 Gorbunova V, Hine C, Tian X, Ablaeva J, Gudkov AV, Nevo E, Seluanov A. Cancer resistance in the blind mole rat is mediated by concerted necrotic cell death mechanism. Proceedings of the National Academy of Sciences of the United States of America. 109: 19392-6. PMID 23129611 DOI: 10.1073/Pnas.1217211109  0.76
2012 Mao Z, Tian X, Van Meter M, Ke Z, Gorbunova V, Seluanov A. Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence. Proceedings of the National Academy of Sciences of the United States of America. 109: 11800-5. PMID 22753495 DOI: 10.1073/Pnas.1200583109  0.76
2011 Mao Z, Hine C, Tian X, Van Meter M, Au M, Vaidya A, Seluanov A, Gorbunova V. SIRT6 promotes DNA repair under stress by activating PARP1. Science (New York, N.Y.). 332: 1443-6. PMID 21680843 DOI: 10.1126/Science.1202723  0.752
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