Year |
Citation |
Score |
2023 |
Zhang L, Jiang C, Zhong Y, Sun K, Jing H, Song J, Xie J, Zhou Y, Tian M, Zhang C, Sun X, Wang S, Cheng X, Zhang Y, Wei W, ... ... Shu HB, et al. STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2. Nature Cell Biology. PMID 37443289 DOI: 10.1038/s41556-023-01185-x |
0.3 |
|
2023 |
Guo Y, Zhang XN, Su S, Ruan ZL, Hu MM, Shu HB. β-adrenoreceptor-triggered PKA activation negatively regulates the innate antiviral response. Cellular & Molecular Immunology. PMID 36600052 DOI: 10.1038/s41423-022-00967-x |
0.584 |
|
2022 |
Yang YL, Cao LB, He WR, Zhong L, Guo Y, Yang Q, Shu HB, Hu MM. Endocytosis triggers V-ATPase-SYK-mediated priming of cGAS activation and innate immune response. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207280119. PMID 36252040 DOI: 10.1073/pnas.2207280119 |
0.441 |
|
2022 |
Zhong B, Shu HB. MITA/STING-mediated antiviral immunity and autoimmunity: the evolution, mechanism, and intervention. Current Opinion in Immunology. 78: 102248. PMID 36193584 DOI: 10.1016/j.coi.2022.102248 |
0.341 |
|
2022 |
Su S, Hua D, Li JP, Zhang XN, Bai L, Cao LB, Guo Y, Zhang M, Dong JZ, Liang XW, Lan K, Hu MM, Shu HB. Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone. Signal Transduction and Targeted Therapy. 7: 137. PMID 35468896 DOI: 10.1038/s41392-022-00981-5 |
0.525 |
|
2021 |
Li C, Feng L, Luo WW, Lei CQ, Li M, Shu HB. The RNA-binding protein LUC7L2 mediates MITA/STING intron retention to negatively regulate innate antiviral response. Cell Discovery. 7: 46. PMID 34155193 DOI: 10.1038/s41421-021-00277-y |
0.541 |
|
2021 |
Guo W, Wei J, Zhong X, Zang R, Lian H, Hu MM, Li S, Shu HB, Yang Q. Correction to: SNX8 modulates the innate immune response to RNA viruses by regulating the aggregation of VISA. Cellular & Molecular Immunology. PMID 33958747 DOI: 10.1038/s41423-021-00682-z |
0.438 |
|
2021 |
He WR, Cao LB, Yang YL, Hua D, Hu MM, Shu HB. VRK2 is involved in the innate antiviral response by promoting mitostress-induced mtDNA release. Cellular & Molecular Immunology. PMID 33785841 DOI: 10.1038/s41423-021-00673-0 |
0.41 |
|
2021 |
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Shu HB, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280 |
0.469 |
|
2020 |
Sun X, Liu T, Zhao J, Xia H, Xie J, Guo Y, Zhong L, Li M, Yang Q, Peng C, Rouvet I, Belot A, Shu HB, Feng P, Zhang J. DNA-PK deficiency potentiates cGAS-mediated antiviral innate immunity. Nature Communications. 11: 6182. PMID 33273464 DOI: 10.1038/s41467-020-19941-0 |
0.311 |
|
2020 |
Song ZM, Lin H, Yi XM, Guo W, Hu MM, Shu HB. KAT5 acetylates cGAS to promote innate immune response to DNA virus. Proceedings of the National Academy of Sciences of the United States of America. PMID 32817552 DOI: 10.1073/pnas.1922330117 |
0.39 |
|
2020 |
Li M, Shu HB. Dephosphorylation of cGAS by PPP6C impairs its substrate binding activity and innate antiviral response. Protein & Cell. PMID 32474700 DOI: 10.1007/s13238-020-00729-3 |
0.424 |
|
2020 |
Liao CY, Lei CQ, Shu HB. PCBP1 modulates the innate immune response by facilitating the binding of cGAS to DNA. Cellular & Molecular Immunology. PMID 32415261 DOI: 10.1038/S41423-020-0462-3 |
0.33 |
|
2020 |
Zhong X, Feng L, Zang R, Lei CQ, Yang Q, Shu HB. ZFYVE1 negatively regulates MDA5- but not RIG-I-mediated innate antiviral response. Plos Pathogens. 16: e1008457. PMID 32251420 DOI: 10.1371/Journal.Ppat.1008457 |
0.492 |
|
2020 |
Gao P, Hu MM, Shu HB. CSK promotes innate immune response to DNA virus by phosphorylating MITA. Biochemical and Biophysical Research Communications. PMID 32201077 DOI: 10.1016/j.bbrc.2020.03.069 |
0.461 |
|
2020 |
Zang R, Lian H, Zhong X, Yang Q, Shu HB. ZCCHC3 modulates TLR3-mediated signaling by promoting recruitment of TRIF to TLR3. Journal of Molecular Cell Biology. PMID 32133501 DOI: 10.1093/jmcb/mjaa004 |
0.378 |
|
2020 |
Yang Q, Shu HB. Deciphering the pathways to antiviral innate immunity and inflammation. Advances in Immunology. 145: 1-36. PMID 32081195 DOI: 10.1016/bs.ai.2019.11.001 |
0.491 |
|
2020 |
Chuan G, Chen L, Tang SB, Long QY, He JL, Zhang NA, Shu HB, Chen ZX, Wu M, Li LY. The epigenetic landscapes of histone modifications on HSV-1 genome in human THP-1 cells. Antiviral Research. 104730. PMID 32014498 DOI: 10.1016/j.antiviral.2020.104730 |
0.315 |
|
2019 |
Xia T, Yi XM, Wu X, Shang J, Shu HB. PTPN1/2-mediated dephosphorylation of MITA/STING promotes its 20S proteasomal degradation and attenuates innate antiviral response. Proceedings of the National Academy of Sciences of the United States of America. PMID 31527250 DOI: 10.1073/pnas.1906431116 |
0.527 |
|
2019 |
Guo W, Wei J, Zhong X, Zang R, Lian H, Hu MM, Li S, Shu HB, Yang Q. SNX8 modulates the innate immune response to RNA viruses by regulating the aggregation of VISA. Cellular & Molecular Immunology. PMID 31511639 DOI: 10.1038/s41423-019-0285-2 |
0.559 |
|
2019 |
Wu X, Lei C, Xia T, Zhong X, Yang Q, Shu HB. Regulation of TRIF-mediated innate immune response by K27-linked polyubiquitination and deubiquitination. Nature Communications. 10: 4115. PMID 31511519 DOI: 10.1038/S41467-019-12145-1 |
0.376 |
|
2019 |
Lin H, Li S, Shu HB. The Membrane-Associated MARCH E3 Ligase Family: Emerging Roles in Immune Regulation. Frontiers in Immunology. 10: 1751. PMID 31404274 DOI: 10.3389/fimmu.2019.01751 |
0.353 |
|
2019 |
Zhong X, Feng L, Xu WH, Wu X, Ding YD, Zhou Y, Lei CQ, Shu HB. The zinc-finger protein ZFYVE1 modulates TLR3-mediated signaling by facilitating TLR3 ligand binding. Cellular & Molecular Immunology. PMID 31388100 DOI: 10.1038/S41423-019-0265-6 |
0.307 |
|
2019 |
Li D, Fu S, Wu Z, Yang W, Ru Y, Shu H, Liu X, Zheng H. DDX56 inhibits type I interferon by disrupting assembly of IRF3-IPO5 to inhibit IRF3 nucleus import. Journal of Cell Science. 133. PMID 31340999 DOI: 10.1242/jcs.230409 |
0.47 |
|
2019 |
Hu MM, He WR, Gao P, Yang Q, He K, Cao LB, Li S, Feng YQ, Shu HB. Virus-induced accumulation of intracellular bile acids activates the TGR5-β-arrestin-SRC axis to enable innate antiviral immunity. Cell Research. PMID 30651583 DOI: 10.1038/s41422-018-0136-1 |
0.523 |
|
2018 |
Sun MS, Zhang J, Jiang LQ, Pan YX, Tan JY, Yu F, Guo L, Yin L, Shen C, Shu HB, Liu Y. TMED2 Potentiates Cellular IFN Responses to DNA Viruses by Reinforcing MITA Dimerization and Facilitating Its Trafficking. Cell Reports. 25: 3086-3098.e3. PMID 30540941 DOI: 10.1016/j.celrep.2018.11.048 |
0.452 |
|
2018 |
Xie T, Chen T, Li C, Wang W, Cao L, Rao H, Yang Q, Shu HB, Xu LG. RACK1 attenuates RLR antiviral signaling by targeting VISA-TRAF complexes. Biochemical and Biophysical Research Communications. PMID 30527812 DOI: 10.1016/j.bbrc.2018.11.203 |
0.507 |
|
2018 |
Ling T, Li SN, Weng GX, Wang W, Li C, Cao L, Rao H, Shu HB, Xu LG. TARBP2 negatively regulates IFN-β production and innate antiviral response by targeting MAVS. Molecular Immunology. 104: 1-10. PMID 30390472 DOI: 10.1016/j.molimm.2018.10.017 |
0.523 |
|
2018 |
Wei J, Lian H, Guo W, Chen YD, Zhang XN, Zang R, Zhong L, Yang Q, Hu MM, Luo WW, Shu HB, Li S. SNX8 modulates innate immune response to DNA virus by mediating trafficking and activation of MITA. Plos Pathogens. 14: e1007336. PMID 30321235 DOI: 10.1371/journal.ppat.1007336 |
0.423 |
|
2018 |
Lian H, Zang R, Wei J, Ye W, Hu MM, Chen YD, Zhang XN, Guo Y, Lei CQ, Yang Q, Luo WW, Li S, Shu HB. The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors. Immunity. PMID 30193849 DOI: 10.1016/J.Immuni.2018.08.014 |
0.507 |
|
2018 |
Lian H, Wei J, Zang R, Ye W, Yang Q, Zhang XN, Chen YD, Fu YZ, Hu MM, Lei CQ, Luo WW, Li S, Shu HB. ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response. Nature Communications. 9: 3349. PMID 30135424 DOI: 10.1038/S41467-018-05559-W |
0.459 |
|
2018 |
Hu MM, Shu HB. Cytoplasmic Mechanisms of Recognition and Defense of Microbial Nucleic Acids. Annual Review of Cell and Developmental Biology. PMID 30095291 DOI: 10.1146/annurev-cellbio-100617-062903 |
0.303 |
|
2018 |
Wang J, Zeng Y, Xu S, Yang J, Wang W, Zhong B, Ge J, Yin L, Bu Z, Shu HB, Chen H, Lei CQ, Zhu Q. A Naturally Occurring Deletion in the Effector Domain of H5N1 Swine Influenza Virus Nonstructural Protein 1 Regulates Viral Fitness and Host Innate Immunity. Journal of Virology. PMID 29563291 DOI: 10.1128/Jvi.00149-18 |
0.459 |
|
2018 |
Luo WW, Shu HB. Delicate regulation of the cGAS-MITA-mediated innate immune response. Cellular & Molecular Immunology. PMID 29456253 DOI: 10.1038/cmi.2016.51 |
0.345 |
|
2018 |
Liu Y, Zhou Q, Zhong L, Lin H, Hu MM, Zhou Y, Shu HB, Li S. ZDHHC11 modulates innate immune response to DNA virus by mediating MITA-IRF3 association. Cellular & Molecular Immunology. PMID 29429998 DOI: 10.1038/cmi.2017.146 |
0.484 |
|
2017 |
Shang J, Xia T, Han QQ, Zhao X, Hu MM, Shu HB, Guo L. Quantitative Proteomics Identified TTC4 as a TBK1 Interactor and a Positive Regulator of SeV-induced Innate Immunity. Proteomics. PMID 29251827 DOI: 10.1002/pmic.201700403 |
0.373 |
|
2017 |
Wei J, Guo W, Lian H, Yang Q, Lin H, Li S, Shu HB. SNX8 mediates IFNγ-triggered noncanonical signaling pathway and host defense against Listeria monocytogenes. Proceedings of the National Academy of Sciences of the United States of America. 114: 13000-13005. PMID 29180417 DOI: 10.1073/pnas.1713462114 |
0.38 |
|
2017 |
Luo WW, Li S, Li C, Zheng ZQ, Cao P, Tong Z, Lian H, Wang SY, Shu HB, Wang YY. iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA. Plos Pathogens. 13: e1006693. PMID 29155878 DOI: 10.1371/journal.ppat.1006693 |
0.565 |
|
2017 |
Yan BR, Zhou L, Hu MM, Li M, Lin H, Yang Y, Wang YY, Shu HB. PKACs attenuate innate antiviral response by phosphorylating VISA and priming it for MARCH5-mediated degradation. Plos Pathogens. 13: e1006648. PMID 28934360 DOI: 10.1371/journal.ppat.1006648 |
0.361 |
|
2017 |
Yang Q, Liu TT, Lin H, Zhang M, Wei J, Luo WW, Hu YH, Zhong B, Hu MM, Shu HB. TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responses. Plos Pathogens. 13: e1006600. PMID 28898289 DOI: 10.1371/journal.ppat.1006600 |
0.413 |
|
2017 |
Qin Y, Li M, Zhou SL, Yin W, Bian Z, Shu HB. SPI-2/CrmA inhibits IFN-β induction by targeting TBK1/IKKε. Scientific Reports. 7: 10495. PMID 28874755 DOI: 10.1038/s41598-017-11016-3 |
0.491 |
|
2017 |
Luo WW, Shu HB. Emerging roles of rhomboid-like pseudoproteases in inflammatory and innate immune responses. Febs Letters. PMID 28815577 DOI: 10.1002/1873-3468.12796 |
0.359 |
|
2017 |
Ye W, Hu MM, Lei CQ, Zhou Q, Lin H, Sun MS, Shu HB. TRIM8 Negatively Regulates TLR3/4-Mediated Innate Immune Response by Blocking TRIF-TBK1 Interaction. Journal of Immunology (Baltimore, Md. : 1950). PMID 28747347 DOI: 10.4049/Jimmunol.1601647 |
0.393 |
|
2017 |
Sun H, Zhang Q, Jing YY, Zhang M, Wang HY, Cai Z, Liuyu T, Zhang ZD, Xiong TC, Wu Y, Zhu QY, Yao J, Shu HB, Lin D, Zhong B. USP13 negatively regulates antiviral responses by deubiquitinating STING. Nature Communications. 8: 15534. PMID 28534493 DOI: 10.1038/ncomms15534 |
0.499 |
|
2017 |
Jiang LQ, Xia T, Hu YH, Sun MS, Yan S, Lei CQ, Shu HB, Guo JH, Liu Y. IFITM3 inhibits virus-triggered induction of type I interferon by mediating autophagosome-dependent degradation of IRF3. Cellular & Molecular Immunology. PMID 28435159 DOI: 10.1038/Cmi.2017.15 |
0.538 |
|
2017 |
Hu MM, Liao CY, Yang Q, Xie XQ, Shu HB. Innate immunity to RNA virus is regulated by temporal and reversible sumoylation of RIG-I and MDA5. The Journal of Experimental Medicine. PMID 28250012 DOI: 10.1084/jem.20161015 |
0.505 |
|
2017 |
Hu MM, Shu HB. Multifaceted roles of TRIM38 in innate immune and inflammatory responses. Cellular & Molecular Immunology. PMID 28194022 DOI: 10.1038/cmi.2016.66 |
0.426 |
|
2017 |
Fu YZ, Su S, Gao YQ, Wang PP, Huang ZF, Hu MM, Luo WW, Li S, Luo MH, Wang YY, Shu HB. Human Cytomegalovirus Tegument Protein UL82 Inhibits STING-Mediated Signaling to Evade Antiviral Immunity. Cell Host & Microbe. PMID 28132838 DOI: 10.1016/j.chom.2017.01.001 |
0.47 |
|
2016 |
Wang J, Lei CQ, Ji Y, Zhou H, Ren Y, Peng Q, Zeng Y, Jia Y, Ge J, Zhong B, Li Y, Wei J, Shu HB, Zhu Q. Duck Tembusu Virus Nonstructural Protein 1 Antagonizes IFN-β Signaling Pathways by Targeting VISA. Journal of Immunology (Baltimore, Md. : 1950). PMID 27821666 DOI: 10.4049/Jimmunol.1502317 |
0.505 |
|
2016 |
Zhang M, Zhang MX, Zhang Q, Zhu GF, Yuan L, Zhang DE, Zhu Q, Yao J, Shu HB, Zhong B. USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA. Cell Research. PMID 27801882 DOI: 10.1038/cr.2016.125 |
0.494 |
|
2016 |
Zhu Z, Wang G, Yang F, Cao W, Mao R, Du X, Zhang X, Li C, Li D, Zhang K, Shu H, Liu X, Zheng H. Foot-and-mouth disease virus viroporin 2B antagonizes RIG-I mediated antiviral effects by inhibition of its protein expression. Journal of Virology. PMID 27707918 DOI: 10.1128/JVI.01310-16 |
0.36 |
|
2016 |
Hu MM, Yang Q, Xie XQ, Liao CY, Lin H, Liu TT, Yin L, Shu HB. Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus. Immunity. PMID 27637147 DOI: 10.1016/j.immuni.2016.08.014 |
0.483 |
|
2016 |
Luo WW, Li S, Li C, Lian H, Yang Q, Zhong B, Shu HB. iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING. Nature Immunology. PMID 27428826 DOI: 10.1038/ni.3510 |
0.447 |
|
2016 |
Chen LT, Hu MM, Xu ZS, Liu Y, Shu HB. MSX1 Modulates RLR-Mediated Innate Antiviral Signaling by Facilitating Assembly of TBK1-Associated Complexes. Journal of Immunology (Baltimore, Md. : 1950). PMID 27194789 DOI: 10.4049/jimmunol.1600039 |
0.534 |
|
2016 |
Liu TT, Yang Q, Li M, Zhong B, Ran Y, Liu LL, Yang Y, Wang YY, Shu HB. LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner. Journal of Immunology (Baltimore, Md. : 1950). PMID 27183626 DOI: 10.4049/jimmunol.1600212 |
0.533 |
|
2016 |
Ren Y, Zhao Y, Lin D, Xu X, Zhu Q, Yao J, Shu HB, Zhong B. The type I interferon-IRF7 axis mediates transcriptional expression of Usp25. The Journal of Biological Chemistry. PMID 27129230 DOI: 10.1074/jbc.M116.718080 |
0.439 |
|
2016 |
Li D, Wei J, Yang F, Liu HN, Zhu ZX, Cao WJ, Li S, Liu XT, Zheng HX, Shu HB. Foot-and-mouth disease virus structural protein VP3 degrades Janus kinase 1 to inhibit IFN-γ signal transduction pathways. Cell Cycle (Georgetown, Tex.). 0. PMID 26901336 DOI: 10.1080/15384101.2016.1151584 |
0.423 |
|
2016 |
Li D, Lei C, Xu Z, Yang F, Liu H, Zhu Z, Li S, Liu X, Shu H, Zheng H. Foot-and-mouth disease virus non-structural protein 3A inhibits the interferon-β signaling pathway. Scientific Reports. 6: 21888. PMID 26883855 DOI: 10.1038/Srep21888 |
0.302 |
|
2016 |
Li D, Yang W, Yang F, Liu H, Zhu Z, Lian K, Lei C, Li S, Liu X, Zheng H, Shu H. The VP3 structural protein of foot-and-mouth disease virus inhibits the IFN-β signaling pathway. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26813975 DOI: 10.1096/Fj.15-281410 |
0.439 |
|
2015 |
Li S, Zhu M, Pan R, Fang T, Cao YY, Chen S, Zhao X, Lei CQ, Guo L, Chen Y, Li CM, Jokitalo E, Yin Y, Shu HB, Guo D. The tumor suppressor PTEN has a critical role in antiviral innate immunity. Nature Immunology. PMID 26692175 DOI: 10.1038/Ni.3311 |
0.369 |
|
2015 |
An T, Li S, Pan W, Tien P, Zhong B, Shu HB, Wu S. DYRK2 Negatively Regulates Type I Interferon Induction by Promoting TBK1 Degradation via Ser527 Phosphorylation. Plos Pathogens. 11: e1005179. PMID 26407194 DOI: 10.1371/journal.ppat.1005179 |
0.563 |
|
2015 |
Hu MM, Xie XQ, Yang Q, Liao CY, Ye W, Lin H, Shu HB. TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms. Journal of Immunology (Baltimore, Md. : 1950). PMID 26392463 DOI: 10.4049/jimmunol.1500859 |
0.423 |
|
2015 |
Lin D, Zhang M, Zhang MX, Ren Y, Zhao Q, Jin J, Pan Z, Wu M, Shu HB, Dong C, Zhong B. Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6. Proceedings of the National Academy of Sciences of the United States of America. PMID 26305951 DOI: 10.1073/pnas.1509968112 |
0.523 |
|
2015 |
Wei J, Lian H, Zhong B, Shu HB. Parafibromin Is a Component of IFN-γ-Triggered Signaling Pathways That Facilitates JAK1/2-Mediated Tyrosine Phosphorylation of STAT1. Journal of Immunology (Baltimore, Md. : 1950). 195: 2870-8. PMID 26232434 DOI: 10.4049/jimmunol.1501111 |
0.376 |
|
2015 |
Zhou MT, Qin Y, Li M, Chen C, Chen X, Shu HB, Guo L. Quantitative proteomics reveals the roles of peroxisome-associated proteins in anti-viral innate immune responses. Molecular & Cellular Proteomics : McP. PMID 26124285 DOI: 10.1074/mcp.M115.048413 |
0.377 |
|
2015 |
Lei CQ, Zhang Y, Li M, Jiang LQ, Zhong B, Kim YH, Shu HB. ECSIT bridges RIG-I-like receptors to VISA in signaling events of innate antiviral responses. Journal of Innate Immunity. 7: 153-64. PMID 25228397 DOI: 10.1159/000365971 |
0.535 |
|
2014 |
Luo WW, Lian H, Zhong B, Shu HB, Li S. Krüppel-like factor 4 negatively regulates cellular antiviral immune response. Cellular & Molecular Immunology. PMID 25531393 DOI: 10.1038/cmi.2014.125 |
0.378 |
|
2014 |
Zhou Q, Lin H, Wang S, Wang S, Ran Y, Liu Y, Ye W, Xiong X, Zhong B, Shu HB, Wang YY. The ER-associated protein ZDHHC1 is a positive regulator of DNA virus-triggered, MITA/STING-dependent innate immune signaling. Cell Host & Microbe. 16: 450-61. PMID 25299331 DOI: 10.1016/j.chom.2014.09.006 |
0.51 |
|
2014 |
Qin Y, Zhou MT, Hu MM, Hu YH, Zhang J, Guo L, Zhong B, Shu HB. RNF26 temporally regulates virus-triggered type I interferon induction by two distinct mechanisms. Plos Pathogens. 10: e1004358. PMID 25254379 DOI: 10.1371/Journal.Ppat.1004358 |
0.568 |
|
2014 |
Ran Y, Shu HB, Wang YY. MITA/STING: a central and multifaceted mediator in innate immune response. Cytokine & Growth Factor Reviews. 25: 631-9. PMID 24929887 DOI: 10.1016/j.cytogfr.2014.05.003 |
0.382 |
|
2014 |
Yan J, Li Q, Mao AP, Hu MM, Shu HB. TRIM4 modulates type I interferon induction and cellular antiviral response by targeting RIG-I for K63-linked ubiquitination. Journal of Molecular Cell Biology. 6: 154-63. PMID 24755855 DOI: 10.1093/jmcb/mju005 |
0.537 |
|
2014 |
Zhang L, Mo J, Swanson KV, Wen H, Petrucelli A, Gregory SM, Zhang Z, Schneider M, Jiang Y, Fitzgerald KA, Ouyang S, Liu ZJ, Damania B, Shu HB, Duncan JA, et al. NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING. Immunity. 40: 329-41. PMID 24560620 DOI: 10.1016/J.Immuni.2014.01.010 |
0.414 |
|
2014 |
Zhang J, Hu MM, Shu HB, Li S. Death-associated protein kinase 1 is an IRF3/7-interacting protein that is involved in the cellular antiviral immune response. Cellular & Molecular Immunology. 11: 245-52. PMID 24531619 DOI: 10.1038/Cmi.2013.65 |
0.567 |
|
2013 |
Liu Z, Wu SW, Lei CQ, Zhou Q, Li S, Shu HB, Wang YY. Heat shock cognate 71 (HSC71) regulates cellular antiviral response by impairing formation of VISA aggregates. Protein & Cell. 4: 373-82. PMID 23636689 DOI: 10.1007/S13238-013-3902-3 |
0.507 |
|
2013 |
Ding Q, Cao X, Lu J, Huang B, Liu YJ, Kato N, Shu HB, Zhong J. Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity. Journal of Hepatology. 59: 52-8. PMID 23542348 DOI: 10.1016/j.jhep.2013.03.019 |
0.334 |
|
2013 |
Lei CQ, Zhang Y, Xia T, Jiang LQ, Zhong B, Shu HB. FoxO1 negatively regulates cellular antiviral response by promoting degradation of IRF3. The Journal of Biological Chemistry. 288: 12596-604. PMID 23532851 DOI: 10.1074/Jbc.M112.444794 |
0.533 |
|
2013 |
Yang Y, Liao B, Wang S, Yan B, Jin Y, Shu HB, Wang YY. E3 ligase WWP2 negatively regulates TLR3-mediated innate immune response by targeting TRIF for ubiquitination and degradation. Proceedings of the National Academy of Sciences of the United States of America. 110: 5115-20. PMID 23479606 DOI: 10.1073/pnas.1220271110 |
0.431 |
|
2013 |
Chen H, Li Y, Zhang J, Ran Y, Wei J, Yang Y, Shu HB. RAVER1 is a coactivator of MDA5-mediated cellular antiviral response. Journal of Molecular Cell Biology. 5: 111-9. PMID 23390309 DOI: 10.1093/Jmcb/Mjt006 |
0.528 |
|
2013 |
Zheng H, Li Q, Chen R, Zhang J, Ran Y, He X, Li S, Shu HB. The dual-specificity phosphatase DUSP14 negatively regulates tumor necrosis factor- and interleukin-1-induced nuclear factor-κB activation by dephosphorylating the protein kinase TAK1. The Journal of Biological Chemistry. 288: 819-25. PMID 23229544 DOI: 10.1074/Jbc.M112.412643 |
0.334 |
|
2012 |
Li Y, He X, Wang S, Shu HB, Liu Y. USP2a positively regulates TCR-induced NF-κB activation by bridging MALT1-TRAF6. Protein & Cell. 4: 62-70. PMID 23264041 DOI: 10.1007/s13238-012-2120-8 |
0.313 |
|
2012 |
Wang YY, Ran Y, Shu HB. Linear ubiquitination of NEMO brakes the antiviral response. Cell Host & Microbe. 12: 129-31. PMID 22901534 DOI: 10.1016/j.chom.2012.07.006 |
0.406 |
|
2012 |
Li Y, Chen R, Zhou Q, Xu Z, Li C, Wang S, Mao A, Zhang X, He W, Shu HB. LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 11770-5. PMID 22745163 DOI: 10.1073/pnas.1203405109 |
0.349 |
|
2012 |
Zhang J, Hu M, Wang Y, Shu H. TRIM32 Protein Modulates Type I Interferon Induction and Cellular Antiviral Response by Targeting MITA/STING Protein for K63-linked Ubiquitination Journal of Biological Chemistry. 287: 28646-28655. PMID 22745133 DOI: 10.1074/Jbc.M112.362608 |
0.511 |
|
2012 |
He X, Li Y, Li C, Liu LJ, Zhang XD, Liu Y, Shu HB. USP2a negatively regulates IL-1β- and virus-induced NF-κB activation by deubiquitinating TRAF6. Journal of Molecular Cell Biology. 5: 39-47. PMID 22611252 DOI: 10.1093/jmcb/mjs024 |
0.318 |
|
2012 |
Liu Y, Song R, Gao Y, Li Y, Wang S, Liu HY, Wang Y, Hu YH, Shu HB. Protein kinase C-δ negatively regulates T cell receptor-induced NF-κB activation by inhibiting the assembly of CARMA1 signalosome. The Journal of Biological Chemistry. 287: 20081-7. PMID 22528498 DOI: 10.1074/jbc.M111.335463 |
0.345 |
|
2011 |
Li Q, Yan J, Mao AP, Li C, Ran Y, Shu HB, Wang YY. Tripartite motif 8 (TRIM8) modulates TNFα- and IL-1β-triggered NF-κB activation by targeting TAK1 for K63-linked polyubiquitination. Proceedings of the National Academy of Sciences of the United States of America. 108: 19341-6. PMID 22084099 DOI: 10.1073/pnas.1110946108 |
0.364 |
|
2011 |
Ran Y, Liu TT, Zhou Q, Li S, Mao AP, Li Y, Liu LJ, Cheng JK, Shu HB. SENP2 negatively regulates cellular antiviral response by deSUMOylating IRF3 and conditioning it for ubiquitination and degradation. Journal of Molecular Cell Biology. 3: 283-92. PMID 22028379 DOI: 10.1093/jmcb/mjr020 |
0.498 |
|
2010 |
Zhong B, Wang YY, Shu HB. Regulation of virus-triggered type I interferon signaling by cellular and viral proteins. Frontiers in Biology. 5: 12-31. PMID 32215003 DOI: 10.1007/s11515-010-0013-x |
0.421 |
|
2010 |
Lei CQ, Zhong B, Zhang Y, Zhang J, Wang S, Shu HB. Glycogen synthase kinase 3β regulates IRF3 transcription factor-mediated antiviral response via activation of the kinase TBK1. Immunity. 33: 878-89. PMID 21145761 DOI: 10.1016/J.Immuni.2010.11.021 |
0.536 |
|
2010 |
Zhong B, Zhang Y, Tan B, Liu TT, Wang YY, Shu HB. The E3 ubiquitin ligase RNF5 targets virus-induced signaling adaptor for ubiquitination and degradation. Journal of Immunology (Baltimore, Md. : 1950). 184: 6249-55. PMID 20483786 DOI: 10.4049/jimmunol.0903748 |
0.511 |
|
2010 |
Chen R, Zhang L, Zhong B, Tan B, Liu Y, Shu HB. The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling. Cell Research. 20: 802-11. PMID 20368735 DOI: 10.1038/cr.2010.41 |
0.444 |
|
2010 |
Han KJ, Yang Y, Xu LG, Shu HB. Analysis of a TIR-less splice variant of TRIF reveals an unexpected mechanism of TLR3-mediated signaling Journal of Biological Chemistry. 285: 12543-12550. PMID 20200155 DOI: 10.1074/jbc.M109.072231 |
0.346 |
|
2010 |
Mao AP, Li S, Zhong B, Li Y, Yan J, Li Q, Teng C, Shu HB. Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response. The Journal of Biological Chemistry. 285: 9470-6. PMID 20097753 DOI: 10.1074/jbc.M109.071043 |
0.529 |
|
2010 |
Li S, Zheng H, Mao AP, Zhong B, Li Y, Liu Y, Gao Y, Ran Y, Tien P, Shu HB. Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6. The Journal of Biological Chemistry. 285: 4291-7. PMID 19996094 DOI: 10.1074/jbc.M109.074971 |
0.485 |
|
2009 |
Li Y, Li C, Xue P, Zhong B, Mao AP, Ran Y, Chen H, Wang YY, Yang F, Shu HB. ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response. Proceedings of the National Academy of Sciences of the United States of America. 106: 7945-50. PMID 19416887 DOI: 10.1073/pnas.0900818106 |
0.473 |
|
2009 |
Zhong B, Zhang L, Lei C, Li Y, Mao AP, Yang Y, Wang YY, Zhang XL, Shu HB. The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA. Immunity. 30: 397-407. PMID 19285439 DOI: 10.1016/J.Immuni.2009.01.008 |
0.52 |
|
2008 |
Zhong B, Yang Y, Li S, Wang YY, Li Y, Diao F, Lei C, He X, Zhang L, Tien P, Shu HB. The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity. 29: 538-50. PMID 18818105 DOI: 10.1016/J.Immuni.2008.09.003 |
0.506 |
|
2008 |
Zhang M, Tian Y, Wang RP, Gao D, Zhang Y, Diao FC, Chen DY, Zhai ZH, Shu HB. Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3. Cell Research. 18: 1096-104. PMID 18711448 DOI: 10.1038/cr.2008.277 |
0.518 |
|
2007 |
Diao F, Li S, Tian Y, Zhang M, Xu LG, Zhang Y, Wang RP, Chen D, Zhai Z, Zhong B, Tien P, Shu HB. Negative regulation of MDA5- but not RIG-I-mediated innate antiviral signaling by the dihydroxyacetone kinase. Proceedings of the National Academy of Sciences of the United States of America. 104: 11706-11. PMID 17600090 DOI: 10.1073/pnas.0700544104 |
0.49 |
|
2006 |
Zhong B, Tien P, Shu HB. Innate immune responses: crosstalk of signaling and regulation of gene transcription. Virology. 352: 14-21. PMID 16753195 DOI: 10.1016/j.virol.2006.04.029 |
0.377 |
|
2006 |
Zha J, Han KJ, Xu LG, He W, Zhou Q, Chen D, Zhai Z, Shu HB. The Ret finger protein inhibits signaling mediated by the noncanonical and canonical IkappaB kinase family members. Journal of Immunology (Baltimore, Md. : 1950). 176: 1072-80. PMID 16393995 DOI: 10.4049/Jimmunol.176.2.1072 |
0.422 |
|
2006 |
Su X, Li S, Meng M, Qian W, Xie W, Chen D, Zhai Z, Shu HB. TNF receptor-associated factor-1 (TRAF1) negatively regulates Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF)-mediated signaling. European Journal of Immunology. 36: 199-206. PMID 16323247 DOI: 10.1002/Eji.200535415 |
0.426 |
|
2005 |
Huang J, Liu T, Xu LG, Chen D, Zhai Z, Shu HB. SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways. The Embo Journal. 24: 4018-28. PMID 16281057 DOI: 10.1038/sj.emboj.7600863 |
0.446 |
|
2005 |
Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB. VISA is an adapter protein required for virus-triggered IFN-beta signaling. Molecular Cell. 19: 727-40. PMID 16153868 DOI: 10.1016/j.molcel.2005.08.014 |
0.43 |
|
2005 |
Li L, Bin LH, Li F, Liu Y, Chen D, Zhai Z, Shu HB. TRIP6 is a RIP2-associated common signaling component of multiple NF-kappaB activation pathways. Journal of Cell Science. 118: 555-63. PMID 15657077 DOI: 10.1242/jcs.01641 |
0.317 |
|
2004 |
Wang YY, Li L, Han KJ, Zhai Z, Shu HB. A20 is a potent inhibitor of TLR3- and Sendai virus-induced activation of NF-kappaB and ISRE and IFN-beta promoter. Febs Letters. 576: 86-90. PMID 15474016 DOI: 10.1016/j.febslet.2004.08.071 |
0.394 |
|
2004 |
Han KJ, Su X, Xu LG, Bin LH, Zhang J, Shu HB. Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways. The Journal of Biological Chemistry. 279: 15652-61. PMID 14739303 DOI: 10.1074/jbc.M311629200 |
0.416 |
|
2002 |
Zhou J, Shu HB, Joshi HC. Regulation of tubulin synthesis and cell cycle progression in mammalian cells by gamma-tubulin-mediated microtubule nucleation. Journal of Cellular Biochemistry. 84: 472-83. PMID 11813253 DOI: 10.1002/Jcb.10033 |
0.458 |
|
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