Raymond Pierce

Affiliations: 
Lille 2 
Area:
, Schistosomiasis, Histone Deacetylase, Mansoni sirtuin
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"Raymond Pierce"

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Catherine Roche-Lestienne grad student 1995 University Lille 1
Benjamin Bertin grad student 2004 Lille 2
Frédérik Oger grad student 2006 Lille 2
Florence Dubois grad student 2009 Lille 2
Alvaro Baeza Garcia grad student 2010 Lille 2
Julien Lancelot grad student 2013 Lille 2
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Publications

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Coelho FS, Gava SG, Andrade LF, et al. (2023) coactivator associated arginine methyltransferase 1 (SmCARM1) effect on parasite reproduction. Frontiers in Microbiology. 14: 1079855
Ghazy E, Abdelsalam M, Robaa D, et al. (2022) Histone Deacetylase (HDAC) Inhibitors for the Treatment of Schistosomiasis. Pharmaceuticals (Basel, Switzerland). 15
Marek M, Ramos-Morales E, Picchi-Constante GFA, et al. (2021) Species-selective targeting of pathogens revealed by the atypical structure and active site of Trypanosoma cruzi histone deacetylase DAC2. Cell Reports. 37: 110129
Pagliazzo L, Caby S, Lancelot J, et al. (2021) Histone deacetylase 8 interacts with the GTPase SmRho1 in Schistosoma mansoni. Plos Neglected Tropical Diseases. 15: e0009503
Ghazy E, Heimburg T, Lancelot J, et al. (2021) Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasis. European Journal of Medicinal Chemistry. 225: 113745
Ângelo de Souza L, Silva E Bastos M, de Melo Agripino J, et al. (2020) Histone deacetylases inhibitors as new potential drugs against Leishmania braziliensis, the main causative agent of new world tegumentary leishmaniasis. Biochemical Pharmacology. 180: 114191
Coutinho Carneiro V, de Abreu da Silva IC, Amaral MS, et al. (2020) Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni. Plos Neglected Tropical Diseases. 14: e0008332
Kalinin DV, Jana SK, Pfafenrot M, et al. (2020) Front Cover: Structure‐Based Design, Synthesis, and Biological Evaluation of Triazole‐Based smHDAC8 Inhibitors (ChemMedChem 7/2020) Chemmedchem. 15: 559-559
Holl R, Kalinin DV, Jana SK, et al. (2019) Structure-Based Design, Synthesis, and Biological Evaluation of Triazole-Based smHDAC8 Inhibitors. Chemmedchem
Monaldi D, Rotili D, Lancelot J, et al. (2019) Structure-Reactivity Relationships on Substrates and Inhibitors of the Lysine Deacylase Sirtuin 2 from Schistosoma Mansoni (SmSirt2). Journal of Medicinal Chemistry
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