| Year |
Citation |
Score |
| 2021 |
Garai S, Schaffer PC, Laprairie RB, Janero DR, Pertwee RG, Straiker A, Thakur GA. Design, synthesis, and pharmacological profiling of cannabinoid 1 receptor allosteric modulators: Preclinical efficacy of C2-group GAT211 congeners for reducing intraocular pressure. Bioorganic & Medicinal Chemistry. 50: 116421. PMID 34634617 DOI: 10.1016/j.bmc.2021.116421 |
0.371 |
|
| 2021 |
Pismataro MC, Horenstein NA, Stokes C, Dallanoce C, Thakur GA, Papke RL. Stable desensitization of α nicotinic acetylcholine receptors by NS6740 requires interaction with S36 in the orthosteric agonist binding site. European Journal of Pharmacology. 905: 174179. PMID 34004208 DOI: 10.1016/j.ejphar.2021.174179 |
0.422 |
|
| 2021 |
Mizrachi T, Marsha O, Brusin K, Ben-David Y, Thakur GA, Vaknin-Dembinsky A, Treinin M, Brenner T. Suppression of neuroinflammation by an allosteric agonist and positive allosteric modulator of the α7 nicotinic acetylcholine receptor GAT107. Journal of Neuroinflammation. 18: 99. PMID 33902624 DOI: 10.1186/s12974-021-02149-4 |
0.323 |
|
| 2021 |
Garai S, Leo LM, Szczesniak AM, Hurst DP, Schaffer PC, Zagzoog A, Black T, Deschamps JR, Miess E, Schulz S, Janero DR, Straiker A, Pertwee RG, Abood ME, Kelly MEM, ... ... Thakur GA, et al. Discovery of a Biased Allosteric Modulator for Cannabinoid 1 Receptor: Preclinical Anti-Glaucoma Efficacy. Journal of Medicinal Chemistry. PMID 33826336 DOI: 10.1021/acs.jmedchem.1c00040 |
0.358 |
|
| 2021 |
Jiang S, Iliopoulos-Tsoutsouvas C, Tong F, Brust CA, Keenan CM, Raghav JG, Hua T, Wu S, Ho JH, Wu Y, Grim TW, Zvonok N, Thakur GA, Liu ZJ, Sharkey KA, et al. Novel Functionalized Cannabinoid Receptor Probes: Development of Exceptionally Potent Agonists. Journal of Medicinal Chemistry. PMID 33761251 DOI: 10.1021/acs.jmedchem.0c02053 |
0.387 |
|
| 2021 |
McElroy DL, Roebuck AJ, Scott GA, Greba Q, Garai S, Denovan-Wright EM, Thakur GA, Laprairie RB, Howland JG. Antipsychotic potential of the type 1 cannabinoid receptor positive allosteric modulator GAT211: preclinical in vitro and in vivo studies. Psychopharmacology. PMID 33442771 DOI: 10.1007/s00213-020-05755-x |
0.357 |
|
| 2020 |
Schaffer PC, Kulkarni PM, Janero DR, Thakur GA. Focused structure-activity relationship profiling around the 2-phenylindole scaffold of a cannabinoid type-1 receptor agonist-positive allosteric modulator: site-III aromatic-ring congeners with enhanced activity and solubility. Bioorganic & Medicinal Chemistry. 28: 115727. PMID 33065437 DOI: 10.1016/j.bmc.2020.115727 |
0.345 |
|
| 2020 |
Papke RL, Garai S, Stokes C, Horenstein NA, Zimmerman AD, Abboud KA, Thakur GA. Differing activity profiles of the stereoisomers of 2,3,5,6TMP-TQS, a putative silent allosteric modulator of α7nAChR. Molecular Pharmacology. PMID 32690627 DOI: 10.1124/Mol.120.119958 |
0.384 |
|
| 2020 |
Thapa D, Cairns EA, Szczesniak AM, Kulkarni PM, Straiker AJ, Thakur GA, Kelly MEM. Allosteric Cannabinoid Receptor 1 (CB1) Ligands Reduce Ocular Pain and Inflammation. Molecules (Basel, Switzerland). 25. PMID 31968549 DOI: 10.3390/molecules25020417 |
0.475 |
|
| 2019 |
Garai S, Kulkarni PM, Schaffer PC, Leo L, Brandt AL, Zagzoog A, Black T, Lin X, Hurst DP, Janero DR, Abood ME, Zimmowitch A, Straiker A, Pertwee RG, Kelly M, ... ... Thakur GA, et al. Application of Fluorine- And Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of CB1 Receptor Positive Allosteric Modulators. Journal of Medicinal Chemistry. PMID 31756109 DOI: 10.1021/Acs.Jmedchem.9B01142 |
0.445 |
|
| 2019 |
Laprairie RB, Mohamed KA, Zagzoog A, Kelly MEM, Stevenson LA, Pertwee R, Denovan-Wright EM, Thakur GA. Indomethacin Enhances Type 1 Cannabinoid Receptor Signaling. Frontiers in Molecular Neuroscience. 12: 257. PMID 31680861 DOI: 10.3389/Fnmol.2019.00257 |
0.369 |
|
| 2019 |
Salaga M, Binienda A, Tichkule RB, Thakur GA, Makriyannis A, Storr M, Fichna J. Corrigendum to "The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome" [Eur. J. Pharmacol. (2018), 836 34-43]. European Journal of Pharmacology. 172656. PMID 31519354 DOI: 10.1016/J.Ejphar.2019.172656 |
0.719 |
|
| 2019 |
Hurst DP, Garai S, Kulkarni PM, Schaffer PC, Reggio PH, Thakur GA. Identification of CB1 Receptor Allosteric Sites Using Force-Biased MMC Simulated Annealing and Validation by Structure-Activity Relationship Studies. Acs Medicinal Chemistry Letters. 10: 1216-1221. PMID 31413808 DOI: 10.1021/acsmedchemlett.9b00256 |
0.381 |
|
| 2019 |
Gulsevin A, Papke RL, Stokes C, Thakur GA, Quadri M, Horenstein N. Allosteric agonism of α7 nicotinic acetylcholine receptors. Molecular Pharmacology. PMID 30944209 DOI: 10.1124/Mol.119.115758 |
0.347 |
|
| 2019 |
Laprairie RB, Bagher AM, Rourke JL, Zrein A, Cairns EA, Kelly MEM, Sinal CJ, Kulkarni PM, Thakur GA, Denovan-Wright EM. Positive allosteric modulation of the type 1 cannabinoid receptor reduces the signs and symptoms of Huntington's disease in the R6/2 mouse model. Neuropharmacology. PMID 30940536 DOI: 10.1016/J.Neuropharm.2019.03.033 |
0.32 |
|
| 2018 |
Salaga M, Binienda A, Tichkule RB, Thakur GA, Makriyannis A, Storr M, Fichna J. The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome. European Journal of Pharmacology. PMID 30121173 DOI: 10.1016/J.Ejphar.2018.08.016 |
0.731 |
|
| 2017 |
Mitjavila J, Yin D, Kulkarni PM, Zanato C, Thakur GA, Ross R, Greig I, Mackie K, Straiker A. Enantiomer-specific positive allosteric modulation of CB1 signaling in autaptic hippocampal neurons. Pharmacological Research. PMID 29158048 DOI: 10.1016/j.phrs.2017.11.019 |
0.315 |
|
| 2017 |
Slivicki RA, Xu Z, Kulkarni PM, Pertwee RG, Mackie K, Thakur GA, Hohmann AG. Positive Allosteric Modulation of Cannabinoid Receptor Type 1 Suppresses Pathological Pain Without Producing Tolerance or Dependence. Biological Psychiatry. PMID 28823711 DOI: 10.1016/J.Biopsych.2017.06.032 |
0.464 |
|
| 2017 |
Kulkarni AR, Garai S, Janero DR, Thakur GA. Design and Synthesis of Cannabinoid 1 Receptor (CB1R) Allosteric Modulators: Drug Discovery Applications. Methods in Enzymology. 593: 281-315. PMID 28750808 DOI: 10.1016/bs.mie.2017.06.018 |
0.456 |
|
| 2017 |
Cairns EA, Szczesniak AM, Straiker AJ, Kulkarni PM, Pertwee RG, Thakur GA, Baldridge WH, Kelly MEM. The In Vivo Effects of the CB1-Positive Allosteric Modulator GAT229 on Intraocular Pressure in Ocular Normotensive and Hypertensive Mice. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 28719234 DOI: 10.1089/jop.2017.0037 |
0.367 |
|
| 2017 |
Donvito G, Bagdas D, Toma W, Rahimpour E, Jackson A, Meade JA, AlSharari S, Kulkarni AR, Ivy Carroll F, Lichtman AH, Papke RL, Thakur GA, Imad Damaj M. The interaction between alpha 7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α represents a new antinociceptive signaling pathway in mice. Experimental Neurology. PMID 28606623 DOI: 10.1016/J.Expneurol.2017.06.014 |
0.362 |
|
| 2017 |
Papke RL, Stokes C, Damaj MI, Thakur GA, Manther K, Treinin M, Bagdas D, Kulkarni AR, Horenstein NA. Persistent activation of α7 nAChRs associated with stable induction of different desensitized states. British Journal of Pharmacology. PMID 28477386 DOI: 10.1111/Bph.13851 |
0.304 |
|
| 2017 |
Zhou H, Peng Y, Halikhedkar A, Fan P, Janero DR, Thakur GA, Mercier RW, Sun X, Ma X, Makriyannis A. Human Cannabinoid Receptor 2 Ligand-interaction Motif: Transmembrane Helix 2 Cysteine, C2.59(89), as Determinant of Classical Cannabinoid Agonist Activity and Binding Pose. Acs Chemical Neuroscience. PMID 28220706 DOI: 10.1021/Acschemneuro.7B00003 |
0.335 |
|
| 2017 |
Laprairie RB, Kulkarni PM, Deschamps JR, Kelly ME, Janero DR, Cascio MG, Stevenson LA, Pertwee RG, Kenakin T, Denovan-Wright EM, Thakur GA. Enantio-specific Allosteric Modulation of Cannabinoid 1 Receptor. Acs Chemical Neuroscience. PMID 28103441 DOI: 10.1021/Acschemneuro.6B00310 |
0.448 |
|
| 2017 |
Kyte SL, Toma W, Thakur G, Damaj MI, Gewirtz DA. Abstract 986: Targeting nicotinic acetylcholine receptors for the prevention and reversal of chemotherapy-induced peripheral neuropathy Cancer Research. 77: 986-986. DOI: 10.1158/1538-7445.Am2017-986 |
0.407 |
|
| 2016 |
Janero DR, Thakur GA. Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as a discovery target. Expert Opinion On Drug Discovery. PMID 27712124 DOI: 10.1080/17460441.2016.1245289 |
0.42 |
|
| 2016 |
Järbe TU, LeMay BJ, Thakur GA, Makriyannis A. A High Efficacy Cannabinergic Ligand (AM4054) used as a Discriminative Stimulus: Generalization to other Adamantyl Analogs and Δ(9)-THC in Rats. Pharmacology, Biochemistry, and Behavior. PMID 27264437 DOI: 10.1016/J.Pbb.2016.06.001 |
0.339 |
|
| 2016 |
Bagdas D, Wilkerson JL, Kulkarni A, Toma W, AlSharari S, Gul Z, Lichtman AH, Papke RL, Thakur GA, Imad Damaj M. The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain. British Journal of Pharmacology. PMID 27243753 DOI: 10.1111/Bph.13528 |
0.483 |
|
| 2016 |
Laprairie RB, Kulkarni AR, Kulkarni PM, Hurst DP, Lynch DL, Reggio PH, Janero DR, Pertwee RG, Stevenson LA, Kelly M, Denovan-Wright EM, Thakur GA. MAPPING CANNABINOID RECEPTOR 1 ALLOSTERIC SITE(S): CRITICAL MOLECULAR DETERMINANT AND SIGNALING PROFILE OF GAT100 - A NOVEL, POTENT AND IRREVERSIBLY BINDING PROBE. Acs Chemical Neuroscience. PMID 27046127 DOI: 10.1021/Acschemneuro.6B00041 |
0.461 |
|
| 2016 |
Horenstein NA, Papke RL, Kulkarni AR, Chaturbhuj GU, Stokes C, Manther K, Thakur GA. Critical molecular determinants of α7 nicotinic acetylcholine receptor allosteric activation: separation of direct allosteric activation and positive allosteric modulation. The Journal of Biological Chemistry. PMID 26742843 DOI: 10.1074/Jbc.M115.692392 |
0.368 |
|
| 2015 |
Kulkarni PM, Kulkarni AR, Korde A, Tichkule RB, Laprairie RB, Denovan-Wright EM, Zhou H, Janero DR, Zvonok N, Makriyannis A, Cascio MG, Pertwee RG, Thakur GA. Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s). Journal of Medicinal Chemistry. PMID 26529344 DOI: 10.1021/Acs.Jmedchem.5B01303 |
0.707 |
|
| 2015 |
Abalo R, Chen C, Vera G, Fichna J, Thakur GA, López-Pérez AE, Makriyannis A, Martín-Fontelles MI, Storr M. In vitro and non-invasive in vivo effects of the cannabinoid-1 receptor agonist AM841 on gastrointestinal motor function in the rat. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. PMID 26387676 DOI: 10.1111/Nmo.12668 |
0.346 |
|
| 2015 |
Keenan CM, Storr MA, Thakur GA, Wood JT, Wager-Miller J, Straiker A, Eno MR, Nikas SP, Bashashati M, Hu H, Mackie K, Makriyannis A, Sharkey KA. AM841, a covalent cannabinoid ligand, powerfully slows gastrointestinal motility in normal and stressed mice in a peripherally restricted manner. British Journal of Pharmacology. 172: 2406-18. PMID 25572435 DOI: 10.1111/Bph.13069 |
0.512 |
|
| 2015 |
Papke RL, Bagdas D, Kulkarni AR, Gould T, AlSharari SD, Thakur GA, Damaj MI. The analgesic-like properties of the alpha7 nAChR silent agonist NS6740 is associated with non-conducting conformations of the receptor. Neuropharmacology. 91: 34-42. PMID 25497451 DOI: 10.1016/J.Neuropharm.2014.12.002 |
0.41 |
|
| 2015 |
Nikas SP, Sharma R, Paronis CA, Kulkarni S, Thakur GA, Hurst D, Wood JT, Gifford RS, Rajarshi G, Liu Y, Raghav JG, Guo JJ, Järbe TU, Reggio PH, Bergman J, et al. Probing the carboxyester side chain in controlled deactivation (-)-δ(8)-tetrahydrocannabinols. Journal of Medicinal Chemistry. 58: 665-81. PMID 25470070 DOI: 10.1021/Jm501165D |
0.332 |
|
| 2014 |
Fichna J, Bawa M, Thakur GA, Tichkule R, Makriyannis A, McCafferty DM, Sharkey KA, Storr M. Cannabinoids alleviate experimentally induced intestinal inflammation by acting at central and peripheral receptors. Plos One. 9: e109115. PMID 25275313 DOI: 10.1371/Journal.Pone.0109115 |
0.725 |
|
| 2014 |
Gamage TF, Ignatowska-Jankowska BM, Wiley JL, Abdelrahman M, Trembleau L, Greig IR, Thakur GA, Tichkule R, Poklis J, Ross RA, Pertwee RG, Lichtman AH. In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569. Behavioural Pharmacology. 25: 182-5. PMID 24603340 DOI: 10.1097/Fbp.0000000000000027 |
0.733 |
|
| 2014 |
Papke RL, Horenstein NA, Kulkarni AR, Stokes C, Corrie LW, Maeng CY, Thakur GA. The activity of GAT107, an allosteric activator and positive modulator of α7 nicotinic acetylcholine receptors (nAChR), is regulated by aromatic amino acids that span the subunit interface. The Journal of Biological Chemistry. 289: 4515-31. PMID 24362025 DOI: 10.1074/Jbc.M113.524603 |
0.325 |
|
| 2013 |
Sharma R, Nikas SP, Paronis CA, Wood JT, Halikhedkar A, Guo JJ, Thakur GA, Kulkarni S, Benchama O, Raghav JG, Gifford RS, Järbe TU, Bergman J, Makriyannis A. Controlled-deactivation cannabinergic ligands. Journal of Medicinal Chemistry. 56: 10142-57. PMID 24286207 DOI: 10.1021/Jm4016075 |
0.475 |
|
| 2013 |
Chopda GR, Vemuri VK, Sharma R, Thakur GA, Makriyannis A, Paronis CA. Diuretic effects of cannabinoid agonists in mice. European Journal of Pharmacology. 721: 64-9. PMID 24099963 DOI: 10.1016/J.Ejphar.2013.09.053 |
0.431 |
|
| 2013 |
Thakur GA, Bajaj S, Paronis C, Peng Y, Bowman AL, Barak LS, Caron MG, Parrish D, Deschamps JR, Makriyannis A. Novel adamantyl cannabinoids as CB1 receptor probes. Journal of Medicinal Chemistry. 56: 3904-21. PMID 23621789 DOI: 10.1021/Jm4000775 |
0.422 |
|
| 2013 |
McLaughlin PJ, Thakur GA, Vemuri VK, McClure ED, Brown CM, Winston KM, Wood JT, Makriyannis A, Salamone JD. Behavioral effects of the novel potent cannabinoid CB1 agonist AM 4054. Pharmacology, Biochemistry, and Behavior. 109: 16-22. PMID 23603029 DOI: 10.1016/J.Pbb.2013.04.011 |
0.438 |
|
| 2013 |
Kangas BD, Delatte MS, Vemuri VK, Thakur GA, Nikas SP, Subramanian KV, Shukla VG, Makriyannis A, Bergman J. Cannabinoid discrimination and antagonism by CB(1) neutral and inverse agonist antagonists. The Journal of Pharmacology and Experimental Therapeutics. 344: 561-7. PMID 23287700 DOI: 10.1124/Jpet.112.201962 |
0.466 |
|
| 2013 |
Desai RI, Thakur GA, Vemuri VK, Bajaj S, Makriyannis A, Bergman J. Analysis of tolerance and behavioral/physical dependence during chronic CB1 agonist treatment: effects of CB1 agonists, antagonists, and noncannabinoid drugs. The Journal of Pharmacology and Experimental Therapeutics. 344: 319-28. PMID 23197773 DOI: 10.1124/Jpet.112.198374 |
0.301 |
|
| 2013 |
Paronis CA, Thakur GA, Bajaj S, Nikas SP, Vemuri VK, Makriyannis A, Bergman J. Diuretic effects of cannabinoids. The Journal of Pharmacology and Experimental Therapeutics. 344: 8-14. PMID 23019138 DOI: 10.1124/Jpet.112.199331 |
0.368 |
|
| 2012 |
Deng L, Guindon J, Vemuri VK, Thakur GA, White FA, Makriyannis A, Hohmann AG. The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CBâ‚‚ receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy. Molecular Pain. 8: 71. PMID 22998838 DOI: 10.1186/1744-8069-8-71 |
0.447 |
|
| 2012 |
Dixon DD, Tius MA, Thakur GA, Zhou H, Bowman AL, Shukla VG, Peng Y, Makriyannis A. C3-heteroaroyl cannabinoids as photolabeling ligands for the CB2 cannabinoid receptor. Bioorganic & Medicinal Chemistry Letters. 22: 5322-5. PMID 22796181 DOI: 10.1016/J.Bmcl.2012.06.013 |
0.396 |
|
| 2011 |
Teng H, Thakur GA, Makriyannis A. Conformationally constrained analogs of BAY 59-3074 as novel cannabinoid receptor ligands. Bioorganic & Medicinal Chemistry Letters. 21: 5999-6002. PMID 21880487 DOI: 10.1016/J.Bmcl.2011.07.017 |
0.465 |
|
| 2011 |
Szymanski DW, Papanastasiou M, Melchior K, Zvonok N, Mercier RW, Janero DR, Thakur GA, Cha S, Wu B, Karger B, Makriyannis A. Mass spectrometry-based proteomics of human cannabinoid receptor 2: Covalent cysteine 6.47(257)-ligand interaction affording megagonist receptor activation Journal of Proteome Research. 10: 4789-4798. PMID 21861534 DOI: 10.1021/Pr2005583 |
0.341 |
|
| 2009 |
Thakur GA, Tichkule R, Bajaj S, Makriyannis A. Latest advances in cannabinoid receptor agonists. Expert Opinion On Therapeutic Patents. 19: 1647-73. PMID 19939187 DOI: 10.1517/13543770903436505 |
0.711 |
|
| 2008 |
Pei Y, Mercier RW, Anday JK, Thakur GA, Zvonok AM, Hurst D, Reggio PH, Janero DR, Makriyannis A. Ligand-binding architecture of human CB2 cannabinoid receptor: evidence for receptor subtype-specific binding motif and modeling GPCR activation. Chemistry & Biology. 15: 1207-19. PMID 19022181 DOI: 10.1016/J.Chembiol.2008.10.011 |
0.481 |
|
| 2008 |
Rahn EJ, Zvonok AM, Thakur GA, Khanolkar AD, Makriyannis A, Hohmann AG. Selective activation of cannabinoid CB2 receptors suppresses neuropathic nociception induced by treatment with the chemotherapeutic agent paclitaxel in rats. The Journal of Pharmacology and Experimental Therapeutics. 327: 584-91. PMID 18664590 DOI: 10.1124/Jpet.108.141994 |
0.39 |
|
| 2008 |
Kapur A, Samaniego P, Thakur GA, Makriyannis A, Abood ME. Mapping the structural requirements in the CB1 cannabinoid receptor transmembrane helix II for signal transduction. The Journal of Pharmacology and Experimental Therapeutics. 325: 341-8. PMID 18174385 DOI: 10.1124/Jpet.107.133256 |
0.333 |
|
| 2008 |
Bergman J, Delatte MS, Paronis CA, Vemuri K, Thakur GA, Makriyannis A. Some effects of CB1 antagonists with inverse agonist and neutral biochemical properties. Physiology & Behavior. 93: 666-70. PMID 18076956 DOI: 10.1016/J.Physbeh.2007.11.007 |
0.351 |
|
| 2007 |
Khanolkar AD, Lu D, Ibrahim M, Duclos RI, Thakur GA, Malan TP, Porreca F, Veerappan V, Tian X, George C, Parrish DA, Papahatjis DP, Makriyannis A. Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity. Journal of Medicinal Chemistry. 50: 6493-500. PMID 18038967 DOI: 10.1021/Jm070441U |
0.422 |
|
| 2007 |
Kapur A, Hurst DP, Fleischer D, Whitnell R, Thakur GA, Makriyannis A, Reggio PH, Abood ME. Mutation studies of Ser7.39 and Ser2.60 in the human CB1 cannabinoid receptor: evidence for a serine-induced bend in CB1 transmembrane helix 7. Molecular Pharmacology. 71: 1512-24. PMID 17384224 DOI: 10.1124/Mol.107.034645 |
0.38 |
|
| 2006 |
Pavlopoulos S, Thakur GA, Nikas SP, Makriyannis A. Cannabinoid receptors as therapeutic targets. Current Pharmaceutical Design. 12: 1751-69. PMID 16712486 DOI: 10.2174/138161206776873743 |
0.474 |
|
| 2006 |
Thakur GA, Nikas SP, Duclos RI, Makriyannis A. Methods for the synthesis of cannabinergic ligands Methods in Molecular Medicine. 123: 113-148. PMID 16506405 DOI: 10.1385/1-59259-999-0:113 |
0.432 |
|
| 2005 |
Thakur GA, Nikas SP, Li C, Makriyannis A. Structural requirements for cannabinoid receptor probes Handbook of Experimental Pharmacology. 168: 209-246. PMID 16596776 DOI: 10.1007/3-540-26573-2_7 |
0.46 |
|
| 2005 |
Picone RP, Khanolkar AD, Xu W, Ayotte LA, Thakur GA, Hurst DP, Abood ME, Reggio PH, Fournier DJ, Makriyannis A. (-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor. Molecular Pharmacology. 68: 1623-35. PMID 16157695 DOI: 10.1124/Mol.105.014407 |
0.368 |
|
| 2005 |
Thakur GA, Nikas SP, Makriyannis A. CB1 cannabinoid receptor ligands Mini-Reviews in Medicinal Chemistry. 5: 631-640. PMID 16026309 DOI: 10.2174/1389557054368772 |
0.472 |
|
| 2005 |
Lu D, Meng Z, Thakur GA, Fan P, Steed J, Tartal CL, Hurst DP, Reggio PH, Deschamps JR, Parrish DA, George C, Järbe TU, Lamb RJ, Makriyannis A. Adamantyl cannabinoids: a novel class of cannabinergic ligands. Journal of Medicinal Chemistry. 48: 4576-85. PMID 15999995 DOI: 10.1021/Jm058175C |
0.377 |
|
| 2002 |
Thakur GA, Palmer SL, Harrington PE, Stergiades IA, Tius MA, Makriyannis A. Enantiomeric resolution of a novel chiral cannabinoid receptor ligand. Journal of Biochemical and Biophysical Methods. 54: 415-22. PMID 12543516 DOI: 10.1016/S0165-022X(02)00144-6 |
0.451 |
|
| 2002 |
Palmer SL, Thakur GA, Makriyannis A. Cannabinergic ligands. Chemistry and Physics of Lipids. 121: 3-19. PMID 12505686 DOI: 10.1016/S0009-3084(02)00143-3 |
0.483 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2014 |
Rahn EJ, Deng L, Thakur GA, Vemuri K, Zvonok AM, Lai YY, Makriyannis A, Hohmann AG. Prophylactic cannabinoid administration blocks the development of paclitaxel-induced neuropathic nociception during analgesic treatment and following cessation of drug delivery. Molecular Pain. 10: 27. PMID 24742127 DOI: 10.1186/1744-8069-10-27 |
0.299 |
|
| 2018 |
Shekhar A, Thakur GA. Cannabinoid Receptor 1 Positive Allosteric Modulators for Posttraumatic Stress Disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 43: 226-227. PMID 29192662 DOI: 10.1038/Npp.2017.230 |
0.295 |
|
| 2010 |
Dixon DD, Sethumadhavan D, Benneche T, Banaag AR, Tius MA, Thakur GA, Bowman A, Wood JT, Makriyannis A. Heteroadamantyl cannabinoids. Journal of Medicinal Chemistry. 53: 5656-66. PMID 20593789 DOI: 10.1021/jm100390h |
0.287 |
|
| 2020 |
Slivicki RA, Iyer V, Mali SS, Garai S, Thakur GA, Crystal JD, Hohmann AG. Positive Allosteric Modulation of CB Cannabinoid Receptor Signaling Enhances Morphine Antinociception and Attenuates Morphine Tolerance Without Enhancing Morphine- Induced Dependence or Reward. Frontiers in Molecular Neuroscience. 13: 54. PMID 32410959 DOI: 10.3389/Fnmol.2020.00054 |
0.285 |
|
| 2008 |
Sink KS, McLaughlin PJ, Wood JA, Brown C, Fan P, Vemuri VK, Peng Y, Pang Y, Olszewska T, Olzewska T, Thakur GA, Makriyannis A, Parker LA, Salamone JD. The novel cannabinoid CB1 receptor neutral antagonist AM4113 suppresses food intake and food-reinforced behavior but does not induce signs of nausea in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 946-55. PMID 17581535 DOI: 10.1038/Sj.Npp.1301476 |
0.276 |
|
| 2011 |
Rahn EJ, Thakur GA, Wood JA, Zvonok AM, Makriyannis A, Hohmann AG. Pharmacological characterization of AM1710, a putative cannabinoid CB2 agonist from the cannabilactone class: antinociception without central nervous system side-effects. Pharmacology, Biochemistry, and Behavior. 98: 493-502. PMID 21382397 DOI: 10.1016/J.Pbb.2011.02.024 |
0.269 |
|
| 2015 |
Lee WH, Xu Z, Ashpole NM, Hudmon A, Kulkarni PM, Thakur GA, Lai YY, Hohmann AG. Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics. Neuropharmacology. PMID 26071110 DOI: 10.1016/J.Neuropharm.2015.05.038 |
0.265 |
|
| 2020 |
Ben-David Y, Kagan S, Cohen Ben-Ami H, Rostami J, Mizrahi T, Kulkarni AR, Thakur GA, Vaknin-Dembinsky A, Healy LM, Brenner T, Treinin M. RIC3, the cholinergic anti-inflammatory pathway, and neuroinflammation. International Immunopharmacology. 83: 106381. PMID 32179243 DOI: 10.1016/j.intimp.2020.106381 |
0.259 |
|
| 2018 |
Quadri M, Garai S, Thakur GA, Stokes C, Gulsevin A, Horenstein NA, Papke RL. Macroscopic and microscopic activation of α7 nicotinic acetylcholine receptors by the structurally unrelated ago-PAMs B-973B and GAT107. Molecular Pharmacology. PMID 30348894 DOI: 10.1124/Mol.118.113340 |
0.258 |
|
| 2020 |
Wilkerson JL, Alberti LB, Kerwin AA, Ledent CA, Thakur GA, Makriyannis A, Milligan ED. Peripheral versus central mechanisms of the cannabinoid type 2 receptor agonist AM1710 in a mouse model of neuropathic pain. Brain and Behavior. e01850. PMID 32977358 DOI: 10.1002/brb3.1850 |
0.253 |
|
| 2008 |
Sink KS, McLaughlin PJ, Wood JAT, Brown C, Fan P, Vemuri VK, Pang Y, Olzewska T, Thakur GA, Makriyannis A, Parker LA, Salamone JD. The novel cannabinoid CB1 receptor neutral antagonist Am4113 suppresses food intake and food-reinforced behavior but does not induce signs of nausea in rats (Neuropsychopharmacology (2008) 33, (946-955) DOI: 10.1038/sj.npp.1301476) Neuropsychopharmacology. 33: 1776. DOI: 10.1038/npp.2008.49 |
0.248 |
|
| 2018 |
Kumar A, Banerjee A, Singh D, Thakur G, Kasarpalkar N, Gavali S, Gadkar S, Madan T, Mahale SD, Balasinor NH, Sachdeva G. Estradiol: A Steroid with Multiple Facets. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. PMID 29566418 DOI: 10.1055/s-0044-100920 |
0.246 |
|
| 2019 |
Stokes C, Garai S, Kulkarni AR, Cantwell LN, Noviello CM, Hibbs RE, Horenstein NA, Abboud KA, Thakur GA, Papke RL. Heteromeric neuronal nicotinic acetylcholine receptors with mutant beta subunits acquire sensitivity to α7-selective positive allosteric modulators. The Journal of Pharmacology and Experimental Therapeutics. PMID 31175218 DOI: 10.1124/Jpet.119.259499 |
0.222 |
|
| 2005 |
Thakur GA, Duclos RI, Makriyannis A. Natural cannabinoids: Templates for drug discovery Life Sciences. 78: 454-466. PMID 16242157 DOI: 10.1016/J.Lfs.2005.09.014 |
0.218 |
|
| 2018 |
Sinha K, Majhi M, Thakur G, Patidar K, Sweta J, Nayarisseri A, Singh SK. Computer aided Drug Designing for the identification of high affinity small molecule targeting CD20 for the clinical treatment of Chronic Lymphocytic Leukemia (CLL). Current Topics in Medicinal Chemistry. PMID 30526461 DOI: 10.2174/1568026619666181210150044 |
0.212 |
|
| 2012 |
Wilkerson JL, Gentry KR, Dengler EC, Wallace JA, Kerwin AA, Kuhn MN, Zvonok AM, Thakur GA, Makriyannis A, Milligan ED. Immunofluorescent spectral analysis reveals the intrathecal cannabinoid agonist, AM1241, produces spinal anti-inflammatory cytokine responses in neuropathic rats exhibiting relief from allodynia. Brain and Behavior. 2: 155-77. PMID 22574283 DOI: 10.1002/Brb3.44 |
0.211 |
|
| 2013 |
Miller RL, Thakur GA, Stewart WN, Bow JP, Bajaj S, Makriyannis A, McLaughlin PJ. Effects of a novel CB1 agonist on visual attention in male rats: role of strategy and expectancy in task accuracy. Experimental and Clinical Psychopharmacology. 21: 416-25. PMID 24099361 DOI: 10.1037/A0033668 |
0.211 |
|
| 2020 |
Onofrychuk TJ, Cai S, McElroy DL, Roebuck AJ, Greba Q, Garai S, Thakur GA, Laprairie RB, Howland JG. Effects of the cannabinoid receptor 1 positive allosteric modulator GAT211 and acute MK-801 on visual attention and impulsivity in rats assessed using the five-choice serial reaction time task. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110235. PMID 33373679 DOI: 10.1016/j.pnpbp.2020.110235 |
0.206 |
|
| 2017 |
Carey LM, Lee WH, Gutierrez T, Kulkarni PM, Thakur GA, Lai YY, Hohmann AG. Small molecule inhibitors of PSD95-nNOS protein-protein interactions suppress formalin-evoked Fos protein expression and nociceptive behavior in rats. Neuroscience. PMID 28285942 DOI: 10.1016/j.neuroscience.2017.02.055 |
0.206 |
|
| 2013 |
Thakur GA, Kulkarni AR, Deschamps JR, Papke RL. Expeditious synthesis, enantiomeric resolution, and enantiomer functional characterization of (4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (4BP-TQS): an allosteric agonist-positive allosteric modulator of α7 nicotinic acetylcholine receptors. Journal of Medicinal Chemistry. 56: 8943-7. PMID 24090443 DOI: 10.1021/jm401267t |
0.204 |
|
| 2016 |
Chopda GR, Parge VA, Thakur G, Gatley SJ, Makriyannis A, Paronis CA. Tolerance to the diuretic effects of cannabinoids and cross-tolerance to a kappa-opioid agonist in THC-treated mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 27231154 DOI: 10.1124/Jpet.116.232132 |
0.204 |
|
| 2021 |
Gauthier AG, Wu J, Lin M, Sitapara R, Kulkarni A, Thakur GA, Schmidt EE, Perron JC, Ashby CR, Mantell LL. The Positive Allosteric Modulation of alpha7-Nicotinic Cholinergic Receptors by GAT107 Increases Bacterial Lung Clearance in Hyperoxic Mice by Decreasing Oxidative Stress in Macrophages. Antioxidants (Basel, Switzerland). 10. PMID 33477969 DOI: 10.3390/antiox10010135 |
0.198 |
|
| 2021 |
Roebuck AJ, Greba Q, Smolyakova AM, Alaverdashvili M, Marks WN, Garai S, Baglot SL, Petrie G, Cain SM, Snutch TP, Thakur GA, Hill MN, Howland JG, Laprairie RB. Positive allosteric modulation of type 1 cannabinoid receptors reduces spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg. Neuropharmacology. 108553. PMID 33845076 DOI: 10.1016/j.neuropharm.2021.108553 |
0.188 |
|
| 2021 |
Nayarisseri A, Khandelwal R, Tanwar P, Madhavi M, Sharma D, Thakur G, Speck-Planche A, Singh SK. Artificial Intelligence, Big data and Machine Learning approaches in Preci-sion Medicine & Drug Discovery. Current Drug Targets. PMID 33397265 DOI: 10.2174/1389450122999210104205732 |
0.186 |
|
| 2012 |
Wilkerson JL, Gentry KR, Dengler EC, Wallace JA, Kerwin AA, Armijo LM, Kuhn MN, Thakur GA, Makriyannis A, Milligan ED. Intrathecal cannabilactone CB(2)R agonist, AM1710, controls pathological pain and restores basal cytokine levels. Pain. 153: 1091-106. PMID 22425445 DOI: 10.1016/J.Pain.2012.02.015 |
0.185 |
|
| 2016 |
Kulkarni AR, Garai S, Thakur GA. Scalable, one-pot, microwave-accelerated tandem synthesis of unsymmetrical urea derivatives. The Journal of Organic Chemistry. PMID 27966953 DOI: 10.1021/acs.joc.6b02521 |
0.183 |
|
| 2019 |
Toma W, Kyte SL, Bagdas D, Jackson A, Meade JA, Rahman F, Chen ZJ, Del Fabbro E, Cantwell L, Kulkarni A, Thakur GA, Papke RL, Bigbee JW, Gewirtz DA, Damaj MI. The α7 nicotinic receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy in mice without tolerance or altering nicotine reward and withdrawal. Experimental Neurology. 113010. PMID 31299179 DOI: 10.1016/J.Expneurol.2019.113010 |
0.181 |
|
| 2019 |
Rodrigues FC, Anil Kumar NV, Thakur G. Developments in the anticancer activity of structurally modified curcumin: An up-to-date review. European Journal of Medicinal Chemistry. 177: 76-104. PMID 31129455 DOI: 10.1016/j.ejmech.2019.04.058 |
0.175 |
|
| 2021 |
Rodrigues FC, Kumar NA, Thakur G. The Potency of Heterocyclic Curcumin Analogues: An Evidence-Based Review. Pharmacological Research. 105489. PMID 33588007 DOI: 10.1016/j.phrs.2021.105489 |
0.167 |
|
| 2018 |
Li LP, Dustrude ET, Haulcomb MM, Abreu AR, Fitz SD, Johnson PL, Thakur GA, Molosh AI, Lai Y, Shekhar A. PSD95 and nNOS interaction as a novel molecular target to modulate conditioned fear: relevance to PTSD. Translational Psychiatry. 8: 155. PMID 30108200 DOI: 10.1038/S41398-018-0208-5 |
0.166 |
|
| 2017 |
Tehri N, Kumar N, Raghu HV, Thakur G, Kumar Sharma P. Role of stereospecific nature of germinants in Bacillus megaterium spores germination. 3 Biotech. 7: 259. PMID 28744426 DOI: 10.1007/s13205-017-0897-0 |
0.153 |
|
| 2016 |
Riehle R, Pattni B, Jhaveri A, Kulkarni A, Thakur G, Degterev A, Torchilin V. Combination Nanopreparations of a Novel Proapoptotic Drug - NCL-240, TRAIL and siRNA. Pharmaceutical Research. PMID 26951567 DOI: 10.1007/S11095-016-1899-Z |
0.145 |
|
| 2021 |
Cui M, Alhamshari Y, Cantwell L, Ei-Haou S, Eptaminitaki GC, Chang M, Abou-Assali O, Tan H, Xu K, Masotti M, Plant LD, Thakur GA, Noujaim SF, Milnes J, Logothetis DE. A benzopyran with anti-arrhythmic activity is an inhibitor of Kir3.1-containing potassium channels. The Journal of Biological Chemistry. 100535. PMID 33713702 DOI: 10.1016/j.jbc.2021.100535 |
0.131 |
|
| 2020 |
Xu Y, Cantwell L, Molosh AI, Plant LD, Gazgalis D, Fitz SD, Dustrude ET, Yang Y, Kawano T, Garai S, Noujaim SF, Shekhar A, Logothetis DE, Thakur GA. The small molecule GAT1508 activates brain-specific GIRK1/2 channel heteromers and facilitates conditioned fear extinction in rodents. The Journal of Biological Chemistry. PMID 31953327 DOI: 10.1074/Jbc.Ra119.011527 |
0.13 |
|
| 2021 |
Thakur G, Kumar R, Kim SB, Lee SY, Lee SL, Rho GJ. Therapeutic Status and Available Strategies in Pancreatic Ductal Adenocarcinoma. Biomedicines. 9. PMID 33670230 DOI: 10.3390/biomedicines9020178 |
0.122 |
|
| 2016 |
Smith AE, Xu Z, Lai YY, Kulkarni PM, Thakur GA, Hohmann AG, Crystal JD. Source memory in rats is impaired by an NMDA receptor antagonist but not by PSD95-nNOS protein-protein interaction inhibitors. Behavioural Brain Research. PMID 26909849 DOI: 10.1016/J.Bbr.2016.02.021 |
0.121 |
|
| 2011 |
Patil SS, Thakur GA, Shaikh MM. Synthesis, characterization and antibacterial studies on some mixed ligand thorium complexes with N- and O-donor ligands. Acta Poloniae Pharmaceutica. 68: 881-7. PMID 22125953 |
0.116 |
|
| 2020 |
Miller DR, Khoshbouei H, Garai S, Cantwell LN, Stokes C, Thakur G, Papke RL. Allosterically Potentiated α7 Nicotinic Acetylcholine Receptors: Reduced Calcium Permeability and Current-Independent Control of Intracellular Calcium. Molecular Pharmacology. PMID 33020143 DOI: 10.1124/molpharm.120.000012 |
0.115 |
|
| 2012 |
Patil SS, Thakur GA, Shaikh MM. Synthesis, spectral, thermal and antibacterial investigations of mixed ligand complexes of thorium(IV) derived from 8-hydroxyquinoline and some amino acids. Acta Poloniae Pharmaceutica. 69: 1087-93. PMID 23285669 |
0.109 |
|
| 2006 |
Thakur GA, Shaikh MM. Synthesis, characterization, antibacterial and cytotoxicity studies on some mixed ligand Th(IV) complexes Acta Poloniae Pharmaceutica - Drug Research. 63: 95-100. PMID 17514871 |
0.107 |
|
| 2010 |
Thakur GA, Grizenko N, Sengupta SM, Schmitz N, Joober R. The 5-HTTLPR polymorphism of the serotonin transporter gene and short term behavioral response to methylphenidate in children with ADHD. Bmc Psychiatry. 10: 50. PMID 20569447 DOI: 10.1186/1471-244X-10-50 |
0.107 |
|
| 2007 |
Thakur GA, Athlekar SV, Dharwadkar SR, Shaikh MM. Synthesis and biological activity of mixed ligand dioxouranium(VI) and thorium(IV) complexes Acta Poloniae Pharmaceutica - Drug Research. 64: 9-15. PMID 17665845 |
0.106 |
|
| 2016 |
Pattni BS, Nagelli SG, Aryasomayajula B, Deshpande PP, Kulkarni A, Hartner WC, Thakur G, Degterev A, Torchilin VP. Erratum to: Targeting of Micelles and Liposomes Loaded with the Pro-Apoptotic Drug, NCL-240, into NCI/ADR-RES Cells in a 3D Spheroid Model. Pharmaceutical Research. PMID 27599990 DOI: 10.1007/S11095-016-2034-X |
0.105 |
|
| 2016 |
Pattni BS, Nagelli SG, Aryasomayajula B, Deshpande PP, Kulkarni A, Hartner WC, Thakur G, Degterev A, Torchilin VP. Targeting of Micelles and Liposomes Loaded with the Pro-Apoptotic Drug, NCL-240, into NCI/ADR-RES Cells in a 3D Spheroid Model. Pharmaceutical Research. PMID 27351426 DOI: 10.1007/s11095-016-1978-1 |
0.104 |
|
| 2009 |
Patil SS, Thakur GA, Patil VR. Synthesis, spectral and biological studies on some mixed ligand Ni(II) complexes Acta Poloniae Pharmaceutica - Drug Research. 66: 271-277. |
0.099 |
|
| 2020 |
Thakur G, Sathe G, Kundu I, Biswas B, Gautam P, Alkahtani S, Idicula-Thomas S, Sirdeshmukh R, Kishore U, Madan T. Membrane Interactome of a Recombinant Fragment of Human Surfactant Protein D Reveals GRP78 as a Novel Binding Partner in PC3, a Metastatic Prostate Cancer Cell Line. Frontiers in Immunology. 11: 600660. PMID 33542717 DOI: 10.3389/fimmu.2020.600660 |
0.098 |
|
| 1996 |
Rao PS, Thakur GA, Lahiri GK. Synthesis, characterization and redox properties of ruthenium (II) phenolato Schiff base mixed ligand complexes Indian Journal of Chemistry - Section a Inorganic, Physical, Theoretical and Analytical Chemistry. 35: 946-951. |
0.097 |
|
| 2002 |
Nikas SP, Thakur GA, Makriyannis A. A convenient and effective synthesis of 3-(3,5-dimethoxyphenyl)propanal Synthetic Communications. 32: 1751-1756. DOI: 10.1081/SCC-120004271 |
0.093 |
|
| 2007 |
Nikas SP, Thakur GA, Parrish D, Alapafuja SO, Huestis MA, Makriyannis A. A concise methodology for the synthesis of (-)-Δ9-tetrahydrocannabinol and (-)-Δ9-tetrahydrocannabivarin metabolites and their regiospecifically deuterated analogs Tetrahedron. 63: 8112-8123. DOI: 10.1016/J.Tet.2007.06.006 |
0.092 |
|
| 2021 |
Lin YT, Neumann J, Miller EF, Posner RG, Mallela A, Safta C, Ray J, Thakur G, Chinthavali S, Hlavacek WS. Daily Forecasting of Regional Epidemics of Coronavirus Disease with Bayesian Uncertainty Quantification, United States. Emerging Infectious Diseases. 27: 767-778. PMID 33622460 DOI: 10.3201/eid2703.203364 |
0.082 |
|
| 2020 |
Thakur G, Lee HJ, Jeon RH, Lee SL, Rho GJ. Small Molecule-Induced Pancreatic β-Like Cell Development: Mechanistic Approaches and Available Strategies. International Journal of Molecular Sciences. 21. PMID 32235681 DOI: 10.3390/ijms21072388 |
0.082 |
|
| 2018 |
Ha J, Xu Y, Kawano T, Hendon T, Baki L, Garai S, Papapetropoulos A, Thakur G, Plant LD, Logothetis DE. Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid PIP2. The Journal of Biological Chemistry. PMID 29317494 DOI: 10.1074/Jbc.Ra117.001679 |
0.081 |
|
| 2020 |
Lin YT, Neumann J, Miller EF, Posner RG, Mallela A, Stafa C, Ray J, Thakur G, Chinthavali S, Hlavacek WS. Daily Forecasting of New Cases for Regional Epidemics of Coronavirus Disease 2019 with Bayesian Uncertainty Quantification. Medrxiv : the Preprint Server For Health Sciences. PMID 32743595 DOI: 10.1101/2020.07.20.20151506 |
0.08 |
|
| 2020 |
Lin YT, Neumann J, Miller E, Posner RG, Mallela A, Safta C, Ray J, Thakur G, Chinthavali S, Hlavacek WS. Daily Forecasting of New Cases for Regional Epidemics of Coronavirus Disease 2019 with Bayesian Uncertainty Quantification. Arxiv. PMID 32743021 |
0.08 |
|
| 2019 |
Pan J, Palmerston Mendes L, Yao M, Filipczak N, Garai S, Thakur GA, Sarisozen C, Torchilin VP. Polyamidoamine dendrimers-based nanomedicine for combination therapy with siRNA and chemotherapeutics to overcome multidrug resistance. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 30633973 DOI: 10.1016/J.Ejpb.2019.01.006 |
0.077 |
|
| 2018 |
Thakur G, Rodrigues FC, Singh K. Crosslinking Biopolymers for Advanced Drug Delivery and Tissue Engineering Applications. Advances in Experimental Medicine and Biology. 1078: 213-231. PMID 30357625 DOI: 10.1007/978-981-13-0950-2_11 |
0.076 |
|
| 2017 |
Jiang K, Wang Y, Thakur G, Kotsuchibashi Y, Naicker S, Narain R, Thundat T. Rapid and Highly Sensitive Detection of Dopamine using Conjugated Oxaborole based Polymer and Glycopolymer Systems. Acs Applied Materials & Interfaces. PMID 28437064 DOI: 10.1021/Acsami.7B04178 |
0.076 |
|
| 2009 |
Thakur GA, Joober R, Brunet A. Development and persistence of posttraumatic stress disorder and the 5-HTTLPR polymorphism. Journal of Traumatic Stress. 22: 240-3. PMID 19444877 DOI: 10.1002/Jts.20405 |
0.068 |
|
| 2020 |
Hebbi V, Thakur G, Rathore AS. Process analytical technology application for protein PEGylation using near infrared spectroscopy: G-CSF as a case study. Journal of Biotechnology. PMID 33039551 DOI: 10.1016/j.jbiotec.2020.10.006 |
0.066 |
|
| 2015 |
Thakur G, Singh A, Singh I. Chitosan-Montmorillonite Polymer Composites: Formulation and Evaluation of Sustained Release Tablets of Aceclofenac. Scientia Pharmaceutica. 84: 603-617. PMID 28656939 DOI: 10.3390/scipharm84040603 |
0.066 |
|
| 2019 |
Thakur G, Prakash G, Murthy V, Sable N, Menon S, Alrokayan SH, Khan HA, Murugaiah V, Bakshi G, Kishore U, Madan T. Human SP-D Acts as an Innate Immune Surveillance Molecule Against Androgen-Responsive and Androgen-Resistant Prostate Cancer Cells. Frontiers in Oncology. 9: 565. PMID 31355132 DOI: 10.3389/Fonc.2019.00565 |
0.066 |
|
| 2019 |
Pandit H, Kale K, Yamamoto H, Thakur G, Rokade S, Chakraborty P, Vasudevan M, Kishore U, Madan T, Fichorova RN. Surfactant Protein D Reverses the Gene Signature of Transepithelial HIV-1 Passage and Restricts the Viral Transfer Across the Vaginal Barrier. Frontiers in Immunology. 10: 264. PMID 30984160 DOI: 10.3389/Fimmu.2019.00264 |
0.066 |
|
| 2012 |
Sengupta SM, Grizenko N, Thakur GA, Bellingham J, DeGuzman R, Robinson S, TerStepanian M, Poloskia A, Shaheen SM, Fortier ME, Choudhry Z, Joober R. Differential association between the norepinephrine transporter gene and ADHD: role of sex and subtype. Journal of Psychiatry & Neuroscience : Jpn. 37: 129-37. PMID 22297068 DOI: 10.1503/jpn.110073 |
0.062 |
|
| 2013 |
Anderson-Schmidt H, Beltcheva O, Brandon MD, Byrne EM, Diehl EJ, Duncan L, Gonzalez SD, Hannon E, Kantojärvi K, Karagiannidis I, Kos MZ, Kotyuk E, Laufer BI, Mantha K, McGregor NW, ... ... Thakur GA, et al. Selected rapporteur summaries from the XX World Congress of Psychiatric Genetics, Hamburg, Germany, October 14-18, 2012. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 162: 96-121. PMID 23341144 DOI: 10.1002/Ajmg.B.32132 |
0.057 |
|
| 1996 |
Santra BK, Thakur GA, Ghosh P, Pramanik A, Lahiri GK. A Novel Example of Metal-Mediated Aromatic Thiolation in a Ruthenium Complex. Crystal Structure of RuII(SC6H4N=NC6H4N) 2 Inorganic Chemistry. 35: 3050-3052. DOI: 10.1021/Ic950810P |
0.056 |
|
| 2012 |
Choudhry Z, Sengupta SM, Grizenko N, Fortier ME, Thakur GA, Bellingham J, Joober R. LPHN3 and attention-deficit/hyperactivity disorder: interaction with maternal stress during pregnancy. Journal of Child Psychology and Psychiatry, and Allied Disciplines. 53: 892-902. PMID 22486528 DOI: 10.1111/j.1469-7610.2012.02551.x |
0.056 |
|
| 2013 |
Choudhry Z, Sengupta SM, Grizenko N, Thakur GA, Fortier ME, Schmitz N, Joober R. Association between obesity-related gene FTO and ADHD. Obesity (Silver Spring, Md.). 21: E738-44. PMID 23512716 DOI: 10.1002/oby.20444 |
0.054 |
|
| 2017 |
Thakur G, Prashanthi K, Jiang K, Thundat T. Self-Assembly of Human Serum Albumin: A Simplex Phenomenon. Biomolecules. 7. PMID 28930179 DOI: 10.3390/biom7030069 |
0.051 |
|
| 2018 |
Hebbi V, Thakur G, Rathore AS. Process Analytical Technology Implementation for Protein Refolding: GCSF as a Case Study. Biotechnology and Bioengineering. PMID 30552665 DOI: 10.1002/bit.26900 |
0.05 |
|
| 2002 |
Nikas SP, Thakur GA, Makriyannis A. Synthesis of side chain specifically deuterated (-)-Δ9-tetrahydrocannabinols Journal of Labelled Compounds and Radiopharmaceuticals. 45: 1065-1076. DOI: 10.1002/Jlcr.626 |
0.05 |
|
| 1999 |
Meyers PM, Thakur GA, Tomsick TA. Temporary endovascular balloon occlusion of the internal carotid artery with a nondetachable silicone balloon catheter: Analysis of technique and cost American Journal of Neuroradiology. 20: 559-564. PMID 10319959 |
0.05 |
|
| 2021 |
Thakur G, Hebbi V, Rathore AS. Near Infrared Spectroscopy as a PAT Tool for Monitoring and Control of Protein and Excipient Concentration in Ultrafiltration of Highly Concentrated Antibody Formulations. International Journal of Pharmaceutics. 120456. PMID 33711473 DOI: 10.1016/j.ijpharm.2021.120456 |
0.05 |
|
| 2021 |
Thakur G, Ghumade P, Rathore AS. Process analytical technology in continuous processing: Model-based real time control of pH between capture chromatography and viral inactivation for monoclonal antibody production. Journal of Chromatography. A. 1658: 462614. PMID 34656843 DOI: 10.1016/j.chroma.2021.462614 |
0.049 |
|
| 2002 |
Nikas SP, Thakur GA, Makriyannis A. Regiospecifically deuterated (-)-Δ9-tetrahydrocannabivarins Journal of the Chemical Society. Perkin Transactions 1. 2544-2548. |
0.045 |
|
| 2020 |
Kamdar HA, Hamed M, Smetana KS, Shanmugam K, Peters E, Yasin R, Thakur G, Gopal M, Sawalha K, Greene-Chandos D, Hussein O. Lorazepam timing for acute convulsive seizure control (LoTASC). Seizure. 83: 41-47. PMID 33080484 DOI: 10.1016/j.seizure.2020.09.024 |
0.045 |
|
| 1996 |
Thakur GA, Narayanaswamy K, Lahiri GK. Synthesis, characterization and redox properties of ruthenium(II) dithiocarbonato complexes having 2,2′-bipyridine coligands Indian Journal of Chemistry - Section a Inorganic, Physical, Theoretical and Analytical Chemistry. 35: 379-384. |
0.044 |
|
| 2015 |
Sengupta SM, Fortier MÈ, Thakur GA, Bhat V, Grizenko N, Joober R. Parental psychopathology in families of children with attention-deficit/hyperactivity disorder and exposed to maternal smoking during pregnancy. Journal of Child Psychology and Psychiatry, and Allied Disciplines. 56: 122-9. PMID 24961295 DOI: 10.1111/jcpp.12286 |
0.038 |
|
| 2020 |
Singh J, Thakur G, Alexander J, Rayi A, Peng J, Bell W, Britton J. Predictors of Nonconvulsive Seizure and Their Effect on Short-term Outcome. Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society. PMID 32141985 DOI: 10.1097/WNP.0000000000000687 |
0.037 |
|
| 2019 |
Thakur G, Hebbi V, Rathore AS. An NIR based PAT approach for real-time control of loading in Protein A chromatography in continuous manufacturing of monoclonal antibodies. Biotechnology and Bioengineering. PMID 31788777 DOI: 10.1002/bit.27236 |
0.033 |
|
| 2013 |
Thakur GA, Sengupta SM, Grizenko N, Schmitz N, Pagé V, Joober R. Maternal smoking during pregnancy and ADHD: a comprehensive clinical and neurocognitive characterization. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 15: 149-57. PMID 22529219 DOI: 10.1093/ntr/nts102 |
0.03 |
|
| 2020 |
Lee VH, Thakur G, Nimjee SM, Youssef PP, Lakhani S, Heaton S, Powers CJ. Early neurologic decline in acute ischemic stroke patients receiving thrombolysis with large vessel occlusion and mild deficits. Journal of Neurointerventional Surgery. PMID 32277039 DOI: 10.1136/Neurintsurg-2020-015871 |
0.029 |
|
| 2020 |
Thakur G, Hebbi V, Parida S, Rathore AS. Automation of Dead End Filtration: An Enabler for Continuous Processing of Biotherapeutics. Frontiers in Bioengineering and Biotechnology. 8: 758. PMID 32719791 DOI: 10.3389/fbioe.2020.00758 |
0.029 |
|
| 2012 |
Thakur GA, Sengupta SM, Grizenko N, Choudhry Z, Joober R. Family-based association study of ADHD and genes increasing the risk for smoking behaviours. Archives of Disease in Childhood. 97: 1027-33. PMID 23109089 DOI: 10.1136/archdischild-2012-301882 |
0.025 |
|
| 2013 |
Kulkarni AR, Thakur GA. Microwave-assisted expeditious and efficient synthesis of cyclopentene ring-fused tetrahydroquinoline derivatives using three-component Povarov reaction Tetrahedron Letters. 54: 6592-6595. DOI: 10.1016/j.tetlet.2013.09.107 |
0.024 |
|
| 2021 |
Thakur G, Saxena N, Tiwari A, Rathore AS. Control of Surge Tanks for Continuous Manufacturing of Monoclonal Antibodies. Biotechnology and Bioengineering. PMID 33547800 DOI: 10.1002/bit.27706 |
0.024 |
|
| 2016 |
Thakur G, Singh A, Singh I. Formulation and evaluation of transdermal composite films of chitosan-montmorillonite for the delivery of curcumin. International Journal of Pharmaceutical Investigation. 6: 23-31. PMID 27014616 DOI: 10.4103/2230-973X.176468 |
0.02 |
|
| 2012 |
Thakur GA, Sengupta SM, Grizenko N, Choudhry Z, Joober R. Comprehensive phenotype/genotype analyses of the norepinephrine transporter gene (SLC6A2) in ADHD: relation to maternal smoking during pregnancy. Plos One. 7: e49616. PMID 23185385 DOI: 10.1371/journal.pone.0049616 |
0.017 |
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| 2021 |
Kateja N, Tiwari A, Thakur G, Rathore AS. Complete or periodic continuity in continuous manufacturing platforms for production of monoclonal antibodies? Biotechnology Journal. e2000524. PMID 33773062 DOI: 10.1002/biot.202000524 |
0.016 |
|
| 2021 |
Thakur G, Thakur S, Thakur H. Status and challenges for tuberculosis control in India - Stakeholders' perspective. The Indian Journal of Tuberculosis. 68: 334-339. PMID 34099198 DOI: 10.1016/j.ijtb.2020.10.001 |
0.011 |
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