Stuart C. Sealfon - Publications

Affiliations: 
Program in Computational Biology New York University, New York, NY, United States 
Area:
Cell Biology, Immunology, Molecular Biology

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Year Citation  Score
2020 Ruf-Zamojski FM, Zamojski MA, Nudelman G, Ge Y, Mendelev N, Smith GR, Zhou X, Toufaily C, Schang G, Gambino LO, Liu H, Gomez Castanon RG, Moriwaki M, Nair V, Pincas H, ... ... Sealfon SC, et al. SAT-298 Integrative Single-Cell Transcriptomic and Epigenomic Landscape of Mouse Anterior Pituitary Cell Types Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.593  0.354
2019 Monteagudo PL, Muñoz-Moreno R, Fribourg M, Potla U, Mena I, Marjanovic N, Hartmann BM, Sealfon SC, García-Sastre A, Ramos I, Fernández-Sesma A. Differential modulation of innate immune responses in human primary cells by influenza A viruses carrying human or avian non-structural 1 proteins. Journal of Virology. PMID 31597767 DOI: 10.1128/Jvi.00999-19  0.318
2019 Ramos I, Smith G, Ruf-Zamojski F, Martinez-Romero C, Fribourg M, Carbajal EA, Hartmann BM, Nair VD, Marjanovic N, Monteagudo PL, DeJesus VA, Mutetwa T, Zamojski M, Tan GS, Jayaprakash C, ... ... Sealfon SC, et al. Innate immune response to influenza virus at single-cell resolution in human epithelial cells revealed paracrine induction of interferon lambda 1. Journal of Virology. PMID 31375585 DOI: 10.1128/Jvi.00559-19  0.329
2019 Mao W, Zaslavsky E, Hartmann BM, Sealfon SC, Chikina M. Pathway-level information extractor (PLIER) for gene expression data. Nature Methods. 16: 607-610. PMID 31249421 DOI: 10.1038/S41592-019-0456-1  0.336
2019 Ruf-Zamojski F, Ge Y, Pincas H, Shan J, Song Y, Hines N, Kelley K, Montagna C, Nair P, Toufaily C, Bernard DJ, Mellon PL, Nair V, Turgeon JL, Sealfon SC. Cytogenetic, Genomic, and Functional Characterization of Pituitary Gonadotrope Cell Lines. Journal of the Endocrine Society. 3: 902-920. PMID 31020055 DOI: 10.1210/Js.2019-00064  0.306
2018 Ruf-Zamojski F, Ge Y, Nair V, Zamojski M, Pincas H, Toufaily C, Tome-Garcia J, Stoeckius M, Stephenson W, Smith GR, Bernard DJ, Tsankova NM, Hartmann BM, Fribourg M, Smibert P, ... ... Sealfon SC, et al. Single-cell stabilization method identifies gonadotrope transcriptional dynamics and pituitary cell type heterogeneity. Nucleic Acids Research. PMID 30357357 DOI: 10.1093/Nar/Gky991  0.37
2018 Ruf-Zamojski F, Fribourg M, Ge Y, Nair V, Pincas H, Zaslavsky E, Nudelman G, Tuminello SJ, Watanabe H, Turgeon JL, Sealfon SC. Regulatory Architecture of the LβT2 Gonadotrope Cell Underlying the Response to Gonadotropin-Releasing Hormone. Frontiers in Endocrinology. 9: 34. PMID 29487567 DOI: 10.3389/Fendo.2018.00034  0.366
2017 Stern E, Ruf-Zamojski F, Zalepa-King L, Pincas H, Choi SG, Peskin CS, Fernand H, Turgeon JL, Sealfon SC. Modeling and High-Throughput Experimental Data Uncover the Mechanisms Underlying Fshb Gene Sensitivity to Gonadotropin-Releasing Hormone Pulse Frequency. The Journal of Biological Chemistry. PMID 28385888 DOI: 10.1074/Jbc.M117.783886  0.321
2016 Choi SG, Wang Q, Jia J, Chikina M, Pincas H, Dolios G, Sasaki K, Wang R, Minamino N, Salton SR, Sealfon SC. Characterization of gonadotrope secretoproteome identifies neurosecretory protein VGF-derived peptide suppression of follicle-stimulating hormone gene expression. The Journal of Biological Chemistry. PMID 27466366 DOI: 10.1074/Jbc.M116.740365  0.368
2016 Nogusa S, Thapa RJ, Dillon CP, Liedmann S, Oguin TH, Ingram JP, Rodriguez DA, Kosoff R, Sharma S, Sturm O, Verbist K, Gough PJ, Bertin J, Hartmann BM, Sealfon SC, et al. RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus. Cell Host & Microbe. PMID 27321907 DOI: 10.1016/J.Chom.2016.05.011  0.329
2016 Baki L, Fribourg M, Younkin J, Eltit JM, Moreno JL, Park G, Vysotskaya Z, Narahari A, Sealfon SC, Gonzalez-Maeso J, Logothetis DE. Cross-signaling in metabotropic glutamate 2 and serotonin 2A receptor heteromers in mammalian cells. Pflugers Archiv : European Journal of Physiology. PMID 26780666 DOI: 10.1007/S00424-015-1780-7  0.386
2015 Thakar J, Hartmann BM, Marjanovic N, Sealfon SC, Kleinstein SH. Comparative analysis of anti-viral transcriptomics reveals novel effects of influenza immune antagonism. Bmc Immunology. 16: 46. PMID 26272204 DOI: 10.1186/S12865-015-0107-Y  0.317
2015 Patil S, Fribourg M, Ge Y, Batish M, Tyagi S, Hayot F, Sealfon SC. Single-cell analysis shows that paracrine signaling by first responder cells shapes the interferon-β response to viral infection. Science Signaling. 8: ra16. PMID 25670204 DOI: 10.1126/Scisignal.2005728  0.371
2015 Chikina M, Zaslavsky E, Sealfon SC. CellCODE: a robust latent variable approach to differential expression analysis for heterogeneous cell populations. Bioinformatics (Oxford, England). 31: 1584-91. PMID 25583121 DOI: 10.1093/Bioinformatics/Btv015  0.318
2014 Choi SG, Wang Q, Jia J, Pincas H, Turgeon JL, Sealfon SC. Growth differentiation factor 9 (GDF9) forms an incoherent feed-forward loop modulating follicle-stimulating hormone β-subunit (FSHβ) gene expression. The Journal of Biological Chemistry. 289: 16164-75. PMID 24778184 DOI: 10.1074/Jbc.M113.537696  0.378
2014 Hartmann BM, Marjanovic N, Nudelman G, Moran TM, Sealfon SC. Combinatorial cytokine code generates anti-viral state in dendritic cells. Frontiers in Immunology. 5: 73. PMID 24616721 DOI: 10.3389/Fimmu.2014.00073  0.346
2014 Wang Q, Chikina MD, Pincas H, Sealfon SC. Homer1 alternative splicing is regulated by gonadotropin-releasing hormone and modulates gonadotropin gene expression. Molecular and Cellular Biology. 34: 1747-56. PMID 24591653 DOI: 10.1128/Mcb.01401-13  0.361
2014 Pincas H, Choi SG, Wang Q, Jia J, Turgeon JL, Sealfon SC. Outside the box signaling: secreted factors modulate GnRH receptor-mediated gonadotropin regulation. Molecular and Cellular Endocrinology. 385: 56-61. PMID 23994024 DOI: 10.1016/J.Mce.2013.08.015  0.41
2013 Tabbaa OP, Nudelman G, Sealfon SC, Hayot F, Jayaprakash C. Noise propagation through extracellular signaling leads to fluctuations in gene expression. Bmc Systems Biology. 7: 94. PMID 24067165 DOI: 10.1186/1752-0509-7-94  0.367
2013 Moreno JL, Holloway T, Rayannavar V, Sealfon SC, González-Maeso J. Chronic treatment with LY341495 decreases 5-HT(2A) receptor binding and hallucinogenic effects of LSD in mice. Neuroscience Letters. 536: 69-73. PMID 23333599 DOI: 10.1016/J.Neulet.2012.12.053  0.314
2013 Braun DA, Fribourg M, Sealfon SC. Cytokine response is determined by duration of receptor and signal transducers and activators of transcription 3 (STAT3) activation. The Journal of Biological Chemistry. 288: 2986-93. PMID 23166328 DOI: 10.1074/Jbc.M112.386573  0.521
2013 Baki L, Eltit JM, Fribourg M, Younkin J, Park G, Vysotskaya Z, Sealfon SC, Liapakis G, Gonzalez-Maeso J, Logothetis DE. Functional Crosstalk between mGluR2 and 5-HT2A Depends on their Expression Ratios Biophysical Journal. 104: 116a. DOI: 10.1016/J.Bpj.2012.11.671  0.389
2013 Tabbaa OP, Nudelman G, Sealfon SC, Jayaprakash C. Noise Propagation through Cytokine Signaling Leads to Fluctuations in Interferon-Induced Genes Biophysical Journal. 104: 493a. DOI: 10.1016/J.Bpj.2012.11.2719  0.363
2012 Moreno JL, Muguruza C, Umali A, Mortillo S, Holloway T, Pilar-Cuéllar F, Mocci G, Seto J, Callado LF, Neve RL, Milligan G, Sealfon SC, López-Giménez JF, Meana JJ, Benson DL, et al. Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A·mGlu2) receptor heteromerization and its psychoactive behavioral function. The Journal of Biological Chemistry. 287: 44301-19. PMID 23129762 DOI: 10.1074/Jbc.M112.413161  0.331
2012 Nair VD, Ge Y, Balasubramaniyan N, Kim J, Okawa Y, Chikina M, Troyanskaya O, Sealfon SC. Involvement of histone demethylase LSD1 in short-time-scale gene expression changes during cell cycle progression in embryonic stem cells. Molecular and Cellular Biology. 32: 4861-76. PMID 23028048 DOI: 10.1128/Mcb.00816-12  0.333
2012 González-Maeso J, Sealfon SC. Functional selectivity in GPCR heterocomplexes. Mini Reviews in Medicinal Chemistry. 12: 851-5. PMID 22681249 DOI: 10.2174/138955712800959152  0.349
2012 Choi SG, Jia J, Pfeffer RL, Sealfon SC. G proteins and autocrine signaling differentially regulate gonadotropin subunit expression in pituitary gonadotrope. The Journal of Biological Chemistry. 287: 21550-60. PMID 22549790 DOI: 10.1074/Jbc.M112.348607  0.368
2012 Yuen T, Choi SG, Pincas H, Waring DW, Sealfon SC, Turgeon JL. Optimized amplification and single-cell analysis identify GnRH-mediated activation of Rap1b in primary rat gonadotropes. Molecular and Cellular Endocrinology. 350: 10-9. PMID 22127306 DOI: 10.1016/J.Mce.2011.11.017  0.379
2011 Shimoni Y, Nudelman G, Hayot F, Sealfon SC. Multi-scale stochastic simulation of diffusion-coupled agents and its application to cell culture simulation. Plos One. 6: e29298. PMID 22216238 DOI: 10.1371/Journal.Pone.0029298  0.301
2011 Fribourg M, Moreno JL, Holloway T, Provasi D, Baki L, Mahajan R, Park G, Adney SK, Hatcher C, Eltit JM, Ruta JD, Albizu L, Li Z, Umali A, Shim J, ... ... Sealfon SC, et al. Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs. Cell. 147: 1011-23. PMID 22118459 DOI: 10.1016/J.Cell.2011.09.055  0.325
2011 Bowles R, Patil S, Pincas H, Sealfon SC. Optimized protocol for efficient transfection of dendritic cells without cell maturation. Journal of Visualized Experiments : Jove. e2766. PMID 21775957 DOI: 10.3791/2766  0.342
2011 Choi SG, Ruf-Zamojski F, Pincas H, Roysam B, Sealfon SC. Characterization of a MAPK scaffolding protein logic gate in gonadotropes. Molecular Endocrinology (Baltimore, Md.). 25: 1027-39. PMID 21436256 DOI: 10.1210/Me.2010-0387  0.364
2011 Hu J, Nudelman G, Shimoni Y, Kumar M, Ding Y, López C, Hayot F, Wetmur JG, Sealfon SC. Role of cell-to-cell variability in activating a positive feedback antiviral response in human dendritic cells. Plos One. 6: e16614. PMID 21347441 DOI: 10.1371/Journal.Pone.0016614  0.365
2011 Moreno JL, Holloway T, Albizu L, Sealfon SC, González-Maeso J. Metabotropic glutamate mGlu2 receptor is necessary for the pharmacological and behavioral effects induced by hallucinogenic 5-HT2A receptor agonists. Neuroscience Letters. 493: 76-9. PMID 21276828 DOI: 10.1016/J.Neulet.2011.01.046  0.322
2011 Sealfon SC. Synthesis, Internalization, Recycling, and Regulation of Peptide Hormone Receptors Comprehensive Physiology. 23-38. DOI: 10.1002/Cphy.Cp070102  0.341
2010 Patil S, Pincas H, Seto J, Nudelman G, Nudelman I, Sealfon SC. Signaling network of dendritic cells in response to pathogens: a community-input supported knowledgebase. Bmc Systems Biology. 4: 137. PMID 20929569 DOI: 10.1186/1752-0509-4-137  0.316
2010 Bowles R, Patil S, Pincas H, Sealfon SC. Validation of efficient high-throughput plasmid and siRNA transfection of human monocyte-derived dendritic cells without cell maturation. Journal of Immunological Methods. 363: 21-8. PMID 20875421 DOI: 10.1016/J.Jim.2010.09.028  0.355
2010 Seto J, Qiao L, Guenzel CA, Xiao S, Shaw ML, Hayot F, Sealfon SC. Novel Nipah virus immune-antagonism strategy revealed by experimental and computational study. Journal of Virology. 84: 10965-73. PMID 20739535 DOI: 10.1128/Jvi.01335-10  0.32
2010 Albizu L, Moreno JL, González-Maeso J, Sealfon SC. Heteromerization of G protein-coupled receptors: relevance to neurological disorders and neurotherapeutics. Cns & Neurological Disorders Drug Targets. 9: 636-50. PMID 20632964 DOI: 10.2174/187152710793361586  0.352
2010 Fink MY, Pincas H, Choi SG, Nudelman G, Sealfon SC. Research resource: Gonadotropin-releasing hormone receptor-mediated signaling network in LbetaT2 cells: a pathway-based web-accessible knowledgebase. Molecular Endocrinology (Baltimore, Md.). 24: 1863-71. PMID 20592162 DOI: 10.1210/Me.2009-0530  0.375
2010 Shimoni Y, Fink MY, Choi SG, Sealfon SC. Plato's cave algorithm: inferring functional signaling networks from early gene expression shadows. Plos Computational Biology. 6: e1000828. PMID 20585619 DOI: 10.1371/Journal.Pcbi.1000828  0.313
2010 Nudelman G, Ge Y, Hu J, Kumar M, Seto J, Duke JL, Kleinstein SH, Hayot F, Sealfon SC, Wetmur JG. Coregulation mapping based on individual phenotypic variation in response to virus infection. Immunome Research. 6: 2. PMID 20298589 DOI: 10.1186/1745-7580-6-2  0.303
2010 Zaslavsky E, Hershberg U, Seto J, Pham AM, Marquez S, Duke JL, Wetmur JG, Tenoever BR, Sealfon SC, Kleinstein SH. Antiviral response dictated by choreographed cascade of transcription factors. Journal of Immunology (Baltimore, Md. : 1950). 184: 2908-17. PMID 20164420 DOI: 10.4049/Jimmunol.0903453  0.347
2010 Qiao L, Phipps-Yonas H, Hartmann B, Moran TM, Sealfon SC, Hayot F. Immune response modeling of interferon beta-pretreated influenza virus-infected human dendritic cells. Biophysical Journal. 98: 505-14. PMID 20159146 DOI: 10.1016/J.Bpj.2009.10.049  0.323
2009 Hu J, Iyer-Biswas S, Sealfon SC, Wetmur J, Jayaprakash C, Hayot F. Power-laws in interferon-B mRNA distribution in virus-infected dendritic cells. Biophysical Journal. 97: 1984-9. PMID 19804729 DOI: 10.1016/J.Bpj.2009.05.067  0.347
2009 González-Maeso J, Sealfon SC. Agonist-trafficking and hallucinogens. Current Medicinal Chemistry. 16: 1017-27. PMID 19275609 DOI: 10.2174/092986709787581851  0.371
2009 Biswas SI, Hayot F, Jayaprakash C, Hu J, Wetmur J, Sealfon S. A Powerful Response to Viral Infection Biophysical Journal. 96: 567a. DOI: 10.1016/J.Bpj.2008.12.3718  0.317
2009 Fribourg-Casajuana M, González-Maeso J, Sealfon SC, Logothetis DE. Functional Evidence for Gi-Gq crosstalk through G protein-coupled Receptor Heterocomplexes Biophysical Journal. 96: 674a-675a. DOI: 10.1016/J.Bpj.2008.12.3565  0.382
2008 Phipps-Yonas H, Seto J, Sealfon SC, Moran TM, Fernandez-Sesma A. Interferon-beta pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus. Plos Pathogens. 4: e1000193. PMID 18974865 DOI: 10.1371/Journal.Ppat.1000193  0.303
2008 Phipps-Yonas H, Jiang K, Hartmann BM, Ge Y, Sealfon SC, Moran TM. A comprehensive evaluation of human plasmacytoid dendritic cells using small volumes of human blood. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 28: 501-7. PMID 18729740 DOI: 10.1089/Jir.2008.0014  0.308
2008 Sealfon SC, González-Maeso J. Receptor pair for schizophrenia. Pediatric Research. 64: 1. PMID 18574404 DOI: 10.1203/Pdr.0B013E318180052A  0.325
2008 Berezhkovskii AM, Coppey M, Sealfon SC, Shvartsman S. Cell-to-cell communication: time and length scales of ligand internalization in cultures of suspended cells. The Journal of Chemical Physics. 128: 225102. PMID 18554059 DOI: 10.1063/1.2936845  0.324
2008 Viswanathan GA, Seto J, Patil S, Nudelman G, Sealfon SC. Getting started in biological pathway construction and analysis. Plos Computational Biology. 4: e16. PMID 18463709 DOI: 10.1371/Journal.Pcbi.0040016  0.308
2008 Arsov I, Li X, Matthews G, Coradin J, Hartmann B, Simon AK, Sealfon SC, Yue Z. BAC-mediated transgenic expression of fluorescent autophagic protein Beclin 1 reveals a role for Beclin 1 in lymphocyte development. Cell Death and Differentiation. 15: 1385-95. PMID 18451870 DOI: 10.1038/Cdd.2008.59  0.306
2008 González-Maeso J, Ang RL, Yuen T, Chan P, Weisstaub NV, López-Giménez JF, Zhou M, Okawa Y, Callado LF, Milligan G, Gingrich JA, Filizola M, Meana JJ, Sealfon SC. Identification of a serotonin/glutamate receptor complex implicated in psychosis. Nature. 452: 93-7. PMID 18297054 DOI: 10.1038/Nature06612  0.313
2007 Ruf F, Hayot F, Park MJ, Ge Y, Lin G, Roysam B, Sealfon SC. Noise propagation and scaling in regulation of gonadotrope biosynthesis. Biophysical Journal. 93: 4474-80. PMID 17720728 DOI: 10.1529/Biophysj.107.115170  0.662
2007 Hu J, Sealfon SC, Hayot F, Jayaprakash C, Kumar M, Pendleton AC, Ganee A, Fernandez-Sesma A, Moran TM, Wetmur JG. Chromosome-specific and noisy IFNB1 transcription in individual virus-infected human primary dendritic cells. Nucleic Acids Research. 35: 5232-41. PMID 17675303 DOI: 10.1093/Nar/Gkm557  0.332
2007 Lee KB, Khivansara V, Santos MM, Lamba P, Yuen T, Sealfon SC, Bernard DJ. Bone morphogenetic protein 2 and activin A synergistically stimulate follicle-stimulating hormone beta subunit transcription. Journal of Molecular Endocrinology. 38: 315-30. PMID 17293449 DOI: 10.1677/Jme.1.02196  0.398
2007 González-Maeso J, Weisstaub NV, Zhou M, Chan P, Ivic L, Ang R, Lira A, Bradley-Moore M, Ge Y, Zhou Q, Sealfon SC, Gingrich JA. Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior. Neuron. 53: 439-52. PMID 17270739 DOI: 10.1016/J.Neuron.2007.01.008  0.343
2006 Ruf F, Park MJ, Hayot F, Lin G, Roysam B, Ge Y, Sealfon SC. Mixed analog/digital gonadotrope biosynthetic response to gonadotropin-releasing hormone. The Journal of Biological Chemistry. 281: 30967-78. PMID 16916798 DOI: 10.1074/Jbc.M606486200  0.656
2006 Grisotto MG, Garin A, Martin AP, Jensen KK, Chan P, Sealfon SC, Lira SA. The human herpesvirus 8 chemokine receptor vGPCR triggers autonomous proliferation of endothelial cells. The Journal of Clinical Investigation. 116: 1264-73. PMID 16604194 DOI: 10.1172/Jci26666  0.355
2005 Xie J, Bliss SP, Nett TM, Ebersole BJ, Sealfon SC, Roberson MS. Transcript profiling of immediate early genes reveals a unique role for activating transcription factor 3 in mediating activation of the glycoprotein hormone alpha-subunit promoter by gonadotropin-releasing hormone. Molecular Endocrinology (Baltimore, Md.). 19: 2624-38. PMID 15961508 DOI: 10.1210/Me.2005-0056  0.36
2005 Sealfon SC. Teaching resources. G-protein-coupled receptors. Science's Stke : Signal Transduction Knowledge Environment. 2005: tr11. PMID 15827322 DOI: 10.1126/Stke.2792005Tr11  0.326
2005 Omari KM, John GR, Sealfon SC, Raine CS. CXC chemokine receptors on human oligodendrocytes: implications for multiple sclerosis. Brain : a Journal of Neurology. 128: 1003-15. PMID 15774504 DOI: 10.1093/Brain/Awh479  0.311
2004 Ruf F, Sealfon SC. Genomics view of gonadotrope signaling circuits. Trends in Endocrinology and Metabolism: Tem. 15: 331-8. PMID 15350605 DOI: 10.1016/J.Tem.2004.07.008  0.373
2004 Mobbs CV, Yen K, Mastaitis J, Nguyen H, Watson E, Wurmbach E, Sealfon SC, Brooks A, Salton SR. Mining microarrays for metabolic meaning: nutritional regulation of hypothalamic gene expression. Neurochemical Research. 29: 1093-103. PMID 15176466 DOI: 10.1023/B:Nere.0000023596.49140.E0  0.315
2003 Ruf F, Fink MY, Sealfon SC. Structure of the GnRH receptor-stimulated signaling network: insights from genomics. Frontiers in Neuroendocrinology. 24: 181-99. PMID 14596811 DOI: 10.1016/S0091-3022(03)00027-X  0.373
2003 Nair VD, Sealfon SC. Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor. The Journal of Biological Chemistry. 278: 47053-61. PMID 12970364 DOI: 10.1074/Jbc.M303364200  0.341
2003 Nair VD, Olanow CW, Sealfon SC. Activation of phosphoinositide 3-kinase by D2 receptor prevents apoptosis in dopaminergic cell lines. The Biochemical Journal. 373: 25-32. PMID 12683952 DOI: 10.1042/Bj20030017  0.376
2003 Ebersole BJ, Visiers I, Weinstein H, Sealfon SC. Molecular basis of partial agonism: orientation of indoleamine ligands in the binding pocket of the human serotonin 5-HT2A receptor determines relative efficacy. Molecular Pharmacology. 63: 36-43. PMID 12488534 DOI: 10.1124/Mol.63.1.36  0.336
2003 González-Maeso J, Yuen T, Ebersole BJ, Wurmbach E, Lira A, Zhou M, Weisstaub N, Hen R, Gingrich JA, Sealfon SC. Transcriptome Fingerprints Distinguish Hallucinogenic and Nonhallucinogenic 5-Hydroxytryptamine 2A Receptor Agonist Effects in Mouse Somatosensory Cortex The Journal of Neuroscience. 23: 8836-8843. DOI: 10.1523/Jneurosci.23-26-08836.2003  0.393
2002 Wurmbach E, González-Maeso J, Yuen T, Ebersole BJ, Mastaitis JW, Mobbs CV, Sealfon SC. Validated genomic approach to study differentially expressed genes in complex tissues. Neurochemical Research. 27: 1027-33. PMID 12462402 DOI: 10.1023/A:1020900720328  0.347
2002 Prioleau C, Visiers I, Ebersole BJ, Weinstein H, Sealfon SC. Conserved helix 7 tyrosine acts as a multistate conformational switch in the 5HT2C receptor. Identification of a novel "locked-on" phenotype and double revertant mutations. The Journal of Biological Chemistry. 277: 36577-84. PMID 12145300 DOI: 10.1074/Jbc.M206223200  0.358
2002 Yuen T, Wurmbach E, Ebersole BJ, Ruf F, Pfeffer RL, Sealfon SC. Coupling of GnRH concentration and the GnRH receptor-activated gene program. Molecular Endocrinology (Baltimore, Md.). 16: 1145-53. PMID 12040003 DOI: 10.1210/Mend.16.6.0853  0.368
2002 Yuen T, Zhang W, Ebersole BJ, Sealfon SC. Monitoring G-protein-coupled receptor signaling with DNA microarrays and real-time polymerase chain reaction. Methods in Enzymology. 345: 556-69. PMID 11665639 DOI: 10.1016/S0076-6879(02)45047-1  0.405
2002 Ebersole BJ, Sealfon SC. Strategies for mapping the binding site of the serotonin 5-HT2A receptor. Methods in Enzymology. 343: 123-36. PMID 11665561 DOI: 10.1016/S0076-6879(02)43130-8  0.338
2002 KRAKAUER DC, PAGE KM, SEALFON S. Module Dynamics of the GnRH Signal Transduction Network Journal of Theoretical Biology. 218: 457-470. DOI: 10.1006/Jtbi.2002.3092  0.321
2002 Visiers I, Ebersole BJ, Dracheva S, Ballesteros J, Sealfon SC, Weinstein H. Structural motifs as functional microdomains in G-protein-coupled receptors: Energetic considerations in the mechanism of activation of the serotonin 5-HT2A receptor by disruption of the ionic lock of the arginine cage International Journal of Quantum Chemistry. 88: 65-75. DOI: 10.1002/Qua.10078  0.355
2001 Wurmbach E, Yuen T, Ebersole BJ, Sealfon SC. Gonadotropin-releasing Hormone Receptor-coupled Gene Network Organization Journal of Biological Chemistry. 276: 47195-47201. PMID 11581274 DOI: 10.1074/Jbc.M108716200  0.367
2001 Sealfon SC. Polymorphisms 'r us Clinical Autonomic Research. 11: 59-60. PMID 11570602 DOI: 10.1007/Bf02322045  0.328
2001 Kitanovic S, Yuen T, Flanagan CA, Ebersole BJ, Sealfon SC. Insertional mutagenesis of the arginine cage domain of the gonadotropin-releasing hormone receptor. Molecular Endocrinology (Baltimore, Md.). 15: 390-7. PMID 11222740 DOI: 10.1210/Mend.15.3.0611  0.346
2001 Sun YM, Flanagan CA, Illing N, Ott TR, Sellar R, Fromme BJ, Hapgood J, Sharp P, Sealfon SC, Millar RP. A chicken gonadotropin-releasing hormone receptor that confers agonist activity to mammalian antagonists. Identification of D-Lys(6) in the ligand and extracellular loop two of the receptor as determinants. The Journal of Biological Chemistry. 276: 7754-61. PMID 11112780 DOI: 10.1074/Jbc.M009020200  0.376
2000 Rosendorff A, Ebersole BJ, Sealfon SC. Conserved helix 7 tyrosine functions as an activation relay in the serotonin 5HT(2C) receptor Molecular Brain Research. 84: 90-96. PMID 11113535 DOI: 10.1016/S0169-328X(00)00227-8  0.354
2000 Sealfon SC, Olanow CW. Dopamine receptors: From structure to behavior Trends in Neurosciences. 23: S34-S40. PMID 11052218 DOI: 10.1016/S1471-1931(00)00025-2  0.397
2000 Flanagan CA, Rodic V, Konvicka K, Yuen T, Chi L, Rivier JE, Millar RP, Weinstein H, Sealfon SC. Multiple interactions of the Asp(2.61(98)) side chain of the gonadotropin-releasing hormone receptor contribute differentially to ligand interaction. Biochemistry. 39: 8133-41. PMID 10889019 DOI: 10.1021/Bi000085G  0.315
2000 Klein C, Gurvich N, Sena-Esteves M, Bressman S, Brin MF, Ebersole BJ, Fink S, Forsgren L, Friedman J, Grimes D, Holmgren G, Kyllerman M, Lang AE, de Leon D, Leung J, ... ... Sealfon SC, et al. Evaluation of the role of the D2 dopamine receptor in myoclonus dystonia. Annals of Neurology. 47: 369-73. PMID 10716258 DOI: 10.1002/1531-8249(200003)47:3<369::Aid-Ana14>3.0.Co;2-9  0.313
1999 Flanagan CA, Zhou W, Chi L, Yuen T, Rodic V, Robertson D, Johnson M, Holland P, Millar RP, Weinstein H, Mitchell R, Sealfon SC. The functional microdomain in transmembrane helices 2 and 7 regulates expression, activation, and coupling pathways of the gonadotropin-releasing hormone receptor. The Journal of Biological Chemistry. 274: 28880-6. PMID 10506131 DOI: 10.1074/Jbc.274.41.28880  0.381
1999 Millar R, Conklin D, Lofton-Day C, Hutchinson E, Troskie B, Illing N, Sealfon SC, Hapgood J. A novel human GnRH receptor homolog gene: Abundant and wide tissue distribution of the antisense transcript Journal of Endocrinology. 162: 117-126. PMID 10396028 DOI: 10.1677/Joe.0.1620117  0.381
1999 Dracheva S, Xu M, Kelley KA, Haroutunian V, Holstein GR, Haun S, Silverstein JH, Sealfon SC. Paradoxical locomotor behavior of dopamine D1 receptor transgenic mice. Experimental Neurology. 157: 169-79. PMID 10222120 DOI: 10.1006/Exnr.1999.7037  0.322
1998 Ballesteros J, Kitanovic S, Guarnieri F, Davies P, Fromme BJ, Konvicka K, Chi L, Millar RP, Davidson JS, Weinstein H, Sealfon SC. Functional microdomains in G-protein-coupled receptors: The conserved arginine-cage motif in the gonadotropin-releasing hormone receptor Journal of Biological Chemistry. 273: 10445-10453. PMID 9553103 DOI: 10.1074/Jbc.273.17.10445  0.369
1998 Mitchell R, McCulloch D, Lutz E, Johnson M, MacKenzie C, Fennell M, Fink G, Zhou W, Sealfon SC. Rhodopsin-family receptors associate with small G proteins to activate phospholipase D Nature. 392: 411-414. PMID 9537328 DOI: 10.1038/32937  0.367
1997 Sealfon SC, Weinstein H, Millar RP. Molecular mechanisms of ligand interaction with the gonadotropin- releasing hormone receptor Endocrine Reviews. 18: 180-205. PMID 9101136 DOI: 10.1210/Edrv.18.2.0295  0.34
1996 Almaula N, Ebersole BJ, Zhang D, Weinstein H, Sealfon SC. Mapping the binding site pocket of the serotonin 5-hydroxytryptamine2A receptor: Ser3.36(159) provides a second interaction site for the protonated amine of serotonin but not of lysergic acid diethylamide or bufotenin Journal of Biological Chemistry. 271: 14672-14675. PMID 8663249 DOI: 10.1074/Jbc.271.25.14672  0.323
1996 Sealfon SC, Zhou W, Almaula N, Rodic V. [12] Cloning and site-directed mutagenesis studies of gonadotropin-releasing hormone receptor Methods in Neurosciences. 29: 143-169. DOI: 10.1016/S1043-9471(96)80048-6  0.371
1995 Sealfon SC, Millar RP. The gonadotrophin-releasing hormone receptor: Structural determinants and regulatory control Human Reproduction Update. 1: 216-230. PMID 9187940 DOI: 10.1093/Humupd/1.3.216  0.325
1995 Tsutsumi M, Laws SC, Rodic V, Sealfon SC. Translational regulation of the gonadotropin-releasing hormone receptor in αT3-1 cells Endocrinology. 136: 1128-1136. PMID 7867566 DOI: 10.1210/Endo.136.3.7867566  0.398
1995 Davidson JS, Flanagan CA, Zhou W, Becker II, Elario R, Emeran W, Sealfon SC, Millar RP. Identification of N-glycosylation sites in the gonadotropin-releasing hormone receptor: role in receptor expression but not ligand binding. Molecular and Cellular Endocrinology. 107: 241-5. PMID 7768336 DOI: 10.1016/0303-7207(94)03449-4  0.374
1995 Sealfon SC, Millar RP. Functional domains of the gonadotropin-releasing hormone receptor Cellular and Molecular Neurobiology. 15: 25-42. PMID 7648608 DOI: 10.1007/Bf02069557  0.362
1995 Zhou W, Rodic V, Kitanovic S, Flanagan CA, Chi L, Weinstein H, Maayani S, Millar RP, Sealfon SC. A locus of the gonadotropin-releasing hormone receptor that differentiates agonist and antagonist binding sites. The Journal of Biological Chemistry. 270: 18853-7. PMID 7642539 DOI: 10.1074/Jbc.270.32.18853  0.353
1995 Sealfon SC, Chi L, Ebersole BJ, Rodic V, Zhang D, Ballesteros JA, Weinstein H. Related contribution of specific helix 2 and 7 residues to conformational activation of the serotonin 5-HT2A receptor Journal of Biological Chemistry. 270: 16683-16688. PMID 7622478 DOI: 10.1074/Jbc.270.28.16683  0.343
1995 Sealfon SC. [1] Approaches to receptor cloning Methods in Neurosciences. 25: 3-8. DOI: 10.1016/S1043-9471(05)80031-X  0.342
1994 Wu JC, Sealfon SC, Miller WL. Gonadal hormones and gonadotropin-releasing hormone (GnRH) alter messenger ribonucleic acid levels for GnRH receptors in sheep Endocrinology. 134: 1846-1850. PMID 8137751 DOI: 10.1210/Endo.134.4.8137751  0.307
1994 Davidson JS, Flanagan CA, Becker II, Illing N, Sealfon SC, Millar RP. Molecular function of the gonadotropin-releasing hormone receptor: insights from site-directed mutagenesis. Molecular and Cellular Endocrinology. 100: 9-14. PMID 8056165 DOI: 10.1016/0303-7207(94)90271-2  0.322
1994 Zhou W, Sealfon SC. Structure of the mouse gonadotropin-releasing hormone receptor gene: Variant transcripts generated by alternative processing Dna and Cell Biology. 13: 605-614. PMID 8024703 DOI: 10.1089/Dna.1994.13.605  0.376
1993 Chi L, Zhou W, Prikhozhan A, Flanagan C, Davidson JS, Golembo M, Illing N, Millar RP, Sealfon SC. Cloning and characterization of the human GnRH receptor Molecular and Cellular Endocrinology. 91: R1-R6. PMID 8386108 DOI: 10.1016/0303-7207(93)90278-R  0.391
1993 Tsutsumi M, Laws SC, Sealfon SC. Homologous up-regulation of the gonadotropin-releasing hormone receptor in αT3-1 cells is associated with unchanged receptor messenger RNA (mRNA) levels and altered mRNA activity Molecular Endocrinology. 7: 1625-1633. PMID 8145768 DOI: 10.1210/Mend.7.12.8145768  0.411
1993 Illing N, Jacobs GF, Becker II, Flanagan CA, Davidson JS, Eales A, Zhou W, Sealfon SC, Millar RP. Comparative sequence analysis and functional characterization of the cloned sheep gonadotropin-releasing hormone receptor reveal differences in primary structure and ligand specificity among mammalian receptors. Biochemical and Biophysical Research Communications. 196: 745-51. PMID 7694577 DOI: 10.1006/Bbrc.1993.2312  0.39
1992 Huntley GW, Morrison JH, Prikhozhan A, Sealfon SC. Localization of multiple dopamine receptor subtype mRNAs in human and monkey motor cortex and striatum. Brain Research. Molecular Brain Research. 15: 181-8. PMID 1331674 DOI: 10.1016/0169-328X(92)90107-M  0.311
1992 Tsutsumi M, Zhou W, Millar RP, Mellon PL, Roberts JL, Flanagan CA, Dong K, Gillo B, Sealfon SC. Cloning and functional expression of a mouse gonadotropin-releasing hormone receptor. Molecular Endocrinology (Baltimore, Md.). 6: 1163-9. PMID 1324422 DOI: 10.1210/Mend.6.7.1324422  0.409
1992 Probst WC, Snyder LA, Schuster DI, Brosius J, Sealfon SC. Sequence alignment of the G-protein coupled receptor superfamily. Dna and Cell Biology. 11: 1-20. PMID 1310857 DOI: 10.1089/Dna.1992.11.1  0.331
1991 Snyder LA, Roberts JL, Sealfon SC. Alternative transcripts of the rat and human dopamine D3 receptor. Biochemical and Biophysical Research Communications. 180: 1031-5. PMID 1953708 DOI: 10.1016/S0006-291X(05)81169-6  0.327
1991 McChesney R, Sealfon SC, Tsutsumi M, Dong KW, Roberts JL, Bancroft C. Either isoform of the dopamine D2 receptor can mediate dopaminergic repression of the rat prolactin promoter. Molecular and Cellular Endocrinology. 79: R1-7. PMID 1834494 DOI: 10.1016/0303-7207(91)90110-E  0.375
1990 Sealfon SC, Gillo B, Mundamattom S, Mellon PL, Windle JJ, Landau E, Roberts JL. Gonadotropin-releasing hormone receptor expression in Xenopus oocytes. Molecular Endocrinology (Baltimore, Md.). 4: 119-24. PMID 2157973 DOI: 10.1210/Mend-4-1-119  0.32
1990 Sealfon SC, Laws SC, Wu JC, Gillo B, Miller WL. Hormonal regulation of gonadotropin-releasing hormone receptors and messenger RNA activity in ovine pituitary culture Molecular Endocrinology. 4: 1980-1987. PMID 1964491 DOI: 10.1210/Mend-4-12-1980  0.38
1989 Landau EM, Moriarty TM, Roberts JL, Gillo B, Sealfon S, Iyengar R. Expression of brain cholecystokinin receptors in frog oocytes Biological Psychiatry. 25: A130-A131. DOI: 10.1016/0006-3223(89)91749-6  0.319
1988 Moriarty TM, Gillo B, Sealfon S, Roberts JL, Blitzer RD, Landau EM. Functional expression of brain cholecystokinin and bombesin receptors in Xenopus oocytes. Brain Research. 464: 75-9. PMID 2902910 DOI: 10.1016/0169-328X(88)90021-6  0.337
Low-probability matches (unlikely to be authored by this person)
2005 Chan P, Gonzalez-Maeso J, Ruf F, Bishop DF, Hof PR, Sealfon SC. Epsilon-sarcoglycan immunoreactivity and mRNA expression in mouse brain. The Journal of Comparative Neurology. 482: 50-73. PMID 15612018 DOI: 10.1002/Cne.20377  0.3
2012 Zaslavsky E, Hayot F, Sealfon SC. Computational approaches to understanding dendritic cell responses to influenza virus infection. Immunologic Research. 54: 160-8. PMID 22544465 DOI: 10.1007/S12026-012-8322-6  0.299
2019 Whitman J, Dhanji A, Hayot F, Sealfon SC, Jayaprakash C. Spatio-temporal dynamics of Host-Virus competition: A model study of influenza A. Journal of Theoretical Biology. 484: 110026. PMID 31574283 DOI: 10.1016/J.Jtbi.2019.110026  0.299
1988 Moriarty TM, Gillo B, Sealfon S, Landau EM. Activation of ionic currents in Xenopus oocytes by corticotropin-releasing peptides. Brain Research. 464: 201-5. PMID 2850083 DOI: 10.1016/0169-328X(88)90026-5  0.298
2008 Bordería AV, Hartmann BM, Fernandez-Sesma A, Moran TM, Sealfon SC. Antiviral-activated dendritic cells: a paracrine-induced response state. Journal of Immunology (Baltimore, Md. : 1950). 181: 6872-81. PMID 18981106 DOI: 10.4049/Jimmunol.181.10.6872  0.297
2009 Sugár IP, Sealfon SC. Model of autocrine/paracrine signaling in epithelial layer: geometrical regulation of intercellular communication. The Journal of Physical Chemistry. B. 113: 10946-56. PMID 19601596 DOI: 10.1021/Jp903518X  0.296
2003 Wurmbach E, Yuen T, Sealfon SC. Focused microarray analysis. Methods (San Diego, Calif.). 31: 306-16. PMID 14597315 DOI: 10.1016/S1046-2023(03)00161-0  0.295
1989 Autelitano DJ, Snyder L, Sealfon SC, Roberts JL. Dopamine D2-receptor messenger RNA is differentially regulated by dopaminergic agents in rat anterior and neurointermediate pituitary. Molecular and Cellular Endocrinology. 67: 101-5. PMID 2575547 DOI: 10.1016/0303-7207(89)90235-9  0.294
2020 Rubenstein AB, Smith GR, Raue U, Begue G, Minchev K, Ruf-Zamojski F, Nair VD, Wang X, Zhou L, Zaslavsky E, Trappe TA, Trappe S, Sealfon SC. Single-cell transcriptional profiles in human skeletal muscle. Scientific Reports. 10: 229. PMID 31937892 DOI: 10.1038/S41598-019-57110-6  0.294
2007 Coppey M, Berezhkovskii AM, Sealfon SC, Shvartsman SY. Time and length scales of autocrine signals in three dimensions. Biophysical Journal. 93: 1917-22. PMID 17720734 DOI: 10.1529/Biophysj.107.109736  0.294
1993 Rappaport MS, Sealfon SC, Prikhozhan A, Huntley GW, Morrison JH. Heterogeneous distribution of D1, D2 and D5 receptor mRNAs in monkey striatum. Brain Research. 616: 242-50. PMID 8358616 DOI: 10.1016/0006-8993(93)90215-9  0.294
2015 Gorenshteyn D, Zaslavsky E, Fribourg M, Park CY, Wong AK, Tadych A, Hartmann BM, Albrecht RA, García-Sastre A, Kleinstein SH, Troyanskaya OG, Sealfon SC. Interactive Big Data Resource to Elucidate Human Immune Pathways and Diseases. Immunity. 43: 605-14. PMID 26362267 DOI: 10.1016/J.Immuni.2015.08.014  0.294
1991 Snyder LA, Roberts JL, Sealfon SC. Distribution of dopamine D2 receptor mRNA splice variants in the rat by solution hybridization/protection assay. Neuroscience Letters. 122: 37-40. PMID 1829147 DOI: 10.1016/0304-3940(91)90187-X  0.294
2004 Nair VD, Yuen T, Olanow CW, Sealfon SC. Early single cell bifurcation of pro- and antiapoptotic states during oxidative stress. The Journal of Biological Chemistry. 279: 27494-501. PMID 15078887 DOI: 10.1074/Jbc.M312135200  0.292
2006 Fernandez-Sesma A, Marukian S, Ebersole BJ, Kaminski D, Park MS, Yuen T, Sealfon SC, García-Sastre A, Moran TM. Influenza virus evades innate and adaptive immunity via the NS1 protein. Journal of Virology. 80: 6295-304. PMID 16775317 DOI: 10.1128/Jvi.02381-05  0.291
2014 Fribourg M, Hartmann B, Schmolke M, Marjanovic N, Albrecht RA, García-Sastre A, Sealfon SC, Jayaprakash C, Hayot F. Model of influenza A virus infection: dynamics of viral antagonism and innate immune response. Journal of Theoretical Biology. 351: 47-57. PMID 24594370 DOI: 10.1016/J.Jtbi.2014.02.029  0.29
2005 Tsokas P, Grace EA, Chan P, Ma T, Sealfon SC, Iyengar R, Landau EM, Blitzer RD. Local protein synthesis mediates a rapid increase in dendritic elongation factor 1A after induction of late long-term potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5833-43. PMID 15958750 DOI: 10.1523/Jneurosci.0599-05.2005  0.289
2017 Hartmann BM, Albrecht RA, Zaslavsky E, Nudelman G, Pincas H, Marjanovic N, Schotsaert M, Martínez-Romero C, Fenutria R, Ingram JP, Ramos I, Fernandez-Sesma A, Balachandran S, García-Sastre A, Sealfon SC. Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death. Nature Communications. 8: 1931. PMID 29203926 DOI: 10.1038/S41467-017-02035-9  0.289
2018 Nudelman G, Frasca A, Kent B, Sadler KC, Sealfon SC, Walsh MJ, Zaslavsky E. High resolution annotation of zebrafish transcriptome using long-read sequencing. Genome Research. PMID 30061115 DOI: 10.1101/Gr.223586.117  0.288
2015 Hartmann BM, Thakar J, Albrecht RA, Avey S, Zaslavsky E, Marjanovic N, Chikina M, Fribourg M, Hayot F, Schmolke M, Meng H, Wetmur J, García-Sastre A, Kleinstein SH, Sealfon SC. Human Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses. Journal of Virology. 89: 10190-205. PMID 26223639 DOI: 10.1128/Jvi.01523-15  0.288
2002 Yuen T, Wurmbach E, Pfeffer RL, Ebersole BJ, Sealfon SC. Accuracy and calibration of commercial oligonucleotide and custom cDNA microarrays. Nucleic Acids Research. 30: e48. PMID 12000853 DOI: 10.1093/Nar/30.10.E48  0.288
2004 Gibson WT, Ebersole BJ, Bhattacharyya S, Clayton P, Farooqi IS, Sealfon SC, O'Rahilly S. Mutational analysis of the serotonin receptor 5HT2c in severe early-onset human obesity. Canadian Journal of Physiology and Pharmacology. 82: 426-9. PMID 15381968 DOI: 10.1139/Y04-025  0.287
2019 Lavin KM, Sealfon SC, McDonald MN, Roberts BM, Wilk K, Nair VD, Ge Y, Lakshman Kumar P, Windham ST, Bamman MM. Skeletal Muscle Transcriptional Networks Linked to Type I Myofiber Grouping in Parkinson's Disease. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 31829804 DOI: 10.1152/Japplphysiol.00702.2019  0.286
2006 Weisstaub NV, Zhou M, Lira A, Lambe E, González-Maeso J, Hornung JP, Sibille E, Underwood M, Itohara S, Dauer WT, Ansorge MS, Morelli E, Mann JJ, Toth M, Aghajanian G, ... Sealfon SC, et al. Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice. Science (New York, N.Y.). 313: 536-40. PMID 16873667 DOI: 10.1126/Science.1123432  0.286
2002 Song ZM, Undie AS, Koh PO, Fang YY, Zhang L, Dracheva S, Sealfon SC, Lidow MS. D1 dopamine receptor regulation of microtubule-associated protein-2 phosphorylation in developing cerebral cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6092-105. PMID 12122070 DOI: 10.1523/Jneurosci.22-14-06092.2002  0.286
2011 Albizu L, Holloway T, González-Maeso J, Sealfon SC. Functional crosstalk and heteromerization of serotonin 5-HT2A and dopamine D2 receptors. Neuropharmacology. 61: 770-7. PMID 21645528 DOI: 10.1016/J.Neuropharm.2011.05.023  0.285
2005 Busse PJ, Zhang TF, Srivastava K, Lin BP, Schofield B, Sealfon SC, Li XM. Chronic exposure to TNF-alpha increases airway mucus gene expression in vivo. The Journal of Allergy and Clinical Immunology. 116: 1256-63. PMID 16337454 DOI: 10.1016/J.Jaci.2005.08.059  0.285
2017 Fribourg M, Logothetis DE, González-Maeso J, Sealfon SC, Galocha-Iragüen B, Las-Heras Andrés F, Brezina V. Elucidation of molecular kinetic schemes from macroscopic traces using system identification. Plos Computational Biology. 13: e1005376. PMID 28192423 DOI: 10.1371/Journal.Pcbi.1005376  0.284
2011 Shtilbans A, Choi SG, Fowkes ME, Khitrov G, Shahbazi M, Ting J, Zhang W, Sun Y, Sealfon SC, Lange DJ. Differential gene expression in patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 12: 250-6. PMID 21375368 DOI: 10.3109/17482968.2011.560946  0.282
2013 Wang Q, Chikina M, Zaslavsky E, Pincas H, Sealfon SC. β-catenin regulates GnRH-induced FSHβ gene expression. Molecular Endocrinology (Baltimore, Md.). 27: 224-37. PMID 23211523 DOI: 10.1210/Me.2012-1310  0.281
2017 Sugár IP, Das J, Jayaprakash C, Sealfon SC. Multiscale Modeling of Complex Formation and CD80 Depletion during Immune Synapse Development. Biophysical Journal. 112: 997-1009. PMID 28297658 DOI: 10.1016/J.Bpj.2016.12.052  0.279
2015 Greene CS, Krishnan A, Wong AK, Ricciotti E, Zelaya RA, Himmelstein DS, Zhang R, Hartmann BM, Zaslavsky E, Sealfon SC, Chasman DI, FitzGerald GA, Dolinski K, Grosser T, Troyanskaya OG. Understanding multicellular function and disease with human tissue-specific networks. Nature Genetics. 47: 569-76. PMID 25915600 DOI: 10.1038/Ng.3259  0.279
2003 González-Maeso J, Yuen T, Ebersole BJ, Wurmbach E, Lira A, Zhou M, Weisstaub N, Hen R, Gingrich JA, Sealfon SC. Transcriptome fingerprints distinguish hallucinogenic and nonhallucinogenic 5-hydroxytryptamine 2A receptor agonist effects in mouse somatosensory cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8836-43. PMID 14523084  0.279
2006 Chan P, Lin G, Yuen T, Roysam B, Sealfon SC. Development of multiplex immunohistochemistry and in situ hybridization using colloidal quantum dots for semi-automated neuronal expression mapping in brain Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6096. DOI: 10.1117/12.661780  0.279
2000 Dracheva S, Haroutunian V, Grandy D, Sealfon S. 230. Characterization of the dopamine D1 receptor transgenic mice Biological Psychiatry. 47: S70. DOI: 10.1016/S0006-3223(00)00494-7  0.278
2009 Yuen T, Ruf F, Chu T, Sealfon SC. Microtranscriptome regulation by gonadotropin-releasing hormone. Molecular and Cellular Endocrinology. 302: 12-7. PMID 19356622 DOI: 10.1016/J.Mce.2008.12.013  0.278
2006 Nair VD, McNaught KS, González-Maeso J, Sealfon SC, Olanow CW. p53 mediates nontranscriptional cell death in dopaminergic cells in response to proteasome inhibition. The Journal of Biological Chemistry. 281: 39550-60. PMID 17060322 DOI: 10.1074/Jbc.M603950200  0.277
2009 González-Maeso J, Sealfon SC. Psychedelics and schizophrenia. Trends in Neurosciences. 32: 225-32. PMID 19269047 DOI: 10.1016/J.Tins.2008.12.005  0.277
2013 Zaslavsky E, Nudelman G, Marquez S, Hershberg U, Hartmann BM, Thakar J, Sealfon SC, Kleinstein SH. Reconstruction of regulatory networks through temporal enrichment profiling and its application to H1N1 influenza viral infection. Bmc Bioinformatics. 14: S1. PMID 23734902 DOI: 10.1186/1471-2105-14-S6-S1  0.276
2005 Mastaitis JW, Wurmbach E, Cheng H, Sealfon SC, Mobbs CV. Acute induction of gene expression in brain and liver by insulin-induced hypoglycemia. Diabetes. 54: 952-8. PMID 15793232 DOI: 10.2337/Diabetes.54.4.952  0.276
2007 Chu TT, Fink MY, Mong JA, John G, Auger AP, Ge Y, Sealfon SC. Effective use of microarrays in neuroendocrine research. Journal of Neuroendocrinology. 19: 145-61. PMID 17280588 DOI: 10.1111/J.1365-2826.2006.01523.X  0.273
1999 Shashidharan P, Chalmers-Redman RME, Carlile GW, Rodic V, Gurvich N, Yuen T, Tatton WG, Sealfon SC. Nuclear translocation of GAPDH-GFP fusion protein during apoptosis Neuroreport. 10: 1149-1153. PMID 10321500 DOI: 10.1097/00001756-199904060-00045  0.272
2014 Chikina MD, Sealfon SC. Increasing consistency of disease biomarker prediction across datasets. Plos One. 9: e91272. PMID 24740471 DOI: 10.1371/Journal.Pone.0091272  0.27
2008 Viswanathan G, Jayaprakash C, Sealfon SC, Hayot F. Shared kinase fluctuations between two enzymatic reactions. Physical Biology. 5: 046002. PMID 18997274 DOI: 10.1088/1478-3975/5/4/046002  0.269
1993 Spyraki C, Sealfon SC. Regulation of dopamine D2 receptor mRNA expression in the olfactory tubercle by cocaine Molecular Brain Research. 19: 313-317. PMID 8231734 DOI: 10.1016/0169-328X(93)90131-8  0.264
2013 Hartmann BM, Li W, Jia J, Patil S, Marjanovic N, Martínez-Romero C, Albrecht RA, Hayot F, García-Sastre A, Wetmur JG, Moran TM, Sealfon SC. Mouse dendritic cell (DC) influenza virus infectivity is much lower than that for human DCs and is hemagglutinin subtype dependent. Journal of Virology. 87: 1916-8. PMID 23192878 DOI: 10.1128/Jvi.02980-12  0.26
2009 Moreno JL, Sealfon SC, González-Maeso J. Group II metabotropic glutamate receptors and schizophrenia. Cellular and Molecular Life Sciences : Cmls. 66: 3777-85. PMID 19707855 DOI: 10.1007/S00018-009-0130-3  0.259
2015 Badgeley MA, Sealfon SC, Chikina MD. Hybrid Bayesian-rank integration approach improves the predictive power of genomic dataset aggregation. Bioinformatics (Oxford, England). 31: 209-15. PMID 25266226 DOI: 10.1093/Bioinformatics/Btu518  0.257
2015 Chikina MD, Gerald CP, Li X, Ge Y, Pincas H, Nair VD, Wong AK, Krishnan A, Troyanskaya OG, Raymond D, Saunders-Pullman R, Bressman SB, Yue Z, Sealfon SC. Low-variance RNAs identify Parkinson's disease molecular signature in blood. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 813-21. PMID 25786808 DOI: 10.1002/Mds.26205  0.257
2000 Sealfon SC. Dopamine receptors and locomotor responses: Molecular aspects Annals of Neurology. 47: S12-S21. PMID 10762128  0.254
1999 Troskie B, Illing N, Rumbak E, Sun YM, Hapgood J, Sealfon S, Conklin D, Millar R. Identification of three putative GnRH receptor subtypes in vertebrates. General and Comparative Endocrinology. 112: 296-302. PMID 9843635 DOI: 10.1006/gcen.1998.7156  0.252
2022 Lin YF, Schang G, Buddle ERS, Schultz H, Willis TL, Ruf-Zamojski F, Zamojski M, Mendelev N, Boehm U, Sealfon SC, Andoniadou CL, Bernard DJ. Steroidogenic factor 1 regulates transcription of the inhibin B co-receptor in pituitary gonadotrope cells. Endocrinology. PMID 35957608 DOI: 10.1210/endocr/bqac131  0.25
2018 Lee YS, Wong AK, Tadych A, Hartmann BM, Park CY, DeJesus VA, Ramos I, Zaslavsky E, Sealfon SC, Troyanskaya OG. Interpretation of an individual functional genomics experiment guided by massive public data. Nature Methods. PMID 30478325 DOI: 10.1038/S41592-018-0218-5  0.25
2005 Chan P, Yuen T, Ruf F, Gonzalez-Maeso J, Sealfon SC. Method for multiplex cellular detection of mRNAs using quantum dot fluorescent in situ hybridization. Nucleic Acids Research. 33: e161. PMID 16224100 DOI: 10.1093/Nar/Gni162  0.248
2011 Sealfon SC, Chu TT. RNA and DNA microarrays. Methods in Molecular Biology (Clifton, N.J.). 671: 3-34. PMID 20967621 DOI: 10.1007/978-1-59745-551-0_1  0.247
1995 Tojo K, Ichinose M, Nakayama M, Yamamoto H, Hasegawa T, Kawaguchi Y, Sealfon SC, Sakai O. A new family of Boucher-Neuhauser syndrome: Coexistence of Holmes type cerebellar atrophy, hypogonadotropic hypogonadism and retinochoroidal degeneration: Case reports and review of literature Endocrine Journal. 42: 367-376. PMID 7670566 DOI: 10.1507/Endocrj.42.367  0.246
2007 Viswanathan GA, Nudelman G, Patil S, Sealfon SC. BioPP: a tool for web-publication of biological networks. Bmc Bioinformatics. 8: 168. PMID 17519033 DOI: 10.1186/1471-2105-8-168  0.244
1994 Zhou W, Flanagan C, Ballesteros JA, Konvicka K, Davidson JS, Weinstein H, Millar RP, Sealfon SC. A reciprocal mutation supports helix 2 and helix 7 proximity in the gonadotropin-releasing hormone receptor Molecular Pharmacology. 45: 165-170. PMID 8114667  0.242
2023 Alonso CAI, David CD, Toufaily C, Wang Y, Zhou X, Ongaro L, Nudelman G, Nair VD, Ruf-Zamojski F, Boehm U, Sealfon SC, Bernard DJ. ATF3 stimulates FSHβ expression in vitro, but is dispensable for FSH production in murine gonadotropes in vivo. Endocrinology. PMID 36951304 DOI: 10.1210/endocr/bqad050  0.24
1989 Gillo B, Landau EM, Moriarty TM, Roberts JL, Sealfon SC. A novel calcium-dependent chloride current in Xenopus oocytes injected with brain messenger RNA. The Journal of Physiology. 417: 47-61. PMID 2482884 DOI: 10.1113/Jphysiol.1989.Sp017789  0.239
2009 Ge Y, Sealfon SC, Speed TP. Multiple testing and its applications to microarrays. Statistical Methods in Medical Research. 18: 543-63. PMID 20048384 DOI: 10.1177/0962280209351899  0.239
2020 Toneatti R, Shin JM, Shah UH, Mayer CR, Saunders JM, Fribourg M, Arsenovic PT, Janssen WG, Sealfon SC, López-Giménez JF, Benson DL, Conway DE, González-Maeso J. Interclass GPCR heteromerization affects localization and trafficking. Science Signaling. 13. PMID 33082287 DOI: 10.1126/scisignal.aaw3122  0.238
2013 Moreno JL, Holloway T, Umali A, Rayannavar V, Sealfon SC, González-Maeso J. Persistent effects of chronic clozapine on the cellular and behavioral responses to LSD in mice. Psychopharmacology. 225: 217-26. PMID 22842765 DOI: 10.1007/S00213-012-2809-7  0.235
2020 Wang X, Sathe AA, Smith GR, Ruf-Zamojski F, Nair V, Lavine KJ, Xing C, Sealfon SC, Zhou L. Heterogeneous origins and functions of mouse skeletal muscle-resident macrophages. Proceedings of the National Academy of Sciences of the United States of America. PMID 32796104 DOI: 10.1073/Pnas.1915950117  0.234
2020 Nair VD, Ge Y, Li S, Pincas H, Jain N, Seenarine N, Amper MAS, Goodpaster BH, Walsh MJ, Coen PM, Sealfon SC. Sedentary and Trained Older Men Have Distinct Circulating Exosomal microRNA Profiles at Baseline and in Response to Acute Exercise. Frontiers in Physiology. 11: 605. PMID 32587527 DOI: 10.3389/Fphys.2020.00605  0.233
2011 Sugár IP, González-Lergier J, Sealfon SC. Authors response to correspondence about an improved compensation method. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 79: 975-8. PMID 22065546 DOI: 10.1002/Cyto.A.21157  0.23
2007 Ge RS, Chen GR, Dong Q, Akingbemi B, Sottas CM, Santos M, Sealfon SC, Bernard DJ, Hardy MP. Biphasic effects of postnatal exposure to diethylhexylphthalate on the timing of puberty in male rats. Journal of Andrology. 28: 513-20. PMID 17287459 DOI: 10.2164/Jandrol.106.001909  0.228
2018 Medley JK, Choi K, König M, Smith L, Gu S, Hellerstein J, Sealfon SC, Sauro HM. Tellurium notebooks-An environment for reproducible dynamical modeling in systems biology. Plos Computational Biology. 14: e1006220. PMID 29906293 DOI: 10.1371/Journal.Pcbi.1006220  0.227
2020 Lavin KM, Ge Y, Sealfon SC, Nair VD, Wilk K, McAdam JS, Windham ST, Kumar PL, McDonald MN, Bamman MM. Rehabilitative Impact of Exercise Training on Human Skeletal Muscle Transcriptional Programs in Parkinson's Disease. Frontiers in Physiology. 11: 653. PMID 32625117 DOI: 10.3389/Fphys.2020.00653  0.226
1989 Moriarty TM, Sealfon SC, Carty DJ, Roberts JL, Iyengar R, Landau EM. Coupling of exogenous receptors to phospholipase C in Xenopus oocytes through pertussis toxin-sensitive and -insensitive pathways. Cross-talk through heterotrimeric G-proteins. The Journal of Biological Chemistry. 264: 13524-30. PMID 2474532  0.226
1994 Flanagan CA, Becker II, Davidson JS, Wakefield IK, Zhou W, Sealfon SC, Millar RP. Glutamate 301 of the mouse gonadotropin-releasing hormone receptor confers specificity for arginine 8 of mammalian gonadotropin-releasing hormone. The Journal of Biological Chemistry. 269: 22636-41. PMID 7915716  0.225
2016 Gómez HF, Hucka M, Keating SM, Nudelman G, Iber D, Sealfon SC. MOCCASIN: converting MATLAB ODE models to SBML. Bioinformatics (Oxford, England). PMID 26861819 DOI: 10.1093/Bioinformatics/Btw056  0.225
2011 Sugár IP, González-Lergier J, Sealfon SC. Improved compensation in flow cytometry by multivariable optimization. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 79: 356-60. PMID 21485003 DOI: 10.1002/Cyto.A.21062  0.223
2023 Zhang Z, Ruf-Zamojski F, Zamojski M, Bernard DJ, Chen X, Troyanskaya OG, Sealfon SC. Peak-agnostic high-resolution cis-regulatory circuitry mapping using single cell multiome data. Nucleic Acids Research. PMID 38084892 DOI: 10.1093/nar/gkad1166  0.219
2022 Zhang Z, Zamojski M, Smith GR, Willis TL, Yianni V, Mendelev N, Pincas H, Seenarine N, Amper MAS, Vasoya M, Cheng WS, Zaslavsky E, Nair VD, Turgeon JL, Bernard DJ, ... ... Sealfon SC, et al. Single nucleus transcriptome and chromatin accessibility of postmortem human pituitaries reveal diverse stem cell regulatory mechanisms. Cell Reports. 38: 110467. PMID 35263594 DOI: 10.1016/j.celrep.2022.110467  0.214
2023 Chen X, Wang Y, Cappuccio A, Cheng WS, Zamojski FR, Nair VD, Miller CM, Rubenstein AB, Nudelman G, Tadych A, Theesfeld CL, Vornholt A, George MC, Ruffin F, Dagher M, ... ... Sealfon SC, et al. Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data. Nature Computational Science. 3: 644-657. PMID 37974651 DOI: 10.1038/s43588-023-00476-5  0.206
2007 Ge Y, Sealfon SC, Tseng CH, Speed TP. A Holm-type procedure controlling the false discovery rate Statistics and Probability Letters. 77: 1756-1762. DOI: 10.1016/J.Spl.2007.04.019  0.205
2015 Gomez H, Hucka M, Keating S, Iber D, Sealfon S. MOCCASIN – a tool for converting MATLAB ODE models into reaction-based SBML F1000research. 6. DOI: 10.7490/F1000Research.1098305.1  0.204
1988 Call GK, Fleming MC, Sealfon S, Levine H, Kistler JP, Fisher CM. Reversible cerebral segmental vasoconstriction. Stroke; a Journal of Cerebral Circulation. 19: 1159-70. PMID 3046073 DOI: 10.1161/01.Str.19.9.1159  0.203
2012 Ge Y, Sealfon SC. flowPeaks: a fast unsupervised clustering for flow cytometry data via K-means and density peak finding. Bioinformatics (Oxford, England). 28: 2052-8. PMID 22595209 DOI: 10.1093/Bioinformatics/Bts300  0.203
2010 Sugár IP, Sealfon SC. Misty Mountain clustering: application to fast unsupervised flow cytometry gating. Bmc Bioinformatics. 11: 502. PMID 20932336 DOI: 10.1016/J.Bpj.2009.12.4043  0.202
2022 Schang G, Ongaro L, Brûlé E, Zhou X, Wang Y, Boehm U, Ruf-Zamojski F, Zamojski M, Mendelev N, Seenarine N, Amper MA, Nair V, Ge Y, Sealfon SC, Bernard DJ. Transcription factor GATA2 may potentiate follicle-stimulating hormone production in mice via induction of the BMP antagonist gremlin in gonadotrope cells. The Journal of Biological Chemistry. 102072. PMID 35643321 DOI: 10.1016/j.jbc.2022.102072  0.197
1996 Gillo B, Sealfon SC, Minke B. Pharmacology of a capacitative Ca2+ entry in Xenopus oocytes Journal of Photochemistry and Photobiology B: Biology. 35: 77-82. PMID 8823936 DOI: 10.1016/1011-1344(96)07303-4  0.195
2002 Krakauer DC, Page KM, Sealfon S. Module dynamics of the GnRH signal transduction network. Journal of Theoretical Biology. 218: 457-70. PMID 12384049  0.19
2018 Fribourg M, Logothetis DE, González-Maeso J, Sealfon SC, Galocha-Iragüen B, Las-Heras Andrés F, Brezina V. Correction: Elucidation of molecular kinetic schemes from macroscopic traces using system identification. Plos Computational Biology. 14: e1006539. PMID 30325915 DOI: 10.1371/Journal.Pcbi.1006539  0.186
2022 Cappuccio A, Chawla DG, Chen X, Rubenstein AB, Cheng WS, Mao W, Burke TW, Tsalik EL, Petzold E, Henao R, McClain MT, Woods CW, Chikina M, Troyanskaya OG, Sealfon SC, et al. Multi-objective optimization identifies a specific and interpretable COVID-19 host response signature. Cell Systems. 13: 989-1001.e8. PMID 36549275 DOI: 10.1016/j.cels.2022.11.008  0.182
2021 Ruf-Zamojski F, Zhang Z, Zamojski M, Smith GR, Mendelev N, Liu H, Nudelman G, Moriwaki M, Pincas H, Castanon RG, Nair VD, Seenarine N, Amper MAS, Zhou X, Ongaro L, ... ... Sealfon SC, et al. Single nucleus multi-omics regulatory landscape of the murine pituitary. Nature Communications. 12: 2677. PMID 33976139 DOI: 10.1038/s41467-021-22859-w  0.181
2021 Nudelman I, Kudrin D, Nudelman G, Deshpande R, Hartmann BM, Kleinstein SH, Myers CL, Sealfon SC, Zaslavsky E. Comparing Host Module Activation Patterns and Temporal Dynamics in Infection by Influenza H1N1 Viruses. Frontiers in Immunology. 12: 691758. PMID 34335598 DOI: 10.3389/fimmu.2021.691758  0.178
1996 Almaula N, Ebersole BJ, Ballesteros JA, Weinstein H, Sealfon SC. Contribution of a helix 5 locus to selectivity of hallucinogenic and nonhallucinogenic ligands for the human 5-hydroxytryptamine(2A) and 5- hydroxytryptamine(2C) receptors: Direct and indirect effects on ligand affinity mediated by the same locus Molecular Pharmacology. 50: 34-42. PMID 8700116  0.174
2002 Yu WH, Karanth S, Mastronardi CA, Sealfon S, Dean C, Dees WL, McCann SM. Lamprey GnRH-III acts on its putative receptor via nitric oxide to release follicle-stimulating hormone specifically. Experimental Biology and Medicine (Maywood, N.J.). 227: 786-93. PMID 12324658 DOI: 10.1177/153537020222700910  0.164
2021 Nair VD, Vasoya M, Nair V, Smith GR, Pincas H, Ge Y, Douglas CM, Esser KA, Sealfon SC. Differential analysis of chromatin accessibility and gene expression profiles identifies cis-regulatory elements in rat adipose and muscle. Genomics. 113: 3827-3841. PMID 34547403 DOI: 10.1016/j.ygeno.2021.09.013  0.162
2023 Smith GR, Zhao B, Lindholm ME, Raja A, Viggars M, Pincas H, Gay NR, Sun Y, Ge Y, Nair VD, Sanford JA, S Amper MA, Vasoya M, Smith KS, Montgomery S, ... ... Sealfon SC, et al. Multiomic identification of key transcriptional regulatory programs during endurance exercise training. Biorxiv : the Preprint Server For Biology. PMID 36711841 DOI: 10.1101/2023.01.10.523450  0.159
2021 Brûlé E, Wang Y, Li Y, Lin YF, Zhou X, Ongaro L, Alonso CAI, Buddle ERS, Schneyer AL, Byeon CH, Hinck CS, Mendelev N, Russell JP, Cowan M, Boehm U, ... ... Sealfon SC, et al. TGFBR3L is an inhibin B co-receptor that regulates female fertility. Science Advances. 7: eabl4391. PMID 34910520 DOI: 10.1126/sciadv.abl4391  0.159
2022 Fueyo-González F, McGinty M, Ningoo M, Anderson L, Cantarelli C, Demir M, Llaudó I, Purroy C, Marjanovic N, Heja D, Sealfon SC, Heeger PS, Cravedi P, Fribourg M. Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation. Immunity. PMID 35148827 DOI: 10.1016/j.immuni.2022.01.011  0.158
2021 Meyer M, Wang Y, Edwards D, Smith GR, Rubenstein AB, Ramanathan P, Mire CE, Pietzsch C, Chen X, Ge Y, Cheng WS, Henry C, Woods A, Ma L, Stewart-Jones GBE, ... ... Sealfon SC, et al. mRNA-1273 efficacy in a severe COVID-19 model: attenuated activation of pulmonary immune cells after challenge. Biorxiv : the Preprint Server For Biology. PMID 33532780 DOI: 10.1101/2021.01.25.428136  0.15
2023 Wang Y, Thistlethwaite W, Tadych A, Ruf-Zamojski F, Bernard DJ, Cappuccio A, Zaslavsky E, Chen X, Sealfon SC, Troyanskaya OG. Automated single-cell omics end-to-end framework with data-driven batch inference. Biorxiv : the Preprint Server For Biology. PMID 37961197 DOI: 10.1101/2023.11.01.564815  0.15
2022 Wang X, Chen J, Homma ST, Wang Y, Smith GR, Ruf-Zamojski F, Sealfon SC, Zhou L. Diverse effector and regulatory functions of fibro/adipogenic progenitors during skeletal muscle fibrosis in muscular dystrophy. Iscience. 26: 105775. PMID 36594034 DOI: 10.1016/j.isci.2022.105775  0.149
2020 Cappuccio A, Jensen ST, Hartmann BM, Sealfon SC, Soumelis V, Zaslavsky E. Deciphering the combinatorial landscape of immunity. Elife. 9. PMID 33225996 DOI: 10.7554/eLife.62148  0.147
2023 Rubenstein AB, Smith GR, Zhang Z, Chen X, Chambers TL, Ruf-Zamojski F, Mendelev N, Cheng WS, Zamojski M, Amper MAS, Nair VD, Marderstein AR, Montgomery SB, Troyanskaya OG, Zaslavsky E, ... ... Sealfon SC, et al. Integrated single-cell multiome analysis reveals muscle fiber-type gene regulatory circuitry modulated by endurance exercise. Biorxiv : the Preprint Server For Biology. PMID 37808658 DOI: 10.1101/2023.09.26.558914  0.146
2022 Ilinykh PA, Periasamy S, Huang K, Kuzmina NA, Ramanathan P, Meyer MN, Mire CE, Kuzmin IV, Bharaj P, Endsley JR, Chikina M, Sealfon SC, Widen SG, Endsley MA, Bukreyev A. A single intranasal dose of human parainfluenza virus type 3-vectored vaccine induces effective antibody and memory T cell response in the lungs and protects hamsters against SARS-CoV-2. Npj Vaccines. 7: 47. PMID 35468973 DOI: 10.1038/s41541-022-00471-3  0.146
2018 Papa L, Zimran E, Djedaini M, Ge Y, Ozbek U, Sebra R, Sealfon SC, Hoffman R. Ex vivo human HSC expansion requires coordination of cellular reprogramming with mitochondrial remodeling and p53 activation. Blood Advances. 2: 2766-2779. PMID 30348672 DOI: 10.1182/Bloodadvances.2018024273  0.14
2021 Meyer M, Wang Y, Edwards D, Smith GR, Rubenstein AB, Ramanathan P, Mire CE, Pietzsch C, Chen X, Ge Y, Cheng WS, Henry C, Woods A, Ma L, Stewart-Jones GB, ... ... Sealfon SC, et al. Attenuated activation of pulmonary immune cells in mRNA-1273 vaccinated hamsters after SARS-CoV-2 infection. The Journal of Clinical Investigation. PMID 34449440 DOI: 10.1172/JCI148036  0.137
2022 Aydillo T, Gonzalez-Reiche AS, Stadlbauer D, Amper MA, Nair VD, Mariottini C, Sealfon SC, van Bakel H, Palese P, Krammer F, García-Sastre A. Transcriptome signatures preceding the induction of anti-stalk antibodies elicited after universal influenza vaccination. Npj Vaccines. 7: 160. PMID 36496417 DOI: 10.1038/s41541-022-00583-w  0.135
2021 Ramos I, Goforth C, Soares-Schanoski A, Weir DL, Samuels EC, Phogat S, Meyer M, Huang K, Pietzsch CA, Ge Y, Pike BL, Regeimbal J, Simons MP, Termini MS, Vangeti S, ... ... Sealfon SC, et al. Antibody Responses to SARS-CoV-2 Following an Outbreak Among Marine Recruits With Asymptomatic or Mild Infection. Frontiers in Immunology. 12: 681586. PMID 34177926 DOI: 10.3389/fimmu.2021.681586  0.131
2023 Zhang Z, Sauerwald N, Cappuccio A, Ramos I, Nair VD, Nudelman G, Zaslavsky E, Ge Y, Gaitas A, Ren H, Brockman J, Geis J, Ramalingam N, King D, McClain MT, ... ... Sealfon SC, et al. Blood RNA alternative splicing events as diagnostic biomarkers for infectious disease. Cell Reports Methods. 3: 100395. PMID 36936082 DOI: 10.1016/j.crmeth.2023.100395  0.131
2022 Vangeti S, Periasamy S, Sun P, Balinsky CA, Mahajan AS, Kuzmina NA, Soares-Schanoski A, Cooper E, Beckett C, Marayag J, Marrone A, Nunez E, Ge Y, Porter CK, Goforth CW, ... ... Sealfon SC, et al. Serum Fc-Mediated Monocyte Phagocytosis Activity Is Stable for Several Months after SARS-CoV-2 Asymptomatic and Mildly Symptomatic Infection. Microbiology Spectrum. e0183722. PMID 36374040 DOI: 10.1128/spectrum.01837-22  0.13
2022 Soares-Schanoski A, Sauerwald N, Goforth CW, Periasamy S, Weir DL, Lizewski S, Lizewski R, Ge Y, Kuzmina NA, Nair VD, Vangeti S, Marjanovic N, Cappuccio A, Cheng WS, Mofsowitz S, ... ... Sealfon SC, et al. Asymptomatic SARS-CoV-2 Infection Is Associated With Higher Levels of Serum IL-17C, Matrix Metalloproteinase 10 and Fibroblast Growth Factors Than Mild Symptomatic COVID-19. Frontiers in Immunology. 13: 821730. PMID 35479098 DOI: 10.3389/fimmu.2022.821730  0.126
2022 Sauerwald N, Zhang Z, Ramos I, Nair VD, Soares-Schanoski A, Ge Y, Mao W, Alshammary H, Gonzalez-Reiche AS, van de Guchte A, Goforth CW, Lizewski RA, Lizewski SE, Amper MAS, Vasoya M, ... ... Sealfon SC, et al. Pre-infection antiviral innate immunity contributes to sex differences in SARS-CoV-2 infection. Cell Systems. PMID 36323307 DOI: 10.1016/j.cels.2022.10.005  0.125
2016 Vodovotz Y, Xia A, Read EL, Bassaganya-Riera J, Hafler DA, Sontag E, Wang J, Tsang JS, Day JD, Kleinstein SH, Butte AJ, Altman MC, Hammond R, Sealfon SC. Solving Immunology? Trends in Immunology. PMID 27986392 DOI: 10.1016/j.it.2016.11.006  0.125
2021 Hoehn KB, Ramanathan P, Unterman A, Sumida TS, Asashima H, Hafler DA, Kaminski N, Dela Cruz CS, Sealfon SC, Bukreyev A, Kleinstein SH. Cutting Edge: Distinct B Cell Repertoires Characterize Patients with Mild and Severe COVID-19. Journal of Immunology (Baltimore, Md. : 1950). PMID 34049971 DOI: 10.4049/jimmunol.2100135  0.124
2023 Meng H, Sengupta A, Ricciotti E, Mrčela A, Mathew D, Mazaleuskaya LL, Ghosh S, Brooks TG, Turner AP, Schanoski AS, Lahens NF, Tan AW, Woolfork A, Grant G, Susztak K, ... ... Sealfon SC, et al. Deep Phenotyping of the Lipidomic Response in COVID and non-COVID Sepsis. Biorxiv : the Preprint Server For Biology. PMID 37398323 DOI: 10.1101/2023.06.02.543298  0.121
2022 Sun P, Ramos I, Coelho CH, Grifoni A, Balinsky CA, Vangeti S, Tarke A, Bloom NI, Jani V, Jakubski SJ, Boulifard DA, Cooper E, Goforth CW, Marayag J, Marrone A, ... ... Sealfon SC, et al. Asymptomatic or symptomatic SARS-CoV-2 infection plus vaccination confers increased adaptive immunity to Variants of Concern. Iscience. 105202. PMID 36168391 DOI: 10.1016/j.isci.2022.105202  0.12
2023 Wang W, Hariharan M, Bartlett A, Barragan C, Castanon R, Rothenberg V, Song H, Nery J, Aldridge A, Altshul J, Kenworthy M, Ding W, Liu H, Tian W, Zhou J, ... ... Sealfon SC, et al. Human Immune Cell Epigenomic Signatures in Response to Infectious Diseases and Chemical Exposures. Biorxiv : the Preprint Server For Biology. PMID 37425926 DOI: 10.1101/2023.06.29.546792  0.119
2022 Chawla DG, Cappuccio A, Tamminga A, Sealfon SC, Zaslavsky E, Kleinstein SH. Benchmarking transcriptional host response signatures for infection diagnosis. Cell Systems. 13: 974-988.e7. PMID 36549274 DOI: 10.1016/j.cels.2022.11.007  0.118
2024 Chen X, Wang Y, Cappuccio A, Cheng WS, Zamojski FR, Nair VD, Miller CM, Rubenstein AB, Nudelman G, Tadych A, Theesfeld CL, Vornholt A, George MC, Ruffin F, Dagher M, ... ... Sealfon SC, et al. Author Correction: Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data. Nature Computational Science. 3: 805. PMID 38177788 DOI: 10.1038/s43588-023-00523-1  0.118
2022 Mendelev N, Zamojski M, Amper MAS, Cheng WS, Pincas H, Nair VD, Zaslavsky E, Sealfon SC, Ruf-Zamojski F. Multi-omics profiling of single nuclei from frozen archived postmortem human pituitary tissue. Star Protocols. 3: 101446. PMID 35693209 DOI: 10.1016/j.xpro.2022.101446  0.117
2022 Sedegah M, Porter C, Hollingdale MR, Ganeshan H, Huang J, Goforth CW, Belmonte M, Belmonte A, Weir DL, Lizewski RA, Lizewski SE, Sealfon SC, Jani V, Cheng Y, Inoue S, et al. CHARM: COVID-19 Health Action Response for Marines-Association of antigen-specific interferon-gamma and IL2 responses with asymptomatic and symptomatic infections after a positive qPCR SARS-CoV-2 test. Plos One. 17: e0266691. PMID 35390102 DOI: 10.1371/journal.pone.0266691  0.116
2023 Mao W, Miller CM, Nair VD, Ge Y, Amper MAS, Cappuccio A, George MC, Goforth CW, Guevara K, Marjanovic N, Nudelman G, Pincas H, Ramos I, Sealfon RSG, Soares-Schanoski A, ... ... Sealfon SC, et al. A methylation clock model of mild SARS-CoV-2 infection provides insight into immune dysregulation. Molecular Systems Biology. e11361. PMID 36919946 DOI: 10.15252/msb.202211361  0.115
2021 Letizia AG, Arnold CE, Adhikari BN, Voegtly LJ, Glang L, Rice GK, Goforth CW, Schilling MA, Weir DL, Malagon F, Ramos I, Vangeti S, Gonzalez-Reiche AS, Cer RZ, Sealfon SC, et al. Immunological and Genetic Investigation of SARS-CoV-2 Reinfection in an Otherwise Healthy, Young Marine Recruit. Pathogens (Basel, Switzerland). 10. PMID 34959544 DOI: 10.3390/pathogens10121589  0.111
2023 Meng H, Sengupta A, Ricciotti E, Mrčela A, Mathew D, Mazaleuskaya LL, Ghosh S, Brooks TG, Turner AP, Schanoski AS, Lahens NF, Tan AW, Woolfork A, Grant G, Susztak K, ... ... Sealfon SC, et al. Deep phenotyping of the lipidomic response in COVID-19 and non-COVID-19 sepsis. Clinical and Translational Medicine. 13: e1440. PMID 37948331 DOI: 10.1002/ctm2.1440  0.109
2019 Ruf-Zamojski F, Yongchao G, Pincas H, Shan J, Song Y, Montagna C, Hines N, Kelley K, Toufaily C, Bernard D, Nair V, Turgeon J, Sealfon S. SAT-414 Cytogenetic, Genomic, and Functional Characterization of Pituitary Gonadotrope Cell Lines Journal of the Endocrine Society. 3. DOI: 10.1210/js.2019-sat-414  0.108
2021 El Jamal SM, Pujadas E, Ramos I, Bryce C, Grimes ZM, Amanat F, Tsankova NM, Mussa Z, Olson S, Salem F, Miorin L, Aydillo T, Schotsaert M, Albrecht RA, Liu WC, ... ... Sealfon SC, et al. Tissue-Based SARS-Cov-2 Detection in Fatal COVID-19 Infections: Sustained Direct Viral-Induced Damage is Not Necessary to Drive Disease Progression. Human Pathology. PMID 33961839 DOI: 10.1016/j.humpath.2021.04.012  0.09
2022 Rubenstein AB, Hinkley JM, Nair VD, Nudelman G, Standley RA, Yi F, Yu G, Trappe TA, Bamman MM, Trappe SW, Sparks L, Goodpaster B, Vega RB, Sealfon SC, Zaslavsky E, et al. Skeletal muscle transcriptome response to a bout of endurance exercise in physically active and sedentary older adults. American Journal of Physiology. Endocrinology and Metabolism. PMID 35068187 DOI: 10.1152/ajpendo.00378.2021  0.079
2022 Kato Y, Bloom NI, Sun P, Balinsky CA, Qiu Q, Cheng Y, Jani V, Schilling MA, Goforth CW, Weir DL, Ramos I, Sealfon SC, Letizia AG, Crotty S. Memory B cell development after asymptomatic or mild symptomatic SARS-CoV-2 infection. The Journal of Infectious Diseases. PMID 35892131 DOI: 10.1093/infdis/jiac319  0.075
2022 Nair VD, Vasoya M, Nair V, Smith GR, Pincas H, Ge Y, Douglas CM, Esser KA, Sealfon SC. Optimization of the Omni-ATAC protocol to chromatin accessibility profiling in snap-frozen rat adipose and muscle tissues. Methodsx. 9: 101681. PMID 35464805 DOI: 10.1016/j.mex.2022.101681  0.073
2022 Cappuccio A, Geis J, Ge Y, Nair VD, Ramalingam N, Mao W, Chikina M, Letizia AG, Sealfon SC. Earlier detection of SARS-CoV-2 infection by blood RNA signature microfluidics assay. Clinical and Translational Discovery. 2: e47. PMID 35942160 DOI: 10.1002/ctd2.47  0.072
2008 Ge Y, Sealfon SC, Speed TP. SOME STEP-DOWN PROCEDURES CONTROLLING THE FALSE DISCOVERY RATE UNDER DEPENDENCE. Statistica Sinica. 18: 881-904. PMID 19018297  0.065
2008 Ge Y, Sealfon SC, Speed TP. Some step-down procedures controlling the false discovery rate under dependence Statistica Sinica. 18: 881-904.  0.065
2021 Letizia AG, Smith DR, Ge Y, Ramos I, Sealfon RSG, Goforth C, Gonzalez-Reiche AS, Vangeti S, Weir DL, Alshammary H, Chen HW, George MC, Soares-Schanoski A, Lizewski RA, Lizewski SE, ... ... Sealfon SC, et al. Viable virus shedding during SARS-CoV-2 reinfection. The Lancet. Respiratory Medicine. PMID 33964243 DOI: 10.1016/S2213-2600(21)00219-8  0.063
2021 Letizia AG, Ge Y, Goforth CW, Weir DL, Lizewski R, Lizewski S, Soares-Schanoski A, Vangeti S, Marjanovic N, Sealfon SC, Ramos I. SARS-CoV-2 Seropositivity among US Marine Recruits Attending Basic Training, United States, Spring-Fall 2020. Emerging Infectious Diseases. 27. PMID 33529569 DOI: 10.3201/eid2704.204732  0.058
1990 Sealfon SC, Mundamattom S, Gillo B. Modulation of calcium mobilization by guanosine 5'-O-(2-thiodiphosphate) in Xenopus oocytes. Febs Letters. 269: 135-8. PMID 2387392 DOI: 10.1016/0014-5793(90)81138-E  0.058
2022 Lizewski RA, Sealfon RSG, Park SW, Smith GR, Porter CK, Gonzalez-Reiche AS, Ge Y, Miller CM, Goforth CW, Pincas H, Termini MS, Ramos I, Nair VD, Lizewski SE, Alshammary H, ... ... Sealfon SC, et al. SARS-CoV-2 outbreak dynamics in an isolated US military recruit training center with rigorous prevention measures. Epidemiology (Cambridge, Mass.). PMID 35944149 DOI: 10.1097/EDE.0000000000001523  0.054
2023 Raue U, Begue G, Minchev K, Jemiolo B, Gries KJ, Chambers T, Rubenstein A, Zaslavsky E, Sealfon SC, Trappe T, Trappe S. Fast and Slow Muscle Fiber Transcriptome Dynamics with Lifelong Endurance Exercise. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 38095016 DOI: 10.1152/japplphysiol.00442.2023  0.053
2020 Nair VD, Ge Y, Li S, Pincas H, Jain N, Seenarine N, Amper MAS, Goodpaster BH, Walsh MJ, Coen PM, Sealfon SC. Sedentary and Trained Older Men Have Distinct Circulating Exosomal microRNA Profiles at Baseline and in Response to Acute Exercise Frontiers in Physiology. 11. DOI: 10.3389/fphys.2020.00605  0.048
2021 Letizia AG, Ge Y, Vangeti S, Goforth C, Weir DL, Kuzmina NA, Balinsky CA, Chen HW, Ewing D, Soares-Schanoski A, George MC, Graham WD, Jones F, Bharaj P, Lizewski RA, ... ... Sealfon SC, et al. SARS-CoV-2 seropositivity and subsequent infection risk in healthy young adults: a prospective cohort study. The Lancet. Respiratory Medicine. PMID 33865504 DOI: 10.1016/S2213-2600(21)00158-2  0.048
2022 Letizia AG, Goforth CW, Ge Y, Termini MS, Schilling MA, Sugiharto VA, Chen HW, Ramos I, Sealfon SC. Lessons Learned From a Prospective Observational Study of U.S. Marine Recruits During a Supervised Quarantine, Spring‒Fall 2020. Ajpm Focus. 1: 100003. PMID 36896336 DOI: 10.1016/j.focus.2022.100003  0.045
2020 Lavin KM, Ge Y, Sealfon SC, Nair VD, Wilk K, McAdam JS, Windham ST, Kumar PL, McDonald MN, Bamman MM. Rehabilitative Impact of Exercise Training on Human Skeletal Muscle Transcriptional Programs in Parkinson’s Disease Frontiers in Physiology. 11. DOI: 10.3389/fphys.2020.00653  0.044
2020 Letizia AG, Ramos I, Obla A, Goforth C, Weir DL, Ge Y, Bamman MM, Dutta J, Ellis E, Estrella L, George MC, Gonzalez-Reiche AS, Graham WD, van de Guchte A, Gutierrez R, ... ... Sealfon SC, et al. SARS-CoV-2 Transmission among Marine Recruits during Quarantine. The New England Journal of Medicine. PMID 33176093 DOI: 10.1056/NEJMoa2029717  0.042
1979 SNIDER BB, CONN RSE, SEALFON S. ChemInform Abstract: REACTIONS OF PHENYLHYDRAZONES WITH ELECTRON-DEFICIENT ALKENES Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197924218  0.019
1979 SNIDER BB, RODINI DJ, CONN RSE, SEALFON S. ChemInform Abstract: LEWIS ACID CATALYZED REACTIONS OF METHYL PROPIOLATE WITH UNACTIVATED ALKENES Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197951113  0.018
1979 Snider BB, Conn RSE, Sealfon S. Reactions of phenylhydrazones with electron-deficient alkenes The Journal of Organic Chemistry. 44: 218-221. DOI: 10.1021/Jo01316A012  0.017
1979 Snider BB, Rodini DJ, Conn RSE, Sealfon S. Lewis acid catalyzed reactions of methyl propiolate with unactivated alkenes Journal of the American Chemical Society. 101: 5283-5293. DOI: 10.1021/Ja00512A029  0.017
1995 Sealfon SC. Preface Methods in Neurosciences. 25: xiii. DOI: 10.1016/S1043-9471(05)80029-1  0.01
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