| Year |
Citation |
Score |
| 2021 |
Breitinger U, Sticht H, Breitinger HG. Modulation of recombinant human alpha 1 glycine receptor by flavonoids and gingerols. Biological Chemistry. PMID 33752269 DOI: 10.1515/hsz-2020-0360 |
0.333 |
|
| 2021 |
Zlotos DP, Abdelmalek CM, Botros LS, Banoub MM, Mandour YM, Breitinger U, El Nady A, Breitinger HG, Sotriffer C, Villmann C, Jensen AA, Holzgrabe U. C-2-Linked Dimeric Strychnine Analogues as Bivalent Ligands Targeting Glycine Receptors. Journal of Natural Products. PMID 33596384 DOI: 10.1021/acs.jnatprod.0c01030 |
0.361 |
|
| 2020 |
Saleh HA, Raafat KM, Temraz TA, Noureldin N, Breitinger HG, Breitinger U. Sarcophine and (7S, 8R)-Dihydroxydeepoxysarcophine from the Red Sea Soft Coral Sarcophyton glaucum as in vitro and in vivo Modulators of Glycine Receptors. Neurotoxicology. PMID 32702364 DOI: 10.1016/j.neuro.2020.07.002 |
0.311 |
|
| 2020 |
Breitinger U, Breitinger HG. Modulators of the inhibitory glycine receptor. Acs Chemical Neuroscience. PMID 32391682 DOI: 10.1021/acschemneuro.0c00054 |
0.377 |
|
| 2020 |
Langlhofer G, Schaefer N, Maric HM, Keramidas A, Zhang Y, Baumann P, Blum R, Breitinger U, Strømgaard K, Schlosser A, Kessels MM, Koch D, Qualmann B, Breitinger HG, Lynch JW, et al. A novel glycine receptor variant with startle disease affects syndapin I and glycinergic inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32354853 DOI: 10.1523/Jneurosci.2490-19.2020 |
0.311 |
|
| 2019 |
Zlotos DP, Mohsen AMY, Mandour YM, Marzouk MA, Breitinger U, Villmann C, Breitinger HG, Sotriffer C, Jensen AA, Holzgrabe U. 11-Aminostrychnine and -(Strychnine-11-yl)propionamide: Synthesis, Configuration, and Pharmacological Evaluation at Glycine Receptors. Journal of Natural Products. PMID 31385511 DOI: 10.1021/Acs.Jnatprod.9B00180 |
0.366 |
|
| 2018 |
Breitinger U, Bahnassawy LM, Janzen D, Roemer V, Becker CM, Villmann C, Breitinger HG. PKA and PKC Modulators Affect Ion Channel Function and Internalization of Recombinant Alpha1 and Alpha1-Beta Glycine Receptors. Frontiers in Molecular Neuroscience. 11: 154. PMID 29867346 DOI: 10.3389/Fnmol.2018.00154 |
0.322 |
|
| 2016 |
Mohsen AM, Mandour YM, Sarukhanyan E, Breitinger U, Villmann C, Banoub MM, Breitinger HG, Dandekar T, Holzgrabe U, Sotriffer C, Jensen AA, Zlotos DP. Oxime Ethers of (E)-11-Isonitrosostrychnine as Highly Potent Glycine Receptor Antagonists. Journal of Natural Products. PMID 27966945 DOI: 10.1021/Acs.Jnatprod.6B00479 |
0.345 |
|
| 2011 |
Alqazzaz M, Thompson AJ, Price KL, Breitinger HG, Lummis SC. Cys-loop receptor channel blockers also block GLIC. Biophysical Journal. 101: 2912-8. PMID 22208189 DOI: 10.1016/j.bpj.2011.10.055 |
0.38 |
|
| 2010 |
Raafat K, Breitinger U, Mahran L, Ayoub N, Breitinger HG. Synergistic inhibition of glycinergic transmission in vitro and in vivo by flavonoids and strychnine. Toxicological Sciences : An Official Journal of the Society of Toxicology. 118: 171-82. PMID 20719748 DOI: 10.1093/toxsci/kfq245 |
0.317 |
|
| 2009 |
Breitinger HG, Villmann C, Melzer N, Rennert J, Breitinger U, Schwarzinger S, Becker CM. Novel regulatory site within the TM3-4 loop of human recombinant alpha3 glycine receptors determines channel gating and domain structure. The Journal of Biological Chemistry. 284: 28624-33. PMID 19661067 DOI: 10.1074/Jbc.M109.043174 |
0.344 |
|
| 2007 |
Breitinger H, Becker K, Rennert J, Vohwinkel C, Becker C. Assembly of ligand-gated ion channel receptors – how individual subunits contribute to receptor function Bmc Neuroscience. 8. DOI: 10.1186/1471-2202-8-S1-P37 |
0.341 |
|
| 2004 |
Breitinger HG, Lanig H, Vohwinkel C, Grewer C, Breitinger U, Clark T, Becker CM. Molecular dynamics simulation links conformation of a pore-flanking region to hyperekplexia-related dysfunction of the inhibitory glycine receptor. Chemistry & Biology. 11: 1339-50. PMID 15489161 DOI: 10.1016/J.Chembiol.2004.07.008 |
0.631 |
|
| 2003 |
Banerjee A, Grewer C, Ramakrishnan L, Jäger J, Gameiro A, Breitinger HG, Gee KR, Carpenter BK, Hess GP. Toward the development of new photolabile protecting groups that can rapidly release bioactive compounds upon photolysis with visible light. The Journal of Organic Chemistry. 68: 8361-7. PMID 14575458 DOI: 10.1021/Jo0300643 |
0.551 |
|
| 2002 |
Breitinger HG, Becker CM. The inhibitory glycine receptor-simple views of a complicated channel. Chembiochem : a European Journal of Chemical Biology. 3: 1042-52. PMID 12404628 DOI: 10.1002/1439-7633(20021104)3:11<1042::AID-CBIC1042>3.0.CO;2-7 |
0.408 |
|
| 2002 |
Breitinger HG, Becker CM. Statistical coassembly of glycine receptor alpha1 wildtype and the hyperekplexia mutant alpha1(P250T) in HEK 293 cells: impaired channel function is not dominant in the recombinant system. Neuroscience Letters. 331: 21-4. PMID 12359314 DOI: 10.1016/S0304-3940(02)00773-5 |
0.32 |
|
| 2002 |
Breitinger HG, Villmann C, Rennert J, Ballhausen D, Becker CM. Hydroxylated residues influence desensitization behaviour of recombinant alpha3 glycine receptor channels. Journal of Neurochemistry. 83: 30-6. PMID 12358726 DOI: 10.1046/J.1471-4159.2002.01109.X |
0.394 |
|
| 2001 |
Breitinger HG. Fast kinetic analysis of ligand-gated ion channels. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 7: 95-103. PMID 11496930 |
0.308 |
|
| 2001 |
Breitinger HG, Geetha N, Hess GP. Inhibition of the serotonin 5-HT3 receptor by nicotine, cocaine, and fluoxetine investigated by rapid chemical kinetic techniques. Biochemistry. 40: 8419-29. PMID 11444989 DOI: 10.1021/Bi0106890 |
0.711 |
|
| 2001 |
Breitinger HG, Villmann C, Becker K, Becker CM. Opposing effects of molecular volume and charge at the hyperekplexia site alpha 1(P250) govern glycine receptor activation and desensitization. The Journal of Biological Chemistry. 276: 29657-63. PMID 11395484 DOI: 10.1074/Jbc.M100446200 |
0.331 |
|
| 2000 |
Hess GP, Ulrich H, Breitinger HG, Niu L, Gameiro AM, Grewer C, Srivastava S, Ippolito JE, Lee SM, Jayaraman V, Coombs SE. Mechanism-based discovery of ligands that counteract inhibition of the nicotinic acetylcholine receptor by cocaine and MK-801. Proceedings of the National Academy of Sciences of the United States of America. 97: 13895-900. PMID 11095713 DOI: 10.1073/Pnas.240459497 |
0.605 |
|
| 2000 |
Breitinger HG, Wieboldt R, Ramesh D, Carpenter BK, Hess GP. Synthesis and characterization of photolabile derivatives of serotonin for chemical kinetic investigations of the serotonin 5-HT(3) receptor. Biochemistry. 39: 5500-8. PMID 10820023 DOI: 10.1021/Bi992781Q |
0.649 |
|
| 1998 |
Breitinger HG, Becker CM. The inhibitory glycine receptor: prospects for a therapeutic orphan? Current Pharmaceutical Design. 4: 315-34. PMID 10197046 |
0.357 |
|
| 1997 |
Walseth TF, Aarhus R, Gurnack ME, Wong L, Breitinger HG, Gee KR, Lee HC. Preparation of cyclic ADP-ribose antagonists and caged cyclic ADP-ribose. Methods in Enzymology. 280: 294-305. PMID 9211325 DOI: 10.1016/S0076-6879(97)80121-8 |
0.305 |
|
| 1997 |
Breitinger HG, Hess GP. Transient kinetic investigations of the inhibition of the 5-ht-4 serotonin receptor by nicotine Faseb Journal. 11: A969. |
0.608 |
|
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