Year |
Citation |
Score |
2024 |
Mei M, Cupic A, Miorin L, Ye C, Cagatay T, Zhang K, Patel K, Wilson N, McDonald WH, Crossland NA, Lo M, Rutkowska M, Aslam S, Mena I, Martinez-Sobrido L, et al. Inhibition of mRNA nuclear export promotes SARS-CoV-2 pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 121: e2314166121. PMID 38768348 DOI: 10.1073/pnas.2314166121 |
0.305 |
|
2024 |
Fernández JJ, Marín A, Rosales R, Penrice-Randal R, Mlcochova P, Alvarez Y, Villalón-Letelier F, Yildiz S, Pérez E, Rathnasinghe R, Cupic A, Kehrer T, Uccellini MB, Alonso S, Martínez F, et al. The IRE1α-XBP1 arm of the unfolded protein response is a host factor activated in SARS-CoV-2 infection. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 1870: 167193. PMID 38648902 DOI: 10.1016/j.bbadis.2024.167193 |
0.419 |
|
2024 |
Huang C, Yu L, Xu Y, Huang J, Qin Y, Guo X, Zeng Y, Qin Y, Ouyang K, Wei Z, Huang W, García-Sastre A, Chen Y. Long-term co-circulation of multiple influenza A viruses in pigs, Guangxi, China. Emerging Microbes & Infections. 13: 2337673. PMID 38572517 DOI: 10.1080/22221751.2024.2337673 |
0.334 |
|
2023 |
Kessler S, García-Sastre A, Schwemmle M, Ciminski K. Reverse Genetics of Bat Influenza A Viruses. Methods in Molecular Biology (Clifton, N.J.). 2733: 75-86. PMID 38064027 DOI: 10.1007/978-1-0716-3533-9_5 |
0.371 |
|
2023 |
Cobela-García A, Mena I, García-Sastre A. Rescue of Recombinant Newcastle Disease Virus Expressing Heterologous Genes. Methods in Molecular Biology (Clifton, N.J.). 2733: 37-46. PMID 38064025 DOI: 10.1007/978-1-0716-3533-9_3 |
0.397 |
|
2023 |
Bykov Y, Dawodu G, Javaheri A, Garcia-Sastre A, Cuadrado-Castano S. Immune responses elicited by ssRNA(-) oncolytic viruses in the host and in the tumor microenvironment. Journal of Cancer Metastasis and Treatment. 9. PMID 37974615 DOI: 10.20517/2394-4722.2022.92 |
0.4 |
|
2023 |
Kusakabe T, Lin WY, Cheong JG, Singh G, Ravishankar A, Yeung ST, Mesko M, DeCelie MB, Carriche G, Zhao Z, Rand S, Doron I, Putzel GG, Worgall S, Cushing M, et al. Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19. Nature Immunology. 24: 1879-1889. PMID 37872315 DOI: 10.1038/s41590-023-01637-4 |
0.599 |
|
2023 |
Haas KM, McGregor MJ, Bouhaddou M, Polacco BJ, Kim EY, Nguyen TT, Newton BW, Urbanowski M, Kim H, Williams MAP, Rezelj VV, Hardy A, Fossati A, Stevenson EJ, Sukerman E, et al. Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets. Nature Communications. 14: 6030. PMID 37758692 DOI: 10.1038/s41467-023-41442-z |
0.433 |
|
2023 |
Kehrer T, Cupic A, Ye C, Yildiz S, Bouhaddou M, Crossland NA, Barrall EA, Cohen P, Tseng A, Çağatay T, Rathnasinghe R, Flores D, Jangra S, Alam F, Mena I, et al. Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis. Cell Host & Microbe. PMID 37738983 DOI: 10.1016/j.chom.2023.08.003 |
0.397 |
|
2023 |
Bouhaddou M, Reuschl AK, Polacco BJ, Thorne LG, Ummadi MR, Ye C, Rosales R, Pelin A, Batra J, Jang GM, Xu J, Moen JM, Richards AL, Zhou Y, Harjai B, ... ... Garcia-Sastre A, et al. SARS-CoV-2 variants evolve convergent strategies to remodel the host response. Cell. PMID 37738970 DOI: 10.1016/j.cell.2023.08.026 |
0.389 |
|
2023 |
Thomas SN, Niemeyer BF, Jimenez-Valdes RJ, Kaiser AJ, Espinosa JM, Sullivan KD, Goodspeed A, Costello JC, Alder JK, Cañas-Arranz R, García-Sastre A, Benam KH. Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection. Iscience. 26: 107361. PMID 37554445 DOI: 10.1016/j.isci.2023.107361 |
0.323 |
|
2023 |
Kottur J, White KM, Rodriguez ML, Rechkoblit O, Quintana-Feliciano R, Nayar A, García-Sastre A, Aggarwal AK. Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals. Plos Pathogens. 19: e1011546. PMID 37523415 DOI: 10.1371/journal.ppat.1011546 |
0.324 |
|
2023 |
Castaneda DC, Jangra S, Yurieva M, Martinek J, Callender M, Coxe M, Choi A, García-Bernalt Diego J, Lin J, Wu TC, Marches F, Chaussabel D, Yu P, Salner A, Aucello G, et al. Spatiotemporally organized immunomodulatory response to SARS-CoV-2 virus in primary human broncho-alveolar epithelia. Iscience. 26: 107374. PMID 37520727 DOI: 10.1016/j.isci.2023.107374 |
0.414 |
|
2023 |
Paniz-Mondolfi A, Reidy J, Pagani N, Lednicky JA, McGrail JP, Kasminskaya Y, Patino LH, Garcia-Sastre A, Palacios G, Gonzalez-Reiche AS, van Bakel H, Firpo Betancourt A, Hernandez MM, Cordon-Cardo C, Simon V, et al. Genomic and ultrastructural analysis of monkeypox virus in skin lesions and in human/animal infected cells reveals further morphofunctional insights into viral pathogenicity. Journal of Medical Virology. 95: e28878. PMID 37322614 DOI: 10.1002/jmv.28878 |
0.351 |
|
2023 |
Bhat P, Aksenova V, Gazzara M, Rex EA, Aslam S, Haddad C, Gao S, Esparza M, Cagatay T, Batten K, El Zahed SS, Arnaoutov A, Zhong H, Shay JW, Tolbert BS, et al. Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex. Nature Communications. 14: 2304. PMID 37085480 DOI: 10.1038/s41467-023-37911-0 |
0.335 |
|
2023 |
Castaneda DC, Jangra S, Yurieva M, Martinek J, Callender M, Coxe M, Choi A, Diego JG, Lin J, Wu TC, Marches F, Chaussabel D, Yu P, Salner A, Aucello G, et al. Spatiotemporally organized immunomodulatory response to SARS-CoV-2 virus in primary human broncho-alveolar epithelia. Biorxiv : the Preprint Server For Biology. PMID 37034597 DOI: 10.1101/2023.03.30.534980 |
0.414 |
|
2023 |
Hemann EA, Knoll ML, Wilkins CR, Subra C, Green R, García-Sastre A, Thomas PG, Trautmann L, Ireton RC, Loo YM, Gale M. A Small Molecule RIG-I Agonist Serves as an Adjuvant to Induce Broad Multifaceted Influenza Virus Vaccine Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 36939421 DOI: 10.4049/jimmunol.2300026 |
0.367 |
|
2023 |
Wei J, Patil A, Collings CK, Alfajaro MM, Liang Y, Cai WL, Strine MS, Filler RB, DeWeirdt PC, Hanna RE, Menasche BL, Ökten A, Peña-Hernández MA, Klein J, McNamara A, et al. Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection. Nature Genetics. PMID 36894709 DOI: 10.1038/s41588-023-01307-z |
0.316 |
|
2023 |
Déjosez M, Marin A, Hughes GM, Morales AE, Godoy-Parejo C, Gray JL, Qin Y, Singh AA, Xu H, Juste J, Ibáñez C, White KM, Rosales R, Francoeur NJ, Sebra RP, et al. Bat pluripotent stem cells reveal unusual entanglement between host and viruses. Cell. PMID 36812912 DOI: 10.1016/j.cell.2023.01.011 |
0.358 |
|
2022 |
Pathak R, Eliscovich C, Mena I, Dixit U, García-Sastre A, Singer RH, Kalpana GV. Visualization of early RNA replication kinetics of SARS-CoV-2 by using single molecule RNA-FISH. Biorxiv : the Preprint Server For Biology. PMID 36561180 DOI: 10.1101/2022.12.10.517707 |
0.327 |
|
2022 |
Simba-Lahuasi A, Cantero-Camacho Á, Rosales R, McGovern BL, Rodríguez ML, Marchán V, White KM, García-Sastre A, Gallego J. SARS-CoV-2 Inhibitors Identified by Phenotypic Analysis of a Collection of Viral RNA-Binding Molecules. Pharmaceuticals (Basel, Switzerland). 15. PMID 36558898 DOI: 10.3390/ph15121448 |
0.341 |
|
2022 |
Meade P, Strohmeier S, Bermúdez-González MC, García-Sastre A, Palese P, Simon V, Krammer F. Antigenic Landscape Analysis of Individuals Vaccinated with a Universal Influenza Virus Vaccine Candidate Reveals Induction of Cross-Subtype Immunity. Journal of Virology. e0107022. PMID 36533948 DOI: 10.1128/jvi.01070-22 |
0.317 |
|
2022 |
Diaz-Beneitez E, Cubas-Gaona LL, Candelas-Rivera O, Benito-Zafra A, Sánchez-Aparicio MT, Miorin L, Rodríguez JF, García-Sastre A, Rodríguez D. Interaction between chicken TRIM25 and MDA5 and their role in mediated antiviral activity against IBDV infection. Frontiers in Microbiology. 13: 1068328. PMID 36519174 DOI: 10.3389/fmicb.2022.1068328 |
0.426 |
|
2022 |
Kehrer T, Cupic A, Ye C, Yildiz S, Bouhhadou M, Crossland NA, Barrall E, Cohen P, Tseng A, Çağatay T, Rathnasinghe R, Flores D, Jangra S, Alam F, Mena N, et al. Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis. Biorxiv : the Preprint Server For Biology. PMID 36299428 DOI: 10.1101/2022.10.18.512708 |
0.401 |
|
2022 |
Forst CV, Martin-Sancho L, Tripathi S, Wang G, Dos Anjos Borges LG, Wang M, Geber A, Lashua L, Ding T, Zhou X, Carter CE, Metreveli G, Rodriguez-Frandsen A, Urbanowski MD, White KM, et al. Common and species-specific molecular signatures, networks, and regulators of influenza virus infection in mice, ferrets, and humans. Science Advances. 8: eabm5859. PMID 36197970 DOI: 10.1126/sciadv.abm5859 |
0.354 |
|
2022 |
Seoane R, Llamas-González YY, Vidal S, El Motiam A, Bouzaher YH, Fonseca D, Farrás R, García-Sastre A, González-Santamaría J, Rivas C. eIF5A is activated by virus infection or dsRNA and facilitates virus replication through modulation of interferon production. Frontiers in Cellular and Infection Microbiology. 12: 960138. PMID 35967877 DOI: 10.3389/fcimb.2022.960138 |
0.521 |
|
2022 |
Javaheri A, Bykov Y, Mena I, García-Sastre A, Cuadrado-Castano S. Avian Paramyxovirus 4 Antitumor Activity Leads to Complete Remissions and Long-term Protective Memory in Preclinical Melanoma and Colon Carcinoma Models. Cancer Research Communications. 2: 602-615. PMID 35937459 DOI: 10.1158/2767-9764.crc-22-0025 |
0.342 |
|
2022 |
Günther SC, Martínez-Romero C, Sempere Borau M, Pham CTN, García-Sastre A, Stertz S. Proteomic Identification of Potential Target Proteins of Cathepsin W for Its Development as a Drug Target for Influenza. Microbiology Spectrum. e0092122. PMID 35867415 DOI: 10.1128/spectrum.00921-22 |
0.4 |
|
2022 |
Pohl MO, Martin-Sancho L, Ratnayake R, White KM, Riva L, Chen QY, Lieber G, Busnadiego I, Yin X, Lin S, Pu Y, Pache L, Rosales R, Déjosez M, Qin Y, et al. Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV-2 and Exhibits Broad-Spectrum Antiviral Activity. Acs Infectious Diseases. PMID 35766385 DOI: 10.1021/acsinfecdis.2c00008 |
0.443 |
|
2022 |
Gao S, Esparza M, Dehghan I, Aksenova V, Zhang K, Batten K, Ferretti MB, Begg BE, Cagatay T, Shay JW, García-Sastre A, Goldsmith EJ, Chen ZJ, Dasso M, Lynch KW, et al. Nuclear speckle integrity and function require TAO2 kinase. Proceedings of the National Academy of Sciences of the United States of America. 119: e2206046119. PMID 35704758 DOI: 10.1073/pnas.2206046119 |
0.389 |
|
2022 |
Pisanelli G, Pagnini U, Iovane G, García-Sastre A. Type I and Type II Interferon Antagonism Strategies Used by : Previous and New Discoveries, in Comparison. Viruses. 14. PMID 35632848 DOI: 10.3390/v14051107 |
0.404 |
|
2022 |
Nogales A, Steel J, Liu WC, Lowen AC, Rodriguez L, Chiem K, Cox A, García-Sastre A, Albrecht RA, Dewhurst S, Martínez-Sobrido L. Mutation L319Q in the PB1 Polymerase Subunit Improves Attenuation of a Candidate Live-Attenuated Influenza A Virus Vaccine. Microbiology Spectrum. e0007822. PMID 35583364 DOI: 10.1128/spectrum.00078-22 |
0.308 |
|
2022 |
Hage A, Bharaj P, van Tol S, Giraldo MI, Gonzalez-Orozco M, Valerdi KM, Warren AN, Aguilera-Aguirre L, Xie X, Widen SG, Moulton HM, Lee B, Johnson JR, Krogan NJ, García-Sastre A, et al. The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity. Cell Reports. 38: 110434. PMID 35263596 DOI: 10.1016/j.celrep.2022.110434 |
0.4 |
|
2022 |
Dang R, Rodgers VGJ, García-Sastre A, Liao J. Human SUMOylation Pathway Is Critical for Influenza B Virus. Viruses. 14. PMID 35215907 DOI: 10.3390/v14020314 |
0.405 |
|
2022 |
Miorin L, Mire CE, Ranjbar S, Hume AJ, Huang J, Crossland NA, White KM, Laporte M, Kehrer T, Haridas V, Moreno E, Nambu A, Jangra S, Cupic A, Dejosez M, et al. The oral drug nitazoxanide restricts SARS-CoV-2 infection and attenuates disease pathogenesis in Syrian hamsters. Biorxiv : the Preprint Server For Biology. PMID 35169796 DOI: 10.1101/2022.02.08.479634 |
0.3 |
|
2022 |
Escalera A, Gonzalez-Reiche AS, Aslam S, Mena I, Laporte M, Pearl RL, Fossati A, Rathnasinghe R, Alshammary H, van de Guchte A, Farrugia K, Qin Y, Bouhaddou M, Kehrer T, Zuliani-Alvarez L, et al. Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission. Cell Host & Microbe. PMID 35150638 DOI: 10.1016/j.chom.2022.01.006 |
0.305 |
|
2022 |
Gaudreault NN, Cool K, Trujillo JD, Morozov I, Meekins DA, McDowell C, Bold D, Carossino M, Balaraman V, Mitzel D, Kwon T, Madden DW, Artiaga BL, Pogranichniy RM, Roman-Sosa G, et al. Susceptibility of sheep to experimental co-infection with the ancestral lineage of SARS-CoV-2 and its alpha variant. Emerging Microbes & Infections. 1-27. PMID 35105272 DOI: 10.1080/22221751.2022.2037397 |
0.315 |
|
2022 |
Bracci N, de la Fuente C, Saleem S, Pinkham C, Narayanan A, García-Sastre A, Balaraman V, Richt JA, Wilson W, Kehn-Hall K. Rift Valley fever virus Gn V5-epitope tagged virus enables identification of UBR4 as a Gn interacting protein that facilitates Rift Valley fever virus production. Virology. 567: 65-76. PMID 35032865 DOI: 10.1016/j.virol.2021.12.010 |
0.446 |
|
2021 |
Thorne LG, Bouhaddou M, Reuschl AK, Zuliani-Alvarez L, Polacco B, Pelin A, Batra J, Whelan MVX, Hosmillo M, Fossati A, Ragazzini R, Jungreis I, Ummadi M, Rojc A, Turner J, et al. Evolution of enhanced innate immune evasion by SARS-CoV-2. Nature. PMID 34942634 DOI: 10.1038/s41586-021-04352-y |
0.346 |
|
2021 |
Guthmiller JJ, Han J, Utset HA, Li L, Lan LY, Henry C, Stamper CT, McMahon M, O'Dell G, Fernández-Quintero ML, Freyn AW, Amanat F, Stovicek O, Gentles L, Richey ST, et al. Broadly neutralizing antibodies target a hemagglutinin anchor epitope. Nature. PMID 34942633 DOI: 10.1038/s41586-021-04356-8 |
0.338 |
|
2021 |
Rathnasinghe R, Salvatore M, Zheng H, Jangra S, Kehrer T, Mena I, Schotsaert M, Muster T, Palese P, García-Sastre A. Interferon mediated prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine lacking non-structural protein 1. Scientific Reports. 11: 22164. PMID 34773048 DOI: 10.1038/s41598-021-01780-8 |
0.739 |
|
2021 |
Liu Y, Strohmeier S, González-Domínguez I, Tan J, Simon V, Krammer F, García-Sastre A, Palese P, Sun W. Mosaic Hemagglutinin-Based Whole Inactivated Virus Vaccines Induce Broad Protection Against Influenza B Virus Challenge in Mice. Frontiers in Immunology. 12: 746447. PMID 34603333 DOI: 10.3389/fimmu.2021.746447 |
0.334 |
|
2021 |
Martin-Sancho L, Tripathi S, Rodriguez-Frandsen A, Pache L, Sanchez-Aparicio M, McGregor MJ, Haas KM, Swaney DL, Nguyen TT, Mamede JI, Churas C, Pratt D, Rosenthal SB, Riva L, Nguyen C, et al. Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy. Nature Microbiology. PMID 34556855 DOI: 10.1038/s41564-021-00964-2 |
0.425 |
|
2021 |
Lee S, Yu Y, Trimpert J, Benthani F, Mairhofer M, Richter-Pechanska P, Wyler E, Belenki D, Kaltenbrunner S, Pammer M, Kausche L, Firsching TC, Dietert K, Schotsaert M, Martínez-Romero C, et al. Virus-induced senescence is driver and therapeutic target in COVID-19. Nature. PMID 34517409 DOI: 10.1038/s41586-021-03995-1 |
0.334 |
|
2021 |
Riera E, Pérez-Núñez D, García-Belmonte R, Miorin L, García-Sastre A, Revilla Y. African Swine Fever Virus Induces STAT1 and STAT2 Degradation to Counteract IFN-I Signaling. Frontiers in Microbiology. 12: 722952. PMID 34512601 DOI: 10.3389/fmicb.2021.722952 |
0.453 |
|
2021 |
Rathnasinghe R, Salvatore M, Zheng H, Jangra S, Kehrer T, Mena I, Schotsaert M, Muster T, Palese P, Garcia-Sastre A. Prophylactic Protection Against Respiratory Viruses Conferred by a Prototype Live Attenuated Influenza Virus Vaccine. Research Square. PMID 34401874 DOI: 10.21203/rs.3.rs-668116/v1 |
0.735 |
|
2021 |
White K, Esparza M, Liang J, Bhat P, Naidoo J, McGovern BL, Williams MAP, Alabi BR, Shay J, Niederstrasser H, Posner B, García-Sastre A, Ready J, Fontoura BMA. Aryl Sulfonamide Inhibits Entry and Replication of Diverse Influenza Viruses via the Hemagglutinin Protein. Journal of Medicinal Chemistry. PMID 34260245 DOI: 10.1021/acs.jmedchem.1c00304 |
0.406 |
|
2021 |
Telenti A, Arvin A, Corey L, Corti D, Diamond MS, García-Sastre A, Garry RF, Holmes EC, Pang P, Virgin HW. After the pandemic: perspectives on the future trajectory of COVID-19. Nature. PMID 34237771 DOI: 10.1038/s41586-021-03792-w |
0.329 |
|
2021 |
Vidal S, Sánchez-Aparicio M, Seoane R, El Motiam A, Nelson EV, Bouzaher YH, Baz-Martínez M, García-Dorival I, Gonzalo S, Vázquez E, Vidal A, Muñoz-Fontela C, García-Sastre A, Rivas C. Expression of the Ebola Virus VP24 Protein Compromises the Integrity of the Nuclear Envelope and Induces a Laminopathy-Like Cellular Phenotype. Mbio. e0097221. PMID 34225493 DOI: 10.1128/mBio.00972-21 |
0.353 |
|
2021 |
Bohannon CD, Ende Z, Cao W, Mboko WP, Ranjan P, Kumar A, Mishina M, Amoah S, Gangappa S, Mittal SK, Lovell JF, García-Sastre A, Pfeifer BA, Davidson BA, Knight P, et al. Influenza Virus Infects and Depletes Activated Adaptive Immune Responders. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2100693. PMID 34189857 DOI: 10.1002/advs.202100693 |
0.331 |
|
2021 |
Kehrer T, García-Sastre A, Miorin L. Control of Innate Immune Activation by Severe Acute Respiratory Syndrome Coronavirus 2 and Other Coronaviruses. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 41: 205-219. PMID 34161170 DOI: 10.1089/jir.2021.0060 |
0.313 |
|
2021 |
Silvas JA, Morales Vasquez D, Park JG, Chiem K, Allué-Guardia A, Garcia-Vilanova A, Platt RN, Miorin L, Kehrer T, Cupic A, Gonzalez-Reiche AS, van Bakel H, García-Sastre A, Anderson T, Torrelles JB, et al. Contribution of SARS-CoV-2 accessory proteins to viral pathogenicity in K18 hACE2 transgenic mice. Journal of Virology. JVI0040221. PMID 34133899 DOI: 10.1128/JVI.00402-21 |
0.362 |
|
2021 |
Dai M, Du W, Martínez-Romero C, Leenders T, Wennekes T, Rimmelzwaan GF, van Kuppeveld FJM, Fouchier RAM, Garcia-Sastre A, de Vries E, de Haan CAM. Analysis of the Evolution of Pandemic Influenza A(H1N1) Virus Neuraminidase Reveals Entanglement of Different Phenotypic Characteristics. Mbio. 12. PMID 33975931 DOI: 10.1128/mBio.00287-21 |
0.35 |
|
2021 |
Rathnasinghe R, Salvatore M, Zheng H, Jangra S, Kehrer T, Mena I, Schotsaert M, Muster T, Palese P, García-Sastre A. Prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine. Biorxiv : the Preprint Server For Biology. PMID 33948589 DOI: 10.1101/2021.04.28.441797 |
0.735 |
|
2021 |
Martin-Sancho L, Lewinski MK, Pache L, Stoneham CA, Yin X, Becker ME, Pratt D, Churas C, Rosenthal SB, Liu S, Weston S, De Jesus PD, O'Neill AM, Gounder AP, Nguyen C, et al. Functional landscape of SARS-CoV-2 cellular restriction. Molecular Cell. PMID 33930332 DOI: 10.1016/j.molcel.2021.04.008 |
0.452 |
|
2021 |
Nogales A, Schotsaert M, Rathnasinghe R, DeDiego ML, García-Sastre A, Martinez-Sobrido L. Replication-Competent ΔNS1 Influenza A Viruses Expressing Reporter Genes. Viruses. 13. PMID 33920517 DOI: 10.3390/v13040698 |
0.454 |
|
2021 |
Lanz C, Schotsaert M, Magnus C, Karakus U, Hunziker A, Sempere Borau M, Martínez-Romero C, Spieler EE, Günther SC, Moritz E, Hale BG, Trkola A, García-Sastre A, Stertz S. IFITM3 incorporation sensitizes influenza A virus to antibody-mediated neutralization. The Journal of Experimental Medicine. 218. PMID 33882122 DOI: 10.1084/jem.20200303 |
0.415 |
|
2021 |
Gaudreault NN, Carossino M, Morozov I, Trujillo JD, Meekins DA, Madden DW, Cool K, Artiaga BL, McDowell C, Bold D, Balaraman V, Kwon T, Ma W, Henningson J, Wilson DW, et al. Experimental re-infected cats do not transmit SARS-CoV-2. Emerging Microbes & Infections. 1-38. PMID 33704016 DOI: 10.1080/22221751.2021.1902753 |
0.314 |
|
2021 |
Reuschl AK, Thorne L, Zuliani Alvarez L, Bouhaddou M, Obernier K, Soucheray M, Turner J, Fabius J, Nguyen GT, Swaney D, Rosales R, White KM, Aviles P, Kirby IT, Melnyk JE, ... ... Garcia-Sastre A, et al. Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant. Biorxiv : the Preprint Server For Biology. PMID 33501437 DOI: 10.1101/2021.01.24.427991 |
0.308 |
|
2021 |
White KM, Rosales R, Yildiz S, Kehrer T, Miorin L, Moreno E, Jangra S, Uccellini MB, Rathnasinghe R, Coughlan L, Martinez-Romero C, Batra J, Rojc A, Bouhaddou M, Fabius JM, et al. Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A. Science (New York, N.Y.). PMID 33495306 DOI: 10.1126/science.abf4058 |
0.33 |
|
2021 |
Liu WC, Nachbagauer R, Stadlbauer D, Strohmeier S, Solórzano A, Berlanda-Scorza F, Innis BL, García-Sastre A, Palese P, Krammer F, Albrecht RA. Chimeric Hemagglutinin-Based Live-Attenuated Vaccines Confer Durable Protective Immunity against Influenza A Viruses in a Preclinical Ferret Model. Vaccines. 9. PMID 33440898 DOI: 10.3390/vaccines9010040 |
0.344 |
|
2021 |
Yin X, Riva L, Pu Y, Martin-Sancho L, Kanamune J, Yamamoto Y, Sakai K, Gotoh S, Miorin L, De Jesus PD, Yang CC, Herbert KM, Yoh S, Hultquist JF, García-Sastre A, et al. MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells. Cell Reports. 34: 108628. PMID 33440148 DOI: 10.1016/j.celrep.2020.108628 |
0.371 |
|
2021 |
Muñoz-Moreno R, Martínez-Romero C, García-Sastre A. Induction and Evasion of Type-I Interferon Responses during Influenza A Virus Infection. Cold Spring Harbor Perspectives in Medicine. 11. PMID 32661015 DOI: 10.1101/cshperspect.a038414 |
0.428 |
|
2020 |
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Thamamongood T, Aebischer A, Wagner V, Chang MW, Elling R, Benner C, García-Sastre A, Kochs G, Beer M, Schwemmle M. A genome-wide CRISPR-Cas9 screen reveals the requirement of host cell sulfation for Schmallenberg virus infection. Journal of Virology. PMID 32522852 DOI: 10.1128/Jvi.00752-20 |
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Bangaru S, Lang S, Schotsaert M, Vanderven HA, Zhu X, Kose N, Bombardi R, Finn JA, Kent SJ, Gilchuk P, Gilchuk I, Turner HL, García-Sastre A, Li S, Ward AB, et al. A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface. Cell. 177: 1136-1152.e18. PMID 31100268 DOI: 10.1016/J.Cell.2019.04.011 |
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Bailey MJ, Broecker F, Freyn A, Choi A, Brown JA, Fedorova N, Simon V, Lim JK, Evans MJ, García-Sastre A, Palese P, Tan GS. Human monoclonal antibodies potently neutralize Zika virus and select for escape mutations on the lateral ridge of the envelope protein. Journal of Virology. PMID 31043537 DOI: 10.1128/Jvi.00405-19 |
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Miorin L, Laurent-Rolle M, Pisanelli G, Co PH, Albrecht RA, García-Sastre A, Morrison J. Host-specific NS5 ubiquitination determines yellow fever virus tropism. Journal of Virology. PMID 31043530 DOI: 10.1128/Jvi.00151-19 |
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Choi A, Bouzya B, Cortés Franco KD, Stadlbauer D, Rajabhathor A, Rouxel RN, Mainil R, Van der Wielen M, Palese P, García-Sastre A, Innis BL, Krammer F, Schotsaert M, Mallett CP, Nachbagauer R. Chimeric Hemagglutinin-Based Influenza Virus Vaccines Induce Protective Stalk-Specific Humoral Immunity and Cellular Responses in Mice. Immunohorizons. 3: 133-148. PMID 31032479 DOI: 10.4049/immunohorizons.1900022 |
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Arunkumar GA, Ioannou A, Wohlbold TJ, Meade P, Aslam S, Amanat F, Ayllon J, García-Sastre A, Krammer F. Broadly cross-reactive, non-neutralizing antibodies against the influenza B virus hemagglutinin demonstrate effector function dependent protection against lethal viral challenge in mice. Journal of Virology. PMID 30626682 DOI: 10.1128/JVI.01696-18 |
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Bolte H, Rosu ME, Hagelauer E, García-Sastre A, Schwemmle M. Packaging of the Influenza Virus Genome Is Governed by a Plastic Network of RNA- and Nucleoprotein-Mediated Interactions. Journal of Virology. 93. PMID 30463968 DOI: 10.1128/JVI.01861-18 |
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Uccellini MB, García-Sastre A. ISRE-Reporter Mouse Reveals High Basal and Induced Type I IFN Responses in Inflammatory Monocytes. Cell Reports. 25: 2784-2796.e3. PMID 30517866 DOI: 10.1016/J.Celrep.2018.11.030 |
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Hancock AS, Stairiker CJ, Boesteanu AC, Monzón-Casanova E, Lukasiak S, Mueller YM, Stubbs AP, Garcia-Sastre A, Turner M, Katsikis PD. Transcriptome analysis of infected and bystander type 2 alveolar epithelial cells during influenza A virus infection reveals Wnt pathway downregulation. Journal of Virology. PMID 30111569 DOI: 10.1128/Jvi.01325-18 |
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White KM, Abreu P, Wang H, De Jesus PD, Manicassamy B, García-Sastre A, Chanda SK, DeVita RJ, Shaw ML. Broad Spectrum Inhibitor of Influenza A and B Viruses Targeting the Viral Nucleoprotein. Acs Infectious Diseases. PMID 29268608 DOI: 10.1021/Acsinfecdis.7B00120 |
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Nachbagauer R, Liu WC, Choi A, Wohlbold TJ, Atlas T, Rajendran M, Solórzano A, Berlanda-Scorza F, García-Sastre A, Palese P, Albrecht RA, Krammer F. A universal influenza virus vaccine candidate confers protection against pandemic H1N1 infection in preclinical ferret studies. Npj Vaccines. 2: 26. PMID 29263881 DOI: 10.1038/s41541-017-0026-4 |
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2017 |
Hartmann BM, Albrecht RA, Zaslavsky E, Nudelman G, Pincas H, Marjanovic N, Schotsaert M, Martínez-Romero C, Fenutria R, Ingram JP, Ramos I, Fernandez-Sesma A, Balachandran S, García-Sastre A, Sealfon SC. Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death. Nature Communications. 8: 1931. PMID 29203926 DOI: 10.1038/S41467-017-02035-9 |
0.327 |
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2017 |
Doğanay S, Lee MY, Baum A, Peh J, Hwang SY, Yoo JY, Hergenrother PJ, García-Sastre A, Myong S, Ha T. Single-cell analysis of early antiviral gene expression reveals a determinant of stochastic IFNB1 expression. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 29098213 DOI: 10.1039/C7Ib00146K |
0.749 |
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2017 |
Martín-Vicente M, Medrano LM, Resino S, García-Sastre A, Martínez I. TRIM25 in the Regulation of the Antiviral Innate Immunity. Frontiers in Immunology. 8: 1187. PMID 29018447 DOI: 10.3389/fimmu.2017.01187 |
0.385 |
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2017 |
Kuss-Duerkop SK, Wang J, Mena I, White K, Metreveli G, Sakthivel R, Mata MA, Muñoz-Moreno R, Chen X, Krammer F, Diamond MS, Chen ZJ, García-Sastre A, Fontoura BMA. Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication. Plos Pathogens. 13: e1006635. PMID 28953980 DOI: 10.1371/Journal.Ppat.1006635 |
0.494 |
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2017 |
Patzina C, Botting CH, García-Sastre A, Randall RE, Hale BG. Human interactome of the influenza B virus NS1 protein. The Journal of General Virology. 98: 2267-2273. PMID 28869005 DOI: 10.1099/jgv.0.000909 |
0.41 |
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2017 |
Sánchez-Aparicio MT, Garcin D, Rice CM, Kolakofsky D, García-Sastre A, Baum A. Loss of Sendai virus C protein leads to accumulation of RIG-I immunostimulatory defective interfering RNA. The Journal of General Virology. PMID 28631605 DOI: 10.1099/Jgv.0.000815 |
0.775 |
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2017 |
Miorin L, Maestre AM, Fernandez-Sesma A, García-Sastre A. Antagonism of type I interferon by flaviviruses. Biochemical and Biophysical Research Communications. PMID 28576494 DOI: 10.1016/j.bbrc.2017.05.146 |
0.353 |
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2017 |
Luthra P, Aguirre S, Yen BC, Pietzsch CA, Sanchez-Aparicio MT, Tigabu B, Morlock LK, García-Sastre A, Leung DW, Williams NS, Fernandez-Sesma A, Bukreyev A, Basler CF. Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion. Mbio. 8. PMID 28377530 DOI: 10.1128/Mbio.00368-17 |
0.48 |
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2017 |
Bardina SV, Bunduc P, Tripathi S, Duehr J, Frere JJ, Brown JA, Nachbagauer R, Foster GA, Krysztof D, Tortorella D, Stramer SL, García-Sastre A, Krammer F, Lim JK. Enhancement of Zika virus pathogenesis by preexisting antiflavivirus immunity. Science (New York, N.Y.). PMID 28360135 DOI: 10.1126/Science.Aal4365 |
0.348 |
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2017 |
Leyva-Grado VH, Ermler ME, Schotsaert M, Gonzalez MG, Gillespie V, Lim JK, García-Sastre A. Contribution of the Purinergic Receptor P2X7 to Development of Lung Immunopathology during Influenza Virus Infection. Mbio. 8. PMID 28351919 DOI: 10.1128/mBio.00229-17 |
0.394 |
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2017 |
Aguirre S, Luthra P, Sanchez-Aparicio MT, Maestre AM, Patel J, Lamothe F, Fredericks AC, Tripathi S, Zhu T, Pintado-Silva J, Webb LG, Bernal-Rubio D, Solovyov A, Greenbaum B, Simon V, et al. Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection. Nature Microbiology. 2: 17037. PMID 28346446 DOI: 10.1038/Nmicrobiol.2017.37 |
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2017 |
Tripathi S, Balasubramaniam VR, Brown JA, Mena I, Grant A, Bardina SV, Maringer K, Schwarz MC, Maestre AM, Sourisseau M, Albrecht RA, Krammer F, Evans MJ, Fernandez-Sesma A, Lim JK, et al. A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses. Plos Pathogens. 13: e1006258. PMID 28278235 DOI: 10.1371/journal.ppat.1006258 |
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2017 |
Soonthornvacharin S, Rodriguez-Frandsen A, Zhou Y, Galvez F, Huffmaster NJ, Tripathi S, Balasubramaniam VR, Inoue A, de Castro E, Moulton H, Stein DA, Sánchez-Aparicio MT, De Jesus PD, Nguyen Q, König R, et al. Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation. Nature Microbiology. 2: 17022. PMID 28248290 DOI: 10.1038/Nmicrobiol.2017.22 |
0.368 |
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2017 |
Nachbagauer R, Choi A, Hirsh A, Margine I, Iida S, Barrera A, Ferres M, Albrecht RA, García-Sastre A, Bouvier NM, Ito K, Medina RA, Palese P, Krammer F. Defining the antibody cross-reactome directed against the influenza virus surface glycoproteins. Nature Immunology. PMID 28192418 DOI: 10.1038/Ni.3684 |
0.377 |
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2017 |
Kumar A, Kim JH, Ranjan P, Metcalfe MG, Cao W, Mishina M, Gangappa S, Guo Z, Boyden ES, Zaki S, York I, García-Sastre A, Shaw M, Sambhara S. Influenza virus exploits tunneling nanotubes for cell-to-cell spread. Scientific Reports. 7: 40360. PMID 28059146 DOI: 10.1038/Srep40360 |
0.417 |
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2016 |
Eduardo-Correia B, Martínez-Romero C, García-Sastre A, Guerra S. Correction for Eduardo-Correia et al., ISG15 Is Counteracted by Vaccinia Virus E3 Protein and Controls the Proinflammatory Response against Viral Infection. Journal of Virology. 90: 11280. PMID 27895186 DOI: 10.1128/JVI.01920-16 |
0.333 |
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2016 |
Moreira ÉA, Weber A, Bolte H, Kolesnikova L, Giese S, Lakdawala S, Beer M, Zimmer G, García-Sastre A, Schwemmle M, Juozapaitis M. A conserved influenza A virus nucleoprotein code controls specific viral genome packaging. Nature Communications. 7: 12861. PMID 27650413 DOI: 10.1038/ncomms12861 |
0.312 |
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2016 |
Coloma J, Jain R, Rajashankar KR, García-Sastre A, Aggarwal AK. Structures of NS5 Methyltransferase from Zika Virus. Cell Reports. PMID 27633330 DOI: 10.1016/J.Celrep.2016.08.091 |
0.308 |
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2016 |
Mor A, White A, Zhang K, Thompson M, Esparza M, Muñoz-Moreno R, Koide K, Lynch KW, García-Sastre A, Fontoura BM. Influenza virus mRNA trafficking through host nuclear speckles. Nature Microbiology. 1: 16069. PMID 27572970 DOI: 10.1038/Nmicrobiol.2016.69 |
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2016 |
Jain R, Coloma J, García-Sastre A, Aggarwal AK. Structure of the NS3 helicase from Zika virus. Nature Structural & Molecular Biology. PMID 27399257 DOI: 10.1038/Nsmb.3258 |
0.329 |
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2016 |
DiPiazza A, Richards K, Batarse F, Lockard L, Zeng H, García-Sastre A, Albrecht RA, Sant AJ. Flow Cytometric and Cytokine ELISpot Approaches to Characterize the Cell-mediated Immune Response in Ferrets Following Influenza Virus Infection. Journal of Virology. PMID 27356897 DOI: 10.1128/Jvi.01001-16 |
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2016 |
Mena I, Nelson MI, Quezada-Monroy F, Dutta J, Cortes-Fernández R, Lara-Puente JH, Castro-Peralta F, Cunha LF, Trovão NS, Lozano-Dubernard B, Rambaut A, van Bakel H, García-Sastre A. Origins of the 2009 H1N1 influenza pandemic in swine in Mexico. Elife. 5. PMID 27350259 DOI: 10.7554/Elife.16777 |
0.369 |
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2016 |
Grant A, Ponia SS, Tripathi S, Balasubramaniam V, Miorin L, Sourisseau M, Schwarz MC, Sánchez-Seco MP, Evans MJ, Best SM, García-Sastre A. Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling. Cell Host & Microbe. PMID 27212660 DOI: 10.1016/j.chom.2016.05.009 |
0.5 |
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2016 |
Speer SD, Li Z, Buta S, Payelle-Brogard B, Qian L, Vigant F, Rubino E, Gardner TJ, Wedeking T, Hermann M, Duehr J, Sanal O, Tezcan I, Mansouri N, Tabarsi P, et al. ISG15 deficiency and increased viral resistance in humans but not mice. Nature Communications. 7: 11496. PMID 27193971 DOI: 10.1038/Ncomms11496 |
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2016 |
Schotsaert M, García-Sastre A. A High-Resolution Look at Influenza Virus Antigenic Drift. The Journal of Infectious Diseases. 214: 982. PMID 27190189 DOI: 10.1093/infdis/jiw183 |
0.361 |
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2016 |
Rialdi A, Campisi L, Zhao N, Lagda AC, Pietzsch C, Ho JS, Martinez-Gil L, Fenouil R, Chen X, Edwards M, Metreveli G, Jordan S, Peralta Z, Munoz-Fontela C, Bouvier N, et al. Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation. Science (New York, N.Y.). PMID 27127234 DOI: 10.1126/Science.Aad7993 |
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2016 |
Muñoz-Moreno R, Cuesta-Geijo MÁ, Martínez-Romero C, Barrado-Gil L, Galindo I, García-Sastre A, Alonso C. Antiviral Role of IFITM Proteins in African Swine Fever Virus Infection. Plos One. 11: e0154366. PMID 27116236 DOI: 10.1371/journal.pone.0154366 |
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2016 |
Nagy A, Lee J, Mena I, Henningson J, Li Y, Ma J, Duff M, Li Y, Lang Y, Yang J, Abdallah F, Richt J, Ali A, García-Sastre A, Ma W. Recombinant Newcastle disease virus expressing H9 HA protects chickens against heterologous avian influenza H9N2 virus challenge. Vaccine. PMID 27102817 DOI: 10.1016/J.Vaccine.2016.04.022 |
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2016 |
Thornburg NJ, Zhang H, Bangaru S, Sapparapu G, Kose N, Lampley RM, Bombardi RG, Yu Y, Graham S, Branchizio A, Yoder SM, Rock MT, Creech CB, Edwards KM, Lee D, et al. H7N9 influenza virus neutralizing antibodies that possess few somatic mutations. The Journal of Clinical Investigation. PMID 26950424 DOI: 10.1172/Jci85317 |
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2016 |
Moroz E, Albrecht RA, Aden B, Beeder AB, Yuan J, García-Sastre A, Edlin BR, Salvatore M. Active opioid use does not attenuate the humoral responses to inactivated influenza vaccine. Vaccine. PMID 26859239 DOI: 10.1016/j.vaccine.2016.01.051 |
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2016 |
Heaton NS, Moshkina N, Fenouil R, Gardner TJ, Aguirre S, Shah PS, Zhao N, Manganaro L, Hultquist JF, Noel J, Sachs DH, Hamilton J, Leon PE, Chawdury A, Tripathi S, et al. Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection. Immunity. 44: 46-58. PMID 26789921 DOI: 10.1016/J.Immuni.2015.12.017 |
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2015 |
Nachbagauer R, Miller MS, Hai R, Ryder AB, Rose JK, Palese P, García-Sastre A, Krammer F, Albrecht RA. Hemagglutinin Stalk Immunity Reduces Influenza Virus Replication and Transmission in Ferrets. Journal of Virology. 90: 3268-73. PMID 26719251 DOI: 10.1128/Jvi.02481-15 |
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2015 |
Tripathi S, Garcia-Sastre A. Antiviral innate immunity through the lens of systems biology. Virus Research. PMID 26657882 DOI: 10.1016/j.virusres.2015.11.024 |
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2015 |
Tripathi S, Pohl MO, Zhou Y, Rodriguez-Frandsen A, Wang G, Stein DA, Moulton HM, DeJesus P, Che J, Mulder LC, Yángüez E, Andenmatten D, Pache L, Manicassamy B, Albrecht RA, et al. Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding. Cell Host & Microbe. 18: 723-735. PMID 26651948 DOI: 10.1016/J.Chom.2015.11.002 |
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2015 |
Pisanelli G, Laurent-Rolle M, Manicassamy B, Belicha-Villanueva A, Morrison J, Lozano-Dubernard B, Castro-Peralta F, Iovane G, García-Sastre A. La Piedad Michoacán Mexico Virus V protein antagonizes type I interferon response by binding STAT2 protein and preventing STATs nuclear translocation. Virus Research. PMID 26546155 DOI: 10.1016/J.Virusres.2015.10.027 |
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2015 |
Turkington HL, Juozapaitis M, Kerry PS, Aydillo T, Ayllon J, García-Sastre A, Schwemmle M, Hale BG. Novel Bat Influenza Virus NS1 Proteins Bind Double-Stranded RNA and Antagonize Host Innate Immunity. Journal of Virology. 89: 10696-701. PMID 26246567 DOI: 10.1128/JVI.01430-15 |
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2015 |
Marazzi I, Garcia-Sastre A. Interference of viral effector proteins with chromatin, transcription, and the epigenome. Current Opinion in Microbiology. 26: 123-9. PMID 26232586 DOI: 10.1016/j.mib.2015.06.009 |
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2015 |
Spengler JR, Patel JR, Chakrabarti AK, Zivcec M, García-Sastre A, Spiropoulou CF, Bergeron É. RIG-I mediates an antiviral response to Crimean-Congo hemorrhagic fever virus. Journal of Virology. PMID 26223644 DOI: 10.1128/Jvi.01643-15 |
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2015 |
Hartmann BM, Thakar J, Albrecht RA, Avey S, Zaslavsky E, Marjanovic N, Chikina M, Fribourg M, Hayot F, Schmolke M, Meng H, Wetmur J, García-Sastre A, Kleinstein SH, Sealfon SC. Human Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses. Journal of Virology. 89: 10190-205. PMID 26223639 DOI: 10.1128/Jvi.01523-15 |
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2015 |
Schoggins JW, MacDuff DA, Imanaka N, Gainey MD, Shrestha B, Eitson JL, Mar KB, Richardson RB, Ratushny AV, Litvak V, Dabelic R, Manicassamy B, Aitchison JD, Aderem A, Elliott RM, et al. Corrigendum: Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. Nature. 525: 144. PMID 26153856 DOI: 10.1038/Nature14555 |
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2015 |
Cao W, Mishina M, Ranjan P, De La Cruz JA, Kim JH, Garten R, Kumar A, García-Sastre A, Katz JM, Gangappa S, Sambhara S. A newly emerged swine origin A(H3N2)v influenza virus dampens host antiviral immunity but induces potent inflammasome activation. The Journal of Infectious Diseases. PMID 26068782 DOI: 10.1093/Infdis/Jiv330 |
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2015 |
White KM, De Jesus P, Chen Z, Abreu P, Barile E, Mak PA, Anderson P, Nguyen QT, Inoue A, Stertz S, Koenig R, Pellecchia M, Palese P, Kuhen K, García-Sastre A, et al. A Potent Anti-influenza Compound Blocks Fusion through Stabilization of the Prefusion Conformation of the Hemagglutinin Protein. Acs Infectious Diseases. 1: 98-109. PMID 25984567 DOI: 10.1021/Id500022H |
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2015 |
Nistal-Villán E, Rodríguez-García E, Di Scala M, Ferrero-Laborda R, Olagüe C, Vales Á, Carte-Abad B, Crespo I, García-Sastre A, Prieto J, Larrea E, González-Aseguinolaza G. A RIG-I 2CARD-MAVS200 Chimeric Protein Reconstitutes IFN-β Induction and Antiviral Response in Models Deficient in Type I IFN Response. Journal of Innate Immunity. 7: 466-81. PMID 25966783 DOI: 10.1159/000375262 |
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2015 |
Liu Q, Mena I, Ma J, Bawa B, Krammer F, Lyoo YS, Lang Y, Morozov I, Mahardika GN, Ma W, García-Sastre A, Richt JA. Newcastle Disease Virus-Vectored H7 and H5 Live Vaccines Protect Chickens from Challenge with H7N9 or H5N1 Avian Influenza Viruses. Journal of Virology. 89: 7401-8. PMID 25926639 DOI: 10.1128/JVI.00031-15 |
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2015 |
Ciancanelli MJ, Huang SX, Luthra P, Garner H, Itan Y, Volpi S, Lafaille FG, Trouillet C, Schmolke M, Albrecht RA, Israelsson E, Lim HK, Casadio M, Hermesh T, Lorenzo L, et al. Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency. Science (New York, N.Y.). 348: 448-53. PMID 25814066 DOI: 10.1126/Science.Aaa1578 |
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2015 |
Cuadrado-Castano S, Ayllon J, Mansour M, de la Iglesia-Vicente J, Jordan S, Tripathi S, García-Sastre A, Villar E. Enhancement of the proapoptotic properties of newcastle disease virus promotes tumor remission in syngeneic murine cancer models. Molecular Cancer Therapeutics. 14: 1247-58. PMID 25761895 DOI: 10.1158/1535-7163.MCT-14-0913 |
0.325 |
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2015 |
Weber M, Sediri H, Felgenhauer U, Binzen I, Bänfer S, Jacob R, Brunotte L, García-Sastre A, Schmid-Burgk JL, Schmidt T, Hornung V, Kochs G, Schwemmle M, Klenk HD, Weber F. Influenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I. Cell Host & Microbe. 17: 309-19. PMID 25704008 DOI: 10.1016/j.chom.2015.01.005 |
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2015 |
Henry Dunand CJ, Leon PE, Kaur K, Tan GS, Zheng NY, Andrews S, Huang M, Qu X, Huang Y, Salgado-Ferrer M, Ho IY, Taylor W, Hai R, Wrammert J, Ahmed R, et al. Preexisting human antibodies neutralize recently emerged H7N9 influenza strains. The Journal of Clinical Investigation. 125: 1255-68. PMID 25689254 DOI: 10.1172/Jci74374 |
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2015 |
Riegger D, Hai R, Dornfeld D, Mänz B, Leyva-Grado V, Sánchez-Aparicio MT, Albrecht RA, Palese P, Haller O, Schwemmle M, García-Sastre A, Kochs G, Schmolke M. The nucleoprotein of newly emerged H7N9 influenza A virus harbors a unique motif conferring resistance to antiviral human MxA. Journal of Virology. 89: 2241-52. PMID 25505067 DOI: 10.1128/Jvi.02406-14 |
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2015 |
He XS, Holmes TH, Sanyal M, Albrecht RA, García-Sastre A, Dekker CL, Davis MM, Greenberg HB. Distinct patterns of B-cell activation and priming by natural influenza virus infection versus inactivated influenza vaccination. The Journal of Infectious Diseases. 211: 1051-9. PMID 25336731 DOI: 10.1093/Infdis/Jiu580 |
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2015 |
Ayllon J, García-Sastre A. The NS1 protein: a multitasking virulence factor. Current Topics in Microbiology and Immunology. 386: 73-107. PMID 25007846 DOI: 10.1007/82_2014_400 |
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2014 |
Varble A, Albrecht RA, Backes S, Crumiller M, Bouvier NM, Sachs D, García-Sastre A, tenOever BR. Influenza A virus transmission bottlenecks are defined by infection route and recipient host. Cell Host & Microbe. 16: 691-700. PMID 25456074 DOI: 10.1016/J.Chom.2014.09.020 |
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2014 |
Macleod JML, Marmor H, García-Sastre A, Frias-Staheli N. Mapping of the interaction domains of the Crimean-Congo hemorrhagic fever virus nucleocapsid protein. The Journal of General Virology. 96: 524-537. PMID 25389186 DOI: 10.1099/vir.0.071332-0 |
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2014 |
Rajsbaum R, García-Sastre A. Virology. Unanchored ubiquitin in virus uncoating. Science (New York, N.Y.). 346: 427-8. PMID 25342790 DOI: 10.1126/science.1261509 |
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2014 |
Skinner JA, Zurawski SM, Sugimoto C, Vinet-Oliphant H, Vinod P, Xue Y, Russell-Lodrigue K, Albrecht RA, García-Sastre A, Salazar AM, Roy CJ, Kuroda MJ, Oh S, Zurawski G. Immunologic characterization of a rhesus macaque H1N1 challenge model for candidate influenza virus vaccine assessment. Clinical and Vaccine Immunology : Cvi. 21: 1668-80. PMID 25298110 DOI: 10.1128/Cvi.00547-14 |
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2014 |
Laurent-Rolle M, Morrison J, Rajsbaum R, Macleod JM, Pisanelli G, Pham A, Ayllon J, Miorin L, Martínez-Romero C, tenOever BR, García-Sastre A. The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferon. Cell Host & Microbe. 16: 314-27. PMID 25211074 DOI: 10.1016/J.Chom.2014.07.015 |
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2014 |
Ayllon J, Domingues P, Rajsbaum R, Miorin L, Schmolke M, Hale BG, García-Sastre A. A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence. Journal of Virology. 88: 12146-51. PMID 25078692 DOI: 10.1128/JVI.01567-14 |
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2014 |
Juozapaitis M, Aguiar Moreira É, Mena I, Giese S, Riegger D, Pohlmann A, Höper D, Zimmer G, Beer M, García-Sastre A, Schwemmle M. An infectious bat-derived chimeric influenza virus harbouring the entry machinery of an influenza A virus. Nature Communications. 5: 4448. PMID 25055345 DOI: 10.1038/ncomms5448 |
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2014 |
Ovsyannikova IG, White SJ, Albrecht RA, García-Sastre A, Poland GA. Turkey versus guinea pig red blood cells: Hemagglutination differences alter hemagglutination inhibition responses against influenza A/H1N1 Viral Immunology. 27: 174-178. PMID 24787023 DOI: 10.1089/vim.2013.0111 |
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2014 |
Morrison J, García-Sastre A. STAT2 signaling and dengue virus infection. Jak-Stat. 3: e27715. PMID 24778924 DOI: 10.4161/jkst.27715 |
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2014 |
Runge S, Sparrer KM, Lässig C, Hembach K, Baum A, García-Sastre A, Söding J, Conzelmann KK, Hopfner KP. In vivo ligands of MDA5 and RIG-I in measles virus-infected cells. Plos Pathogens. 10: e1004081. PMID 24743923 DOI: 10.1371/journal.ppat.1004081 |
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2014 |
Metreveli G, Gao Q, Mena I, Schmolke M, Berg M, Albrecht RA, García-Sastre A. The origin of the PB1 segment of swine influenza A virus subtype H1N2 determines viral pathogenicity in mice. Virus Research. 188: 97-102. PMID 24726997 DOI: 10.1016/j.virusres.2014.03.023 |
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2014 |
Ma W, Liu Q, Qiao C, del Real G, García-Sastre A, Webby RJ, Richt JA. North American triple reassortant and Eurasian H1N1 swine influenza viruses do not readily reassort to generate a 2009 pandemic H1N1-like virus. Mbio. 5: e00919-13. PMID 24618255 DOI: 10.1128/Mbio.00919-13 |
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2014 |
Patel JR, García-Sastre A. Three-stranded antiviral attack. Elife. 3: e02369. PMID 24596154 DOI: 10.7554/Elife.02369 |
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2014 |
García-Sastre A, Schmolke M. Avian influenza A H10N8--a virus on the verge? Lancet (London, England). 383: 676-7. PMID 24508318 DOI: 10.1016/S0140-6736(14)60163-X |
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2014 |
Santiago FW, Covaleda LM, Sanchez-Aparicio MT, Silvas JA, Diaz-Vizarreta AC, Patel JR, Popov V, Yu XJ, García-Sastre A, Aguilar PV. Hijacking of RIG-I signaling proteins into virus-induced cytoplasmic structures correlates with the inhibition of type I interferon responses. Journal of Virology. 88: 4572-85. PMID 24478431 DOI: 10.1128/Jvi.03021-13 |
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2014 |
Krammer F, Hai R, Yondola M, Tan GS, Leyva-Grado VH, Ryder AB, Miller MS, Rose JK, Palese P, García-Sastre A, Albrecht RA. Assessment of influenza virus hemagglutinin stalk-based immunity in ferrets. Journal of Virology. 88: 3432-42. PMID 24403585 DOI: 10.1128/Jvi.03004-13 |
0.367 |
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2014 |
Klausberger M, Wilde M, Palmberger D, Hai R, Albrecht RA, Margine I, Hirsh A, García-Sastre A, Grabherr R, Krammer F. One-shot vaccination with an insect cell-derived low-dose influenza A H7 virus-like particle preparation protects mice against H7N9 challenge. Vaccine. 32: 355-62. PMID 24262313 DOI: 10.1016/J.Vaccine.2013.11.036 |
0.339 |
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2014 |
Eduardo-Correia B, Martínez-Romero C, García-Sastre A, Guerra S. ISG15 is counteracted by vaccinia virus E3 protein and controls the proinflammatory response against viral infection. Journal of Virology. 88: 2312-8. PMID 24257616 DOI: 10.1128/JVI.03293-13 |
0.487 |
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2013 |
Boyce WM, Mena I, Yochem PK, Gulland FM, García-Sastre A, Moreno N, Perez DR, Gonzalez-Reiche AS, Stewart BS. Influenza A(H1N1)pdm09 virus infection in marine mammals in California. Emerging Microbes & Infections. 2: e40. PMID 26038474 DOI: 10.1038/emi.2013.40 |
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|
2013 |
Rajsbaum R, García-Sastre A, Versteeg GA. TRIMmunity: the roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity. Journal of Molecular Biology. 426: 1265-84. PMID 24333484 DOI: 10.1016/j.jmb.2013.12.005 |
0.322 |
|
2013 |
Hai R, Schmolke M, Leyva-Grado VH, Thangavel RR, Margine I, Jaffe EL, Krammer F, Solórzano A, García-Sastre A, Palese P, Bouvier NM. Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility. Nature Communications. 4: 2854. PMID 24326875 DOI: 10.1038/Ncomms3854 |
0.373 |
|
2013 |
Sanyal S, Ashour J, Maruyama T, Altenburg AF, Cragnolini JJ, Bilate A, Avalos AM, Kundrat L, García-Sastre A, Ploegh HL. Type I interferon imposes a TSG101/ISG15 checkpoint at the Golgi for glycoprotein trafficking during influenza virus infection. Cell Host & Microbe. 14: 510-21. PMID 24237697 DOI: 10.1016/J.Chom.2013.10.011 |
0.826 |
|
2013 |
Ayllon J, García-Sastre A, Martínez-Sobrido L. Rescue of recombinant Newcastle disease virus from cDNA. Journal of Visualized Experiments : Jove. PMID 24145366 DOI: 10.3791/50830 |
0.399 |
|
2013 |
de Vries RP, de Vries E, Martínez-Romero C, McBride R, van Kuppeveld FJ, Rottier PJ, García-Sastre A, Paulson JC, de Haan CA. Evolution of the hemagglutinin protein of the new pandemic H1N1 influenza virus: maintaining optimal receptor binding by compensatory substitutions. Journal of Virology. 87: 13868-77. PMID 24109242 DOI: 10.1128/Jvi.01955-13 |
0.708 |
|
2013 |
Ramos I, Krammer F, Hai R, Aguilera D, Bernal-Rubio D, Steel J, García-Sastre A, Fernandez-Sesma A. H7N9 influenza viruses interact preferentially with α2,3-linked sialic acids and bind weakly to α2,6-linked sialic acids. The Journal of General Virology. 94: 2417-23. PMID 23950563 DOI: 10.1099/Vir.0.056184-0 |
0.338 |
|
2013 |
Rajsbaum R, García-Sastre A. Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways. Trends in Microbiology. 21: 421-9. PMID 23850008 DOI: 10.1016/j.tim.2013.06.006 |
0.443 |
|
2013 |
Tsai PL, Chiou NT, Kuss S, García-Sastre A, Lynch KW, Fontoura BM. Cellular RNA binding proteins NS1-BP and hnRNP K regulate influenza A virus RNA splicing. Plos Pathogens. 9: e1003460. PMID 23825951 DOI: 10.1371/Journal.Ppat.1003460 |
0.302 |
|
2013 |
Thakar J, Schmid S, Duke JL, García-Sastre A, Kleinstein SH. Overcoming NS1-mediated immune antagonism involves both interferon-dependent and independent mechanisms. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 33: 700-8. PMID 23772952 DOI: 10.1089/Jir.2012.0113 |
0.398 |
|
2013 |
Baker SF, Guo H, Albrecht RA, García-Sastre A, Topham DJ, Martínez-Sobrido L. Protection against lethal influenza with a viral mimic. Journal of Virology. 87: 8591-605. PMID 23720727 DOI: 10.1128/JVI.01081-13 |
0.384 |
|
2013 |
Goff PH, Krammer F, Hai R, Seibert CW, Margine I, García-Sastre A, Palese P. Induction of cross-reactive antibodies to novel H7N9 influenza virus by recombinant Newcastle disease virus expressing a North American lineage H7 subtype hemagglutinin. Journal of Virology. 87: 8235-40. PMID 23698299 DOI: 10.1128/Jvi.01085-13 |
0.375 |
|
2013 |
Seibert CW, Rahmat S, Krause JC, Eggink D, Albrecht RA, Goff PH, Krammer F, Duty JA, Bouvier NM, García-Sastre A, Palese P. Recombinant IgA is sufficient to prevent influenza virus transmission in guinea pigs. Journal of Virology. 87: 7793-804. PMID 23698296 DOI: 10.1128/Jvi.00979-13 |
0.369 |
|
2013 |
Goldstein T, Mena I, Anthony SJ, Medina R, Robinson PW, Greig DJ, Costa DP, Lipkin WI, Garcia-Sastre A, Boyce WM. Pandemic H1N1 influenza isolated from free-ranging Northern Elephant Seals in 2010 off the central California coast. Plos One. 8: e62259. PMID 23690933 DOI: 10.1371/Journal.Pone.0062259 |
0.36 |
|
2013 |
Perez JT, García-Sastre A, Manicassamy B. Insertion of a GFP reporter gene in influenza virus. Current Protocols in Microbiology. Unit 15G.4. PMID 23686828 DOI: 10.1002/9780471729259.Mc15G04S29 |
0.412 |
|
2013 |
Martínez-Romero C, de Vries E, Belicha-Villanueva A, Mena I, Tscherne DM, Gillespie VL, Albrecht RA, de Haan CA, García-Sastre A. Substitutions T200A and E227A in the hemagglutinin of pandemic 2009 influenza A virus increase lethality but decrease transmission. Journal of Virology. 87: 6507-11. PMID 23536663 DOI: 10.1128/JVI.00262-13 |
0.377 |
|
2013 |
Weber M, Gawanbacht A, Habjan M, Rang A, Borner C, Schmidt AM, Veitinger S, Jacob R, Devignot S, Kochs G, García-Sastre A, Weber F. Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling. Cell Host & Microbe. 13: 336-46. PMID 23498958 DOI: 10.1016/j.chom.2013.01.012 |
0.363 |
|
2013 |
Fouchier RA, García-Sastre A, Kawaoka Y. H5N1 virus: Transmission studies resume for avian flu. Nature. 493: 609. PMID 23354044 DOI: 10.1038/Nature11858 |
0.375 |
|
2013 |
Ramos I, Carnero E, Bernal-Rubio D, Seibert CW, Westera L, García-Sastre A, Fernandez-Sesma A. Contribution of double-stranded RNA and CPSF30 binding domains of influenza virus NS1 to the inhibition of type I interferon production and activation of human dendritic cells. Journal of Virology. 87: 2430-40. PMID 23255794 DOI: 10.1128/Jvi.02247-12 |
0.492 |
|
2013 |
Hartmann BM, Li W, Jia J, Patil S, Marjanovic N, Martínez-Romero C, Albrecht RA, Hayot F, García-Sastre A, Wetmur JG, Moran TM, Sealfon SC. Mouse dendritic cell (DC) influenza virus infectivity is much lower than that for human DCs and is hemagglutinin subtype dependent. Journal of Virology. 87: 1916-8. PMID 23192878 DOI: 10.1128/Jvi.02980-12 |
0.319 |
|
2012 |
Irie T, Carnero E, García-Sastre A, Harty RN. In Vivo Replication and Pathogenesis of Vesicular Stomatitis Virus Recombinant M40 Containing Ebola Virus L-Domain Sequences. Infectious Diseases. 5: 59-64. PMID 23794798 DOI: 10.4137/Idrt.S10652 |
0.375 |
|
2012 |
Rajsbaum R, Albrecht RA, Wang MK, Maharaj NP, Versteeg GA, Nistal-Villán E, García-Sastre A, Gack MU. Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein. Plos Pathogens. 8: e1003059. PMID 23209422 DOI: 10.1371/journal.ppat.1003059 |
0.495 |
|
2012 |
Martínez-Gil L, Ayllon J, Ortigoza MB, García-Sastre A, Shaw ML, Palese P. Identification of small molecules with type I interferon inducing properties by high-throughput screening. Plos One. 7: e49049. PMID 23145065 DOI: 10.1371/Journal.Pone.0049049 |
0.389 |
|
2012 |
García-Sastre A. The neuraminidase of bat influenza viruses is not a neuraminidase. Proceedings of the National Academy of Sciences of the United States of America. 109: 18635-6. PMID 23100536 DOI: 10.1073/pnas.1215857109 |
0.322 |
|
2012 |
Helft J, Manicassamy B, Guermonprez P, Hashimoto D, Silvin A, Agudo J, Brown BD, Schmolke M, Miller JC, Leboeuf M, Murphy KM, García-Sastre A, Merad M. Cross-presenting CD103+ dendritic cells are protected from influenza virus infection. The Journal of Clinical Investigation. 122: 4037-47. PMID 23041628 DOI: 10.1172/Jci60659 |
0.353 |
|
2012 |
Qiao C, Liu Q, Bawa B, Shen H, Qi W, Chen Y, Mok CK, García-Sastre A, Richt JA, Ma W. Pathogenicity and transmissibility of reassortant H9 influenza viruses with genes from pandemic H1N1 virus. The Journal of General Virology. 93: 2337-45. PMID 22875253 DOI: 10.1099/vir.0.044040-0 |
0.343 |
|
2012 |
Josset L, Engelmann F, Haberthur K, Kelly S, Park B, Kawoaka Y, García-Sastre A, Katze MG, Messaoudi I. Increased viral loads and exacerbated innate host responses in aged macaques infected with the 2009 pandemic H1N1 influenza A virus. Journal of Virology. 86: 11115-27. PMID 22855494 DOI: 10.1128/JVI.01571-12 |
0.352 |
|
2012 |
Langlois RA, Varble A, Chua MA, García-Sastre A, tenOever BR. Hematopoietic-specific targeting of influenza A virus reveals replication requirements for induction of antiviral immune responses. Proceedings of the National Academy of Sciences of the United States of America. 109: 12117-22. PMID 22778433 DOI: 10.1073/Pnas.1206039109 |
0.468 |
|
2012 |
Ayllon J, García-Sastre A, Hale BG. Influenza A viruses and PI3K: are there time, place and manner restrictions? Virulence. 3: 411-4. PMID 22722241 DOI: 10.4161/viru.20932 |
0.301 |
|
2012 |
Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Albrecht R, Blum DL, Ramos I, Fernandez-Sesma A, Edwards KM, García-Sastre A, Basler CF, Crowe JE. Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses. Journal of Virology. 86: 6334-40. PMID 22457520 DOI: 10.1128/Jvi.07158-11 |
0.361 |
|
2012 |
Maamary J, Pica N, Belicha-Villanueva A, Chou YY, Krammer F, Gao Q, García-Sastre A, Palese P. Attenuated influenza virus construct with enhanced hemagglutinin protein expression. Journal of Virology. 86: 5782-90. PMID 22398291 DOI: 10.1128/Jvi.00190-12 |
0.483 |
|
2012 |
Belicha-Villanueva A, Rodriguez-Madoz JR, Maamary J, Baum A, Bernal-Rubio D, Minguito de la Escalera M, Fernandez-Sesma A, García-Sastre A. Recombinant influenza A viruses with enhanced levels of PB1 and PA viral protein expression. Journal of Virology. 86: 5926-30. PMID 22398284 DOI: 10.1128/Jvi.06384-11 |
0.785 |
|
2012 |
Noronha JM, Liu M, Squires RB, Pickett BE, Hale BG, Air GM, Galloway SE, Takimoto T, Schmolke M, Hunt V, Klem E, García-Sastre A, McGee M, Scheuermann RH. Influenza virus sequence feature variant type analysis: evidence of a role for NS1 in influenza virus host range restriction. Journal of Virology. 86: 5857-66. PMID 22398283 DOI: 10.1128/Jvi.06901-11 |
0.399 |
|
2012 |
García-Sastre A. Working safely with H5N1 viruses. Mbio. 3: e00049-12. PMID 22396483 DOI: 10.1128/mBio.00049-12 |
0.302 |
|
2012 |
Ayllon J, Hale BG, García-Sastre A. Strain-specific contribution of NS1-activated phosphoinositide 3-kinase signaling to influenza A virus replication and virulence. Journal of Virology. 86: 5366-70. PMID 22345452 DOI: 10.1128/JVI.06722-11 |
0.364 |
|
2012 |
Ma W, Liu Q, Bawa B, Qiao C, Qi W, Shen H, Chen Y, Ma J, Li X, Webby RJ, García-Sastre A, Richt JA. The neuraminidase and matrix genes of the 2009 pandemic influenza H1N1 virus cooperate functionally to facilitate efficient replication and transmissibility in pigs. The Journal of General Virology. 93: 1261-1268. PMID 22337640 DOI: 10.1099/Vir.0.040535-0 |
0.353 |
|
2012 |
Pica N, Hai R, Krammer F, Wang TT, Maamary J, Eggink D, Tan GS, Krause JC, Moran T, Stein CR, Banach D, Wrammert J, Belshe RB, García-Sastre A, Palese P. Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses. Proceedings of the National Academy of Sciences of the United States of America. 109: 2573-8. PMID 22308500 DOI: 10.1073/Pnas.1200039109 |
0.373 |
|
2012 |
Wang M, Tscherne DM, McCullough C, Caffrey M, García-Sastre A, Rong L. Residue Y161 of influenza virus hemagglutinin is involved in viral recognition of sialylated complexes from different hosts. Journal of Virology. 86: 4455-62. PMID 22301136 DOI: 10.1128/Jvi.07187-11 |
0.421 |
|
2012 |
Oudshoorn D, van Boheemen S, Sánchez-Aparicio MT, Rajsbaum R, García-Sastre A, Versteeg GA. HERC6 is the main E3 ligase for global ISG15 conjugation in mouse cells. Plos One. 7: e29870. PMID 22272257 DOI: 10.1371/journal.pone.0029870 |
0.364 |
|
2012 |
Squires RB, Noronha J, Hunt V, García-Sastre A, Macken C, Baumgarth N, Suarez D, Pickett BE, Zhang Y, Larsen CN, Ramsey A, Zhou L, Zaremba S, Kumar S, Deitrich J, et al. Influenza research database: an integrated bioinformatics resource for influenza research and surveillance. Influenza and Other Respiratory Viruses. 6: 404-16. PMID 22260278 DOI: 10.1111/J.1750-2659.2011.00331.X |
0.345 |
|
2011 |
Guerra S, Abaitua F, Martínez-Sobrido L, Esteban M, García-Sastre A, Rodríguez D. Host-range restriction of vaccinia virus E3L deletion mutant can be overcome in vitro, but not in vivo, by expression of the influenza virus NS1 protein. Plos One. 6: e28677. PMID 22174864 DOI: 10.1371/journal.pone.0028677 |
0.49 |
|
2011 |
Muñoz-Fontela C, Pazos M, Delgado I, Murk W, Mungamuri SK, Lee SW, García-Sastre A, Moran TM, Aaronson SA. p53 serves as a host antiviral factor that enhances innate and adaptive immune responses to influenza A virus. Journal of Immunology (Baltimore, Md. : 1950). 187: 6428-36. PMID 22105999 DOI: 10.4049/Jimmunol.1101459 |
0.337 |
|
2011 |
van Kasteren PB, Beugeling C, Ninaber DK, Frias-Staheli N, van Boheemen S, García-Sastre A, Snijder EJ, Kikkert M. Arterivirus and nairovirus ovarian tumor domain-containing Deubiquitinases target activated RIG-I to control innate immune signaling. Journal of Virology. 86: 773-85. PMID 22072774 DOI: 10.1128/JVI.06277-11 |
0.81 |
|
2011 |
García-Sastre A. Induction and evasion of type I interferon responses by influenza viruses. Virus Research. 162: 12-8. PMID 22027189 DOI: 10.1016/j.virusres.2011.10.017 |
0.447 |
|
2011 |
Bortz E, García-Sastre A. Predicting the pathogenesis of influenza from genomic response: a step toward early diagnosis. Genome Medicine. 3: 67. PMID 22023877 DOI: 10.1186/gm283 |
0.383 |
|
2011 |
Hargadon KM, Zhou H, Albrecht RA, Dodd HA, García-Sastre A, Braciale TJ. Major histocompatibility complex class II expression and hemagglutinin subtype influence the infectivity of type A influenza virus for respiratory dendritic cells. Journal of Virology. 85: 11955-63. PMID 21917972 DOI: 10.1128/Jvi.05830-11 |
0.381 |
|
2011 |
Chou YY, Albrecht RA, Pica N, Lowen AC, Richt JA, García-Sastre A, Palese P, Hai R. The M segment of the 2009 new pandemic H1N1 influenza virus is critical for its high transmission efficiency in the guinea pig model. Journal of Virology. 85: 11235-41. PMID 21880744 DOI: 10.1128/Jvi.05794-11 |
0.405 |
|
2011 |
Schmolke M, Manicassamy B, Pena L, Sutton T, Hai R, Varga ZT, Hale BG, Steel J, Pérez DR, García-Sastre A. Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species. Plos Pathogens. 7: e1002186. PMID 21852950 DOI: 10.1371/Journal.Ppat.1002186 |
0.361 |
|
2011 |
Bortz E, Westera L, Maamary J, Steel J, Albrecht RA, Manicassamy B, Chase G, Martínez-Sobrido L, Schwemmle M, García-Sastre A. Host- and strain-specific regulation of influenza virus polymerase activity by interacting cellular proteins. Mbio. 2. PMID 21846828 DOI: 10.1128/Mbio.00151-11 |
0.483 |
|
2011 |
Varga ZT, Ramos I, Hai R, Schmolke M, García-Sastre A, Fernandez-Sesma A, Palese P. The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein. Plos Pathogens. 7: e1002067. PMID 21695240 DOI: 10.1371/Journal.Ppat.1002067 |
0.358 |
|
2011 |
Tscherne DM, García-Sastre A. An enzymatic assay for detection of viral entry. Current Protocols in Cell Biology. Unit 26.12. PMID 21688257 DOI: 10.1002/0471143030.cb2612s51 |
0.394 |
|
2011 |
Tisoncik JR, Billharz R, Burmakina S, Belisle SE, Proll SC, Korth MJ, García-Sastre A, Garcíia-Sastre A, Katze MG. The NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways. The Journal of General Virology. 92: 2093-104. PMID 21593271 DOI: 10.1099/vir.0.032060-0 |
0.502 |
|
2011 |
Hai R, García-Sastre A, Swayne DE, Palese P. A reassortment-incompetent live attenuated influenza virus vaccine for protection against pandemic virus strains. Journal of Virology. 85: 6832-43. PMID 21543486 DOI: 10.1128/Jvi.00609-11 |
0.397 |
|
2011 |
de Vries E, Tscherne DM, Wienholts MJ, Cobos-Jiménez V, Scholte F, García-Sastre A, Rottier PJ, de Haan CA. Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway. Plos Pathogens. 7: e1001329. PMID 21483486 DOI: 10.1371/journal.ppat.1001329 |
0.368 |
|
2011 |
Kerry PS, Ayllon J, Taylor MA, Hass C, Lewis A, García-Sastre A, Randall RE, Hale BG, Russell RJ. A transient homotypic interaction model for the influenza A virus NS1 protein effector domain. Plos One. 6: e17946. PMID 21464929 DOI: 10.1371/journal.pone.0017946 |
0.376 |
|
2011 |
Baum A, García-Sastre A. Differential recognition of viral RNA by RIG-I. Virulence. 2: 166-9. PMID 21422808 |
0.71 |
|
2011 |
Sen A, Pruijssers AJ, Dermody TS, García-Sastre A, Greenberg HB. The early interferon response to rotavirus is regulated by PKR and depends on MAVS/IPS-1, RIG-I, MDA-5, and IRF3. Journal of Virology. 85: 3717-32. PMID 21307186 DOI: 10.1128/Jvi.02634-10 |
0.41 |
|
2011 |
James TW, Frias-Staheli N, Bacik JP, Levingston Macleod JM, Khajehpour M, García-Sastre A, Mark BL. Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease. Proceedings of the National Academy of Sciences of the United States of America. 108: 2222-7. PMID 21245344 DOI: 10.1073/Pnas.1013388108 |
0.819 |
|
2011 |
Tscherne DM, García-Sastre A. Virulence determinants of pandemic influenza viruses. The Journal of Clinical Investigation. 121: 6-13. PMID 21206092 DOI: 10.1172/JCI44947 |
0.319 |
|
2010 |
Ashour J, Morrison J, Laurent-Rolle M, Belicha-Villanueva A, Plumlee CR, Bernal-Rubio D, Williams KL, Harris E, Fernandez-Sesma A, Schindler C, García-Sastre A. Mouse STAT2 restricts early dengue virus replication. Cell Host & Microbe. 8: 410-21. PMID 21075352 DOI: 10.1016/J.Chom.2010.10.007 |
0.835 |
|
2010 |
Medina RA, Manicassamy B, Stertz S, Seibert CW, Hai R, Belshe RB, Frey SE, Basler CF, Palese P, García-Sastre A. Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus. Nature Communications. 1: 28. PMID 20975689 DOI: 10.1038/Ncomms1026 |
0.349 |
|
2010 |
Wang TT, Tan GS, Hai R, Pica N, Ngai L, Ekiert DC, Wilson IA, García-Sastre A, Moran TM, Palese P. Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes. Proceedings of the National Academy of Sciences of the United States of America. 107: 18979-84. PMID 20956293 DOI: 10.1073/Pnas.1013387107 |
0.354 |
|
2010 |
Schmid S, Mordstein M, Kochs G, García-Sastre A, Tenoever BR. Transcription factor redundancy ensures induction of the antiviral state. The Journal of Biological Chemistry. 285: 42013-22. PMID 20943654 DOI: 10.1074/Jbc.M110.165936 |
0.358 |
|
2010 |
Steidle S, Martínez-Sobrido L, Mordstein M, Lienenklaus S, García-Sastre A, Stäheli P, Kochs G. Glycine 184 in nonstructural protein NS1 determines the virulence of influenza A virus strain PR8 without affecting the host interferon response. Journal of Virology. 84: 12761-70. PMID 20926573 DOI: 10.1128/JVI.00701-10 |
0.493 |
|
2010 |
Brown JN, Palermo RE, Baskin CR, Gritsenko M, Sabourin PJ, Long JP, Sabourin CL, Bielefeldt-Ohmann H, García-Sastre A, Albrecht R, Tumpey TM, Jacobs JM, Smith RD, Katze MG. Macaque proteome response to highly pathogenic avian influenza and 1918 reassortant influenza virus infections. Journal of Virology. 84: 12058-68. PMID 20844032 DOI: 10.1128/Jvi.01129-10 |
0.455 |
|
2010 |
Baum A, Sachidanandam R, García-Sastre A. Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing. Proceedings of the National Academy of Sciences of the United States of America. 107: 16303-8. PMID 20805493 DOI: 10.1073/pnas.1005077107 |
0.714 |
|
2010 |
Seibert CW, Kaminski M, Philipp J, Rubbenstroth D, Albrecht RA, Schwalm F, Stertz S, Medina RA, Kochs G, García-Sastre A, Staeheli P, Palese P. Oseltamivir-resistant variants of the 2009 pandemic H1N1 influenza A virus are not attenuated in the guinea pig and ferret transmission models. Journal of Virology. 84: 11219-26. PMID 20739532 DOI: 10.1128/Jvi.01424-10 |
0.367 |
|
2010 |
Martínez-Sobrido L, García-Sastre A. Generation of recombinant influenza virus from plasmid DNA. Journal of Visualized Experiments : Jove. PMID 20729804 DOI: 10.3791/2057 |
0.429 |
|
2010 |
Widjaja I, de Vries E, Tscherne DM, García-Sastre A, Rottier PJ, de Haan CA. Inhibition of the ubiquitin-proteasome system affects influenza A virus infection at a postfusion step. Journal of Virology. 84: 9625-31. PMID 20631148 DOI: 10.1128/JVI.01048-10 |
0.417 |
|
2010 |
Versteeg GA, García-Sastre A. Viral tricks to grid-lock the type I interferon system. Current Opinion in Microbiology. 13: 508-16. PMID 20538505 DOI: 10.1016/j.mib.2010.05.009 |
0.462 |
|
2010 |
Manicassamy B, Manicassamy S, Belicha-Villanueva A, Pisanelli G, Pulendran B, García-Sastre A. Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus. Proceedings of the National Academy of Sciences of the United States of America. 107: 11531-6. PMID 20534532 DOI: 10.1073/Pnas.0914994107 |
0.445 |
|
2010 |
Perez JT, Varble A, Sachidanandam R, Zlatev I, Manoharan M, García-Sastre A, tenOever BR. Influenza A virus-generated small RNAs regulate the switch from transcription to replication. Proceedings of the National Academy of Sciences of the United States of America. 107: 11525-30. PMID 20534471 DOI: 10.1073/pnas.1001984107 |
0.424 |
|
2010 |
Hu J, Nistal-Villán E, Voho A, Ganee A, Kumar M, Ding Y, García-Sastre A, Wetmur JG. A common polymorphism in the caspase recruitment domain of RIG-I modifies the innate immune response of human dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 424-32. PMID 20511549 DOI: 10.4049/Jimmunol.0903291 |
0.315 |
|
2010 |
Ranjan P, Jayashankar L, Deyde V, Zeng H, Davis WG, Pearce MB, Bowzard JB, Hoelscher MA, Jeisy-Scott V, Wiens ME, Gangappa S, Gubareva L, García-Sastre A, Katz JM, Tumpey TM, et al. 5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication. Virology Journal. 7: 102. PMID 20492658 DOI: 10.1186/1743-422X-7-102 |
0.365 |
|
2010 |
Ma W, Lager KM, Lekcharoensuk P, Ulery ES, Janke BH, Solórzano A, Webby RJ, García-Sastre A, Richt JA. Viral reassortment and transmission after co-infection of pigs with classical H1N1 and triple-reassortant H3N2 swine influenza viruses. The Journal of General Virology. 91: 2314-21. PMID 20484565 DOI: 10.1099/Vir.0.021402-0 |
0.367 |
|
2010 |
Schmolke M, García-Sastre A. Evasion of innate and adaptive immune responses by influenza A virus. Cellular Microbiology. 12: 873-80. PMID 20482552 DOI: 10.1111/j.1462-5822.2010.01475.x |
0.363 |
|
2010 |
Hale BG, Steel J, Medina RA, Manicassamy B, Ye J, Hickman D, Hai R, Schmolke M, Lowen AC, Perez DR, García-Sastre A. Inefficient control of host gene expression by the 2009 pandemic H1N1 influenza A virus NS1 protein. Journal of Virology. 84: 6909-22. PMID 20444891 DOI: 10.1128/Jvi.00081-10 |
0.474 |
|
2010 |
Nistal-Villán E, Gack MU, Martínez-Delgado G, Maharaj NP, Inn KS, Yang H, Wang R, Aggarwal AK, Jung JU, García-Sastre A. Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production. The Journal of Biological Chemistry. 285: 20252-61. PMID 20406818 DOI: 10.1074/Jbc.M109.089912 |
0.371 |
|
2010 |
Rose KM, Elliott R, Martínez-Sobrido L, García-Sastre A, Weiss SR. Murine coronavirus delays expression of a subset of interferon-stimulated genes. Journal of Virology. 84: 5656-69. PMID 20357099 DOI: 10.1128/JVI.00211-10 |
0.442 |
|
2010 |
Hale BG, Steel J, Manicassamy B, Medina RA, Ye J, Hickman D, Lowen AC, Perez DR, García-Sastre A. Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus. The Journal of General Virology. 91: 1737-42. PMID 20237225 DOI: 10.1099/Vir.0.020925-0 |
0.455 |
|
2010 |
Versteeg GA, Hale BG, van Boheemen S, Wolff T, Lenschow DJ, García-Sastre A. Species-specific antagonism of host ISGylation by the influenza B virus NS1 protein. Journal of Virology. 84: 5423-30. PMID 20219937 DOI: 10.1128/Jvi.02395-09 |
0.386 |
|
2010 |
García-Sastre A. Influenza virus receptor specificity: disease and transmission. The American Journal of Pathology. 176: 1584-5. PMID 20203283 DOI: 10.2353/ajpath.2010.100066 |
0.329 |
|
2010 |
Hai R, Schmolke M, Varga ZT, Manicassamy B, Wang TT, Belser JA, Pearce MB, García-Sastre A, Tumpey TM, Palese P. PB1-F2 expression by the 2009 pandemic H1N1 influenza virus has minimal impact on virulence in animal models. Journal of Virology. 84: 4442-50. PMID 20181699 DOI: 10.1128/Jvi.02717-09 |
0.4 |
|
2010 |
Manicassamy B, Medina RA, Hai R, Tsibane T, Stertz S, Nistal-Villán E, Palese P, Basler CF, García-Sastre A. Protection of mice against lethal challenge with 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 based vaccines. Plos Pathogens. 6: e1000745. PMID 20126449 DOI: 10.1371/Journal.Ppat.1000745 |
0.38 |
|
2010 |
Laurent-Rolle M, Boer EF, Lubick KJ, Wolfinbarger JB, Carmody AB, Rockx B, Liu W, Ashour J, Shupert WL, Holbrook MR, Barrett AD, Mason PW, Bloom ME, García-Sastre A, Khromykh AA, et al. The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signaling. Journal of Virology. 84: 3503-15. PMID 20106931 DOI: 10.1128/Jvi.01161-09 |
0.836 |
|
2010 |
Gack MU, Nistal-Villán E, Inn KS, García-Sastre A, Jung JU. Phosphorylation-mediated negative regulation of RIG-I antiviral activity. Journal of Virology. 84: 3220-9. PMID 20071582 DOI: 10.1128/JVI.02241-09 |
0.421 |
|
2010 |
König R, Stertz S, Zhou Y, Inoue A, Hoffmann HH, Bhattacharyya S, Alamares JG, Tscherne DM, Ortigoza MB, Liang Y, Gao Q, Andrews SE, Bandyopadhyay S, De Jesus P, Tu BP, et al. Human host factors required for influenza virus replication. Nature. 463: 813-7. PMID 20027183 DOI: 10.1038/Nature08699 |
0.476 |
|
2010 |
Hale BG, Albrecht RA, García-Sastre A. Innate immune evasion strategies of influenza viruses. Future Microbiology. 5: 23-41. PMID 20020828 DOI: 10.2217/fmb.09.108 |
0.403 |
|
2010 |
Mueller SN, Langley WA, Carnero E, García-Sastre A, Ahmed R. Immunization with live attenuated influenza viruses that express altered NS1 proteins results in potent and protective memory CD8+ T-cell responses. Journal of Virology. 84: 1847-55. PMID 19939929 DOI: 10.1128/Jvi.01317-09 |
0.452 |
|
2010 |
Martínez-Sobrido L, Cadagan R, Steel J, Basler CF, Palese P, Moran TM, García-Sastre A. Hemagglutinin-pseudotyped green fluorescent protein-expressing influenza viruses for the detection of influenza virus neutralizing antibodies. Journal of Virology. 84: 2157-63. PMID 19939917 DOI: 10.1128/Jvi.01433-09 |
0.397 |
|
2010 |
Baum A, García-Sastre A. Induction of type I interferon by RNA viruses: cellular receptors and their substrates. Amino Acids. 38: 1283-99. PMID 19882216 DOI: 10.1007/s00726-009-0374-0 |
0.715 |
|
2010 |
Tscherne DM, Manicassamy B, García-Sastre A. An enzymatic virus-like particle assay for sensitive detection of virus entry. Journal of Virological Methods. 163: 336-43. PMID 19879300 DOI: 10.1016/J.Jviromet.2009.10.020 |
0.409 |
|
2010 |
Steel J, Staeheli P, Mubareka S, García-Sastre A, Palese P, Lowen AC. Transmission of pandemic H1N1 influenza virus and impact of prior exposure to seasonal strains or interferon treatment. Journal of Virology. 84: 21-6. PMID 19828604 DOI: 10.1128/Jvi.01732-09 |
0.344 |
|
2009 |
Tscherne DM, García-Sastre A. Recent strategies to identify broadly neutralizing antibodies against influenza A virus. F1000 Biology Reports. 1: 12. PMID 20948674 DOI: 10.3410/B1-12 |
0.341 |
|
2009 |
Babiuk S, Albrecht R, Berhane Y, Marszal P, Richt JA, García-Sastre A, Pasick J, Weingartl H. 1918 and 2009 H1N1 influenza viruses are not pathogenic in birds. The Journal of General Virology. 91: 339-42. PMID 19889930 DOI: 10.1099/vir.0.016246-0 |
0.365 |
|
2009 |
Gannagé M, Dormann D, Albrecht R, Dengjel J, Torossi T, Rämer PC, Lee M, Strowig T, Arrey F, Conenello G, Pypaert M, Andersen J, García-Sastre A, Münz C. Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes. Cell Host & Microbe. 6: 367-80. PMID 19837376 DOI: 10.1016/J.Chom.2009.09.005 |
0.476 |
|
2009 |
Richt JA, García-Sastre A. Attenuated influenza virus vaccines with modified NS1 proteins. Current Topics in Microbiology and Immunology. 333: 177-95. PMID 19768406 DOI: 10.1007/978-3-540-92165-3_9 |
0.441 |
|
2009 |
Kochs G, Martínez-Sobrido L, Lienenklaus S, Weiss S, García-Sastre A, Staeheli P. Strong interferon-inducing capacity of a highly virulent variant of influenza A virus strain PR8 with deletions in the NS1 gene. The Journal of General Virology. 90: 2990-2994. PMID 19726611 DOI: 10.1099/vir.0.015727-0 |
0.505 |
|
2009 |
Guo H, Kumar P, Moran TM, Garcia-Sastre A, Zhou Y, Malarkannan S. The functional impairment of natural killer cells during influenza virus infection. Immunology and Cell Biology. 87: 579-89. PMID 19721456 DOI: 10.1038/icb.2009.60 |
0.406 |
|
2009 |
Billharz R, Zeng H, Proll SC, Korth MJ, Lederer S, Albrecht R, Goodman AG, Rosenzweig E, Tumpey TM, García-Sastre A, Katze MG. The NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathways. Journal of Virology. 83: 10557-70. PMID 19706713 DOI: 10.1128/JVI.00330-09 |
0.431 |
|
2009 |
Kuri T, Zhang X, Habjan M, Martínez-Sobrido L, García-Sastre A, Yuan Z, Weber F. Interferon priming enables cells to partially overturn the SARS coronavirus-induced block in innate immune activation. The Journal of General Virology. 90: 2686-2694. PMID 19625461 DOI: 10.1099/vir.0.013599-0 |
0.367 |
|
2009 |
Dauber B, Martínez-Sobrido L, Schneider J, Hai R, Waibler Z, Kalinke U, García-Sastre A, Wolff T. Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR. Plos Pathogens. 5: e1000473. PMID 19521506 DOI: 10.1371/Journal.Ppat.1000473 |
0.486 |
|
2009 |
Gack MU, Albrecht RA, Urano T, Inn KS, Huang IC, Carnero E, Farzan M, Inoue S, Jung JU, García-Sastre A. Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host & Microbe. 5: 439-49. PMID 19454348 DOI: 10.1016/j.chom.2009.04.006 |
0.509 |
|
2009 |
Mubareka S, Lowen AC, Steel J, Coates AL, García-Sastre A, Palese P. Transmission of influenza virus via aerosols and fomites in the guinea pig model. The Journal of Infectious Diseases. 199: 858-65. PMID 19434931 DOI: 10.1086/597073 |
0.352 |
|
2009 |
Haye K, Burmakina S, Moran T, García-Sastre A, Fernandez-Sesma A. The NS1 protein of a human influenza virus inhibits type I interferon production and the induction of antiviral responses in primary human dendritic and respiratory epithelial cells. Journal of Virology. 83: 6849-62. PMID 19403682 DOI: 10.1128/Jvi.02323-08 |
0.474 |
|
2009 |
Ashour J, Laurent-Rolle M, Shi PY, García-Sastre A. NS5 of dengue virus mediates STAT2 binding and degradation. Journal of Virology. 83: 5408-18. PMID 19279106 DOI: 10.1128/JVI.02188-08 |
0.835 |
|
2009 |
Weingartl HM, Albrecht RA, Lager KM, Babiuk S, Marszal P, Neufeld J, Embury-Hyatt C, Lekcharoensuk P, Tumpey TM, García-Sastre A, Richt JA. Experimental infection of pigs with the human 1918 pandemic influenza virus. Journal of Virology. 83: 4287-96. PMID 19224986 DOI: 10.1128/JVI.02399-08 |
0.429 |
|
2009 |
Van Hoeven N, Pappas C, Belser JA, Maines TR, Zeng H, García-Sastre A, Sasisekharan R, Katz JM, Tumpey TM. Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air. Proceedings of the National Academy of Sciences of the United States of America. 106: 3366-71. PMID 19211790 DOI: 10.1073/Pnas.0813172106 |
0.373 |
|
2009 |
Zamarin D, Martínez-Sobrido L, Kelly K, Mansour M, Sheng G, Vigil A, García-Sastre A, Palese P, Fong Y. Enhancement of oncolytic properties of recombinant newcastle disease virus through antagonism of cellular innate immune responses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 697-706. PMID 19209145 DOI: 10.1038/Mt.2008.286 |
0.802 |
|
2009 |
Lowen AC, Steel J, Mubareka S, Carnero E, García-Sastre A, Palese P. Blocking interhost transmission of influenza virus by vaccination in the guinea pig model. Journal of Virology. 83: 2803-18. PMID 19153237 DOI: 10.1128/Jvi.02424-08 |
0.348 |
|
2009 |
Steel J, Lowen AC, Pena L, Angel M, Solórzano A, Albrecht R, Perez DR, García-Sastre A, Palese P. Live attenuated influenza viruses containing NS1 truncations as vaccine candidates against H5N1 highly pathogenic avian influenza. Journal of Virology. 83: 1742-53. PMID 19073731 DOI: 10.1128/Jvi.01920-08 |
0.399 |
|
2009 |
Lai C, Struckhoff JJ, Schneider J, Martinez-Sobrido L, Wolff T, García-Sastre A, Zhang DE, Lenschow DJ. Mice lacking the ISG15 E1 enzyme UbE1L demonstrate increased susceptibility to both mouse-adapted and non-mouse-adapted influenza B virus infection. Journal of Virology. 83: 1147-51. PMID 19004958 DOI: 10.1128/Jvi.00105-08 |
0.429 |
|
2009 |
Carnero E, Li W, Borderia AV, Moltedo B, Moran T, García-Sastre A. Optimization of human immunodeficiency virus gag expression by newcastle disease virus vectors for the induction of potent immune responses. Journal of Virology. 83: 584-97. PMID 19004953 DOI: 10.1128/Jvi.01443-08 |
0.307 |
|
2008 |
Taylor SL, Frias-Staheli N, García-Sastre A, Schmaljohn CS. Hantaan virus nucleocapsid protein binds to importin alpha proteins and inhibits tumor necrosis factor alpha-induced activation of nuclear factor kappa B. Journal of Virology. 83: 1271-9. PMID 19019947 DOI: 10.1128/JVI.00986-08 |
0.805 |
|
2008 |
Hai R, Martínez-Sobrido L, Fraser KA, Ayllon J, García-Sastre A, Palese P. Influenza B virus NS1-truncated mutants: live-attenuated vaccine approach. Journal of Virology. 82: 10580-90. PMID 18768976 DOI: 10.1128/Jvi.01213-08 |
0.399 |
|
2008 |
Vigil A, Martinez O, Chua MA, García-Sastre A. Recombinant Newcastle disease virus as a vaccine vector for cancer therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1883-90. PMID 18714310 DOI: 10.1038/mt.2008.181 |
0.732 |
|
2008 |
Perrone LA, Plowden JK, García-Sastre A, Katz JM, Tumpey TM. H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice. Plos Pathogens. 4: e1000115. PMID 18670648 DOI: 10.1371/Journal.Ppat.1000115 |
0.365 |
|
2008 |
Muñoz-Fontela C, Macip S, Martínez-Sobrido L, Brown L, Ashour J, García-Sastre A, Lee SW, Aaronson SA. Transcriptional role of p53 in interferon-mediated antiviral immunity. The Journal of Experimental Medicine. 205: 1929-38. PMID 18663127 DOI: 10.1084/Jem.20080383 |
0.793 |
|
2008 |
Pappas C, Aguilar PV, Basler CF, Solórzano A, Zeng H, Perrone LA, Palese P, García-Sastre A, Katz JM, Tumpey TM. Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus. Proceedings of the National Academy of Sciences of the United States of America. 105: 3064-9. PMID 18287069 DOI: 10.1073/Pnas.0711815105 |
0.407 |
|
2008 |
Dittmann J, Stertz S, Grimm D, Steel J, García-Sastre A, Haller O, Kochs G. Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPase. Journal of Virology. 82: 3624-31. PMID 18199636 DOI: 10.1128/JVI.01753-07 |
0.433 |
|
2008 |
Steel J, Burmakina SV, Thomas C, Spackman E, García-Sastre A, Swayne DE, Palese P. A combination in-ovo vaccine for avian influenza virus and Newcastle disease virus. Vaccine. 26: 522-31. PMID 18093698 DOI: 10.1016/J.Vaccine.2007.11.032 |
0.395 |
|
2008 |
Squires B, Macken C, Garcia-Sastre A, Godbole S, Noronha J, Hunt V, Chang R, Larsen CN, Klem E, Biersack K, Scheuermann RH. BioHealthBase: informatics support in the elucidation of influenza virus host pathogen interactions and virulence. Nucleic Acids Research. 36: D497-503. PMID 17965094 DOI: 10.1093/Nar/Gkm905 |
0.352 |
|
2007 |
Frias-Staheli N, Giannakopoulos NV, Kikkert M, Taylor SL, Bridgen A, Paragas J, Richt JA, Rowland RR, Schmaljohn CS, Lenschow DJ, Snijder EJ, García-Sastre A, Virgin HW. Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses. Cell Host & Microbe. 2: 404-16. PMID 18078692 DOI: 10.1016/J.Chom.2007.09.014 |
0.838 |
|
2007 |
Vincent AL, Ma W, Lager KM, Janke BH, Webby RJ, García-Sastre A, Richt JA. Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine. Vaccine. 25: 7999-8009. PMID 17933442 DOI: 10.1016/J.Vaccine.2007.09.019 |
0.349 |
|
2007 |
Vigil A, Park MS, Martinez O, Chua MA, Xiao S, Cros JF, Martínez-Sobrido L, Woo SL, García-Sastre A. Use of reverse genetics to enhance the oncolytic properties of Newcastle disease virus. Cancer Research. 67: 8285-92. PMID 17804743 DOI: 10.1158/0008-5472.Can-07-1025 |
0.74 |
|
2007 |
Salvatore M, Garcia-Sastre A, Ruchala P, Lehrer RI, Chang T, Klotman ME. alpha-Defensin inhibits influenza virus replication by cell-mediated mechanism(s). The Journal of Infectious Diseases. 196: 835-43. PMID 17703413 DOI: 10.1086/521027 |
0.739 |
|
2007 |
Irie T, Carnero E, Okumura A, García-Sastre A, Harty RN. Modifications of the PSAP region of the matrix protein lead to attenuation of vesicular stomatitis virus in vitro and in vivo. The Journal of General Virology. 88: 2559-67. PMID 17698667 DOI: 10.1099/Vir.0.83096-0 |
0.443 |
|
2007 |
Tumpey TM, Szretter KJ, Van Hoeven N, Katz JM, Kochs G, Haller O, García-Sastre A, Staeheli P. The Mx1 gene protects mice against the pandemic 1918 and highly lethal human H5N1 influenza viruses. Journal of Virology. 81: 10818-21. PMID 17652381 DOI: 10.1128/Jvi.01116-07 |
0.36 |
|
2007 |
Quan PL, Palacios G, Jabado OJ, Conlan S, Hirschberg DL, Pozo F, Jack PJ, Cisterna D, Renwick N, Hui J, Drysdale A, Amos-Ritchie R, Baumeister E, Savy V, Lager KM, et al. Detection of respiratory viruses and subtype identification of influenza A viruses by GreeneChipResp oligonucleotide microarray. Journal of Clinical Microbiology. 45: 2359-64. PMID 17553978 DOI: 10.1128/JCM.00737-07 |
0.339 |
|
2007 |
Ghanem A, Mayer D, Chase G, Tegge W, Frank R, Kochs G, García-Sastre A, Schwemmle M. Peptide-mediated interference with influenza A virus polymerase. Journal of Virology. 81: 7801-4. PMID 17494067 DOI: 10.1128/JVI.00724-07 |
0.451 |
|
2007 |
Roth-Cross JK, Martínez-Sobrido L, Scott EP, García-Sastre A, Weiss SR. Inhibition of the alpha/beta interferon response by mouse hepatitis virus at multiple levels. Journal of Virology. 81: 7189-99. PMID 17459917 DOI: 10.1128/JVI.00013-07 |
0.317 |
|
2007 |
Kochs G, García-Sastre A, Martínez-Sobrido L. Multiple anti-interferon actions of the influenza A virus NS1 protein. Journal of Virology. 81: 7011-21. PMID 17442719 DOI: 10.1128/JVI.02581-06 |
0.515 |
|
2007 |
Grimm D, Staeheli P, Hufbauer M, Koerner I, Martínez-Sobrido L, Solórzano A, García-Sastre A, Haller O, Kochs G. Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene. Proceedings of the National Academy of Sciences of the United States of America. 104: 6806-11. PMID 17426143 DOI: 10.1073/pnas.0701849104 |
0.394 |
|
2007 |
Tenoever BR, Ng SL, Chua MA, McWhirter SM, García-Sastre A, Maniatis T. Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity. Science (New York, N.Y.). 315: 1274-8. PMID 17332413 DOI: 10.1126/Science.1136567 |
0.376 |
|
2007 |
Mayer D, Molawi K, Martínez-Sobrido L, Ghanem A, Thomas S, Baginsky S, Grossmann J, García-Sastre A, Schwemmle M. Identification of cellular interaction partners of the influenza virus ribonucleoprotein complex and polymerase complex using proteomic-based approaches. Journal of Proteome Research. 6: 672-82. PMID 17269724 DOI: 10.1021/pr060432u |
0.395 |
|
2007 |
Stertz S, Reichelt M, Spiegel M, Kuri T, Martínez-Sobrido L, García-Sastre A, Weber F, Kochs G. The intracellular sites of early replication and budding of SARS-coronavirus. Virology. 361: 304-15. PMID 17210170 DOI: 10.1016/j.virol.2006.11.027 |
0.336 |
|
2007 |
Puig-Basagoiti F, Tilgner M, Bennett CJ, Zhou Y, Muñoz-Jordán JL, García-Sastre A, Bernard KA, Shi PY. A mouse cell-adapted NS4B mutation attenuates West Nile virus RNA synthesis. Virology. 361: 229-41. PMID 17178141 DOI: 10.1016/j.virol.2006.11.012 |
0.323 |
|
2007 |
Mibayashi M, Martínez-Sobrido L, Loo YM, Cárdenas WB, Gale M, García-Sastre A. Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus. Journal of Virology. 81: 514-24. PMID 17079289 DOI: 10.1128/JVI.01265-06 |
0.417 |
|
2006 |
Kong WP, Hood C, Yang ZY, Wei CJ, Xu L, García-Sastre A, Tumpey TM, Nabel GJ. Protective immunity to lethal challenge of the 1918 pandemic influenza virus by vaccination. Proceedings of the National Academy of Sciences of the United States of America. 103: 15987-91. PMID 17043214 DOI: 10.1073/Pnas.0607564103 |
0.363 |
|
2006 |
Lowen AC, Mubareka S, Tumpey TM, García-Sastre A, Palese P. The guinea pig as a transmission model for human influenza viruses. Proceedings of the National Academy of Sciences of the United States of America. 103: 9988-92. PMID 16785447 DOI: 10.1073/Pnas.0604157103 |
0.407 |
|
2006 |
Fernandez-Sesma A, Marukian S, Ebersole BJ, Kaminski D, Park MS, Yuen T, Sealfon SC, García-Sastre A, Moran TM. Influenza virus evades innate and adaptive immunity via the NS1 protein. Journal of Virology. 80: 6295-304. PMID 16775317 DOI: 10.1128/Jvi.02381-05 |
0.5 |
|
2006 |
Park MS, Steel J, García-Sastre A, Swayne D, Palese P. Engineered viral vaccine constructs with dual specificity: avian influenza and Newcastle disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 8203-8. PMID 16717196 DOI: 10.1073/Pnas.0602566103 |
0.38 |
|
2006 |
García-Sastre A, Biron CA. Type 1 interferons and the virus-host relationship: a lesson in détente . Science (New York, N.Y.). 312: 879-82. PMID 16690858 DOI: 10.1126/Science.1125676 |
0.349 |
|
2006 |
García-Sastre A. Antiviral response in pandemic influenza viruses. Emerging Infectious Diseases. 12: 44-7. PMID 16494716 DOI: 10.3201/eid1201.051186 |
0.477 |
|
2006 |
Martinez-Sobrido L, Gitiban N, Fernandez-Sesma A, Cros J, Mertz SE, Jewell NA, Hammond S, Flano E, Durbin RK, García-Sastre A, Durbin JE. Protection against respiratory syncytial virus by a recombinant Newcastle disease virus vector. Journal of Virology. 80: 1130-9. PMID 16414990 DOI: 10.1128/Jvi.80.3.1130-1139.2006 |
0.422 |
|
2006 |
Efferson CL, Tsuda N, Kawano K, Nistal-Villán E, Sellappan S, Yu D, Murray JL, García-Sastre A, Ioannides CG. Prostate tumor cells infected with a recombinant influenza virus expressing a truncated NS1 protein activate cytolytic CD8+ cells to recognize noninfected tumor cells. Journal of Virology. 80: 383-94. PMID 16352563 DOI: 10.1128/JVI.80.1.383-394.2006 |
0.458 |
|
2005 |
Tumpey TM, García-Sastre A, Taubenberger JK, Palese P, Swayne DE, Pantin-Jackwood MJ, Schultz-Cherry S, Solórzano A, Van Rooijen N, Katz JM, Basler CF. Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice. Journal of Virology. 79: 14933-44. PMID 16282492 DOI: 10.1128/Jvi.79.23.14933-14944.2005 |
0.41 |
|
2005 |
Tumpey TM, Basler CF, Aguilar PV, Zeng H, Solórzano A, Swayne DE, Cox NJ, Katz JM, Taubenberger JK, Palese P, García-Sastre A. Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science (New York, N.Y.). 310: 77-80. PMID 16210530 DOI: 10.1126/Science.1119392 |
0.417 |
|
2005 |
Falcón AM, Fernandez-Sesma A, Nakaya Y, Moran TM, Ortín J, García-Sastre A. Attenuation and immunogenicity in mice of temperature-sensitive influenza viruses expressing truncated NS1 proteins. The Journal of General Virology. 86: 2817-21. PMID 16186237 DOI: 10.1099/vir.0.80991-0 |
0.474 |
|
2005 |
Quinlivan M, Zamarin D, García-Sastre A, Cullinane A, Chambers T, Palese P. Attenuation of equine influenza viruses through truncations of the NS1 protein. Journal of Virology. 79: 8431-9. PMID 15956587 DOI: 10.1128/Jvi.79.13.8431-8439.2005 |
0.488 |
|
2005 |
Muñoz-Jordán JL, Laurent-Rolle M, Ashour J, Martínez-Sobrido L, Ashok M, Lipkin WI, García-Sastre A. Inhibition of alpha/beta interferon signaling by the NS4B protein of flaviviruses. Journal of Virology. 79: 8004-13. PMID 15956546 DOI: 10.1128/JVI.79.13.8004-8013.2005 |
0.766 |
|
2005 |
Bourmakina SV, García-Sastre A. The morphology and composition of influenza A virus particles are not affected by low levels of M1 and M2 proteins in infected cells. Journal of Virology. 79: 7926-32. PMID 15919950 DOI: 10.1128/JVI.79.12.7926-7932.2005 |
0.413 |
|
2005 |
Solórzano A, Webby RJ, Lager KM, Janke BH, García-Sastre A, Richt JA. Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs. Journal of Virology. 79: 7535-43. PMID 15919908 DOI: 10.1128/Jvi.79.12.7535-7543.2005 |
0.485 |
|
2005 |
Bertolotti-Ciarlet A, Smith J, Strecker K, Paragas J, Altamura LA, McFalls JM, Frias-Stäheli N, García-Sastre A, Schmaljohn CS, Doms RW. Cellular localization and antigenic characterization of crimean-congo hemorrhagic fever virus glycoproteins. Journal of Virology. 79: 6152-61. PMID 15858000 DOI: 10.1128/Jvi.79.10.6152-6161.2005 |
0.774 |
|
2005 |
Cros JF, García-Sastre A, Palese P. An unconventional NLS is critical for the nuclear import of the influenza A virus nucleoprotein and ribonucleoprotein. Traffic (Copenhagen, Denmark). 6: 205-13. PMID 15702989 DOI: 10.1111/J.1600-0854.2005.00263.X |
0.316 |
|
2005 |
Spiegel M, Pichlmair A, Martínez-Sobrido L, Cros J, García-Sastre A, Haller O, Weber F. Inhibition of Beta Interferon Induction by Severe Acute Respiratory Syndrome Coronavirus Suggests a Two-Step Model for Activation of Interferon Regulatory Factor 3 Journal of Virology. 79: 2079-2086. PMID 15681410 DOI: 10.1128/Jvi.79.4.2079-2086.2005 |
0.408 |
|
2005 |
Jennings S, Martínez-Sobrido L, García-Sastre A, Weber F, Kochs G. Thogoto virus ML protein suppresses IRF3 function. Virology. 331: 63-72. PMID 15582653 DOI: 10.1016/j.virol.2004.10.015 |
0.494 |
|
2004 |
Donelan NR, Dauber B, Wang X, Basler CF, Wolff T, García-Sastre A. The N- and C-terminal domains of the NS1 protein of influenza B virus can independently inhibit IRF-3 and beta interferon promoter activation. Journal of Virology. 78: 11574-82. PMID 15479798 DOI: 10.1128/Jvi.78.21.11574-11582.2004 |
0.826 |
|
2004 |
Baskin CR, García-Sastre A, Tumpey TM, Bielefeldt-Ohmann H, Carter VS, Nistal-Villán E, Katze MG. Integration of clinical data, pathology, and cDNA microarrays in influenza virus-infected pigtailed macaques (Macaca nemestrina) Journal of Virology. 78: 10420-10432. PMID 15367608 DOI: 10.1128/JVI.78.19.10420-10432.2004 |
0.428 |
|
2004 |
Kash JC, Basler CF, García-Sastre A, Carter V, Billharz R, Swayne DE, Przygodzki RM, Taubenberger JK, Katze MG, Tumpey TM. Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus. Journal of Virology. 78: 9499-511. PMID 15308742 DOI: 10.1128/Jvi.78.17.9499-9511.2004 |
0.412 |
|
2004 |
Nakaya Y, Nakaya T, Park MS, Cros J, Imanishi J, Palese P, García-Sastre A. Induction of cellular immune responses to simian immunodeficiency virus gag by two recombinant negative-strand RNA virus vectors. Journal of Virology. 78: 9366-75. PMID 15308731 DOI: 10.1128/Jvi.78.17.9366-9375.2004 |
0.429 |
|
2004 |
Vecino WH, Quanquin NM, Martinez-Sobrido L, Fernandez-Sesma A, García-Sastre A, Jacobs WR, Fennelly GJ. Mucosal immunization with attenuated Shigella flexneri harboring an influenza hemagglutinin DNA vaccine protects mice against a lethal influenza challenge. Virology. 325: 192-9. PMID 15246259 DOI: 10.1016/J.Virol.2004.04.045 |
0.361 |
|
2004 |
Shaw ML, García-Sastre A, Palese P, Basler CF. Nipah virus V and W proteins have a common STAT1-binding domain yet inhibit STAT1 activation from the cytoplasmic and nuclear compartments, respectively. Journal of Virology. 78: 5633-41. PMID 15140960 DOI: 10.1128/Jvi.78.11.5633-5641.2004 |
0.432 |
|
2004 |
Muster T, Rajtarova J, Sachet M, Unger H, Fleischhacker R, Romirer I, Grassauer A, Url A, García-Sastre A, Wolff K, Pehamberger H, Bergmann M. Interferon resistance promotes oncolysis by influenza virus NS1-deletion mutants. International Journal of Cancer. 110: 15-21. PMID 15054864 DOI: 10.1002/ijc.20078 |
0.48 |
|
2004 |
Tumpey TM, García-Sastre A, Taubenberger JK, Palese P, Swayne DE, Basler CF. Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus. Proceedings of the National Academy of Sciences of the United States of America. 101: 3166-71. PMID 14963236 DOI: 10.1073/Pnas.0308391100 |
0.387 |
|
2004 |
Nakaya Y, Zheng H, García-Sastre A. Enhanced cellular immune responses to SIV Gag by immunization with influenza and vaccinia virus recombinants. Vaccine. 21: 2097-106. PMID 12706700 DOI: 10.1016/s0264-410x(02)00781-8 |
0.376 |
|
2003 |
Donelan NR, Basler CF, García-Sastre A. A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice. Journal of Virology. 77: 13257-66. PMID 14645582 DOI: 10.1128/Jvi.77.24.13257-13266.2003 |
0.839 |
|
2003 |
Muñoz-Jordan JL, Sánchez-Burgos GG, Laurent-Rolle M, García-Sastre A. Inhibition of interferon signaling by dengue virus. Proceedings of the National Academy of Sciences of the United States of America. 100: 14333-8. PMID 14612562 DOI: 10.1073/pnas.2335168100 |
0.799 |
|
2003 |
González-Aseguinolaza G, Nakaya Y, Molano A, Dy E, Esteban M, Rodríguez D, Rodríguez JR, Palese P, García-Sastre A, Nussenzweig RS. Induction of protective immunity against malaria by priming-boosting immunization with recombinant cold-adapted influenza and modified vaccinia Ankara viruses expressing a CD8+-T-cell epitope derived from the circumsporozoite protein of Plasmodium yoelii. Journal of Virology. 77: 11859-66. PMID 14557672 DOI: 10.1128/Jvi.77.21.11859-11866.2003 |
0.371 |
|
2003 |
Huang TG, Ebert O, Shinozaki K, García-Sastre A, Woo SL. Oncolysis of hepatic metastasis of colorectal cancer by recombinant vesicular stomatitis virus in immune-competent mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 434-40. PMID 12946316 DOI: 10.1016/S1525-0016(03)00204-1 |
0.349 |
|
2003 |
Park MS, García-Sastre A, Cros JF, Basler CF, Palese P. Newcastle disease virus V protein is a determinant of host range restriction. Journal of Virology. 77: 9522-32. PMID 12915566 DOI: 10.1128/Jvi.77.17.9522-9532.2003 |
0.411 |
|
2003 |
Flandorfer A, García-Sastre A, Basler CF, Palese P. Chimeric influenza A viruses with a functional influenza B virus neuraminidase or hemagglutinin. Journal of Virology. 77: 9116-23. PMID 12915528 DOI: 10.1128/Jvi.77.17.9116-9123.2003 |
0.403 |
|
2003 |
Ebert O, Shinozaki K, Huang TG, Savontaus MJ, García-Sastre A, Woo SL. Oncolytic vesicular stomatitis virus for treatment of orthotopic hepatocellular carcinoma in immune-competent rats. Cancer Research. 63: 3605-11. PMID 12839948 |
0.336 |
|
2003 |
Basler CF, Mikulasova A, Martinez-Sobrido L, Paragas J, Mühlberger E, Bray M, Klenk HD, Palese P, García-Sastre A. The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3. Journal of Virology. 77: 7945-56. PMID 12829834 DOI: 10.1128/Jvi.77.14.7945-7956.2003 |
0.53 |
|
2003 |
Efferson CL, Schickli J, Ko BK, Kawano K, Mouzi S, Palese P, García-Sastre A, Ioannides CG. Activation of tumor antigen-specific cytotoxic T lymphocytes (CTLs) by human dendritic cells infected with an attenuated influenza A virus expressing a CTL epitope derived from the HER-2/neu proto-oncogene. Journal of Virology. 77: 7411-24. PMID 12805440 DOI: 10.1128/Jvi.77.13.7411-7424.2003 |
0.391 |
|
2003 |
Gherardi MM, Nájera JL, Pérez-Jiménez E, Guerra S, García-Sastre A, Esteban M. Prime-boost immunization schedules based on influenza virus and vaccinia virus vectors potentiate cellular immune responses against human immunodeficiency virus Env protein systemically and in the genitorectal draining lymph nodes. Journal of Virology. 77: 7048-57. PMID 12768024 |
0.367 |
|
2003 |
Chesler DA, Muñoz-Jordán JL, Donelan N, García-Sastre A, Reiss CS. PKR is not required for interferon-gamma inhibition of VSV replication in neurons. Viral Immunology. 16: 87-96. PMID 12725691 DOI: 10.1089/088282403763635474 |
0.774 |
|
2003 |
López CB, García-Sastre A, Williams BR, Moran TM. Type I interferon induction pathway, but not released interferon, participates in the maturation of dendritic cells induced by negative-strand RNA viruses. The Journal of Infectious Diseases. 187: 1126-36. PMID 12660927 DOI: 10.1086/368381 |
0.414 |
|
2003 |
Bourmakina SV, García-Sastre A. Reverse genetics studies on the filamentous morphology of influenza A virus. The Journal of General Virology. 84: 517-527. PMID 12604801 DOI: 10.1099/vir.0.18803-0 |
0.388 |
|
2003 |
Park MS, Shaw ML, Muñoz-Jordan J, Cros JF, Nakaya T, Bouvier N, Palese P, García-Sastre A, Basler CF. Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins. Journal of Virology. 77: 1501-11. PMID 12502864 DOI: 10.1128/Jvi.77.2.1501-1511.2003 |
0.521 |
|
2002 |
Basler CF, García-Sastre A. Viruses and the type I interferon antiviral system: induction and evasion. International Reviews of Immunology. 21: 305-37. PMID 12486817 DOI: 10.1080/08830180213277 |
0.464 |
|
2002 |
Wang X, Basler CF, Williams BR, Silverman RH, Palese P, García-Sastre A. Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains. Journal of Virology. 76: 12951-62. PMID 12438621 DOI: 10.1128/Jvi.76.24.12951-12962.2002 |
0.71 |
|
2002 |
Tumpey TM, García-Sastre A, Mikulasova A, Taubenberger JK, Swayne DE, Palese P, Basler CF. Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus. Proceedings of the National Academy of Sciences of the United States of America. 99: 13849-54. PMID 12368467 DOI: 10.1073/Pnas.212519699 |
0.395 |
|
2002 |
Ludwig S, Wang X, Ehrhardt C, Zheng H, Donelan N, Planz O, Pleschka S, García-Sastre A, Heins G, Wolff T. The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors. Journal of Virology. 76: 11166-71. PMID 12368362 DOI: 10.1128/jvi.76.21.11166-11171.2002 |
0.83 |
|
2002 |
Yewdell J, García-Sastre A. Influenza virus still surprises. Current Opinion in Microbiology. 5: 414-8. PMID 12160862 DOI: 10.1016/S1369-5274(02)00346-6 |
0.479 |
|
2002 |
Geiss GK, Salvatore M, Tumpey TM, Carter VS, Wang X, Basler CF, Taubenberger JK, Bumgarner RE, Palese P, Katze MG, García-Sastre A. Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza. Proceedings of the National Academy of Sciences of the United States of America. 99: 10736-41. PMID 12149435 DOI: 10.1073/Pnas.112338099 |
0.814 |
|
2002 |
García-Sastre A. Mechanisms of inhibition of the host interferon alpha/beta-mediated antiviral responses by viruses. Microbes and Infection. 4: 647-55. PMID 12048034 DOI: 10.1016/s1286-4579(02)01583-6 |
0.348 |
|
2002 |
Mora R, Rodriguez-Boulan E, Palese P, García-Sastre A. Apical budding of a recombinant influenza A virus expressing a hemagglutinin protein with a basolateral localization signal. Journal of Virology. 76: 3544-53. PMID 11884578 DOI: 10.1128/Jvi.76.7.3544-3553.2002 |
0.433 |
|
2002 |
Salvatore M, Basler CF, Parisien JP, Horvath CM, Bourmakina S, Zheng H, Muster T, Palese P, García-Sastre A. Effects of influenza A virus NS1 protein on protein expression: the NS1 protein enhances translation and is not required for shutoff of host protein synthesis. Journal of Virology. 76: 1206-12. PMID 11773396 DOI: 10.1128/Jvi.76.3.1206-1212.2002 |
0.758 |
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