Shane M. Harding, Ph.D.
Affiliations: | 2012 | Medical Biophysics | University of Toronto, Toronto, ON, Canada |
Area:
Molecular Biology, Cell Biology, Biochemistry, Oncology, General BiophysicsGoogle:
"Shane Harding"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Robert G. Bristow | grad student | 2012 | University of Toronto | |
| (The role of 53BP1 and its phosphorylation in the DNA damage response.) | ||||
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Publications
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| Pandya P, Vendetti FP, El-Ghoubaira J, et al. (2024) Deoxyuridine-rich cytoplasmic DNA antagonizes STING-dependent innate immune responses and sensitizes resistant tumors to anti-PD-L1 therapy. Biorxiv : the Preprint Server For Biology |
| MacDonald KM, Khan S, Lin B, et al. (2024) The proteomic landscape of genotoxic stress-induced micronuclei. Molecular Cell |
| Ha CT, Tageldein MM, Harding SM. (2023) The entanglement of DNA damage and pattern recognition receptor signaling. Dna Repair. 133: 103595 |
| Chen J, Harding SM, Natesan R, et al. (2020) Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses. Cell Reports. 32: 108080 |
| MacDonald KM, Benguerfi S, Harding SM. (2020) Alerting the immune system to DNA damage: micronuclei as mediators. Essays in Biochemistry |
| Pfeifer CR, Xia Y, Zhu K, et al. (2018) Constricted migration increases DNA damage and independently represses cell cycle. Molecular Biology of the Cell. mbcE18020079 |
| Irianto J, Xia Y, Pfeifer CR, et al. (2018) Repair Factor Loss and Genome Variation in Cancer Cell Invasion Biophysical Journal. 114: 653a |
| Harding SM, Benci JL, Irianto J, et al. (2017) Mitotic progression following DNA damage enables pattern recognition within micronuclei. Nature |
| Irianto J, Xia Y, Pfeifer CR, et al. (2017) Genomic Variation in an Osteosarcoma Cell Line Caused by Pore Migration Biophysical Journal. 112: 123a |
| Irianto J, Xia Y, Pfeifer CR, et al. (2016) DNA Damage Follows Repair Factor Depletion and Portends Genome Variation in Cancer Cells after Pore Migration. Current Biology : Cb |