Darrel W. Stafford
Affiliations: | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Medical Biophysics, Molecular BiologyGoogle:
"Darrel Wayne Stafford"Bio:
Stafford, Darrel Wayne, Protein Synthesis During The First Cleavage Cycle In Sea Urchin Eggs
(1964). Dissertations from ProQuest. 27.
https://scholarlyrepository.miami.edu/dissertations/27
https://books.google.com/books?id=8bQcAQAAMAAJ
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Parents
Sign in to add mentor| Ray M. Iverson | grad student | 1964 | University of Miami (Cell Biology Tree) | |
| (Protein Synthesis During The First Cleavage Cycle In Sea Urchin Eggs.) | ||||
Children
Sign in to add trainee| Donald Blaine Sittman | grad student | 1978 | UNC Chapel Hill (Chemistry Tree) |
| Pen-Jen Lin | grad student | 2003 | UNC Chapel Hill |
Collaborators
Sign in to add collaborator| Lee G. Pedersen | collaborator | 2000- | UNC Chapel Hill (Chemistry Tree) |
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Publications
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| Jin DY, Chen X, Liu Y, et al. (2023) A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase. Nature Communications. 14: 828 |
| Hao Z, Jin DY, Chen X, et al. (2021) γ-Glutamyl carboxylase mutations differentially affect the biological function of vitamin K-dependent proteins. Blood. 137: 533-543 |
| Hao Z, Jin D, Chen X, et al. (2020) Gamma-glutamyl carboxylase mutations differentially affect the biological function of vitamin K-dependent proteins. Blood |
| Chen X, Li C, Jin D, et al. (2020) A cell-based high-throughput screen identifies drugs that cause bleeding disorders by off-targeting the vitamin K cycle. Blood |
| Hao Z, Jin DY, Stafford DW, et al. (2019) Vitamin K-dependent carboxylation of coagulation factors: insights from a cell-based functional study. Haematologica |
| Cooley B, Broze G, Mann DM, et al. (2019) Dysfunctional Endogenous FIX Impairs Prophylaxis in a Mouse Hemophilia B Model. Blood |
| Chen X, Jin DY, Stafford DW, et al. (2018) Evaluation of oral anticoagulants with vitamin K epoxide reductase in its native milieu. Blood |
| Wu S, Chen X, Jin DY, et al. (2018) Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition. Blood |
| Sinhadri BCS, Jin DY, Stafford DW, et al. (2017) Vitamin K epoxide reductase and its paralogous enzyme have different structures and functions. Scientific Reports. 7: 17632 |
| Jin DY, Ingram BO, Stafford DW, et al. (2017) Molecular basis of the first reported clinical case of congenital combined deficiency of coagulation factors. Blood |