Leonid A. Mirny
Affiliations: | Medical Engineering and Sciences | Massachusetts Institute of Technology, Cambridge, MA, United States |
Area:
Population genetics and evolutionary theory; Polymer physics theory and simulation; Statistical interpretation of genome-wide dataWebsite:
http://www.fas.harvard.edu/~biophys/Leonid_Mirny.htmGoogle:
"Leonid A. Mirny"Bio:
http://web.mit.edu/physics/people/faculty/mirny_leonid.html
http://mirnylab.mit.edu/
http://web.mit.edu/physics/people/faculty/mirny_leonid.html
http://dx.doi.org/10.1371/journal.pcbi.1002125
Leonid A. Mirny gained a PhD in biophysics from the laboratory of Eugene Shakhnovich at Harvard University where he worked on several problems in protein folding and evolution. After serving as a Junior Fellow at Harvard Society of Fellows, he joined the faculty of the Harvard-MIT Division of Health Science and Technology and the Department of Physics at MIT. The Mirny Lab has been working on a range of problems in biophysics, including analysis of biological networks, mechanism of protein-DNA search and cooperative binding, and higher-order chromatin organization.
Mean distance: 8.94 | S | N | B | C | P |
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Eugene I. Shakhnovich | grad student | 1998 | Harvard (Chemistry Tree) | |
| (Protein folding : from lattice models to real proteins) | ||||
Children
Sign in to add trainee| Jason S. Leith | grad student | (Chemistry Tree) | |
| Zeba B. Wunderlich | grad student | 2008 | Harvard (Chemistry Tree) |
| Christopher D. McFarland | grad student | 2008-2014 | MIT and Harvard (Chemistry Tree) |
| Anton Goloborodko | grad student | 2011-2018 | MIT (Chemistry Tree) |
Publications
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| Samejima K, Gibcus JH, Abraham S, et al. (2024) Rules of engagement for condensins and cohesins guide mitotic chromosome formation. Biorxiv : the Preprint Server For Biology |
| Dequeker BJH, Scherr MJ, Brandão HB, et al. (2022) MCM complexes are barriers that restrict cohesin-mediated loop extrusion. Nature |
| Banigan EJ, Mirny LA. (2020) Loop extrusion: theory meets single-molecule experiments. Current Opinion in Cell Biology. 64: 124-138 |
| Samata M, Alexiadis A, Richard G, et al. (2020) Intergenerationally Maintained Histone H4 Lysine 16 Acetylation Is Instructive for Future Gene Activation. Cell |
| Banigan EJ, van den Berg AA, Brandão HB, et al. (2020) Chromosome organization by one-sided and two-sided loop extrusion. Elife. 9 |
| Krietenstein N, Abraham S, Venev SV, et al. (2020) Ultrastructural Details of Mammalian Chromosome Architecture. Molecular Cell |
| Feodorova Y, Falk M, Mirny LA, et al. (2020) Viewing Nuclear Architecture through the Eyes of Nocturnal Mammals. Trends in Cell Biology |
| Banigan EJ, Berg AAvd, Brandão HB, et al. (2020) Author response: Chromosome organization by one-sided and two-sided loop extrusion Elife |
| AlHaj Abed J, Erceg J, Goloborodko A, et al. (2019) Highly structured homolog pairing reflects functional organization of the Drosophila genome. Nature Communications. 10: 4485 |
| Erceg J, AlHaj Abed J, Goloborodko A, et al. (2019) The genome-wide multi-layered architecture of chromosome pairing in early Drosophila embryos. Nature Communications. 10: 4486 |