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Michelle Pacholec - Publications

Affiliations: 
2005 Harvard University, Cambridge, MA, United States 
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6 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2007 Pacholec M, Sello JK, Walsh CT, Thomas MG. Formation of an aminoacyl-S-enzyme intermediate is a key step in the biosynthesis of chloramphenicol. Organic & Biomolecular Chemistry. 5: 1692-4. PMID 17520135 DOI: 10.1039/B703356G  0.567
2005 Pacholec M, Tao J, Walsh CT. CouO and NovO: C-methyltransferases for tailoring the aminocoumarin scaffold in coumermycin and novobiocin antibiotic biosynthesis. Biochemistry. 44: 14969-76. PMID 16274243 DOI: 10.1021/Bi051599O  0.516
2005 Pacholec M, Hillson NJ, Walsh CT. NovJ/NovK catalyze benzylic oxidation of a beta-hydroxyl tyrosyl-S-pantetheinyl enzyme during aminocoumarin ring formation in novobiocin biosynthesis. Biochemistry. 44: 12819-26. PMID 16171397 DOI: 10.1021/bi051297m  0.582
2005 Pacholec M, Freel Meyers CL, Oberthür M, Kahne D, Walsh CT. Characterization of the aminocoumarin ligase SimL from the simocyclinone pathway and tandem incubation with NovM,P,N from the novobiocin pathway. Biochemistry. 44: 4949-56. PMID 15779922 DOI: 10.1021/Bi047303G  0.58
2004 Pi N, Meyers CL, Pacholec M, Walsh CT, Leary JA. Mass spectrometric characterization of a three-enzyme tandem reaction for assembly and modification of the novobiocin skeleton. Proceedings of the National Academy of Sciences of the United States of America. 101: 10036-41. PMID 15218104 DOI: 10.1073/Pnas.0403526101  0.596
2003 Tao J, Hu S, Pacholec M, Walsh CT. Synthesis of proposed oxidation-cyclization-methylation intermediates of the coumarin antibiotic biosynthetic pathway. Organic Letters. 5: 3233-6. PMID 12943395 DOI: 10.1021/Ol035101R  0.499
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