| Year |
Citation |
Score |
| 2023 |
Ordonez-Rubiano SC, Maschinot CA, Wang S, Sood S, Baracaldo-Lancheros LF, Strohmier BP, McQuade AJ, Smith BC, Dykhuizen EC. Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer. Journal of Medicinal Chemistry. 66: 11250-11270. PMID 37552884 DOI: 10.1021/acs.jmedchem.3c00671 |
0.322 |
|
| 2022 |
Shishodia S, Nuñez R, Strohmier BP, Bursch KL, Goetz CJ, Olp MD, Jensen DR, Fenske TG, Ordonez-Rubiano SC, Blau ME, Roach MK, Peterson FC, Volkman BF, Dykhuizen EC, Smith BC. Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening. Journal of Medicinal Chemistry. PMID 36227159 DOI: 10.1021/acs.jmedchem.2c00864 |
0.327 |
|
| 2021 |
Milosevich N, Wilson CR, Brown TM, Alpsoy A, Wang S, Connelly KE, Sinclair KAD, Ponio FR, Hof R, Dykhuizen EC, Hof F. Polycomb paralog chromodomain inhibitors active against both CBX6 and CBX8. Chemmedchem. PMID 34174168 DOI: 10.1002/cmdc.202100262 |
0.368 |
|
| 2020 |
Chory EJ, Kirkland JG, Chang CY, D'Andrea VD, Gourisankar S, Dykhuizen EC, Crabtree GR. Chemical Inhibitors of a Selective SWI/SNF Function Synergize with ATR Inhibition in Cancer Cell Killing. Acs Chemical Biology. PMID 32369697 DOI: 10.1021/Acschembio.0C00312 |
0.426 |
|
| 2020 |
Kurz L, Miklyaeva A, Skowron MA, Overbeck N, Poschmann G, Becker T, Eul K, Kurz T, Schönberger S, Calaminus G, Stühler K, Dykhuizen E, Albers P, Nettersheim D. Regulates Transcription and the Epigenetic Landscape via POLE and DMAP1 while Deficiency or Pharmacological Inhibition Sensitizes Germ Cell Tumor Cells to ATR Inhibition. Cancers. 12. PMID 32272809 DOI: 10.3390/Cancers12040905 |
0.421 |
|
| 2019 |
Wang S, Denton KE, Hobbs KF, Weaver T, McFarlane JMB, Connelly KE, Gignac MC, Milosevich N, Hof F, Paci I, Musselman CA, Dykhuizen EC, Krusemark CJ. Optimization of Ligands using Focused DNA-encoded Libraries to Develop a Selective, Cell-permeable CBX8 Chromodomain Inhibitor. Acs Chemical Biology. PMID 31755685 DOI: 10.1021/Acschembio.9B00654 |
0.441 |
|
| 2019 |
Cai B, Kim D, Akhand S, Sun Y, Cassell R, Alpsoy A, Dykhuizen EC, van Rijn RM, Wendt MK, Krusemark C. Selection of DNA-encoded Libraries to Protein Targets Within and On Living Cells. Journal of the American Chemical Society. PMID 31613623 DOI: 10.1021/Jacs.9B08085 |
0.42 |
|
| 2019 |
Porter EG, Dhiman A, Chowdhury B, Carter BC, Lin H, Stewart JC, Kazemian M, Wendt MK, Dykhuizen EC. PBRM1 Regulates Stress Response in Epithelial Cells. Iscience. 15: 196-210. PMID 31077944 DOI: 10.1016/J.Isci.2019.04.027 |
0.338 |
|
| 2019 |
Kulkarni RA, Bak DW, Wei D, Bergholtz SE, Briney CA, Shrimp JH, Alpsoy A, Thorpe AL, Bavari AE, Crooks DR, Levy M, Florens L, Washburn MP, Frizzell N, Dykhuizen EC, et al. A chemoproteomic portrait of the oncometabolite fumarate. Nature Chemical Biology. PMID 30718813 DOI: 10.1038/S41589-018-0217-Y |
0.33 |
|
| 2019 |
Weaver TM, Liu J, Connelly KE, Coble C, Varzavand K, Dykhuizen EC, Musselman CA. The EZH2 SANT1 domain is a histone reader providing sensitivity to the modification state of the H4 tail. Scientific Reports. 9: 987. PMID 30700785 DOI: 10.1038/S41598-018-37699-W |
0.332 |
|
| 2018 |
Connelly KE, Weaver TM, Alpsoy A, Gu BX, Musselman CA, Dykhuizen EC. Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association. Nucleic Acids Research. PMID 30597065 DOI: 10.1093/Nar/Gky1290 |
0.342 |
|
| 2018 |
Torres-Zelada EF, Stephenson RE, Alpsoy A, Anderson BD, Swanson SK, Florens L, Dykhuizen EC, Washburn MP, Weake VM. The Dbf4 ortholog Chiffon forms a complex with Gcn5 that is necessary for histone acetylation and viability. Journal of Cell Science. PMID 30559249 DOI: 10.1242/Jcs.214072 |
0.415 |
|
| 2018 |
Marian CA, Stoszko M, Wang L, Leighty MW, de Crignis E, Maschinot CA, Gatchalian J, Carter BC, Chowdhury B, Hargreaves DC, Duvall JR, Crabtree GR, Mahmoudi T, Dykhuizen EC. Small Molecule Targeting of Specific BAF (mSWI/SNF) Complexes for HIV Latency Reversal. Cell Chemical Biology. PMID 30197195 DOI: 10.1016/J.Chembiol.2018.08.004 |
0.377 |
|
| 2018 |
Soto-Velasquez M, Hayes MP, Alpsoy A, Dykhuizen EC, Watts VJ. A Novel CRISPR/Cas9-Based Cellular Model to Explore Adenylyl Cyclase and Cyclic AMP Signaling. Molecular Pharmacology. PMID 29950405 DOI: 10.1124/Mol.118.111849 |
0.355 |
|
| 2018 |
Connelly KE, Hedrick V, Sobreira TJP, Dykhuizen EC, Aryal UK. Analysis of Human Nuclear Protein Complexes by Quantitative Mass Spectrometry Profiling. Proteomics. e1700427. PMID 29655301 DOI: 10.1002/Pmic.201700427 |
0.305 |
|
| 2018 |
Alpsoy A, Dykhuizen EC. Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes. The Journal of Biological Chemistry. PMID 29374058 DOI: 10.1074/Jbc.Ra117.001065 |
0.407 |
|
| 2017 |
Porter EG, Connelly KE, Dykhuizen EC. Sequential Salt Extractions for the Analysis of Bulk Chromatin Binding Properties of Chromatin Modifying Complexes. Journal of Visualized Experiments : Jove. PMID 28994797 DOI: 10.3791/55369 |
0.402 |
|
| 2017 |
Porter EG, Dykhuizen EC. Individual Bromodomains of Polybromo-1 Contribute to Chromatin Association and Tumor Suppression in Clear Cell Renal Carcinoma. The Journal of Biological Chemistry. PMID 28053089 DOI: 10.1074/Jbc.M116.746875 |
0.387 |
|
| 2016 |
Connelly KE, Dykhuizen EC. Compositional and functional diversity of canonical PRC1 complexes in mammals. Biochimica Et Biophysica Acta. PMID 28007606 DOI: 10.1016/J.Bbagrm.2016.12.006 |
0.301 |
|
| 2016 |
Chowdhury B, Porter EG, Stewart JC, Ferreira CR, Schipma MJ, Dykhuizen EC. PBRM1 Regulates the Expression of Genes Involved in Metabolism and Cell Adhesion in Renal Clear Cell Carcinoma. Plos One. 11: e0153718. PMID 27100670 DOI: 10.1371/Journal.Pone.0153718 |
0.395 |
|
| 2016 |
Stoszko M, De Crignis E, Rokx C, Khalid MM, Lungu C, Palstra RJ, Kan TW, Boucher C, Verbon A, Dykhuizen EC, Mahmoudi T. Small Molecule Inhibitors of BAF; A Promising Family of Compounds in HIV-1 Latency Reversal. Ebiomedicine. 3: 108-21. PMID 26870822 DOI: 10.1016/J.Ebiom.2015.11.047 |
0.317 |
|
| 2013 |
Dykhuizen EC, Hargreaves DC, Miller EL, Cui K, Korshunov A, Kool M, Pfister S, Cho YJ, Zhao K, Crabtree GR. BAF complexes facilitate decatenation of DNA by topoisomerase IIα. Nature. 497: 624-7. PMID 23698369 DOI: 10.1038/Nature12146 |
0.382 |
|
| 2013 |
Dykhuizen E, Hargreaves D, Miller E, Cui K, Korshunov A, Kool M, Pfister S, Cho Y, Zhao K, Crabtree G. Abstract PR08: mSWI/SNF (BAF) complexes facilitate decatentation of DNA by topoisomerase IIα Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-Pr08 |
0.403 |
|
| 2012 |
Dykhuizen EC, Carmody LC, Tolliday N, Crabtree GR, Palmer MA. Screening for inhibitors of an essential chromatin remodeler in mouse embryonic stem cells by monitoring transcriptional regulation. Journal of Biomolecular Screening. 17: 1221-30. PMID 22853929 DOI: 10.1177/1087057112455060 |
0.423 |
|
| 2009 |
Dykhuizen EC, Kiessling LL. Potent ligands for prokaryotic UDP-galactopyranose mutase that exploit an enzyme subsite. Organic Letters. 11: 193-6. PMID 19067595 DOI: 10.1021/Ol802094P |
0.525 |
|
| 2008 |
Dykhuizen EC, May JF, Tongpenyai A, Kiessling LL. Inhibitors of UDP-galactopyranose mutase thwart mycobacterial growth. Journal of the American Chemical Society. 130: 6706-7. PMID 18447352 DOI: 10.1021/ja8018687 |
0.587 |
|
| 2007 |
Carlson CB, Mowery P, Owen RM, Dykhuizen EC, Kiessling LL. Selective tumor cell targeting using low-affinity, multivalent interactions. Acs Chemical Biology. 2: 119-27. PMID 17291050 DOI: 10.1021/Cb6003788 |
0.513 |
|
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